FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3222, 979 aa 1>>>pF1KB3222 979 - 979 aa - 979 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3808+/-0.000447; mu= 21.2352+/- 0.028 mean_var=79.9443+/-16.548, 0's: 0 Z-trim(111.2): 189 B-trim: 205 in 1/51 Lambda= 0.143443 statistics sampled from 19571 (19774) to 19571 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.595), E-opt: 0.2 (0.232), width: 16 Scan time: 13.080 The best scores are: opt bits E(85289) NP_001120933 (OMIM: 120100,191900,606416,607115) N ( 979) 6616 1379.9 0 NP_001120934 (OMIM: 120100,191900,606416,607115) N ( 979) 6180 1289.7 0 XP_016855672 (OMIM: 120100,191900,606416,607115) P ( 979) 6180 1289.7 0 NP_001073289 (OMIM: 120100,191900,606416,607115) N (1036) 5990 1250.4 0 XP_016855670 (OMIM: 120100,191900,606416,607115) P (1036) 5990 1250.4 0 XP_016855671 (OMIM: 120100,191900,606416,607115) P (1036) 5990 1250.4 0 XP_011542350 (OMIM: 120100,191900,606416,607115) P (1036) 5990 1250.4 0 NP_004886 (OMIM: 120100,191900,606416,607115) NACH (1036) 5990 1250.4 0 NP_001230062 (OMIM: 120100,191900,606416,607115) N (1034) 5977 1247.7 0 XP_011542355 (OMIM: 120100,191900,606416,607115) P ( 922) 5570 1163.4 0 XP_016855673 (OMIM: 120100,191900,606416,607115) P ( 922) 5367 1121.4 0 NP_899632 (OMIM: 120100,191900,606416,607115) NACH ( 922) 5367 1121.4 0 XP_011542357 (OMIM: 120100,191900,606416,607115) P ( 865) 5236 1094.3 0 XP_016882951 (OMIM: 609648,611762) PREDICTED: NACH (1004) 1790 381.2 1.5e-104 XP_011525784 (OMIM: 609648,611762) PREDICTED: NACH ( 948) 1776 378.3 1.1e-103 NP_001264058 (OMIM: 609648,611762) NACHT, LRR and (1004) 1776 378.3 1.1e-103 XP_016882950 (OMIM: 609648,611762) PREDICTED: NACH (1005) 1776 378.3 1.1e-103 XP_011525782 (OMIM: 609648,611762) PREDICTED: NACH (1005) 1776 378.3 1.1e-103 XP_011525781 (OMIM: 609648,611762) PREDICTED: NACH (1005) 1776 378.3 1.1e-103 XP_016882949 (OMIM: 609648,611762) PREDICTED: NACH (1061) 1776 378.3 1.2e-103 NP_653288 (OMIM: 609648,611762) NACHT, LRR and PYD (1061) 1776 378.3 1.2e-103 NP_001264055 (OMIM: 609648,611762) NACHT, LRR and (1062) 1776 378.3 1.2e-103 XP_016882955 (OMIM: 609648,611762) PREDICTED: NACH ( 923) 1710 364.6 1.3e-99 XP_016882952 (OMIM: 609648,611762) PREDICTED: NACH ( 923) 1710 364.6 1.3e-99 XP_016882956 (OMIM: 609648,611762) PREDICTED: NACH ( 923) 1710 364.6 1.3e-99 XP_016882954 (OMIM: 609648,611762) PREDICTED: NACH ( 923) 1710 364.6 1.3e-99 XP_016882953 (OMIM: 609648,611762) PREDICTED: NACH ( 923) 1710 364.6 1.3e-99 XP_011518346 (OMIM: 609665) PREDICTED: NACHT, LRR (1052) 1313 282.5 8e-75 NP_789792 (OMIM: 609665) NACHT, LRR and PYD domain (1093) 1313 282.5 8.3e-75 XP_016881834 (OMIM: 609645) PREDICTED: NACHT, LRR ( 937) 1166 252.0 1.1e-65 NP_604393 (OMIM: 609645) NACHT, LRR and PYD domain ( 994) 1155 249.8 5.4e-65 XP_016881833 (OMIM: 609645) PREDICTED: NACHT, LRR ( 938) 1134 245.4 1e-63 NP_789791 (OMIM: 609662) NACHT, LRR and PYD domain ( 655) 1097 237.6 1.6e-61 XP_011518345 (OMIM: 609662) PREDICTED: NACHT, LRR ( 655) 1097 237.6 1.6e-61 NP_001303929 (OMIM: 609659) NACHT, LRR and PYD dom (1029) 1042 226.4 6e-58 NP_789781 (OMIM: 609659) NACHT, LRR and PYD domain (1048) 1042 226.4 6.1e-58 XP_011518233 (OMIM: 609650) PREDICTED: NACHT, LRR ( 703) 985 214.5 1.6e-54 XP_016872741 (OMIM: 609650) PREDICTED: NACHT, LRR ( 771) 985 214.5 1.7e-54 NP_001263629 (OMIM: 609650) NACHT, LRR and PYD dom ( 891) 985 214.6 1.9e-54 NP_612202 (OMIM: 609650) NACHT, LRR and PYD domain ( 892) 985 214.6 1.9e-54 NP_001028225 (OMIM: 606579,606636,615225) NACHT, L (1375) 976 212.8 9.8e-54 NP_127500 (OMIM: 606579,606636,615225) NACHT, LRR (1399) 976 212.8 9.9e-54 NP_055737 (OMIM: 606579,606636,615225) NACHT, LRR (1429) 976 212.9 1e-53 NP_127499 (OMIM: 606579,606636,615225) NACHT, LRR (1443) 976 212.9 1e-53 NP_127497 (OMIM: 606579,606636,615225) NACHT, LRR (1473) 976 212.9 1e-53 XP_016872742 (OMIM: 609650) PREDICTED: NACHT, LRR ( 730) 912 199.4 5.8e-50 NP_996611 (OMIM: 231090,609661) NACHT, LRR and PYD ( 980) 838 184.2 3e-45 XP_011524903 (OMIM: 231090,609661) PREDICTED: NACH (1008) 838 184.2 3e-45 NP_631915 (OMIM: 231090,609661) NACHT, LRR and PYD (1009) 838 184.2 3e-45 XP_006723139 (OMIM: 231090,609661) PREDICTED: NACH (1037) 838 184.2 3.1e-45 >>NP_001120933 (OMIM: 120100,191900,606416,607115) NACHT (979 aa) initn: 6616 init1: 