FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3092, 716 aa 1>>>pF1KB3092 716 - 716 aa - 716 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1853+/-0.000466; mu= 15.6209+/- 0.029 mean_var=86.1107+/-16.691, 0's: 0 Z-trim(110.7): 191 B-trim: 43 in 1/53 Lambda= 0.138212 statistics sampled from 18911 (19106) to 18911 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.57), E-opt: 0.2 (0.224), width: 16 Scan time: 10.760 The best scores are: opt bits E(85289) NP_055078 (OMIM: 607472) ATP-dependent zinc metall ( 716) 4629 933.7 0 NP_647473 (OMIM: 607472) ATP-dependent zinc metall ( 773) 4285 865.2 0 NP_001240795 (OMIM: 607472) ATP-dependent zinc met ( 683) 3669 742.3 1.4e-213 XP_011517602 (OMIM: 607472) PREDICTED: ATP-depende ( 740) 3669 742.3 1.6e-213 NP_006787 (OMIM: 604581,610246,614487) AFG3-like p ( 797) 1143 238.7 6.9e-62 NP_003110 (OMIM: 602783,607259) paraplegin isoform ( 795) 1015 213.1 3.3e-54 XP_006721327 (OMIM: 602783,607259) PREDICTED: para ( 809) 1015 213.2 3.4e-54 XP_011523903 (OMIM: 604581,610246,614487) PREDICTE ( 730) 928 195.8 5.2e-49 XP_016879087 (OMIM: 602783,607259) PREDICTED: para ( 561) 755 161.2 1e-38 XP_016879086 (OMIM: 602783,607259) PREDICTED: para ( 618) 755 161.3 1.1e-38 NP_001186092 (OMIM: 601681) 26S protease regulator ( 398) 619 134.0 1.1e-30 NP_002796 (OMIM: 601681) 26S protease regulatory s ( 406) 619 134.0 1.1e-30 NP_002794 (OMIM: 154365) 26S protease regulatory s ( 433) 588 127.9 8.5e-29 NP_009057 (OMIM: 167320,601023,613954,616687) tran ( 806) 584 127.2 2.5e-28 XP_016876961 (OMIM: 602708) PREDICTED: 26S proteas ( 288) 564 123.0 1.6e-27 NP_002797 (OMIM: 602708) 26S protease regulatory s ( 403) 564 123.1 2.2e-27 NP_001317141 (OMIM: 602706) 26S protease regulator ( 367) 551 120.5 1.2e-26 XP_016876959 (OMIM: 602706) PREDICTED: 26S proteas ( 367) 551 120.5 1.2e-26 NP_002793 (OMIM: 602706) 26S protease regulatory s ( 440) 551 120.5 1.4e-26 NP_002795 (OMIM: 186852) 26S protease regulatory s ( 439) 543 118.9 4.3e-26 XP_016863318 (OMIM: 613940,616577) PREDICTED: sper ( 765) 538 118.0 1.4e-25 XP_011529980 (OMIM: 613940,616577) PREDICTED: sper ( 916) 538 118.1 1.6e-25 XP_016863314 (OMIM: 613940,616577) PREDICTED: sper ( 917) 538 118.1 1.6e-25 XP_016873515 (OMIM: 186852) PREDICTED: 26S proteas ( 461) 533 116.9 1.8e-25 XP_016856875 (OMIM: 602426) PREDICTED: nuclear val ( 738) 528 116.0 5.3e-25 NP_996671 (OMIM: 602426) nuclear valosin-containin ( 750) 528 116.0 5.4e-25 NP_001230076 (OMIM: 602426) nuclear valosin-contai ( 765) 528 116.0 5.5e-25 XP_016856872 (OMIM: 602426) PREDICTED: nuclear val ( 812) 528 116.0 5.8e-25 NP_002524 (OMIM: 602426) nuclear valosin-containin ( 856) 528 116.1 6.1e-25 NP_694546 (OMIM: 602707) 26S protease regulatory s ( 387) 523 114.9 6.1e-25 XP_016856868 (OMIM: 602426) PREDICTED: nuclear val ( 890) 528 116.1 6.3e-25 NP_006494 (OMIM: 602707) 26S protease regulatory s ( 418) 523 114.9 6.5e-25 XP_016863317 (OMIM: 613940,616577) PREDICTED: sper ( 819) 526 115.6 7.7e-25 NP_001332785 (OMIM: 613940,616577) spermatogenesis ( 892) 526 115.7 8.3e-25 NP_660208 (OMIM: 613940,616577) spermatogenesis-as ( 893) 526 115.7 8.3e-25 NP_955399 (OMIM: 602783,607259) paraplegin isoform ( 489) 522 114.7 8.6e-25 XP_016879088 (OMIM: 602783,607259) PREDICTED: para ( 489) 522 114.7 8.6e-25 XP_016863315 (OMIM: 613940,616577) PREDICTED: sper ( 859) 522 114.9 1.4e-24 XP_005256378 (OMIM: 602783,607259) PREDICTED: para ( 463) 516 113.5 1.9e-24 NP_001230075 (OMIM: 602426) nuclear valosin-contai ( 667) 517 113.8 2.2e-24 XP_011542501 (OMIM: 602426) PREDICTED: nuclear val ( 765) 517 113.8 2.5e-24 XP_011542502 (OMIM: 602426) PREDICTED: nuclear val ( 765) 517 113.8 2.5e-24 XP_011542500 (OMIM: 602426) PREDICTED: nuclear val ( 777) 517 113.8 2.5e-24 XP_016856871 (OMIM: 602426) PREDICTED: nuclear val ( 839) 517 113.9 2.7e-24 XP_016856870 (OMIM: 602426) PREDICTED: nuclear val ( 839) 517 113.9 2.7e-24 XP_011542498 (OMIM: 602426) PREDICTED: nuclear val ( 883) 517 113.9 2.8e-24 XP_016856869 (OMIM: 