FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3093, 745 aa 1>>>pF1KB3093 745 - 745 aa - 745 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5519+/-0.00117; mu= 12.8948+/- 0.069 mean_var=72.3883+/-14.910, 0's: 0 Z-trim(102.1): 49 B-trim: 301 in 1/48 Lambda= 0.150744 statistics sampled from 6785 (6820) to 6785 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.572), E-opt: 0.2 (0.209), width: 16 Scan time: 3.760 The best scores are: opt bits E(32554) CCDS11407.1 JUP gene_id:3728|Hs108|chr17 ( 745) 4830 1060.4 0 CCDS2694.1 CTNNB1 gene_id:1499|Hs108|chr3 ( 781) 3164 698.0 1.4e-200 >>CCDS11407.1 JUP gene_id:3728|Hs108|chr17 (745 aa) initn: 4830 init1: 4830 opt: 4830 Z-score: 5673.0 bits: 1060.4 E(32554): 0 Smith-Waterman score: 4830; 99.9% identity (100.0% similar) in 745 aa overlap (1-745:1-745) 10 20 30 40 50 60 pF1KB3 MEVMNLMEQPIKVTEWQQTYTYDSGIHSGANTCVPSVSSKGIMEEDEACGRQYTLKKTTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MEVMNLMEQPIKVTEWQQTYTYDSGIHSGANTCVPSVSSKGIMEEDEACGRQYTLKKTTT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 YTQGVPPSQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQATNLQRLAEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YTQGVPPSQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQATNLQRLAEPS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 QLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 QLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 SVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 ESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 NNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 GIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 HVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 HVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 QRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 QRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 RKRVSVELTNSLFKHDPAAWEAAQSMIPINEPYGDDLDATYRPMYSSDVPLDPLEMHMDM ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: CCDS11 RKRVSVELTNSLFKHDPAAWEAAQSMIPINEPYGDDMDATYRPMYSSDVPLDPLEMHMDM 670 680 690 700 710 720 730 740 pF1KB3 DGDYPIDTYSDGLRPPYPTADHMLA ::::::::::::::::::::::::: CCDS11 DGDYPIDTYSDGLRPPYPTADHMLA 730 740 >>CCDS2694.1 CTNNB1 gene_id:1499|Hs108|chr3 (781 aa) initn: 3118 init1: 2428 opt: 3164 Z-score: 3714.5 bits: 698.0 E(32554): 1.4e-200 Smith-Waterman score: 3187; 68.5% identity (85.1% similar) in 752 aa overlap (1-731:8-755) 10 20 30 40 50 pF1KB3 MEVMNLMEQPIK--VTEWQQTYTYDSGIHSGANTCVPSVSSKGIMEEDEACGR ::. :: : :..::: ::::::::.: .::.:.:: ::... CCDS26 MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS 10 20 30 40 50 60 60 70 80 90 100 pF1KB3 QYTLKKTTTYTQGVPPSQ-GDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEG-Q : . ..:. : .:.. :.. : ::.::: :: : . : .. .:: .. . CCDS26 QVLYEWEQGFSQSFTQEQVADIDGQYAMT-RAQRVRAAMFPETLDEGMQIP-STQFDAAH 70 80 90 100 110 110 120 130 140 150 160 pF1KB3 ATNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQL ::.::::::::.:: :.:.::::::::::::::.::::::::::: :::.:::..:.:: CCDS26 PTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQL 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB3 SKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIP :::::::.:.: :::.:.:.:::::::.:..:::::.. ::::::::::::::::::::: CCDS26 SKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIP 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB3 ALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITT :::.::.:::.:::::::::::::::.::::::::::: :::::: ::::.: ::::::: CCDS26 ALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITT 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB3 DCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIV ::::.::::::::::::::.:::::::.:::.:.:::::::::::::::::: ::::::: CCDS26 DCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIV 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB3 EAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLT ::::::::: :::. : :::::::::::::::.::::::.:..: ::. :. ::.::.: CCDS26 EAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVT 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB3 CATGTLSNLTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEA ::.: :::::::: ::: .: : .:.:::....:::::..::::::.:::::::::: :: CCDS26 CAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEA 420 430 440 450 460 470 470 480 490 500 510 520 pF1KB3 EMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQ :::::.:::.::.:..::::. :..:::.:::.::::::::::::::::.: ..:::::: CCDS26 EMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQ 480 490 500 510 520 530 530 540 550 560 570 580 pF1KB3 LLVKAHQDAQRHVA-AGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPL :::.::::.::... .:::: ...::::::::::::::::::::: ::. : :::::: CCDS26 LLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPL 540 550 560 570 580 590 590 600 610 620 630 640 pF1KB3 FVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAV ::::::: .:::::::::::::::::::::.::.::::.::: :::::::::.::::::: CCDS26 FVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAV 600 610 620 630 640 650 650 660 670 680 690 700 pF1KB3 LFRISEDKNPDYRKRVSVELTNSLFKHDPAAW-EAAQSMIPIN---EPYG--DDLDATYR :::.:::: ::.::.:::::.:::. .: :: :.:. . :. :: : .: : .:: CCDS26 LFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQD-DPSYR 660 670 680 690 700 710 710 720 730 740 pF1KB3 PMYSSD-----VPLDPLEMHMDMDG-----DYPIDTYSDGLRPPYPTADHMLA ..:. . .::. :. .: : :::.: : CCDS26 SFHSGGYGQDALGMDPM-MEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAW 720 730 740 750 760 770 CCDS26 FDTDL 780 745 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:21:46 2016 done: Thu Nov 3 12:21:47 2016 Total Scan time: 3.760 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]