Result of FASTA (omim) for
pF1KB3086
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3086, 580 aa
1>>>pF1KB3086 580 - 580 aa - 580 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5924+/-0.000317; mu= 13.6849+/- 0.020
mean_var=95.9170+/-18.746, 0's: 0 Z-trim(118.9): 32 B-trim: 546 in 2/54
Lambda= 0.130956
statistics sampled from 32303 (32335) to 32303 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.379), width: 16
Scan time: 11.010
The best scores are: opt bits E(85289)
NP_004475 (OMIM: 194070,300037,312870) glypican-3 ( 580) 3923 751.3 2e-216
NP_001158091 (OMIM: 194070,300037,312870) glypican ( 526) 3145 604.2 3.3e-172
NP_001158090 (OMIM: 194070,300037,312870) glypican ( 564) 3145 604.3 3.5e-172
XP_016884902 (OMIM: 194070,300037,312870) PREDICTE ( 486) 2940 565.5 1.4e-160
NP_001158089 (OMIM: 194070,300037,312870) glypican ( 603) 2336 451.4 3.8e-126
NP_004457 (OMIM: 602446) glypican-5 precursor [Hom ( 572) 1524 298.0 5.5e-80
XP_016875924 (OMIM: 602446) PREDICTED: glypican-5 ( 565) 1513 295.9 2.3e-79
XP_011519356 (OMIM: 602446) PREDICTED: glypican-5 ( 480) 1436 281.3 4.8e-75
XP_011519362 (OMIM: 602446) PREDICTED: glypican-5 ( 443) 1301 255.8 2.1e-67
XP_011519357 (OMIM: 602446) PREDICTED: glypican-5 ( 444) 1294 254.5 5.4e-67
XP_011519358 (OMIM: 602446) PREDICTED: glypican-5 ( 444) 1294 254.5 5.4e-67
XP_016875926 (OMIM: 602446) PREDICTED: glypican-5 ( 444) 1294 254.5 5.4e-67
XP_011519361 (OMIM: 602446) PREDICTED: glypican-5 ( 444) 1294 254.5 5.4e-67
XP_011519359 (OMIM: 602446) PREDICTED: glypican-5 ( 444) 1294 254.5 5.4e-67
XP_011519360 (OMIM: 602446) PREDICTED: glypican-5 ( 444) 1294 254.5 5.4e-67
XP_016875925 (OMIM: 602446) PREDICTED: glypican-5 ( 444) 1294 254.5 5.4e-67
NP_005699 (OMIM: 258315,604404) glypican-6 precurs ( 555) 687 139.9 2.2e-32
NP_002072 (OMIM: 600395) glypican-1 precursor [Hom ( 558) 632 129.5 2.9e-29
XP_016875787 (OMIM: 258315,604404) PREDICTED: glyp ( 485) 604 124.2 1e-27
XP_016875788 (OMIM: 258315,604404) PREDICTED: glyp ( 485) 604 124.2 1e-27
XP_011519346 (OMIM: 258315,604404) PREDICTED: glyp ( 485) 604 124.2 1e-27
XP_016875789 (OMIM: 258315,604404) PREDICTED: glyp ( 485) 604 124.2 1e-27
NP_001439 (OMIM: 194070,300168,312870) glypican-4 ( 556) 591 121.7 6.2e-27
XP_016875790 (OMIM: 258315,604404) PREDICTED: glyp ( 433) 540 112.0 4e-24
XP_011509278 (OMIM: 600395) PREDICTED: glypican-1 ( 486) 520 108.3 6.1e-23
XP_016875791 (OMIM: 258315,604404) PREDICTED: glyp ( 324) 162 40.6 0.0098
>>NP_004475 (OMIM: 194070,300037,312870) glypican-3 isof (580 aa)
initn: 3923 init1: 3923 opt: 3923 Z-score: 4006.4 bits: 751.3 E(85289): 2e-216
Smith-Waterman score: 3923; 100.0% identity (100.0% similar) in 580 aa overlap (1-580:1-580)
10 20 30 40 50 60
pF1KB3 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 LCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 GRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQ
490 500 510 520 530 540
550 560 570 580
pF1KB3 QATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH
::::::::::::::::::::::::::::::::::::::::
NP_004 QATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH
550 560 570 580
>>NP_001158091 (OMIM: 194070,300037,312870) glypican-3 i (526 aa)
initn: 3553 init1: 3145 opt: 3145 Z-score: 3212.7 bits: 604.2 E(85289): 3.3e-172
Smith-Waterman score: 3449; 90.7% identity (90.7% similar) in 580 aa overlap (1-580:1-526)
10 20 30 40 50 60
pF1KB3 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVP--
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR
::::::::
NP_001 ----------------------------------------------------EAFEIVVR
60
130 140 150 160 170 180
pF1KB3 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT
70 80 90 100 110 120
190 200 210 220 230 240
