FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3115, 423 aa 1>>>pF1KB3115 423 - 423 aa - 423 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9228+/-0.000455; mu= 20.2431+/- 0.028 mean_var=68.4159+/-14.219, 0's: 0 Z-trim(108.6): 44 B-trim: 195 in 1/53 Lambda= 0.155059 statistics sampled from 16624 (16651) to 16624 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.546), E-opt: 0.2 (0.195), width: 16 Scan time: 8.270 The best scores are: opt bits E(85289) NP_003644 (OMIM: 604665) COP9 signalosome complex ( 423) 2771 629.3 5.5e-180 NP_001186054 (OMIM: 604665) COP9 signalosome compl ( 403) 2650 602.2 7.4e-172 XP_005256894 (OMIM: 604665) PREDICTED: COP9 signal ( 403) 2650 602.2 7.4e-172 NP_001303285 (OMIM: 604665) COP9 signalosome compl ( 356) 2360 537.3 2.3e-152 NP_001303287 (OMIM: 604665) COP9 signalosome compl ( 318) 2031 463.7 3e-130 NP_001303286 (OMIM: 604665) COP9 signalosome compl ( 318) 2031 463.7 3e-130 XP_016880735 (OMIM: 604665) PREDICTED: COP9 signal ( 318) 2031 463.7 3e-130 XP_005256897 (OMIM: 604665) PREDICTED: COP9 signal ( 293) 1940 443.3 3.8e-124 XP_005256899 (OMIM: 604665) PREDICTED: COP9 signal ( 293) 1940 443.3 3.8e-124 NP_001303283 (OMIM: 604665) COP9 signalosome compl ( 293) 1940 443.3 3.8e-124 NP_001303284 (OMIM: 604665) COP9 signalosome compl ( 365) 1679 385.0 1.7e-106 >>NP_003644 (OMIM: 604665) COP9 signalosome complex subu (423 aa) initn: 2771 init1: 2771 opt: 2771 Z-score: 3352.4 bits: 629.3 E(85289): 5.5e-180 Smith-Waterman score: 2771; 100.0% identity (100.0% similar) in 423 aa overlap (1-423:1-423) 10 20 30 40 50 60 pF1KB3 MASALEQFVNSVRQLSAQGQMTQLCELINKSGELLAKNLSHLDTVLGALDVQEHSLGVLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MASALEQFVNSVRQLSAQGQMTQLCELINKSGELLAKNLSHLDTVLGALDVQEHSLGVLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 VLFVKFSMPSVPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VLFVKFSMPSVPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 IGILKQAIDKMQMNTNQLTSIHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 IGILKQAIDKMQMNTNQLTSIHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 FLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 HDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 HDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPS 370 380 390 400 410 420 pF1KB3 SYS ::: NP_003 SYS >>NP_001186054 (OMIM: 604665) COP9 signalosome complex s (403 aa) initn: 2650 init1: 2650 opt: 2650 Z-score: 3206.4 bits: 602.2 E(85289): 7.4e-172 Smith-Waterman score: 2650; 100.0% identity (100.0% similar) in 403 aa overlap (21-423:1-403) 10 20 30 40 50 60 pF1KB3 MASALEQFVNSVRQLSAQGQMTQLCELINKSGELLAKNLSHLDTVLGALDVQEHSLGVLA :::::::::::::::::::::::::::::::::::::::: NP_001 MTQLCELINKSGELLAKNLSHLDTVLGALDVQEHSLGVLA 10 20 30 40 70 80 90 100 110 120 pF1KB3 VLFVKFSMPSVPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLFVKFSMPSVPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB3 IGILKQAIDKMQMNTNQLTSIHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGILKQAIDKMQMNTNQLTSIHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKH 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 FLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQ 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 LPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLS 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 SLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSF 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 HDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPS 350 360 370 380 390 400 pF1KB3 SYS ::: NP_001 SYS >>XP_005256894 (OMIM: 604665) PREDICTED: COP9 signalosom (403 aa) initn: 2650 init1: 2650 opt: 2650 Z-score: 3206.4 bits: 602.2 E(85289): 7.4e-172 Smith-Waterman score: 2650; 100.0% identity (100.0% similar) in 403 aa overlap (21-423:1-403) 10 20 30 40 50 60 pF1KB3 MASALEQFVNSVRQLSAQGQMTQLCELINKSGELLAKNLSHLDTVLGALDVQEHSLGVLA :::::::::::::::::::::::::::::::::::::::: XP_005 MTQLCELINKSGELLAKNLSHLDTVLGALDVQEHSLGVLA 10 20 30 40 70 80 90 100 110 120 pF1KB3 VLFVKFSMPSVPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLFVKFSMPSVPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB3 IGILKQAIDKMQMNTNQLTSIHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IGILKQAIDKMQMNTNQLTSIHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKH 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 FLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQ 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 LPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLS 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 SLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSF 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 HDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPS 350 360 370 380 390 400 pF1KB3 SYS ::: XP_005 SYS >>NP_001303285 (OMIM: 604665) COP9 signalosome complex s (356 aa) initn: 2360 init1: 2360 opt: 2360 Z-score: 2856.5 bits: 537.3 E(85289): 2.3e-152 Smith-Waterman score: 2360; 100.0% identity (100.0% similar) in 356 aa overlap (68-423:1-356) 40 50 60 70 80 90 pF1KB3 NLSHLDTVLGALDVQEHSLGVLAVLFVKFSMPSVPDFETLFSQVQLFISTCNGEHIRYAT :::::::::::::::::::::::::::::: NP_001 MPSVPDFETLFSQVQLFISTCNGEHIRYAT 10 20 30 100 110 120 130 140 150 pF1KB3 DTFAGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSIHADLCQLCLLAKCFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTFAGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSIHADLCQLCLLAKCFKP 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB3 ALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVS 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB3 HIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRN 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB3 LVNKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVNKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKY 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB3 VLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEI 280 290 300 310 320 330 400 410 420 pF1KB3 TVNPQFVQKSMGSQEDDSGNKPSSYS :::::::::::::::::::::::::: NP_001 TVNPQFVQKSMGSQEDDSGNKPSSYS 340 350 >>NP_001303287 (OMIM: 604665) COP9 signalosome complex s (318 aa) initn: 2031 init1: 2031 opt: 2031 Z-score: 2459.4 bits: 463.7 E(85289): 3e-130 Smith-Waterman score: 2031; 98.4% identity (99.4% similar) in 312 aa overlap (112-423:7-318) 90 100 110 120 130 140 pF1KB3 QLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSI ... ::::::::::::::::::::::::: NP_001 MGSTFDMQQTLPLRGIGILKQAIDKMQMNTNQLTSI 10 20 30 150 160 170 180 190 200 pF1KB3 HADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERA 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB3 LYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYH 100 110 120 130 140 150 270 280 290 300 310 320 pF1KB3 ELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQD 160 170 180 190 200 210 330 340 350 360 370 380 pF1KB3 MASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEML 220 230 240 250 260 270 390 400 410 420 pF1KB3 KCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPSSYS :::::::::::::::::::::::::::::::::::::::::: NP_001 KCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPSSYS 280 290 300 310 >>NP_001303286 (OMIM: 604665) COP9 signalosome complex s (318 aa) initn: 2031 init1: 2031 opt: 2031 Z-score: 2459.4 bits: 463.7 E(85289): 3e-130 Smith-Waterman score: 2031; 98.4% identity (99.4% similar) in 312 aa overlap (112-423:7-318) 90 100 110 120 130 140 pF1KB3 QLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSI ... ::::::::::::::::::::::::: NP_001 MGSTFDMQQTLPLRGIGILKQAIDKMQMNTNQLTSI 10 20 30 150 160 170 180 190 200 pF1KB3 HADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERA 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB3 LYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYH 100 110 120 130 140 150 270 280 290 300 310 320 pF1KB3 ELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQD 160 170 180 190 200 210 330 340 350 360 370 380 pF1KB3 MASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEML 220 230 240 250 260 270 390 400 410 420 pF1KB3 KCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPSSYS :::::::::::::::::::::::::::::::::::::::::: NP_001 KCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPSSYS 280 290 300 310 >>XP_016880735 (OMIM: 604665) PREDICTED: COP9 signalosom (318 