FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3168, 790 aa
1>>>pF1KB3168 790 - 790 aa - 790 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3784+/-0.000327; mu= 17.9679+/- 0.021
mean_var=140.8070+/-29.063, 0's: 0 Z-trim(118.8): 29 B-trim: 9 in 1/56
Lambda= 0.108084
statistics sampled from 32192 (32221) to 32192 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.378), width: 16
Scan time: 13.430
The best scores are: opt bits E(85289)
NP_001257437 (OMIM: 191163,616744) tumor necrosis ( 790) 5584 882.8 0
XP_011534397 (OMIM: 191163,616744) PREDICTED: tumo ( 790) 5584 882.8 0
NP_006281 (OMIM: 191163,616744) tumor necrosis fac ( 790) 5584 882.8 0
XP_005267176 (OMIM: 191163,616744) PREDICTED: tumo ( 790) 5584 882.8 0
NP_001257436 (OMIM: 191163,616744) tumor necrosis ( 790) 5584 882.8 0
XP_011534398 (OMIM: 191163,616744) PREDICTED: tumo ( 689) 4453 706.4 1.1e-202
XP_006715618 (OMIM: 191163,616744) PREDICTED: tumo ( 577) 4142 657.8 3.8e-188
NP_570971 (OMIM: 612024) OTU domain-containing pro ( 926) 555 98.7 1.2e-19
NP_001316836 (OMIM: 612024) OTU domain-containing ( 425) 377 70.6 1.6e-11
XP_016857340 (OMIM: 611748) PREDICTED: OTU domain- ( 714) 344 65.6 8.3e-10
XP_016857339 (OMIM: 611748) PREDICTED: OTU domain- ( 764) 344 65.7 8.7e-10
XP_011508089 (OMIM: 611748) PREDICTED: OTU domain- ( 773) 344 65.7 8.8e-10
XP_011508090 (OMIM: 611748) PREDICTED: OTU domain- ( 773) 344 65.7 8.8e-10
XP_011508088 (OMIM: 611748) PREDICTED: OTU domain- ( 773) 344 65.7 8.8e-10
NP_064590 (OMIM: 611748) OTU domain-containing pro ( 843) 344 65.7 9.3e-10
XP_011508085 (OMIM: 611748) PREDICTED: OTU domain- ( 852) 344 65.7 9.4e-10
XP_011508087 (OMIM: 611748) PREDICTED: OTU domain- ( 852) 344 65.7 9.4e-10
XP_011508084 (OMIM: 611748) PREDICTED: OTU domain- ( 852) 344 65.7 9.4e-10
XP_011508086 (OMIM: 611748) PREDICTED: OTU domain- ( 852) 344 65.7 9.4e-10
XP_016871847 (OMIM: 611749) PREDICTED: ubiquitin t ( 382) 267 53.4 2.2e-06
XP_016871846 (OMIM: 611749) PREDICTED: ubiquitin t ( 708) 267 53.6 3.4e-06
XP_005269983 (OMIM: 611749) PREDICTED: ubiquitin t ( 708) 267 53.6 3.4e-06
NP_060050 (OMIM: 611749) ubiquitin thioesterase ZR ( 708) 267 53.6 3.4e-06
XP_005269982 (OMIM: 611749) PREDICTED: ubiquitin t ( 734) 267 53.7 3.5e-06
XP_006717970 (OMIM: 611749) PREDICTED: ubiquitin t ( 734) 267 53.7 3.5e-06
XP_011538189 (OMIM: 611749) PREDICTED: ubiquitin t ( 248) 248 50.2 1.3e-05
>>NP_001257437 (OMIM: 191163,616744) tumor necrosis fact (790 aa)
initn: 5584 init1: 5584 opt: 5584 Z-score: 4712.4 bits: 882.8 E(85289): 0
Smith-Waterman score: 5584; 100.0% identity (100.0% similar) in 790 aa overlap (1-790:1-790)
10 20 30 40 50 60
pF1KB3 MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 REIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 MARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 PGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 KRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 ECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARAS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 CKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCN
730 740 750 760 770 780
790
pF1KB3 ECFQFKQMYG
::::::::::
NP_001 ECFQFKQMYG
790
>>XP_011534397 (OMIM: 191163,616744) PREDICTED: tumor ne (790 aa)
initn: 5584 init1: 5584 opt: 5584 Z-score: 4712.4 bits: 882.8 E(85289): 0
Smith-Waterman score: 5584; 100.0% identity (100.0% similar) in 790 aa overlap (1-790:1-790)
10 20 30 40 50 60
pF1KB3 MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 REIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 MARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 PGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 KRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 ECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARAS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 CKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCN
730 740 750 760 770 780
790
pF1KB3 ECFQFKQMYG
::::::::::
XP_011 ECFQFKQMYG
790
>>NP_006281 (OMIM: 191163,616744) tumor necrosis factor (790 aa)
initn: 5584 init1: 5584 opt: 5584 Z-score: 4712.4 bits: 882.8 E(85289): 0
Smith-Waterman score: 5584; 100.0% identity (100.0% similar) in 790 aa overlap (1-790:1-790)
10 20 30 40 50 60
pF1KB3 MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 REIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 REIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 MARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 PGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 KRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 ECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARAS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 CKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCN
730 740 750 760 770 780
790
pF1KB3 ECFQFKQMYG
::::::::::