pF1KB3 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB3 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB3 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA
250 260 270 280 290 300
370 380 390 400 410 420
pF1KB3 YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT
310 320 330 340 350 360
430 440 450 460 470 480
pF1KB3 LCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPK
370 380 390 400 410 420
490 500 510 520 530 540
pF1KB3 GRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQ
430 440 450 460 470 480
550 560 570 580
pF1KB3 QATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH
::::::::::::::::::::::::::::::::::::::::
NP_001 QATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH
490 500 510 520
>>NP_001158090 (OMIM: 194070,300037,312870) glypican-3 i (564 aa)
initn: 3808 init1: 3140 opt: 3145 Z-score: 3212.2 bits: 604.3 E(85289): 3.5e-172
Smith-Waterman score: 3780; 97.1% identity (97.2% similar) in 580 aa overlap (1-580:1-564)
10 20 30 40 50 60
pF1KB3 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR
:::::::::::::::::::::::::::::::::::: .:::::::
NP_001 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSA----------------KAFEIVVR
70 80 90 100
130 140 150 160 170 180
pF1KB3 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB3 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB3 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB3 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB3 YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB3 LCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPK
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB3 GRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQ
470 480 490 500 510 520
550 560 570 580
pF1KB3 QATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH
::::::::::::::::::::::::::::::::::::::::
NP_001 QATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH
530 540 550 560
>>XP_016884902 (OMIM: 194070,300037,312870) PREDICTED: g (486 aa)
initn: 2940 init1: 2940 opt: 2940 Z-score: 3003.9 bits: 565.5 E(85289): 1.4e-160
Smith-Waterman score: 2940; 99.8% identity (99.8% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KB3 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 LCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPK
:::::::::::: ::
XP_016 LCWNGQELVERYIQKNTEEPFLPLFTTYSRDATQEKNPPGTLFPVSDLPLSQTCLESVKS
430 440 450 460 470 480
>>NP_001158089 (OMIM: 194070,300037,312870) glypican-3 i (603 aa)
initn: 2336 init1: 2336 opt: 2336 Z-score: 2385.7 bits: 451.4 E(85289): 3.8e-126
Smith-Waterman score: 3867; 96.2% identity (96.2% similar) in 603 aa overlap (1-580:1-603)
10 20 30 40 50 60
pF1KB3 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI
250 260 270 280 290 300
310 320 330 340
pF1KB3 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTT----------------
::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTETEKKIWHFKYPIFFL
310 320 330 340 350 360
350 360 370 380 390
pF1KB3 -------IGKLCAHSQQRQYRSAYYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIGLDLQIGKLCAHSQQRQYRSAYYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKS
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB3 FISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEP
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB3 VVSQIIDKLKHINQLLRTMSMPKGRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVSQIIDKLKHINQLLRTMSMPKGRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVK
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB3 NQLRFLAELAYDLDVDDAPGNSQQATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQLRFLAELAYDLDVDDAPGNSQQATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFF
550 560 570 580 590 600
580
pF1KB3 LVH
:::
NP_001 LVH
>>NP_004457 (OMIM: 602446) glypican-5 precursor [Homo sa (572 aa)
