Result of FASTA (omim) for
pF1KB3103
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3103, 550 aa
1>>>pF1KB3103 550 - 550 aa - 550 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.8035+/-0.000491; mu= 0.2032+/- 0.031
mean_var=335.9925+/-69.931, 0's: 0 Z-trim(118.3): 110 B-trim: 47 in 1/59
Lambda= 0.069970
statistics sampled from 31089 (31209) to 31089 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.366), width: 16
Scan time: 9.910
The best scores are: opt bits E(85289)
NP_005222 (OMIM: 164765) src substrate cortactin i ( 550) 3706 388.3 3.3e-107
NP_612632 (OMIM: 164765) src substrate cortactin i ( 513) 2574 274.0 7.8e-73
NP_001171669 (OMIM: 164765) src substrate cortacti ( 634) 2489 265.5 3.4e-70
XP_006718511 (OMIM: 164765) PREDICTED: src substra ( 369) 2347 251.0 4.9e-66
XP_006718510 (OMIM: 164765) PREDICTED: src substra ( 476) 2333 249.7 1.6e-65
XP_016872801 (OMIM: 164765) PREDICTED: src substra ( 277) 1812 196.8 7.3e-50
NP_005326 (OMIM: 601306) hematopoietic lineage cel ( 486) 1111 126.3 2.1e-28
NP_001278970 (OMIM: 601306) hematopoietic lineage ( 449) 914 106.4 2e-22
NP_001271242 (OMIM: 610106) drebrin-like protein i ( 327) 317 46.0 0.00022
NP_001271244 (OMIM: 610106) drebrin-like protein i ( 336) 317 46.0 0.00022
NP_001014436 (OMIM: 610106) drebrin-like protein i ( 430) 317 46.1 0.00027
NP_054782 (OMIM: 610106) drebrin-like protein isof ( 431) 317 46.1 0.00027
XP_011513627 (OMIM: 610106) PREDICTED: drebrin-lik ( 438) 301 44.5 0.00082
NP_001116428 (OMIM: 610106) drebrin-like protein i ( 439) 301 44.5 0.00082
>>NP_005222 (OMIM: 164765) src substrate cortactin isofo (550 aa)
initn: 3706 init1: 3706 opt: 3706 Z-score: 2045.8 bits: 388.3 E(85289): 3.3e-107
Smith-Waterman score: 3706; 100.0% identity (100.0% similar) in 550 aa overlap (1-550:1-550)
10 20 30 40 50 60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
490 500 510 520 530 540
550
pF1KB3 FPANYVELRQ
::::::::::
NP_005 FPANYVELRQ
550
>>NP_612632 (OMIM: 164765) src substrate cortactin isofo (513 aa)
initn: 2739 init1: 2544 opt: 2574 Z-score: 1428.6 bits: 274.0 E(85289): 7.8e-73
Smith-Waterman score: 3375; 93.3% identity (93.3% similar) in 550 aa overlap (1-550:1-513)
10 20 30 40 50 60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
:::::::::::::::::::::::::
NP_612 DRQDKCALGWDHQEKLQLHESQKDY-----------------------------------
250 260
310 320 330 340 350 360
pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 --SKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB3 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
390 400 410 420 430 440
490 500 510 520 530 540
pF1KB3 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
450 460 470 480 490 500
550
pF1KB3 FPANYVELRQ
::::::::::
NP_612 FPANYVELRQ
510
>>NP_001171669 (OMIM: 164765) src substrate cortactin is (634 aa)
initn: 5172 init1: 2447 opt: 2489 Z-score: 1381.1 bits: 265.5 E(85289): 3.4e-70
Smith-Waterman score: 3290; 92.9% identity (93.1% similar) in 538 aa overlap (1-538:1-501)
10 20 30 40 50 60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
:::::::::::::::::::::::::
NP_001 DRQDKCALGWDHQEKLQLHESQKDY-----------------------------------
250 260
310 320 330 340 350 360
pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --SKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB3 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
390 400 410 420 430 440
490 500 510 520 530 540
pF1KB3 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_001 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRFRE
450 460 470 480 490 500
550
pF1KB3 FPANYVELRQ
NP_001 LAFSCVRVALVPIKCSRDLPGQARGLRSALWRVGRKDCPRRGASSRVSLLGRRGLGLMEV