602426) PREDICTED: nuclear val ( 889) 517 113.9 2.9e-24 XP_016856867 (OMIM: 602426) PREDICTED: nuclear val ( 917) 517 113.9 2.9e-24 XP_005266861 (OMIM: 606696) PREDICTED: katanin p60 ( 491) 508 112.0 6e-24 NP_008975 (OMIM: 606696) katanin p60 ATPase-contai ( 491) 508 112.0 6e-24 >>NP_055078 (OMIM: 607472) ATP-dependent zinc metallopro (716 aa) initn: 4629 init1: 4629 opt: 4629 Z-score: 4989.4 bits: 933.7 E(85289): 0 Smith-Waterman score: 4629; 100.0% identity (100.0% similar) in 716 aa overlap (1-716:1-716) 10 20 30 40 50 60 pF1KB3 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSEPSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSEPSLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LRDLGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LRDLGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SSCLYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SSCLYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GFLLRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GFLLRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 FVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 SRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 IIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 TVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 YHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 RVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAI 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 EQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR 670 680 690 700 710 >>NP_647473 (OMIM: 607472) ATP-dependent zinc metallopro (773 aa) initn: 4282 init1: 4282 opt: 4285 Z-score: 4618.2 bits: 865.2 E(85289): 0 Smith-Waterman score: 4346; 92.4% identity (92.4% similar) in 748 aa overlap (26-716:26-773) 10 20 30 40 50 pF1KB3 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSE---- ::::::::::::::::::::::::::::::: NP_647 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSECMFS 10 20 30 40 50 60 60 pF1KB3 -----------------------------------------------------PSLNLRD ::::::: NP_647 DFLTKLNIVSIGKGKIFEGYRSMFMEPAKRMKKSLDTTDNWHIRPEPFSLSIPPSLNLRD 70 80 90 100 110 120 70 80 90 100 110 120 pF1KB3 LGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 LGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSC 130 140 150 160 170 180 130 140 150 160 170 180 pF1KB3 LYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 LYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFL 190 200 210 220 230 240 190 200 210 220 230 240 pF1KB3 LRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 LRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVL 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB3 LLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 LLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKN 310 320 330 340 350 360 310 320 330 340 350 360 pF1KB3 PQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 PQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRI 370 380 390 400 410 420 370 380 390 400 410 420 pF1KB3 RNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 RNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIG 430 440 450 460 470 480 430 440 450 460 470 480 pF1KB3 ATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 ATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVG 490 500 510 520 530 540 490 500 510 520 530 540 pF1KB3 FSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 FSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHE 550 560 570 580 590 600 550 560 570 580 590 600 pF1KB3 SGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 SGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KB3 EELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 EELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQE 670 680 690 700 710 720 670 680 690 700 710 pF1KB3 IRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 IRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR 730 740 750 760 770 >>NP_001240795 (OMIM: 607472) ATP-dependent zinc metallo (683 aa) initn: 4379 init1: 3668 opt: 3669 Z-score: 3955.2 bits: 742.3 E(85289): 1.4e-213 Smith-Waterman score: 4317; 95.4% identity (95.4% similar) in 716 aa overlap (1-716:1-683) 10 20 30 40 50 60 pF1KB3 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSEPSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSEPSLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LRDLGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLR :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRDLGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKY---------- 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 SSCLYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVK ::::::::::::::::::::::::::::::::::::: NP_001 -----------------------VFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVK 120 130 140 190 200 210 220 230 240 pF1KB3 GFLLRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFLLRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLIL 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB3 FVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEF 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB3 LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGA 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB3 SRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVI 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB3 IIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARG 390 400 410 420 430 440 490 500 510 520 530 540 pF1KB3 TVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITA 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB3 YHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGG 510 520 530 540 550 560 610 620 630 640 650 660 pF1KB3 RVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAI 570 580 590 600 610 620 670 680 690 700 710 pF1KB3 EQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR 630 640 650 660 670 680 >>XP_011517602 (OMIM: 607472) PREDICTED: ATP-dependent z (740 aa) initn: 4032 init1: 3668 opt: 3669 Z-score: 3954.6 bits: 742.3 E(85289): 1.6e-213 Smith-Waterman score: 4193; 88.4% identity (88.4% similar) in 773 aa overlap (1-716:1-740) 10 20 30 40 50 pF1KB3 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSE---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSECMFS 10 20 30 40 50 60 60 pF1KB3 -----------------------------------------------------PSLNLRD ::::::: XP_011 DFLTKLNIVSIGKGKIFEGYRSMFMEPAKRMKKSLDTTDNWHIRPEPFSLSIPPSLNLRD 70 80 90 100 110 120 70 80 90 100 110 120 pF1KB3 LGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSC ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKY------------- 130 140 150 160 130 140 150 160 170 180 pF1KB3 LYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFL :::::::::::::::::::::::::::::::::::::::: XP_011 --------------------VFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFL 170 180 190 200 190 200 210 220 230 240 pF1KB3 LRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVL 210 220 230 240 250 260 250 260 270 280 290 300 pF1KB3 LLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKN 270 280 290 300 310 320 310 320 330 340 350 360 pF1KB3 PQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRI 330 340 350 360 370 380 370 380 390 400 410 420 pF1KB3 RNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIG 390 400 410 420 430 440 430 440 450 460 470 480 pF1KB3 ATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVG 450 460 470 480 490 500 490 500 510 520 530 540 pF1KB3 FSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHE 510 520 530 540 550 560 550 560 570 580 590 600 pF1KB3 SGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVA 570 580 590 600 610 620 610 620 630 640 650 660 pF1KB3 EELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQE 630 640 650 660 670 680 670 680 690 700 710 pF1KB3 IRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR 690 700 710 720 730 740 >>NP_006787 (OMIM: 604581,610246,614487) AFG3-like prote (797 aa) initn: 1138 init1: 495 opt: 1143 Z-score: 1232.0 