FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3037, 1150 aa 1>>>pF1KB3037 1150 - 1150 aa - 1150 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7353+/-0.000422; mu= 7.6634+/- 0.027 mean_var=184.4495+/-37.229, 0's: 0 Z-trim(117.0): 18 B-trim: 0 in 0/55 Lambda= 0.094436 statistics sampled from 28577 (28595) to 28577 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.335), width: 16 Scan time: 17.300 The best scores are: opt bits E(85289) NP_002709 (OMIM: 604944) serine/threonine-protein (1150) 7632 1053.1 0 XP_011511258 (OMIM: 604944) PREDICTED: serine/thre (1150) 7632 1053.1 0 XP_006713749 (OMIM: 604944) PREDICTED: serine/thre (1150) 7632 1053.1 0 XP_016862276 (OMIM: 604944) PREDICTED: serine/thre (1061) 4319 601.7 7.6e-171 NP_871626 (OMIM: 604944) serine/threonine-protein ( 529) 3324 466.0 2.8e-130 NP_001177376 (OMIM: 604944) serine/threonine-prote ( 414) 2823 397.7 7.9e-110 NP_037371 (OMIM: 300339) serine/threonine-protein ( 575) 1985 283.6 2.4e-75 XP_011544479 (OMIM: 300339) PREDICTED: serine/thre ( 565) 1971 281.7 9e-75 XP_011543932 (OMIM: 300339) PREDICTED: serine/thre ( 565) 1971 281.7 9e-75 XP_016876878 (OMIM: 615902) PREDICTED: serine/thre ( 401) 432 71.9 8.9e-12 NP_060387 (OMIM: 615902) serine/threonine-protein ( 453) 432 71.9 9.8e-12 XP_005267839 (OMIM: 615902) PREDICTED: serine/thre ( 453) 432 71.9 9.8e-12 NP_001292084 (OMIM: 615902) serine/threonine-prote ( 343) 427 71.2 1.3e-11 NP_001292085 (OMIM: 615902) serine/threonine-prote ( 343) 427 71.2 1.3e-11 XP_016876877 (OMIM: 615902) PREDICTED: serine/thre ( 407) 214 42.2 0.0079 >>NP_002709 (OMIM: 604944) serine/threonine-protein phos (1150 aa) initn: 7632 init1: 7632 opt: 7632 Z-score: 5627.1 bits: 1053.1 E(85289): 0 Smith-Waterman score: 7632; 100.0% identity (100.0% similar) in 1150 aa overlap (1-1150:1-1150) 10 20 30 40 50 60 pF1KB3 MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFTHGIDCIVVHHSVCADLLHIPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFTHGIDCIVVHHSVCADLLHIPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SQFKDADLNSMFLPHENGLSSAEGDYPQQAFTGIPRVKRGSTFQNTYNLKDIAGEAISFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SQFKDADLNSMFLPHENGLSSAEGDYPQQAFTGIPRVKRGSTFQNTYNLKDIAGEAISFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SGKIKEFSFEKLKNSNHAAYRKGRKVKSDSFNRRSVDLDLLCGHYNNDGNAPSFGLLRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SGKIKEFSFEKLKNSNHAAYRKGRKVKSDSFNRRSVDLDLLCGHYNNDGNAPSFGLLRSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SVEEKPLSHRNSLDTNLTSMFLQNFSEEDLVTQILEKHKIDNFSSGTDIKMCLDILLKCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SVEEKPLSHRNSLDTNLTSMFLQNFSEEDLVTQILEKHKIDNFSSGTDIKMCLDILLKCS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 EDLKKCTDIIKQCIKKKSGSSISEGSGNDTISSSETVYMNVMTRLASYLKKLPFEFMQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EDLKKCTDIIKQCIKKKSGSSISEGSGNDTISSSETVYMNVMTRLASYLKKLPFEFMQSG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NNEALDLTELISNMPSLQLTPFSPVFGTEQPPKYEDVVQLSASDSGRFQTIELQNDKPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NNEALDLTELISNMPSLQLTPFSPVFGTEQPPKYEDVVQLSASDSGRFQTIELQNDKPNS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 RKMDTVQSIPNNSTNSLYNLEVNDPRTLKAVQVQSQSLTMNPLENVSSDDLMETLYIEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RKMDTVQSIPNNSTNSLYNLEVNDPRTLKAVQVQSQSLTMNPLENVSSDDLMETLYIEEE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 SDGKKALDKGQKTENGPSHELLKVNEHRAEFPEHATHLKKCPTPMQNEIGKIFEKSFVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SDGKKALDKGQKTENGPSHELLKVNEHRAEFPEHATHLKKCPTPMQNEIGKIFEKSFVNL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 