FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3106, 837 aa 1>>>pF1KB3106 837 - 837 aa - 837 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6237+/-0.000433; mu= 15.3237+/- 0.027 mean_var=121.6895+/-24.531, 0's: 0 Z-trim(113.6): 62 B-trim: 301 in 1/55 Lambda= 0.116265 statistics sampled from 22989 (23046) to 22989 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.27), width: 16 Scan time: 12.940 The best scores are: opt bits E(85289) NP_036275 (OMIM: 612747) tuftelin-interacting prot ( 837) 5739 974.7 0 XP_016884224 (OMIM: 612747) PREDICTED: tuftelin-in ( 837) 5739 974.7 0 XP_011528381 (OMIM: 612747) PREDICTED: tuftelin-in ( 837) 5739 974.7 0 NP_001008697 (OMIM: 612747) tuftelin-interacting p ( 837) 5739 974.7 0 XP_011542291 (OMIM: 300080,311900) PREDICTED: RNA- ( 618) 183 42.7 0.0062 XP_016885374 (OMIM: 300080,311900) PREDICTED: RNA- ( 726) 183 42.7 0.0071 XP_006724626 (OMIM: 300080,311900) PREDICTED: RNA- ( 727) 183 42.7 0.0071 XP_016885373 (OMIM: 300080,311900) PREDICTED: RNA- ( 727) 183 42.7 0.0071 NP_690595 (OMIM: 300080,311900) RNA-binding protei ( 852) 183 42.8 0.008 NP_001191395 (OMIM: 300080,311900) RNA-binding pro ( 853) 183 42.8 0.008 XP_005272736 (OMIM: 300080,311900) PREDICTED: RNA- ( 917) 183 42.8 0.0084 XP_005272735 (OMIM: 300080,311900) PREDICTED: RNA- ( 918) 183 42.8 0.0085 NP_001191396 (OMIM: 300080,311900) RNA-binding pro ( 929) 183 42.8 0.0085 NP_005667 (OMIM: 300080,311900) RNA-binding protei ( 930) 183 42.8 0.0085 XP_005272734 (OMIM: 300080,311900) PREDICTED: RNA- ( 994) 183 42.8 0.009 NP_001191397 (OMIM: 300080,311900) RNA-binding pro ( 995) 183 42.8 0.009 >>NP_036275 (OMIM: 612747) tuftelin-interacting protein (837 aa) initn: 5739 init1: 5739 opt: 5739 Z-score: 5208.4 bits: 974.7 E(85289): 0 Smith-Waterman score: 5739; 100.0% identity (100.0% similar) in 837 aa overlap (1-837:1-837) 10 20 30 40 50 60 pF1KB3 MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDSDDEEKPVKQDDFPKDFGPRKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 DERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDSDDEEKPVKQDDFPKDFGPRKLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 AKQRKGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEEFQKELSQWRKDPSGSKKKPKYSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 AKQRKGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEEFQKELSQWRKDPSGSKKKPKYSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 KTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQKVYYSYSQISHKHNVPDDGLPLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 KTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQKVYYSYSQISHKHNVPDDGLPLQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 QQLPQSGKEAKAPGFALPELEHNLQLLIDLTEQEIIQNDRQLQYERDMVVNLFHELEKMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 QQLPQSGKEAKAPGFALPELEHNLQLLIDLTEQEIIQNDRQLQYERDMVVNLFHELEKMT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EVLDHEERVISNLSKVLEMVEECERRMQPDCSNPLTLDECARIFETLQDKYYEEYRMSDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EVLDHEERVISNLSKVLEMVEECERRMQPDCSNPLTLDECARIFETLQDKYYEEYRMSDR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 VDLAVAIVYPLMKEYFKEWDPLKDCTYGTEIISKWKSLLENDQLLSHGGQDLSADAFHRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VDLAVAIVYPLMKEYFKEWDPLKDCTYGTEIISKWKSLLENDQLLSHGGQDLSADAFHRL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 IWEVWMPFVRNIVTQWQPRNCDPMVDFLDSWVHIIPVWILDNILDQLIFPKLQKEVENWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 