bits: 238.7 E(85289): 6.9e-62 Smith-Waterman score: 1199; 43.7% identity (74.4% similar) in 449 aa overlap (278-712:304-748) 250 260 270 280 290 300 pF1KB3 IYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKF .: :. : : :::: :..: :.:::::... NP_006 GPAGIGRTGRGMGGLFSVGETTAKVLKDEIDVKFKDVAGCEEAKLEIMEFVNFLKNPKQY 280 290 300 310 320 330 310 320 330 340 350 360 pF1KB3 TILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLF ::.:.::: .:.:::::::::::.:.::::.::: .::::: ::::::: .:.:.:: NP_006 QDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLF 340 350 360 370 380 390 370 380 390 400 410 420 pF1KB3 REAKANAPCVIFIDELDSVGGKRIESPMHPYSRQ--TINQLLAEMDGFKPNEGVIIIGAT :. ::::..::::.:.:: :: .. . :.: :.::::.:::::. . .:.:...: NP_006 ALARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGT 400 410 420 430 440 450 430 440 450 460 470 480 pF1KB3 NFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARG----T : :. :: ::.:::::: :. . ::.:::. :.: .: .:.:.... . .:: : NP_006 NRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASLT 460 470 480 490 500 510 490 500 510 520 530 540 pF1KB3 VGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAY :::::.. :. :.::: :: .. ...:..: . .... : :... .. ..: .:: NP_006 PGFSGADVANVCNEAALIAARHLSDSINQKHFEQAIERVIGGLEKKTQVLQPEEKKTVAY 520 530 540 550 560 570 550 560 570 580 590 600 pF1KB3 HESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGR ::.:::. ..: . : :. :..:.::: ::... ::. ... :. ::: .: ...::: NP_006 HEAGHAVAGWYLEHADPLLKVSIIPRGKGLGYAQYLPK-EQYLYTKEQLLDRMCMTLGGR 580 590 600 610 620 630 610 620 630 640 650 pF1KB3 VAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYS--DTGKL------S :.::..:: .:::::..:. ..:. : ....:::.::.: .... : . : NP_006 VSEEIFFG--RITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDMVLEKPYS 640 650 660 670 680 690 660 670 680 690 700 710 pF1KB3 PETQSAIEQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKL : :..:.:::. :.:.:. .: . . ...: :: :.:: ... . : : . NP_006 EATARLIDDEVRILINDAYKRTVALLTEKKADVEKVALLLLEKEVLDKNDM-VELLGPRP 700 710 720 730 740 pF1KB3 EVR NP_006 FAEKSTYEEFVEGTGSLDEDTSLPEGLKDWNKEREKEKEEPPGEKVAN 750 760 770 780 790 >>NP_003110 (OMIM: 602783,607259) paraplegin isoform 1 p (795 aa) initn: 913 init1: 470 opt: 1015 Z-score: 1094.1 bits: 213.1 E(85289): 3.3e-54 Smith-Waterman score: 1076; 38.6% identity (73.5% similar) in 456 aa overlap (269-708:296-747) 240 250 260 270 280 290 pF1KB3 ILFVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVV . :: . :.:.:. : :..::: :..: : NP_003 AILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDGKMGKGVSFKDVAGMHEAKLEVREFV 270 280 290 300 310 320 300 310 320 330 340 350 pF1KB3 EFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGV ..::.:..: ::.:.::: ::.:::: ::::::.::: ::.::: .: :: :.. :. NP_003 DYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGL 330 340 350 360 370 380 360 370 380 390 400 410 pF1KB3 GASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYS----RQTINQLLAEMDGFK ::.:.:.::.::.: :::...:::.:.:: :: . : .: .::.::::.::::. NP_003 GAARVRSLFKEARARAPCIVYIDEIDAVGKKR-STTMSGFSNTEEEQTLNQLLVEMDGMG 390 400 410 420 430 440 420 430 440 450 460 470 pF1KB3 PNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVD- .. ::....:: . ::.::.::::.: .: . : .. : ::.. .:...:. :: NP_003 TTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHLKSLKLTQSSTF 450 460 470 480 490 500 480 490 500 510 520 530 pF1KB3 -PEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEID . .:. : :::::.. :. :.:::.:: .:. : ..:.. ...: : ..: .. NP_003 YSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAGTAKKSKILS 510 520 530 540 550 560 540 550 560 570 580 590 pF1KB3 NKNKTITAYHESGHAIIAYYTKDAMPINKATIMPR-GPTLGHVSLLPENDRWNETRAQLL .... ..:.::::::..... . . . :..: :: . .:: ...::. :. :. ::. NP_003 KEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRTNAALGFAQMLPR-DQHLFTKEQLF 570 580 590 600 610 620 600 610 620 630 640 pF1KB3 AQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDT-- .: ...:::..: : : ...:.::..:. ..:.:: :: .:::. .: ... .. NP_003 