FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3111, 361 aa 1>>>pF1KB3111 361 - 361 aa - 361 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4657+/-0.000398; mu= 6.0540+/- 0.025 mean_var=125.2810+/-26.436, 0's: 0 Z-trim(115.3): 99 B-trim: 1348 in 1/55 Lambda= 0.114586 statistics sampled from 25453 (25592) to 25453 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.3), width: 16 Scan time: 8.690 The best scores are: opt bits E(85289) NP_001122384 (OMIM: 601210) poly(rC)-binding prote ( 361) 2352 400.1 4e-111 NP_114366 (OMIM: 601210) poly(rC)-binding protein ( 362) 2340 398.1 1.6e-110 NP_001122383 (OMIM: 601210) poly(rC)-binding prote ( 365) 2334 397.1 3.2e-110 NP_005007 (OMIM: 601210) poly(rC)-binding protein ( 366) 2322 395.2 1.3e-109 NP_006187 (OMIM: 601209) poly(rC)-binding protein ( 356) 1864 319.4 7.6e-87 NP_001122386 (OMIM: 601210) poly(rC)-binding prote ( 318) 1246 217.2 3.9e-56 NP_001092090 (OMIM: 601210) poly(rC)-binding prote ( 331) 1246 217.3 4.1e-56 NP_001122385 (OMIM: 601210) poly(rC)-binding prote ( 335) 1228 214.3 3.2e-55 NP_065389 (OMIM: 608502) poly(rC)-binding protein ( 371) 1101 193.3 7.4e-49 NP_001123613 (OMIM: 608502) poly(rC)-binding prote ( 345) 932 165.4 1.8e-40 XP_016862406 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 323) 855 152.6 1.1e-36 XP_016862407 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 323) 855 152.6 1.1e-36 XP_016862408 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 323) 855 152.6 1.1e-36 XP_006713334 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 346) 855 152.6 1.2e-36 NP_127501 (OMIM: 608503) poly(rC)-binding protein ( 403) 855 152.7 1.4e-36 XP_006713332 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 403) 855 152.7 1.4e-36 XP_005265388 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 403) 855 152.7 1.4e-36 NP_001167571 (OMIM: 608503) poly(rC)-binding prote ( 403) 855 152.7 1.4e-36 XP_006713331 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 403) 855 152.7 1.4e-36 NP_127503 (OMIM: 608503) poly(rC)-binding protein ( 403) 855 152.7 1.4e-36 XP_016862405 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 426) 855 152.7 1.4e-36 XP_005265387 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 426) 855 152.7 1.4e-36 XP_016862409 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 280) 538 100.2 6e-21 XP_006713333 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 360) 538 100.2 7.5e-21 NP_065151 (OMIM: 608503) poly(rC)-binding protein ( 360) 538 100.2 7.5e-21 XP_005265389 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 383) 538 100.2 7.9e-21 XP_011516918 (OMIM: 600712,616580) PREDICTED: hete ( 439) 345 68.4 3.6e-11 NP_001305115 (OMIM: 600712,616580) heterogeneous n ( 439) 345 68.4 3.6e-11 XP_016870158 (OMIM: 600712,616580) PREDICTED: hete ( 439) 345 68.4 3.6e-11 XP_005252022 (OMIM: 600712,616580) PREDICTED: hete ( 440) 345 68.4 3.6e-11 XP_005252020 (OMIM: 600712,616580) PREDICTED: hete ( 440) 345 68.4 3.6e-11 NP_001305116 (OMIM: 600712,616580) heterogeneous n ( 440) 345 68.4 3.6e-11 XP_006713541 (OMIM: 125853,608289) PREDICTED: insu ( 300) 246 51.9 2.2e-06 XP_006713540 (OMIM: 125853,608289) PREDICTED: insu ( 343) 246 51.9 2.4e-06 NP_001153895 (OMIM: 608288) insulin-like growth fa ( 438) 230 49.4 1.9e-05 XP_016870157 (OMIM: 600712,616580) PREDICTED: hete ( 463) 224 48.4 3.9e-05 NP_001305117 (OMIM: 600712,616580) heterogeneous n ( 463) 224 48.4 3.9e-05 NP_112552 (OMIM: 600712,616580) heterogeneous nucl ( 463) 224 48.4 3.9e-05 NP_002131 (OMIM: 600712,616580) heterogeneous nucl ( 464) 224 48.4 3.9e-05 NP_112553 (OMIM: 600712,616580) heterogeneous nucl ( 464) 224 48.4 3.9e-05 XP_005252017 (OMIM: 600712,616580) PREDICTED: hete ( 464) 224 48.4 3.9e-05 XP_016870761 (OMIM: 603536) PREDICTED: far upstrea ( 377) 214 46.7 0.0001 XP_016870760 (OMIM: 603536) PREDICTED: far upstrea ( 377) 214 46.7 0.0001 XP_016870759 (OMIM: 603536) PREDICTED: far upstrea ( 377) 214 46.7 0.0001 XP_006717376 (OMIM: 603536) PREDICTED: far upstrea ( 485) 214 46.7 0.00013 XP_011517476 (OMIM: 603536) PREDICTED: far upstrea ( 485) 214 46.7 0.00013 NP_001278803 (OMIM: 125853,608289) insulin-like gr ( 493) 214 46.7 0.00013 XP_011517475 (OMIM: 603536) PREDICTED: far upstrea ( 499) 214 46.7 0.00013 NP_001007226 (OMIM: 125853,608289) insulin-like gr ( 556) 214 46.8 0.00014 XP_016861047 (OMIM: 125853,608289) PREDICTED: insu ( 562) 214 46.8 0.00015 >>NP_001122384 (OMIM: 601210) poly(rC)-binding protein 2 (361 aa) initn: 2352 init1: 2352 opt: 2352 Z-score: 2116.0 bits: 400.1 E(85289): 4e-111 Smith-Waterman score: 2352; 100.0% identity (100.0% similar) in 361 aa overlap (1-361:1-361) 10 20 30 40 50 60 