IWEVWMPFVRNIVTQWQPRNCDPMVDFLDSWVHIIPVWILDNILDQLIFPKLQKEVENWN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 PLTDTVPIHSWIHPWLPLMQARLEPLYSPIRSKLSSALQKWHPSDSSAKLILQPWKDVFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PLTDTVPIHSWIHPWLPLMQARLEPLYSPIRSKLSSALQKWHPSDSSAKLILQPWKDVFT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 PGSWEAFMVKNIVPKLGMCLGELVINPHQQHMDAFYWVIDWEGMISVSSLVGLLEKHFFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PGSWEAFMVKNIVPKLGMCLGELVINPHQQHMDAFYWVIDWEGMISVSSLVGLLEKHFFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 KWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 KWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 AYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASSVPMNFKDLIETK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 AYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASSVPMNFKDLIETK 730 740 750 760 770 780 790 800 810 820 830 pF1KB3 AEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGEKTWVPTSLQSLIDMAK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 AEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGEKTWVPTSLQSLIDMAK 790 800 810 820 830 >>XP_016884224 (OMIM: 612747) PREDICTED: tuftelin-intera (837 aa) initn: 5739 init1: 5739 opt: 5739 Z-score: 5208.4 bits: 974.7 E(85289): 0 Smith-Waterman score: 5739; 100.0% identity (100.0% similar) in 837 aa overlap (1-837:1-837) 10 20 30 40 50 60 pF1KB3 MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDSDDEEKPVKQDDFPKDFGPRKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDSDDEEKPVKQDDFPKDFGPRKLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 AKQRKGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEEFQKELSQWRKDPSGSKKKPKYSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKQRKGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEEFQKELSQWRKDPSGSKKKPKYSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 KTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQKVYYSYSQISHKHNVPDDGLPLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQKVYYSYSQISHKHNVPDDGLPLQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 QQLPQSGKEAKAPGFALPELEHNLQLLIDLTEQEIIQNDRQLQYERDMVVNLFHELEKMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQLPQSGKEAKAPGFALPELEHNLQLLIDLTEQEIIQNDRQLQYERDMVVNLFHELEKMT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EVLDHEERVISNLSKVLEMVEECERRMQPDCSNPLTLDECARIFETLQDKYYEEYRMSDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVLDHEERVISNLSKVLEMVEECERRMQPDCSNPLTLDECARIFETLQDKYYEEYRMSDR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 VDLAVAIVYPLMKEYFKEWDPLKDCTYGTEIISKWKSLLENDQLLSHGGQDLSADAFHRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDLAVAIVYPLMKEYFKEWDPLKDCTYGTEIISKWKSLLENDQLLSHGGQDLSADAFHRL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 IWEVWMPFVRNIVTQWQPRNCDPMVDFLDSWVHIIPVWILDNILDQLIFPKLQKEVENWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IWEVWMPFVRNIVTQWQPRNCDPMVDFLDSWVHIIPVWILDNILDQLIFPKLQKEVENWN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 PLTDTVPIHSWIHPWLPLMQARLEPLYSPIRSKLSSALQKWHPSDSSAKLILQPWKDVFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLTDTVPIHSWIHPWLPLMQARLEPLYSPIRSKLSSALQKWHPSDSSAKLILQPWKDVFT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 PGSWEAFMVKNIVPKLGMCLGELVINPHQQHMDAFYWVIDWEGMISVSSLVGLLEKHFFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGSWEAFMVKNIVPKLGMCLGELVINPHQQHMDAFYWVIDWEGMISVSSLVGLLEKHFFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 KWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 AYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASSVPMNFKDLIETK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASSVPMNFKDLIETK 730 740 750 760 770 780 790 800 810 820 830 pF1KB3 AEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGEKTWVPTSLQSLIDMAK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGEKTWVPTSLQSLIDMAK 790 800 810 820 830 >>XP_011528381 (OMIM: 612747) PREDICTED: tuftelin-intera (837 aa) initn: 5739 init1: 5739 opt: 5739 Z-score: 5208.4 bits: 974.7 E(85289): 0 Smith-Waterman score: 5739; 100.0% identity (100.0% similar) in 837 aa overlap (1-837:1-837) 10 20 30 40 50 60 pF1KB3 MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDSDDEEKPVKQDDFPKDFGPRKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDSDDEEKPVKQDDFPKDFGPRKLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 AKQRKGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEEFQKELSQWRKDPSGSKKKPKYSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKQRKGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEEFQKELSQWRKDPSGSKKKPKYSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 KTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQKVYYSYSQISHKHNVPDDGLPLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQKVYYSYSQISHKHNVPDDGLPLQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 QQLPQSGKEAKAPGFALPELEHNLQLLIDLTEQEIIQNDRQLQYERDMVVNLFHELEKMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQLPQSGKEAKAPGFALPELEHNLQLLIDLTEQEIIQNDRQLQYERDMVVNLFHELEKMT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EVLDHEERVISNLSKVLEMVEECERRMQPDCSNPLTLDECARIFETLQDKYYEEYRMSDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVLDHEERVISNLSKVLEMVEECERRMQPDCSNPLTLDECARIFETLQDKYYEEYRMSDR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 VDLAVAIVYPLMKEYFKEWDPLKDCTYGTEIISKWKSLLENDQLLSHGGQDLSADAFHRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDLAVAIVYPLMKEYFKEWDPLKDCTYGTEIISKWKSLLENDQLLSHGGQDLSADAFHRL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 IWEVWMPFVRNIVTQWQPRNCDPMVDFLDSWVHIIPVWILDNILDQLIFPKLQKEVENWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IWEVWMPFVRNIVTQWQPRNCDPMVDFLDSWVHIIPVWILDNILDQLIFPKLQKEVENWN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 PLTDTVPIHSWIHPWLPLMQARLEPLYSPIRSKLSSALQKWHPSDSSAKLILQPWKDVFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLTDTVPIHSWIHPWLPLMQARLEPLYSPIRSKLSSALQKWHPSDSSAKLILQPWKDVFT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 PGSWEAFMVKNIVPKLGMCLGELVINPHQQHMDAFYWVIDWEGMISVSSLVGLLEKHFFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGSWEAFMVKNIVPKLGMCLGELVINPHQQHMDAFYWVIDWEGMISVSSLVGLLEKHFFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 KWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 AYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASSVPMNFKDLIETK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASSVPMNFKDLIETK 730 740 750 760 770 780 790 800 810 820 830 pF1KB3 AEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGEKTWVPTSLQSLIDMAK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGEKTWVPTSLQSLIDMAK 790 800 810 820 830 >>NP_001008697 (OMIM: 612747) tuftelin-interacting prote (837 aa) initn: 5739 init1: 5739 opt: 5739 Z-score: 5208.4 bits: 974.7 E(85289): 0 Smith-Waterman score: 5739; 100.0% identity (100.0% similar) in 837 aa overlap (1-837:1-837) 10 20 30 40 50 60 pF1KB3 MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDSDDEEKPVKQDDFPKDFGPRKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDSDDEEKPVKQDDFPKDFGPRKLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 AKQRKGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEEFQKELSQWRKDPSGSKKKPKYSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKQRKGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEEFQKELSQWRKDPSGSKKKPKYSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 KTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQKVYYSYSQISHKHNVPDDGLPLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQKVYYSYSQISHKHNVPDDGLPLQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 QQLPQSGKEAKAPGFALPELEHNLQLLIDLTEQEIIQNDRQLQYERDMVVNLFHELEKMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQLPQSGKEAKAPGFALPELEHNLQLLIDLTEQEIIQNDRQLQYERDMVVNLFHELEKMT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EVLDHEERVISNLSKVLEMVEECERRMQPDCSNPLTLDECARIFETLQDKYYEEYRMSDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVLDHEERVISNLSKVLEMVEECERRMQPDCSNPLTLDECARIFETLQDKYYEEYRMSDR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 VDLAVAIVYPLMKEYFKEWDPLKDCTYGTEIISKWKSLLENDQLLSHGGQDLSADAFHRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDLAVAIVYPLMKEYFKEWDPLKDCTYGTEIISKWKSLLENDQLLSHGGQDLSADAFHRL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 IWEVWMPFVRNIVTQWQPRNCDPMVDFLDSWVHIIPVWILDNILDQLIFPKLQKEVENWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IWEVWMPFVRNIVTQWQPRNCDPMVDFLDSWVHIIPVWILDNILDQLIFPKLQKEVENWN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 PLTDTVPIHSWIHPWLPLMQARLEPLYSPIRSKLSSALQKWHPSDSSAKLILQPWKDVFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLTDTVPIHSWIHPWLPLMQARLEPLYSPIRSKLSSALQKWHPSDSSAKLILQPWKDVFT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 PGSWEAFMVKNIVPKLGMCLGELVINPHQQHMDAFYWVIDWEGMISVSSLVGLLEKHFFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGSWEAFMVKNIVPKLGMCLGELVINPHQQHMDAFYWVIDWEGMISVSSLVGLLEKHFFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 KWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 AYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASSVPMNFKDLIETK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASSVPMNFKDLIETK 730 740 750 760 770 780 790 800 810 820 830 pF1KB3 AEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGEKTWVPTSLQSLIDMAK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGEKTWVPTSLQSLIDMAK 790 800 810 820 830 >>XP_011542291 (OMIM: 300080,311900) PREDICTED: RNA-bind (618 aa) initn: 177 init1: 150 opt: 183 Z-score: 173.6 bits: 42.7 E(85289): 0.0062 Smith-Waterman score: 184; 28.3% identity (56.6% similar) in 198 aa overlap (9-205:425-602) 10 20 30 pF1KB3 MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPN :.: . . :::. ..:::. . XP_011 QHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREE-KLTDWQKLACLLCR 400 410 420 430 440 450 40 50 60 70 80 90 pF1KB3 RQRHWQTKEEATYGVWAERDSDDERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDS :: . .:: . .. : .. .. .: : : . : :.:. :. . .: XP_011 RQ--FPSKEAL---IRHQQLSGLHKQNLEIHRRAHLSE--NELEA-LEKNDMEQMKYRDR 460 470 480 490 500 100 110 120 130 140 150 pF1KB3 DDEEKPVKQDDFPKDFGPRKLKTGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQ :.. .. .:. :.. : :: .. .. : :.. .:: .::...:: XP_011 AAERR--EKYGIPEPPEPKRRKYGG-ISTASVDFEQPTRD--GLGS-----DNIGSRMLQ 510 520 530 540 550 160 170 180 190 200 210 pF1KB3 KMGYVPGRGLGKNAQGIINPIEAKQR-KGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEE ::. : :::.. :::..::::. : .:.: .:: :: . : ... XP_011 AMGWKEGSGLGRKKQGIVTPIEAQTRVRGSG-LGARGSSYGVTSTESYKETLHKTMVTRF 560 570 580 590 600 610 220 230 240 250 260 270 pF1KB3 FQKELSQWRKDPSGSKKKPKYSYKTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQK XP_011 NEAQ >>XP_016885374 (OMIM: 300080,311900) PREDICTED: RNA-bind (726 aa) initn: 177 init1: 150 opt: 183 Z-score: 172.6 bits: 42.7 E(85289): 0.0071 Smith-Waterman score: 184; 28.3% identity (56.6% similar) in 198 aa overlap (9-205:533-710) 10 20 30 pF1KB3 MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPN :.: . . :::. ..:::. . XP_016 QHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREE-KLTDWQKLACLLCR 510 520 530 540 550 560 40 50 60 70 80 90 pF1KB3 RQRHWQTKEEATYGVWAERDSDDERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDS :: . .:: . .. : .. .. .: : : . : :.:. :. . .: XP_016 RQ--FPSKEAL---IRHQQLSGLHKQNLEIHRRAHLSE--NELEA-LEKNDMEQMKYRDR 570 580 590 600 610 100 110 120 130 140 150 pF1KB3 DDEEKPVKQDDFPKDFGPRKLKTGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQ :.. .. .:. :.. : :: .. .. : :.. .:: .::...:: XP_016 AAERR--EKYGIPEPPEPKRRKYGG-ISTASVDFEQPTRD--GLGS-----DNIGSRMLQ 620 630 640 650 660 160 170 180 190 200 210 pF1KB3 KMGYVPGRGLGKNAQGIINPIEAKQR-KGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEE ::. : :::.. :::..::::. : .:.: .:: :: . : ... XP_016 AMGWKEGSGLGRKKQGIVTPIEAQTRVRGSG-LGARGSSYGVTSTESYKETLHKTMVTRF 670 680 690 700 710 720 220 230 240 250 260 270 pF1KB3 FQKELSQWRKDPSGSKKKPKYSYKTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQK XP_016 NEAQ >>XP_006724626 (OMIM: 300080,311900) PREDICTED: RNA-bind (727 aa) initn: 177 init1: 150 opt: 183 Z-score: 172.6 bits: 42.7 E(85289): 0.0071 Smith-Waterman score: 184; 28.3% identity (56.6% similar) in 198 aa overlap (9-205:534-711) 10 20 30 pF1KB3 MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPN :.: . . :::. ..:::. . XP_006 QHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREE-KLTDWQKLACLLCR 510 520 530 540 550 560 40 50 60 70 80 90 pF1KB3 RQRHWQTKEEATYGVWAERDSDDERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDS :: . .:: . .. : .. .. .: : : . : :.:. :. . .: XP_006 RQ--FPSKEAL---IRHQQLSGLHKQNLEIHRRAHLSE--NELEA-LEKNDMEQMKYRDR 570 580 590 600 610 100 110 120 130 140 150 pF1KB3 DDEEKPVKQDDFPKDFGPRKLKTGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQ :.. .. .:. :.. : :: .. .. : :.. .:: .::...:: XP_006 AAERR--EKYGIPEPPEPKRRKYGG-ISTASVDFEQPTRD--GLGS-----DNIGSRMLQ 620 630 640 650 660 160 170 180 190 200 210 pF1KB3 KMGYVPGRGLGKNAQGIINPIEAKQR-KGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEE ::. : :::.. :::..::::. : .:.: .:: :: . : ... XP_006 AMGWKEGSGLGRKKQGIVTPIEAQTRVRGSG-LGARGSSYGVTSTESYKETLHKTMVTRF 670 680 690 700 710 720 220 230 240 250 260 270 pF1KB3 FQKELSQWRKDPSGSKKKPKYSYKTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQK XP_006 NEAQ >>XP_016885373 (OMIM: 300080,311900) PREDICTED: RNA-bind (727 aa) initn: 177 init1: 150 opt: 183 Z-score: 172.6 bits: 42.7 E(85289): 0.0071 Smith-Waterman score: 184; 28.3% identity (56.6% similar) in 198 aa overlap (9-205:534-711) 10 20 30 pF1KB3 MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPN :.: . . :::. ..:::. . XP_016 QHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREE-KLTDWQKLACLLCR 510 520 530 540 550 560 40 50 60 70 80 90 pF1KB3 RQRHWQTKEEATYGVWAERDSDDERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDS :: . .:: . .. : .. .. .: : : . : :.:. :. . .: XP_016 