510 520 530 540 550 560
>>XP_006718511 (OMIM: 164765) PREDICTED: src substrate c (369 aa)
initn: 2347 init1: 2347 opt: 2347 Z-score: 1306.5 bits: 251.0 E(85289): 4.9e-66
Smith-Waterman score: 2347; 100.0% identity (100.0% similar) in 345 aa overlap (1-345:1-345)
10 20 30 40 50 60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
:::::::::::::::::::::::::::::::::::::::::::::
XP_006 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSFWEQLGPAQLPEPLG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
XP_006 RSCDRRKTS
>>XP_006718510 (OMIM: 164765) PREDICTED: src substrate c (476 aa)
initn: 2459 init1: 2313 opt: 2333 Z-score: 1297.5 bits: 249.7 E(85289): 1.6e-65
Smith-Waterman score: 3033; 86.5% identity (86.5% similar) in 550 aa overlap (1-550:1-476)
10 20 30 40 50 60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDY------------
190 200 210 220
250 260 270 280 290 300
pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
XP_006 ------------------------------------------------------------
310 320 330 340 350 360
pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 --SKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
230 240 250 260 270 280
370 380 390 400 410 420
pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
290 300 310 320 330 340
430 440 450 460 470 480
pF1KB3 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
350 360 370 380 390 400
490 500 510 520 530 540
pF1KB3 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
410 420 430 440 450 460
550
pF1KB3 FPANYVELRQ
::::::::::
XP_006 FPANYVELRQ
470
>>XP_016872801 (OMIM: 164765) PREDICTED: src substrate c (277 aa)
initn: 1812 init1: 1812 opt: 1812 Z-score: 1016.2 bits: 196.8 E(85289): 7.3e-50
Smith-Waterman score: 1812; 100.0% identity (100.0% similar) in 263 aa overlap (1-263:1-263)
10 20 30 40 50 60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
:::::::::::::::::::::::
XP_016 DRQDKCALGWDHQEKLQLHESQKAREQTAIEPLFSAQ
250 260 270
>>NP_005326 (OMIM: 601306) hematopoietic lineage cell-sp (486 aa)
initn: 1996 init1: 1049 opt: 1111 Z-score: 630.7 bits: 126.3 E(85289): 2.1e-28
Smith-Waterman score: 1353; 42.6% identity (65.9% similar) in 549 aa overlap (1-548:1-484)
10 20 30 40 50 60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
:::. .:: ::.. . : :::.::::::::.:::::::::::..:::. ::::::.::.
NP_005 MWKSVVGHDVSVSVETQG-DDWDTDPDFVNDISEKEQRWGAKTIEGSGRTEHINIHQLRN
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
.: .::..:..::.:.::::::::::.::::.:::::::::::: ... :: ::.:...:
NP_005 KVSEEHDVLRKKEMESGPKASHGYGGRFGVERDRMDKSAVGHEYVAEVEKHSSQTDAAKG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
::::.::. ::.:.:::::.:.:..:::.:::::: ::::.:::. :. ::.:.:.::.:
NP_005 FGGKYGVERDRADKSAVGFDYKGEVEKHTSQKDYSRGFGGRYGVEKDKWDKAALGYDYKG
120 130 140 150 160 170
190 200 210 220 230
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGF-EYQGKTEKHESQKDYVKGFGGKFGVQ
.::::::::::.:::::.:::.::.:::::::: :... : ... . .: :..
NP_005 ETEKHESQRDYAKGFGGQYGIQKDRVDKSAVGFNEMEAPTTAYKKTTPIEAASSGTRGLK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB3 TDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQ
. .. .:: . .: .: . : ..:. :: : . . :
NP_005 AKFESMA------EEKRKREEEEKAQQ--------VARRQQERKAV-----TKRSPEAPQ
240 250 260 270 280
300 310 320 330 340 350
pF1KB3 QDYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAK
. :.. : ..:: : . .:.. .:.. :. .
NP_005 PVIA-------------MEEPAVPAPLPKKISSEAWPPVGTPP-SSESEPVRTSREHPVP
290 300 310 320
360 370 380 390 400 410
pF1KB3 EKEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSP
.. . :. . . : ... :: . : : :.: ..
