FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3047, 1147 aa 1>>>pF1KB3047 1147 - 1147 aa - 1147 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6472+/-0.00131; mu= 7.1382+/- 0.079 mean_var=182.0143+/-36.115, 0's: 0 Z-trim(106.3): 40 B-trim: 6 in 1/49 Lambda= 0.095065 statistics sampled from 8913 (8932) to 8913 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.611), E-opt: 0.2 (0.274), width: 16 Scan time: 5.080 The best scores are: opt bits E(32554) CCDS3450.1 RFC1 gene_id:5981|Hs108|chr4 (1147) 7384 1026.4 0 CCDS56329.1 RFC1 gene_id:5981|Hs108|chr4 (1148) 7372 1024.8 0 >>CCDS3450.1 RFC1 gene_id:5981|Hs108|chr4 (1147 aa) initn: 7384 init1: 7384 opt: 7384 Z-score: 5482.8 bits: 1026.4 E(32554): 0 Smith-Waterman score: 7384; 100.0% identity (100.0% similar) in 1147 aa overlap (1-1147:1-1147) 10 20 30 40 50 60 pF1KB3 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 QQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 SLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 VDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 VDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 GAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 KDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 KDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDM 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 KKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 KKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 WLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 WLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB3 VALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 VALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB3 ASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKG 1090 1100 1110 1120 1130 1140 pF1KB3 KGKSSKK ::::::: CCDS34 KGKSSKK >>CCDS56329.1 RFC1 gene_id:5981|Hs108|chr4 (1148 aa) initn: 3975 init1: 3975 opt: 7372 Z-score: 5473.9 bits: 1024.8 E(32554): 0 Smith-Waterman score: 7372; 99.9% identity (99.9% similar) in 1148 aa overlap (1-1147:1-1148) 10 20 30 40 50 60 pF1KB3 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG 550 560 570 580 590 600 610 620 630 640 650 pF1KB3 QQGDQSCANKLLRWLRNWQKSSSEDKKHA-KFGKFSGKDDGSSFKAALLSGPPGVGKTTT ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: CCDS56 QQGDQSCANKLLRWLRNWQKSSSEDKKHAAKFGKFSGKDDGSSFKAALLSGPPGVGKTTT 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB3 ASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 ASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMD 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB3 EVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 EVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQI 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB3 KGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 KGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRA 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB3 KKDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 KKDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGD 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB3 MKKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MKKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFP 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB3 SWLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 SWLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQD 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB3 VVALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 VVALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAI 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB3 KASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 KASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRK 1090 1100 1110 1120 1130 1140 1140 pF1KB3 GKGKSSKK :::::::: CCDS56 GKGKSSKK 1147 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:14:06 2016 done: Thu Nov 3 12:14:06 2016 Total Scan time: 5.080 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]