FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3104, 803 aa 1>>>pF1KB3104 803 - 803 aa - 803 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0303+/-0.000419; mu= 22.0006+/- 0.026 mean_var=67.4325+/-13.776, 0's: 0 Z-trim(110.6): 80 B-trim: 488 in 1/52 Lambda= 0.156185 statistics sampled from 18910 (18992) to 18910 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.581), E-opt: 0.2 (0.223), width: 16 Scan time: 8.150 The best scores are: opt bits E(85289) NP_001927 (OMIM: 126141,612956,616311) dipeptidyl ( 803) 5350 1215.3 0 NP_570629 (OMIM: 126141,612956,616311) dipeptidyl ( 865) 5243 1191.2 0 NP_001034439 (OMIM: 126141,612956,616311) dipeptid ( 801) 5236 1189.6 0 XP_016867299 (OMIM: 126141,612956,616311) PREDICTE ( 804) 5235 1189.3 0 XP_016867297 (OMIM: 126141,612956,616311) PREDICTE ( 804) 5235 1189.3 0 XP_016867300 (OMIM: 126141,612956,616311) PREDICTE ( 804) 5235 1189.3 0 XP_016867298 (OMIM: 126141,612956,616311) PREDICTE ( 804) 5235 1189.3 0 XP_016867301 (OMIM: 126141,612956,616311) PREDICTE ( 657) 4414 1004.3 0 NP_001277181 (OMIM: 126141,612956,616311) dipeptid ( 758) 4092 931.8 0 NP_001171505 (OMIM: 608209) inactive dipeptidyl pe ( 800) 2902 663.7 9.1e-190 NP_001171508 (OMIM: 608209) inactive dipeptidyl pe ( 792) 2880 658.7 2.8e-188 NP_001004360 (OMIM: 608209) inactive dipeptidyl pe ( 789) 2873 657.1 8.3e-188 NP_001308835 (OMIM: 608209) inactive dipeptidyl pe ( 789) 2873 657.1 8.3e-188 NP_065919 (OMIM: 608209) inactive dipeptidyl pepti ( 796) 2871 656.7 1.1e-187 NP_001308834 (OMIM: 608209) inactive dipeptidyl pe ( 813) 2869 656.2 1.6e-187 NP_001171507 (OMIM: 608209) inactive dipeptidyl pe ( 746) 2709 620.1 1.1e-176 NP_001308839 (OMIM: 608209) inactive dipeptidyl pe ( 746) 2709 620.1 1.1e-176 NP_001308840 (OMIM: 608209) inactive dipeptidyl pe ( 746) 2709 620.1 1.1e-176 XP_016860055 (OMIM: 608209) PREDICTED: inactive di ( 755) 2681 613.8 8.5e-175 NP_001308837 (OMIM: 608209) inactive dipeptidyl pe ( 766) 2680 613.6 1e-174 NP_001308838 (OMIM: 608209) inactive dipeptidyl pe ( 757) 2563 587.3 8.6e-167 NP_001308841 (OMIM: 608209) inactive dipeptidyl pe ( 681) 2491 571.0 6e-162 NP_001308843 (OMIM: 608209) inactive dipeptidyl pe ( 542) 1971 453.8 9.4e-127 NP_001308842 (OMIM: 608209) inactive dipeptidyl pe ( 542) 1971 453.8 9.4e-127 XP_005246428 (OMIM: 102720) PREDICTED: dipeptidyl ( 765) 1542 357.2 1.6e-97 NP_004451 (OMIM: 600403) prolyl endopeptidase FAP ( 760) 1536 355.8 3.9e-97 NP_001926 (OMIM: 102720) dipeptidyl peptidase 4 [H ( 766) 1535 355.6 4.6e-97 XP_011509098 (OMIM: 600403) PREDICTED: prolyl endo ( 750) 1511 350.2 1.9e-95 XP_016860054 (OMIM: 608209) PREDICTED: inactive di ( 776) 1399 325.0 7.9e-88 NP_001308836 (OMIM: 608209) inactive dipeptidyl pe ( 783) 1396 324.3 1.3e-87 NP_001278736 (OMIM: 600403) prolyl endopeptidase F ( 735) 1384 321.6 7.9e-87 XP_011509099 (OMIM: 600403) PREDICTED: prolyl endo ( 491) 840 198.9 4.5e-50 NP_001277182 (OMIM: 126141,612956,616311) dipeptid ( 353) 832 197.0 1.2e-49 XP_016859074 (OMIM: 600403) PREDICTED: prolyl endo ( 475) 782 185.8 3.8e-46 XP_011526712 (OMIM: 608258) PREDICTED: dipeptidyl ( 863) 475 116.8 4.1e-25 XP_005259730 (OMIM: 608258) PREDICTED: dipeptidyl ( 892) 475 116.8 4.2e-25 NP_631898 (OMIM: 608258) dipeptidyl peptidase 9 [H ( 892) 475 116.8 4.2e-25 XP_011526710 (OMIM: 608258) PREDICTED: dipeptidyl ( 892) 475 116.8 4.2e-25 XP_011526707 (OMIM: 608258) PREDICTED: dipeptidyl ( 946) 475 116.8 4.4e-25 XP_016882943 (OMIM: 608258) PREDICTED: dipeptidyl ( 946) 475 116.8 4.4e-25 XP_011526708 (OMIM: 608258) PREDICTED: dipeptidyl ( 946) 475 116.8 4.4e-25 XP_016882942 (OMIM: 608258) PREDICTED: dipeptidyl ( 946) 475 116.8 4.4e-25 XP_005254562 (OMIM: 606819) PREDICTED: dipeptidyl ( 479) 470 115.5 5.6e-25 XP_016877871 (OMIM: 606819) PREDICTED: dipeptidyl ( 514) 470 115.5 5.9e-25 XP_016877872 (OMIM: 606819) PREDICTED: dipeptidyl ( 514) 470 115.5 5.9e-25 XP_016877866 (OMIM: 606819) PREDICTED: dipeptidyl ( 781) 470 115.7 8.2e-25 XP_011520035 (OMIM: 606819) PREDICTED: dipeptidyl ( 824) 470 115.7 8.5e-25 XP_016877864 (OMIM: 606819) PREDICTED: dipeptidyl ( 