FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3086, 580 aa 1>>>pF1KB3086 580 - 580 aa - 580 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2744+/-0.000764; mu= 15.7755+/- 0.047 mean_var=98.1457+/-19.330, 0's: 0 Z-trim(111.1): 10 B-trim: 0 in 0/53 Lambda= 0.129461 statistics sampled from 12126 (12135) to 12126 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.373), width: 16 Scan time: 3.650 The best scores are: opt bits E(32554) CCDS14638.1 GPC3 gene_id:2719|Hs108|chrX ( 580) 3923 742.9 2.5e-214 CCDS55495.1 GPC3 gene_id:2719|Hs108|chrX ( 526) 3145 597.6 1.3e-170 CCDS55496.1 GPC3 gene_id:2719|Hs108|chrX ( 603) 2336 446.5 4.4e-125 CCDS9468.1 GPC5 gene_id:2262|Hs108|chr13 ( 572) 1524 294.9 1.9e-79 CCDS9469.1 GPC6 gene_id:10082|Hs108|chr13 ( 555) 687 138.5 2.1e-32 CCDS2534.1 GPC1 gene_id:2817|Hs108|chr2 ( 558) 632 128.2 2.6e-29 CCDS14637.1 GPC4 gene_id:2239|Hs108|chrX ( 556) 591 120.6 5.3e-27 CCDS5689.1 GPC2 gene_id:221914|Hs108|chr7 ( 579) 457 95.6 1.9e-19 >>CCDS14638.1 GPC3 gene_id:2719|Hs108|chrX (580 aa) initn: 3923 init1: 3923 opt: 3923 Z-score: 3961.4 bits: 742.9 E(32554): 2.5e-214 Smith-Waterman score: 3923; 100.0% identity (100.0% similar) in 580 aa overlap (1-580:1-580) 10 20 30 40 50 60 pF1KB3 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 GRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQ 490 500 510 520 530 540 550 560 570 580 pF1KB3 QATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH :::::::::::::::::::::::::::::::::::::::: CCDS14 QATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH 550 560 570 580 >>CCDS55495.1 GPC3 gene_id:2719|Hs108|chrX (526 aa) initn: 3553 init1: 3145 opt: 3145 Z-score: 3176.7 bits: 597.6 E(32554): 1.3e-170 Smith-Waterman score: 3449; 90.7% identity (90.7% similar) in 580 aa overlap (1-580:1-526) 10 20 30 40 50 60 pF1KB3 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVP-- 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR :::::::: CCDS55 ----------------------------------------------------EAFEIVVR 60 130 140 150 160 170 180 pF1KB3 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT 70 80 90 100 110 120 190 200 210 220 230 240 pF1KB3 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB3 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI 190 200 210 220 230 240 310 320 330 340 350 360 pF1KB3 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA 250 260 270 280 290 300 370 380 390 400 410 420 pF1KB3 YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT 310 320 330 340 350 360 430 440 450 460 470 480 pF1KB3 LCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPK 370 380 390 400 410 420 490 500 510 520 530 540 pF1KB3 GRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQ 430 440 450 460 470 480 550 560 570 580 pF1KB3 QATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH :::::::::::::::::::::::::::::::::::::::: CCDS55 QATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH 490 500 510 520 >>CCDS55496.1 GPC3 gene_id:2719|Hs108|chrX (603 aa) initn: 2336 init1: 2336 opt: 2336 Z-score: 2359.2 bits: 446.5 E(32554): 4.4e-125 Smith-Waterman score: 3867; 96.2% identity (96.2% similar) in 603 aa overlap (1-580:1-603) 10 20 30 40 50 60 pF1KB3 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI 250 260 270 280 290 300 310 320 330 340 pF1KB3 