NP_005 LLPIRQTLPEDNEEPPALPPRTLEGLQVE---EEPVYEAEPEPEPEPEPEPEND------
330 340 350 360 370
420 430 440 450 460 470
pF1KB3 VYEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHY
:::. :.. . : :: .::.:. . .... :. :. :.
NP_005 -YEDVE----EMDRHEQ----EDEP-----EGDYEEVLEPEDSSFSS-ALAGSSGCPAGA
380 390 400 410 420
480 490 500 510 520 530
pF1KB3 PAEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYG
: . :::.::::::::. :.::.::::::.::.:::.:.::::: :.:..:
NP_005 GAGAVA-------LGISAVALYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHGHFG
430 440 450 460 470
540 550
pF1KB3 LFPANYVELRQ
:::::::.:
NP_005 LFPANYVKLLE
480
>>NP_001278970 (OMIM: 601306) hematopoietic lineage cell (449 aa)
initn: 1595 init1: 851 opt: 914 Z-score: 523.7 bits: 106.4 E(85289): 2e-22
Smith-Waterman score: 1099; 38.1% identity (61.1% similar) in 548 aa overlap (1-548:1-447)
10 20 30 40 50 60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
:::. .:: ::.. . : :::.::::::::.:::::::::::..:::. ::::::.::.
NP_001 MWKSVVGHDVSVSVETQG-DDWDTDPDFVNDISEKEQRWGAKTIEGSGRTEHINIHQLRN
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
.: .::..:..::.:.::::::::::.::::.:::::::::::: ... :: ::.:...:
NP_001 KVSEEHDVLRKKEMESGPKASHGYGGRFGVERDRMDKSAVGHEYVAEVEKHSSQTDAAKG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
::::.::. ::.:.:::::.:.:..:::.:::::..::::.::.: ::::::::::.
NP_001 FGGKYGVERDRADKSAVGFDYKGEVEKHTSQKDYAKGFGGQYGIQKDRVDKSAVGFN---
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
... ..... :: :. .. ..:. .:: ..
NP_001 ------------------------EMEAPTTAYK---KTTPIEAASSGTRGLKAKFESMA
180 190 200
250 260 270 280 290 300
pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
... : ...:: : : ..:. :: : . . :
NP_001 EEKRK----REEEEKAQQ----------------VARRQQERKAV-----TKRSPEAPQP
210 220 230 240
310 320 330 340 350 360
pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
. :.. : ..:: : . .:.. .:.. :. .
NP_001 VIA-------------MEEPAVPAPLPKKISSEAWPPVGTPP-SSESEPVRTSREHPVPL
250 260 270 280 290
370 380 390 400 410 420
pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
.. . :. . . : ... :: . : : :.: ..
NP_001 LPIRQTLPEDNEEPPALPPRTLEGLQVE---EEPVYEAEPEPEPEPEPEPEND-------
300 310 320 330 340
430 440 450 460 470 480
pF1KB3 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
:::. :.. . : :: .::.:. . .... :. :. :.
NP_001 YEDVE----EMDRHEQ----EDEP-----EGDYEEVLEPEDSSFSS-ALAGSSGCPAGAG
350 360 370 380
490 500 510 520 530 540
pF1KB3 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
: . :::.::::::::. :.::.::::::.::.:::.:.::::: :.:..::
NP_001 AGAVA-------LGISAVALYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHGHFGL
390 400 410 420 430
550
pF1KB3 FPANYVELRQ
::::::.:
NP_001 FPANYVKLLE
440
>>NP_001271242 (OMIM: 610106) drebrin-like protein isofo (327 aa)
initn: 339 init1: 206 opt: 317 Z-score: 199.7 bits: 46.0 E(85289): 0.00022
Smith-Waterman score: 344; 32.6% identity (52.8% similar) in 307 aa overlap (303-548:30-325)
280 290 300 310 320
pF1KB3 FGVQSERQDSAAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDRMDKNASTFEDV---TQ
.:. :..:. .:. .. :.:: .
