Result of FASTA (omim) for
pF1KB3046
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3046, 1507 aa
1>>>pF1KB3046 1507 - 1507 aa - 1507 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9642+/-0.000581; mu= 26.1737+/- 0.036
mean_var=76.0530+/-16.120, 0's: 0 Z-trim(106.0): 74 B-trim: 698 in 1/50
Lambda= 0.147067
statistics sampled from 14023 (14097) to 14023 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.491), E-opt: 0.2 (0.165), width: 16
Scan time: 17.000
The best scores are: opt bits E(85289)
NP_001116105 (OMIM: 237300,608307,615371) carbamoy (1506) 9830 2096.9 0
XP_011508942 (OMIM: 237300,608307,615371) PREDICTE (1511) 9823 2095.5 0
NP_001866 (OMIM: 237300,608307,615371) carbamoyl-p (1500) 9802 2091.0 0
XP_011508945 (OMIM: 237300,608307,615371) PREDICTE (1500) 9802 2091.0 0
XP_011508943 (OMIM: 237300,608307,615371) PREDICTE (1500) 9802 2091.0 0
XP_011508944 (OMIM: 237300,608307,615371) PREDICTE (1500) 9802 2091.0 0
XP_011508946 (OMIM: 237300,608307,615371) PREDICTE (1500) 9802 2091.0 0
NP_001116106 (OMIM: 237300,608307,615371) carbamoy (1049) 6855 1465.6 0
NP_004332 (OMIM: 114010,616457) CAD protein isofor (2225) 3231 697.0 4.5e-199
XP_005264612 (OMIM: 114010,616457) PREDICTED: CAD (2242) 3231 697.0 4.5e-199
NP_001293008 (OMIM: 114010,616457) CAD protein iso (2162) 2170 471.8 2.5e-131
XP_006712164 (OMIM: 114010,616457) PREDICTED: CAD (2179) 2170 471.8 2.6e-131
XP_005257324 (OMIM: 200350,613933) PREDICTED: acet (2268) 232 60.7 1.6e-07
XP_011523006 (OMIM: 200350,613933) PREDICTED: acet (2268) 232 60.7 1.6e-07
NP_942135 (OMIM: 200350,613933) acetyl-CoA carboxy (2268) 232 60.7 1.6e-07
NP_942134 (OMIM: 200350,613933) acetyl-CoA carboxy (2288) 232 60.7 1.6e-07
NP_942133 (OMIM: 200350,613933) acetyl-CoA carboxy (2346) 232 60.7 1.6e-07
XP_011523005 (OMIM: 200350,613933) PREDICTED: acet (2346) 232 60.7 1.6e-07
XP_016880044 (OMIM: 200350,613933) PREDICTED: acet (2346) 232 60.7 1.6e-07
NP_942136 (OMIM: 200350,613933) acetyl-CoA carboxy (2346) 232 60.7 1.6e-07
XP_011523003 (OMIM: 200350,613933) PREDICTED: acet (2353) 232 60.7 1.6e-07
XP_006721916 (OMIM: 200350,613933) PREDICTED: acet (2375) 232 60.7 1.6e-07
XP_016880043 (OMIM: 200350,613933) PREDICTED: acet (2383) 232 60.7 1.7e-07
NP_942131 (OMIM: 200350,613933) acetyl-CoA carboxy (2383) 232 60.7 1.7e-07
XP_016880042 (OMIM: 200350,613933) PREDICTED: acet (2391) 232 60.7 1.7e-07
XP_016876105 (OMIM: 232000,606054) PREDICTED: prop ( 551) 218 57.1 4.4e-07
XP_016876104 (OMIM: 232000,606054) PREDICTED: prop ( 624) 218 57.2 4.9e-07
XP_005254116 (OMIM: 232000,606054) PREDICTED: prop ( 640) 218 57.2 5e-07
XP_016876103 (OMIM: 232000,606054) PREDICTED: prop ( 655) 218 57.2 5e-07
XP_016876102 (OMIM: 232000,606054) PREDICTED: prop ( 669) 218 57.2 5.1e-07
NP_001171475 (OMIM: 232000,606054) propionyl-CoA c ( 681) 218 57.2 5.2e-07
XP_016876101 (OMIM: 232000,606054) PREDICTED: prop ( 681) 218 57.2 5.2e-07
XP_016876100 (OMIM: 232000,606054) PREDICTED: prop ( 683) 218 57.2 5.2e-07
XP_016876098 (OMIM: 232000,606054) PREDICTED: prop ( 695) 218 57.2 5.3e-07
XP_011519395 (OMIM: 232000,606054) PREDICTED: prop ( 699) 218 57.2 5.3e-07
NP_001121164 (OMIM: 232000,606054) propionyl-CoA c ( 702) 218 57.2 5.3e-07
XP_016876097 (OMIM: 232000,606054) PREDICTED: prop ( 710) 218 57.2 5.3e-07
XP_016876096 (OMIM: 232000,606054) PREDICTED: prop ( 711) 218 57.2 5.4e-07
XP_016876095 (OMIM: 232000,606054) PREDICTED: prop ( 718) 218 57.2 5.4e-07
NP_000273 (OMIM: 232000,606054) propionyl-CoA carb ( 728) 218 57.3 5.4e-07
XP_016876094 (OMIM: 232000,606054) PREDICTED: prop ( 744) 218 57.3 5.5e-07
NP_000911 (OMIM: 266150,608786) pyruvate carboxyla (1178) 214 56.6 1.4e-06
XP_006718641 (OMIM: 266150,608786) PREDICTED: pyru (1178) 214 56.6 1.4e-06
XP_016873357 (OMIM: 266150,608786) PREDICTED: pyru (1178) 214 56.6 1.4e-06
XP_016873361 (OMIM: 266150,608786) PREDICTED: pyru (1178) 214 56.6 1.4e-06
XP_011543388 (OMIM: 266150,608786) PREDICTED: pyru (1178) 214 56.6 1.4e-06
XP_005274089 (OMIM: 266150,608786) PREDICTED: pyru (1178) 214 56.6 1.4e-06
NP_071504 (OMIM: 266150,608786) pyruvate carboxyla (1178) 214 56.6 1.4e-06
NP_001035806 (OMIM: 266150,608786) pyruvate carbox (1178) 214 56.6 1.4e-06
XP_016873358 (OMIM: 266150,608786) PREDICTED: pyru (1178) 214 56.6 1.4e-06
>>NP_001116105 (OMIM: 237300,608307,615371) carbamoyl-ph (1506 aa)
initn: 9813 init1: 9813 opt: 9830 Z-score: 11264.2 bits: 2096.9 E(85289): 0
Smith-Waterman score: 9830; 99.9% identity (99.9% similar) in 1507 aa overlap (1-1507:1-1506)
10 20 30 40 50 60
pF1KB3 MPQIIFKMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPQII-KMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNALPAGWKPLF
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
