FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3107, 165 aa 1>>>pF1KB3107 165 - 165 aa - 165 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7607+/-0.000614; mu= 10.9052+/- 0.037 mean_var=97.5003+/-20.013, 0's: 0 Z-trim(114.7): 120 B-trim: 0 in 0/51 Lambda= 0.129889 statistics sampled from 15083 (15224) to 15083 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.468), width: 16 Scan time: 1.800 The best scores are: opt bits E(32554) CCDS713.1 LMO4 gene_id:8543|Hs108|chr1 ( 165) 1202 234.3 2.5e-62 CCDS58118.1 LMO1 gene_id:4004|Hs108|chr11 ( 155) 554 112.9 8.6e-26 CCDS44534.1 LMO1 gene_id:4004|Hs108|chr11 ( 156) 554 112.9 8.6e-26 CCDS8678.1 LMO3 gene_id:55885|Hs108|chr12 ( 145) 539 110.1 5.7e-25 CCDS58211.1 LMO3 gene_id:55885|Hs108|chr12 ( 156) 539 110.1 6.1e-25 CCDS58212.1 LMO3 gene_id:55885|Hs108|chr12 ( 163) 539 110.1 6.3e-25 CCDS44567.1 LMO2 gene_id:4005|Hs108|chr11 ( 158) 451 93.6 5.6e-20 CCDS7888.2 LMO2 gene_id:4005|Hs108|chr11 ( 227) 451 93.7 7.4e-20 CCDS1338.1 LHX4 gene_id:89884|Hs108|chr1 ( 390) 427 89.4 2.5e-18 CCDS30962.1 LHX9 gene_id:56956|Hs108|chr1 ( 388) 426 89.2 2.8e-18 CCDS1393.1 LHX9 gene_id:56956|Hs108|chr1 ( 397) 426 89.3 2.9e-18 CCDS6853.1 LHX2 gene_id:9355|Hs108|chr9 ( 406) 417 87.6 9.5e-18 CCDS6994.1 LHX3 gene_id:8022|Hs108|chr9 ( 397) 405 85.3 4.4e-17 CCDS6995.1 LHX3 gene_id:8022|Hs108|chr9 ( 402) 405 85.3 4.5e-17 CCDS10290.1 ISL2 gene_id:64843|Hs108|chr15 ( 359) 395 83.4 1.5e-16 CCDS9171.1 LHX5 gene_id:64211|Hs108|chr12 ( 402) 388 82.1 4.1e-16 CCDS58008.1 LHX8 gene_id:431707|Hs108|chr1 ( 346) 387 81.9 4.1e-16 CCDS30756.1 LHX8 gene_id:431707|Hs108|chr1 ( 356) 387 81.9 4.2e-16 CCDS56583.1 LHX6 gene_id:26468|Hs108|chr9 ( 363) 382 81.0 8.2e-16 CCDS56584.1 LHX6 gene_id:26468|Hs108|chr9 ( 366) 382 81.0 8.3e-16 CCDS6837.2 LHX6 gene_id:26468|Hs108|chr9 ( 377) 382 81.0 8.4e-16 CCDS6838.2 LHX6 gene_id:26468|Hs108|chr9 ( 392) 382 81.0 8.7e-16 CCDS11316.1 LHX1 gene_id:3975|Hs108|chr17 ( 406) 380 80.6 1.2e-15 CCDS43314.1 ISL1 gene_id:3670|Hs108|chr5 ( 349) 376 79.8 1.7e-15 CCDS6866.2 LMX1B gene_id:4010|Hs108|chr9 ( 395) 369 78.6 4.7e-15 CCDS55342.1 LMX1B gene_id:4010|Hs108|chr9 ( 402) 369 78.6 4.8e-15 CCDS55343.1 LMX1B gene_id:4010|Hs108|chr9 ( 406) 369 78.6 4.8e-15 CCDS1247.1 LMX1A gene_id:4009|Hs108|chr1 ( 382) 363 77.4 1e-14 >>CCDS713.1 LMO4 gene_id:8543|Hs108|chr1 (165 aa) initn: 1202 init1: 1202 opt: 1202 Z-score: 1232.4 bits: 234.3 E(32554): 2.5e-62 Smith-Waterman score: 1202; 100.0% identity (100.0% similar) in 165 aa overlap (1-165:1-165) 10 20 30 40 50 60 pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN 70 80 90 100 110 120 130 140 150 160 pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC ::::::::::::::::::::::::::::::::::::::::::::: CCDS71 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC 130 140 150 160 >>CCDS58118.1 LMO1 gene_id:4004|Hs108|chr11 (155 aa) initn: 638 init1: 554 opt: 554 Z-score: 576.5 bits: 112.9 E(32554): 8.6e-26 Smith-Waterman score: 554; 52.3% identity (78.8% similar) in 132 aa overlap (21-152:21-152) 10 20 30 40 50 60 pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI : ::::. :: ::.:: :.:.::: ::::.::. .::.. CCDS58 MVLDQEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN :.. :::...:::: ::.::::..: :.::.. ::: :.::::. ::::: ::.:. : . CCDS58 GSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQ 70 80 90 100 110 120 130 140 150 160 pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC :. ::.: :. ..:. : . .:: ..: CCDS58 RFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ 130 140 150 >>CCDS44534.1 LMO1 gene_id:4004|Hs108|chr11 (156 aa) initn: 638 init1: 554 opt: 554 Z-score: 576.5 bits: 112.9 E(32554): 8.6e-26 Smith-Waterman score: 554; 52.3% identity (78.8% similar) in 132 aa overlap (21-152:22-153) 10 20 30 40 50 pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGD : ::::. :: ::.:: :.:.::: ::::.::. .::. CCDS44 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 IGTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCR .:.. :::...:::: ::.::::..: :.::.. ::: :.::::. ::::: ::.:. : CCDS44 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN 70 80 90 100 110 120 120 130 140 150 160 pF1KB3 NRLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC .:. ::.: :. ..:. : . .:: ..: CCDS44 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ 130 140 150 >>CCDS8678.1 LMO3 gene_id:55885|Hs108|chr12 (145 aa) initn: 546 init1: 508 opt: 539 Z-score: 561.7 bits: 110.1 E(32554): 5.7e-25 Smith-Waterman score: 539; 53.2% identity (78.6% similar) in 126 aa overlap (21-146:11-136) 10 20 30 40 50 60 pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI : ::::. :: ::.:: :.:.::: ::::.::. .::.. CCDS86 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN :.. :::...:::: ::.:::: .: :.::.. ::: :.::::. ::::: ::.:. : . CCDS86 GSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQ 60 70 80 90 100 110 130 140 150 160 pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC :. ::.: :. ..:. : .:. CCDS86 RFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR 120 130 140 >>CCDS58211.1 LMO3 gene_id:55885|Hs108|chr12 (156 aa) initn: 546 init1: 508 opt: 539 Z-score: 561.3 bits: 110.1 E(32554): 6.1e-25 Smith-Waterman score: 539; 53.2% identity (78.6% similar) in 126 aa overlap (21-146:22-147) 10 20 30 40 50 pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGD : ::::. :: ::.:: :.:.::: ::::.::. .::. CCDS58 MQKKEKSFGIQMLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 IGTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCR .:.. :::...:::: ::.:::: .: :.::.. ::: :.::::. ::::: ::.:. : CCDS58 VGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCN 70 80 90 100 110 120 120 130 140 150 160 pF1KB3 NRLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC .:. ::.: :. ..:. : .:. CCDS58 QRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR 130 140 150 >>CCDS58212.1 LMO3 gene_id:55885|Hs108|chr12 (163 aa) initn: 549 init1: 511 opt: 539 Z-score: 561.0 bits: 110.1 E(32554): 6.3e-25 Smith-Waterman score: 539; 53.2% identity (78.6% similar) in 126 aa overlap (21-146:29-154) 10 20 30 40 50 pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSC : ::::. :: ::.:: :.:.::: ::::.: CCDS58 MLMEGGRAAAARNVSSIQMLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCAC 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 CQAQLGDIGTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKC :. .::..:.. :::...:::: ::.:::: .: :.::.. ::: :.::::. ::::: : CCDS58 CDCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDC 70 80 90 100 110 120 120 130 140 150 160 pF1KB3 FTCSTCRNRLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC :.:. : .:. ::.: :. ..:. : .:. CCDS58 FACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR 130 140 150 160 >>CCDS44567.1 LMO2 gene_id:4005|Hs108|chr11 (158 aa) initn: 486 init1: 436 opt: 451 Z-score: 472.1 bits: 93.6 E(32554): 5.6e-20 Smith-Waterman score: 451; 43.4% identity (69.2% similar) in 143 aa overlap (9-150:22-158) 10 20 30 40 pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRC : :: : :.:: .:.::..: :.:.::: : CCDS44 MSSAIERKSLDPSEEPVDEVLQIPP------SLLTCGGCQQNIGDRYFLKAIDQYWHEDC 