aa) initn: 2031 init1: 2031 opt: 2031 Z-score: 2459.4 bits: 463.7 E(85289): 3e-130 Smith-Waterman score: 2031; 98.4% identity (99.4% similar) in 312 aa overlap (112-423:7-318) 90 100 110 120 130 140 pF1KB3 QLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSI ... ::::::::::::::::::::::::: XP_016 MGSTFDMQQTLPLRGIGILKQAIDKMQMNTNQLTSI 10 20 30 150 160 170 180 190 200 pF1KB3 HADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERA 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB3 LYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYH 100 110 120 130 140 150 270 280 290 300 310 320 pF1KB3 ELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQD 160 170 180 190 200 210 330 340 350 360 370 380 pF1KB3 MASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEML 220 230 240 250 260 270 390 400 410 420 pF1KB3 KCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPSSYS :::::::::::::::::::::::::::::::::::::::::: XP_016 KCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPSSYS 280 290 300 310 >>XP_005256897 (OMIM: 604665) PREDICTED: COP9 signalosom (293 aa) initn: 1940 init1: 1940 opt: 1940 Z-score: 2349.9 bits: 443.3 E(85289): 3.8e-124 Smith-Waterman score: 1940; 100.0% identity (100.0% similar) in 293 aa overlap (131-423:1-293) 110 120 130 140 150 160 pF1KB3 AGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSIHADLCQLCLLAKCFKPALP :::::::::::::::::::::::::::::: XP_005 MQMNTNQLTSIHADLCQLCLLAKCFKPALP 10 20 30 170 180 190 200 210 220 pF1KB3 YLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIM 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB3 LESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVN 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB3 KHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLH 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB3 MIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVN 220 230 240 250 260 270 410 420 pF1KB3 PQFVQKSMGSQEDDSGNKPSSYS ::::::::::::::::::::::: XP_005 PQFVQKSMGSQEDDSGNKPSSYS 280 290 >>XP_005256899 (OMIM: 604665) PREDICTED: COP9 signalosom (293 aa) initn: 1940 init1: 1940 opt: 1940 Z-score: 2349.9 bits: 443.3 E(85289): 3.8e-124 Smith-Waterman score: 1940; 100.0% identity (100.0% similar) in 293 aa overlap (131-423:1-293) 110 120 130 140 150 160 pF1KB3 AGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSIHADLCQLCLLAKCFKPALP :::::::::::::::::::::::::::::: XP_005 MQMNTNQLTSIHADLCQLCLLAKCFKPALP 10 20 30 170 180 190 200 210 220 pF1KB3 YLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIM 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB3 LESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVN 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB3 KHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLH 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB3 MIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVN 220 230 240 250 260 270 410 420 pF1KB3 PQFVQKSMGSQEDDSGNKPSSYS ::::::::::::::::::::::: XP_005 PQFVQKSMGSQEDDSGNKPSSYS 280 290 >>NP_001303283 (OMIM: 604665) COP9 signalosome complex s (293 aa) initn: 1940 init1: 1940 opt: 1940 Z-score: 2349.9 bits: 443.3 E(85289): 3.8e-124 Smith-Waterman score: 1940; 100.0% identity (100.0% similar) in 293 aa overlap (131-423:1-293) 110 120 130 140 150 160 pF1KB3 AGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSIHADLCQLCLLAKCFKPALP :::::::::::::::::::::::::::::: NP_001 MQMNTNQLTSIHADLCQLCLLAKCFKPALP 10 20 30 170 180 190 200 210 220 pF1KB3 YLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIM 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB3 LESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVN 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB3 KHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLH 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB3 MIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVN 220 230 240 250 260 270 410 420 pF1KB3 PQFVQKSMGSQEDDSGNKPSSYS ::::::::::::::::::::::: NP_001 PQFVQKSMGSQEDDSGNKPSSYS 280 290 423 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:51:09 2016 done: Sat Nov 5 04:51:10 2016 Total Scan time: 8.270 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]