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTT---------------- :::::::::::::::::::::::::::::::::::::::::::: CCDS55 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTETEKKIWHFKYPIFFL 310 320 330 340 350 360 350 360 370 380 390 pF1KB3 -------IGKLCAHSQQRQYRSAYYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKS ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 CIGLDLQIGKLCAHSQQRQYRSAYYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKS 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB3 FISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 FISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEP 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB3 VVSQIIDKLKHINQLLRTMSMPKGRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VVSQIIDKLKHINQLLRTMSMPKGRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVK 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB3 NQLRFLAELAYDLDVDDAPGNSQQATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 NQLRFLAELAYDLDVDDAPGNSQQATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFF 550 560 570 580 590 600 580 pF1KB3 LVH ::: CCDS55 LVH >>CCDS9468.1 GPC5 gene_id:2262|Hs108|chr13 (572 aa) initn: 1570 init1: 1432 opt: 1524 Z-score: 1539.9 bits: 294.9 E(32554): 1.9e-79 Smith-Waterman score: 1524; 44.9% identity (75.1% similar) in 515 aa overlap (34-543:29-539) 10 20 30 40 50 60 pF1KB3 TVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGSDL ::..::..:: :: ... .:..: : :: CCDS94 MDAQTWPVGFRCLLLLALVGSARSEGVQTCEEVRKLFQWRLLGAVRGLPDSPRAGPDL 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 QVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHA :::. : ::::.:::::.::..:: .:.:.::..: ::::: .:::.:::..: ....: CCDS94 QVCISKKPTCCTRKMEERYQIAARQDMQQFLQTSSSTLKFLISRNAAAFQETLETLIKQA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 KNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQL .:::. .: ..: ... .: : ::::::.::..:.:.: ...::..::::::..:..: CCDS94 ENYTSILFCSTYRNMALEAAASVQEFFTDVGLYLFGADVNPEEFVNRFFDSLFPLVYNHL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 MNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINT .:::. ::.:. .::.: ::::.. :::.:. .: :...:: .: :::::::::::::: CCDS94 INPGVTDSSLEYSECIRMARRDVSPFGNIPQRVMGQMGRSLLPSRTFLQALNLGIEVINT 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 TDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILS ::.:.:::.:.: : .: :: .:::: ..::: ::: ::.::.: ..:.. .:. :: : CCDS94 TDYLHFSKECSRALLKMQYCPHCQGLALTKPCMGYCLNVMRGCLAHMAELNPHWHAYIRS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB3 LEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYY :::: ..:. ::. .:::.. ..:.. .. :. :: ....:.. . .: CCDS94 LEELSDAMHGTYDIGHVLLNFHLLVNDAVLQAHLNGQKLLEQVNRICGRPVRTPTQSPRC 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB3 PEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDTLC : .:. .:.. . ::::..::.:.:..:. . :::..: .:.. .: . : CCDS94 SFDQSKEKHGMKTTTRNSEETLANRRKEFINSLRLYRSFYGGLADQLCANELAAADGLPC 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB3 WNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLL--RTMSMPK :::...:. :.:... ::.: : . :.:.:: .::..::::::::. ::: :. . : CCDS94 WNGEDIVKSYTQRVVGNGIKAQSGNPEVKVKGIDPVINQIIDKLKHVVQLLQGRSPKPDK 420 430 440 450 460 470 490 500 510 520 530 pF1KB3 GRVLDKNLDEEGFE--SGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGN ..:. . : :::: :::: : ::::.: .:: :.. . :.. .:. CCDS94 WELLQLGSGGGMVEQVSGDC-DDEDGC-GGSGSG--EVKRTLKITDWMPDDMNFSDVKQI 480 490 500 510 520 530 540 550 560 570 580 pF1KB3 SQQATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH : : CCDS94 HQTDTGSTLDTTGAGCAVATESMTFTLISVVMLLPGIW 540 550 560 570 >>CCDS9469.1 GPC6 gene_id:10082|Hs108|chr13 (555 aa) initn: 609 init1: 338 opt: 687 Z-score: 695.2 bits: 138.5 E(32554): 2.1e-32 Smith-Waterman score: 690; 27.8% identity (59.3% similar) in 482 aa overlap (34-501:29-504) 10 20 30 40 50 60 pF1KB3 TVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQ .: .::. . .: .: . : :. CCDS94 MPSWIGAVILPLLGLLLSLPAGADVKARSCGEVRQAYGAKGFSLADIPYQEIAGEHLR 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 VCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHAK .: :. :::. .::.: . ..:..:.:.. .: .. ... :.: :. ....:. CCDS94 IC-PQEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 NYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQLM . : :: .: : : : ..::... : :...:...:.:... :. .. ::. CCDS94 KSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMF-QLI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 NPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINTT :: : : ::. .:: ::. :. . ::.... ..: :.:.:..: :: : . CCDS94 NPQYHFSE-DYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 DHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSL .... . : : : .: :: ::.:: :.::..:: ::.::.:. ...: : .: .. CCDS94 SKVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDTEWNLFIDAM 240 250 260 270 280 290 310 320 330 340 350 pF1KB3 EELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQ----RQYRS ... . ...:.:. . : ..:. .:.:. .... . . :.. . :. :: CCDS94 LLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARS 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 AYYPEDL---FIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVA : ::.. : . . . .:. .. .::: . .:::: ::. :. CCDS94 A--PENFNTRFRPYNPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDESVT 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 E---NDTLCWNGQELVERYSQKAARNGMKNQFNLHELK--MKGPEPVVSQIIDKLKHINQ :. ::::. . :: . .:. ::.: :. . :. . : : :. ... CCDS94 AGTSNEEECWNGHSKA-RYLPEIMNDGLTNQINNPEVDVDITRPDTFIRQQIMALRVMTN 420 430 440 450 460 470 480 490 500 510 520 pF1KB3 LLRTMSMPKGRVLDKNLDEE-GFESGD-CGDDEDECIGGSGDGMIKVKNQLRFLAELAYD :.. . .. . :: : ::. : :: CCDS94 KLKNAYNGNDVNFQDTSDESSGSGSGSGCMDDVCPTEFEFVTTEAPAVDPDRREVDSSAA 480 490 500 510 520 530 530 540 550 560 570 580 pF1KB3 LDVDDAPGNSQQATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH CCDS94 QRGHSLLSWSLTCIVLALQRLCR 540 550 >>CCDS2534.1 GPC1 gene_id:2817|Hs108|chr2 (558 aa) initn: 490 init1: 286 opt: 632 Z-score: 639.7 bits: 128.2 E(32554): 2.6e-29 Smith-Waterman score: 632; 25.0% identity (59.0% similar) in 488 aa overlap (24-501:21-497) 10 20 30 40 50 60 pF1KB3 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS :. : . .: .::... .:. ::.. . : CCDS25 MELRARGWWLLCAAAALVACARGDPASKSRSCGEVRQIYGAKGFSLSDVPQAEISGE 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR :..: :.: :::. .:::. .. ..: :...: :. .. . :.. :. .. CCDS25 HLRIC-PQGYTCCTSEMEENLANRSHAELETALRDSSRVLQAMLATQLRSFDDHFQHLLN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT .. .: : . . : : . ...... :: :....... . :.. :. .. CCDS25 DSERTLQATFPGAFGELYTQNARAFRDLYSELRLYYRGANLHLEETLAEFWARLLERLFK 120 130 140 150 160 