PKEDCKSKVSKFEEGDQRDFTNSSSQEEIDKLLMDLESFSQKMETSLREPLAKGKNSNFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PKEDCKSKVSKFEEGDQRDFTNSSSQEEIDKLLMDLESFSQKMETSLREPLAKGKNSNFL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 NSHSQLTGQTLVDLEPKSKVSSPIEKVSPSCLTRIIETNGHKIEEEDRALLLRILESIED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NSHSQLTGQTLVDLEPKSKVSSPIEKVSPSCLTRIIETNGHKIEEEDRALLLRILESIED 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 FAQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FAQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 PEVIKIQNKPEKKPGTPLPPPATSPSSPRPLSPVPHVNNVVNAPLSINIPRFYFPEGLPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PEVIKIQNKPEKKPGTPLPPPATSPSSPRPLSPVPHVNNVVNAPLSINIPRFYFPEGLPD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 TCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 QSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 FHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 YVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYAD 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 FVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB3 LLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB3 PEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEK 1090 1100 1110 1120 1130 1140 1150 pF1KB3 CGKLQSVDEE :::::::::: NP_002 CGKLQSVDEE 1150 >>XP_011511258 (OMIM: 604944) PREDICTED: serine/threonin (1150 aa) initn: 7632 init1: 7632 opt: 7632 Z-score: 5627.1 bits: 1053.1 E(85289): 0 Smith-Waterman score: 7632; 100.0% identity (100.0% similar) in 1150 aa overlap (1-1150:1-1150) 10 20 30 40 50 60 pF1KB3 MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFTHGIDCIVVHHSVCADLLHIPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFTHGIDCIVVHHSVCADLLHIPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SQFKDADLNSMFLPHENGLSSAEGDYPQQAFTGIPRVKRGSTFQNTYNLKDIAGEAISFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQFKDADLNSMFLPHENGLSSAEGDYPQQAFTGIPRVKRGSTFQNTYNLKDIAGEAISFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SGKIKEFSFEKLKNSNHAAYRKGRKVKSDSFNRRSVDLDLLCGHYNNDGNAPSFGLLRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGKIKEFSFEKLKNSNHAAYRKGRKVKSDSFNRRSVDLDLLCGHYNNDGNAPSFGLLRSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SVEEKPLSHRNSLDTNLTSMFLQNFSEEDLVTQILEKHKIDNFSSGTDIKMCLDILLKCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVEEKPLSHRNSLDTNLTSMFLQNFSEEDLVTQILEKHKIDNFSSGTDIKMCLDILLKCS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 EDLKKCTDIIKQCIKKKSGSSISEGSGNDTISSSETVYMNVMTRLASYLKKLPFEFMQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDLKKCTDIIKQCIKKKSGSSISEGSGNDTISSSETVYMNVMTRLASYLKKLPFEFMQSG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NNEALDLTELISNMPSLQLTPFSPVFGTEQPPKYEDVVQLSASDSGRFQTIELQNDKPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNEALDLTELISNMPSLQLTPFSPVFGTEQPPKYEDVVQLSASDSGRFQTIELQNDKPNS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 RKMDTVQSIPNNSTNSLYNLEVNDPRTLKAVQVQSQSLTMNPLENVSSDDLMETLYIEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKMDTVQSIPNNSTNSLYNLEVNDPRTLKAVQVQSQSLTMNPLENVSSDDLMETLYIEEE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 SDGKKALDKGQKTENGPSHELLKVNEHRAEFPEHATHLKKCPTPMQNEIGKIFEKSFVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDGKKALDKGQKTENGPSHELLKVNEHRAEFPEHATHLKKCPTPMQNEIGKIFEKSFVNL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 