Result of FASTA (omim) for pF1KB3222
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3222, 979 aa
  1>>>pF1KB3222 979 - 979 aa - 979 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3808+/-0.000447; mu= 21.2352+/- 0.028
 mean_var=79.9443+/-16.548, 0's: 0 Z-trim(111.2): 189  B-trim: 205 in 1/51
 Lambda= 0.143443
 statistics sampled from 19571 (19774) to 19571 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.595), E-opt: 0.2 (0.232), width:  16
 Scan time: 13.080

The best scores are:                                      opt bits E(85289)
NP_001120933 (OMIM: 120100,191900,606416,607115) N ( 979) 6616 1379.9       0
NP_001120934 (OMIM: 120100,191900,606416,607115) N ( 979) 6180 1289.7       0
XP_016855672 (OMIM: 120100,191900,606416,607115) P ( 979) 6180 1289.7       0
NP_001073289 (OMIM: 120100,191900,606416,607115) N (1036) 5990 1250.4       0
XP_016855670 (OMIM: 120100,191900,606416,607115) P (1036) 5990 1250.4       0
XP_016855671 (OMIM: 120100,191900,606416,607115) P (1036) 5990 1250.4       0
XP_011542350 (OMIM: 120100,191900,606416,607115) P (1036) 5990 1250.4       0
NP_004886 (OMIM: 120100,191900,606416,607115) NACH (1036) 5990 1250.4       0
NP_001230062 (OMIM: 120100,191900,606416,607115) N (1034) 5977 1247.7       0
XP_011542355 (OMIM: 120100,191900,606416,607115) P ( 922) 5570 1163.4       0
XP_016855673 (OMIM: 120100,191900,606416,607115) P ( 922) 5367 1121.4       0
NP_899632 (OMIM: 120100,191900,606416,607115) NACH ( 922) 5367 1121.4       0
XP_011542357 (OMIM: 120100,191900,606416,607115) P ( 865) 5236 1094.3       0
XP_016882951 (OMIM: 609648,611762) PREDICTED: NACH (1004) 1790 381.2 1.5e-104
XP_011525784 (OMIM: 609648,611762) PREDICTED: NACH ( 948) 1776 378.3 1.1e-103
NP_001264058 (OMIM: 609648,611762) NACHT, LRR and  (1004) 1776 378.3 1.1e-103
XP_016882950 (OMIM: 609648,611762) PREDICTED: NACH (1005) 1776 378.3 1.1e-103
XP_011525782 (OMIM: 609648,611762) PREDICTED: NACH (1005) 1776 378.3 1.1e-103
XP_011525781 (OMIM: 609648,611762) PREDICTED: NACH (1005) 1776 378.3 1.1e-103
XP_016882949 (OMIM: 609648,611762) PREDICTED: NACH (1061) 1776 378.3 1.2e-103
NP_653288 (OMIM: 609648,611762) NACHT, LRR and PYD (1061) 1776 378.3 1.2e-103
NP_001264055 (OMIM: 609648,611762) NACHT, LRR and  (1062) 1776 378.3 1.2e-103
XP_016882955 (OMIM: 609648,611762) PREDICTED: NACH ( 923) 1710 364.6 1.3e-99
XP_016882952 (OMIM: 609648,611762) PREDICTED: NACH ( 923) 1710 364.6 1.3e-99
XP_016882956 (OMIM: 609648,611762) PREDICTED: NACH ( 923) 1710 364.6 1.3e-99
XP_016882954 (OMIM: 609648,611762) PREDICTED: NACH ( 923) 1710 364.6 1.3e-99
XP_016882953 (OMIM: 609648,611762) PREDICTED: NACH ( 923) 1710 364.6 1.3e-99
XP_011518346 (OMIM: 609665) PREDICTED: NACHT, LRR  (1052) 1313 282.5   8e-75
NP_789792 (OMIM: 609665) NACHT, LRR and PYD domain (1093) 1313 282.5 8.3e-75
XP_016881834 (OMIM: 609645) PREDICTED: NACHT, LRR  ( 937) 1166 252.0 1.1e-65
NP_604393 (OMIM: 609645) NACHT, LRR and PYD domain ( 994) 1155 249.8 5.4e-65
XP_016881833 (OMIM: 609645) PREDICTED: NACHT, LRR  ( 938) 1134 245.4   1e-63
NP_789791 (OMIM: 609662) NACHT, LRR and PYD domain ( 655) 1097 237.6 1.6e-61
XP_011518345 (OMIM: 609662) PREDICTED: NACHT, LRR  ( 655) 1097 237.6 1.6e-61
NP_001303929 (OMIM: 609659) NACHT, LRR and PYD dom (1029) 1042 226.4   6e-58
NP_789781 (OMIM: 609659) NACHT, LRR and PYD domain (1048) 1042 226.4 6.1e-58
XP_011518233 (OMIM: 609650) PREDICTED: NACHT, LRR  ( 703)  985 214.5 1.6e-54
XP_016872741 (OMIM: 609650) PREDICTED: NACHT, LRR  ( 771)  985 214.5 1.7e-54
NP_001263629 (OMIM: 609650) NACHT, LRR and PYD dom ( 891)  985 214.6 1.9e-54
NP_612202 (OMIM: 609650) NACHT, LRR and PYD domain ( 892)  985 214.6 1.9e-54
NP_001028225 (OMIM: 606579,606636,615225) NACHT, L (1375)  976 212.8 9.8e-54
NP_127500 (OMIM: 606579,606636,615225) NACHT, LRR  (1399)  976 212.8 9.9e-54
NP_055737 (OMIM: 606579,606636,615225) NACHT, LRR  (1429)  976 212.9   1e-53
NP_127499 (OMIM: 606579,606636,615225) NACHT, LRR  (1443)  976 212.9   1e-53
NP_127497 (OMIM: 606579,606636,615225) NACHT, LRR  (1473)  976 212.9   1e-53
XP_016872742 (OMIM: 609650) PREDICTED: NACHT, LRR  ( 730)  912 199.4 5.8e-50
NP_996611 (OMIM: 231090,609661) NACHT, LRR and PYD ( 980)  838 184.2   3e-45
XP_011524903 (OMIM: 231090,609661) PREDICTED: NACH (1008)  838 184.2   3e-45
NP_631915 (OMIM: 231090,609661) NACHT, LRR and PYD (1009)  838 184.2   3e-45
XP_006723139 (OMIM: 231090,609661) PREDICTED: NACH (1037)  838 184.2 3.1e-45


