FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3095, 327 aa 1>>>pF1KB3095 327 - 327 aa - 327 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8530+/-0.000322; mu= 17.8787+/- 0.020 mean_var=59.5580+/-11.913, 0's: 0 Z-trim(115.5): 51 B-trim: 48 in 1/49 Lambda= 0.166190 statistics sampled from 26017 (26072) to 26017 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.306), width: 16 Scan time: 7.460 The best scores are: opt bits E(85289) NP_996759 (OMIM: 600590) serine/threonine-protein ( 327) 2276 553.9 1.6e-157 NP_002700 (OMIM: 600590) serine/threonine-protein ( 327) 2276 553.9 1.6e-157 NP_002699 (OMIM: 176875) serine/threonine-protein ( 330) 2034 495.9 4.8e-140 NP_001231903 (OMIM: 176914) serine/threonine-prote ( 337) 1990 485.4 7.3e-137 NP_002701 (OMIM: 176914) serine/threonine-protein ( 323) 1983 483.7 2.3e-136 XP_011536807 (OMIM: 176914) PREDICTED: serine/thre ( 330) 1983 483.7 2.3e-136 XP_011536806 (OMIM: 176914) PREDICTED: serine/thre ( 362) 1983 483.7 2.5e-136 NP_001008709 (OMIM: 176875) serine/threonine-prote ( 341) 1970 480.6 2.1e-135 NP_996756 (OMIM: 176875) serine/threonine-protein ( 286) 1719 420.3 2.3e-117 NP_001009552 (OMIM: 176916) serine/threonine-prote ( 309) 978 242.7 7.5e-64 NP_001290432 (OMIM: 602035) serine/threonine-prote ( 307) 977 242.5 8.8e-64 NP_002711 (OMIM: 602035) serine/threonine-protein ( 307) 977 242.5 8.8e-64 NP_002706 (OMIM: 176915) serine/threonine-protein ( 309) 967 240.1 4.7e-63 NP_002712 (OMIM: 612725) serine/threonine-protein ( 305) 864 215.4 1.3e-55 XP_011517149 (OMIM: 612725) PREDICTED: serine/thre ( 293) 854 213.0 6.4e-55 NP_001116827 (OMIM: 612725) serine/threonine-prote ( 342) 854 213.0 7.3e-55 XP_016878893 (OMIM: 602035) PREDICTED: serine/thre ( 228) 760 190.3 3.2e-48 NP_001290436 (OMIM: 602035) serine/threonine-prote ( 228) 760 190.3 3.2e-48 NP_001290435 (OMIM: 602035) serine/threonine-prote ( 228) 760 190.3 3.2e-48 XP_016878892 (OMIM: 602035) PREDICTED: serine/thre ( 228) 760 190.3 3.2e-48 NP_006238 (OMIM: 600658) serine/threonine-protein ( 499) 703 176.9 7.8e-44 XP_016882424 (OMIM: 600658) PREDICTED: serine/thre ( 551) 703 176.9 8.5e-44 NP_001116841 (OMIM: 612725) serine/threonine-prote ( 283) 697 175.3 1.3e-43 NP_001191213 (OMIM: 600658) serine/threonine-prote ( 477) 695 175.0 2.8e-43 NP_001290433 (OMIM: 602035) serine/threonine-prote ( 273) 681 171.5 1.9e-42 XP_006721124 (OMIM: 602035) PREDICTED: serine/thre ( 273) 681 171.5 1.9e-42 NP_001124164 (OMIM: 114105) serine/threonine-prote ( 469) 682 171.8 2.4e-42 XP_016863854 (OMIM: 114105) PREDICTED: serine/thre ( 509) 682 171.9 2.6e-42 NP_001124163 (OMIM: 114105) serine/threonine-prote ( 511) 682 171.9 2.6e-42 NP_000935 (OMIM: 114105) serine/threonine-protein ( 521) 682 171.9 2.7e-42 XP_016869100 (OMIM: 114107) PREDICTED: serine/thre ( 418) 673 169.7 9.9e-42 NP_001230904 (OMIM: 114107) serine/threonine-prote ( 502) 673 169.7 1.1e-41 NP_005596 (OMIM: 114107) serine/threonine-protein ( 512) 673 169.7 1.2e-41 NP_001230903 (OMIM: 114107) serine/threonine-prote ( 521) 673 169.7 1.2e-41 XP_016871868 (OMIM: 114106) PREDICTED: serine/thre ( 426) 670 168.9 1.7e-41 XP_005270001 (OMIM: 114106) PREDICTED: serine/thre ( 514) 670 169.0 1.9e-41 NP_001135826 (OMIM: 114106) serine/threonine-prote ( 515) 670 169.0 1.9e-41 NP_066955 (OMIM: 114106) serine/threonine-protein ( 524) 670 169.0 2e-41 NP_001135825 (OMIM: 114106) serine/threonine-prote ( 525) 670 169.0 2e-41 XP_016869099 (OMIM: 114107) PREDICTED: serine/thre ( 439) 668 168.5 2.4e-41 NP_001276898 (OMIM: 114106) serine/threonine-prote ( 410) 666 168.0 3.1e-41 NP_001276897 (OMIM: 114106) serine/threonine-prote ( 514) 430 111.4 4e-24 XP_011530341 (OMIM: 602256) PREDICTED: serine/thre ( 753) 385 100.8 9.7e-21 NP_006230 (OMIM: 602256) serine/threonine-protein ( 753) 385 100.8 9.7e-21 NP_689412 (OMIM: 300109) serine/threonine-protein ( 591) 335 88.7 3.3e-17 XP_016885101 (OMIM: 300109) PREDICTED: serine/thre ( 563) 195 