FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3226, 620 aa 1>>>pF1KB3226 620 - 620 aa - 620 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.0240+/-0.000437; mu= -20.2022+/- 0.027 mean_var=553.2214+/-115.197, 0's: 0 Z-trim(124.5): 37 B-trim: 1529 in 1/58 Lambda= 0.054529 statistics sampled from 46186 (46223) to 46186 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.542), width: 16 Scan time: 11.880 The best scores are: opt bits E(85289) XP_011536311 (OMIM: 602582) PREDICTED: E3 ubiquiti ( 620) 4378 359.2 2.5e-98 NP_004407 (OMIM: 602582) E3 ubiquitin-protein liga ( 620) 4378 359.2 2.5e-98 NP_001287656 (OMIM: 616110) E3 ubiquitin-protein l ( 513) 1871 161.9 5e-39 XP_006718546 (OMIM: 616110) PREDICTED: E3 ubiquiti ( 513) 1871 161.9 5e-39 NP_055992 (OMIM: 616110) E3 ubiquitin-protein liga ( 619) 1871 162.0 5.8e-39 XP_005250189 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1808 157.0 1.8e-37 NP_001096064 (OMIM: 613141) probable E3 ubiquitin- ( 622) 1808 157.0 1.8e-37 XP_011514077 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1808 157.0 1.8e-37 NP_065943 (OMIM: 613141) probable E3 ubiquitin-pro ( 622) 1808 157.0 1.8e-37 XP_011514076 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1808 157.0 1.8e-37 NP_001096065 (OMIM: 613141) probable E3 ubiquitin- ( 622) 1808 157.0 1.8e-37 XP_016867213 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1808 157.0 1.8e-37 XP_011514075 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1808 157.0 1.8e-37 XP_016867214 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1808 157.0 1.8e-37 XP_005250188 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1808 157.0 1.8e-37 XP_011514074 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1808 157.0 1.8e-37 XP_016867212 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1808 157.0 1.8e-37 XP_016867216 (OMIM: 613141) PREDICTED: probable E3 ( 575) 1197 108.9 5e-23 NP_001096066 (OMIM: 613141) probable E3 ubiquitin- ( 575) 1197 108.9 5e-23 XP_016867215 (OMIM: 613141) PREDICTED: probable E3 ( 575) 1197 108.9 5e-23 XP_016867219 (OMIM: 613141) PREDICTED: probable E3 ( 414) 687 68.7 4.7e-11 XP_016867218 (OMIM: 613141) PREDICTED: probable E3 ( 419) 687 68.7 4.7e-11 XP_016867217 (OMIM: 613141) PREDICTED: probable E3 ( 568) 567 59.3 4.1e-08 NP_612144 (OMIM: 613143) E3 ubiquitin-protein liga ( 740) 498 54.0 2.2e-06 XP_011536324 (OMIM: 613142) PREDICTED: probable E3 ( 347) 409 46.7 0.00016 NP_848597 (OMIM: 613142) probable E3 ubiquitin-pro ( 347) 409 46.7 0.00016 NP_001273175 (OMIM: 613142) probable E3 ubiquitin- ( 347) 409 46.7 0.00016 XP_005268760 (OMIM: 613142) PREDICTED: probable E3 ( 347) 409 46.7 0.00016 NP_001273174 (OMIM: 613142) probable E3 ubiquitin- ( 350) 409 46.7 0.00016 XP_005268757 (OMIM: 613142) PREDICTED: probable E3 ( 350) 409 46.7 0.00016 XP_005268754 (OMIM: 613142) PREDICTED: probable E3 ( 350) 409 46.7 0.00016 XP_005268755 (OMIM: 613142) PREDICTED: probable E3 ( 350) 409 46.7 0.00016 >>XP_011536311 (OMIM: 602582) PREDICTED: E3 ubiquitin-pr (620 aa) initn: 4378 init1: 4378 opt: 4378 Z-score: 1886.4 bits: 359.2 E(85289): 2.5e-98 Smith-Waterman score: 4378; 100.0% identity (100.0% similar) in 620 aa overlap (1-620:1-620) 10 20 30 40 50 60 pF1KB3 MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDARGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDARGSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 VLGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAWTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAWTA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 YDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 RTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 PPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQKVKNPPDEDCTICMERLVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQKVKNPPDEDCTICMERLVT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 ASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 TQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 NEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASY 550 560 570 580 590 600 610 620 pF1KB3 LDNVLAELTAQGVSEAAAKA :::::::::::::::::::: XP_011 LDNVLAELTAQGVSEAAAKA 610 620 >>NP_004407 (OMIM: 602582) E3 ubiquitin-protein ligase D (620 aa) initn: 4378 init1: 4378 opt: 4378 Z-score: 1886.4 bits: 359.2 E(85289): 2.5e-98 Smith-Waterman score: 4378; 100.0% identity (100.0% similar) in 620 aa overlap (1-620:1-620) 10 20 30 40 50 60 pF1KB3 MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDARGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDARGSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 VLGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAWTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VLGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAWTA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 YDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 RTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 PPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQKVKNPPDEDCTICMERLVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQKVKNPPDEDCTICMERLVT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 ASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 TQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 NEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASY 550 560 570 580 590 600 610 620 pF1KB3 LDNVLAELTAQGVSEAAAKA :::::::::::::::::::: NP_004 LDNVLAELTAQGVSEAAAKA 610 620 >>NP_001287656 (OMIM: 616110) E3 ubiquitin-protein ligas (513 aa) initn: 2163 init1: 1130 opt: 1871 Z-score: 821.6 bits: 161.9 E(85289): 5e-39 Smith-Waterman score: 2186; 62.4% identity (83.1% similar) in 510 aa overlap (123-615:1-505) 100 110 120 130 140 150 pF1KB3 RRNFYDPSSAPGKGIVWEWENDGGAWTAYDMDICITIQNAYEKQHPWLDLSSLGFCYLIY :.. ::::.::::::::.::.:.:: :.: NP_001 MEVGITIQHAYEKQHPWIDLTSIGFSYVID 10 20 30 160 170 180 190 200 pF1KB3 FNSMSQMNRQTRRRRRLRRRLDLAYPLTVGSIPKSQSWPV--GASSG---QPCSCQQCLL ::.:.:.::::.:.::.:::::: ::...:..::.::::: : ... .:::: ::.: NP_001 FNTMGQINRQTQRQRRVRRRLDLIYPMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVL 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB3 VNSTRAA-----SNAI-LASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAA : :..:: .. . : :.. :: . :: ::. :: . ..:. : : .: NP_001 VMSVKAAVVNGSTGPLQLPVTRKNMPPPGVVKLPPLPGS--GAKPLDSTGTIRGP-LKTA 100 110 120 130 140 270 280 290 300 310 pF1KB3 PAAGPAEPAP--PPGAPPRSPGAPGGARTP-GQ---NNLNRPGPQRTTSVSARASIPPGV :. . : : :. ::..: : . :. .::: . :: . ...:. : :: NP_001 PSQVIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRLAIAQSRVLIASGV 150 160 170 180 190 200 320 330 340 350 360 370 pF1KB3 PALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVP :..:::::::..::.:::::.::::. :::::::::: :: .:::::::::..: .::: NP_001 PTVPVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVS 210 220 230 240 250 260 380 390 400 410 420 430 pF1KB3 GVCRKTKKKHLKKSKNPEDVVRRYMQKVKNPPDEDCTICMERLVTASGYEGVLRHKGVRP .. ::: ::. ::.:.::.:...:.:::..:::::::::::::.. :::.: . :.: NP_001 NTSRKTTKKQAKKGKTPEEVLKKYLQKVRHPPDEDCTICMERLTAPSGYKGP--QPTVKP 270 280 290 300 310 320 440 450 460 470 480 490 pF1KB3 ELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHS .:::.:.::::.::. ::::::.::::::::::::::.::: :::::::::::.:::::: NP_001 DLVGKLSRCGHVYHIYCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHS 330 340 350 360 370 380 500 510 520 530 540 550 pF1KB3 LPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAW ::: :: .::::.:.:: ::::::::::::.:.:::::::::::..:::::::.::..:: NP_001 LPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAW 390 400 410 420 430 440 560 570 580 590 600 610 pF1KB3 ERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSE .:::::.::::.::::::::.:::.::::::::::::::::::.:::::::::.:::.:: NP_001 DRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISE 450 460 470 480 490 500 620 pF1KB3 AAAKA NP_001 DSTAQEKD 510 >>XP_006718546 (OMIM: 616110) PREDICTED: E3 ubiquitin-pr (513 aa) initn: 2163 init1: 1130 opt: 1871 Z-score: 821.6 bits: 161.9 E(85289): 5e-39 Smith-Waterman