pF1KB3 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 RQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS 310 320 330 340 350 360 pF1KB3 S : NP_001 S >>NP_114366 (OMIM: 601210) poly(rC)-binding protein 2 is (362 aa) initn: 2338 init1: 1819 opt: 2340 Z-score: 2105.3 bits: 398.1 E(85289): 1.6e-110 Smith-Waterman score: 2340; 99.7% identity (99.7% similar) in 362 aa overlap (1-361:1-362) 10 20 30 40 50 60 pF1KB3 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW-GLDASAQTTSHELTIPNDLIGCII ::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::: NP_114 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 310 320 330 340 350 360 360 pF1KB3 SS :: NP_114 SS >>NP_001122383 (OMIM: 601210) poly(rC)-binding protein 2 (365 aa) initn: 1288 init1: 1288 opt: 2334 Z-score: 2099.9 bits: 397.1 E(85289): 3.2e-110 Smith-Waterman score: 2334; 98.9% identity (98.9% similar) in 365 aa overlap (1-361:1-365) 10 20 30 40 50 60 pF1KB3 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI :::::::::::::::::::::::::::::::::::::::::::::::: :::::::: NP_001 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIG 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG 310 320 330 340 350 360 360 pF1KB3 GMGSS ::::: NP_001 GMGSS >>NP_005007 (OMIM: 601210) poly(rC)-binding protein 2 is (366 aa) initn: 1733 init1: 1068 opt: 2322 Z-score: 2089.1 bits: 395.2 E(85289): 1.3e-109 Smith-Waterman score: 2322; 98.6% identity (98.6% similar) in 366 aa overlap (1-361:1-366) 10 20 30 40 50 60 pF1KB3 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI :::::::::::::::::::::::::::::::::::::::::::::::: :::::::: NP_005 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW-GLDASAQTTSHELTIPNDLI ::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::: NP_005 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 310 320 330 340 350 360 360 pF1KB3 GGMGSS :::::: NP_005 GGMGSS >>NP_006187 (OMIM: 601209) poly(rC)-binding protein 1 [H (356 aa) initn: 1846 init1: 1017 opt: 1864 Z-score: 1680.1 bits: 319.4 E(85289): 7.6e-87 Smith-Waterman score: 1864; 81.5% identity (91.0% similar) in 367 aa overlap (1-361:1-356) 10 20 30 40 50 60 pF1KB3 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT ::.:: :.:::::::::::::::::::::::::::::..::::::::::::::::::::: NP_006 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI :.:::::::::::::::::::::.::::::::::::::::::::::.::::::::::::: NP_006 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLES---PPKG--VT ::::::::::::::::::::::::::::::.:::. :::::::.::::. :.: .: NP_006 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 IPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIP :::.: :.::::: :::::: ::.:..::.: :::::::.::.::::..: NP_006 IPYQPMPASSPVICAGGQDRC---SDAAGYPHATH------DLEGPPLDAYSIQGQHTIS 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 QPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWG-LDASAQTTSHELTIPNDL ::.::.:.: ::::: : ::.:::.::.::::::::::. ::::.::: :::::::.: NP_006 PLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 IGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSE ::::::::::.:::::::::::::::::::::. ::::::::::::::::::::.::::: NP_006 IGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSE 300 310 320 330 340 350 360 pF1KB3 TGGMGSS : :: : NP_006 KG-MGCS >>NP_001122386 (OMIM: 601210) poly(rC)-binding protein 2 (318 aa) initn: 1765 init1: 1246 opt: 1246 Z-score: 1128.7 bits: 217.2 E(85289): 3.9e-56 Smith-Waterman score: 1932; 87.8% identity (88.1% similar) in 361 aa overlap (1-361:1-318) 10 20 30 40 50 60 pF1KB3 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT ::::::::::::: :::::::::::::::: NP_001 KPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQPDLT 190 200 250 260 270 280 290 300 pF1KB3 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIG ::::::::::::::::::::::. ::::::::::::::::::::::::: NP_001 KLHQLAMQQSHFPMTHGNTGFSA------------GLDASAQTTSHELTIPNDLIGCIIG 210 220 230 240 250 310 320 330 340 350 360 pF1KB3 RQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS 260 270 280 290 300 310 pF1KB3 S : NP_001 S >>NP_001092090 (OMIM: 601210) poly(rC)-binding protein 2 (331 aa) initn: 1761 init1: 1242 opt: 1246 Z-score: 1128.5 bits: 217.3 E(85289): 4.1e-56 Smith-Waterman score: 2046; 91.2% identity (91.2% similar) in 362 aa overlap (1-361:1-331) 10 20 30 40 50 60 pF1KB3 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT ::::::::::::: :::::::::::::::: NP_001 KPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQPDLT 190 200 250 260 270 280 290 pF1KB3 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW-GLDASAQTTSHELTIPNDLIGCII ::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::: NP_001 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB3 