FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3046, 1507 aa 1>>>pF1KB3046 1507 - 1507 aa - 1507 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0292+/-0.00141; mu= 19.4695+/- 0.084 mean_var=72.7981+/-14.880, 0's: 0 Z-trim(98.5): 37 B-trim: 0 in 0/48 Lambda= 0.150319 statistics sampled from 5373 (5391) to 5373 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.499), E-opt: 0.2 (0.166), width: 16 Scan time: 5.400 The best scores are: opt bits E(32554) CCDS46505.1 CPS1 gene_id:1373|Hs108|chr2 (1506) 9830 2142.5 0 CCDS2393.1 CPS1 gene_id:1373|Hs108|chr2 (1500) 9802 2136.5 0 CCDS46506.1 CPS1 gene_id:1373|Hs108|chr2 (1049) 6855 1497.3 0 CCDS1742.1 CAD gene_id:790|Hs108|chr2 (2225) 3231 711.5 7.2e-204 CCDS77396.1 CAD gene_id:790|Hs108|chr2 (2162) 2170 481.4 1.3e-134 >>CCDS46505.1 CPS1 gene_id:1373|Hs108|chr2 (1506 aa) initn: 9813 init1: 9813 opt: 9830 Z-score: 11510.6 bits: 2142.5 E(32554): 0 Smith-Waterman score: 9830; 99.9% identity (99.9% similar) in 1507 aa overlap (1-1507:1-1506) 10 20 30 40 50 60 pF1KB3 MPQIIFKMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG ::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MPQII-KMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB3 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNALPAGWKPLF ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: CCDS46 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLF 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB3 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB3 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB3 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB3 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB3 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB3 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB3 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI 720 730 740 750 760 770 790 800 810 820 830 840 pF1KB3 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW 780 790 800 810 820 830 850 860 870 880 890 900 pF1KB3 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG 840 850 860 870 880 890 910 920 930 940 950 960 pF1KB3 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KB3 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KB3 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KB3 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KB3 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 1250 1260 pF1KB3 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV 1200 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 1320 pF1KB3 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF 1260 1270 1280 1290 1300 1310 1330 1340 1350 1360 1370 1380 pF1KB3 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR 1320 1330 1340 1350 1360 1370 1390 1400 1410 1420 1430 1440 pF1KB3 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID 1380 1390 1400 1410 1420 1430 1450 1460 1470 1480 1490 1500 pF1KB3 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ 1440 1450 1460 1470 1480 1490 pF1KB3 YSAGKAA ::::::: CCDS46 YSAGKAA 1500 >>CCDS2393.1 CPS1 gene_id:1373|Hs108|chr2 (1500 aa) initn: 9802 init1: 9802 opt: 9802 Z-score: 11477.8 bits: 2136.5 E(32554): 0 Smith-Waterman score: 9802; 99.9% identity (100.0% similar) in 1500 aa overlap (8-1507:1-1500) 10 20 30 40 50 60 pF1KB3 MPQIIFKMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB3 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNALPAGWKPLF ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: CCDS23 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLF 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB3 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB3 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB3 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB3 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB3 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB3 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB3 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI 720 730 740 750 760 770 790 800 810 820 830 840 pF1KB3 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW 780 790 800 810 820 830 850 860 870 880 890 900 pF1KB3 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG 840 850 