>>NP_001120933 (OMIM: 120100,191900,606416,607115) NACHT  (979 aa)
 initn: 6616 init1: 6616 opt: 6616  Z-score: 7395.7  bits: 1379.9 E(85289):    0
Smith-Waterman score: 6616; 100.0% identity (100.0% similar) in 979 aa overlap (1-979:1-979)

               10        20        30        40        50        60
pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVNSGLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVNSGLT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA
              910       920       930       940       950       960

              970         
pF1KB3 LETLQEEKPELTVVFEPSW
       :::::::::::::::::::
NP_001 LETLQEEKPELTVVFEPSW
              970         

>>NP_001120934 (OMIM: 120100,191900,606416,607115) NACHT  (979 aa)
 initn: 6180 init1: 6180 opt: 6180  Z-score: 6908.1  bits: 1289.7 E(85289):    0
Smith-Waterman score: 6180; 93.8% identity (96.7% similar) in 979 aa overlap (1-979:1-979)

               10        20        30        40        50        60
pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
           :.   :  .  :::..:.:.:::::::.::: :.:.::  :.:  ::...:::  :
NP_001 GRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSC
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVNSGLT
        :.  :: :.. :::....:..: ...::::: :. .::   :.  :::.:: :::::::
NP_001 CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA
              910       920       930       940       950       960

              970         
pF1KB3 LETLQEEKPELTVVFEPSW
       :::::::::::::::::::
NP_001 LETLQEEKPELTVVFEPSW
              970         

>>XP_016855672 (OMIM: 120100,191900,606416,607115) PREDI  (979 aa)
 initn: 6180 init1: 6180 opt: 6180  Z-score: 6908.1  bits: 1289.7 E(85289):    0
Smith-Waterman score: 6180; 93.8% identity (96.7% similar) in 979 aa overlap (1-979:1-979)

               10        20        30        40        50        60
pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
           :.   :  .  :::..:.:.:::::::.::: :.:.::  :.:  ::...:::  :
XP_016 GRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSC
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVNSGLT
        :.  :: :.. :::....:..: ...::::: :. .::   :.  :::.:: :::::::
XP_016 CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA
              910       920       930       940       950       960

