FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3063, 715 aa 1>>>pF1KB3063 715 - 715 aa - 715 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2830+/-0.000907; mu= 14.9944+/- 0.055 mean_var=82.3426+/-16.496, 0's: 0 Z-trim(107.2): 30 B-trim: 5 in 1/49 Lambda= 0.141339 statistics sampled from 9431 (9457) to 9431 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.291), width: 16 Scan time: 4.030 The best scores are: opt bits E(32554) CCDS11752.1 SEC14L1 gene_id:6397|Hs108|chr17 ( 715) 4818 992.5 0 CCDS42385.1 SEC14L1 gene_id:6397|Hs108|chr17 ( 719) 4818 992.5 0 CCDS45789.1 SEC14L1 gene_id:6397|Hs108|chr17 ( 681) 4579 943.8 0 CCDS45403.1 SEC14L5 gene_id:9717|Hs108|chr16 ( 696) 2392 497.8 2.2e-140 CCDS54517.1 SEC14L4 gene_id:284904|Hs108|chr22 ( 360) 655 143.6 5.1e-34 CCDS13878.1 SEC14L4 gene_id:284904|Hs108|chr22 ( 406) 655 143.6 5.7e-34 CCDS13877.1 SEC14L3 gene_id:266629|Hs108|chr22 ( 400) 637 139.9 7.2e-33 CCDS46685.1 SEC14L2 gene_id:23541|Hs108|chr22 ( 392) 633 139.1 1.2e-32 CCDS13876.1 SEC14L2 gene_id:23541|Hs108|chr22 ( 403) 633 139.1 1.3e-32 CCDS54518.1 SEC14L6 gene_id:730005|Hs108|chr22 ( 397) 597 131.7 2e-30 CCDS58801.1 SEC14L3 gene_id:266629|Hs108|chr22 ( 341) 525 117.0 4.7e-26 CCDS58800.1 SEC14L3 gene_id:266629|Hs108|chr22 ( 323) 461 104.0 3.8e-22 CCDS56228.1 SEC14L2 gene_id:23541|Hs108|chr22 ( 320) 352 81.7 1.8e-15 >>CCDS11752.1 SEC14L1 gene_id:6397|Hs108|chr17 (715 aa) initn: 4818 init1: 4818 opt: 4818 Z-score: 5307.1 bits: 992.5 E(32554): 0 Smith-Waterman score: 4818; 99.9% identity (99.9% similar) in 715 aa overlap (1-715:1-715) 10 20 30 40 50 60 pF1KB3 MVQKYQSPVRVYKYPFELIMAAYERRFPTCPLIPMFVGSDTVNEFKSEDGAIHVIERRCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MVQKYQSPVRVYKYPFELIMAAYERRFPTCPLIPMFVGSDTVNEFKSEDGAIHVIERRCK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LDVDAPRLLKKIAGVDYVYFVQKNSLNSRERTLHIEAYNETFSNRVIINEHCCYTVHPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LDVDAPRLLKKIAGVDYVYFVQKNSLNSRERTLHIEAYNETFSNRVIINEHCCYTVHPEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EDWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLRQLEEEGITFVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EDWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLRQLEEEGITFVPR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 WSPPSITPSSETSSSSSKKQAASMAVVIPEAALKEGLSGDALSSPSAPEPVVGTPDDKLD ::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 WSPPSITTSSETSSSSSKKQAASMAVVIPEAALKEGLSGDALSSPSAPEPVVGTPDDKLD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 ADYIKRYLGDLTPLQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREIMCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ADYIKRYLGDLTPLQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREIMCQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SLTWRKQHQVDYILETWTPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SLTWRKQHQVDYILETWTPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 VEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 EIIPDFLSGECMCEVPEGGLVPKSLYRTAEELENEDLKLWTETIYQSASVFKGAPHEILI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EIIPDFLSGECMCEVPEGGLVPKSLYRTAEELENEDLKLWTETIYQSASVFKGAPHEILI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 QIVDASSVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 QIVDASSVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 LGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAASSLPRVDDVLASLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAASSLPRVDDVLASLQ 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 VSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSHSSSMISR ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSHSSSMISR 670 680 690 700 710 >>CCDS42385.1 SEC14L1 gene_id:6397|Hs108|chr17 (719 aa) initn: 4818 init1: 4818 opt: 4818 Z-score: 5307.1 bits: 992.5 E(32554): 0 Smith-Waterman score: 4818; 99.9% identity (99.9% similar) in 715 aa overlap (1-715:1-715) 10 20 30 40 50 60 pF1KB3 MVQKYQSPVRVYKYPFELIMAAYERRFPTCPLIPMFVGSDTVNEFKSEDGAIHVIERRCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MVQKYQSPVRVYKYPFELIMAAYERRFPTCPLIPMFVGSDTVNEFKSEDGAIHVIERRCK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LDVDAPRLLKKIAGVDYVYFVQKNSLNSRERTLHIEAYNETFSNRVIINEHCCYTVHPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LDVDAPRLLKKIAGVDYVYFVQKNSLNSRERTLHIEAYNETFSNRVIINEHCCYTVHPEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EDWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLRQLEEEGITFVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 EDWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLRQLEEEGITFVPR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 WSPPSITPSSETSSSSSKKQAASMAVVIPEAALKEGLSGDALSSPSAPEPVVGTPDDKLD ::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 WSPPSITTSSETSSSSSKKQAASMAVVIPEAALKEGLSGDALSSPSAPEPVVGTPDDKLD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 ADYIKRYLGDLTPLQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREIMCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ADYIKRYLGDLTPLQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREIMCQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SLTWRKQHQVDYILETWTPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SLTWRKQHQVDYILETWTPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 EALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 VEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 EIIPDFLSGECMCEVPEGGLVPKSLYRTAEELENEDLKLWTETIYQSASVFKGAPHEILI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 EIIPDFLSGECMCEVPEGGLVPKSLYRTAEELENEDLKLWTETIYQSASVFKGAPHEILI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 QIVDASSVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 QIVDASSVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 LGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAASSLPRVDDVLASLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAASSLPRVDDVLASLQ 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 VSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSHSSSMISR ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSHSSSMISRWRFC 670 680 690 700 710 >>CCDS45789.1 SEC14L1 gene_id:6397|Hs108|chr17 (681 aa) initn: 4579 init1: 4579 opt: 4579 Z-score: 5044.1 bits: 943.8 E(32554): 0 Smith-Waterman score: 4579; 99.9% identity (99.9% similar) in 681 aa overlap (35-715:1-681) 10 20 30 40 50 60 pF1KB3 YQSPVRVYKYPFELIMAAYERRFPTCPLIPMFVGSDTVNEFKSEDGAIHVIERRCKLDVD :::::::::::::::::::::::::::::: CCDS45 MFVGSDTVNEFKSEDGAIHVIERRCKLDVD 10 20 30 70 80 90 100 110 120 pF1KB3 APRLLKKIAGVDYVYFVQKNSLNSRERTLHIEAYNETFSNRVIINEHCCYTVHPENEDWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 APRLLKKIAGVDYVYFVQKNSLNSRERTLHIEAYNETFSNRVIINEHCCYTVHPENEDWT 