NP_006 ECFQFKQMYG
790
>>XP_005267176 (OMIM: 191163,616744) PREDICTED: tumor ne (790 aa)
initn: 5584 init1: 5584 opt: 5584 Z-score: 4712.4 bits: 882.8 E(85289): 0
Smith-Waterman score: 5584; 100.0% identity (100.0% similar) in 790 aa overlap (1-790:1-790)
10 20 30 40 50 60
pF1KB3 MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 REIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 MARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 PGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 KRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 ECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARAS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 CKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCN
730 740 750 760 770 780
790
pF1KB3 ECFQFKQMYG
::::::::::
XP_005 ECFQFKQMYG
790
>>NP_001257436 (OMIM: 191163,616744) tumor necrosis fact (790 aa)
initn: 5584 init1: 5584 opt: 5584 Z-score: 4712.4 bits: 882.8 E(85289): 0
Smith-Waterman score: 5584; 100.0% identity (100.0% similar) in 790 aa overlap (1-790:1-790)
10 20 30 40 50 60
pF1KB3 MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 REIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 MARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 PGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 KRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 ECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARAS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 CKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCN
730 740 750 760 770 780
790
pF1KB3 ECFQFKQMYG
::::::::::
NP_001 ECFQFKQMYG
790
>>XP_011534398 (OMIM: 191163,616744) PREDICTED: tumor ne (689 aa)
initn: 4610 init1: 4450 opt: 4453 Z-score: 3760.0 bits: 706.4 E(85289): 1.1e-202
Smith-Waterman score: 4453; 96.7% identity (98.3% similar) in 662 aa overlap (1-661:1-662)
10 20 30 40 50 60
pF1KB3 MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 REIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 MARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 PGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 KRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGD
550 560 570 580 590 600
610 620 630 640 650
pF1KB3 RTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTI-PCLG
:::::::::::::::::::::::::::::::::::.. :. .: ..... . : :
XP_011 RTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKQIEPAQRCASNHTKHLKAQVRPGLL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB3 RECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARA
.:
XP_011 QEHPGLPQRGALHGVSASQPEDGPWGPPG
670 680
>>XP_006715618 (OMIM: 191163,616744) PREDICTED: tumor ne (577 aa)
initn: 4142 init1: 4142 opt: 4142 Z-score: 3498.9 bits: 657.8 E(85289): 3.8e-188
Smith-Waterman score: 4142; 100.0% identity (100.0% similar) in 577 aa overlap (214-790:1-577)
190 200 210 220 230 240
pF1KB3 SGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQEC
::::::::::::::::::::::::::::::
XP_006 MLRSLESGSNFAPLKVGGIYLPLHWPAQEC
10 20 30
250 260 270 280 290 300
pF1KB3 YRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLL
40 50 60 70 80 90
310 320 330 340 350 360
pF1KB3 KEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQG
100 110 120 130 140 150
370 380 390 400 410 420
pF1KB3 RREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPKLNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPKLNS
160 170 180 190 200 210
430 440 450 460 470 480
pF1KB3 KPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRSPGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRSPGC
220 230 240 250 260 270
490 500 510 520 530 540
pF1KB3 PFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCFKRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCFKRT
280 290 300 310 320 330
550 560 570 580 590 600
pF1KB3 TAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGDRTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGDRTG
340 350 360 370 380 390
610 620 630 640 650 660
pF1KB3 TSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGRECG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGRECG
400 410 420 430 440 450
670 680 690 700 710 720
pF1KB3 TLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARASCKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARASCKN
460 470 480 490 500 510
730 740 750 760 770 780
pF1KB3 ILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCNECF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCNECF
520 530 540 550 560 570
790
pF1KB3 QFKQMYG
:::::::
XP_006 QFKQMYG
>>NP_570971 (OMIM: 612024) OTU domain-containing protein (926 aa)
initn: 531 init1: 162 opt: 555 Z-score: 473.4 bits: 98.7 E(85289): 1.2e-19
Smith-Waterman score: 593; 38.2% identity (65.8% similar) in 272 aa overlap (43-294:146-404)
20 30 40 50 60 70
pF1KB3 SNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRN
: ::... . .:: .:.. ::..