              970         
pF1KB3 LETLQEEKPELTVVFEPSW
       :::::::::::::::::::
XP_016 LETLQEEKPELTVVFEPSW
              970         

>>NP_001073289 (OMIM: 120100,191900,606416,607115) NACHT  (1036 aa)
 initn: 5990 init1: 5990 opt: 5990  Z-score: 6695.2  bits: 1250.4 E(85289):    0
Smith-Waterman score: 6331; 94.4% identity (94.4% similar) in 1011 aa overlap (1-954:1-1011)

               10        20        30        40        50        60
pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
              730       740       750       760       770       780

              790       800       810       820       830          
pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLV-----
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
NP_001 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLT
              790       800       810       820       830       840

                                                             840   
pF1KB3 ----------------------------------------------------NSGLTSVC
                                                           ::::::::
NP_001 SACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVC
              850       860       870       880       890       900

           850       860       870       880       890       900   
pF1KB3 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD
              910       920       930       940       950       960

           910       920       930       940       950       960   
pF1KB3 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
NP_001 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET
              970       980       990      1000      1010      1020

           970         
pF1KB3 LQEEKPELTVVFEPSW
                       
NP_001 LQEEKPELTVVFEPSW
             1030      

>>XP_016855670 (OMIM: 120100,191900,606416,607115) PREDI  (1036 aa)
 initn: 5990 init1: 5990 opt: 5990  Z-score: 6695.2  bits: 1250.4 E(85289):    0
Smith-Waterman score: 6331; 94.4% identity (94.4% similar) in 1011 aa overlap (1-954:1-1011)

               10        20        30        40        50        60
pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
              730       740       750       760       770       780

              790       800       810       820       830          
pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLV-----
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
XP_016 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLT
              790       800       810       820       830       840

                                                             840   
pF1KB3 ----------------------------------------------------NSGLTSVC
                                                           ::::::::
XP_016 SACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVC
              850       860       870       880       890       900

           850       860       870       880       890       900   
pF1KB3 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD
              910       920       930       940       950       960

           910       920       930       940       950       960   
pF1KB3 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
XP_016 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET
              970       980       990      1000      1010      1020

           970         
pF1KB3 LQEEKPELTVVFEPSW
                       
XP_016 LQEEKPELTVVFEPSW
             1030      

>>XP_016855671 (OMIM: 120100,191900,606416,607115) PREDI  (1036 aa)
 initn: 5990 init1: 5990 opt: 5990  Z-score: 6695.2  bits: 1250.4 E(85289):    0
Smith-Waterman score: 6331; 94.4% identity (94.4% similar) in 1011 aa overlap (1-954:1-1011)

               10        20        30        40        50        60
pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
              730       740       750       760       770       780

              790       800       810       820       830          
pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLV-----
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
XP_016 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLT
              790       800       810       820       830       840

                                                             840   
pF1KB3 ----------------------------------------------------NSGLTSVC
                                                           ::::::::
XP_016 SACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVC
              850       860       870       880       890       900

           850       860       870       880       890       900   
pF1KB3 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD
              910       920       930       940       950       960

           910       920       930       940       950       960   
pF1KB3 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
XP_016 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET
              970       980       990      1000      1010      1020

           970         
pF1KB3 LQEEKPELTVVFEPSW
                       
XP_016 LQEEKPELTVVFEPSW
             1030      

>>XP_011542350 (OMIM: 120100,191900,606416,607115) PREDI  (1036 aa)
 initn: 5990 init1: 5990 opt: 5990  Z-score: 6695.2  bits: 1250.4 E(85289):    0
Smith-Waterman score: 6331; 94.4% identity (94.4% similar) in 1011 aa overlap (1-954:1-1011)

               10        20        30        40        50        60
pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
              730       740       750       760       770       780

              790       800       810       820       830          
pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLV-----
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
XP_011 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLT
              790       800       810       820       830       840

                                                             840   
pF1KB3 ----------------------------------------------------NSGLTSVC
                                                           ::::::::
XP_011 SACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVC
              850       860       870       880       890       900

           850       860       870       880       890       900   
pF1KB3 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD
              910       920       930       940       950       960

           910       920       930       940       950       960   
pF1KB3 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
XP_011 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET
              970       980       990      1000      1010      1020

