FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3126, 968 aa 1>>>pF1KB3126 968 - 968 aa - 968 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.9574+/-0.00061; mu= 5.1175+/- 0.038 mean_var=337.9604+/-68.915, 0's: 0 Z-trim(114.9): 439 B-trim: 254 in 1/54 Lambda= 0.069766 statistics sampled from 24593 (25083) to 24593 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.294), width: 16 Scan time: 14.750 The best scores are: opt bits E(85289) NP_001158884 (OMIM: 164011,616576) nuclear factor ( 968) 6407 660.6 1.1e-188 NP_001306155 (OMIM: 164011,616576) nuclear factor ( 968) 6407 660.6 1.1e-188 XP_011530308 (OMIM: 164011,616576) PREDICTED: nucl ( 976) 6407 660.6 1.1e-188 NP_003989 (OMIM: 164011,616576) nuclear factor NF- ( 969) 6395 659.4 2.6e-188 XP_011530310 (OMIM: 164011,616576) PREDICTED: nucl ( 916) 4759 494.7 9.2e-139 XP_011538132 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 923 108.5 1.4e-22 XP_011538133 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 923 108.5 1.4e-22 NP_002493 (OMIM: 164012,615577) nuclear factor NF- ( 899) 923 108.6 1.5e-22 NP_001248332 (OMIM: 164012,615577) nuclear factor ( 899) 923 108.6 1.5e-22 NP_001275653 (OMIM: 164012,615577) nuclear factor ( 899) 923 108.6 1.5e-22 NP_001070962 (OMIM: 164012,615577) nuclear factor ( 900) 923 108.6 1.5e-22 NP_001309863 (OMIM: 164012,615577) nuclear factor ( 900) 923 108.6 1.5e-22 XP_016871767 (OMIM: 164012,615577) PREDICTED: nucl (1081) 923 108.7 1.7e-22 NP_001309864 (OMIM: 164012,615577) nuclear factor ( 858) 589 74.9 2e-12 XP_011531312 (OMIM: 164910) PREDICTED: proto-oncog ( 489) 532 68.9 7.3e-11 XP_005259184 (OMIM: 604758) PREDICTED: transcripti ( 576) 529 68.7 1e-10 NP_006500 (OMIM: 604758) transcription factor RelB ( 579) 529 68.7 1e-10 NP_065390 (OMIM: 164008,612132) NF-kappa-B inhibit ( 317) 458 61.2 9.8e-09 NP_004547 (OMIM: 604548) NF-kappa-B inhibitor epsi ( 500) 452 60.9 2e-08 XP_011525502 (OMIM: 109560) PREDICTED: B-cell lymp ( 378) 437 59.2 4.7e-08 XP_016882598 (OMIM: 109560) PREDICTED: B-cell lymp ( 434) 437 59.3 5.1e-08 XP_011525500 (OMIM: 109560) PREDICTED: B-cell lymp ( 696) 437 59.5 6.9e-08 XP_016882599 (OMIM: 109560) PREDICTED: B-cell lymp ( 356) 403 55.7 4.9e-07 NP_005169 (OMIM: 109560) B-cell lymphoma 3 protein ( 454) 403 55.9 5.7e-07 XP_011525499 (OMIM: 109560) PREDICTED: B-cell lymp ( 539) 403 56.0 6.3e-07 XP_016860116 (OMIM: 164910) PREDICTED: proto-oncog ( 564) 362 51.9 1.1e-05 NP_001278675 (OMIM: 164910) proto-oncogene c-Rel i ( 587) 362 51.9 1.2e-05 NP_002899 (OMIM: 164910) proto-oncogene c-Rel isof ( 619) 362 51.9 1.2e-05 XP_011543509 (OMIM: 164014) PREDICTED: transcripti ( 445) 357 51.2 1.4e-05 NP_001230914 (OMIM: 164014) transcription factor p ( 448) 357 51.2 1.4e-05 XP_011543508 (OMIM: 164014) PREDICTED: transcripti ( 480) 357 51.3 1.5e-05 NP_001230913 (OMIM: 164014) transcription factor p ( 482) 357 51.3 1.5e-05 NP_001138610 (OMIM: 164014) transcription factor p ( 548) 357 51.3 1.6e-05 NP_068810 (OMIM: 164014) transcription factor p65 ( 551) 357 51.3 1.6e-05 XP_016871638 (OMIM: 600465,615493) PREDICTED: anky (1720) 333 49.6 0.00017 XP_016871637 (OMIM: 600465,615493) PREDICTED: anky (1725) 333 49.6 0.00017 XP_016871636 (OMIM: 600465,615493) PREDICTED: anky (1735) 333 49.6 0.00017 XP_016871635 (OMIM: 600465,615493) PREDICTED: anky (1737) 333 49.6 0.00017 XP_016871634 (OMIM: 600465,615493) PREDICTED: anky (1738) 333 49.6 0.00017 XP_016871633 (OMIM: 600465,615493) PREDICTED: anky (1741) 333 49.6 0.00017 XP_016871632 (OMIM: 600465,615493) PREDICTED: anky (1742) 333 49.6 0.00017 XP_016871631 (OMIM: 600465,615493) PREDICTED: anky (1747) 333 49.6 0.00017 XP_016871630 (OMIM: 600465,615493) PREDICTED: anky (1751) 333 49.6 0.00017 XP_016871629 (OMIM: 600465,615493) PREDICTED: anky (1763) 333 49.6 0.00017 XP_016871628 (OMIM: 600465,615493) PREDICTED: anky (1764) 333 49.6 0.00018 XP_016871627 (OMIM: 600465,615493) PREDICTED: anky (1785) 333 49.6 0.00018 XP_016871626 (OMIM: 600465,615493) PREDICTED: anky (1786) 333 49.6 0.00018 XP_016871625 (OMIM: 600465,615493) PREDICTED: anky (1795) 333 49.6 0.00018 XP_016871624 (OMIM: 600465,615493) PREDICTED: anky (1838) 333 49.6 0.00018 XP_016871623 (OMIM: 600465,615493) PREDICTED: