FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3105, 164 aa 1>>>pF1KB3105 164 - 164 aa - 164 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1941+/-0.000312; mu= 5.7354+/- 0.020 mean_var=239.6198+/-50.663, 0's: 0 Z-trim(123.8): 125 B-trim: 1614 in 1/58 Lambda= 0.082854 statistics sampled from 44012 (44205) to 44012 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.831), E-opt: 0.2 (0.518), width: 16 Scan time: 6.080 The best scores are: opt bits E(85289) NP_003008 (OMIM: 603364) serine/arginine-rich spli ( 164) 1157 149.7 1.9e-36 XP_005264542 (OMIM: 600572) PREDICTED: serine/argi ( 223) 557 78.2 9.1e-15 NP_001182375 (OMIM: 600572) serine/arginine-rich s ( 226) 557 78.2 9.2e-15 XP_005264541 (OMIM: 600572) PREDICTED: serine/argi ( 235) 557 78.2 9.4e-15 NP_001026854 (OMIM: 600572) serine/arginine-rich s ( 238) 557 78.2 9.4e-15 NP_006616 (OMIM: 605221) serine/arginine-rich spli ( 183) 334 51.4 8.5e-07 NP_001287866 (OMIM: 605221) serine/arginine-rich s ( 217) 334 51.5 9.5e-07 NP_473357 (OMIM: 605221) serine/arginine-rich spli ( 262) 334 51.6 1.1e-06 NP_001177935 (OMIM: 605221) serine/arginine-rich s ( 173) 331 51.0 1.1e-06 NP_001287865 (OMIM: 605221) serine/arginine-rich s ( 172) 326 50.4 1.6e-06 NP_001177936 (OMIM: 605221) serine/arginine-rich s ( 182) 323 50.1 2.1e-06 NP_001177934 (OMIM: 605221) serine/arginine-rich s ( 261) 323 50.3 2.6e-06 NP_001177938 (OMIM: 605221) serine/arginine-rich s ( 165) 309 48.4 6.4e-06 XP_016872631 (OMIM: 603269) PREDICTED: serine/argi ( 282) 294 46.9 3e-05 NP_115285 (OMIM: 603269) serine/arginine-rich spli ( 282) 294 46.9 3e-05 XP_005268057 (OMIM: 600914) PREDICTED: serine/argi ( 271) 291 46.5 3.8e-05 XP_016877082 (OMIM: 600914) PREDICTED: serine/argi ( 271) 291 46.5 3.8e-05 XP_005268056 (OMIM: 600914) PREDICTED: serine/argi ( 271) 291 46.5 3.8e-05 NP_001307143 (OMIM: 600914) serine/arginine-rich s ( 272) 291 46.5 3.8e-05 NP_008856 (OMIM: 600914) serine/arginine-rich spli ( 272) 291 46.5 3.8e-05 NP_001034554 (OMIM: 600914) serine/arginine-rich s ( 272) 291 46.5 3.8e-05 NP_001071634 (OMIM: 600812) serine/arginine-rich s ( 201) 257 42.3 0.00053 NP_008855 (OMIM: 600812) serine/arginine-rich spli ( 248) 257 42.4 0.0006 XP_011535379 (OMIM: 600914) PREDICTED: serine/argi ( 239) 237 40.0 0.0031 NP_006266 (OMIM: 601944) serine/arginine-rich spli ( 344) 234 39.8 0.0049 XP_011540253 (OMIM: 601940) PREDICTED: serine/argi ( 464) 229 39.4 0.0089 NP_005617 (OMIM: 601940) serine/arginine-rich spli ( 494) 229 39.4 0.0093 >>NP_003008 (OMIM: 603364) serine/arginine-rich splicing (164 aa) initn: 1157 init1: 1157 opt: 1157 Z-score: 775.2 bits: 149.7 E(85289): 1.9e-36 Smith-Waterman score: 1157; 100.0% identity (100.0% similar) in 164 aa overlap (1-164:1-164) 10 20 30 40 50 60 pF1KB3 MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRS 70 80 90 100 110 120 130 140 150 160 pF1KB3 FSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK :::::::::::::::::::::::::::::::::::::::::::: NP_003 FSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK 130 140 150 160 >>XP_005264542 (OMIM: 600572) PREDICTED: serine/arginine (223 aa) initn: 977 init1: 427 opt: 557 Z-score: 386.1 bits: 78.2 E(85289): 9.1e-15 Smith-Waterman score: 557; 60.0% identity (72.7% similar) in 165 aa overlap (9-163:10-170) 10 20 30 40 50 pF1KB3 MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDA . ::::::::....: ::::::.::::::.::.:::::::::::::::::: XP_005 MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDA 10 20 30 40 50 60 60 70 80 90 100 pF1KB3 ADAVRELDGRTLCGCRVRVELSNG-EKRSRNRGPPPSWGRRPRDDYRR---------RSP :::: :::...:: :::::::.: .::: :: .::: : : . XP_005 EDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPP---ARRPFDPNDRCYECGEKGHYAY 70 80 90 100 110 110 120 130 140 150 160 pF1KB3 PPRRRSPRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK .: : :::: :::::.: :: :: :: :: :... ::: : :::: : .: XP_005 DCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRR-SRSASPRRSRSISLRRSRSASL 