NP_001 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLF
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB3 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB3 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB3 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB3 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB3 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB3 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB3 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KB3 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KB3 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KB3 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ
1440 1450 1460 1470 1480 1490
pF1KB3 YSAGKAA
:::::::
NP_001 YSAGKAA
1500
>>XP_011508942 (OMIM: 237300,608307,615371) PREDICTED: c (1511 aa)
initn: 9813 init1: 9813 opt: 9823 Z-score: 11256.2 bits: 2095.5 E(85289): 0
Smith-Waterman score: 9823; 99.9% identity (99.9% similar) in 1506 aa overlap (2-1507:7-1511)
10 20 30 40 50
pF1KB3 MPQIIFKMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHI
:::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKMLEEPQII-KMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHI
10 20 30 40 50
60 70 80 90 100 110
pF1KB3 VLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 TTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRM
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB3 LTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB3 NNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB3 PLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNALPAG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_011 PLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAG
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB3 WKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITS
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB3 VLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIAS
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB3 VQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKE
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB3 YGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRS
540 550 560 570 580 590
600 610 620 630 640 650
pF1KB3 AYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVC
600 610 620 630 640 650
660 670 680 690 700 710
pF1KB3 NMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSM
660 670 680 690 700 710
720 730 740 750 760 770
pF1KB3 EYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDY
720 730 740 750 760 770
780 790 800 810 820 830
pF1KB3 MVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLP
780 790 800 810 820 830
840 850 860 870 880 890
pF1KB3 MNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNME
840 850 860 870 880 890
900 910 920 930 940 950
pF1KB3 KTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLA
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KB3 AEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGK
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
pF1KB3 KTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPL
1020 1030 1040 1050 1060 1070
1080 1090 1100 1110 1120 1130
pF1KB3 YKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLL
1080 1090 1100 1110 1120 1130
1140 1150 1160 1170 1180 1190
pF1KB3 RPSYVLSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPSYVLSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVI
1140 1150 1160 1170 1180 1190
1200 1210 1220 1230 1240 1250
pF1KB3 SHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKG
1200 1210 1220 1230 1240 1250
1260 1270 1280 1290 1300 1310
pF1KB3 NDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAI
1260 1270 1280 1290 1300 1310
1320 1330 1340 1350 1360 1370
pF1KB3 KAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQ
1320 1330 1340 1350 1360 1370
1380 1390 1400 1410 1420 1430
pF1KB3 SFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIR
1380 1390 1400 1410 1420 1430
1440 1450 1460 1470 1480 1490
pF1KB3 DGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSL
1440 1450 1460 1470 1480 1490
1500
pF1KB3 FHYRQYSAGKAA
::::::::::::
XP_011 FHYRQYSAGKAA
1500 1510
>>NP_001866 (OMIM: 237300,608307,615371) carbamoyl-phosp (1500 aa)
initn: 9802 init1: 9802 opt: 9802 Z-score: 11232.1 bits: 2091.0 E(85289): 0
Smith-Waterman score: 9802; 99.9% identity (100.0% similar) in 1500 aa overlap (8-1507:1-1500)
10 20 30 40 50 60
pF1KB3 MPQIIFKMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNALPAGWKPLF
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
NP_001 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLF
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB3 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB3 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB3 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB3 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB3 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB3 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB3 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KB3 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KB3 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KB3 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ
1440 1450 1460 1470 1480 1490
pF1KB3 YSAGKAA
:::::::
NP_001 YSAGKAA
1500
>>XP_011508945 (OMIM: 237300,608307,615371) PREDICTED: c (1500 aa)
initn: 9802 init1: 9802 opt: 9802 Z-score: 11232.1 bits: 2091.0 E(85289): 0
Smith-Waterman score: 9802; 99.9% identity (100.0% similar) in 1500 aa overlap (8-1507:1-1500)
10 20 30 40 50 60
pF1KB3 MPQIIFKMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNALPAGWKPLF
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_011 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLF
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB3 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB3 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB3 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB3 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB3 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB3 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB3 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KB3 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KB3 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KB3 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ
1440 1450 1460 1470 1480 1490
pF1KB3 YSAGKAA
:::::::
XP_011 YSAGKAA
1500
>>XP_011508943 (OMIM: 237300,608307,615371) PREDICTED: c (1500 aa)
initn: 9802 init1: 9802 opt: 9802 Z-score: 11232.1 bits: 2091.0 E(85289): 0
Smith-Waterman score: 9802; 99.9% identity (100.0% similar) in 1500 aa overlap (8-1507:1-1500)
10 20 30 40 50 60
pF1KB3 MPQIIFKMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNALPAGWKPLF
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_011 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLF
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB3 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB3 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB3 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB3 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB3 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB3 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB3 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KB3 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KB3 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KB3 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ
1440 1450 1460 1470 1480 1490
pF1KB3 YSAGKAA
:::::::
XP_011 YSAGKAA
1500
>>XP_011508944 (OMIM: 237300,608307,615371) PREDICTED: c (1500 aa)
initn: 9802 init1: 9802 opt: 9802 Z-score: 11232.1 bits: 2091.0 E(85289): 0
Smith-Waterman score: 9802; 99.9% identity (100.0% similar) in 1500 aa overlap (8-1507:1-1500)
10 20 30 40 50 60
pF1KB3 MPQIIFKMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNALPAGWKPLF
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_011 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLF
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB3 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB3 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB3 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB3 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB3 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB3 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB3 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KB3 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KB3 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KB3 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ
1440 1450 1460 1470 1480 1490
pF1KB3 YSAGKAA
:::::::
XP_011 YSAGKAA
1500
>>XP_011508946 (OMIM: 237300,608307,615371) PREDICTED: c (1500 aa)
initn: 9802 init1: 9802 opt: 9802 Z-score: 11232.1 bits: 2091.0 E(85289): 0
Smith-Waterman score: 9802; 99.9% identity (100.0% similar) in 1500 aa overlap (8-1507:1-1500)
10 20 30 40 50 60
pF1KB3 MPQIIFKMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDG
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKII
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNALPAGWKPLF
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_011 STGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLF
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKP
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNE
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKV
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENV
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCII
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKI
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEW
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKG
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB3 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPS
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB3 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB3 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB3 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB3 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB3 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLV
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB3 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMF
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KB3 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KB3 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSID
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KB3 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQ
1440 1450 1460 1470 1480 1490
pF1KB3 YSAGKAA
:::::::
XP_011 YSAGKAA
1500
>>NP_001116106 (OMIM: 237300,608307,615371) carbamoyl-ph (1049 aa)
initn: 6855 init1: 6855 opt: 6855 Z-score: 7854.9 bits: 1465.6 E(85289): 0
Smith-Waterman score: 6855; 100.0% identity (100.0% similar) in 1049 aa overlap (459-1507:1-1049)
430 440 450 460 470 480
pF1KB3 VSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADT
::::::::::::::::::::::::::::::
NP_001 MKEENVKTVLMNPNIASVQTNEVGLKQADT
10 20 30
490 500 510 520 530 540
pF1KB3 VYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESI
40 50 60 70 80 90
550 560 570 580 590 600
pF1KB3 MATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICP
100 110 120 130 140 150
610 620 630 640 650 660
pF1KB3 NRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTG
160 170 180 190 200 210
670 680 690 700 710 720
pF1KB3 DSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSR
220 230 240 250 260 270
730 740 750 760 770 780
pF1KB3 SSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRF
280 290 300 310 320 330
790 800 810 820 830 840
pF1KB3 HGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRK
340 350 360 370 380 390
850 860 870 880 890 900
pF1KB3 ELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTE
400 410 420 430 440 450
910 920 930 940 950 960
pF1KB3 ETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVT
460 470 480 490 500 510
970 980 990 1000 1010 1020
pF1KB3 YNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVS
520 530 540 550 560 570
1030 1040 1050 1060 1070 1080
pF1KB3 TDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPL
580 590 600 610 620 630
1090 1100 1110 1120 1130 1140
pF1KB3 QIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMNV
640 650 660 670 680 690
1150 1160 1170 1180 1190 1200
pF1KB3 VFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGV
700 710 720 730 740 750
1210 1220 1230 1240 1250 1260
pF1KB3 HSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRAS
760 770 780 790 800 810
1270 1280 1290 1300 1310 1320
pF1KB3 RSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDA
820 830 840 850 860 870
1330 1340 1350 1360 1370 1380
pF1KB3 DPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQL
880 890 900 910 920 930
1390 1400 1410 1420 1430 1440
pF1KB3 HNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNN
940 950 960 970 980 990
1450 1460 1470 1480 1490 1500
pF1KB3 NTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGKAA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGKAA
1000 1010 1020 1030 1040
>>NP_004332 (OMIM: 114010,616457) CAD protein isoform 1 (2225 aa)
initn: 4206 init1: 1545 opt: 3231 Z-score: 3695.1 bits: 697.0 E(85289): 4.5e-199
Smith-Waterman score: 4842; 51.4% identity (77.5% similar) in 1460 aa overlap (53-1484:2-1440)
30 40 50 60 70 80
pF1KB3 TGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNT
: .:::::. ..: :: :.::::::.:
NP_004 MAALVLEDGSVLRGQPFGAAVSTAGEVVFQT
10 20 30
90 100 110 120 130 140
pF1KB3 GLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLD
:. :::::.:::.::.:::... :.::: : : .::.:: :..::.::.:..:.: .
NP_004 GMVGYPEALTDPSYKAQILVLTYPLIGNYGIPPDE-MDEFGLCKWFESSGIHVAALVVGE
40 50 60 70 80 90
150 160 170 180 190
pF1KB3 YSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEG-QP--VDF
.:: ::..: .:::.. .:.. ::::: ::: .:..:..:::. .: .: . :
NP_004 CCPTPSHWSATRTLHEWLQQHGIPGLQGVDTRELTKKLREQGSLLGKLVQNGTEPSSLPF
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB3 VDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFT
.::: . :. ::: : .:.. :. ...:.:::.: : :: : .::::: .:::.: .