anky (1845) 333 49.6 0.00018 >>NP_001158884 (OMIM: 164011,616576) nuclear factor NF-k (968 aa) initn: 6407 init1: 6407 opt: 6407 Z-score: 3508.4 bits: 660.6 E(85289): 1.1e-188 Smith-Waterman score: 6407; 100.0% identity (100.0% similar) in 968 aa overlap (1-968:1-968) 10 20 30 40 50 60 pF1KB3 MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQRGFRFRYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQRGFRFRYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 GICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 EGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 RKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITFH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 PGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNGE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 VTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 ENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVED 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 LLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAMM 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 SNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 TPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMAT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 SWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKLG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 LGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 AHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQ 910 920 930 940 950 960 pF1KB3 EGPLEGKI :::::::: NP_001 EGPLEGKI >>NP_001306155 (OMIM: 164011,616576) nuclear factor NF-k (968 aa) initn: 6407 init1: 6407 opt: 6407 Z-score: 3508.4 bits: 660.6 E(85289): 1.1e-188 Smith-Waterman score: 6407; 100.0% identity (100.0% similar) in 968 aa overlap (1-968:1-968) 10 20 30 40 50 60 pF1KB3 MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQRGFRFRYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQRGFRFRYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 GICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 EGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 RKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITFH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 PGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNGE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 VTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 ENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVED 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 LLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAMM 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 SNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 TPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMAT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 SWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKLG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 LGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 AHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQ 910 920 930 940 950 960 pF1KB3 EGPLEGKI :::::::: NP_001 EGPLEGKI >>XP_011530308 (OMIM: 164011,616576) PREDICTED: nuclear (976 aa) initn: 6407 init1: 6407 opt: 6407 Z-score: 3508.4 bits: 660.6 E(85289): 1.1e-188 Smith-Waterman score: 6407; 100.0% identity (100.0% similar) in 968 aa overlap (1-968:9-976) 10 20 30 40 50 pF1KB3 MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQ :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKRTTSFRMAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 RGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 LVGKHCEDGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVGKHCEDGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 PDLAYLQAEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDLAYLQAEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLE 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 PVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGG 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 VWEGFGDFSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VWEGFGDFSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 IKDKEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKDKEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 TYGGITFHPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TYGGITFHPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPS 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 EATVGNGEVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EATVGNGEVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQ 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 RHLTAVQDENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RHLTAVQDENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVIT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB3 KQEDVVEDLLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQEDVVEDLLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGL 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB3 NAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHV 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB3 DSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPG 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB3 TTPLDMATSWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTPLDMATSWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNW 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB3 ATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAAS 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB3 SPVKTTSQAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPVKTTSQAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLN 910 920 930 940 950 960 960 pF1KB3 KMPHDYGQEGPLEGKI :::::::::::::::: XP_011 KMPHDYGQEGPLEGKI 970 >>NP_003989 (OMIM: 164011,616576) nuclear factor NF-kapp (969 aa) initn: 6393 init1: 6129 opt: 6395 Z-score: 3501.9 bits: 659.4 E(85289): 2.6e-188 Smith-Waterman score: 6395; 99.9% identity (99.9% similar) in 969 aa overlap (1-968:1-969) 10 20 30 40 50 pF1KB3 MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPT-DGPYLQILEQPKQRGFRFRY ::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::: NP_003 MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTADGPYLQILEQPKQRGFRFRY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 VCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 DGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQ 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 AEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAI 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 YDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGD 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 FSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEV 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 QRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITF 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 HPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 HPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNG 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 EVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQ 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 DENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVE 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB3 DLLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DLLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAM 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB3 MSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDG 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB3 TTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMA 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB3 TSWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TSWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKL 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB3 GLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTS 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB3 QAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYG 910 920 930 940 950 960 960 pF1KB3 QEGPLEGKI ::::::::: NP_003 QEGPLEGKI >>XP_011530310 (OMIM: 164011,616576) PREDICTED: nuclear (916 aa) initn: 5023 init1: 4759 opt: 4759 Z-score: 2612.2 bits: 494.7 E(85289): 9.2e-139 Smith-Waterman score: 5944; 94.3% identity (94.4% similar) in 969 aa overlap (1-968:1-916) 10 20 30 40 50 pF1KB3 MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPT-DGPYLQILEQPKQRGFRFRY ::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::: XP_011 MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTADGPYLQILEQPKQRGFRFRY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 VCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 DGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQ 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 AEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAI ::::::::::. XP_011 AEGGGDRQLGE------------------------------------------------- 190 240 250 260 270 280 290 pF1KB3 YDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ----APNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGD 200 210 220 230 240 300 310 320 330 340 350 pF1KB3 FSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEV 250 260 270 280 290 300 360 370 380 390 400 410 pF1KB3 QRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITF 310 320 330 340 350 360 420 430 440 450 460 470 pF1KB3 HPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNG 370 380 390 400 410 420 480 490 500 510 520 530 pF1KB3 EVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQ 430 440 450 460 470 480 540 550 560 570 580 590 pF1KB3 DENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVE 490 500 510 520 530 540 600 610 620 630 640 650 pF1KB3 DLLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAM 550 560 570 580 590 600 660 670 680 690 700 710 pF1KB3 MSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDG 610 620 630 640 650 660 720 730 740 750 760 770 pF1KB3 TTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMA 670 680 690 700 710 720 780 790 800 810 820 830 pF1KB3 TSWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKL 730 740 750 760 770 780 840 850 860 870 880 890 pF1KB3 GLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTS 790 800 810 820 830 840 900 910 920 930 940 950 pF1KB3 QAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYG 850 860 870 880 890 900 960 pF1KB3 QEGPLEGKI ::::::::: XP_011 QEGPLEGKI 910 >>XP_011538132 (OMIM: 164012,615577) PREDICTED: nuclear (755 aa) initn: 1303 init1: 463 opt: 923 Z-score: 526.5 bits: 108.5 E(85289): 1.4e-22 Smith-Waterman score: 1703; 42.5% identity (67.7% similar) in 730 aa overlap (188-901:21-715) 160 170 180 190 200 210 pF1KB3 TEACIRGYNPGLLVHPDLAYLQAEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFT : . :.. ..: : . : ::::.::: :. XP_011 MMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFS 10 20 30 40 50 220 230 240 250 260 270 pF1KB3 AFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQK ::: : :::. :.::.:. :.:::.:.:::::: :::.::: : ::.:.::::::::: XP_011 AFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQK 60 70 80 90 100 110 280 290 300 310 320 330 pF1KB3 DDIQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKS :::..::::..::: :..::::::::::.:.::::.:: :. ..: .:..::.::.:: XP_011 DDIEVRFYEDDENG--WQAFGDFSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKR 120 130 140 150 160 340 350 360 370 380 390 pF1KB3 DLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGT ..:. : : ::: ..:::::::::.: .:.::. ::::: :.:.:: :. ::.:: XP_011 GGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGSGGAAGGYGGAGGG 170 180 190 200 210 220 400 410 420 430 440 450 pF1KB3 GSTGPGYSFPHYGFPTYGGITFHPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNL :: : : ::. .... : .:.:: : :: . .. XP_011 GSLG----F----FPS--SLAYSP--YQSGAG-------------PMGCYPGGGGGA--Q 230 240 250 260 460 470 480 490 500 510 pF1KB3 FGKVIETTEQDQEPSEATVGNGEVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALF .. .. . .. .: .: .. . : . . . . . ::.: : ::. XP_011 MAATVPSRDSGEEAAEPSAP----SRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALL 270 280 290 300 310 520 530 540 550 560 570 pF1KB3 DYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINM ::.::.:.. ::: :::: ..::::::. ::::::: ......... : . ..:. XP_011 DYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNL 320 330 340 350 360 370 580 590 600 610 620 630 pF1KB3 RNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVLHLA--AKEGHDKVLSILL : :.:::::::::: : .:: :::.::: .:::: :.:..::: : : ..: :: XP_011 TNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALL 380 390 400 410 420 430 640 650 660 670 680 690 pF1KB3 