ERMCMALGGRASEALSF--NEVTSGAQDDLRKVTRIAYSMVKQFGMAPGIGPISFPEAQE 630 640 650 660 670 680 650 660 670 680 690 700 pF1KB3 -----GK--LSPETQSAIEQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAK :. .: :. ...: :.:. .:......:. . . . ::.::: :... . NP_003 GLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQDNLDKLQALANALLEKEVINYE 690 700 710 720 730 740 710 pF1KB3 EIQIVLEGKKLEVR .:. .. NP_003 DIEALIGPPPHGPKKMIAPQRWIDAQREKQDLGEEETEETQQPPLGGEEPTWPK 750 760 770 780 790 >>XP_006721327 (OMIM: 602783,607259) PREDICTED: parapleg (809 aa) initn: 913 init1: 470 opt: 1015 Z-score: 1094.0 bits: 213.2 E(85289): 3.4e-54 Smith-Waterman score: 1038; 39.5% identity (73.8% similar) in 428 aa overlap (269-680:296-719) 240 250 260 270 280 290 pF1KB3 ILFVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVV . :: . :.:.:. : :..::: :..: : XP_006 AILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDGKMGKGVSFKDVAGMHEAKLEVREFV 270 280 290 300 310 320 300 310 320 330 340 350 pF1KB3 EFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGV ..::.:..: ::.:.::: ::.:::: ::::::.::: ::.::: .: :: :.. :. XP_006 DYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGL 330 340 350 360 370 380 360 370 380 390 400 410 pF1KB3 GASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYS----RQTINQLLAEMDGFK ::.:.:.::.::.: :::...:::.:.:: :: . : .: .::.::::.::::. XP_006 GAARVRSLFKEARARAPCIVYIDEIDAVGKKR-STTMSGFSNTEEEQTLNQLLVEMDGMG 390 400 410 420 430 440 420 430 440 450 460 470 pF1KB3 PNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVD- .. ::....:: . ::.::.::::.: .: . : .. : ::.. .:...:. :: XP_006 TTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHLKSLKLTQSSTF 450 460 470 480 490 500 480 490 500 510 520 530 pF1KB3 -PEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEID . .:. : :::::.. :. :.:::.:: .:. : ..:.. ...: : ..: .. XP_006 YSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAGTAKKSKILS 510 520 530 540 550 560 540 550 560 570 580 590 pF1KB3 NKNKTITAYHESGHAIIAYYTKDAMPINKATIMPR-GPTLGHVSLLPENDRWNETRAQLL .... ..:.::::::..... . . . :..: :: . .:: ...::. :. :. ::. XP_006 KEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRTNAALGFAQMLPR-DQHLFTKEQLF 570 580 590 600 610 620 600 610 620 630 640 pF1KB3 AQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDT-- .: ...:::..: : : ...:.::..:. ..:.:: :: .:::. .: ... .. XP_006 ERMCMALGGRASEALSF--NEVTSGAQDDLRKVTRIAYSMVKQFGMAPGIGPISFPEAQE 630 640 650 660 670 680 650 660 670 680 690 700 pF1KB3 -----GK--LSPETQSAIEQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAK :. .: :. ...: :.:. .:......:. XP_006 GLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQDNLDKLQARALCVTWGSCLGPL 690 700 710 720 730 740 710 pF1KB3 EIQIVLEGKKLEVR XP_006 DCRPQPAAAASGQVWAVPSPAEAGLPVDPCSSRLTKQLCRARAHHSGSHNGSKAAAGKRP 750 760 770 780 790 800 >>XP_011523903 (OMIM: 604581,610246,614487) PREDICTED: A (730 aa) initn: 955 init1: 496 opt: 928 Z-score: 1000.9 bits: 195.8 E(85289): 5.2e-49 Smith-Waterman score: 928; 47.1% identity (76.3% similar) in 308 aa overlap (278-578:304-611) 250 260 270 280 290 300 pF1KB3 IYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKF .: :. : : :::: :..: :.:::::... XP_011 GPAGIGRTGRGMGGLFSVGETTAKVLKDEIDVKFKDVAGCEEAKLEIMEFVNFLKNPKQY 280 290 300 310 320 330 310 320 330 340 350 360 pF1KB3 TILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLF ::.:.::: .:.:::::::::::.:.::::.::: .::::: ::::::: .:.:.:: XP_011 QDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLF 340 350 360 370 380 390 370 380 390 400 410 420 pF1KB3 REAKANAPCVIFIDELDSVGGKRIESPMHPYSRQ--TINQLLAEMDGFKPNEGVIIIGAT :. ::::..::::.:.:: :: .. . :.: :.::::.:::::. . .:.:...: XP_011 ALARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGT 400 410 420 430 440 450 430 440 450 460 470 480 pF1KB3 NFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARG----T : :. :: ::.:::::: :. . ::.:::. :.: .: .:.:.... . .:: : XP_011 NRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASLT 460 470 480 490 500 510 490 500 510 520 530 540 pF1KB3 VGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAY :::::.. :. :.::: :: .. ...:..: . .... : :... .. ..: .:: XP_011 PGFSGADVANVCNEAALIAARHLSDSINQKHFEQAIERVIGGLEKKTQVLQPEEKKTVAY 520 530 540 550 560 570 550 560 570 580 590 600 pF1KB3 HESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSL-LPENDRWNETRAQLLAQMDVSMGG ::.:::. ..: . : :. : . . . .:..:. :: XP_011 HEAGHAVAGWYLEHADPLLKIVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARLIDDE 580 590 600 610 620 630 610 620 630 640 650 660 pF1KB3 RVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAI XP_011 VRILINDAYKRTVALLTEKKADVEKVALLLLEKEVLDKNDMVELLGPRPFAEKSTYEEFV 640 650 660 670 680 690 >>XP_016879087 (OMIM: 602783,607259) PREDICTED: parapleg (561 aa) initn: 742 init1: 470 opt: 755 Z-score: 816.3 bits: 161.2 E(85289): 1e-38 Smith-Waterman score: 755; 46.3% identity (76.1% similar) in 259 aa overlap (269-521:296-553) 240 250 260 270 280 290 pF1KB3 ILFVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVV . :: . :.:.:. : :..::: :..: : XP_016 AILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDGKMGKGVSFKDVAGMHEAKLEVREFV 270 280 290 300 310 320 300 310 320 330 340 350 pF1KB3 EFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGV ..::.:..: ::.:.::: ::.:::: ::::::.::: ::.::: .: :: :.. :. XP_016 DYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGL 330 340 350 360 370 380 360 370 380 390 400 410 pF1KB3 GASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYS----RQTINQLLAEMDGFK ::.:.:.::.::.: :::...:::.:.:: :: . : .: .::.::::.::::. XP_016 GAARVRSLFKEARARAPCIVYIDEIDAVGKKR-STTMSGFSNTEEEQTLNQLLVEMDGMG 390 400 410 420 430 440 420 430 440 450 460 470 pF1KB3 PNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVD- .. ::....:: . ::.::.::::.: .: . : .. : ::.. .:...:. :: XP_016 TTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHLKSLKLTQSSTF 450 460 470 480 490 500 480 490 500 510 520 530 pF1KB3 -PEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEID . .:. : :::::.. :. :.:::.:: .:. : ..:.. ...: XP_016 YSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAVWGLRRL 510 520 530 540 550 560 540 550 560 570 580 590 pF1KB3 NKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLA >>XP_016879086 (OMIM: 602783,607259) PREDICTED: parapleg (618 aa) initn: 742 init1: 470 opt: 755 Z-score: 815.6 bits: 161.3 E(85289): 1.1e-38 Smith-Waterman score: 755; 46.3% identity (76.1% similar) in 259 aa overlap (269-521:296-553) 240 250 260 270 280 290 pF1KB3 ILFVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVV . :: . :.:.:. : :..::: :..: : XP_016 AILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDGKMGKGVSFKDVAGMHEAKLEVREFV 270 280 290 300 310 320 300 310 320 330 340 350 pF1KB3 EFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGV ..::.:..: ::.:.::: ::.:::: ::::::.::: ::.::: .: :: :.. :. XP_016 DYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGL 330 340 350 360 370 380 360 370 380 390 400 410 pF1KB3 GASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYS----RQTINQLLAEMDGFK ::.:.:.::.::.: :::...:::.:.:: :: . : .: .::.::::.::::. XP_016 GAARVRSLFKEARARAPCIVYIDEIDAVGKKR-STTMSGFSNTEEEQTLNQLLVEMDGMG 390 400 410 420 430 440 420 430 440 450 460 470 pF1KB3 PNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVD- .. ::....:: . ::.::.::::.: .: . : .. : ::.. .:...:. :: XP_016 TTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHLKSLKLTQSSTF 450 460 470 480 490 500 480 490 500 510 520 530 pF1KB3 -PEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEID . .:. : :::::.. :. :.:::.:: .:. : ..:.. ...: XP_016 YSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAAWVWWAQPSP 510 520 530 540 550 560 540 550 560 570 580 590 pF1KB3 NKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLA XP_016 SLMGAELQPLTVGRRAAAARGCGGTAVLSAQQGLCGEVWICSTTSGETHGPDRQ 570 580 590 600 610 716 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:36:48 2016 done: Thu Nov 3 20:36:50 2016 Total Scan time: 10.760 Total Display time: 0.160 Function used was FASTA [36.3.4 Apr, 2011]