NP_004 LDPNARPLVPEVSIKTPRVFNTGGAPRILALDCGLKYNQIRCLCQRGAEVTVVPWDHALD
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB3 KMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMS
..::.:.....:::.:: ..... ..: .:.::: :. . .:: :::::::
NP_004 SQEYEGLFLSNGPGDPASYPSVVSTLSRVLSEPNPRPVFGICLGHQLLALAIGAKTYKMR
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB3 MANRGQNQPVLNITNKQAFITAQNHGYALD-NALPAGWKPLFVNVNDQTNEGIMHESKPF
..:::.::: : . . . :.:.::::.:.. ..::: : :::.:.:: .::::.:.: ::
NP_004 YGNRGHNQPCLLVGSGRCFLTSQNHGFAVETDSLPADWAPLFTNANDGSNEGIVHNSLPF
280 290 300 310 320 330
380 390 400 410 420
pF1KB3 FAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATT---------ITSVLPKPALVASRVEV
:.:::::: :: : : ::: :. .:.. : . .: : :.. . .
NP_004 FSVQFHPEHQAGPSDMELLFDIFLETVKEATAGNPGGQTVRERLTERLCPPGIPTPGSGL
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB3 S---KVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQA
:::::::::::::::::::::::::.::.::::..:.:.:::::.:::.. :: :
NP_004 PPPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQ-GL--A
400 410 420 430 440
490 500 510 520 530 540
pF1KB3 DTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVE
: ::::::::..::.::. :.:::..: .:::::::::::: : ::: .:::.:::: ::
NP_004 DKVYFLPITPHYVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVE
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB3 SIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGI
.: ::::. :. .. ::.:..::: :..:.:.: ::. .::::..:.:.::::::::.
NP_004 TIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGF
510 520 530 540 550 560
610 620 630 640 650 660
pF1KB3 CPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVH
::: : : . ::: :.:.::.::. ::::::::::::: ::::::::::.: .:.:
NP_004 ASNREELSALVAPAFAHTSQVLVDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIH
570 580 590 600 610 620
670 680 690 700 710 720
pF1KB3 TGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARL
::.:.::::.:::.. :.:.::.:.:.:..:::::::::.:.::.: : .: ::::::::
NP_004 TGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARL
630 640 650 660 670 680
730 740 750 760 770 780
pF1KB3 SRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLD
::::::::::::::::..:::.::::::::..: :.: :.: ::::.:: :.:::::::.
NP_004 SRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGGTAA-FEPSVDYCVVKIPRWDLS
690 700 710 720 730 740
790 800 810 820 830 840
pF1KB3 RFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRL-PMNKEWPSNLD
.: .:..::: ::::::::.:::.:::.::::::: . :: . :.. :
NP_004 KFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMVDENCVGFDHTVKPVS-------D
750 760 770 780 790
850 860 870 880 890 900
pF1KB3 LRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSES
. :: :.. ::...: :. ..:.:.. .:: ::.:::..:. :. . :. ..
NP_004 M--ELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRMKRIIAHAQLLEQHRGQP
800 810 820 830 840 850
910 920 930 940 950 960
pF1KB3 MTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYL
. . :..:: .:::::::. . :: .:.:: . .: : ::::::.:::.:. ::::
NP_004 LPPDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVKQIDTVAAEWPAQTNYL
860 870 880 890 900 910
970 980 990 1000 1010 1020
pF1KB3 YVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPE
:.:: : ::..: ..::: : :.::::::::::::. :. ::..: ::..:: :::
NP_004 YLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPE
920 930 940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KB3 TVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGT
:::::.: ::.:::.:.:.: ..:::. : : :.:.:::.:::.:. :... ...::
NP_004 TVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLGT
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KB3 SPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSA
:: :: ::.: :: .:: . ..: :. .. :. : .: ..: :::..::::::::.:
NP_004 SPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTVGYPCVVRPSYVLSGAA
1040 1050 1060 1070 1080 1090
1150 1160 1170 1180 1190 1200
pF1KB3 MNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVED
:::.... ....:: :. ::.:::::..::.. :.:...:::..:: : . :::::::.
NP_004 MNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVASDGVVAAIAISEHVEN
1100 1110 1120 1130 1140 1150
1210 1220 1230 1240 1250 1260
pF1KB3 AGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNL
::::::::::. : : :. ..:..: .. ... . ..::::.:...: ... :::::.