6616 opt: 6616 Z-score: 7395.7 bits: 1379.9 E(85289): 0 Smith-Waterman score: 6616; 100.0% identity (100.0% similar) in 979 aa overlap (1-979:1-979) 10 20 30 40 50 60 pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVNSGLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVNSGLT 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA 910 920 930 940 950 960 970 pF1KB3 LETLQEEKPELTVVFEPSW ::::::::::::::::::: NP_001 LETLQEEKPELTVVFEPSW 970 >>NP_001120934 (OMIM: 120100,191900,606416,607115) NACHT (979 aa) initn: 6180 init1: 6180 opt: 6180 Z-score: 6908.1 bits: 1289.7 E(85289): 0 Smith-Waterman score: 6180; 93.8% identity (96.7% similar) in 979 aa overlap (1-979:1-979) 10 20 30 40 50 60 pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC :. : . :::..:.:.:::::::.::: :.:.:: :.: ::...::: : NP_001 GRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVNSGLT :. :: :.. :::....:..: ...::::: :. .:: :. :::.:: ::::::: NP_001 CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLT 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA 910 920 930 940 950 960 970 pF1KB3 LETLQEEKPELTVVFEPSW ::::::::::::::::::: NP_001 LETLQEEKPELTVVFEPSW 970 >>XP_016855672 (OMIM: 120100,191900,606416,607115) PREDI (979 aa) initn: 6180 init1: 6180 opt: 6180 Z-score: 6908.1 bits: 1289.7 E(85289): 0 Smith-Waterman score: 6180; 93.8% identity (96.7% similar) in 979 aa overlap (1-979:1-979) 10 20 30 40 50 60 pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC :. : . :::..:.:.:::::::.::: :.:.:: :.: ::...::: : XP_016 GRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVNSGLT :. :: :.. :::....:..: ...::::: :. .:: :. :::.:: ::::::: XP_016 CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLT 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA 910 920 930 940 950 960 970 pF1KB3 LETLQEEKPELTVVFEPSW ::::::::::::::::::: XP_016 LETLQEEKPELTVVFEPSW 970 >>NP_001073289 (OMIM: 120100,191900,606416,607115) NACHT (1036 aa) initn: 5990 init1: 5990 opt: 5990 Z-score: 6695.2 bits: 1250.4 E(85289): 0 Smith-Waterman score: 6331; 94.4% identity (94.4% similar) in 1011 aa overlap (1-954:1-1011) 10 20 30 40 50 60 pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC 730 740 750 760 770 780 790 800 810 820 830 pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLV----- ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLT 790 800 810 820 830 840 840 pF1KB3 ----------------------------------------------------NSGLTSVC :::::::: NP_001 SACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVC 850 860 870 880 890 900 850 860 870 880 890 900 pF1KB3 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD 910 920 930 940 950 960 910 920 930 940 950 960 pF1KB3 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET 970 980 990 1000 1010 1020 970 pF1KB3 LQEEKPELTVVFEPSW NP_001 LQEEKPELTVVFEPSW 1030 >>XP_016855670 (OMIM: 120100,191900,606416,607115) PREDI (1036 aa) initn: 5990 init1: 5990 opt: 5990 Z-score: 6695.2 bits: 1250.4 E(85289): 0 Smith-Waterman score: 6331; 94.4% identity (94.4% similar) in 1011 aa overlap (1-954:1-1011) 10 20 30 40 50 60 pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC 730 740 750 760 770 780 790 800 810 820 830 pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLV----- ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLT 790 800 810 820 830 840 840 pF1KB3 ----------------------------------------------------NSGLTSVC :::::::: XP_016 SACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVC 850 860 870 880 890 900 850 860 870 880 890 900 pF1KB3 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD 910 920 930 940 950 960 910 920 930 940 950 960 pF1KB3 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET 970 980 990 1000 1010 1020 970 pF1KB3 LQEEKPELTVVFEPSW XP_016 LQEEKPELTVVFEPSW 1030 >>XP_016855671 (OMIM: 120100,191900,606416,607115) PREDI (1036 aa) initn: 5990 init1: 5990 opt: 5990 Z-score: 6695.2 bits: 1250.4 E(85289): 0 Smith-Waterman score: 6331; 94.4% identity (94.4% similar) in 1011 aa overlap (1-954:1-1011) 10 20 30 40 50 60 pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC 730 740 750 760 770 780 790 800 810 820 830 pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLV----- ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLT 790 800 810 820 830 840 840 pF1KB3 ----------------------------------------------------NSGLTSVC :::::::: XP_016 SACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVC 850 860 870 880 890 900 850 860 870 880 890 900 pF1KB3 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD 910 920 930 940 950 960 910 920 930 940 950 960 pF1KB3 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET 970 980 990 1000 1010 1020 970 pF1KB3 LQEEKPELTVVFEPSW XP_016 LQEEKPELTVVFEPSW 1030 >>XP_011542350 (OMIM: 120100,191900,606416,607115) PREDI (1036 aa) initn: 5990 init1: 5990 opt: 5990 Z-score: 6695.2 bits: 1250.4 E(85289): 0 Smith-Waterman score: 6331; 94.4% identity (94.4% similar) in 1011 aa overlap (1-954:1-1011) 10 20 30 40 50 60 pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC 730 740 750 760 770 780 790 800 810 820 830 pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLV----- ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLT 790 800 810 820 830 840 840 pF1KB3 ----------------------------------------------------NSGLTSVC :::::::: XP_011 SACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVC 850 860 870 880 890 900 850 860 870 880 890 900 pF1KB3 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD 910 920 930 940 950 960 910 920 930 940 950 960 pF1KB3 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET 970 980 990 1000 1010 1020 970 pF1KB3 LQEEKPELTVVFEPSW XP_011 LQEEKPELTVVFEPSW 1030 >>NP_004886 (OMIM: 120100,191900,606416,607115) NACHT, L (1036 aa) initn: 5990 init1: 5990 opt: 5990 Z-score: 6695.2 bits: 1250.4 E(85289): 0 Smith-Waterman score: 6331; 94.4% identity (94.4% similar) in 1011 aa overlap (1-954:1-1011) 10 20 30 40 50 60 pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC 730 740 750 760 770 780 790 800 810 820 830 pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLV----- ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLT 790 800 810 820 830 840 840 pF1KB3 ----------------------------------------------------NSGLTSVC :::::::: NP_004 SACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVC 850 860 870 880 890 900 850 860 870 880 890 900 pF1KB3 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD 910 920 930 940 950 960 910 920 930 940 950 960 pF1KB3 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET 970 980 990 1000 1010 1020 970 pF1KB3 LQEEKPELTVVFEPSW NP_004 LQEEKPELTVVFEPSW 1030 >>NP_001230062 (OMIM: 120100,191900,606416,607115) NACHT (1034 aa) initn: 5977 init1: 5977 opt: 5977 Z-score: 6680.7 bits: 1247.7 E(85289): 0 Smith-Waterman score: 6318; 94.4% identity (94.4% similar) in 1009 aa overlap (3-954:1-1009) 10 20 30 40 50 60 pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC 720 730 740 750 760 770 790 800 810 820 830 pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLV----- ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLT 780 790 800 810 820 830 840 pF1KB3 ----------------------------------------------------NSGLTSVC :::::::: NP_001 SACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVC 840 850 860 870 880 890 850 860 870 880 890 900 pF1KB3 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD 900 910 920 930 940 950 910 920 930 940 950 960 pF1KB3 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALET 960 970 980 990 1000 1010 970 pF1KB3 LQEEKPELTVVFEPSW NP_001 LQEEKPELTVVFEPSW 1020 1030 >>XP_011542355 (OMIM: 120100,191900,606416,607115) PREDI (922 aa) initn: 5570 init1: 5570 opt: 5570 Z-score: 6226.2 bits: 1163.4 E(85289): 0 Smith-Waterman score: 6096; 94.2% identity (94.2% similar) in 979 aa overlap (1-979:1-922) 10 20 30 40 50 60 pF1KB3 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRC ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWL--- 730 740 750 760 770 790 800 810 820 830 840 pF1KB3 GLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVNSGLT :::::: XP_011 ------------------------------------------------------VNSGLT 780 850 860 870 880 890 900 pF1KB3 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHC 790 800 810 820 830 840 910 920 930 940 950 960 pF1KB3 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSA 850 860 870 880 890 900 970 pF1KB3 LETLQEEKPELTVVFEPSW ::::::::::::::::::: XP_011 LETLQEEKPELTVVFEPSW 910 920 979 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:33:12 2016 done: Thu Nov 3 12:33:14 2016 Total Scan time: 13.080 Total Display time: 0.370 Function used was FASTA [36.3.4 Apr, 2011]