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB3 CFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLRQLEEEGITFVPRWSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 CFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLRQLEEEGITFVPRWSPP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB3 SITPSSETSSSSSKKQAASMAVVIPEAALKEGLSGDALSSPSAPEPVVGTPDDKLDADYI ::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 SITTSSETSSSSSKKQAASMAVVIPEAALKEGLSGDALSSPSAPEPVVGTPDDKLDADYI 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB3 KRYLGDLTPLQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREIMCQSLTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 KRYLGDLTPLQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREIMCQSLTW 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB3 RKQHQVDYILETWTPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 RKQHQVDYILETWTPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALL 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB3 RYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 RYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEAN 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB3 YPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 YPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIP 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB3 DFLSGECMCEVPEGGLVPKSLYRTAEELENEDLKLWTETIYQSASVFKGAPHEILIQIVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DFLSGECMCEVPEGGLVPKSLYRTAEELENEDLKLWTETIYQSASVFKGAPHEILIQIVD 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB3 ASSVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ASSVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRD 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB3 YSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAASSLPRVDDVLASLQVSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 YSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAASSLPRVDDVLASLQVSSH 580 590 600 610 620 630 670 680 690 700 710 pF1KB3 KCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSHSSSMISR ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 KCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSHSSSMISR 640 650 660 670 680 >>CCDS45403.1 SEC14L5 gene_id:9717|Hs108|chr16 (696 aa) initn: 3306 init1: 1803 opt: 2392 Z-score: 2633.8 bits: 497.8 E(32554): 2.2e-140 Smith-Waterman score: 3341; 67.0% identity (86.1% similar) in 719 aa overlap (1-715:1-696) 10 20 30 40 50 60 pF1KB3 MVQKYQSPVRVYKYPFELIMAAYERRFPTCPLIPMFVGSDTVNEFKSEDGAIHVIERRCK :::.::::::::::::::.:::::.:::::: ::.:.::... : .: :::.::.:: :. CCDS45 MVQRYQSPVRVYKYPFELVMAAYEKRFPTCPQIPVFLGSEVLRESRSPDGAVHVVERSCR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LDVDAPRLLKKIAGVDYVYFVQKNSLNSRERTLHIEAYNETFSNRVIINEHCCYTVHPEN : :::::::.:::::..: ::: : :: .:::: :::.::::.:::..:::: ::::::: CCDS45 LRVDAPRLLRKIAGVEHVVFVQTNILNWKERTLLIEAHNETFANRVVVNEHCSYTVHPEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EDWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLRQLEEEGITFVPR ::::::::::::::.::::::...:::::::::.:.:.:::.::.:: .: .: . .:: CCDS45 EDWTCFEQSASLDIRSFFGFENALEKIAMKQYTANVKRGKEVIEHYLNELISQGTSHIPR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 WSPPSITPSSETSSSSSKKQAASMAVVIPEAALKEGLSGDALSSPSAPEPVVGTPDDKLD :.: . .. .... .. .:. . :...: : :: . :. :::: CCDS45 WTPAPVREE-DARNQAGPRDPSSLEAHGPRSTL-----GPALEA-------VSMDGDKLD 190 200 210 220 250 260 270 280 290 300 pF1KB3 ADYIKRYLGDLTPLQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREIMCQ ::::.: :: :::.::::::.::.::::::::::::::::::::::.::..:::::.. : CCDS45 ADYIERCLGHLTPMQESCLIQLRHWLQETHKGKIPKDEHILRFLRAHDFHLDKAREMLRQ 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 SLTWRKQHQVDYILETWTPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGE ::.:::::::: .:.:: :: .:...::::::..: ::::::.:::::::::::..:.:: CCDS45 SLSWRKQHQVDLLLQTWQPPALLEEFYAGGWHYQDIDGRPLYILRLGQMDTKGLMKAVGE 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 EALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEV :::::.:::.:::: .::: .:. .::::::::::.::::::::::::::::::::.::: CCDS45 EALLRHVLSVNEEGQKRCEGSTRQLGRPISSWTCLLDLEGLNMRHLWRPGVKALLRMIEV 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB3 VEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDK :: :::::::::::.::::::::::::.::::..:::::::::.:..:::::::.::.:. CCDS45 VEDNYPETLGRLLIVRAPRVFPVLWTLISPFINENTRRKFLIYSGSNYQGPGGLVDYLDR 410 420 430 440 450 460 490 500 510 520 530 pF1KB3 EIIPDFLSGECMCEVPEGGLVPKSLYRTAEELENED-LKLWTETIYQSASVFKGAPHEIL :.:::::.:: .:.:::::::::::: : :: :. : : :.:: :.::::..:::::. CCDS45 EVIPDFLGGESVCNVPEGGLVPKSLYMTEEEQEHTDQLWQWSET-YHSASVLRGAPHEVA 470 480 490 500 510 520 540 550 560 570 580 590 pF1KB3 IQIVDASSVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNV-QLIDKV ..:... ::::::::. .::.::..::.:..:. :::. :: ::::: CCDS45 VEILEGESVITWDFDILRGDVVFSLYHTKQAPR------LGAR---EPGTRASGQLIDKG 530 540 550 560 570 600 610 620 630 640 650 pF1KB3 WQLGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAASSLPRVDDVLAS : :::::: ::.::.:.::::.:::::::::: :.:::..:: :. .: ::: :::::.. CCDS45 WVLGRDYSRVEAPLVCREGESIQGSHVTRWPGVYLLQWQMHSPPSSVACSLPGVDDVLTA 580 590 600 610 620 630 660 670 680 690 700 710 pF1KB3 LQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSS--QSHSSSMISR :. . :::..:: ::..::::::::.:::: ::::::::::.::: ::::::..:: CCDS45 LHSPGPKCKLLYYCEVLASEDFRGSMSSLESCTSGFSQLSAATSSSSSGQSHSSSLVSR 640 650 660 670 680 690 >>CCDS54517.1 SEC14L4 gene_id:284904|Hs108|chr22 (360 aa) initn: 508 init1: 459 opt: 655 Z-score: 724.2 bits: 143.6 E(32554): 5.1e-34 Smith-Waterman score: 655; 33.0% identity (66.4% similar) in 342 aa overlap (248-577:5-332) 220 230 240 250 260 270 pF1KB3 SGDALSSPSAPEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGKIPK- .:::.: :. : :.:. ::. .:. CCDS54 MSSRVGDLSPQQQEALARFRENLQDLLP-ILPNA 10 20 30 280 290 300 310 320 330 pF1KB3 -DEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILETWTPPQVLQDYYAGGWHHHD : .::.::::.:...:..... . . .:::...: :. :: ::.:.: : .:: .: CCDS54 DDYFLLRWLRARNFDLQKSEDMLRRHMEFRKQQDLDNIV-TWQPPEVIQLYDSGGLCGYD 40 50 60 70 80 90 340 350 360 370 380 390 pF1KB3 KDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCL .: :.: .:..: :::. . ... ..: ... : :..:: .:. .:: : . CCDS54 YEGCPVYFNIIGSLDPKGLLLSASKQDMIRKRIKVCELLLHECELQTQKLGRKIEMALMV 100 110 120 130 140 150 400 410 420 430 440 450 pF1KB3 VDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDN :.:::...:::.:.:.. ... ..:::::::: :...:::..::: ..::. :.... CCDS54 FDMEGLSLKHLWKPAVEVYQQFFSILEANYPETLKNLIVIRAPKLFPVAFNLVKSFMSEE 160 170 180 190 200 210 460 470 480 490 500 pF1KB3 TRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSG---------ECMCEVPEGGLVPKSLY ::::..: :.... : .:. . .: ..: .:. .. :: :::: : CCDS54 TRRKIVIL-GDNWKQE--LTKFISPDQLPVEFGGTMTDPDGNPKCLTKINYGGEVPKSYY 220 230 240 250 260 510 520 530 540 550 560 pF1KB3 RTAEELENEDLKLWTETIYQSASVFKGAPHEILIQIVDASSVITWDFDVCKGDIVFNIY- :...: : .. :: .:. .. .:. . :. :.: ::: :... CCDS54 LC------EQVRLQYE---HTRSVGRGSSLQVENEILFPGCVLRWQFASDGGDIGFGVFL 270 280 290 300 310 320 570 580 590 600 610 620 pF1KB3 HSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHV ..: . : .. CCDS54 KTKMGEQQSAREMTEVLPSQRYNAHMVPEDGSLTCLQAGV 330 340 350 360 >>CCDS13878.1 SEC14L4 gene_id:284904|Hs108|chr22 (406 aa) initn: 508 init1: 459 opt: 655 Z-score: 723.3 bits: 143.6 E(32554): 5.7e-34 Smith-Waterman score: 655; 33.0% identity (66.4% similar) in 342 aa overlap (248-577:5-332) 220 230 240 250 260 270 pF1KB3 SGDALSSPSAPEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGKIPK- .:::.: :. : :.:. ::. .:. CCDS13 MSSRVGDLSPQQQEALARFRENLQDLLP-ILPNA 10 20 30 280 290 300 310 320 330 pF1KB3 -DEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILETWTPPQVLQDYYAGGWHHHD : .::.::::.:...:..... . . .:::...: :. :: ::.:.: : .:: .: CCDS13 DDYFLLRWLRARNFDLQKSEDMLRRHMEFRKQQDLDNIV-TWQPPEVIQLYDSGGLCGYD 40 50 60 70 80 90 340 350 360 370 380 390 pF1KB3 KDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCL .: :.: .:..: :::. . ... ..: ... : :..:: .:. .:: : . CCDS13 YEGCPVYFNIIGSLDPKGLLLSASKQDMIRKRIKVCELLLHECELQTQKLGRKIEMALMV 100 110 120 130 140 150 400 410 420 430 440 450 pF1KB3 VDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDN :.:::...:::.:.:.. ... ..:::::::: :...:::..::: ..::. :.... CCDS13 FDMEGLSLKHLWKPAVEVYQQFFSILEANYPETLKNLIVIRAPKLFPVAFNLVKSFMSEE 160 170 180 190 200 210 460 470 480 490 500 pF1KB3 TRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSG---------ECMCEVPEGGLVPKSLY ::::..: :.... : .:. . .: ..: .:. .. :: :::: : CCDS13 TRRKIVIL-GDNWKQE--LTKFISPDQLPVEFGGTMTDPDGNPKCLTKINYGGEVPKSYY 220 230 240 250 260 510 520 530 540 550 560 pF1KB3 RTAEELENEDLKLWTETIYQSASVFKGAPHEILIQIVDASSVITWDFDVCKGDIVFNIY- :...: : .. :: .:. .. .:. . :. :.: ::: :... CCDS13 LC------EQVRLQYE---HTRSVGRGSSLQVENEILFPGCVLRWQFASDGGDIGFGVFL 270 280 290 300 310 320 570 580 590 600 610 620 pF1KB3 HSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHV ..: . : .. CCDS13 KTKMGEQQSAREMTEVLPSQRYNAHMVPEDGSLTCLQAGVYVLRFDNTYSRMHAKKLSYT 330 340 350 360 370 380 >>CCDS13877.1 SEC14L3 gene_id:266629|Hs108|chr22 (400 aa) initn: 514 init1: 395 opt: 637 Z-score: 703.6 bits: 139.9 E(32554): 7.2e-33 Smith-Waterman score: 637; 31.6% identity (66.9% similar) in 329 aa overlap (248-565:5-319) 220 230 240 250 260 270 pF1KB3 SGDALSSPSAPEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKG-KIPK .:::.: : : ..:. .:.. . : CCDS13 MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPD 10 20 30 280 290 300 310 320 330 pF1KB3 DEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILETWTPPQVLQDYYAGGWHHHDK : .::.::::.:...:.. .. . . .:: ..:.::. : ::.:.: :. :: .:. CCDS13 DYFLLRWLRARNFDLQKSEALLRKYMEFRKTMDIDHILD-WQPPEVIQKYMPGGLCGYDR 40 50 60 70 80 90 340 350 360 370 380 390 pF1KB3 DGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLV :: :.. .: .: :::. .. .. ::. . :. :..:. .:. .:. : . . . CCDS13 DGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCERILHECDLQTERLGKKIETIVMIF 100 110 120 130 140 150 400 410 420 430 440 450 