839) 470 115.7 8.6e-25 XP_011520033 (OMIM: 606819) PREDICTED: dipeptidyl ( 840) 470 115.7 8.7e-25 XP_011520032 (OMIM: 606819) PREDICTED: dipeptidyl ( 855) 470 115.7 8.8e-25 >>NP_001927 (OMIM: 126141,612956,616311) dipeptidyl amin (803 aa) initn: 5350 init1: 5350 opt: 5350 Z-score: 6509.0 bits: 1215.3 E(85289): 0 Smith-Waterman score: 5350; 99.9% identity (99.9% similar) in 803 aa overlap (1-803:1-803) 10 20 30 40 50 60 pF1KB3 MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 NSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 AHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 GPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSAS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 FSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEID 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 DYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 RGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYIL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 PAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 QFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINF 730 740 750 760 770 780 790 800 pF1KB3 FVECFRIQDKLPTVTAKEDEEED ::::::::::: ::::::::::: NP_001 FVECFRIQDKLLTVTAKEDEEED 790 800 >>NP_570629 (OMIM: 126141,612956,616311) dipeptidyl amin (865 aa) initn: 5241 init1: 5241 opt: 5243 Z-score: 6378.3 bits: 1191.2 E(85289): 0 Smith-Waterman score: 5243; 99.1% identity (99.6% similar) in 792 aa overlap (12-803:74-865) 10 20 30 40 pF1KB3 MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVI .: ..:.:::::::::::::::::::::: NP_570 LGPRAQAAAPRERGGGGGGAGGRPRFQYQARSDGDEEDELVGSNPPQRNWKGIAIALLVI 50 60 70 80 90 100 50 60 70 80 90 100 pF1KB3 LVICSLIVTSVILLTPAEDNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 LVICSLIVTSVILLTPAEDNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKG 110 120 130 140 150 160 110 120 130 140 150 160 pF1KB3 TVRLWNVETNTSTVLIEGKKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 TVRLWNVETNTSTVLIEGKKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSK 170 180 190 200 210 220 170 180 190 200 210 220 pF1KB3 IPHGDPQSLDPPEVSNAKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 IPHGDPQSLDPPEVSNAKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGV 230 240 250 260 270 280 230 240 250 260 270 280 pF1KB3 IYNGLSDWLYEEEILKTHIAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 IYNGLSDWLYEEEILKTHIAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYH 290 300 310 320 330 340 290 300 310 320 330 340 pF1KB3 YPKAGSENPSISLHVIGLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 YPKAGSENPSISLHVIGLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQ 350 360 370 380 390 400 350 360 370 380 390 400 pF1KB3 NVSILTLCDATTGVCTKKHEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 NVSILTLCDATTGVCTKKHEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHI 410 420 430 440 450 460 410 420 430 440 450 460 pF1KB3 TVSSSQPNSSNDNIQSITSGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 TVSSSQPNSSNDNIQSITSGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNF 470 480 490 500 510 520 470 480 490 500 510 520 pF1KB3 NRQCLSCDLVENCTYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 NRQCLSCDLVENCTYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVK 530 540 550 560 570 580 530 540 550 560 570 580 pF1KB3 KAINDRQMPKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 KAINDRQMPKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEV 590 600 610 620 630 640 590 600 610 620 630 640 pF1KB3 SWETVMVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 SWETVMVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDR 650 660 670 680 690 700 650 660 670 680 690 700 pF1KB3 TRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 TRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLD 710 720 730 740 750 760 710 720 730 740 750 760 pF1KB3 NRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 NRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDES 770 780 790 800 810 820 770 780 790 800 pF1KB3 HYFTSSSLKQHLYRSIINFFVECFRIQDKLPTVTAKEDEEED :::::::::::::::::::::::::::::: ::::::::::: NP_570 