PKEDCKSKVSKFEEGDQRDFTNSSSQEEIDKLLMDLESFSQKMETSLREPLAKGKNSNFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKEDCKSKVSKFEEGDQRDFTNSSSQEEIDKLLMDLESFSQKMETSLREPLAKGKNSNFL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 NSHSQLTGQTLVDLEPKSKVSSPIEKVSPSCLTRIIETNGHKIEEEDRALLLRILESIED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSHSQLTGQTLVDLEPKSKVSSPIEKVSPSCLTRIIETNGHKIEEEDRALLLRILESIED 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 FAQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FAQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 PEVIKIQNKPEKKPGTPLPPPATSPSSPRPLSPVPHVNNVVNAPLSINIPRFYFPEGLPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEVIKIQNKPEKKPGTPLPPPATSPSSPRPLSPVPHVNNVVNAPLSINIPRFYFPEGLPD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 TCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 QSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 FHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 YVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYAD 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 FVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB3 LLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB3 PEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEK 1090 1100 1110 1120 1130 1140 1150 pF1KB3 CGKLQSVDEE :::::::::: XP_011 CGKLQSVDEE 1150 >>XP_006713749 (OMIM: 604944) PREDICTED: serine/threonin (1150 aa) initn: 7632 init1: 7632 opt: 7632 Z-score: 5627.1 bits: 1053.1 E(85289): 0 Smith-Waterman score: 7632; 100.0% identity (100.0% similar) in 1150 aa overlap (1-1150:1-1150) 10 20 30 40 50 60 pF1KB3 MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFTHGIDCIVVHHSVCADLLHIPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFTHGIDCIVVHHSVCADLLHIPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SQFKDADLNSMFLPHENGLSSAEGDYPQQAFTGIPRVKRGSTFQNTYNLKDIAGEAISFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQFKDADLNSMFLPHENGLSSAEGDYPQQAFTGIPRVKRGSTFQNTYNLKDIAGEAISFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SGKIKEFSFEKLKNSNHAAYRKGRKVKSDSFNRRSVDLDLLCGHYNNDGNAPSFGLLRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGKIKEFSFEKLKNSNHAAYRKGRKVKSDSFNRRSVDLDLLCGHYNNDGNAPSFGLLRSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SVEEKPLSHRNSLDTNLTSMFLQNFSEEDLVTQILEKHKIDNFSSGTDIKMCLDILLKCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SVEEKPLSHRNSLDTNLTSMFLQNFSEEDLVTQILEKHKIDNFSSGTDIKMCLDILLKCS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 EDLKKCTDIIKQCIKKKSGSSISEGSGNDTISSSETVYMNVMTRLASYLKKLPFEFMQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EDLKKCTDIIKQCIKKKSGSSISEGSGNDTISSSETVYMNVMTRLASYLKKLPFEFMQSG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NNEALDLTELISNMPSLQLTPFSPVFGTEQPPKYEDVVQLSASDSGRFQTIELQNDKPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NNEALDLTELISNMPSLQLTPFSPVFGTEQPPKYEDVVQLSASDSGRFQTIELQNDKPNS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 RKMDTVQSIPNNSTNSLYNLEVNDPRTLKAVQVQSQSLTMNPLENVSSDDLMETLYIEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RKMDTVQSIPNNSTNSLYNLEVNDPRTLKAVQVQSQSLTMNPLENVSSDDLMETLYIEEE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 SDGKKALDKGQKTENGPSHELLKVNEHRAEFPEHATHLKKCPTPMQNEIGKIFEKSFVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SDGKKALDKGQKTENGPSHELLKVNEHRAEFPEHATHLKKCPTPMQNEIGKIFEKSFVNL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 PKEDCKSKVSKFEEGDQRDFTNSSSQEEIDKLLMDLESFSQKMETSLREPLAKGKNSNFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PKEDCKSKVSKFEEGDQRDFTNSSSQEEIDKLLMDLESFSQKMETSLREPLAKGKNSNFL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 