FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3103, 550 aa 1>>>pF1KB3103 550 - 550 aa - 550 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.3885+/-0.00122; mu= 2.0844+/- 0.073 mean_var=263.5697+/-55.661, 0's: 0 Z-trim(110.5): 85 B-trim: 581 in 2/50 Lambda= 0.079000 statistics sampled from 11613 (11686) to 11613 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.677), E-opt: 0.2 (0.359), width: 16 Scan time: 2.840 The best scores are: opt bits E(32554) CCDS41680.1 CTTN gene_id:2017|Hs108|chr11 ( 550) 3706 435.9 5.9e-122 CCDS8197.1 CTTN gene_id:2017|Hs108|chr11 ( 513) 2574 306.9 3.9e-83 CCDS53676.1 CTTN gene_id:2017|Hs108|chr11 ( 634) 2489 297.3 3.7e-80 CCDS3003.1 HCLS1 gene_id:3059|Hs108|chr3 ( 486) 1111 140.1 5.8e-33 CCDS77800.1 HCLS1 gene_id:3059|Hs108|chr3 ( 449) 914 117.6 3.1e-26 >>CCDS41680.1 CTTN gene_id:2017|Hs108|chr11 (550 aa) initn: 3706 init1: 3706 opt: 3706 Z-score: 2303.0 bits: 435.9 E(32554): 5.9e-122 Smith-Waterman score: 3706; 100.0% identity (100.0% similar) in 550 aa overlap (1-550:1-550) 10 20 30 40 50 60 pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL 490 500 510 520 530 540 550 pF1KB3 FPANYVELRQ :::::::::: CCDS41 FPANYVELRQ 550 >>CCDS8197.1 CTTN gene_id:2017|Hs108|chr11 (513 aa) initn: 2739 init1: 2544 opt: 2574 Z-score: 1606.1 bits: 306.9 E(32554): 3.9e-83 Smith-Waterman score: 3375; 93.3% identity (93.3% similar) in 550 aa overlap (1-550:1-513) 10 20 30 40 50 60 pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ ::::::::::::::::::::::::: CCDS81 DRQDKCALGWDHQEKLQLHESQKDY----------------------------------- 250 260 310 320 330 340 350 360 pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 --SKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB3 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP 390 400 410 420 430 440 490 500 510 520 530 540 pF1KB3 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL 450 460 470 480 490 500 550 pF1KB3 FPANYVELRQ :::::::::: CCDS81 FPANYVELRQ 510 >>CCDS53676.1 CTTN gene_id:2017|Hs108|chr11 (634 aa) initn: 5172 init1: 2447 opt: 2489 Z-score: 1552.5 bits: 297.3 E(32554): 3.7e-80 Smith-Waterman score: 3290; 92.9% identity (93.1% similar) in 538 aa overlap (1-538:1-501) 10 20 30 40 50 60 pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ ::::::::::::::::::::::::: CCDS53 DRQDKCALGWDHQEKLQLHESQKDY----------------------------------- 250 260 310 320 330 340 350 360 pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 --SKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB3 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP 390 400 410 420 430 440 490 500 510 520 530 540 pF1KB3 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::. CCDS53 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRFRE 450 460 470 480 490 500 550 pF1KB3 FPANYVELRQ CCDS53 LAFSCVRVALVPIKCSRDLPGQARGLRSALWRVGRKDCPRRGASSRVSLLGRRGLGLMEV 510 520 530 540 550 560 >>CCDS3003.1 HCLS1 gene_id:3059|Hs108|chr3 (486 aa) initn: 1992 init1: 1049 opt: 1111 Z-score: 705.3 bits: 140.1 E(32554): 5.8e-33 Smith-Waterman score: 1349; 42.4% identity (65.9% similar) in 549 aa overlap (1-548:1-484) 10 20 30 40 50 60 pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE :::. .:: ::.. . : :::.::::::::.:::::::::::..:::. ::::::.::. CCDS30 MWKSVVGHDVSVSVETQG-DDWDTDPDFVNDISEKEQRWGAKTIEGSGRTEHINIHQLRN 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG .: .::..:..::.:.::::::::::.::::.:::::::::::: ... :: ::.:...: CCDS30 KVSEEHDVLRKKEMESGPKASHGYGGRFGVERDRMDKSAVGHEYVAEVEKHSSQTDAAKG 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG ::::.::. ::.:.:::::.:.:..:::.:::::: ::::.:::. :. ::.:.:.::.: CCDS30 FGGKYGVERDRADKSAVGFDYKGEVEKHTSQKDYSRGFGGRYGVEKDKWDKAALGYDYKG 