initn: 1570 init1: 1432 opt: 1524 Z-score: 1557.0 bits: 298.0 E(85289): 5.5e-80
Smith-Waterman score: 1524; 44.9% identity (75.1% similar) in 515 aa overlap (34-543:29-539)
10 20 30 40 50 60
pF1KB3 TVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGSDL
::..::..:: :: ... .:..: : ::
NP_004 MDAQTWPVGFRCLLLLALVGSARSEGVQTCEEVRKLFQWRLLGAVRGLPDSPRAGPDL
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 QVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHA
:::. : ::::.:::::.::..:: .:.:.::..: ::::: .:::.:::..: ....:
NP_004 QVCISKKPTCCTRKMEERYQIAARQDMQQFLQTSSSTLKFLISRNAAAFQETLETLIKQA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 KNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQL
.:::. .: ..: ... .: : ::::::.::..:.:.: ...::..::::::..:..:
NP_004 ENYTSILFCSTYRNMALEAAASVQEFFTDVGLYLFGADVNPEEFVNRFFDSLFPLVYNHL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 MNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINT
.:::. ::.:. .::.: ::::.. :::.:. .: :...:: .: ::::::::::::::
NP_004 INPGVTDSSLEYSECIRMARRDVSPFGNIPQRVMGQMGRSLLPSRTFLQALNLGIEVINT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 TDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILS
::.:.:::.:.: : .: :: .:::: ..::: ::: ::.::.: ..:.. .:. :: :
NP_004 TDYLHFSKECSRALLKMQYCPHCQGLALTKPCMGYCLNVMRGCLAHMAELNPHWHAYIRS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 LEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYY
:::: ..:. ::. .:::.. ..:.. .. :. :: ....:.. . .:
NP_004 LEELSDAMHGTYDIGHVLLNFHLLVNDAVLQAHLNGQKLLEQVNRICGRPVRTPTQSPRC
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 PEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDTLC
: .:. .:.. . ::::..::.:.:..:. . :::..: .:.. .: . :
NP_004 SFDQSKEKHGMKTTTRNSEETLANRRKEFINSLRLYRSFYGGLADQLCANELAAADGLPC
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 WNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLL--RTMSMPK
:::...:. :.:... ::.: : . :.:.:: .::..::::::::. ::: :. . :
NP_004 WNGEDIVKSYTQRVVGNGIKAQSGNPEVKVKGIDPVINQIIDKLKHVVQLLQGRSPKPDK
420 430 440 450 460 470
490 500 510 520 530
pF1KB3 GRVLDKNLDEEGFE--SGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGN
..:. . : :::: :::: : ::::.: .:: :.. . :.. .:.
NP_004 WELLQLGSGGGMVEQVSGDC-DDEDGC-GGSGSG--EVKRTLKITDWMPDDMNFSDVKQI
480 490 500 510 520 530
540 550 560 570 580
pF1KB3 SQQATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH
: :
NP_004 HQTDTGSTLDTTGAGCAVATESMTFTLISVVMLLPGIW
540 550 560 570
>>XP_016875924 (OMIM: 602446) PREDICTED: glypican-5 isof (565 aa)
initn: 1570 init1: 1432 opt: 1513 Z-score: 1545.8 bits: 295.9 E(85289): 2.3e-79
Smith-Waterman score: 1513; 46.2% identity (76.8% similar) in 487 aa overlap (34-515:29-513)
10 20 30 40 50 60
pF1KB3 TVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGSDL
::..::..:: :: ... .:..: : ::
XP_016 MDAQTWPVGFRCLLLLALVGSARSEGVQTCEEVRKLFQWRLLGAVRGLPDSPRAGPDL
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 QVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHA
:::. : ::::.:::::.::..:: .:.:.::..: ::::: .:::.:::..: ....:
XP_016 QVCISKKPTCCTRKMEERYQIAARQDMQQFLQTSSSTLKFLISRNAAAFQETLETLIKQA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 KNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQL
.:::. .: ..: ... .: : ::::::.::..:.:.: ...::..::::::..:..:
XP_016 ENYTSILFCSTYRNMALEAAASVQEFFTDVGLYLFGADVNPEEFVNRFFDSLFPLVYNHL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 MNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINT
.:::. ::.:. .::.: ::::.. :::.:. .: :...:: .: ::::::::::::::
XP_016 INPGVTDSSLEYSECIRMARRDVSPFGNIPQRVMGQMGRSLLPSRTFLQALNLGIEVINT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 TDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILS
::.:.:::.:.: : .: :: .:::: ..::: ::: ::.::.: ..:.. .:. :: :
