FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3064, 410 aa 1>>>pF1KB3064 410 - 410 aa - 410 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6826+/-0.00044; mu= 17.2538+/- 0.027 mean_var=181.9801+/-38.768, 0's: 0 Z-trim(114.2): 448 B-trim: 287 in 1/54 Lambda= 0.095074 statistics sampled from 23336 (23908) to 23336 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.28), width: 16 Scan time: 8.260 The best scores are: opt bits E(85289) NP_000421 (OMIM: 601545,607432) platelet-activatin ( 410) 2795 396.3 7e-110 XP_016880189 (OMIM: 601545,607432) PREDICTED: plat ( 410) 2795 396.3 7e-110 XP_016880188 (OMIM: 601545,607432) PREDICTED: plat ( 410) 2795 396.3 7e-110 XP_016880190 (OMIM: 601545,607432) PREDICTED: plat ( 410) 2795 396.3 7e-110 XP_011522205 (OMIM: 601545,607432) PREDICTED: plat ( 428) 2726 386.9 5.1e-107 XP_011522203 (OMIM: 601545,607432) PREDICTED: plat ( 428) 2726 386.9 5.1e-107 XP_011522204 (OMIM: 601545,607432) PREDICTED: plat ( 428) 2726 386.9 5.1e-107 XP_016880191 (OMIM: 601545,607432) PREDICTED: plat ( 345) 2387 340.3 4.5e-93 XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 475 78.0 3.9e-14 NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 475 78.0 3.9e-14 NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 475 78.0 3.9e-14 NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436) 416 70.1 1.2e-11 NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478) 416 70.1 1.3e-11 NP_001188493 (OMIM: 605961) pleiotropic regulator ( 505) 392 66.9 1.3e-10 NP_002660 (OMIM: 605961) pleiotropic regulator 1 i ( 514) 392 66.9 1.3e-10 NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 388 66.0 1.5e-10 XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 384 66.0 3.2e-10 XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 384 66.0 3.2e-10 NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 384 66.0 3.2e-10 XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 384 66.0 3.2e-10 XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 384 66.0 3.3e-10 XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672) 384 66.0 3.3e-10 XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 384 66.0 3.3e-10 XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675) 384 66.0 3.3e-10 XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675) 384 66.0 3.3e-10 XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675) 384 66.0 3.3e-10 XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675) 384 66.0 3.3e-10 XP_011531867 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 365 62.7 1.2e-09 XP_011531866 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 365 62.7 1.2e-09 XP_011531865 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 365 62.7 1.2e-09 XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300) 365 62.8 1.3e-09 XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326) 365 62.9 1.3e-09 NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 365 62.9 1.4e-09 XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374) 365 63.0 1.4e-09 NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 365 63.0 1.5e-09 XP_011510137 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 350 60.8 5.6e-09 XP_016860389 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 350 60.8 5.6e-09 XP_016860391 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 350 60.8 5.6e-09 XP_016860390 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 350 60.8 5.6e-09 XP_016860387 (OMIM: 612173) PREDICTED: sperm-assoc ( 390) 350 60.9 6.1e-09 NP_008882 (OMIM: 601787) transcription initiation ( 800) 354 62.0 6.2e-09 XP_016860386 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 350 61.1 7.1e-09 XP_016860385 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 350 61.1 7.1e-09 XP_011510124 (OMIM: 612173) PREDICTED: sperm-assoc ( 528) 350 61.1 7.2e-09 XP_011510125 (OMIM: 612173) PREDICTED: sperm-assoc ( 528) 350 61.1 7.2e-09 XP_011510123 (OMIM: 612173) PREDICTED: sperm-assoc ( 537) 350 61.2 7.3e-09 XP_011510120 (OMIM: 612173) PREDICTED: sperm-assoc ( 577) 350 61.2 7.6e-09 XP_011510121 (OMIM: 612173) PREDICTED: sperm-assoc ( 577) 350 61.2 7.6e-09 XP_011510119 (OMIM: 612173) PREDICTED: sperm-assoc ( 582) 350 61.2 7.6e-09 XP_011510117 (OMIM: 612173) PREDICTED: sperm-assoc ( 592) 350 61.2 7.7e-09 >>NP_000421 (OMIM: 601545,607432) platelet-activating fa (410 aa) initn: 2795 init1: 2795 opt: 2795 Z-score: 2093.7 bits: 396.3 E(85289): 7e-110 Smith-Waterman score: 