860 870 880 890 910 920 930 940 950 960 pF1KB3 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KB3 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KB3 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KB3 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KB3 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 1250 1260 pF1KB3 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV 1200 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 1320 pF1KB3 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF 1260 1270 1280 1290 1300 1310 1330 1340 1350 1360 1370 1380 pF1KB3 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR 1320 1330 1340 1350 1360 1370 1390 1400 1410 1420 1430 1440 pF1KB3 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID 1380 1390 1400 1410 1420 1430 1450 1460 1470 1480 1490 1500 pF1KB3 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ 1440 1450 1460 1470 1480 1490 pF1KB3 YSAGKAA ::::::: CCDS23 YSAGKAA 1500 >>CCDS46506.1 CPS1 gene_id:1373|Hs108|chr2 (1049 aa) initn: 6855 init1: 6855 opt: 6855 Z-score: 8026.3 bits: 1497.3 E(32554): 0 Smith-Waterman score: 6855; 100.0% identity (100.0% similar) in 1049 aa overlap (459-1507:1-1049) 430 440 450 460 470 480 pF1KB3 VSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADT :::::::::::::::::::::::::::::: CCDS46 MKEENVKTVLMNPNIASVQTNEVGLKQADT 10 20 30 490 500 510 520 530 540 pF1KB3 VYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESI 40 50 60 70 80 90 550 560 570 580 590 600 pF1KB3 MATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICP 100 110 120 130 140 150 610 620 630 640 650 660 pF1KB3 NRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 NRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTG 160 170 180 190 200 210 670 680 690 700 710 720 pF1KB3 DSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSR 220 230 240 250 260 270 730 740 750 760 770 780 pF1KB3 SSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRF 280 290 300 310 320 330 790 800 810 820 830 840 pF1KB3 HGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 HGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRK 340 350 360 370 380 390 850 860 870 880 890 900 pF1KB3 ELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTE 400 410 420 430 440 450 910 920 930 940 950 960 pF1KB3 ETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVT 460 470 480 490 500 510 970 980 990 1000 1010 1020 pF1KB3 YNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 YNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVS 520 530 540 550 560 570 1030 1040 1050 1060 1070 1080 pF1KB3 TDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPL 580 590 600 610 620 630 1090 1100 1110 1120 1130 1140 pF1KB3 QIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMNV 640 650 660 670 680 690 1150 1160 1170 1180 1190 1200 pF1KB3 VFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGV 700 710 720 730 740 750 1210 1220 1230 1240 1250 1260 pF1KB3 HSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 HSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRAS 760 770 780 790 800 810 1270 1280 1290 1300 1310 1320 pF1KB3 RSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDA 820 830 840 850 860 870 1330 1340 1350 1360 1370 1380 pF1KB3 DPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQL 880 890 900 910 920 930 1390 1400 1410 1420 1430 1440 pF1KB3 HNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 HNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNN 940 950 960 970 980 990 1450 1460 1470 1480 1490 1500 pF1KB3 NTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGKAA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 NTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGKAA 1000 1010 1020 1030 1040 >>CCDS1742.1 CAD gene_id:790|Hs108|chr2 (2225 aa) initn: 4206 init1: 1545 opt: 3231 Z-score: 3773.6 bits: 711.5 E(32554): 7.2e-204 Smith-Waterman score: 4842; 51.4% identity (77.5% similar) in 1460 aa overlap (53-1484:2-1440) 30 40 50 60 70 80 pF1KB3 TGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNT : .:::::. ..: :: :.::::::.: CCDS17 MAALVLEDGSVLRGQPFGAAVSTAGEVVFQT 10 20 30 90 100 110 120 130 140 pF1KB3 GLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLD :. :::::.:::.::.:::... :.::: : : .::.:: :..::.::.:..:.: . CCDS17 GMVGYPEALTDPSYKAQILVLTYPLIGNYGIPPDE-MDEFGLCKWFESSGIHVAALVVGE 40 50 60 70 80 90 150 160 170 180 190 pF1KB3 YSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEG-QP--VDF .:: ::..: .:::.. .:.. ::::: ::: .:..:..:::. .: .: . : CCDS17 CCPTPSHWSATRTLHEWLQQHGIPGLQGVDTRELTKKLREQGSLLGKLVQNGTEPSSLPF 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB3 VDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFT .::: . :. ::: : .:.. :. ...:.:::.: : :: : .::::: .:::.: . CCDS17 LDPNARPLVPEVSIKTPRVFNTGGAPRILALDCGLKYNQIRCLCQRGAEVTVVPWDHALD 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB3 KMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMS ..::.:.....:::.:: ..... ..: .:.::: :. . .:: ::::::: CCDS17 SQEYEGLFLSNGPGDPASYPSVVSTLSRVLSEPNPRPVFGICLGHQLLALAIGAKTYKMR 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB3 MANRGQNQPVLNITNKQAFITAQNHGYALD-NALPAGWKPLFVNVNDQTNEGIMHESKPF ..:::.::: : . . . :.:.::::.:.. ..::: : :::.:.:: .::::.:.: :: CCDS17 YGNRGHNQPCLLVGSGRCFLTSQNHGFAVETDSLPADWAPLFTNANDGSNEGIVHNSLPF 280 290 300 310 320 330 380 390 400 410 420 pF1KB3 FAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATT---------ITSVLPKPALVASRVEV :.:::::: :: : : ::: :. .:.. : . .: : :.. . . CCDS17 FSVQFHPEHQAGPSDMELLFDIFLETVKEATAGNPGGQTVRERLTERLCPPGIPTPGSGL 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB3 S---KVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQA :::::::::::::::::::::::::.::.::::..:.:.:::::.:::.. :: : CCDS17 PPPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQ-GL--A 400 410 420 430 440 490 500 510 520 530 540 pF1KB3 DTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVE : ::::::::..::.::. :.:::..: .:::::::::::: : ::: .:::.:::: :: CCDS17 DKVYFLPITPHYVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVE 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB3 SIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGI .: ::::. :. .. ::.:..::: :..:.:.: ::. .::::..:.:.::::::::. CCDS17 TIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGF 510 520 530 540 550 560 610 620 630 640 650 660 pF1KB3 CPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVH ::: : : . ::: :.:.::.::. ::::::::::::: ::::::::::.: .:.: CCDS17 ASNREELSALVAPAFAHTSQVLVDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIH 570 580 590 600 610 620 670 680 690 700 710 720 pF1KB3 TGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARL ::.:.::::.:::.. :.:.::.:.:.:..:::::::::.:.::.: : .: :::::::: CCDS17 TGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARL 630 640 650 660 670 680 730 740 750 760 770 780 pF1KB3 SRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLD ::::::::::::::::..:::.::::::::..: :.: :.: ::::.:: :.:::::::. CCDS17 SRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGGTAA-FEPSVDYCVVKIPRWDLS 690 700 710 720 730 740 790 800 810 820 830 840 pF1KB3 RFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRL-PMNKEWPSNLD .: .:..::: ::::::::.:::.:::.::::::: . :: . :.. : CCDS17 KFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMVDENCVGFDHTVKPVS-------D 750 760 770 780 790 850 860 870 880 890 900 pF1KB3 LRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSES . :: :.. ::...: :. ..:.:.. .:: ::.:::..:. :. . :. .. CCDS17 M--ELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRMKRIIAHAQLLEQHRGQP 800 810 820 830 840 850 910 920 930 940 950 960 pF1KB3 MTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYL . . :..:: .:::::::. . :: .:.:: . .: : ::::::.:::.:. :::: CCDS17 LPPDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVKQIDTVAAEWPAQTNYL 860 870 880 890 900 910 970 980 990 1000 1010 1020 pF1KB3 YVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPE :.:: : ::..: ..::: : :.::::::::::::. :. ::..: ::..:: ::: CCDS17 YLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPE 920 930 940 950 960 970 1030 1040 1050 1060 1070 1080 pF1KB3 TVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGT :::::.: ::.:::.:.:.: ..:::. : : :.:.:::.:::.:. :... ...:: CCDS17 TVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLGT 980 990 1000 1010 1020 1030 1090 1100 1110 1120 1130 1140 pF1KB3 SPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSA :: :: ::.: :: .:: . ..: :. .. :. : .: ..: :::..::::::::.: CCDS17 SPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTVGYPCVVRPSYVLSGAA 1040 1050 1060 1070 1080 1090 1150 1160 1170 1180 1190 1200 pF1KB3 MNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVED :::.... ....:: :. ::.:::::..::.. :.:...:::..:: : . :::::::. CCDS17 MNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVASDGVVAAIAISEHVEN 1100 1110 1120 1130 1140 1150 1210 1220 1230 1240 1250 1260 pF1KB3 AGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNL ::::::::::. : : :. ..:..: .. ... . ..::::.:...: ... :::::. CCDS17 AGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNV 1160 1170 1180 1190 1200 1210 1270 1280 1290 1300 1310 1320 pF1KB3 RASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRL :.::::::::::::::.. .::.:..::.:. : : . :..:.:.::. :: CCDS17 RVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMT------GSGVVGVKVPQFSFSRL 1220 1230 1240 1250 1260 1270 1330 1340 1350 1360 1370 1380 pF1KB3 RDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR--FLG :: .: ::.:::::: :::. :.::::::::::::.:.::. : :.. . .: CCDS17 AGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIG-SYKNKSELLP 1280 1290 1300 1310 1320 1330 1390 1400 1410 1420 1430 1440 pF1KB3 VAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQE---GQNPSLSSIRKLIRDGSID ... :.. :..:.:. .:.:. . ..: .: : : .: :. : :: . . . ... CCDS17 TVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSILEQLAEKNFE 1340 1350 1360 1370 1380 1390 1450 1460 1470 1480 1490 pF1KB3 LVINLPNNN------TKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKS ::::: . ..:: .: :: :.: ..::. ... ::::.::. CCDS17 LVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQIGPAPPLK 1400 1410 1420 1430 1440 1450 1500 pF1KB3 LFHYRQYSAGKAA CCDS17 VHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMVCAMPNTRPPI 1460 1470 1480 1490 1500 1510 >>CCDS77396.1 CAD gene_id:790|Hs108|chr2 (2162 aa) initn: 3921 init1: 1545 opt: 2170 Z-score: 2530.3 bits: 481.4 E(32554): 1.3e-134 Smith-Waterman score: 4403; 48.7% identity (73.4% similar) in 1460 aa overlap (53-1484:2-1377) 30 40 50 60 70 80 pF1KB3 TGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNT : .:::::. ..: :: :.::::::.: CCDS77 MAALVLEDGSVLRGQPFGAAVSTAGEVVFQT 10 20 30 90 100 110 120 130 140 pF1KB3 GLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLD :. :::::.:::.::.:::... :.::: : : .::.:: :..::.::.:..:.: . CCDS77 GMVGYPEALTDPSYKAQILVLTYPLIGNYGIPPDE-MDEFGLCKWFESSGIHVAALVVGE 40 50 60 70 80 90 150 160 170 180 190 pF1KB3 YSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEG-QP--VDF .:: ::..: .:::.. .:.. ::::: ::: .:..:..:::. .: .: . : CCDS77 CCPTPSHWSATRTLHEWLQQHGIPGLQGVDTRELTKKLREQGSLLGKLVQNGTEPSSLPF 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB3 VDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFT .::: . :. ::: : .:.. :. ...:.:::.: : :: : .::::: .:::.: . CCDS77 LDPNARPLVPEVSIKTPRVFNTGGAPRILALDCGLKYNQIRCLCQRGAEVTVVPWDHALD 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB3 KMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMS ..::.:.....:::.:: ..... ..: .:.::: :. . .:: ::::::: CCDS77 SQEYEGLFLSNGPGDPASYPSVVSTLSRVLSEPNPRPVFGICLGHQLLALAIGAKTYKMR 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB3 MANRGQNQPVLNITNKQAFITAQNHGYALD-NALPAGWKPLFVNVNDQTNEGIMHESKPF ..:::.::: : . . . :.:.::::.:.. ..::: : :::.:.:: .::::.:.: :: CCDS77 YGNRGHNQPCLLVGSGRCFLTSQNHGFAVETDSLPADWAPLFTNANDGSNEGIVHNSLPF 280 290 300 310 320 330 380 390 400 410 420 pF1KB3 FAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATT---------ITSVLPKPALVASRVEV :.:::::: :: : : ::: :. .:.. : . .: : :.. . . CCDS77 FSVQFHPEHQAGPSDMELLFDIFLETVKEATAGNPGGQTVRERLTERLCPPGIPTPGSGL 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB3 S---KVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQA :::::::::::::::::::::::::.::.::::..:.:.:::::.:::.. :: : CCDS77 PPPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQ-GL--A 400 410 420 430 440 490 500 510 520 530 540 pF1KB3 DTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVE : ::::::::..::.::. :.:::..: .:::::::::::: : ::: .:::.:::: :: CCDS77 DKVYFLPITPHYVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVE 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB3 SIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGI .: ::::. :. .. ::.:..::: :..:.:.: ::. .::::..:.:.::::::::. CCDS77 TIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGF 510 520 530 540 550 560 610 620 630 640 650 660 pF1KB3 CPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVH ::: : : . ::: :.:.::.::. ::::::::::::: :::: CCDS77 ASNREELSALVAPAFAHTSQVLVDKSLKGWKEIEYEVVRDAYGNCVT------------- 570 580 590 600 610 670 680 690 700 710 720 pF1KB3 TGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARL : :::::::: CCDS77 --------------------------------------------------YYIIEVNARL 620 730 740 750 760 770 780 pF1KB3 SRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLD ::::::::::::::::..:::.::::::::..: :.: :.: ::::.:: :.:::::::. CCDS77 SRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGGTAA-FEPSVDYCVVKIPRWDLS 630 640 650 660 670 680 790 800 810 820 830 840 pF1KB3 RFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRL-PMNKEWPSNLD .: .:..::: ::::::::.:::.:::.::::::: . :: . :.. : CCDS77 KFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMVDENCVGFDHTVKPVS-------D 690 700 710 720 730 850 860 870 880 890 900 pF1KB3 LRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSES . :: :.. ::...: :. ..:.:.. .:: ::.:::..:. :. . :. .. CCDS77 M--ELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRMKRIIAHAQLLEQHRGQP 740 750 760 770 780 790 910 920 930 940 950 960 pF1KB3 MTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYL . . :..:: .:::::::. . :: .:.:: . .: : ::::::.:::.:. :::: CCDS77 LPPDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVKQIDTVAAEWPAQTNYL 800 810 820 830 840 850 970 980 990 1000 1010 1020 pF1KB3 YVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPE :.:: : ::..: ..::: : :.::::::::::::. :. ::..: ::..:: ::: CCDS77 YLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPE 860 870 880 890 900 910 1030 1040 1050 1060 1070 1080 pF1KB3 TVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGT :::::.: ::.:::.:.:.: ..:::. : : :.:.:::.:::.:. :... ...:: CCDS77 TVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLGT 920 930 940 950 960 970 1090 1100 1110 1120 1130 1140 pF1KB3 SPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSA :: :: ::.: :: .:: . ..: :. .. :. : .: ..: :::..::::::::.: CCDS77 SPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTVGYPCVVRPSYVLSGAA 980 990 1000 1010 1020 1030 1150 1160 1170 1180 1190 1200 pF1KB3 MNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVED :::.... ....:: :. ::.:::::..::.. :.:...:::..:: : . :::::::. CCDS77 MNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVASDGVVAAIAISEHVEN 1040 1050 1060 1070 1080 1090 1210 1220 1230 1240 1250 1260 pF1KB3 AGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNL ::::::::::. : : :. ..:..: .. ... . ..::::.:...: ... :::::. CCDS77 AGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNV 1100 1110 1120 1130 1140 1150 1270 1280 1290 1300 1310 1320 pF1KB3 RASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRL :.::::::::::::::.. .::.:..::.:. : : . :..:.:.::. :: CCDS77 RVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMT------GSGVVGVKVPQFSFSRL 1160 1170 1180 1190 1200 1330 1340 1350 1360 1370 1380 pF1KB3 RDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR--FLG :: .: ::.:::::: :::. :.::::::::::::.:.::. : :.. . .: CCDS77 AGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIG-SYKNKSELLP 1210 1220 1230 1240 1250 1260 1390 1400 1410 1420 1430 1440 pF1KB3 VAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQE---GQNPSLSSIRKLIRDGSID ... :.. :..:.:. .:.:. . ..: .: : : .: :. : :: . . . ... CCDS77 TVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSILEQLAEKNFE 1270 1280 1290 1300 1310 1320 1450 1460 1470 1480 1490 pF1KB3 LVINLPNNN------TKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKS ::::: . ..:: .: :: :.: ..::. ... ::::.::. CCDS77 LVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQIGPAPPLK 1330 1340 1350 1360 1370 1380 1500 pF1KB3 LFHYRQYSAGKAA CCDS77 VHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMVCAMPNTRPPI 1390 1400 1410 1420 1430 1440 1507 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:35:11 2016 done: Thu Nov 3 20:35:12 2016 Total Scan time: 5.400 Total Display time: 0.450 Function used was FASTA [36.3.4 Apr, 2011]