KHKKAAL--LLDHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAV . :. :: :. .:: .:::. . : :: ::: .::.:.: :...::::::::. XP_011 QSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLAT 440 450 460 470 480 490 700 710 720 730 740 750 pF1KB3 EHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPL : ....:. :. . :.:.. :. :.::::.::: : :. :: :::: .:: ::: XP_011 EMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPL 500 510 520 530 540 550 760 770 780 790 800 pF1KB3 YDL------DDSWENAGEDEGVVP---GTTPLDMATSWQVFDIL-NG--KPYEPEFTSDD : :.. .. : .. . : ::::.. : .: .: :. . .:: .: . XP_011 CPLPSPPTSDSDSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPS 560 570 580 590 600 610 810 820 830 840 850 860 pF1KB3 LLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDN : .:.. . .: .::. :. . .:: ::..::: : ...: . .:: .:. . XP_011 --PAGPGLSLGDTALQNLEQLLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRS 620 630 640 650 660 670 870 880 890 900 910 920 pF1KB3 YEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQAHSLPLSPASTRQQIDELRDS ::..:: . :.::: .:: :....... . : : : XP_011 YELAGGDLAGLLEALSDMGLEEGVRLLRGPETRDKLPSTAEVKEDSAYGSQSVEQEAEKL 680 690 700 710 720 730 930 940 950 960 pF1KB3 DSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQEGPLEGKI XP_011 GPPPEPPGGLCHGHPQPQVH 740 750 >>XP_011538133 (OMIM: 164012,615577) PREDICTED: nuclear (755 aa) initn: 1303 init1: 463 opt: 923 Z-score: 526.5 bits: 108.5 E(85289): 1.4e-22 Smith-Waterman score: 1703; 42.5% identity (67.7% similar) in 730 aa overlap (188-901:21-715) 160 170 180 190 200 210 pF1KB3 TEACIRGYNPGLLVHPDLAYLQAEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFT : . :.. ..: : . : ::::.::: :. XP_011 MMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFS 10 20 30 40 50 220 230 240 250 260 270 pF1KB3 AFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQK ::: : :::. :.::.:. :.:::.:.:::::: :::.::: : ::.:.::::::::: XP_011 AFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQK 60 70 80 90 100 110 280 290 300 310 320 330 pF1KB3 DDIQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKS :::..::::..::: :..::::::::::.:.::::.:: :. ..: .:..::.::.:: XP_011 DDIEVRFYEDDENG--WQAFGDFSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKR 120 130 140 150 160 340 350 360 370 380 390 pF1KB3 DLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGT ..:. : : ::: ..:::::::::.: .:.::. ::::: :.:.:: :. ::.:: XP_011 GGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGSGGAAGGYGGAGGG 170 180 190 200 210 220 400 410 420 430 440 450 pF1KB3 GSTGPGYSFPHYGFPTYGGITFHPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNL :: : : ::. .... : .:.:: : :: . .. XP_011 GSLG----F----FPS--SLAYSP--YQSGAG-------------PMGCYPGGGGGA--Q 230 240 250 260 460 470 480 490 500 510 pF1KB3 FGKVIETTEQDQEPSEATVGNGEVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALF .. .. . .. .: .: .. . : . . . . . ::.: : ::. XP_011 MAATVPSRDSGEEAAEPSAP----SRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALL 270 280 290 300 310 520 530 540 550 560 570 pF1KB3 DYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINM ::.::.:.. ::: :::: ..::::::. ::::::: ......... : . ..:. XP_011 DYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNL 320 330 340 350 360 370 580 590 600 610 620 630 pF1KB3 RNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVLHLA--AKEGHDKVLSILL : :.:::::::::: : .:: :::.::: .:::: :.:..::: : : ..: :: XP_011 TNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALL 380 390 400 410 420 430 640 650 660 670 680 690 pF1KB3 KHKKAAL--LLDHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAV . :. :: :. .:: .:::. . : :: ::: .::.:.: :...::::::::. XP_011 QSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLAT 440 450 460 470 480 490 700 710 720 730 740 750 pF1KB3 EHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPL : ....:. :. . :.:.. :. :.::::.::: : :. :: :::: .:: ::: XP_011 EMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPL 500 510 520 530 540 550 760 770 780 790 800 pF1KB3 YDL------DDSWENAGEDEGVVP---GTTPLDMATSWQVFDIL-NG--KPYEPEFTSDD : :.. .. : .. . : ::::.. : .: .: :. . .:: .: . XP_011 CPLPSPPTSDSDSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPS 560 570 580 590 600 610 810 820 830 840 850 860 pF1KB3 LLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDN : .:.. . .: .::. :. . .:: ::..::: : ...: . .:: .:. . XP_011 --PAGPGLSLGDTALQNLEQLLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRS 620 630 640 650 660 670 870 880 890 900 910 920 pF1KB3 YEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQAHSLPLSPASTRQQIDELRDS ::..:: . :.::: .:: :....... . : : : XP_011 YELAGGDLAGLLEALSDMGLEEGVRLLRGPETRDKLPSTAEVKEDSAYGSQSVEQEAEKL 680 690 700 710 720 730 930 940 950 960 pF1KB3 DSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQEGPLEGKI XP_011 GPPPEPPGGLCHGHPQPQVH 740 750 >>NP_002493 (OMIM: 164012,615577) nuclear factor NF-kapp (899 aa) initn: 1759 init1: 463 opt: 923 Z-score: 525.7 bits: 108.6 E(85289): 1.5e-22 Smith-Waterman score: 2240; 44.7% identity (68.5% similar) in 899 aa overlap (18-899:17-858) 10 20 30 40 50 60 pF1KB3 MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQRGFRFRYV : .:. .: .:. :. : ::::: :.:::::::::::: NP_002 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETA---DGPYLVIVEQPKQRGFRFRYG 10 20 30 40 50 70 80 90 100 110 pF1KB3 CEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHC-E ::::::::::::::::..:.:: :::::: ::::. :.:::.. . ::::::::.: : NP_002 CEGPSHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 DGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQ :::.:..:::::.. : :::.::::::... :. .. . .:. :: . NP_002 LGICAVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLT--------E 120 130 140 150 160 180 190 200 210 220 230 pF1KB3 AEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAI :: .:.: .. ::: : ::::.::: :.::: : :::. :.::.:. : NP_002 AE---QRELEQEAKEL--------KKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPI 170 180 190 200 210 240 250 260 270 280 290 pF1KB3 YDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGD .:::.:.:::::: :::.::: : ::.:.::::::::::::..::::..::: :..::: NP_002 HDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENG--WQAFGD 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB3 FSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEV :::::::.:.::::.:: :. ..: .:..::.::.:: ..:. : : ::: ..::::: NP_002 FSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEV 280 290 300 310 320 330 360 370 380 390 400 410 pF1KB3 QRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITF ::::.: .:.::. ::::: :.:.:: :. ::.:: :: : : ::. .... NP_002 QRKRRKALPTFSQPFGGGSHMGGGSGGAAGGYGGAGGGGSLG----F----FPS--SLAY 340 350 360 370 380 420 430 440 450 460 470 pF1KB3 HPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNG : .:.:: : :: . .. .. .. . .. .: .: .. NP_002 SP--YQSGAG-------------PMGCYPGGGGGA--QMAATVPSRDSGEEAAEPSAP-- 390 400 410 420 480 490 500 510 520 530 pF1KB3 EVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQ . : . . . . . ::.: : ::.::.::.:.. ::: :::: ..: NP_002 --SRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHLLTAQ 430 440 450 460 470 480 540 550 560 570 580 590 pF1KB3 DENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVE :::::. ::::::: ......... : . ..:. : :.:::::::::: : .:: NP_002 DENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVS 490 500 510 520 530 540 600 610 620 630 640 650 pF1KB3 DLLRAGADLSLLDRLGNSVLHLA--AKEGHDKVLSILLKHKKAAL--LLDHPNGDGLNAI :::.::: .:::: :.:..::: : : ..: ::. :. :: :. .:: . NP_002 FLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPV 550 560 570 580 590 600 660 670 680 690 700 710 pF1KB3 HLAMMSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDST :::. . : :: ::: .::.:.: :...::::::::.: ....:. :. . :.:.. NP_002 HLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR 610 620 630 640 650 660 720 730 740 750 760 pF1KB3 TYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDL------DDSWENAGEDEGV :. :.::::.::: : :. :: :::: .:: ::: : :.. .. : .. . NP_002 TFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDT 670 680 690 700 710 720 770 780 790 800 810 820 pF1KB3 VP---GTTPLDMATSWQVFDIL-NG--KPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLL : ::::.. : .: .: :. . .:: .: . : .:.. . .: .:: NP_002 RSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPS--PAGPGLSLGDTALQNLEQLL 730 740 750 760 770 780 830 840 850 860 870 880 pF1KB3 EIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTE . :. . .:: ::..::: : ...: . .:: .:. .::..:: . :.::: .:: : NP_002 DGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGLEE 790 800 810 820 830 840 890 900 910 920 930 940 pF1KB3 AIEVIQAASSPVKTTSQAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLT ....... . : : NP_002 GVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH 850 860 870 880 890 >>NP_001248332 (OMIM: 164012,615577) nuclear factor NF-k (899 aa) initn: 1759 init1: 463 opt: 923 Z-score: 525.7 bits: 108.6 E(85289): 1.5e-22 Smith-Waterman score: 2240; 44.7% identity (68.5% similar) in 899 aa overlap (18-899:17-858) 10 20 30 40 50 60 pF1KB3 MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQRGFRFRYV : .:. .: .:. :. : ::::: :.:::::::::::: NP_001 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETA---DGPYLVIVEQPKQRGFRFRYG 10 20 30 40 50 70 80 90 100 110 pF1KB3 CEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHC-E ::::::::::::::::..:.:: :::::: ::::. :.:::.. . ::::::::.: : NP_001 CEGPSHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 DGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQ :::.:..:::::.. : :::.::::::... :. .. . .:. :: . NP_001 LGICAVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLT--------E 120 130 140 150 160 180 190 200 210 220 230 pF1KB3 AEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAI :: .:.: .. ::: : ::::.::: :.::: : :::. :.::.:. : NP_001 AE---QRELEQEAKEL--------KKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPI 170 180 190 200 210 240 250 260 270 280 290 pF1KB3 YDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGD .:::.:.:::::: :::.::: : ::.:.::::::::::::..::::..::: :..::: NP_001 HDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENG--WQAFGD 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB3 FSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEV :::::::.:.::::.:: :. ..: .:..::.::.:: ..:. : : ::: ..::::: NP_001 FSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEV 280 290 300 310 320 330 360 370 380 390 400 410 pF1KB3 QRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITF ::::.: .:.::. ::::: :.:.:: :. ::.:: :: : : ::. .... NP_001 QRKRRKALPTFSQPFGGGSHMGGGSGGAAGGYGGAGGGGSLG----F----FPS--SLAY 340 350 360 370 380 420 430 440 450 460 470 pF1KB3 HPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNG : .:.:: : :: . .. .. .. . .. .: .: .. NP_001 SP--YQSGAG-------------PMGCYPGGGGGA--QMAATVPSRDSGEEAAEPSAP-- 390 400 410 420 480 490 500 510 520 530 pF1KB3 EVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQ . : . . . . . ::.: : ::.::.::.:.. ::: :::: ..: NP_001 --SRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHLLTAQ 430 440 450 460 470 480 540 550 560 570 580 590 pF1KB3 DENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVE :::::. ::::::: ......... : . ..:. : :.:::::::::: : .:: NP_001 DENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVS 490 500 510 520 530 540 600 610 620 630 640 650 pF1KB3 DLLRAGADLSLLDRLGNSVLHLA--AKEGHDKVLSILLKHKKAAL--LLDHPNGDGLNAI :::.::: .:::: :.:..::: : : ..: ::. :. :: :. .:: . NP_001 FLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPV 550 560 570 580 590 600 660 670 680 690 700 710 pF1KB3 HLAMMSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDST :::. . : :: ::: .::.:.: :...::::::::.: ....:. :. . :.:.. NP_001 HLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR 610 620 630 640 650 660 720 730 740 750 760 pF1KB3 TYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDL------DDSWENAGEDEGV :. :.::::.::: : :. :: :::: .:: ::: : :.. .. : .. . NP_001 TFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDT 670 680 690 700 710 720 770 780 790 800 810 820 pF1KB3 VP---GTTPLDMATSWQVFDIL-NG--KPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLL : ::::.. : .: .: :. . .:: .: . : .:.. . .: .:: NP_001 RSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPS--PAGPGLSLGDTALQNLEQLL 730 740 750 760 770 780 830 840 850 860 870 880 pF1KB3 EIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTE . :. . .:: ::..::: : ...: . .:: .:. .::..:: . :.::: .:: : NP_001 DGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGLEE 790 800 810 820 830 840 890 900 910 920 930 940 pF1KB3 AIEVIQAASSPVKTTSQAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLT ....... . : : NP_001 GVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH 850 860 870 880 890 >>NP_001275653 (OMIM: 164012,615577) nuclear factor NF-k (899 aa) initn: 1759 init1: 463 opt: 923 Z-score: 525.7 bits: 108.6 E(85289): 1.5e-22 Smith-Waterman score: 2240; 44.7% identity (68.5% similar) in 899 aa overlap (18-899:17-858) 10 20 30 40 50 60 pF1KB3 MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQRGFRFRYV : .:. .: .:. :. : ::::: :.:::::::::::: NP_001 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETA---DGPYLVIVEQPKQRGFRFRYG 10 20 30 40 50 70 80 90 100 110 pF1KB3 CEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHC-E ::::::::::::::::..:.:: :::::: ::::. :.:::.. . ::::::::.: : NP_001 CEGPSHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 DGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQ :::.:..:::::.. : :::.::::::... :. .. . .:. :: . NP_001 LGICAVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLT--------E 120 130 140 150 160 180 190 200 210 220 230 pF1KB3 AEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAI :: .:.: .. ::: : ::::.::: :.::: : :::. :.::.:. : NP_001 AE---QRELEQEAKEL--------KKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPI 170 180 190 200 210 240 250 260 270 280 290 pF1KB3 YDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGD .:::.:.:::::: :::.::: : ::.:.::::::::::::..::::..::: :..::: NP_001 HDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENG--WQAFGD 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB3 FSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEV :::::::.:.::::.:: :. ..: .:..::.::.:: ..:. : : ::: ..::::: NP_001 FSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEV 280 290 300 310 320 330 360 370 380 390 400 410 pF1KB3 QRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITF ::::.: .:.::. ::::: :.:.:: :. ::.:: :: : : ::. .... NP_001 QRKRRKALPTFSQPFGGGSHMGGGSGGAAGGYGGAGGGGSLG----F----FPS--SLAY 340 350 360 370 380 420 430 440 450 460 470 pF1KB3 HPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNG : .:.:: : :: . .. .. .. . .. .: .: .. NP_001 SP--YQSGAG-------------PMGCYPGGGGGA--QMAATVPSRDSGEEAAEPSAP-- 390 400 410 420 480 490 500 510 520 530 pF1KB3 EVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQ . : . . . . . ::.: : ::.::.::.:.. ::: :::: ..: NP_001 --SRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHLLTAQ 430 440 450 460 470 480 540 550 560 570 580 590 pF1KB3 DENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVE :::::. ::::::: ......... : . ..:. : :.:::::::::: : .:: NP_001 DENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVS 490 500 510 520 530 540 600 610 620 630 640 650 pF1KB3 DLLRAGADLSLLDRLGNSVLHLA--AKEGHDKVLSILLKHKKAAL--LLDHPNGDGLNAI :::.::: .:::: :.:..::: : : ..: ::. :. :: :. .:: . NP_001 FLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPV 550 560 570 580 590 600 660 670 680 690 700 710 pF1KB3 HLAMMSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDST :::. . : :: ::: .::.:.: :...::::::::.: ....:. :. . :.:.. NP_001 HLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR 610 620 630 640 650 660 720 730 740 750 760 pF1KB3 TYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDL------DDSWENAGEDEGV :. :.::::.::: : :. :: :::: .:: ::: : :.. .. : .. . NP_001 TFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDT 670 680 690 700 710 720 770 780 790 800 810 820 pF1KB3 VP---GTTPLDMATSWQVFDIL-NG--KPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLL : ::::.. : .: .: :. . .:: .: . : .:.. . .: .:: NP_001 RSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPS--PAGPGLSLGDTALQNLEQLL 730 740 750 760 770 780 830 840 850 860 870 880 pF1KB3 EIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTE . :. . .:: ::..::: : ...: . .:: .:. .::..:: . :.::: .:: : NP_001 DGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGLEE 790 800 810 820 830 840 890 900 910 920 930 940 pF1KB3 AIEVIQAASSPVKTTSQAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLT ....... . : : NP_001 GVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH 850 860 870 880 890 968 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:26:00 2016 done: Sat Nov 5 02:26:02 2016 Total Scan time: 14.750 Total Display time: 0.410 Function used was FASTA [36.3.4 Apr, 2011]