170 190 200 210 220 230 pF1KB3 QLMNPGL--PDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIE :: .: : ::. :: :: . :. ::. :. . ...... ..: :.:.:... . CCDS25 QL-HPQLLLPDDYLD---CLGKQAEALRPFGEAPRELRLRATRAFVAARSFVQGLGVASD 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 VINTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWRE :. . .. .. .:.: . .. ::..: :. ..:: :: :..::.:. ...: ::. CCDS25 VVRKVAQVPLGPECSRAVMKLVYCAHCLGVPGARPCPDYCRNVLKGCLANQADLDAEWRN 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 YILSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYR . :. ... .. .:.:. .. . . ..:. .: : ::. . . :.. . CCDS25 LLDSMVLITDKFWGTSGVESVIGSVHTWLAEAINALQDNRDTLTAKVIQGCGNPKVNPQG 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 SAYYPEDLFIDKKVLKVAHVEHEE--TLSSRRRELIQKLKSFISFYSALPGYICSHSPV- . ::. .. :.: :. :: . : .:.. .:. .::: .::.. . CCDS25 PG--PEE---KRRRGKLAPRERPPSGTLEKLVSEAKAQLRDVQDFWISLPGTLCSEKMAL 360 370 380 390 400 420 430 440 450 460 470 pF1KB3 -AENDTLCWNGQELVERYSQKAARNGMKNQFNLHELK--MKGPEPVVSQIIDKLKHINQL . .: ::::. :: .. .:. ::.: :.. . :. .. : : .:: ... CCDS25 STASDDRCWNGMAR-GRYLPEVMGDGLANQINNPEVEVDITKPDMTIRQQIMQLKIMTNR 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB3 LRTMSMPKG-RVLDKNLDEEGFESGD-CGDDEDECIGGSGDGMIKVKNQLRFLAELAYDL ::. . : . : : ::: : :: CCDS25 LRSAYNGNDVDFQDASDDGSGSGSGDGCLDDLCSRKVSRKSSSSRTPLTHALPGLSEQEG 470 480 490 500 510 520 540 550 560 570 580 pF1KB3 DVDDAPGNSQQATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH CCDS25 QKTSAASCPQPPTFLLPLLLFLALTVARPRWR 530 540 550 >>CCDS14637.1 GPC4 gene_id:2239|Hs108|chrX (556 aa) initn: 421 init1: 256 opt: 591 Z-score: 598.3 bits: 120.6 E(32554): 5.3e-27 Smith-Waterman score: 636; 26.9% identity (60.7% similar) in 494 aa overlap (34-512:29-501) 10 20 30 40 50 60 pF1KB3 TVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQ .: .:: .. . . .: . :. :. CCDS14 MARFGLPALLCTLAVLSAALLAAELKSKSCSEVRRLYVSKGFNKNDAPLHEINGDHLK 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 VCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHAK .: :.: ::::..:::::.: .. ....... .:. .. . :.: :. ....:. CCDS14 IC-PQGSTCCSQEMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 NYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQLM . : :: ..: : : :. ..:.... : . ...:...:.:... :. .. .:. CCDS14 KSLNDMFVKTYGHLYMQNSELFKDLFVELKRYYVVGNVNLEEMLNDFWARLLERMF-RLV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 NPG--LPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVIN : . : : ::. ..:: ::. :. . ::.... ..: : :.: .. .:.. CCDS14 NSQYHFTDEYL---ECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVAGDVVS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 TTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYIL .. .. . .: . : .: :::.:.::. :::: .::. .:.::.:. ..: : ..: CCDS14 KVSVVNPTAQCTHALLKMIYCSHCRGLVTVKPCYNYCSNIMRGCLANQGDLDFEWNNFID 240 250 260 270 280 290 310 320 330 340 350 pF1KB3 SLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQ----RQY .. ... . ...:.:. . : :.:. .: :. ... . . :. . : CCDS14 AMLMVAERLEGPFNIESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGCGPPKPLPAGRIS 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 RSAYYPEDLFIDKKVLKVAHVEHEETL---SSRRR---ELIQKLKSFISFYSALPGYICS :: :. : . .. : :.. : .: : .. .:::. .:.:.::. .:. CCDS14 RSI--SESAFSAR--FRPHHPEERPTTAAGTSLDRLVTDVKEKLKQAKKFWSSLPSNVCN 360 