2795; 100.0% identity (100.0% similar) in 410 aa overlap (1-410:1-410) 10 20 30 40 50 60 pF1KB3 MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 TLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR :::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 370 380 390 400 410 >>XP_016880189 (OMIM: 601545,607432) PREDICTED: platelet (410 aa) initn: 2795 init1: 2795 opt: 2795 Z-score: 2093.7 bits: 396.3 E(85289): 7e-110 Smith-Waterman score: 2795; 100.0% identity (100.0% similar) in 410 aa overlap (1-410:1-410) 10 20 30 40 50 60 pF1KB3 MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 TLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 370 380 390 400 410 >>XP_016880188 (OMIM: 601545,607432) PREDICTED: platelet (410 aa) initn: 2795 init1: 2795 opt: 2795 Z-score: 2093.7 bits: 396.3 E(85289): 7e-110 Smith-Waterman score: 2795; 100.0% identity (100.0% similar) in 410 aa overlap (1-410:1-410) 10 20 30 40 50 60 pF1KB3 MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 TLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 370 380 390 400 410 >>XP_016880190 (OMIM: 601545,607432) PREDICTED: platelet (410 aa) initn: 2795 init1: 2795 opt: 2795 Z-score: 2093.7 bits: 396.3 E(85289): 7e-110 Smith-Waterman score: 2795; 100.0% identity (100.0% similar) in 410 aa overlap (1-410:1-410) 10 20 30 40 50 60 pF1KB3 MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 TLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 370 380 390 400 410 >>XP_011522205 (OMIM: 601545,607432) PREDICTED: platelet (428 aa) initn: 2726 init1: 2726 opt: 2726 Z-score: 2042.4 bits: 386.9 E(85289): 5.1e-107 Smith-Waterman score: 2749; 95.8% identity (95.8% similar) in 428 aa overlap (1-410:1-428) 10 20 30 40 pF1KB3 MVLSQRQRDEL------------------NRAIADYLRSNGYEEAYSVFKKEAELDVNEE ::::::::::: ::::::::::::::::::::::::::::::: XP_011 MVLSQRQRDELDWFQRGEDSILNKADEARNRAIADYLRSNGYEEAYSVFKKEAELDVNEE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB3 LDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKY 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB3 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB3 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB3 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB3 SWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVR 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB3 GVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQ 370 380 390 400 410 420 410 pF1KB3 TVKVWECR :::::::: XP_011 TVKVWECR >>XP_011522203 (OMIM: 601545,607432) PREDICTED: platelet (428 aa) initn: 2726 init1: 2726 opt: 2726 Z-score: 2042.4 bits: 386.9 E(85289): 5.1e-107 Smith-Waterman score: 2749; 95.8% identity (95.8% similar) in 428 aa overlap (1-410:1-428) 10 20 30 40 pF1KB3 MVLSQRQRDEL------------------NRAIADYLRSNGYEEAYSVFKKEAELDVNEE ::::::::::: ::::::::::::::::::::::::::::::: XP_011 MVLSQRQRDELDWFQRGEDSILNKADEARNRAIADYLRSNGYEEAYSVFKKEAELDVNEE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB3 LDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKY 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB3 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB3 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB3 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB3 SWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVR 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB3 GVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQ 370 380 390 400 410 420 410 pF1KB3 TVKVWECR :::::::: XP_011 TVKVWECR >>XP_011522204 (OMIM: 601545,607432) PREDICTED: platelet (428 aa) initn: 2726 init1: 2726 opt: 2726 Z-score: 2042.4 bits: 386.9 E(85289): 5.1e-107 Smith-Waterman score: 2749; 95.8% identity (95.8% similar) in 428 aa overlap (1-410:1-428) 10 20 30 40 pF1KB3 MVLSQRQRDEL------------------NRAIADYLRSNGYEEAYSVFKKEAELDVNEE ::::::::::: ::::::::::::::::::::::::::::::: XP_011 MVLSQRQRDELDWFQRGEDSILNKADEARNRAIADYLRSNGYEEAYSVFKKEAELDVNEE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB3 LDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKY 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB3 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB3 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB3 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB3 SWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVR 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB3 GVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQ 370 380 390 400 410 420 