FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3047, 1147 aa 1>>>pF1KB3047 1147 - 1147 aa - 1147 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.4224+/-0.000557; mu= 2.6746+/- 0.035 mean_var=214.2378+/-42.439, 0's: 0 Z-trim(114.1): 72 B-trim: 539 in 1/53 Lambda= 0.087625 statistics sampled from 23676 (23744) to 23676 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.278), width: 16 Scan time: 14.870 The best scores are: opt bits E(85289) NP_002904 (OMIM: 102579) replication factor C subu (1147) 7384 947.7 0 NP_001191676 (OMIM: 102579) replication factor C s (1148) 7372 946.2 0 XP_016864017 (OMIM: 102579) PREDICTED: replication (1121) 5919 762.5 0 XP_011512032 (OMIM: 102579) PREDICTED: replication (1122) 5896 759.6 2.4e-218 XP_011512033 (OMIM: 102579) PREDICTED: replication ( 978) 3274 428.1 1.3e-118 XP_011528502 (OMIM: 105400,162230,616924) PREDICTE ( 924) 266 47.8 0.00036 NP_066554 (OMIM: 105400,162230,616924) neurofilame (1020) 240 44.6 0.0038 >>NP_002904 (OMIM: 102579) replication factor C subunit (1147 aa) initn: 7384 init1: 7384 opt: 7384 Z-score: 5057.6 bits: 947.7 E(85289): 0 Smith-Waterman score: 7384; 100.0% identity (100.0% similar) in 1147 aa overlap (1-1147:1-1147) 10 20 30 40 50 60 pF1KB3 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 QQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 SLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 VDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 GAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 KDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDM 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 KKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 WLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 WLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB3 VALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB3 ASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKG 1090 1100 1110 1120 1130 1140 pF1KB3 KGKSSKK ::::::: NP_002 KGKSSKK >>NP_001191676 (OMIM: 102579) replication factor C subun (1148 aa) initn: 3975 init1: 3975 opt: 7372 Z-score: 5049.4 bits: 946.2 E(85289): 0 Smith-Waterman score: 7372; 99.9% identity (99.9% similar) in 1148 aa overlap (1-1147:1-1148) 10 20 30 40 50 60 pF1KB3 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG 550 560 570 580 590 600 610 620 630 640 650 pF1KB3 QQGDQSCANKLLRWLRNWQKSSSEDKKHA-KFGKFSGKDDGSSFKAALLSGPPGVGKTTT ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: NP_001 QQGDQSCANKLLRWLRNWQKSSSEDKKHAAKFGKFSGKDDGSSFKAALLSGPPGVGKTTT 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB3 ASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMD 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB3 EVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQI 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB3 KGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRA 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB3 KKDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGD 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB3 MKKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFP 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB3 SWLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SWLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQD 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB3 VVALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAI 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB3 KASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRK 1090 1100 1110 1120 1130 1140 1140 pF1KB3 GKGKSSKK :::::::: NP_001 GKGKSSKK >>XP_016864017 (OMIM: 102579) PREDICTED: replication fac (1121 aa) initn: 5868 init1: 5868 opt: 5919 Z-score: 4056.8 bits: 762.5 E(85289): 0 Smith-Waterman score: 7156; 97.7% identity (97.7% similar) in 1147 aa overlap (1-1147:1-1121) 10 20 30 40 50 60 pF1KB3 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK :::::::::::::::::::::::::::::::::: XP_016 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAE-------------------------- 190 200 210 250 260 270 280 290 300 pF1KB3 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB3 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB3 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB3 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB3 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB3 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB3 QQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTA 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB3 SLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDE 640 650 660 670 680 690 730 740 750 760 770 780 pF1KB3 VDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIK 700 710 720 730 740 750 790 800 810 820 830 840 pF1KB3 GAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAK 760 770 780 790 800 810 850 860 870 880 890 900 pF1KB3 KDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDM 820 830 840 850 860 870 910 920 930 940 950 960 pF1KB3 KKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPS 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KB3 WLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDV 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KB3 VALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIK 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KB3 ASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKG 1060 1070 1080 1090 1100 1110 pF1KB3 KGKSSKK ::::::: XP_016 KGKSSKK 1120 >>XP_011512032 (OMIM: 102579) PREDICTED: replication fac (1122 aa) initn: 4844 init1: 3430 opt: 5896 Z-score: 4041.1 bits: 759.6 E(85289): 2.4e-218 Smith-Waterman score: 7144; 97.6% identity (97.6% similar) in 1148 aa overlap (1-1147:1-1122) 10 20 30 40 50 60 pF1KB3 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK :::::::::::::::::::::::::::::::::: XP_011 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAE-------------------------- 190 200 210 250 260 270 280 290 300 pF1KB3 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB3 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB3 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB3 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB3 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB3 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG 520 530 540 550 560 570 610 620 630 640 650 pF1KB3 QQGDQSCANKLLRWLRNWQKSSSEDKKHA-KFGKFSGKDDGSSFKAALLSGPPGVGKTTT ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: XP_011 QQGDQSCANKLLRWLRNWQKSSSEDKKHAAKFGKFSGKDDGSSFKAALLSGPPGVGKTTT 580 590 600 610 620 630 660 670 680 690 700 710 pF1KB3 ASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMD 640 650 660 670 680 690 720 730 740 750 760 770 pF1KB3 EVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQI 700 710 720 730 740 750 780 790 800 810 820 830 pF1KB3 KGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRA 760 770 780 790 800 810 840 850 860 870 880 890 pF1KB3 KKDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGD 820 830 840 850 860 870 900 910 920 930 940 950 pF1KB3 MKKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFP 880 890 900 910 920 930 960 970 980 990 1000 1010 pF1KB3 SWLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQD 940 950 960 970 980 990 1020 1030 1040 1050 1060 1070 pF1KB3 VVALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAI 1000 1010 1020 1030 1040 1050 1080 1090 1100 1110 1120 1130 pF1KB3 KASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRK 1060 1070 1080 1090 1100 1110 1140 pF1KB3 GKGKSSKK :::::::: XP_011 GKGKSSKK 1120 >>XP_011512033 (OMIM: 102579) PREDICTED: replication fac (978 aa) initn: 3179 init1: 3179 opt: 3274 Z-score: 2250.6 bits: 428.1 E(85289): 1.3e-118 Smith-Waterman score: 5934; 85.3% identity (85.3% similar) in 1147 aa overlap (1-1147:1-978) 10 20 30 40 50 60 pF1KB3 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK :::::::::::::::: XP_011 TMPGKKSKYEIAVETE-------------------------------------------- 490 550 560 570 580 590 600 pF1KB3 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG XP_011 ------------------------------------------------------------ 610 620 630 640 650 660 pF1KB3 QQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTA XP_011 ------------------------------------------------------------ 670 680 690 700 710 720 pF1KB3 SLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDE ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 -----ELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDE 500 510 520 530 540 550 730 740 750 760 770 780 pF1KB3 VDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIK 560 570 580 590 600 610 790 800 810 820 830 840 pF1KB3 GAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAK 620 630 640 650 660 670 850 860 870 880 890 900 pF1KB3 KDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDM 680 690 700 710 720 730 910 920 930 940 950 960 pF1KB3 KKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPS 740 750 760 770 780 790 970 980 990 1000 1010 1020 pF1KB3 WLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDV 800 810 820 830 840 850 1030 1040 1050 1060 1070 1080 pF1KB3 VALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIK 860 870 880 890 900 910 1090 1100 1110 1120 1130 1140 pF1KB3 ASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKG 920 930 940 950 960 970 pF1KB3 KGKSSKK ::::::: XP_011 KGKSSKK >>XP_011528502 (OMIM: 105400,162230,616924) PREDICTED: n (924 aa) initn: 185 init1: 70 opt: 266 Z-score: 195.9 bits: 47.8 E(85289): 0.00036 Smith-Waterman score: 268; 23.3% identity (54.2% similar) in 506 aa overlap (174-644:447-924) 150 160 170 180 190 200 pF1KB3 NEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK-MVASKRKELSQNTDESGLNDEA :..:.:. ... .. : .: :.: ..: XP_011 PIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEK 420 430 440 450 460 470 210 220 230 240 250 260 pF1KB3 IAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKKARKDTEAGETFSSVQANLSKAE ::. . :. :.. : : .: . .: :. :. : ..:. . : XP_011 EAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKE 480 490 500 510 520 530 270 280 290 300 310 320 pF1KB3 KHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHSKSSADKIGEVSSP-KASSKLAI . : : .::. . :. ::.: .: ..:... :... .:..:: ::.: . XP_011 EAKSPAEVKSPE-----KAKSPEK-AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA 540 550 560 570 580 590 330 340 350 360 370 380 pF1KB3 MKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSSPAKKESVSPEDSEKKRTNYQA .. :.. . .. :.. .. .: :.:.:.:.:: :.:.:. .:: . :. .. .: XP_011 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKS-PVKEEAKTPEKA-KSPVKEEA 600 610 620 630 640 390 400 410 420 430 440 pF1KB3 YRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLESIERDEAKSLIERYGGKVTGNV ..:. : : : . : . .. ..::.: ... :. . : XP_011 -------KSPEKAKSPEKAKTLD--------VKSPEAKTPAKEEARSPADKFPEKAKSPV 650 660 670 680 690 450 460 470 480 490 pF1KB3 S-------KKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIRTMPGKKSKYEIAV- . : . : . ... : . . . .:. .. : ::.. : : XP_011 KEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPA 700 710 720 730 740 750 500 510 520 530 pF1KB3 --ETEMKKESKLERTPQKN-----VQGKR----------KISPSKKESESKKSRPTSKRD .:: ::.:: :..:.:. :. :. :. .:.:.:.::. :: ... XP_011 TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKE 760 770 780 790 800 810 540 550 560 570 580 pF1KB3 SLAKTIKKE-------TDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDK . ::. :: :.: : : . :.: : .. .. : .....: :. .. XP_011 APAKVEVKEDAKPKEKTEVAKKEPD--DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEE 820 830 840 850 860 870 590 600 610 620 630 640 pF1KB3 YKPTSLKTIIGQQGDQSCANKLLR-WLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALL : : ... :.. ... . .. .:::: :.: .: . . .: ... : XP_011 KPKTEAK---AKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 880 890 900 910 920 650 660 670 680 690 700 pF1KB3 SGPPGVGKTTTASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAAS >>NP_066554 (OMIM: 105400,162230,616924) neurofilament h (1020 aa) initn: 181 init1: 70 opt: 240 Z-score: 177.5 bits: 44.6 E(85289): 0.0038 Smith-Waterman score: 297; 23.7% identity (54.0% similar) in 607 aa overlap (84-644:439-1020) 60 70 80 90 100 pF1KB3 FKQKQPSKKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGK----ISRQDPVTYISE : ::. : : : . .: : ..: NP_066 EECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTE 410 420 430 440 450 460 110 120 130 140 150 160 pF1KB3 -TDEEDDFMCKKAASKSKENGRSTNSHLGTSNMKK--NEENTKTKNKPLSPIKLTPTSVL . ::.. :. .: .:.:. ... : . :. :: .. ... ::.: : NP_066 EVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPA 470 480 490 500 510 520 170 180 190 200 210 220 pF1KB3 DYFGTGSVQRSNKKMVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFA . . . . .. : : .: : .:. :: . . :.:. ... :. : NP_066 EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPE---KEEAKSPAEVKSPEK-A 530 540 550 560 570 580 230 240 250 260 270 280 pF1KB3 RTLAMLDEEPKTKKARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRK .. : :: :. :. : .. : :. . .. . : : : . :. : :: :.: NP_066 KSPA--KEEAKSPAEAKSPEKAK--SPVKEEAKSPAEAKSPVK-EEAKSPAEVKS--PEK 590 600 610 620 630 290 300 310 320 330 340 pF1KB3 QSKYESSKESQQHSKSSADKIGEVSSP-KASSKLAIMKRKEESSYKEIEPVASKRKENAI .: ...:... :... . :..:: ::.: . .. :.. . .. :.. .. NP_066 -AKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKS 640 650 660 670 680 690 350 360 370 380 390 400 pF1KB3 KLKGETKTPKKTKSSPAKKESVSPEDS-----EKKRTNYQAYRSYLNREGPKALGSKEIP .: :.:.:.:.:: :.:.:. ::: . :. .: .: .: ...:. . .: : NP_066 PVKEEAKSPEKAKS-PVKEEAKSPEKAKSPVKEEAKTPEKA-KSPVKEEAKSPEKAKS-P 700 710 720 730 740 750 410 420 430 440 450 pF1KB3 KGAENCLEGLIFVITGVLESIERDEAKSLIERYGGKVTGNVS-------KKTNYLVMGRD . :.. :. : . .. ..::.: ... :. . :. : . : NP_066 EKAKT-LD----VKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK 760 770 780 790 800 460 470 480 490 500 510 pF1KB3 SGQSKSDKAAALGTKIIDEDGLLNLIRTMPGKKSKYEIAV---ETEMKKESKLERTPQKN . ... : . . . .:. .. : ::.. : : .:: ::.:: :..:.:. NP_066 APEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE 810 820 830 840 850 860 520 530 540 pF1KB3 -----VQGKR----------KISPSKKESESKKSRPTSKRDSLAKTIKKE-------TDV :. :. :. .:.:.:.::. :: .... ::. :: :.: NP_066 APKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEV 870 880 890 900 910 920 550 560 570 580 590 600 pF1KB3 FWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIGQQGDQSCA : : . :.: : .. .. : .....: :. .. : : ... :.. . NP_066 AKKEPD--DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAK---AKEDDKTLS 930 940 950 960 970 980 610 620 630 640 650 660 pF1KB3 NKLLR-WLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTASLVCQEL .. . .. .:::: :.: .: . . .: ... : NP_066 KEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 990 1000 1010 1020 670 680 690 700 710 720 pF1KB3 GYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDEVDGMAGN 1147 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:14:07 2016 done: Thu Nov 3 12:14:09 2016 Total Scan time: 14.870 Total Display time: 0.260 Function used was FASTA [36.3.4 Apr, 2011]