55.1 4e-07 NP_689410 (OMIM: 300109) serine/threonine-protein ( 625) 195 55.2 4.3e-07 NP_006231 (OMIM: 300109) serine/threonine-protein ( 653) 195 55.2 4.5e-07 XP_005274610 (OMIM: 300109) PREDICTED: serine/thre ( 653) 195 55.2 4.5e-07 >>NP_996759 (OMIM: 600590) serine/threonine-protein phos (327 aa) initn: 2276 init1: 2276 opt: 2276 Z-score: 2948.9 bits: 553.9 E(85289): 1.6e-157 Smith-Waterman score: 2276; 100.0% identity (100.0% similar) in 327 aa overlap (1-327:1-327) 10 20 30 40 50 60 pF1KB3 MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK 250 260 270 280 290 300 310 320 pF1KB3 KAKYQYGGLNSGRPVTPPRTANPPKKR ::::::::::::::::::::::::::: NP_996 KAKYQYGGLNSGRPVTPPRTANPPKKR 310 320 >>NP_002700 (OMIM: 600590) serine/threonine-protein phos (327 aa) initn: 2276 init1: 2276 opt: 2276 Z-score: 2948.9 bits: 553.9 E(85289): 1.6e-157 Smith-Waterman score: 2276; 100.0% identity (100.0% similar) in 327 aa overlap (1-327:1-327) 10 20 30 40 50 60 pF1KB3 MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK 250 260 270 280 290 300 310 320 pF1KB3 KAKYQYGGLNSGRPVTPPRTANPPKKR ::::::::::::::::::::::::::: NP_002 KAKYQYGGLNSGRPVTPPRTANPPKKR 310 320 >>NP_002699 (OMIM: 176875) serine/threonine-protein phos (330 aa) initn: 1995 init1: 1938 opt: 2034 Z-score: 2635.2 bits: 495.9 E(85289): 4.8e-140 Smith-Waterman score: 2034; 88.8% identity (96.1% similar) in 330 aa overlap (1-326:1-330) 10 20 30 40 50 pF1KB3 MADGE-LNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLK :.:.: ::.::.: :::::.: :::: ::.:: :.::::.:::::::::::::::::::: NP_002 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 ICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL ::::::::: ::::::::::::::.::::::::::::::::::::::::::::::::::: NP_002 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 LRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: NP_002 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 QSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHD ::::::::::::::::: :::::::::::::::::::::::::::::::.::.:::..:: NP_002 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSE ::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::.. NP_002 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD 250 260 270 280 290 300 300 310 320 pF1KB3 K-KAKY-QYGGLN-SGRPVTPPRTANPPKKR : :.:: :..::: .:::.::::.. :: NP_002 KNKGKYGQFSGLNPGGRPITPPRNSAKAKK 310 320 330 >>NP_001231903 (OMIM: 176914) serine/threonine-protein p (337 aa) initn: 1986 init1: 1940 opt: 1990 Z-score: 2578.1 bits: 485.4 E(85289): 7.3e-137 Smith-Waterman score: 1990; 87.0% identity (92.7% similar) in 331 aa overlap (1-327:1-325) 10 20 30 40 50 pF1KB3 MAD-GELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLK ::: .::.::.: ::::::: .::: ::. : :.::::.:::::::::::::::::::: NP_001 MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 ICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL ::::::::: ::::::::::::::.::::::::::::::::::::::::::::::::::: NP_001 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 LRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: NP_001 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 QSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHD ::::::::::::::::: ::::::::::::::: :::::::::::::::.::.:::..:: NP_001 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHD 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSE ::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::.: NP_001 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE 250 260 270 280 290 300 300 310 320 pF1KB3 KKAKYQYGGLNSGRPVTPPRTA---NPPKKR :: :. :::::::.: :: .. NP_001 KKKP------NATRPVTPPRVASGLNPSIQKASNYRNNTVLYE 310 320 330 >>NP_002701 (OMIM: 176914) serine/threonine-protein phos (323 aa) initn: 1986 init1: 1940 opt: 1983 Z-score: 2569.3 bits: 483.7 E(85289): 2.3e-136 Smith-Waterman score: 1983; 89.1% identity (94.1% similar) in 320 aa overlap (1-319:1-314) 10 20 30 40 50 pF1KB3 MAD-GELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLK ::: .::.::.: ::::::: .::: ::. : :.::::.:::::::::::::::::::: NP_002 MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 ICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL ::::::::: ::::::::::::::.::::::::::::::::::::::::::::::::::: NP_002 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 LRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: NP_002 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 QSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHD ::::::::::::::::: ::::::::::::::: :::::::::::::::.::.:::..:: NP_002 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHD 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSE ::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::.: NP_002 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE 250 260 270 280 290 300 300 310 320 pF1KB3 KKAKYQYGGLNSGRPVTPPRTANPPKKR :: :. ::::::: NP_002 KKKP------NATRPVTPPRGMITKQAKK 310 320 >>XP_011536807 (OMIM: 176914) PREDICTED: serine/threonin (330 aa) initn: 1986 init1: 1940 opt: 1983 Z-score: 2569.1 bits: 483.7 E(85289): 2.3e-136 Smith-Waterman score: 1983; 89.1% identity (94.1% similar) in 320 aa overlap (1-319:1-314) 10 20 30 40 50 pF1KB3 MAD-GELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLK ::: .::.::.: ::::::: .::: ::. : :.::::.:::::::::::::::::::: XP_011 MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 ICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL ::::::::: ::::::::::::::.::::::::::::::::::::::::::::::::::: XP_011 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 LRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: XP_011 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 QSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHD ::::::::::::::::: ::::::::::::::: :::::::::::::::.::.:::..:: XP_011 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHD 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSE ::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::.: XP_011 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE 250 260 270 280 290 300 300 310 320 pF1KB3 KKAKYQYGGLNSGRPVTPPRTANPPKKR :: :. ::::::: XP_011 KKKP------NATRPVTPPRELPIFFTSLSMGFSAA 310 320 330 >>XP_011536806 (OMIM: 176914) PREDICTED: serine/threonin (362 aa) initn: 1986 init1: 1940 opt: 1983 Z-score: 2568.5 bits: 483.7 E(85289): 2.5e-136 Smith-Waterman score: 1983; 89.1% identity (94.1% similar) in 320 aa overlap (1-319:1-314) 10 20 30 40 50 pF1KB3 MAD-GELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLK ::: .::.::.: ::::::: .::: ::. : :.::::.:::::::::::::::::::: XP_011 MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 ICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL ::::::::: ::::::::::::::.::::::::::::::::::::::::::::::::::: XP_011 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 LRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: XP_011 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 QSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHD ::::::::::::::::: ::::::::::::::: :::::::::::::::.::.:::..:: XP_011 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHD 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSE ::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::.: XP_011 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE 250 260 270 280 290 300 300 310 320 pF1KB3 KKAKYQYGGLNSGRPVTPPRTANPPKKR :: :. ::::::: XP_011 KKKP------NATRPVTPPRATQLAQYQTPCLPERTIPHTSCSGLVNKRTVNWSLYSWTD 310 320 330 340 350 >>NP_001008709 (OMIM: 176875) serine/threonine-protein p (341 aa) initn: 1969 init1: 1871 opt: 1970 Z-score: 2552.1 bits: 480.6 E(85289): 2.1e-135 Smith-Waterman score: 2002; 85.9% identity (93.0% similar) in 341 aa overlap (1-326:1-341) 10 20 30 40 pF1KB3 MADGE-LNVDSLITRLLE-----------VRGCRPGKIVQMTEAEVRGLCIKSREIFLSQ :.:.: ::.::.: :::: :.: :::: ::.:: :.::::.::::::::: NP_001 MSDSEKLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQ 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB3 PILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLA :::::::::::::::::::: ::::::::::::::.:::::::::::::::::::::::: NP_001 PILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLA 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB3 YKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKI ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_001 YKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKI 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB3 FCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA :::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::: NP_001 FCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB3 DVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETL .::.:::..::::::::::::::::::::::::::::::::::::::::::.:::::::: NP_001 EVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETL 250 260 270 280 290 300 290 300 310 320 pF1KB3 MCSFQILKPSEK-KAKY-QYGGLN-SGRPVTPPRTANPPKKR :::::::::..: :.:: :..::: .:::.::::.. :: NP_001 MCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 310 320 330 340 >>NP_996756 (OMIM: 176875) serine/threonine-protein phos (286 aa) initn: 1731 init1: 1633 opt: 1719 Z-score: 2227.9 bits: 420.3 E(85289): 2.3e-117 Smith-Waterman score: 1719; 91.0% identity (97.0% similar) in 268 aa overlap (62-326:19-286) 40 50 60 70 80 90 pF1KB3 AEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGD ::::::: ::::::::::::::.::::::: NP_996 MSDSEKLNLDSIIGRLLEGDIHGQYYDLLRLFEYGGFPPESNYLFLGD 10 20 30 40 100 110 120 130 140 150 pF1KB3 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTF :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: NP_996 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTF 50 60 70 80 90 100 160 170 180 190 200 210 pF1KB3 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKD ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: NP_996 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD 110 120 130 140 150 160 220 230 240 250 260 270 pF1KB3 VQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY :::::::::::::::::.::.:::..:::::::::::::::::::::::::::::::::: NP_996 VQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 170 180 190 200 210 220 280 290 300 310 320 pF1KB3 CGEFDNAGGMMSVDETLMCSFQILKPSEK-KAKY-QYGGLN-SGRPVTPPRTANPPKKR ::::::::.:::::::::::::::::..: :.:: :..::: .:::.::::.. :: NP_996 CGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 230 240 250 260 270 280 >>NP_001009552 (OMIM: 176916) serine/threonine-protein p (309 aa) initn: 627 init1: 627 opt: 978 Z-score: 1267.3 bits: 242.7 E(85289): 7.5e-64 Smith-Waterman score: 978; 48.4% identity (76.5% similar) in 277 aa overlap (28-303:22-297) 10 20 30 40 50 60 pF1KB3 MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI :..: .:: :: :..::. .. . :.. :. . NP_001 MDDKAFTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTV 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL :::.:::. ::..::. :: :..::::.::::::: :.::. ::.: :..::: . .: NP_001 CGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITIL 60 70 80 90 100 110 130 140 150 160 170 pF1KB3 RGNHECASINRIYGFYDECKRRF-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL ::::: .:...::::::: :.. : ..:: ::: :. ::..:.:: .::: ::::::.. NP_001 RGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSI 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 QSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHD .....:: . : .:: : .::::::::: : ::: . ::...::: :. : . . NP_001 DTLDHIRALDRLQEVPHEGPMCDLLWSDPD-DRGGWGISPRGAGYTFGQDISETFNHANG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSE : :. ::::.: .::.. :..::.::::::: . : ...: .:.:: :: . :. NP_001 LTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAP 240 250 260 270 280 290 300 310 320 pF1KB3 KKAKYQYGGLNSGRPVTPPRTANPPKKR .... NP_001 RRGEPHVTRRTPDYFL 300 327 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:09:38 2016 done: Fri Nov 4 02:09:39 2016 Total Scan time: 7.460 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]