RQ--FPSKEAL---IRHQQLSGLHKQNLEIHRRAHLSE--NELEA-LEKNDMEQMKYRDR 570 580 590 600 610 100 110 120 130 140 150 pF1KB3 DDEEKPVKQDDFPKDFGPRKLKTGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQ :.. .. .:. :.. : :: .. .. : :.. .:: .::...:: XP_016 AAERR--EKYGIPEPPEPKRRKYGG-ISTASVDFEQPTRD--GLGS-----DNIGSRMLQ 620 630 640 650 660 160 170 180 190 200 210 pF1KB3 KMGYVPGRGLGKNAQGIINPIEAKQR-KGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEE ::. : :::.. :::..::::. : .:.: .:: :: . : ... XP_016 AMGWKEGSGLGRKKQGIVTPIEAQTRVRGSG-LGARGSSYGVTSTESYKETLHKTMVTRF 670 680 690 700 710 720 220 230 240 250 260 270 pF1KB3 FQKELSQWRKDPSGSKKKPKYSYKTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQK XP_016 NEAQ >>NP_690595 (OMIM: 300080,311900) RNA-binding protein 10 (852 aa) initn: 150 init1: 150 opt: 183 Z-score: 171.7 bits: 42.8 E(85289): 0.008 Smith-Waterman score: 184; 28.3% identity (56.6% similar) in 198 aa overlap (9-205:659-836) 10 20 30 pF1KB3 MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPN :.: . . :::. ..:::. . NP_690 QHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREE-KLTDWQKLACLLCR 630 640 650 660 670 680 40 50 60 70 80 90 pF1KB3 RQRHWQTKEEATYGVWAERDSDDERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDS :: . .:: . .. : .. .. .: : : . : :.:. :. . .: NP_690 RQ--FPSKEAL---IRHQQLSGLHKQNLEIHRRAHLSE--NELEA-LEKNDMEQMKYRDR 690 700 710 720 730 100 110 120 130 140 150 pF1KB3 DDEEKPVKQDDFPKDFGPRKLKTGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQ :.. .. .:. :.. : :: .. .. : :.. .:: .::...:: NP_690 AAERR--EKYGIPEPPEPKRRKYGG-ISTASVDFEQPTRD--GLGS-----DNIGSRMLQ 740 750 760 770 780 160 170 180 190 200 210 pF1KB3 KMGYVPGRGLGKNAQGIINPIEAKQR-KGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEE ::. : :::.. :::..::::. : .:.: .:: :: . : ... NP_690 AMGWKEGSGLGRKKQGIVTPIEAQTRVRGSG-LGARGSSYGVTSTESYKETLHKTMVTRF 790 800 810 820 830 840 220 230 240 250 260 270 pF1KB3 FQKELSQWRKDPSGSKKKPKYSYKTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQK NP_690 NEAQ 850 >>NP_001191395 (OMIM: 300080,311900) RNA-binding protein (853 aa) initn: 150 init1: 150 opt: 183 Z-score: 171.7 bits: 42.8 E(85289): 0.008 Smith-Waterman score: 184; 28.3% identity (56.6% similar) in 198 aa overlap (9-205:660-837) 10 20 30 pF1KB3 MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPN :.: . . :::. ..:::. . NP_001 QHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREE-KLTDWQKLACLLCR 630 640 650 660 670 680 40 50 60 70 80 90 pF1KB3 RQRHWQTKEEATYGVWAERDSDDERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDS :: . .:: . .. : .. .. .: : : . : :.:. :. . .: NP_001 RQ--FPSKEAL---IRHQQLSGLHKQNLEIHRRAHLSE--NELEA-LEKNDMEQMKYRDR 690 700 710 720 730 740 100 110 120 130 140 150 pF1KB3 DDEEKPVKQDDFPKDFGPRKLKTGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQ :.. .. .:. :.. : :: .. .. : :.. .:: .::...:: NP_001 AAERR--EKYGIPEPPEPKRRKYGG-ISTASVDFEQPTRD--GLGS-----DNIGSRMLQ 750 760 770 780 790 160 170 180 190 200 210 pF1KB3 KMGYVPGRGLGKNAQGIINPIEAKQR-KGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEE ::. : :::.. :::..::::. : .:.: .:: :: . : ... NP_001 AMGWKEGSGLGRKKQGIVTPIEAQTRVRGSG-LGARGSSYGVTSTESYKETLHKTMVTRF 800 810 820 830 840 220 230 240 250 260 270 pF1KB3 FQKELSQWRKDPSGSKKKPKYSYKTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQK NP_001 NEAQ 850 837 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:26:48 2016 done: Thu Nov 3 12:26:50 2016 Total Scan time: 12.940 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]