FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3100, 856 aa 1>>>pF1KB3100 856 - 856 aa - 856 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.2789+/-0.000488; mu= -16.4963+/- 0.031 mean_var=760.6304+/-158.069, 0's: 0 Z-trim(124.3): 54 B-trim: 0 in 0/61 Lambda= 0.046504 statistics sampled from 45673 (45738) to 45673 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.536), width: 16 Scan time: 15.880 The best scores are: opt bits E(85289) NP_008971 (OMIM: 605800) heterogeneous nuclear rib ( 856) 6054 422.0 5.7e-117 XP_005258516 (OMIM: 605800) PREDICTED: heterogeneo ( 866) 5462 382.3 5.2e-105 NP_001287945 (OMIM: 605800) heterogeneous nuclear ( 767) 5376 376.5 2.6e-103 NP_001308137 (OMIM: 605800) heterogeneous nuclear ( 756) 5371 376.1 3.3e-103 NP_653333 (OMIM: 605800) heterogeneous nuclear rib ( 756) 5371 376.1 3.3e-103 NP_001308140 (OMIM: 605800) heterogeneous nuclear ( 756) 5371 376.1 3.3e-103 XP_011524694 (OMIM: 605800) PREDICTED: heterogeneo ( 792) 5310 372.1 5.7e-102 XP_005258518 (OMIM: 605800) PREDICTED: heterogeneo ( 777) 4784 336.8 2.4e-91 XP_011524697 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 4779 336.4 3e-91 XP_005258520 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 4779 336.4 3e-91 XP_011524695 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 4779 336.4 3e-91 XP_011524696 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 4779 336.4 3e-91 XP_005258522 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 4779 336.4 3e-91 XP_005258521 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 4779 336.4 3e-91 XP_016856604 (OMIM: 602869) PREDICTED: heterogeneo ( 825) 1991 149.4 6.3e-35 XP_016856605 (OMIM: 602869) PREDICTED: heterogeneo ( 825) 1991 149.4 6.3e-35 NP_114032 (OMIM: 602869) heterogeneous nuclear rib ( 825) 1991 149.4 6.3e-35 XP_016856606 (OMIM: 602869) PREDICTED: heterogeneo ( 806) 1966 147.7 2e-34 NP_004492 (OMIM: 602869) heterogeneous nuclear rib ( 806) 1966 147.7 2e-34 >>NP_008971 (OMIM: 605800) heterogeneous nuclear ribonuc (856 aa) initn: 6054 init1: 6054 opt: 6054 Z-score: 2221.0 bits: 422.0 E(85289): 5.7e-117 Smith-Waterman score: 6054; 100.0% identity (100.0% similar) in 856 aa overlap (1-856:1-856) 10 20 30 40 50 60 pF1KB3 MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERELDADDEPGRPGHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERELDADDEPGRPGHI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 NEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 NEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 ESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 RGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 RGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 YLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 YLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 SYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 EALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 CEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 CEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 IQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 IQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 RTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 RTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 AGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 AGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 RSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 RSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 RNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 RNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 PPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 PPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNY 790 800 810 820 830 840 850 pF1KB3 DYGSYSGNTQGGTSTQ :::::::::::::::: NP_008 DYGSYSGNTQGGTSTQ 850 >>XP_005258516 (OMIM: 605800) PREDICTED: heterogeneous n (866 aa) initn: 5578 init1: 5285 opt: 5462 Z-score: 2006.3 bits: 382.3 E(85289): 5.2e-105 Smith-Waterman score: 6024; 98.8% identity (98.8% similar) in 866 aa overlap (1-856:1-866) 10 20 30 40 50 60 pF1KB3 MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERELDADDEPGRPGHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERELDADDEPGRPGHI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 NEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 RGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 YLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 CEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 IQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 RTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 AGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 RSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPA 670 680 690 700 710 720 730 740 750 760 770 pF1KB3 RNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQ----------PSYSQPPYNQGGYSQG :::::::::::::::::::::::::::::::::: :::::::::::::::: XP_005 RNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQSFGFFPSTFQPSYSQPPYNQGGYSQG 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB3 YTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQ 790 800 810 820 830 840 840 850 pF1KB3 GQWPPYYGNYDYGSYSGNTQGGTSTQ :::::::::::::::::::::::::: XP_005 GQWPPYYGNYDYGSYSGNTQGGTSTQ 