370 380 390 400 420 430 440 450 460 pF1KB3 HSPVAE---NDTLCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKH .: :. ::::. :: .. ::. :: : :... .: . .: :.. CCDS14 DERMAAGNGNEDDCWNGKGK-SRYLFAVTGNGLANQGNNPEVQVDTSKPDI--LI--LRQ 410 420 430 440 450 460 470 480 490 500 510 520 pF1KB3 INQLLRTMSMPKGRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAY : . ::.:. . . : : . :. .: .. : :::.: CCDS14 I-MALRVMTSKMKNAYNGN-DVDFFDISDESSGE-----GSGSGCEYQQCPSEFDYNATD 470 480 490 500 510 530 540 550 560 570 580 pF1KB3 DLDVDDAPGNSQQATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH CCDS14 HAGKSANEKADSAGVRPGAQAYLLTVFCILFLVMQREWR 520 530 540 550 >>CCDS5689.1 GPC2 gene_id:221914|Hs108|chr7 (579 aa) initn: 103 init1: 71 opt: 457 Z-score: 462.8 bits: 95.6 E(32554): 1.9e-19 Smith-Waterman score: 490; 24.3% identity (54.1% similar) in 518 aa overlap (15-512:7-505) 10 20 30 40 50 pF1KB3 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDA-----TCHQVRSFFQRLQPGLKWVPET :: : .: : : : . .: ..:. . .:. .: . CCDS56 MSALRPLLLLLLPLCPGPGPGPGSEAKVTRSCAETRQVLGARGYSLNLIPPA 10 20 30 40 50 60 70 80 90 100 110 pF1KB3 PVPGSDLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAF . : :.:: :. :::: . :.. .. ... :..... : . :.: : CCDS56 LISGEHLRVC-PQEYTCCSSETEQRLIRETEATFRGLVEDSGSFLVHTLAARHRKFDEFF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 EIVVRHAKNYTNAMFKNNYPSLTPQ-AFEFVGEFFTDVSLYIL---GSDINVDDMVNELF .. :.. . .:...: : : :. : : : ..: : : .. :. .:. CCDS56 LEMLSVAQHSLTQLFSHSYGRLYAQHALIFNGLFSRLRDFYGESGEGLDDTLADFWAQLL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 DSLFPVIYTQLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQ . .::... : : :: : ... .. .:. ::. :. . :....: ..: :.: CCDS56 ERVFPLLHPQYSFP--PDYLLCLSRLASSTDGSLQPFGDSPRRLRLQITRTLVAARAFVQ 180 190 200 210 220 240 250 260 270 280 290 pF1KB3 ALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGV-V .:. : .:.. . .. :. :.. : :. : :.:. . :: :.: :..::... . CCDS56 GLETGRNVVSEALKVPVSEGCSQALMRLIGCPLCRGVPSLMPCQGFCLNVVRGCLSSRGL 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB3 EIDKYWREYILSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCA : : : .:. .: :.. . ...: . .. : ....:.:.:..:... . . :. CCDS56 EPD--WGNYLDGLLILADKLQGPFSFELTAESIGVKISEGLMYLQENSAKVSAQVFQECG 290 300 310 320 330 340 360 370 380 390 400 pF1KB3 HSQQRQYRSAYYPEDLFIDKKVLKVAHVEHEETLSSRRR------ELIQKLKSFISFYSA . :. : .. ... :.. : .. :: ..: . .:.. CCDS56 PPDPVPARNRRAPPPREEAGRLWSMVTEEERPTTAAGTNLHRLVWELRERLARMRGFWAR 350 360 370 380 390 400 410 420 430 440 450 460 pF1KB3 LPGYICSHSPVAENDTL----CWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVS : .:. : .: . .: ::.: :: .. .. .: : :::. . : : CCDS56 LSLTVCGDSRMAADASLEAAPCWTGAGR-GRYLPPVVGGSPAEQVNNPELKVDASGPDVP 410 420 430 440 450 460 470 480 490 500 510 520 pF1KB3 QIIDKLKHINQLLRTMSMPKGRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQL .: :: . . : .: ..:: :.: :: .::: : CCDS56 TRRRRL----QLRAATARMKTAALGHDLD---------GQDADEDASGSGGGQQYADDWM 470 480 490 500 510 530 540 550 560 570 580 pF1KB3 RFLAELAYDLDVDDAPGNSQQATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH CCDS56 AGAVAPPARPPRPPYPPRRDGSGGKGGGGSARYNQGRSRSGGASIGFHTQTILILSLSAL 520 530 540 550 560 570 580 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:24:59 2016 done: Fri Nov 4 23:25:00 2016 Total Scan time: 3.650 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]