XP_016 TDYLHFSKECSRALLKMQYCPHCQGLALTKPCMGYCLNVMRGCLAHMAELNPHWHAYIRS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 LEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYY
:::: ..:. ::. .:::.. ..:.. .. :. :: ....:.. . .:
XP_016 LEELSDAMHGTYDIGHVLLNFHLLVNDAVLQAHLNGQKLLEQVNRICGRPVRTPTQSPRC
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 PEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDTLC
: .:. .:.. . ::::..::.:.:..:. . :::..: .:.. .: . :
XP_016 SFDQSKEKHGMKTTTRNSEETLANRRKEFINSLRLYRSFYGGLADQLCANELAAADGLPC
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 WNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLL--RTMSMPK
:::...:. :.:... ::.: : . :.:.:: .::..::::::::. ::: :. . :
XP_016 WNGEDIVKSYTQRVVGNGIKAQSGNPEVKVKGIDPVINQIIDKLKHVVQLLQGRSPKPDK
420 430 440 450 460 470
490 500 510 520 530
pF1KB3 GRVLDKNLDEEGFE--SGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGN
..:. . : :::: :::: : ::::.: .:
XP_016 WELLQLGSGGGMVEQVSGDC-DDEDGC-GGSGSGEVKRTLKITDSRGWFTELCSLITATS
480 490 500 510 520 530
540 550 560 570 580
pF1KB3 SQQATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH
XP_016 NEVGLNIFPVLPTDRKGRLNKNTPNGAFE
540 550 560
>>XP_011519356 (OMIM: 602446) PREDICTED: glypican-5 isof (480 aa)
initn: 1434 init1: 1400 opt: 1436 Z-score: 1468.3 bits: 281.3 E(85289): 4.8e-75
Smith-Waterman score: 1436; 46.5% identity (78.6% similar) in 439 aa overlap (34-471:29-467)
10 20 30 40 50 60
pF1KB3 TVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGSDL
::..::..:: :: ... .:..: : ::
XP_011 MDAQTWPVGFRCLLLLALVGSARSEGVQTCEEVRKLFQWRLLGAVRGLPDSPRAGPDL
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 QVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHA
:::. : ::::.:::::.::..:: .:.:.::..: ::::: .:::.:::..: ....:
XP_011 QVCISKKPTCCTRKMEERYQIAARQDMQQFLQTSSSTLKFLISRNAAAFQETLETLIKQA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 KNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQL
.:::. .: ..: ... .: : ::::::.::..:.:.: ...::..::::::..:..:
XP_011 ENYTSILFCSTYRNMALEAAASVQEFFTDVGLYLFGADVNPEEFVNRFFDSLFPLVYNHL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 MNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINT
.:::. ::.:. .::.: ::::.. :::.:. .: :...:: .: ::::::::::::::
XP_011 INPGVTDSSLEYSECIRMARRDVSPFGNIPQRVMGQMGRSLLPSRTFLQALNLGIEVINT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 TDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILS
::.:.:::.:.: : .: :: .:::: ..::: ::: ::.::.: ..:.. .:. :: :
XP_011 TDYLHFSKECSRALLKMQYCPHCQGLALTKPCMGYCLNVMRGCLAHMAELNPHWHAYIRS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 LEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYY
:::: ..:. ::. .:::.. ..:.. .. :. :: ....:.. . .:
XP_011 LEELSDAMHGTYDIGHVLLNFHLLVNDAVLQAHLNGQKLLEQVNRICGRPVRTPTQSPRC
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 PEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDTLC
: .:. .:.. . ::::..::.:.:..:. . :::..: .:.. .: . :
XP_011 SFDQSKEKHGMKTTTRNSEETLANRRKEFINSLRLYRSFYGGLADQLCANELAAADGLPC
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 WNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPKGR
:::...:. :.:... ::.: : . :.:.:: .::..::::::::. :
XP_011 WNGEDIVKSYTQRVVGNGIKAQSGNPEVKVKGIDPVINQIIDKLKHVVQETNWKLFGMNH
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 VLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQQA
XP_011 LI
480
>>XP_011519362 (OMIM: 602446) PREDICTED: glypican-5 isof (443 aa)
initn: 1298 init1: 1264 opt: 1301 Z-score: 1331.0 bits: 255.8 E(85289): 2.1e-67
Smith-Waterman score: 1301; 45.4% identity (76.9% similar) in 412 aa overlap (34-444:29-440)
10 20 30 40 50 60
pF1KB3 TVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGSDL
::..::..:: :: ... .:..: : ::
XP_011 MDAQTWPVGFRCLLLLALVGSARSEGVQTCEEVRKLFQWRLLGAVRGLPDSPRAGPDL