           970         
pF1KB3 LQEEKPELTVVFEPSW
                       
XP_011 LQEEKPELTVVFEPSW
             1030      

>>NP_004886 (OMIM: 120100,191900,606416,607115) NACHT, L  (1036 aa)
 initn: 5990 init1: 5990 opt: 5990  Z-score: 6695.2  bits: 1250.4 E(85289):    0
Smith-Waterman score: 6331; 94.4% identity (94.4% similar) in 1011 aa overlap (1-954:1-1011)

               10        20        30        40        50        60
pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
              730       740       750       760       770       780

              790       800       810       820       830          
pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLV-----
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
NP_004 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLT
              790       800       810       820       830       840

                                                             840   
pF1KB3 ----------------------------------------------------NSGLTSVC
                                                           ::::::::
NP_004 SACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVC
              850       860       870       880       890       900

           850       860       870       880       890       900   
pF1KB3 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD
              910       920       930       940       950       960

           910       920       930       940       950       960   
pF1KB3 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
NP_004 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET
              970       980       990      1000      1010      1020

           970         
pF1KB3 LQEEKPELTVVFEPSW
                       
NP_004 LQEEKPELTVVFEPSW
             1030      

>>NP_001230062 (OMIM: 120100,191900,606416,607115) NACHT  (1034 aa)
 initn: 5977 init1: 5977 opt: 5977  Z-score: 6680.7  bits: 1247.7 E(85289):    0
Smith-Waterman score: 6318; 94.4% identity (94.4% similar) in 1009 aa overlap (3-954:1-1009)

               10        20        30        40        50        60
pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001   MASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
                 10        20        30        40        50        

               70        80        90       100       110       120
pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
       60        70        80        90       100       110        

              130       140       150       160       170       180
pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
      120       130       140       150       160       170        

              190       200       210       220       230       240
pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
      180       190       200       210       220       230        

              250       260       270       280       290       300
pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
      240       250       260       270       280       290        

              310       320       330       340       350       360
pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
      300       310       320       330       340       350        

              370       380       390       400       410       420
pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
      360       370       380       390       400       410        

              430       440       450       460       470       480
pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
      420       430       440       450       460       470        

              490       500       510       520       530       540
pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
      480       490       500       510       520       530        

              550       560       570       580       590       600
pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
      540       550       560       570       580       590        

              610       620       630       640       650       660
pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
      600       610       620       630       640       650        

              670       680       690       700       710       720
pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
      660       670       680       690       700       710        

              730       740       750       760       770       780
pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
      720       730       740       750       760       770        

              790       800       810       820       830          
pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLV-----
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
NP_001 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLT
      780       790       800       810       820       830        

                                                             840   
pF1KB3 ----------------------------------------------------NSGLTSVC
                                                           ::::::::
NP_001 SACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVC
      840       850       860       870       880       890        

           850       860       870       880       890       900   
pF1KB3 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD
      900       910       920       930       940       950        

           910       920       930       940       950       960   
pF1KB3 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
NP_001 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET
      960       970       980       990      1000      1010        

           970         
pF1KB3 LQEEKPELTVVFEPSW
                       
NP_001 LQEEKPELTVVFEPSW
     1020      1030    

>>XP_011542355 (OMIM: 120100,191900,606416,607115) PREDI  (922 aa)
 initn: 5570 init1: 5570 opt: 5570  Z-score: 6226.2  bits: 1163.4 E(85289):    0
Smith-Waterman score: 6096; 94.2% identity (94.2% similar) in 979 aa overlap (1-979:1-922)

               10        20        30        40        50        60
pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_011 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWL---
              730       740       750       760       770          

              790       800       810       820       830       840
pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVNSGLT
                                                             ::::::
XP_011 ------------------------------------------------------VNSGLT
                                                             780   

              850       860       870       880       890       900
pF1KB3 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC
           790       800       810       820       830       840   

              910       920       930       940       950       960
pF1KB3 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA
           850       860       870       880       890       900   

              970         
pF1KB3 LETLQEEKPELTVVFEPSW
       :::::::::::::::::::
XP_011 LETLQEEKPELTVVFEPSW
           910       920  




979 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 12:33:12 2016 done: Thu Nov  3 12:33:14 2016
 Total Scan time: 13.080 Total Display time:  0.370

Function used was FASTA [36.3.4 Apr, 2011]
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