NP_004 AGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNV
1160 1170 1180 1190 1200 1210
1270 1280 1290 1300 1310 1320
pF1KB3 RASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRL
:.::::::::::::::.. .::.:..::.:. : : . :..:.:.::. ::
NP_004 RVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMT------GSGVVGVKVPQFSFSRL
1220 1230 1240 1250 1260 1270
1330 1340 1350 1360 1370 1380
pF1KB3 RDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR--FLG
:: .: ::.:::::: :::. :.::::::::::::.:.::. : :.. . .:
NP_004 AGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIG-SYKNKSELLP
1280 1290 1300 1310 1320 1330
1390 1400 1410 1420 1430 1440
pF1KB3 VAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQE---GQNPSLSSIRKLIRDGSID
... :.. :..:.:. .:.:. . ..: .: : : .: :. : :: . . . ...
NP_004 TVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSILEQLAEKNFE
1340 1350 1360 1370 1380 1390
1450 1460 1470 1480 1490
pF1KB3 LVINLPNNN------TKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKS
::::: . ..:: .: :: :.: ..::. ... ::::.::.
NP_004 LVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQIGPAPPLK
1400 1410 1420 1430 1440 1450
1500
pF1KB3 LFHYRQYSAGKAA
NP_004 VHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMVCAMPNTRPPI
1460 1470 1480 1490 1500 1510
>>XP_005264612 (OMIM: 114010,616457) PREDICTED: CAD prot (2242 aa)
initn: 4206 init1: 1545 opt: 3231 Z-score: 3695.0 bits: 697.0 E(85289): 4.5e-199
Smith-Waterman score: 4842; 51.4% identity (77.5% similar) in 1460 aa overlap (53-1484:2-1440)
30 40 50 60 70 80
pF1KB3 TGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNT
: .:::::. ..: :: :.::::::.:
XP_005 MAALVLEDGSVLRGQPFGAAVSTAGEVVFQT
10 20 30
90 100 110 120 130 140
pF1KB3 GLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLD
:. :::::.:::.::.:::... :.::: : : .::.:: :..::.::.:..:.: .
XP_005 GMVGYPEALTDPSYKAQILVLTYPLIGNYGIPPDE-MDEFGLCKWFESSGIHVAALVVGE
40 50 60 70 80 90
150 160 170 180 190
pF1KB3 YSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEG-QP--VDF
.:: ::..: .:::.. .:.. ::::: ::: .:..:..:::. .: .: . :
XP_005 CCPTPSHWSATRTLHEWLQQHGIPGLQGVDTRELTKKLREQGSLLGKLVQNGTEPSSLPF
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB3 VDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFT
.::: . :. ::: : .:.. :. ...:.:::.: : :: : .::::: .:::.: .
XP_005 LDPNARPLVPEVSIKTPRVFNTGGAPRILALDCGLKYNQIRCLCQRGAEVTVVPWDHALD
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB3 KMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMS
..::.:.....:::.:: ..... ..: .:.::: :. . .:: :::::::
XP_005 SQEYEGLFLSNGPGDPASYPSVVSTLSRVLSEPNPRPVFGICLGHQLLALAIGAKTYKMR
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB3 MANRGQNQPVLNITNKQAFITAQNHGYALD-NALPAGWKPLFVNVNDQTNEGIMHESKPF
..:::.::: : . . . :.:.::::.:.. ..::: : :::.:.:: .::::.:.: ::
XP_005 YGNRGHNQPCLLVGSGRCFLTSQNHGFAVETDSLPADWAPLFTNANDGSNEGIVHNSLPF
280 290 300 310 320 330
380 390 400 410 420
pF1KB3 FAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATT---------ITSVLPKPALVASRVEV
:.:::::: :: : : ::: :. .:.. : . .: : :.. . .
XP_005 FSVQFHPEHQAGPSDMELLFDIFLETVKEATAGNPGGQTVRERLTERLCPPGIPTPGSGL
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB3 S---KVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQA
:::::::::::::::::::::::::.::.::::..:.:.:::::.:::.. :: :
XP_005 PPPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQ-GL--A
400 410 420 430 440
490 500 510 520 530 540
pF1KB3 DTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVE
: ::::::::..::.::. :.:::..: .:::::::::::: : ::: .:::.:::: ::
XP_005 DKVYFLPITPHYVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVE
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB3 SIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGI
.: ::::. :. .. ::.:..::: :..:.:.: ::. .::::..:.:.::::::::.