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 270 280 290 300 310 320 360 pF1KB3 SS :: NP_001 SS 330 >>NP_001122385 (OMIM: 601210) poly(rC)-binding protein 2 (335 aa) initn: 2054 init1: 1068 opt: 1228 Z-score: 1112.3 bits: 214.3 E(85289): 3.2e-55 Smith-Waterman score: 2028; 90.2% identity (90.2% similar) in 366 aa overlap (1-361:1-335) 10 20 30 40 50 60 pF1KB3 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI :::::::::::::::::::::::::::::::::::::::::::::::: :::::::: NP_001 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ ::::::::::::::::: :::::::::::: NP_001 PYRPKPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQ 190 200 240 250 260 270 280 290 pF1KB3 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW-GLDASAQTTSHELTIPNDLI ::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::: NP_001 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB3 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 270 280 290 300 310 320 360 pF1KB3 GGMGSS :::::: NP_001 GGMGSS 330 >>NP_065389 (OMIM: 608502) poly(rC)-binding protein 3 is (371 aa) initn: 1591 init1: 1099 opt: 1101 Z-score: 998.2 bits: 193.3 E(85289): 7.4e-49 Smith-Waterman score: 1609; 71.3% identity (82.9% similar) in 369 aa overlap (1-360:33-370) 10 20 30 pF1KB3 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIG :.. : :::::::::::::::::::::::: NP_065 EGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB3 KKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNS ::::.:::::::::::::::::::::::.:..:::.::::::::: :.:::: .::.:: NP_065 KKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNS 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB3 TAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG :.:.:::::::::::::::::::::: :::::::::::::::::::::::::::.::.: NP_065 PATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISG 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB3 IPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTP :..::.::::::::::::::::.::::::::.:.:::::::: NP_065 TPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQ----------------- 190 200 210 220 220 230 240 250 260 pF1KB3 SMCLNPDLEGPPLEAYTIQGQYAIPQPD-LTKLHQLAMQQSHFP-MTHGNTGFSGIE--- :::::::::::.:: :::::::::::. :: . . : .: : . NP_065 --------------AYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPL 230 240 250 260 270 270 280 290 300 310 320 pF1KB3 SSSPEVKGYWG----LDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIAN :: :... : :::: ...::::::::::::::::::.::::::::::::::::: NP_065 HSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIAN 280 290 300 310 320 330 330 340 350 360 pF1KB3 PVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS .:::..::.::::. :.:::::::::.::.::. :::. NP_065 ATEGSSERQITITGTPANISLAQYLINARLTSEVTGMGTL 340 350 360 370 >>NP_001123613 (OMIM: 608502) poly(rC)-binding protein 3 (345 aa) initn: 1428 init1: 921 opt: 932 Z-score: 847.7 bits: 165.4 E(85289): 1.8e-40 Smith-Waterman score: 1407; 65.5% identity (76.4% similar) in 368 aa overlap (1-360:33-344) 10 20 30 pF1KB3 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIG :.. : :::::::::::::::::::::::: NP_001 EGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB3 KKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNS ::::.:::::::::::::::::::::::.:..:::.::::::::: :.:::: .::.:: NP_001 KKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNS 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB3 TAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG :.:.:::::::::::::::::::::: :::::::::::::::::::::::::::.::.: NP_001 PATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISG 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB3 IPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTP :..::.::::::::::: NP_001 TPDAIIQCVKQICVVMLE------------------------------------------ 190 200 220 230 240 250 260 pF1KB3 SMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFP-MTHGNTGFSGIE---S :::::::::::.:::::::::::::. :: . . : .: : . NP_001 --------------AYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLH 210 220 230 240 270 280 290 300 310 320 pF1KB3 SSPEVKGYWG----LDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP :: :... : :::: ...::::::::::::::::::.::::::::::::::::: NP_001 SSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANA 250 260 270 280 290 300 330 340 350 360 pF1KB3 VEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS .:::..::.::::. :.:::::::::.::.::. :::. NP_001 TEGSSERQITITGTPANISLAQYLINARLTSEVTGMGTL 310 320 330 340 361 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:11:01 2016 done: Fri Nov 4 02:11:03 2016 Total Scan time: 8.690 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]