pF1KB3 DLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNT : :::...:.:.: :.. ... ..: :::::: .::..: ..::: ..:..::....: CCDS13 DCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDT 160 170 180 190 200 210 460 470 480 490 500 pF1KB3 RRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSG---------ECMCEVPEGGLVPKSLYR :::... ::... ::: :. : .: ..: .:. .. :: .:::.: CCDS13 RRKIIVL-GNNWKE--GLLKLISPEELPAQFGGTLTDPDGNPKCLTKINYGGEIPKSMY- 220 230 240 250 260 510 520 530 540 550 560 pF1KB3 TAEELENEDLKLWTETIYQ-SASVFKGAPHEILIQIVDASSVITWDFDVCKGDIVFNIYH .. ..: :. :... .:. :.. .:. . :. :.:. .:: :... CCDS13 ---------VRDQVKTQYEHSVQINRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFL 270 280 290 300 310 320 570 580 590 600 610 620 pF1KB3 SKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHVT CCDS13 KTKMGERQRAGEMTDVLPSQRYNAHMVPEDGNLTCSEAGVYVLRFDNTYSFVHAKKVSFT 330 340 350 360 370 380 >>CCDS46685.1 SEC14L2 gene_id:23541|Hs108|chr22 (392 aa) initn: 522 init1: 414 opt: 633 Z-score: 699.3 bits: 139.1 E(32554): 1.2e-32 Smith-Waterman score: 633; 31.4% identity (66.2% similar) in 328 aa overlap (248-565:5-319) 220 230 240 250 260 270 pF1KB3 SGDALSSPSAPEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKG-KIPK .:::.: :. : ..:. .:.. . : CCDS46 MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPD 10 20 30 280 290 300 310 320 330 pF1KB3 DEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILETWTPPQVLQDYYAGGWHHHDK : .::.::::.:...:.. .. . . .:::...: :. .: ::.:.:.: .:: .: CCDS46 DYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDNII-SWQPPEVIQQYLSGGMCGYDL 40 50 60 70 80 90 340 350 360 370 380 390 pF1KB3 DGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLV :: :.. .: .:.:::. . ... ::: . : :..: ..: .:: . . : . CCDS46 DGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRECELLLQECAHQTTKLGRKVETITIIY 100 110 120 130 140 150 400 410 420 430 440 450 pF1KB3 DLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNT : :::...:::.:.:.: ... . : :::::: ::....::..::: ..:..::....: CCDS46 DCEGLGLKHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDT 160 170 180 190 200 210 460 470 480 490 500 pF1KB3 RRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSG---------ECMCEVPEGGLVPKSLYR :.:... ..: . :: .:. . .: .: .: .. :: .:.. : CCDS46 RKKIMVLGANWKEV---LLKHISPDQVPVEYGGTMTDPDGNPKCKSKINYGGDIPRKYYV 220 230 240 250 260 270 510 520 530 540 550 560 pF1KB3 TAEELENEDLKLWTETIYQSASVFKGAPHEILIQIVDASSVITWDFDVCKGDIVFNIYHS ...: : .:... .:. :.. .:. . :. :.: .:. :.:. CCDS46 R------DQVKQQYE---HSVQISRGSSHQVEYEILFPGCVLRWQFMSDGADVGFGIFLK 280 290 300 310 320 570 580 590 600 610 620 pF1KB3 KRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHVTR CCDS46 TKMGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGICKYLCLGNALKPHVQLSACEV 330 340 350 360 370 380 >>CCDS13876.1 SEC14L2 gene_id:23541|Hs108|chr22 (403 aa) initn: 522 init1: 414 opt: 633 Z-score: 699.2 bits: 139.1 E(32554): 1.3e-32 Smith-Waterman score: 633; 31.4% identity (66.2% similar) in 328 aa overlap (248-565:5-319) 220 230 240 250 260 270 pF1KB3 SGDALSSPSAPEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKG-KIPK .:::.: :. : ..:. .:.. . : CCDS13 MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPD 10 20 30 280 290 300 310 320 330 pF1KB3 DEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILETWTPPQVLQDYYAGGWHHHDK : .::.::::.:...:.. .. . . .:::...: :. .: ::.:.:.: .:: .: CCDS13 DYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDNII-SWQPPEVIQQYLSGGMCGYDL 40 50 60 70 80 90 340 350 360 370 380 390 pF1KB3 DGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLV :: :.. .: .:.:::. . ... ::: . : :..: ..: .:: . . : . CCDS13 DGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRECELLLQECAHQTTKLGRKVETITIIY 100 110 120 130 140 150 400 410 420 430 440 450 pF1KB3 DLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNT : :::...:::.:.:.: ... . : :::::: ::....::..::: ..:..::....: CCDS13 DCEGLGLKHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDT 160 170 180 190 200 210 460 470 480 490 500 pF1KB3 RRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSG---------ECMCEVPEGGLVPKSLYR :.:... ..: . :: .:. . .: .: .: .. :: .:.. : CCDS13 RKKIMVLGANWKEV---LLKHISPDQVPVEYGGTMTDPDGNPKCKSKINYGGDIPRKYYV 220 230 240 250 260 270 510 520 530 540 550 560 pF1KB3 TAEELENEDLKLWTETIYQSASVFKGAPHEILIQIVDASSVITWDFDVCKGDIVFNIYHS ...: : .:... .:. :.. .:. . :. :.: .:. :.:. CCDS13 R------DQVKQQYE---HSVQISRGSSHQVEYEILFPGCVLRWQFMSDGADVGFGIFLK 280 290 300 310 320 570 580 590 600 610 620 pF1KB3 KRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHVTR CCDS13 TKMGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGIYVLRFDNTYSFIHAKKVNFTV 330 340 350 360 370 380 >>CCDS54518.1 SEC14L6 gene_id:730005|Hs108|chr22 (397 aa) initn: 468 init1: 419 opt: 597 Z-score: 659.6 bits: 131.7 E(32554): 2e-30 Smith-Waterman score: 597; 31.7% identity (65.5% similar) in 328 aa overlap (248-565:5-319) 220 230 240 250 260 270 pF1KB3 SGDALSSPSAPEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKG-KIPK .:::.: ::. : ..:. .:.. .. : CCDS54 MSGQVGDLSPSQEKSLAQFRENIQDVLSALPNPD 10 20 30 280 290 300 310 320 330 pF1KB3 DEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILETWTPPQVLQDYYAGGWHHHDK : .::.:.::.:...:..... . . .:::... :: .: ::.:.. : :.: :: CCDS54 DYFLLRWLQARSFDLQKSEDMLRKHMEFRKQQDLANIL-AWQPPEVVRLYNANGICGHDG 40 50 60 70 80 90 340 350 360 370 380 390 pF1KB3 DGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLV .: :.. .:..: :::. . ... ::: . : ::.:: ... .:. . . . CCDS54 EGSPVWYHIVGSLDPKGLLLSASKQELLRDSFRSCELLLRECELQSQKLGKRVEKIIAIF 100 110 120 130 140 150 400 410 420 430 440 450 pF1KB3 DLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNT ::::..: ::.::.. : ... ..:::::: : :...:::..: : ..::. .....: CCDS54 GLEGLGLRDLWKPGIELLQEFFSALEANYPEILKSLIVVRAPKLFAVAFNLVKSYMSEET 160 170 180 190 200 210 460 470 480 490 500 pF1KB3 RRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSG---------ECMCEVPEGGLVPKSLYR ::: .: :.... : .:. . .: ..: .:. .. :: :::: : CCDS54 RRKVVIL-GDNWKQE--LTKFISPDQLPVEFGGTMTDPDGNPKCLTKINYGGEVPKSYYL 220 230 240 250 260 270 510 520 530 540 550 560 pF1KB3 TAEELENEDLKLWTETIYQSASVFKGAPHEILIQIVDASSVITWDFDVCKGDIVFNIYHS ....: : .. :: .:. .. .:. . :. :.: ::: :... CCDS54 C------KQVRLQYE---HTRSVGRGSSLQVENEILFPGCVLRWQFASDGGDIGFGVFLK 280 290 300 310 320 570 580 590 600 610 620 pF1KB3 KRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHVTR CCDS54 TKMGERQRAREMTEVLPSQRYNAHMVPEDGILTCLQAGSYVLRFYNTYSLVHSKRISYTV 330 340 350 360 370 380 715 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:36:01 2016 done: Thu Nov 3 20:36:02 2016 Total Scan time: 4.030 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]