FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3129, 239 aa 1>>>pF1KB3129 239 - 239 aa - 239 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.4042+/-0.000876; mu= 2.9478+/- 0.053 mean_var=208.6209+/-41.594, 0's: 0 Z-trim(114.8): 17 B-trim: 0 in 0/52 Lambda= 0.088796 statistics sampled from 15302 (15319) to 15302 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.471), width: 16 Scan time: 2.600 The best scores are: opt bits E(32554) CCDS11981.1 BCL2 gene_id:596|Hs108|chr18 ( 239) 1659 224.0 7e-59 CCDS45882.1 BCL2 gene_id:596|Hs108|chr18 ( 205) 1366 186.4 1.2e-47 CCDS13189.1 BCL2L1 gene_id:598|Hs108|chr20 ( 233) 599 88.2 5.2e-18 CCDS9591.1 BCL2L2 gene_id:599|Hs108|chr14 ( 193) 515 77.3 7.8e-15 CCDS55906.1 PABPN1 gene_id:100529063|Hs108|chr14 ( 333) 437 67.6 1.2e-11 >>CCDS11981.1 BCL2 gene_id:596|Hs108|chr18 (239 aa) initn: 1659 init1: 1659 opt: 1659 Z-score: 1170.6 bits: 224.0 E(32554): 7e-59 Smith-Waterman score: 1659; 100.0% identity (100.0% similar) in 239 aa overlap (1-239:1-239) 10 20 30 40 50 60 pF1KB3 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK 190 200 210 220 230 >>CCDS45882.1 BCL2 gene_id:596|Hs108|chr18 (205 aa) initn: 1366 init1: 1366 opt: 1366 Z-score: 968.6 bits: 186.4 E(32554): 1.2e-47 Smith-Waterman score: 1366; 100.0% identity (100.0% similar) in 195 aa overlap (1-195:1-195) 10 20 30 40 50 60 pF1KB3 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK ::::::::::::::: CCDS45 LNRHLHTWIQDNGGWVGALGDVSLG 190 200 >>CCDS13189.1 BCL2L1 gene_id:598|Hs108|chr20 (233 aa) initn: 606 init1: 524 opt: 599 Z-score: 436.8 bits: 88.2 E(32554): 5.2e-18 Smith-Waterman score: 599; 51.0% identity (72.0% similar) in 200 aa overlap (11-203:5-196) 10 20 30 40 50 pF1KB3 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDA-GDVGAAPPGAAPAP-GIFSSQPGHTPH :::.:. .. :::::.:: :. .:: . . :: : : . .:: CCDS13 MSQSNRELVVDFLSYKLSQKGYSWSQFSDV---EENRTEAPEGTESEM--ETPS 10 20 30 40 60 70 80 90 100 110 pF1KB3 PAASRDPVARTSPLQTPAAPGAAAGP----ALSPVP-PVVHLTLRQAGDDFSRRYRRDFA : . .: . . ..::. ::.. : .: .:. .::.:::.: :::: :. CCDS13 -AINGNPSWHLA--DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFS 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB3 EMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNI ...::::.:: :: : ::.:::::::::::::::: :::..:::::..::. ::. : CCDS13 DLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRI 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB3 ALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLG : ::. ::: ::. :::.:::::.:::::: CCDS13 AAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLL 170 180 190 200 210 220 >>CCDS9591.1 BCL2L2 gene_id:599|Hs108|chr14 (193 aa) initn: 490 init1: 460 opt: 515 Z-score: 379.8 bits: 77.3 E(32554): 7.8e-15 Smith-Waterman score: 515; 45.4% identity (74.8% similar) in 163 aa overlap (82-239:31-193) 60 70 80 90 100 110 pF1KB3 QPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRD :::. .:. .: ..: :::.: :.:: CCDS95 MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRT 10 20 30 40 50 60 120 130 140 150 160 170 pF1KB3 FAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVD :.....:::.:: .:. ::. : .:::. : ::::.:::: ::...:.::::.:: ::: CCDS95 FSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVG 70 80 90 100 110 120 180 190 200 210 220 pF1KB3 NIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSM----RPLFDFSWLSLKTLLSLAL-V .. ::. ::. .: ::...::: :. ::: . : : . .: :..:.:. :. . CCDS95 QVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVAL 130 140 150 160 170 180 230 pF1KB3 GACITLGAYLGHK :: .:.::... : CCDS95 GALVTVGAFFASK 190 >>CCDS55906.1 PABPN1 gene_id:100529063|Hs108|chr14 (333 aa) initn: 514 init1: 437 opt: 437 Z-score: 322.6 bits: 67.6 E(32554): 1.2e-11 Smith-Waterman score: 437; 49.6% identity (79.1% similar) in 115 aa overlap (82-196:31-145) 60 70 80 90 100 110 pF1KB3 QPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRD :::. .:. .: ..: :::.: :.:: CCDS55 MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRT 10 20 30 40 50 60 120 130 140 150 160 170 pF1KB3 FAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVD :.....:::.:: .:. ::. : .:::. : ::::.:::: ::...:.::::.:: ::: CCDS55 FSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVG 70 80 90 100 110 120 180 190 200 210 220 230 pF1KB3 NIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACIT .. ::. ::. .: ::...:::. CCDS55 QVQEWMVAYLETQLADWIHSSGGWELEAIKARVREMEEEAEKLKELQNEVEKQMNMSPPP 130 140 150 160 170 180 239 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:29:35 2016 done: Thu Nov 3 12:29:36 2016 Total Scan time: 2.600 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]