410 pF1KB3 TVKVWECR :::::::: XP_011 TVKVWECR >>XP_016880191 (OMIM: 601545,607432) PREDICTED: platelet (345 aa) initn: 2387 init1: 2387 opt: 2387 Z-score: 1792.0 bits: 340.3 E(85289): 4.5e-93 Smith-Waterman score: 2387; 100.0% identity (100.0% similar) in 345 aa overlap (66-410:1-345) 40 50 60 70 80 90 pF1KB3 ELDVNEELDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWI :::::::::::::::::::::::::::::: XP_016 MELESKLNEAKEEFTSGGPLGQKRDPKEWI 10 20 30 100 110 120 130 140 150 pF1KB3 PRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQD 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB3 ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKT 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB3 IKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREH 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB3 EHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLV 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB3 GHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYV 280 290 300 310 320 330 400 410 pF1KB3 VTGSVDQTVKVWECR ::::::::::::::: XP_016 VTGSVDQTVKVWECR 340 >>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta (334 aa) initn: 855 init1: 437 opt: 475 Z-score: 374.8 bits: 78.0 E(85289): 3.9e-14 Smith-Waterman score: 648; 30.5% identity (62.5% similar) in 347 aa overlap (67-408:5-331) 40 50 60 70 80 90 pF1KB3 LDVNEELDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIP : . . . :. . : .. :.. : : XP_005 MATEEKKPETEAARAQPTPSSSATQSK-PTPVKP 10 20 30 100 110 120 130 140 150 pF1KB3 RPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDI :..:.:: . :. : : : ..:.: : ::.: : ::.:..:: ...:. XP_005 NYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB3 SFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTI ... ...::.: : : :.:.:: .. .:..:..::.. : . :... :::.: :... XP_005 AWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESV 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB3 KMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE ..:.:.:: :.::. .: . : :. :.::.::.: : : :.: .:. .: : . . XP_005 RIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDD 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB3 HVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG . : :. ..: : ..:... :.:.:.:: : : :: : .: XP_005 N--------PPVSFVKFSPN-----------GKYILAATLDNTLKLWDYSKGKCLKTYTG 220 230 240 250 340 350 360 370 380 390 pF1KB3 HDNWVRGVLFH---SGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAP : : .. . .:::.:.: ..:. . .:. ..:. .. :..: : : : : XP_005 HKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTEN 260 270 280 290 300 310 400 410 pF1KB3 YVVTGSV--DQTVKVWECR ...... :.:.:.:. XP_005 IIASAALENDKTIKLWKSDC 320 330 >>NP_438172 (OMIM: 609012) WD repeat-containing protein (334 aa) initn: 855 init1: 437 opt: 475 Z-score: 374.8 bits: 78.0 E(85289): 3.9e-14 Smith-Waterman score: 648; 30.5% identity (62.5% similar) in 347 aa overlap (67-408:5-331) 40 50 60 70 80 90 pF1KB3 LDVNEELDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIP : . . . :. . : .. :.. : : NP_438 MATEEKKPETEAARAQPTPSSSATQSK-PTPVKP 10 20 30 100 110 120 130 140 150 pF1KB3 RPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDI :..:.:: . :. : : : ..:.: : ::.: : ::.:..:: ...:. NP_438 NYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB3 SFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTI ... ...::.: : : :.:.:: .. .:..:..::.. : . :... :::.: :... NP_438 AWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESV 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB3 KMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE ..:.:.:: :.::. .: . : :. :.::.::.: : : :.: .:. .: : . . NP_438 RIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDD 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB3 HVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG . : :. ..: : ..:... :.:.:.:: : : :: : .: NP_438 N--------PPVSFVKFSPN-----------GKYILAATLDNTLKLWDYSKGKCLKTYTG 220 230 240 250 340 350 360 370 380 390 pF1KB3 HDNWVRGVLFH---SGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAP : : .. . .:::.:.: ..:. . .:. ..:. .. :..: : : : : NP_438 HKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTEN 260 270 280 290 300 310 400 410 pF1KB3 YVVTGSV--DQTVKVWECR ...... :.:.:.:. NP_438 IIASAALENDKTIKLWKSDC 320 330 410 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:08:22 2016 done: Fri Nov 4 02:08:24 2016 Total Scan time: 8.260 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]