850 860 >>NP_001287945 (OMIM: 605800) heterogeneous nuclear ribo (767 aa) initn: 5376 init1: 5376 opt: 5376 Z-score: 1975.7 bits: 376.5 E(85289): 2.6e-103 Smith-Waterman score: 5376; 100.0% identity (100.0% similar) in 757 aa overlap (100-856:11-767) 70 80 90 100 110 120 pF1KB3 SELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPL :::::::::::::::::::::::::::::: NP_001 MRSWAFSYLDAMDNITRQNQFYDTQVIKQENESGYERRPL 10 20 30 40 130 140 150 160 170 180 pF1KB3 EMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHRED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHRED 50 60 70 80 90 100 190 200 210 220 230 240 pF1KB3 RRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARAS 110 120 130 140 150 160 250 260 270 280 290 300 pF1KB3 YGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGK 170 180 190 200 210 220 310 320 330 340 350 360 pF1KB3 KSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALY 230 240 250 260 270 280 370 380 390 400 410 420 pF1KB3 PHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGL 290 300 310 320 330 340 430 440 450 460 470 480 pF1KB3 PAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLN 350 360 370 380 390 400 490 500 510 520 530 540 pF1KB3 RLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEE 410 420 430 440 450 460 550 560 570 580 590 600 pF1KB3 GKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRF 470 480 490 500 510 520 610 620 630 640 650 660 pF1KB3 DNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQ 530 540 550 560 570 580 670 680 690 700 710 720 pF1KB3 NRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTY 590 600 610 620 630 640 730 740 750 760 770 780 pF1KB3 NKNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNYGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNYGSY 650 660 670 680 690 700 790 800 810 820 830 840 pF1KB3 GGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNT 710 720 730 740 750 760 850 pF1KB3 QGGTSTQ ::::::: NP_001 QGGTSTQ >>NP_001308137 (OMIM: 605800) heterogeneous nuclear ribo (756 aa) initn: 5371 init1: 5371 opt: 5371 Z-score: 1974.0 bits: 376.1 E(85289): 3.3e-103 Smith-Waterman score: 5371; 100.0% identity (100.0% similar) in 756 aa overlap (101-856:1-756) 80 90 100 110 120 130 pF1KB3 ELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLE :::::::::::::::::::::::::::::: NP_001 MDNITRQNQFYDTQVIKQENESGYERRPLE 10 20 30 140 150 160 170 180 190 pF1KB3 MEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDR 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB3 RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASY 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB3 GVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKK 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB3 STNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYP 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB3 HVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLP 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB3 AAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNR 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB3 LIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEG 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB3 KDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFD 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB3 NRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQN 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB3 RWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYN 580 590 600 610 620 630 740 750 760 770 780 790 pF1KB3 KNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNYGSYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNYGSYG 640 650 660 670 680 690 800 810 820 830 840 850 pF1KB3 GYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNTQ 700 710 720 730 740 750 pF1KB3 GGTSTQ :::::: NP_001 GGTSTQ >>NP_653333 (OMIM: 605800) heterogeneous nuclear ribonuc (756 aa) initn: 5371 init1: 5371 opt: 5371 Z-score: 1974.0 bits: 376.1 E(85289): 3.3e-103 Smith-Waterman score: 5371; 100.0% identity (100.0% similar) in 756 aa overlap (101-856:1-756) 80 90 100 110 120 130 pF1KB3 ELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLE :::::::::::::::::::::::::::::: NP_653 MDNITRQNQFYDTQVIKQENESGYERRPLE 10 20 30 140 150 160 170 180 190 pF1KB3 MEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 MEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDR 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB3 RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASY 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB3 GVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 GVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKK 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB3 STNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 STNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYP 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB3 HVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 HVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLP 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB3 AAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 AAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNR 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB3 LIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 LIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEG 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB3 KDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 KDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFD 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB3 NRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 NRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQN 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB3 RWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 RWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYN 580 590 600 610 620 630 740 750 760 770 780 790 pF1KB3 KNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNYGSYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 KNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNYGSYG 640 650 660 670 680 690 800 810 820 830 840 850 pF1KB3 GYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 GYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNTQ 700 710 720 730 740 750 pF1KB3 GGTSTQ :::::: NP_653 GGTSTQ >>NP_001308140 (OMIM: 605800) heterogeneous nuclear ribo (756 aa) initn: 5371 init1: 5371 opt: 5371 Z-score: 1974.0 bits: 376.1 E(85289): 3.3e-103 Smith-Waterman score: 5371; 100.0% identity (100.0% similar) in 756 aa overlap (101-856:1-756) 80 90 100 110 120 130 pF1KB3 ELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLE :::::::::::::::::::::::::::::: NP_001 MDNITRQNQFYDTQVIKQENESGYERRPLE 10 20 30 140 150 160 170 180 190 pF1KB3 MEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDR 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB3 RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASY 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB3 GVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKK 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB3 STNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYP 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB3 HVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLP 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB3 AAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNR 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB3 LIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEG 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB3 KDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFD 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB3 NRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQN 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB3 RWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYN 580 590 600 610 620 630 740 750 760 770 780 790 pF1KB3 KNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNYGSYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNYGSYG 640 650 660 670 680 690 800 810 820 830 840 850 pF1KB3 GYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNTQ 700 710 720 730 740 750 pF1KB3 GGTSTQ :::::: NP_001 GGTSTQ >>XP_011524694 (OMIM: 605800) PREDICTED: heterogeneous n (792 aa) initn: 5262 init1: 5262 opt: 5310 Z-score: 1951.6 bits: 372.1 E(85289): 5.7e-102 Smith-Waterman score: 5413; 92.5% identity (92.5% similar) in 856 aa overlap (1-856:1-792) 10 20 30 40 50 60 pF1KB3 MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERELDADDEPGRPGHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERELDADDEPGRPGHI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 NEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 RGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 YLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 CEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 IQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 RTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 AGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 RSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 RNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPP :::::::::::::::::::::::::::::::::: XP_011 RNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQ-------------------------- 730 740 750 790 800 810 820 830 840 pF1KB3 PPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNY :::::::::::::::::::::: XP_011 --------------------------------------YAQQWNQYYQNQGQWPPYYGNY 760 770 850 pF1KB3 DYGSYSGNTQGGTSTQ :::::::::::::::: XP_011 DYGSYSGNTQGGTSTQ 780 790 >>XP_005258518 (OMIM: 605800) PREDICTED: heterogeneous n (777 aa) initn: 4900 init1: 4607 opt: 4784 Z-score: 1761.0 bits: 336.8 E(85289): 2.4e-91 Smith-Waterman score: 5346; 98.7% identity (98.7% similar) in 767 aa overlap (100-856:11-777) 70 80 90 100 110 120 pF1KB3 SELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPL :::::::::::::::::::::::::::::: XP_005 MRSWAFSYLDAMDNITRQNQFYDTQVIKQENESGYERRPL 10 20 30 40 130 140 150 160 170 180 pF1KB3 EMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHRED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHRED 50 60 70 80 90 100 190 200 210 220 230 240 pF1KB3 RRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARAS 110 120 130 140 150 160 250 260 270 280 290 300 pF1KB3 YGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGK 170 180 190 200 210 220 310 320 330 340 350 360 pF1KB3 KSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALY 230 240 250 