HYFTSSSLKQHLYRSIINFFVECFRIQDKLLTVTAKEDEEED 830 840 850 860 >>NP_001034439 (OMIM: 126141,612956,616311) dipeptidyl a (801 aa) initn: 5233 init1: 5233 opt: 5236 Z-score: 6370.2 bits: 1189.6 E(85289): 0 Smith-Waterman score: 5236; 99.2% identity (99.6% similar) in 790 aa overlap (14-803:12-801) 10 20 30 40 50 60 pF1KB3 MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAED .: . .::::::::::::::::::::::::::::::::::::::::: NP_001 MKEKAMIKTAKMQGNVMELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAED 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 NSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 KIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 QYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHI 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 AHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLN 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB3 GPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKH 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB3 EDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITS 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB3 GDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSAS 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB3 FSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEID 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB3 DYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDG 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB3 RGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYIL 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB3 PAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQ 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB3 QFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINF 720 730 740 750 760 770 790 800 pF1KB3 FVECFRIQDKLPTVTAKEDEEED ::::::::::: ::::::::::: NP_001 FVECFRIQDKLLTVTAKEDEEED 780 790 800 >>XP_016867299 (OMIM: 126141,612956,616311) PREDICTED: d (804 aa) initn: 5235 init1: 5235 opt: 5235 Z-score: 6369.0 bits: 1189.3 E(85289): 0 Smith-Waterman score: 5235; 99.7% identity (99.9% similar) in 785 aa overlap (19-803:20-804) 10 20 30 40 50 pF1KB3 MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE .:::::::::::::::::::::::::::::::::::::::: XP_016 MNQTAGVSNSVRCPPGKGHKELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB3 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB3 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB3 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN 730 740 750 760 770 780 780 790 800 pF1KB3 FFVECFRIQDKLPTVTAKEDEEED :::::::::::: ::::::::::: XP_016 FFVECFRIQDKLLTVTAKEDEEED 790 800 >>XP_016867297 (OMIM: 126141,612956,616311) PREDICTED: d (804 aa) initn: 5235 init1: 5235 opt: 5235 Z-score: 6369.0 bits: 1189.3 E(85289): 0 Smith-Waterman score: 5235; 99.7% identity (99.9% similar) in 785 aa overlap (19-803:20-804) 10 20 30 40 50 pF1KB3 MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE .:::::::::::::::::::::::::::::::::::::::: XP_016 MNQTAGVSNSVRCPPGKGHKELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB3 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB3 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB3 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN 730 740 750 760 770 780 780 790 800 pF1KB3 FFVECFRIQDKLPTVTAKEDEEED :::::::::::: ::::::::::: XP_016 FFVECFRIQDKLLTVTAKEDEEED 790 800 >>XP_016867300 (OMIM: 126141,612956,616311) PREDICTED: d (804 aa) initn: 5235 init1: 5235 opt: 5235 Z-score: 6369.0 bits: 1189.3 E(85289): 0 Smith-Waterman score: 5235; 99.7% identity (99.9% similar) in 785 aa overlap (19-803:20-804) 10 20 30 40 50 pF1KB3 MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE .:::::::::::::::::::::::::::::::::::::::: XP_016 MNQTAGVSNSVRCPPGKGHKELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB3 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB3 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB3 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN 730 740 750 760 770 780 780 790 800 pF1KB3 FFVECFRIQDKLPTVTAKEDEEED :::::::::::: ::::::::::: XP_016 