NSHSQLTGQTLVDLEPKSKVSSPIEKVSPSCLTRIIETNGHKIEEEDRALLLRILESIED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NSHSQLTGQTLVDLEPKSKVSSPIEKVSPSCLTRIIETNGHKIEEEDRALLLRILESIED 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 FAQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FAQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 PEVIKIQNKPEKKPGTPLPPPATSPSSPRPLSPVPHVNNVVNAPLSINIPRFYFPEGLPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PEVIKIQNKPEKKPGTPLPPPATSPSSPRPLSPVPHVNNVVNAPLSINIPRFYFPEGLPD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 TCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 QSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 FHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 YVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYAD 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 FVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB3 LLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB3 PEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEK 1090 1100 1110 1120 1130 1140 1150 pF1KB3 CGKLQSVDEE :::::::::: XP_006 CGKLQSVDEE 1150 >>XP_016862276 (OMIM: 604944) PREDICTED: serine/threonin (1061 aa) initn: 4319 init1: 4319 opt: 4319 Z-score: 3188.2 bits: 601.7 E(85289): 7.6e-171 Smith-Waterman score: 6832; 92.3% identity (92.3% similar) in 1150 aa overlap (1-1150:1-1061) 10 20 30 40 50 60 pF1KB3 MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFTHGIDCIVVHHSVCADLLHIPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFTHGIDCIVVHHSVCADLLHIPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SQFKDADLNSMFLPHENGLSSAEGDYPQQAFTGIPRVKRGSTFQNTYNLKDIAGEAISFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQFKDADLNSMFLPHENGLSSAEGDYPQQAFTGIPRVKRGSTFQNTYNLKDIAGEAISFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SGKIKEFSFEKLKNSNHAAYRKGRKVKSDSFNRRSVDLDLLCGHYNNDGNAPSFGLLRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGKIKEFSFEKLKNSNHAAYRKGRKVKSDSFNRRSVDLDLLCGHYNNDGNAPSFGLLRSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SVEEKPLSHRNSLDTNLTSMFLQNFSEEDLVTQILEKHKIDNFSSGTDIKMCLDILLKCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVEEKPLSHRNSLDTNLTSMFLQNFSEEDLVTQILEKHKIDNFSSGTDIKMCLDILLKCS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 EDLKKCTDIIKQCIKKKSGSSISEGSGNDTISSSETVYMNVMTRLASYLKKLPFEFMQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDLKKCTDIIKQCIKKKSGSSISEGSGNDTISSSETVYMNVMTRLASYLKKLPFEFMQSG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NNEALDLTELISNMPSLQLTPFSPVFGTEQPPKYEDVVQLSASDSGRFQTIELQNDKPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNEALDLTELISNMPSLQLTPFSPVFGTEQPPKYEDVVQLSASDSGRFQTIELQNDKPNS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 RKMDTVQSIPNNSTNSLYNLEVNDPRTLKAVQVQSQSLTMNPLENVSSDDLMETLYIEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKMDTVQSIPNNSTNSLYNLEVNDPRTLKAVQVQSQSLTMNPLENVSSDDLMETLYIEEE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 SDGKKALDKGQKTENGPSHELLKVNEHRAEFPEHATHLKKCPTPMQNEIGKIFEKSFVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDGKKALDKGQKTENGPSHELLKVNEHRAEFPEHATHLKKCPTPMQNEIGKIFEKSFVNL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 PKEDCKSKVSKFEEGDQRDFTNSSSQEEIDKLLMDLESFSQKMETSLREPLAKGKNSNFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKEDCKSKVSKFEEGDQRDFTNSSSQEEIDKLLMDLESFSQKMETSLREPLAKGKNSNFL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 NSHSQLTGQTLVDLEPKSKVSSPIEKVSPSCLTRIIETNGHKIEEEDRALLLRILESIED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSHSQLTGQTLVDLEPKSKVSSPIEKVSPSCLTRIIETNGHKIEEEDRALLLRILESIED 