10 20 30 40 50 50 60 70 80 90 100 pF1KB3 LKCSCCQAQLGDIGTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNV :.:. : .::..: : : : ::: ::.::::..: :..: . : : :..::.. .: CCDS44 LSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKV 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB3 YHLKCFTCSTCRNRLVPGDRFHYINGSLFCEHD-RPTALINGHLNSLQSNPLLPDQKVC :::.:: :..:.... :::. ::... ::.: . ::: . CCDS44 YHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI 120 130 140 150 >>CCDS7888.2 LMO2 gene_id:4005|Hs108|chr11 (227 aa) initn: 511 init1: 436 opt: 451 Z-score: 470.0 bits: 93.7 E(32554): 7.4e-20 Smith-Waterman score: 451; 43.4% identity (69.2% similar) in 143 aa overlap (9-150:91-227) 10 20 30 pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYA : :: : :.:: .:.::..: : CCDS78 PPGTPPPSPMSSAIERKSLDPSEEPVDEVLQIPP------SLLTCGGCQQNIGDRYFLKA 70 80 90 100 110 40 50 60 70 80 90 pF1KB3 MDSYWHSRCLKCSCCQAQLGDIGTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASE .:.::: ::.:. : .::..: : : : ::: ::.::::..: :..: . : : : CCDS78 IDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYE 120 130 140 150 160 170 100 110 120 130 140 150 pF1KB3 LVMRAQGNVYHLKCFTCSTCRNRLVPGDRFHYINGSLFCEHD-RPTALINGHLNSLQSNP ..::.. .::::.:: :..:.... :::. ::... ::.: . ::: . CCDS78 MTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI 180 190 200 210 220 160 pF1KB3 LLPDQKVC >>CCDS1338.1 LHX4 gene_id:89884|Hs108|chr1 (390 aa) initn: 335 init1: 178 opt: 427 Z-score: 442.5 bits: 89.4 E(32554): 2.5e-18 Smith-Waterman score: 427; 43.3% identity (73.2% similar) in 127 aa overlap (22-147:29-150) 10 20 30 40 50 pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCC .::::. .: :.:.: ..: .::: ::::. : CCDS13 MMQSATVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADC 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 QAQLGDIGTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCF : ::.: :....: . :..:... ::.. :.:: :.:: ...: .:: ::::.:: CCDS13 QMQLAD---RCFSRAGSVYCKEDFFKRFGTK--CTACQQGIPPTQVVRKAQDFVYHLHCF 70 80 90 100 110 120 130 140 150 160 pF1KB3 TCSTCRNRLVPGDRFHYI-NGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC .: : .:. ::.:. . .: : :..: :: : CCDS13 ACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNA 120 130 140 150 160 170 CCDS13 YKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSR 180 190 200 210 220 230 >>CCDS30962.1 LHX9 gene_id:56956|Hs108|chr1 (388 aa) initn: 426 init1: 185 opt: 426 Z-score: 441.5 bits: 89.2 E(32554): 2.8e-18 Smith-Waterman score: 426; 44.0% identity (68.1% similar) in 141 aa overlap (5-145:46-182) 10 20 30 pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRF : .. ::.. . . ::::::::.::. CCDS30 ISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKPAL--CAGCGGKISDRY 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB3 LLYAMDSYWHSRCLKCSCCQAQLGDIGTSCYTKSGMILCRNDYIRLFGNSGACSACGQSI : :.:. :: ::::: :. : . .:..:.: : :..:: : : . :. : .: CCDS30 YLLAVDKQWHLRCLKCCECKLAL-ESELTCFAKDGSIYCKEDYYRRF-SVQRCARCHLGI 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB3 PASELVMRAQGNVYHLKCFTCSTCRNRLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQ :::.::::. .::::.::::::: . :. ::.: . .. ..:. : : CCDS30 SASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLS 140 150 160 170 180 190 160 pF1KB3 SNPLLPDQKVC CCDS30 YTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQP 200 210 220 230 240 250 165 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:27:22 2016 done: Thu Nov 3 12:27:23 2016 Total Scan time: 1.800 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]