NP_570 RGISHASSAIVSLARSHVASECNNEQFPLEMPIYTFQLPDLSVYSEDFRSFIERDLIEQA
120 130 140 150 160 170
80 90 100 110 120
pF1KB3 IQATLESQKKLNW----CREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFS
...::. .::: : ..:. : :.::::::.::.: ::: .: ::::::::..
NP_570 TMVALEQAGRLNWWSTVCTSCKRLLPLATTGDGNCLLHAASLGMWGFHDRDLVLRKALYT
180 190 200 210 220 230
130 140 150 160 170 180
pF1KB3 TLKETDTRN-FKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTD--TPMARSG
.. :. .: ::. . ..:. : ..:. :: .:.:.::.. : ....:
NP_570 MMRTGAEREALKRRWRWQ--QTQQNKE-------EEWEREWTELLKLASSEPRTHFSKNG
240 250 260 270 280
190 200 210 220 230
pF1KB3 LQ-----------YNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYL
:.::::.:.::: .::::::.:..: :::. .: :::. :::::
NP_570 GTGGGVDNSEDPVYESLEEFHVFVLAHILRRPIVVVADTMLRD-SGGEAFAPIPFGGIYL
290 300 310 320 330 340
240 250 260 270 280 290
pF1KB3 PLHWPAQECYRYPIVLGYDSHHFVPLVTL--KDSGPEIRAVPLVNRDRGRFEDLKVHFLT
::. : ..:. :.::.::. :: ::.. .:. : ..::.. .. . : .:: .
NP_570 PLEVPPNRCHCSPLVLAYDQAHFSALVSMEQRDQQREQAVIPLTDSEH---KLLPLHFAV
350 360 370 380 390 400
300 310 320 330 340 350
pF1KB3 DPENEMKEKLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHE
::
NP_570 DPGKDWEWGKDDNDNARLAHLILSLEAKLNLLHSYMNVTWIRIPSETRAPLAQPESPTAS
410 420 430 440 450 460
>>NP_001316836 (OMIM: 612024) OTU domain-containing prot (425 aa)
initn: 599 init1: 192 opt: 377 Z-score: 327.6 bits: 70.6 E(85289): 1.6e-11
Smith-Waterman score: 603; 40.8% identity (68.3% similar) in 240 aa overlap (43-264:146-382)
20 30 40 50 60 70
pF1KB3 SNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRN
: ::... . .:: .:.. ::..
NP_001 RGISHASSAIVSLARSHVASECNNEQFPLEMPIYTFQLPDLSVYSEDFRSFIERDLIEQA
120 130 140 150 160 170
80 90 100 110 120
pF1KB3 IQATLESQKKLNW----CREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFS
...::. .::: : ..:. : :.::::::.::.: ::: .: ::::::::..