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 FAQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 PEVIKIQNKPEKKPGTPLPPPATSPSSPRPLSPVPHVNNVVNAPLSINIPRFYFPEGLPD ::::: XP_016 PEVIK------------------------------------------------------- 730 740 750 760 770 780 pF1KB3 TCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTA :::::::::::::::::::::::::: XP_016 ----------------------------------VCGCPLYWKAPMFRAAGGEKTGFVTA 670 680 690 790 800 810 820 830 840 pF1KB3 QSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPE 700 710 720 730 740 750 850 860 870 880 890 900 pF1KB3 FHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHF 760 770 780 790 800 810 910 920 930 940 950 960 pF1KB3 YVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYAD 820 830 840 850 860 870 970 980 990 1000 1010 1020 pF1KB3 FVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHD 880 890 900 910 920 930 1030 1040 1050 1060 1070 1080 pF1KB3 LLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDG 940 950 960 970 980 990 1090 1100 1110 1120 1130 1140 pF1KB3 PEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEK 1000 1010 1020 1030 1040 1050 1150 pF1KB3 CGKLQSVDEE :::::::::: XP_016 CGKLQSVDEE 1060 >>NP_871626 (OMIM: 604944) serine/threonine-protein phos (529 aa) initn: 3323 init1: 3323 opt: 3324 Z-score: 2460.0 bits: 466.0 E(85289): 2.8e-130 Smith-Waterman score: 3324; 99.0% identity (99.2% similar) in 493 aa overlap (658-1150:41-529) 630 640 650 660 670 680 pF1KB3 TLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQTPEVIKIQNKPEKKPGTPLPPPATSPSS ::: .:::::::::::::::::::::: NP_871 DPDLRGELAFLARGCDFVLPSRFKKRLKSFQQT----QIQNKPEKKPGTPLPPPATSPSS 20 30 40 50 60 690 700 710 720 730 740 pF1KB3 PRPLSPVPHVNNVVNAPLSINIPRFYFPEGLPDTCSNHEQTLSRIETAFMDIEEQKADIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 PRPLSPVPHVNNVVNAPLSINIPRFYFPEGLPDTCSNHEQTLSRIETAFMDIEEQKADIY 70 80 90 100 110 120 750 760 770 780 790 800 pF1KB3 EMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICLLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 EMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICLLAK 130 140 150 160 170 180 810 820 830 840 850 860 pF1KB3 PNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 PNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITS 190 200 210 220 230 240 870 880 890 900 910 920 pF1KB3 TEIRKSNFLQTLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 TEIRKSNFLQTLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYN 250 260 270 280 290 300 930 940 950 960 970 980 pF1KB3 DQASSSRIIERIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 DQASSSRIIERIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVD 310 320 330 340 350 360 990 1000 1010 1020 1030 1040 pF1KB3 GDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 GDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRM 370 380 390 400 410 420 1050 1060 1070 1080 1090 1100 pF1KB3 AHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 AHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQF 430 440 450 460 470 480 1110 1120 1130 1140 1150 pF1KB3 QEGFEDYETDEPASPSEFGNKSNKILSASLPEKCGKLQSVDEE ::::::::::::::::::::::::::::::::::::::::::: NP_871 QEGFEDYETDEPASPSEFGNKSNKILSASLPEKCGKLQSVDEE 490 500 510 520 >>NP_001177376 (OMIM: 604944) serine/threonine-protein p (414 aa) initn: 2823 init1: 2823 opt: 2823 Z-score: 2092.7 bits: 397.7 E(85289): 7.9e-110 Smith-Waterman score: 2823; 100.0% identity (100.0% similar) in 414 aa overlap (737-1150:1-414) 710 720 730 740 750 760 pF1KB3 INIPRFYFPEGLPDTCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCGCPLYWKAPM :::::::::::::::::::::::::::::: NP_001 MDIEEQKADIYEMGKIAKVCGCPLYWKAPM 10 20 30 770 780 790 800 810 820 pF1KB3 FRAAGGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FRAAGGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVV 40 50 60 70 80 90 830 840 850 860 870 880 pF1KB3 DTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEE 100 110 120 130 140 150 890 900 910 920 930 940 pF1KB3 DINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTR 160 170 180 190 200 210 950 960 970 980 990 1000 pF1KB3 GKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCE 220 230 240 250 260 270 1010 1020 1030 1040 1050 1060 pF1KB3 RMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQ 280 290 300 310 320 330 1070 1080 1090 1100 1110 1120 pF1KB3 RDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFG 340 350 360 370 380 390 1130 1140 1150 pF1KB3 NKSNKILSASLPEKCGKLQSVDEE :::::::::::::::::::::::: NP_001 NKSNKILSASLPEKCGKLQSVDEE 400 410 >>NP_037371 (OMIM: 300339) serine/threonine-protein phos (575 aa) initn: 2033 init1: 1985 opt: 1985 Z-score: 1473.6 bits: 283.6 E(85289): 2.4e-75 Smith-Waterman score: 2019; 58.4% identity (80.6% similar) in 505 aa overlap (632-1112:27-528) 610 620 630 640 650 660 pF1KB3 AQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT- :.: :. : . ..: . .: NP_037 MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPG 10 20 30 40 50 670 680 690 700 pF1KB3 --PEVIKIQNKPE--KKPGTPLPPPAT---SPSSPRPLSPVPHVNN--------VVNA-- : . .: . :::: : :: . :::: .::: . ::.. NP_037 AWPTAPLAAPRPSGLEPPGTPGPGPALPLGAASSPRN---APHVRGTRRSAGTRVVQTRK 60 70 80 90 100 110 710 720 730 740 750 pF1KB3 --PL----SINIPRFYFPEGLPDTCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCG :: : .:: ::::.: :. : . ..:.::..: . ...: . .:: .::.:: NP_037 EEPLPPATSQSIPTFYFPRGRPQDSVNVDAVISKIESTFARFPHERATMDDMGLVAKACG 120 130 140 150 160 170 760 770 780 790 800 810 pF1KB3 CPLYWKAPMFRAAGGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQED ::::::.:.: .::::.:: :....:.:::::.:.: ::::.::. :: .:.:. : ::: NP_037 CPLYWKGPLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQED 180 190 200 210 220 230 820 830 840 850 860 870 pF1KB3 FIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQ :.:.:::::.:::::.:::.: ::::::::::::::::.:::::::.:: .:.:.:.::: NP_037 FVPFLQDVVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQ 240 250 260 270 280 290 880 890 900 910 920 930 pF1KB3 TLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIE ..:::::: ::::.:..:::::::::::::::::::::: :. ::.:.::.: :...:. NP_037 NVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMID 300 310 320 330 340 350 940 950 960 970 980 990 pF1KB3 RIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYEL ::::::::::. .::::..:::::::::::::::..::::::::::::.::::.:::.:: NP_037 RIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFEL 360 370 380 390 400 410 1000 1010 1020 1030 1040 1050 pF1KB3 EYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFN ::::::::.:...:.:: :::.: :::::::::: ..:::::.:::::..:..:.::::: NP_037 EYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFN 420 430 440 450 460 470 1060 1070 1080 1090 1100 1110 pF1KB3 LEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETD .::::::::.. ... .: .. ::: :::...:::::. :::::.: ...::: NP_037 IEKYLDHEQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETAGEPWEDGFEAELSP 480 490 500 510 520 530 1120 1130 1140 1150 pF1KB3 EPASPSEFGNKSNKILSASLPEKCGKLQSVDEE NP_037 VEQKLSALRSPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL 540 550 560 570 >>XP_011544479 (OMIM: 300339) PREDICTED: serine/threonin (565 aa) initn: 2016 init1: 1968 opt: 1971 Z-score: 1463.4 bits: 281.7 E(85289): 9e-75 Smith-Waterman score: 2005; 58.3% identity (80.5% similar) in 503 aa overlap (632-1110:27-526) 610 620 630 640 650 660 pF1KB3 AQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT- :.: :. : . ..: . .: XP_011 MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPG 10 20 30 40 50 670 680 690 700 pF1KB3 --PEVIKIQNKPE--KKPGTPLPPPAT---SPSSPRPLSPVPHVNN--------VVNA-- : . .: . :::: : :: . :::: .::: . ::.. XP_011 AWPTAPLAAPRPSGLEPPGTPGPGPALPLGAASSPRN---APHVRGTRRSAGTRVVQTRK 60 70 80 90 100 110 710 720 730 740 750 pF1KB3 --PL----SINIPRFYFPEGLPDTCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCG :: : .:: ::::.: :. : . ..:.::..: . ...: . .:: .::.:: XP_011 EEPLPPATSQSIPTFYFPRGRPQDSVNVDAVISKIESTFARFPHERATMDDMGLVAKACG 120 130 140 150 160 170 760 770 780 790 800 810 pF1KB3 CPLYWKAPMFRAAGGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQED ::::::.:.: .::::.:: :....:.:::::.:.: ::::.::. :: .:.:. : ::: XP_011 CPLYWKGPLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQED 180 190 200 210 220 230 820 830 840 850 860 870 pF1KB3 FIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQ :.:.:::::.:::::.:::.: ::::::::::::::::.:::::::.:: .:.:.:.::: XP_011 FVPFLQDVVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQ 240 250 260 270 280 290 880 890 900 910 920 930 pF1KB3 TLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIE ..:::::: ::::.:..:::::::::::::::::::::: :. ::.:.::.: :...:. XP_011 NVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMID 300 310 320 330 340 350 940 950 960 970 980 990 pF1KB3 RIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYEL ::::::::::. .::::..:::::::::::::::..::::::::::::.::::.:::.:: XP_011 RIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFEL 360 370 380 390 400 410 1000 1010 1020 1030 1040 1050 pF1KB3 EYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFN ::::::::.:...:.:: :::.: :::::::::: ..:::::.:::::..:..:.::::: XP_011 EYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFN 420 430 440 450 460 470 1060 1070 1080 1090 1100 1110 pF1KB3 LEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETD .::::::::.. ... .: .. ::: :::...:::::. :::::.: ...: XP_011 IEKYLDHEQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETAGEPWEDGDGVSPCC 480 490 500 510 520 530 1120 1130 1140 1150 pF1KB3 EPASPSEFGNKSNKILSASLPEKCGKLQSVDEE XP_011 PGWSWMPELEGSPRLGPPTCRNYRCEPLPSLE 540 550 560 >>XP_011543932 (OMIM: 300339) PREDICTED: serine/threonin (565 aa) initn: 2016 init1: 1968 opt: 1971 Z-score: 1463.4 bits: 281.7 E(85289): 9e-75 Smith-Waterman score: 2005; 58.3% identity (80.5% similar) in 503 aa overlap (632-1110:27-526) 610 620 630 640 650 660 pF1KB3 AQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT- :.: :. : . ..: . .: XP_011 MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPG 10 20 30 40 50 670 680 690 700 pF1KB3 --PEVIKIQNKPE--KKPGTPLPPPAT---SPSSPRPLSPVPHVNN--------VVNA-- : . .: . :::: : :: . :::: .::: . ::.. XP_011 AWPTAPLAAPRPSGLEPPGTPGPGPALPLGAASSPRN---APHVRGTRRSAGTRVVQTRK 60 70 80 90 100 110 710 720 730 740 750 pF1KB3 --PL----SINIPRFYFPEGLPDTCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCG :: : .:: ::::.: :. : . ..:.::..: . ...: . .:: .::.:: XP_011 EEPLPPATSQSIPTFYFPRGRPQDSVNVDAVISKIESTFARFPHERATMDDMGLVAKACG 120 130 140 150 160 170 760 770 780 790 800 810 pF1KB3 CPLYWKAPMFRAAGGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQED ::::::.:.: .::::.:: :....:.:::::.:.: ::::.::. :: .:.:. : ::: XP_011 CPLYWKGPLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQED 180 190 200 210 220 230 820 830 840 850 860 870 pF1KB3 FIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQ :.:.:::::.:::::.:::.: ::::::::::::::::.:::::::.:: .:.:.:.::: XP_011 FVPFLQDVVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQ 240 250 260 270 280 290 880 890 900 910 920 930 pF1KB3 TLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIE ..:::::: ::::.:..:::::::::::::::::::::: :. ::.:.::.: :...:. XP_011 NVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMID 300 310 320 330 340 350 940 950 960 970 980 990 pF1KB3 RIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYEL ::::::::::. .::::..:::::::::::::::..::::::::::::.::::.:::.:: XP_011 RIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFEL 360 370 380 390 400 410 1000 1010 1020 1030 1040 1050 pF1KB3 EYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFN ::::::::.:...:.:: :::.: :::::::::: ..:::::.:::::..:..:.::::: XP_011 EYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFN 420 430 440 450 460 470 1060 1070 1080 1090 1100 1110 pF1KB3 LEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETD .::::::::.. ... .: .. ::: :::...:::::. :::::.: ...: XP_011 IEKYLDHEQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETAGEPWEDGDGVSPCC 480 490 500 510 520 530 1120 1130 1140 1150 pF1KB3 EPASPSEFGNKSNKILSASLPEKCGKLQSVDEE XP_011 PGWSWMPELEGSPRLGPPTCRNYRCEPLPSLE 540 550 560 >>XP_016876878 (OMIM: 615902) PREDICTED: serine/threonin (401 aa) initn: 336 init1: 199 opt: 432 Z-score: 332.4 bits: 71.9 E(85289): 8.9e-12 Smith-Waterman score: 432; 24.5% identity (59.3% similar) in 364 aa overlap (729-1087:51-399) 700 710 720 730 740 750 pF1KB3 NVVNAPLSINIPRFYFPEGLPDTCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCG- :.. .: : :: . .. :... : XP_016 KLREESRAVFLQRKSRELLDNEELQNLWFLLDKHQTPPMIGEEAMINYENFLKVGEKAGA 30 40 50 60 70 80 760 770 780 790 800 810 pF1KB3 -CPLYWKAPMF-RAAGGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQ : .. : .: . .. : .. ..:. . . . :. . . : . . :.. XP_016 KCKQFFTAKVFAKLLHTDSYGRISIMQFFNYVMRKVWLHQTRIG--LSLYDVAGQGYLRE 90 100 110 120 130 820 830 840 850 860 870 pF1KB3 EDFIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNF :. . ... : : : :. . :.: :. :.....:. .. .::: .: .: XP_016 SDLENYILELIPTLPQLDGLEKS--FYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSF 140 150 160 170 180 190 880 890 900 910 920 930 pF1KB3 LQTLALLEEEE--DINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYNDQASSS :. : :..:: .: :..:: .: .. .:: ::. ..:. .::::. . .. XP_016 LDDLLELRDEELSKESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTN 200 210 220 230 240 250 940 950 960 970 980 990 pF1KB3 RIIERIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLS ...:.:. .: .:.:.: .. :... :....:....: :. .:... : :. XP_016 VFLDRVFQECLTY------DGEMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGYLN 260 270 280 290 300 310 1000 1010 1020 1030 1040 1050 pF1KB3 MYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYD .. :.::.. : :. : .:. :.:. ...:.::: ::.:.:: .. XP_016 VFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTT 320 330 340 350 360 370 1060 1070 1080 1090 1100 1110 pF1KB3 TFFNLEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQFQEGFED ...:. . .:.:. . : ::. . .: : XP_016 ILIDLNGFWTYENREAL-----VANDSENSADLDDT 380 390 400 1120 1130 1140 1150 pF1KB3 YETDEPASPSEFGNKSNKILSASLPEKCGKLQSVDEE 1150 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:11:59 2016 done: Thu Nov 3 12:12:02 2016 Total Scan time: 17.300 Total Display time: 0.340 Function used was FASTA [36.3.4 Apr, 2011]