260 270 280 370 380 390 400 410 420 pF1KB3 PHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGL 290 300 310 320 330 340 430 440 450 460 470 480 pF1KB3 PAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLN 350 360 370 380 390 400 490 500 510 520 530 540 pF1KB3 RLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEE 410 420 430 440 450 460 550 560 570 580 590 600 pF1KB3 GKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRF 470 480 490 500 510 520 610 620 630 640 650 660 pF1KB3 DNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQ 530 540 550 560 570 580 670 680 690 700 710 720 pF1KB3 NRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTY 590 600 610 620 630 640 730 740 750 760 770 pF1KB3 NKNSNIPGSSANTSTPTVSSYSPPQ----------PSYSQPPYNQGGYSQGYTAPPPPPP ::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_005 NKNSNIPGSSANTSTPTVSSYSPPQSFGFFPSTFQPSYSQPPYNQGGYSQGYTAPPPPPP 650 660 670 680 690 700 780 790 800 810 820 830 pF1KB3 PPPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGN 710 720 730 740 750 760 840 850 pF1KB3 YDYGSYSGNTQGGTSTQ ::::::::::::::::: XP_005 YDYGSYSGNTQGGTSTQ 770 >>XP_011524697 (OMIM: 605800) PREDICTED: heterogeneous n (766 aa) initn: 4895 init1: 4602 opt: 4779 Z-score: 1759.3 bits: 336.4 E(85289): 3e-91 Smith-Waterman score: 5341; 98.7% identity (98.7% similar) in 766 aa overlap (101-856:1-766) 80 90 100 110 120 130 pF1KB3 ELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLE :::::::::::::::::::::::::::::: XP_011 MDNITRQNQFYDTQVIKQENESGYERRPLE 10 20 30 140 150 160 170 180 190 pF1KB3 MEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDR 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB3 RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASY 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB3 GVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKK 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB3 STNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYP 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB3 HVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLP 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB3 AAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNR 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB3 LIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEG 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB3 KDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFD 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB3 NRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQN 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB3 RWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYN 580 590 600 610 620 630 740 750 760 770 780 pF1KB3 KNSNIPGSSANTSTPTVSSYSPPQ----------PSYSQPPYNQGGYSQGYTAPPPPPPP :::::::::::::::::::::::: :::::::::::::::::::::::::: XP_011 KNSNIPGSSANTSTPTVSSYSPPQSFGFFPSTFQPSYSQPPYNQGGYSQGYTAPPPPPPP 640 650 660 670 680 690 790 800 810 820 830 840 pF1KB3 PPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNY 700 710 720 730 740 750 850 pF1KB3 DYGSYSGNTQGGTSTQ :::::::::::::::: XP_011 DYGSYSGNTQGGTSTQ 760 >>XP_005258520 (OMIM: 605800) PREDICTED: heterogeneous n (766 aa) initn: 4895 init1: 4602 opt: 4779 Z-score: 1759.3 bits: 336.4 E(85289): 3e-91 Smith-Waterman score: 5341; 98.7% identity (98.7% similar) in 766 aa overlap (101-856:1-766) 80 90 100 110 120 130 pF1KB3 ELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLE :::::::::::::::::::::::::::::: XP_005 MDNITRQNQFYDTQVIKQENESGYERRPLE 10 20 30 140 150 160 170 180 190 pF1KB3 MEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDR 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB3 RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASY 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB3 GVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKK 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB3 STNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYP 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB3 HVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLP 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB3 AAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNR 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB3 LIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEG 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB3 KDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFD 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB3 NRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQN 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB3 RWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYN 580 590 600 610 620 630 740 750 760 770 780 pF1KB3 KNSNIPGSSANTSTPTVSSYSPPQ----------PSYSQPPYNQGGYSQGYTAPPPPPPP :::::::::::::::::::::::: :::::::::::::::::::::::::: XP_005 KNSNIPGSSANTSTPTVSSYSPPQSFGFFPSTFQPSYSQPPYNQGGYSQGYTAPPPPPPP 640 650 660 670 680 690 790 800 810 820 830 840 pF1KB3 PPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNY 700 710 720 730 740 750 850 pF1KB3 DYGSYSGNTQGGTSTQ :::::::::::::::: XP_005 DYGSYSGNTQGGTSTQ 760 856 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:23:06 2016 done: Thu Nov 3 12:23:09 2016 Total Scan time: 15.880 Total Display time: 0.310 Function used was FASTA [36.3.4 Apr, 2011]