NP_001 TMVALEQAGRLNWWSTVCTSCKRLLPLATTGDGNCLLHAASLGMWGFHDRDLVLRKALYT
180 190 200 210 220 230
130 140 150 160 170 180
pF1KB3 TLKETDTRN-FKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTD--TPMARSG
.. :. .: ::. . ..:. :.:: : ..:. :: .:.:.::.. : ....:
NP_001 MMRTGAEREALKRRWRWQ--QTQQNKESGLVYTEEEWEREWTELLKLASSEPRTHFSKNG
240 250 260 270 280 290
190 200 210 220 230
pF1KB3 LQ-----------YNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYL
:.::::.:.::: .::::::.:..: :::. .: :::. :::::
NP_001 GTGGGVDNSEDPVYESLEEFHVFVLAHILRRPIVVVADTMLRD-SGGEAFAPIPFGGIYL
300 310 320 330 340 350
240 250 260 270 280 290
pF1KB3 PLHWPAQECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDP
::. : ..:. :.::.::. :: ::...
NP_001 PLEVPPNRCHCSPLVLAYDQAHFSALVSMEQRDQQREQGMPVSQESARRSLGWGQSHQKG
360 370 380 390 400 410
>>XP_016857340 (OMIM: 611748) PREDICTED: OTU domain-cont (714 aa)
initn: 618 init1: 181 opt: 344 Z-score: 297.0 bits: 65.6 E(85289): 8.3e-10
Smith-Waterman score: 638; 33.0% identity (57.9% similar) in 430 aa overlap (56-456:14-405)
30 40 50 60 70 80
pF1KB3 PEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKLNW
. .:: .:.. ::.... ..::. .:::
XP_016 MPICAFQLPDLTVYNEDFRSFIERDLIEQSMLVALEQAGRLNW
10 20 30 40
90 100 110 120 130 140
pF1KB3 CREV----RKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTL-KETDTRNFKF
: ..:. : :.::::::.::.: ::: .: ::.:::::.. . : .. . .:
XP_016 WVSVDPTSQRLLPLATTGDGNCLLHAASLGMWGFHDRDLMLRKALYALMEKGVEKEALKR
50 60 70 80 90 100
150 160 170 180
pF1KB3 RWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTPM--ARSGLQ-----------
::. . ..:. :.:: : .:. ::..:::.::.. : . .: .
XP_016 RWRWQ--QTQQNKESGLVYTEDEWQKEWNELIKLASSEPRMHLGTNGANCGGVESSEEPV
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB3 YNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYP
:.::::.:.::: ..:::::.:..: :::. .: :::. :::::::. ::..:.: :
XP_016 YESLEEFHVFVLAHVLRRPIVVVADTMLRD-SGGEAFAPIPFGGIYLPLEVPASQCHRSP
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB3 IVLGYDSHHFVPLVTL--KDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKE
.::.::. :: ::.. :.. : ..::.. . .. : .:: .::
XP_016 LVLAYDQAHFSALVSMEQKENTKEQAVIPLTDSE---YKLLPLHFAVDPG----------
230 240 250 260
310 320 330 340 350 360
pF1KB3 YLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYK--KWQENSEQG
.::. : :. .: . : :..: .:. : : :: :
XP_016 ---------KGWEWGKDDSDNV-RLASVILSLEVKL-----HLL-HSYMNVKWIPLS---
270 280 290 300
370 380 390 400 410 420
pF1KB3 RREGHAQNPM-EPSVPQLSLMDVKCETPNCPFF--MSVNTQPLCHECSERRQKNQNKLPK
. :: :. .: : : : ::. ::... .: ..:..:.. :
XP_016 ---SDAQAPLAQPESPTASAGDEPRSTPESGDSDKESVGSSSTSNEGGRRKEKSKRDREK
310 320 330 340 350 360
430 440 450 460 470
pF1KB3 ----LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAM
.: . : : .::.. . . : . . ::
XP_016 DKKRADSVANKLGSFGKTLGSKLKKNMGGLMHSKGSKPGGVGTGLGGSSGTETLEKKKKN
370 380 390 400 410 420
480 490 500 510 520 530
pF1KB3 KCRSPGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGIC
XP_016 SLKSWKGGKEEAAGDGPVSEKPPAESVGNGGSKYSQEVMQSLSILRTAMQGEGKFIFVGT
430 440 450 460 470 480
790 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 19:36:08 2016 done: Sat Nov 5 19:36:10 2016
Total Scan time: 13.430 Total Display time: 0.220
Function used was FASTA [36.3.4 Apr, 2011]