NP_001 MASFLKGAHVTINARAEEDVEPECIMEKVAKASGANYSFHKE-----SGRFQDVGPQAP
10 20 30 40 50
330 340 350 360 370 380
pF1KB3 VSSAYQKTVPVEAVTSKTSNIRANFENLAKEKEQEDRR---KAEAERAQR-MAKERQEQE
:.:.:::: .::. . .: : :::.:.:: : .::.::: . .::.:.:
NP_001 VGSVYQKT---NAVSEIKRVGKDSFWAKA-EKEEENRRLEEKRRAEEAQRQLEQERRERE
60 70 80 90 100 110
390 400
pF1KB3 ---EARRKLEEQARAKTQTPP--------------------VSP----------------
:::. . : .. .: : :
NP_001 LREAARREQRYQEQGGEASPQRTWEQQQEVVSRNRNEQESAVHPREIFKQKERAMSTTSI
120 130 140 150 160 170
410 420 430 440 450
pF1KB3 -APQPTEERLP------SSPV----YEDAASF---KAELSYRGPVSGTEPEPVYSMEAAD
.::: . : : ..: : ::.. .:.: . :. .: : : . : :
NP_001 SSPQPGKLRSPFLQKQLTQPETHFGREPAAAISRPRADLPAEEPAPSTPPCLVQAEEEAV
180 190 200 210 220 230
460 470 480 490 500 510
pF1KB3 YREASSQQGLAYATEAVYESAEAPGHYPAEDSTYDEYENDLGITAVALYDYQAAGDDEIS
:.: :. . : ... . : . . . :. : :::::::: : :::
NP_001 YEEPPEQETFYEQPPLVQQQGAGSEH--IDHHIQGQGLSGQGLCARALYDYQAADDTEIS
240 250 260 270 280
520 530 540 550
pF1KB3 FDPDDIITNIEMIDDGWWRGVCK-GRYGLFPANYVELRQ
:::...::.::.::.::::: :..:.::::::::
NP_001 FDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELIE
290 300 310 320
>>NP_001271244 (OMIM: 610106) drebrin-like protein isofo (336 aa)
initn: 339 init1: 206 opt: 317 Z-score: 199.6 bits: 46.0 E(85289): 0.00022
Smith-Waterman score: 342; 32.5% identity (52.6% similar) in 308 aa overlap (303-548:38-334)
280 290 300 310 320
pF1KB3 FGVQSERQDSAAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDRMDKNASTFEDV---TQ
.:. :..:. .:. .. :.:: .
NP_001 SAWLAQGGAHVTINARAEEDVEPECIMEKVAKASGANYSFHKE-----SGRFQDVGPQAP
10 20 30 40 50 60
330 340 350 360 370 380
pF1KB3 VSSAYQKTVPVEAVTSKTSNIRANFENLAKEKEQEDRR---KAEAERAQR-MAKERQEQE
:.:.:::: .::. . .: : :::.:.:: : .::.::: . .::.:.:
NP_001 VGSVYQKT---NAVSEIKRVGKDSFWAKA-EKEEENRRLEEKRRAEEAQRQLEQERRERE
70 80 90 100 110
390 400
pF1KB3 ---EARRKLEEQARAKTQTPP---------------------VSP---------------
:::. . : .. .: : :
NP_001 LREAARREQRYQEQGGEASPQSRTWEQQQEVVSRNRNEQESAVHPREIFKQKERAMSTTS
120 130 140 150 160 170
410 420 430 440 450
pF1KB3 --APQPTEERLP------SSPV----YEDAASF---KAELSYRGPVSGTEPEPVYSMEAA
.::: . : : ..: : ::.. .:.: . :. .: : : . : :
NP_001 ISSPQPGKLRSPFLQKQLTQPETHFGREPAAAISRPRADLPAEEPAPSTPPCLVQAEEEA
180 190 200 210 220 230
460 470 480 490 500 510
pF1KB3 DYREASSQQGLAYATEAVYESAEAPGHYPAEDSTYDEYENDLGITAVALYDYQAAGDDEI
:.: :. . : ... . : . . . :. : :::::::: : ::
NP_001 VYEEPPEQETFYEQPPLVQQQGAGSEH--IDHHIQGQGLSGQGLCARALYDYQAADDTEI
240 250 260 270 280 290
520 530 540 550
pF1KB3 SFDPDDIITNIEMIDDGWWRGVCK-GRYGLFPANYVELRQ
::::...::.::.::.::::: :..:.::::::::
NP_001 SFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELIE
300 310 320 330
550 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:53:28 2016 done: Fri Nov 4 23:53:29 2016
Total Scan time: 9.910 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]