120 130 140 150 160 170 190 200 210 220 230 pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGF-EYQGKTEKHESQKDYVKGFGGKFGVQ .::::::::::.:::::.:::.::.:::::::: :... : ... . .: :.. CCDS30 ETEKHESQRDYAKGFGGQYGIQKDRVDKSAVGFNEMEAPTTAYKKTTPIEAASSGTRGLK 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 TDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQ . .. .:: . .: .: . : ..:. :: : . . : CCDS30 AKFESMA------EEKRKREEEEKAQQ--------VARRQQERKAV-----TKRSPEAPQ 240 250 260 270 280 300 310 320 330 340 350 pF1KB3 QDYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAK . :.. : ..:: : . .:.. .:.. :. . CCDS30 PVIA-------------MEEPAVPAPLPKKISSEAWPPVGTPP-SSESEPVRTSREHPVP 290 300 310 320 360 370 380 390 400 410 pF1KB3 EKEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSP .. . :. . . : ... :: . : : :.: .. CCDS30 LLPIRQTLPEDNEEPPALPPRTLEGLQVE---EEPVYEAEPEPEPEPEPEPEND------ 330 340 350 360 370 420 430 440 450 460 470 pF1KB3 VYEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHY :::. :.. . : :: .::.:. . .... :. :. :. CCDS30 -YEDVE----EMDRHEQ----EDEP-----EGDYEEVLEPEDSSFSS-ALAGSSGCPAGA 380 390 400 410 420 480 490 500 510 520 530 pF1KB3 PAEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYG : . :::.:::.::::. :.::.::::::.::.:::.:.::::: :.:..: CCDS30 GAGAVA-------LGISAVAVYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHGHFG 430 440 450 460 470 540 550 pF1KB3 LFPANYVELRQ :::::::.: CCDS30 LFPANYVKLLE 480 >>CCDS77800.1 HCLS1 gene_id:3059|Hs108|chr3 (449 aa) initn: 1591 init1: 851 opt: 914 Z-score: 584.4 bits: 117.6 E(32554): 3.1e-26 Smith-Waterman score: 1095; 38.0% identity (61.1% similar) in 548 aa overlap (1-548:1-447) 10 20 30 40 50 60 pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE :::. .:: ::.. . : :::.::::::::.:::::::::::..:::. ::::::.::. CCDS77 MWKSVVGHDVSVSVETQG-DDWDTDPDFVNDISEKEQRWGAKTIEGSGRTEHINIHQLRN 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG .: .::..:..::.:.::::::::::.::::.:::::::::::: ... :: ::.:...: CCDS77 KVSEEHDVLRKKEMESGPKASHGYGGRFGVERDRMDKSAVGHEYVAEVEKHSSQTDAAKG 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG ::::.::. ::.:.:::::.:.:..:::.:::::..::::.::.: ::::::::::. CCDS77 FGGKYGVERDRADKSAVGFDYKGEVEKHTSQKDYAKGFGGQYGIQKDRVDKSAVGFN--- 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT ... ..... :: :. .. ..:. .:: .. CCDS77 ------------------------EMEAPTTAYK---KTTPIEAASSGTRGLKAKFESMA 180 190 200 250 260 270 280 290 300 pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ ... : ...:: : : ..:. :: : . . : CCDS77 EEKRK----REEEEKAQQ----------------VARRQQERKAV-----TKRSPEAPQP 210 220 230 240 310 320 330 340 350 360 pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE . :.. : ..:: : . .:.. .:.. :. . CCDS77 VIA-------------MEEPAVPAPLPKKISSEAWPPVGTPP-SSESEPVRTSREHPVPL 250 260 270 280 290 370 380 390 400 410 420 pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV .. . :. . . : ... :: . : : :.: .. CCDS77 LPIRQTLPEDNEEPPALPPRTLEGLQVE---EEPVYEAEPEPEPEPEPEPEND------- 300 310 320 330 340 430 440 450 460 470 480 pF1KB3 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP :::. :.. . : :: .::.:. . .... :. :. :. CCDS77 YEDVE----EMDRHEQ----EDEP-----EGDYEEVLEPEDSSFSS-ALAGSSGCPAGAG 350 360 370 380 490 500 510 520 530 540 pF1KB3 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL : . :::.:::.::::. :.::.::::::.::.:::.:.::::: :.:..:: CCDS77 AGAVA-------LGISAVAVYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHGHFGL 390 400 410 420 430 550 pF1KB3 FPANYVELRQ ::::::.: CCDS77 FPANYVKLLE 440 550 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:53:27 2016 done: Fri Nov 4 23:53:28 2016 Total Scan time: 2.840 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]