120 130 140 150 160 170 XP_005 RRSRSGSIKGSRSPSRSRSRSRSISRPRSSRSPSGSPRRSASPERMD 180 190 200 210 220 >>NP_001182375 (OMIM: 600572) serine/arginine-rich splic (226 aa) initn: 806 init1: 427 opt: 557 Z-score: 386.1 bits: 78.2 E(85289): 9.2e-15 Smith-Waterman score: 557; 60.0% identity (72.7% similar) in 165 aa overlap (9-163:10-170) 10 20 30 40 50 pF1KB3 MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDA . ::::::::....: ::::::.::::::.::.:::::::::::::::::: NP_001 MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDA 10 20 30 40 50 60 60 70 80 90 100 pF1KB3 ADAVRELDGRTLCGCRVRVELSNG-EKRSRNRGPPPSWGRRPRDDYRR---------RSP :::: :::...:: :::::::.: .::: :: .::: : : . NP_001 EDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPP---ARRPFDPNDRCYECGEKGHYAY 70 80 90 100 110 110 120 130 140 150 160 pF1KB3 PPRRRSPRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK .: : :::: :::::.: :: :: :: :: :... ::: : :::: : .: NP_001 DCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRR-SRSASPRRSRSISLRRSRSASL 120 130 140 150 160 170 NP_001 RRSRSGSIKGSRYFQSPSRSRSRSRSISRPRSSRSPSGSPRRSASPERMD 180 190 200 210 220 >>XP_005264541 (OMIM: 600572) PREDICTED: serine/arginine (235 aa) initn: 1072 init1: 427 opt: 557 Z-score: 385.9 bits: 78.2 E(85289): 9.4e-15 Smith-Waterman score: 557; 60.0% identity (72.7% similar) in 165 aa overlap (9-163:10-170) 10 20 30 40 50 pF1KB3 MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDA . ::::::::....: ::::::.::::::.::.:::::::::::::::::: XP_005 MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDA 10 20 30 40 50 60 60 70 80 90 100 pF1KB3 ADAVRELDGRTLCGCRVRVELSNG-EKRSRNRGPPPSWGRRPRDDYRR---------RSP :::: :::...:: :::::::.: .::: :: .::: : : . XP_005 EDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPP---ARRPFDPNDRCYECGEKGHYAY 70 80 90 100 110 110 120 130 140 150 160 pF1KB3 PPRRRSPRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK .: : :::: :::::.: :: :: :: :: :... ::: : :::: : .: XP_005 DCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRR-SRSASPRRSRSISLRRSRSASL 120 130 140 150 160 170 XP_005 RRSRSGSIKGSRSPSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPRRSASPERMD 180 190 200 210 220 230 >>NP_001026854 (OMIM: 600572) serine/arginine-rich splic (238 aa) initn: 769 init1: 427 opt: 557 Z-score: 385.8 bits: 78.2 E(85289): 9.4e-15 Smith-Waterman score: 557; 60.0% identity (72.7% similar) in 165 aa overlap (9-163:10-170) 10 20 30 40 50 pF1KB3 MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDA . ::::::::....: ::::::.::::::.::.:::::::::::::::::: NP_001 MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDA 10 20 30 40 50 60 60 70 80 90 100 pF1KB3 ADAVRELDGRTLCGCRVRVELSNG-EKRSRNRGPPPSWGRRPRDDYRR---------RSP :::: :::...:: :::::::.: .::: :: .::: : : . NP_001 EDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPP---ARRPFDPNDRCYECGEKGHYAY 70 80 90 100 110 110 120 130 140 150 160 pF1KB3 PPRRRSPRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK .: : :::: :::::.: :: :: :: :: :... ::: : :::: : .: NP_001 DCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRR-SRSASPRRSRSISLRRSRSASL 120 130 140 150 160 170 NP_001 RRSRSGSIKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPRRSASPER 180 190 200 210 220 230 >>NP_006616 (OMIM: 605221) serine/arginine-rich splicing (183 aa) initn: 488 init1: 178 opt: 334 Z-score: 243.0 bits: 51.4 E(85289): 8.5e-07 Smith-Waterman score: 334; 37.5% identity (64.3% similar) in 168 aa overlap (1-163:1-164) 10 20 30 40 50 pF1KB3 MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWV-----ARNPPGFAFVEFED : : : . ...: :.... . .:.: :: :::. .:.: .: : :::.:.::: NP_006 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 PRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRS ::: ::...:: . .:: ........:.... :. :: .. : . ::: NP_006 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKE-GRNVYSSSRYDDYDRYRRS 70 80 90 100 110 120 130 140 150 160 pF1KB3 PRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK : ::. : :::: : : .:: : :: .:. ::::.: .:.: NP_006 -RSRSYERRRSRSRSFDYNYRRSYS-PRNSRPTGRPRRSRSHS-DNDRPNCSWNTQYSSA 120 130 140 150 160 170 NP_006 YYTSRKI 180 >>NP_001287866 (OMIM: 605221) serine/arginine-rich splic (217 aa) initn: 621 init1: 178 opt: 334 Z-score: 242.2 bits: 51.5 E(85289): 9.5e-07 Smith-Waterman score: 334; 37.5% identity (64.3% similar) in 168 aa overlap (1-163:1-164) 10 20 30 40 50 pF1KB3 MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWV-----ARNPPGFAFVEFED : : : . ...: :.... . .:.: :: :::. .:.: .: : :::.:.::: NP_001 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 PRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRS ::: ::...:: . .:: ........:.... :. :: .. : . ::: NP_001 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKE-GRNVYSSSRYDDYDRYRRS 70 80 90 100 110 120 130 140 150 160 pF1KB3 PRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK : ::. : :::: : : .:: : :: .:. ::::.: .:.: NP_001 -RSRSYERRRSRSRSFDYNYRRSYS-PRNSRPTGRPRRSRSHS-DNDRFKHRNRSFSRSK 120 130 140 150 160 170 NP_001 SNSRSRSKSQPKKEMKAKSRSRPNCSWNTQYSSAYYTSRKI 180 190 200 210 >>NP_473357 (OMIM: 605221) serine/arginine-rich splicing (262 aa) initn: 626 init1: 178 opt: 334 Z-score: 241.3 bits: 51.6 E(85289): 1.1e-06 Smith-Waterman score: 334; 37.5% identity (64.3% similar) in 168 aa overlap (1-163:1-164) 10 20 30 40 50 pF1KB3 MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWV-----ARNPPGFAFVEFED : : : . ...: :.... . .:.: :: :::. .:.: .: : :::.:.::: NP_473 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 PRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRS ::: ::...:: . .:: ........:.... :. :: .. : . ::: NP_473 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKE-GRNVYSSSRYDDYDRYRRS 70 80 90 100 110 120 130 140 150 160 pF1KB3 PRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK : ::. : :::: : : .:: : :: .:. ::::.: .:.: NP_473 -RSRSYERRRSRSRSFDYNYRRSYS-PRNSRPTGRPRRSRSHS-DNDRFKHRNRSFSRSK 120 130 140 150 160 170 NP_473 SNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSK 180 190 200 210 220 230 >>NP_001177935 (OMIM: 605221) serine/arginine-rich splic (173 aa) initn: 488 init1: 178 opt: 331 Z-score: 241.3 bits: 51.0 E(85289): 1.1e-06 Smith-Waterman score: 331; 36.7% identity (63.9% similar) in 166 aa overlap (1-161:1-163) 10 20 30 40 50 pF1KB3 MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWV-----ARNPPGFAFVEFED : : : . ...: :.... . .:.: :: :::. .:.: .: : :::.:.::: NP_001 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 PRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRS ::: ::...:: . .:: ........:.... :. :: .. : . ::: NP_001 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKE-GRNVYSSSRYDDYDRYRRS 70 80 90 100 110 120 130 140 150 160 pF1KB3 PRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK : ::. : :::: : : .:: : :: .:. ::::.: .. NP_001 -RSRSYERRRSRSRSFDYNYRRSYS-PRNSRPTGRPRRSRSHSDNDSQVSKKKNER 120 130 140 150 160 170 >>NP_001287865 (OMIM: 605221) serine/arginine-rich splic (172 aa) initn: 393 init1: 210 opt: 326 Z-score: 238.1 bits: 50.4 E(85289): 1.6e-06 Smith-Waterman score: 326; 36.3% identity (64.9% similar) in 171 aa overlap (1-164:1-169) 10 20 30 40 50 pF1KB3 MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWV-----ARNPPGFAFVEFED : : : . ...: :.... . .:.: :: :::. .:.: .: : :::.:.::: NP_001 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 PRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRS ::: ::...:: . .:: ........:.... :. :: .. : . ::: NP_001 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKE-GRNVYSSSRYDDYDRYRRS 70 80 90 100 110 120 130 140 150 160 pF1KB3 PRRRSFSRSRSRSLSRDRRRERSLS-RER-NHKPSRSFSRSRSRSRSNERK : ::. : :::: : : .:: : :.: . .: :: :.: . :. ...: NP_001 -RSRSYERRRSRSRSFDYNYRRSYSPRNRPTGRPRRSRSHSDNDSQVSKKKNER 120 130 140 150 160 170 164 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:16:38 2016 done: Fri Nov 4 21:16:39 2016 Total Scan time: 6.080 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]