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 QVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHA
:::. : ::::.:::::.::..:: .:.:.::..: ::::: .:::.:::..: ....:
XP_011 QVCISKKPTCCTRKMEERYQIAARQDMQQFLQTSSSTLKFLISRNAAAFQETLETLIKQA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 KNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQL
.:::. .: ..: ... .: : ::::::.::..:.:.: ...::..::::::..:..:
XP_011 ENYTSILFCSTYRNMALEAAASVQEFFTDVGLYLFGADVNPEEFVNRFFDSLFPLVYNHL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 MNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINT
.:::. ::.:. .::.: ::::.. :::.:. .: :...:: .: ::::::::::::::
XP_011 INPGVTDSSLEYSECIRMARRDVSPFGNIPQRVMGQMGRSLLPSRTFLQALNLGIEVINT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 TDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILS
::.:.:::.:.: : .: :: .:::: ..::: ::: ::.::.: ..:.. .:. :: :
XP_011 TDYLHFSKECSRALLKMQYCPHCQGLALTKPCMGYCLNVMRGCLAHMAELNPHWHAYIRS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 LEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYY
:::: ..:. ::. .:::.. ..:.. .. :. :: ....:.. . .:
XP_011 LEELSDAMHGTYDIGHVLLNFHLLVNDAVLQAHLNGQKLLEQVNRICGRPVRTPTQSPRC
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 PEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDTLC
: .:. .:.. . ::::..::.:.:..:. . :::..: .:.. .: . :
XP_011 SFDQSKEKHGMKTTTRNSEETLANRRKEFINSLRLYRSFYGGLADQLCANELAAADGLPC
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 WNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPKGR
:::...:.: : : :.
XP_011 WNGEDIVKRCEIWINRLLMTNHKLE
420 430 440
>>XP_011519357 (OMIM: 602446) PREDICTED: glypican-5 isof (444 aa)
initn: 1292 init1: 1258 opt: 1294 Z-score: 1323.8 bits: 254.5 E(85289): 5.4e-67
Smith-Waterman score: 1294; 45.8% identity (78.2% similar) in 400 aa overlap (34-432:29-428)
10 20 30 40 50 60
pF1KB3 TVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGSDL
::..::..:: :: ... .:..: : ::
XP_011 MDAQTWPVGFRCLLLLALVGSARSEGVQTCEEVRKLFQWRLLGAVRGLPDSPRAGPDL
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 QVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHA
:::. : ::::.:::::.::..:: .:.:.::..: ::::: .:::.:::..: ....:
XP_011 QVCISKKPTCCTRKMEERYQIAARQDMQQFLQTSSSTLKFLISRNAAAFQETLETLIKQA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 KNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQL
.:::. .: ..: ... .: : ::::::.::..:.:.: ...::..::::::..:..:
XP_011 ENYTSILFCSTYRNMALEAAASVQEFFTDVGLYLFGADVNPEEFVNRFFDSLFPLVYNHL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 MNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINT
.:::. ::.:. .::.: ::::.. :::.:. .: :...:: .: ::::::::::::::
XP_011 INPGVTDSSLEYSECIRMARRDVSPFGNIPQRVMGQMGRSLLPSRTFLQALNLGIEVINT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 TDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILS
::.:.:::.:.: : .: :: .:::: ..::: ::: ::.::.: ..:.. .:. :: :
XP_011 TDYLHFSKECSRALLKMQYCPHCQGLALTKPCMGYCLNVMRGCLAHMAELNPHWHAYIRS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 LEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYY
:::: ..:. ::. .:::.. ..:.. .. :. :: ....:.. . .:
XP_011 LEELSDAMHGTYDIGHVLLNFHLLVNDAVLQAHLNGQKLLEQVNRICGRPVRTPTQSPRC
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 PEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDTLC
: .:. .:.. . ::::..::.:.:..:. . :::..: .:.. .: . :
XP_011 SFDQSKEKHGMKTTTRNSEETLANRRKEFINSLRLYRSFYGGLADQLCANELAAADGLPC
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 WNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPKGR
:::...:. .
XP_011 WNGEDIVKSWQVSSWGDDGSKVRKKK
420 430 440
580 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:25:00 2016 done: Fri Nov 4 23:25:01 2016
Total Scan time: 11.010 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]