FFVECFRIQDKLLTVTAKEDEEED 790 800 >>XP_016867298 (OMIM: 126141,612956,616311) PREDICTED: d (804 aa) initn: 5235 init1: 5235 opt: 5235 Z-score: 6369.0 bits: 1189.3 E(85289): 0 Smith-Waterman score: 5235; 99.7% identity (99.9% similar) in 785 aa overlap (19-803:20-804) 10 20 30 40 50 pF1KB3 MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE .:::::::::::::::::::::::::::::::::::::::: XP_016 MNQTAGVSNSVRCPPGKGHKELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB3 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB3 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB3 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN 730 740 750 760 770 780 780 790 800 pF1KB3 FFVECFRIQDKLPTVTAKEDEEED :::::::::::: ::::::::::: XP_016 FFVECFRIQDKLLTVTAKEDEEED 790 800 >>XP_016867301 (OMIM: 126141,612956,616311) PREDICTED: d (657 aa) initn: 4414 init1: 4414 opt: 4414 Z-score: 5370.4 bits: 1004.3 E(85289): 0 Smith-Waterman score: 4414; 99.8% identity (99.8% similar) in 656 aa overlap (148-803:2-657) 120 130 140 150 160 170 pF1KB3 EGKKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSN :::::::::::::::::::::::::::::: XP_016 MIYQHSYTGYYVLSKIPHGDPQSLDPPEVSN 10 20 30 180 190 200 210 220 230 pF1KB3 AKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILK 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB3 THIAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THIAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVI 100 110 120 130 140 150 300 310 320 330 340 350 pF1KB3 GLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCT 160 170 180 190 200 210 360 370 380 390 400 410 pF1KB3 KKHEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKHEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQS 220 230 240 250 260 270 420 430 440 450 460 470 pF1KB3 ITSGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITSGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYF 280 290 300 310 320 330 480 490 500 510 520 530 pF1KB3 SASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDI 340 350 360 370 380 390 540 550 560 570 580 590 pF1KB3 EIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVK 400 410 420 430 440 450 600 610 620 630 640 650 pF1KB3 CDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLST 460 470 480 490 500 510 660 670 680 690 700 710 pF1KB3 YILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSAL 520 530 540 550 560 570 720 730 740 750 760 770 pF1KB3 EEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSI 580 590 600 610 620 630 780 790 800 pF1KB3 INFFVECFRIQDKLPTVTAKEDEEED :::::::::::::: ::::::::::: XP_016 INFFVECFRIQDKLLTVTAKEDEEED 640 650 >>NP_001277181 (OMIM: 126141,612956,616311) dipeptidyl a (758 aa) initn: 4092 init1: 4092 opt: 4092 Z-score: 4977.4 bits: 931.8 E(85289): 0 Smith-Waterman score: 4928; 94.3% identity (94.3% similar) in 803 aa overlap (1-803:1-758) 10 20 30 40 50 60 pF1KB3 MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 NSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKL :::::::::::::::::::::::::::: NP_001 KIESLRAIRYEISPDREYALFSYNVEPI-------------------------------- 130 140 190 200 210 220 230 240 pF1KB3 QYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHI ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -------------FIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHI 150 160 170 180 190 250 260 270 280 290 300 pF1KB3 AHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLN 200 210 220 230 240 250 310 320 330 340 350 360 pF1KB3 GPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKH 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB3 EDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITS 320 330 340 350 360 370 430 440 450 460 470 480 pF1KB3 GDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSAS 380 390 400 410 420 430 490 500 510 520 530 540 pF1KB3 FSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEID 440 450 460 470 480 490 550 560 570 580 590 600 pF1KB3 DYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDG 500 510 520 530 540 550 610 620 630 640 650 660 pF1KB3 RGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYIL 560 570 580 590 600 610 670 680 690 700 710 720 pF1KB3 PAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQ 620 630 640 650 660 670 730 740 750 760 770 780 pF1KB3 QFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINF 680 690 700 710 720 730 790 800 pF1KB3 FVECFRIQDKLPTVTAKEDEEED ::::::::::: ::::::::::: NP_001 FVECFRIQDKLLTVTAKEDEEED 740 750 >>NP_001171505 (OMIM: 608209) inactive dipeptidyl peptid (800 aa) initn: 1987 init1: 1621 opt: 2902 Z-score: 3527.9 bits: 663.7 E(85289): 9.1e-190 Smith-Waterman score: 2902; 52.2% identity (80.3% similar) in 809 aa overlap (1-803:1-800) 10 20 30 40 50 pF1KB3 MTTAKE-----PSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILL ::.::. :.: ....: .::: ...::::::::::::::::::.::::. ::::: NP_001 MTAAKQEPQPTPGARASQAQPADQELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 TPAEDNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTV :: : .. :.. ....:::: .:: .:::::.::.::. .:. ..: : :.:::..:. NP_001 TPDELTN-SSETRLSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIETNATTL 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 LIEGKKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEV :.:. . ...: :. .::: .:.:..:.:. :...:::. ::. .: . :.:::: NP_001 LLENTTFVTFKASRHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 SNAKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEI .. ::::.:: .:::::.:::::::: . ....:..:.::: .:.::..:::::::. NP_001 EDSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEEIIFNGIADWLYEEEL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 LKTHIAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLH :..:::::::::: :::. :::: :: : .: .::..:: : : :::::. ::.:.:. NP_001 LHSHIAHWWSPDGERLAFLMINDSLVPTMVIPRFTGALYPKGKQYPYPKAGQVNPTIKLY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 VIGLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGV :..: :::: ::.::::. . ::::::::::...::..: :::::::.::::.:..:::. NP_001 VVNLYGPTHTLELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCETTTGA 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 CTKKHEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNI :.::.: :..:: .::::::::.:: :::. . :::::.:.::.. : .: . .. NP_001 CSKKYEMTSDTWLSQQNEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLIQSKSEQITV 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 QSITSGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLV-ENC . .:::.:.: ::::::: .::::::::. :: ::::::.: : .::::.::... :.: NP_001 RHLTSGNWEVIKILAYDETTQKIYFLSTESSPRGRQLYSASTEGLLNRQCISCNFMKEQC 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB3 TYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEY :::.:::: . ::: :::: ::.:..:.: . :.: ::.: .:.:: ... : : NP_001 TYFDASFSPMNQHFLLFCEGPRVPVVSLHSTDNPAKYFILESNSMLKEAILKKKIGKPEI 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB3 RDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAV . ..::::.::.:. : : : ..: :::..: ::.: :..::...:..:... ... NP_001 KILHIDDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQLVTDKFHIDWDSVLIDMDNVI 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB3 VVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGY :.. ::::::::: :.:.:..:::: .: :::. ::. .:: ::: :...::: :::: NP_001 VARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGY 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 LSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRV ....:: ... . : :::...::::.:::::::::::::. . .. .:. ..: : : NP_001 IASMIL----KSDEKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEESTYQAASVLHNV 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB3 SALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLY .:.:...:::: ::: :.::::.:::: .::.. .::..:.::::.: . .: : ::: NP_001 HGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSEKS-KYHLY 720 730 740 750 760 770 780 790 800 pF1KB3 RSIINFFVECFRIQDKLPTVTAKEDEEED .:..:: .:.. . .: .: ::.. NP_001 STILKFFSDCLK---EEISVLPQEPEEDE 780 790 800 803 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:25:11 2016 done: Thu Nov 3 12:25:12 2016 Total Scan time: 8.150 Total Display time: 0.240 Function used was FASTA [36.3.4 Apr, 2011]