XP_005 TIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGF
510 520 530 540 550 560
610 620 630 640 650 660
pF1KB3 CPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVH
::: : : . ::: :.:.::.::. ::::::::::::: ::::::::::.: .:.:
XP_005 ASNREELSALVAPAFAHTSQVLVDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIH
570 580 590 600 610 620
670 680 690 700 710 720
pF1KB3 TGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARL
::.:.::::.:::.. :.:.::.:.:.:..:::::::::.:.::.: : .: ::::::::
XP_005 TGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARL
630 640 650 660 670 680
730 740 750 760 770 780
pF1KB3 SRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLD
::::::::::::::::..:::.::::::::..: :.: :.: ::::.:: :.:::::::.
XP_005 SRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGGTAA-FEPSVDYCVVKIPRWDLS
690 700 710 720 730 740
790 800 810 820 830 840
pF1KB3 RFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRL-PMNKEWPSNLD
.: .:..::: ::::::::.:::.:::.::::::: . :: . :.. :
XP_005 KFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMVDENCVGFDHTVKPVS-------D
750 760 770 780 790
850 860 870 880 890 900
pF1KB3 LRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSES
. :: :.. ::...: :. ..:.:.. .:: ::.:::..:. :. . :. ..
XP_005 M--ELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRMKRIIAHAQLLEQHRGQP
800 810 820 830 840 850
910 920 930 940 950 960
pF1KB3 MTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYL
. . :..:: .:::::::. . :: .:.:: . .: : ::::::.:::.:. ::::
XP_005 LPPDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVKQIDTVAAEWPAQTNYL
860 870 880 890 900 910
970 980 990 1000 1010 1020
pF1KB3 YVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPE
:.:: : ::..: ..::: : :.::::::::::::. :. ::..: ::..:: :::
XP_005 YLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPE
920 930 940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KB3 TVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGT
:::::.: ::.:::.:.:.: ..:::. : : :.:.:::.:::.:. :... ...::
XP_005 TVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLGT
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KB3 SPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSA
:: :: ::.: :: .:: . ..: :. .. :. : .: ..: :::..::::::::.:
XP_005 SPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTVGYPCVVRPSYVLSGAA
1040 1050 1060 1070 1080 1090
1150 1160 1170 1180 1190 1200
pF1KB3 MNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVED
:::.... ....:: :. ::.:::::..::.. :.:...:::..:: : . :::::::.
XP_005 MNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVASDGVVAAIAISEHVEN
1100 1110 1120 1130 1140 1150
1210 1220 1230 1240 1250 1260
pF1KB3 AGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNL
::::::::::. : : :. ..:..: .. ... . ..::::.:...: ... :::::.
XP_005 AGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNV
1160 1170 1180 1190 1200 1210
1270 1280 1290 1300 1310 1320
pF1KB3 RASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRL
:.::::::::::::::.. .::.:..::.:. : : . :..:.:.::. ::
XP_005 RVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMT------GSGVVGVKVPQFSFSRL
1220 1230 1240 1250 1260 1270
1330 1340 1350 1360 1370 1380
pF1KB3 RDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPR--FLG
:: .: ::.:::::: :::. :.::::::::::::.:.::. : :.. . .:
XP_005 AGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIG-SYKNKSELLP
1280 1290 1300 1310 1320 1330
1390 1400 1410 1420 1430 1440
pF1KB3 VAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQE---GQNPSLSSIRKLIRDGSID
... :.. :..:.:. .:.:. . ..: .: : : .: :. : :: . . . ...
XP_005 TVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSILEQLAEKNFE
1340 1350 1360 1370 1380 1390
1450 1460 1470 1480 1490
pF1KB3 LVINLPNNN------TKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKS
::::: . ..:: .: :: :.: ..::. ... ::::.::.
XP_005 LVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQIGPAPPLK
1400 1410 1420 1430 1440 1450
1500
pF1KB3 LFHYRQYSAGKAA
XP_005 VHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMVCAMPNTRPPI
1460 1470 1480 1490 1500 1510
1507 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 20:35:12 2016 done: Thu Nov 3 20:35:15 2016
Total Scan time: 17.000 Total Display time: 0.820
Function used was FASTA [36.3.4 Apr, 2011]