score: 2186; 62.4% identity (83.1% similar) in 510 aa overlap (123-615:1-505) 100 110 120 130 140 150 pF1KB3 RRNFYDPSSAPGKGIVWEWENDGGAWTAYDMDICITIQNAYEKQHPWLDLSSLGFCYLIY :.. ::::.::::::::.::.:.:: :.: XP_006 MEVGITIQHAYEKQHPWIDLTSIGFSYVID 10 20 30 160 170 180 190 200 pF1KB3 FNSMSQMNRQTRRRRRLRRRLDLAYPLTVGSIPKSQSWPV--GASSG---QPCSCQQCLL ::.:.:.::::.:.::.:::::: ::...:..::.::::: : ... .:::: ::.: XP_006 FNTMGQINRQTQRQRRVRRRLDLIYPMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVL 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB3 VNSTRAA-----SNAI-LASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAA : :..:: .. . : :.. :: . :: ::. :: . ..:. : : .: XP_006 VMSVKAAVVNGSTGPLQLPVTRKNMPPPGVVKLPPLPGS--GAKPLDSTGTIRGP-LKTA 100 110 120 130 140 270 280 290 300 310 pF1KB3 PAAGPAEPAP--PPGAPPRSPGAPGGARTP-GQ---NNLNRPGPQRTTSVSARASIPPGV :. . : : :. ::..: : . :. .::: . :: . ...:. : :: XP_006 PSQVIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRLAIAQSRVLIASGV 150 160 170 180 190 200 320 330 340 350 360 370 pF1KB3 PALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVP :..:::::::..::.:::::.::::. :::::::::: :: .:::::::::..: .::: XP_006 PTVPVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVS 210 220 230 240 250 260 380 390 400 410 420 430 pF1KB3 GVCRKTKKKHLKKSKNPEDVVRRYMQKVKNPPDEDCTICMERLVTASGYEGVLRHKGVRP .. ::: ::. ::.:.::.:...:.:::..:::::::::::::.. :::.: . :.: XP_006 NTSRKTTKKQAKKGKTPEEVLKKYLQKVRHPPDEDCTICMERLTAPSGYKGP--QPTVKP 270 280 290 300 310 320 440 450 460 470 480 490 pF1KB3 ELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHS .:::.:.::::.::. ::::::.::::::::::::::.::: :::::::::::.:::::: XP_006 DLVGKLSRCGHVYHIYCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHS 330 340 350 360 370 380 500 510 520 530 540 550 pF1KB3 LPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAW ::: :: .::::.:.:: ::::::::::::.:.:::::::::::..:::::::.::..:: XP_006 LPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAW 390 400 410 420 430 440 560 570 580 590 600 610 pF1KB3 ERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSE .:::::.::::.::::::::.:::.::::::::::::::::::.:::::::::.:::.:: XP_006 DRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISE 450 460 470 480 490 500 620 pF1KB3 AAAKA XP_006 DSTAQEKD 510 >>NP_055992 (OMIM: 616110) E3 ubiquitin-protein ligase D (619 aa) initn: 2559 init1: 1130 opt: 1871 Z-score: 820.5 bits: 162.0 E(85289): 5.8e-39 Smith-Waterman score: 2758; 64.9% identity (84.4% similar) in 610 aa overlap (25-615:7-611) 10 20 30 40 50 pF1KB3 MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDAR--G ::::::::::.:::::. .: :::: :.. : : NP_055 MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEAVVRAGPRAGG 10 20 30 40 60 70 80 90 100 110 pF1KB3 SVVLGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAW ::::::::..:.:::::::::.::::::::.::::::.::::::::::.:::::::.:.: NP_055 SVVLGQVDSRLAPYIIDLQSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGSW 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB3 TAYDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYP : :::.. ::::.::::::::.::.:.:: :.: ::.:.:.::::.:.::.:::::: :: NP_055 TPYDMEVGITIQHAYEKQHPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIYP 110 120 130 140 150 160 180 190 200 210 220 pF1KB3 LTVGSIPKSQSWPVG---ASSG--QPCSCQQCLLVNSTRAA-----SNAI-LASQRRKAP ...:..::.:::::. :.: .:::: ::.:: :..:: .. . : :.. : NP_055 MVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVLVMSVKAAVVNGSTGPLQLPVTRKNMP 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB3 PAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAP--PPGAPPRSPGAPGG : . :: ::. :: . ..:. : : .::. . : : :. ::..: : NP_055 PPGVVKLPPLPGS--GAKPLDSTGTIRGP-LKTAPSQVIRRQASSMPTGTTMGSPASPPG 230 240 250 260 270 290 300 310 320 330 340 pF1KB3 ARTP-GQ---NNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILL . :. .::: . :: . ...:. : :::..:::::::..::.:::::.::::. NP_055 PNSKTGRVALATLNRTNLQRLAIAQSRVLIASGVPTVPVKNLNGSSPVNPALAGITGILM 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB3 CAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQ :::::::::: :: .:::::::::..: .::: .. ::: ::. ::.:.::.:...:.: NP_055 SAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTSRKTTKKQAKKGKTPEEVLKKYLQ 340 350 360 370 380 390 410 420 430 440 450 460 pF1KB3 KVKNPPDEDCTICMERLVTASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGN ::..:::::::::::::.. :::.: . :.:.:::.:.::::.::. ::::::.::: NP_055 KVRHPPDEDCTICMERLTAPSGYKGP--QPTVKPDLVGKLSRCGHVYHIYCLVAMYNNGN 400 410 420 430 440 450 470 480 490 500 510 520 pF1KB3 KDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHP :::::::::::.::: :::::::::::.::::::::: :: .::::.:.:: :::::::: NP_055 KDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHP 460 470 480 490 500 510 530 540 550 560 570 580 pF1KB3 NPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIH ::::.:.:::::::::::..:::::::.::..::.:::::.::::.::::::::.:::.: NP_055 NPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVH 520 530 540 550 560 570 590 600 610 620 pF1KB3 HKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSEAAAKA :::::::::::::::::.:::::::::.:::.:: NP_055 HKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQEKD 580 590 600 610 >>XP_005250189 (OMIM: 613141) PREDICTED: probable E3 ubi (622 aa) initn: 1732 init1: 1108 opt: 1808 Z-score: 793.7 bits: 157.0 E(85289): 1.8e-37 Smith-Waterman score: 1810; 48.2% identity (67.6% similar) in 620 aa overlap (23-615:17-616) 10 20 30 40 50 pF1KB3 MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIEN--VLKEDAR- : :.:::: . . :.::.:::: ::. : .. : XP_005 MAMAPSPSLVQVYTSPAAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRF 10 20 30 40 50 60 70 80 90 100 110 pF1KB3 --GSVV----LGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEW ::.. :::.: .:.:::::: : :::::::::: :::... ::::.:.:::: XP_005 GLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEW 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 ENDGGAWTAYDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRR .: :.::::. ..: ... . . .::. ::. : . ... .: :. . : .:: XP_005 LSDDGSWTAYEASVCDYLEQQVARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 RLDLAYPLTVGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPP . ::.:. : ... : :::.::: . : .:. :. :: : XP_005 QAGPPYPVTTIIAPPGHT-------GVACSCHQCLSGSRTGPVSGRYRHSMTNL--PAYP 180 190 200 210 220 240 250 260 270 280 pF1KB3 LPPPPPPG-----GPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGA .: :: : :.: . ...:: .:: . .. :: : : :. XP_005 VPQHPPHRTASVFGTHQAFAPYNKPSLSGAR--SAPRLNTTNAW---GAAPPSLGSQPLY 230 240 250 260 270 280 290 300 310 320 330 pF1KB3 RTPGQNNLNRPGPQR-----TTSVSARASIP------PG-VPALPVKNLNGTGPVHPALA :. .:.. :::. .:: .. ::.: :: ::: .. . :. ::: XP_005 RS----SLSHLGPQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQMPKPSRVQQALA 290 300 310 320 330 340 350 360 370 380 390 pF1KB3 GMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSK-NPE :::..:. : ::::::.:::.: ::.:. : .: . . . : : . .:: XP_005 GMTSVLMSAIGLPVCLSRAPQPT--SPPASRLASKSHGSVKRLRKMSVKGATPKPEPEPE 340 350 360 370 380 390 400 410 420 430 440 450 pF1KB3 DVVRRYMQKVKNPPDEDCTICMERLVTASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCL .:.. : ...: :::::: ::::.: ::::: : :.. ::.: .:.: .::::: XP_005 QVIKNYTEELKVPPDEDCIICMEKLSTASGYSDVTDSKAIGSLAVGHLTKCSHAFHLLCL 400 410 420 430 440 450 460 470 480 490 500 510 pF1KB3 VAMYSNGNKDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPT .::: :::::::::::.::.:::::::::: :::: . :::: : :: :::.:: XP_005 LAMYCNGNKDGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYSIPH 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB3 GIQGPEHPNPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESD :::::::::::: ::::::::.::::.: .:::::.:: .::.::::::.:::.::::.: XP_005 GIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTGETD 520 530 540 550 560 570 580 590 600 610 620 pF1KB3 TVVWNEIHHKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSEAAAKA ::::::::::::. :.::::::: .::.::::::.::::.: XP_005 TVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ 580 590 600 610 620 >>NP_001096064 (OMIM: 613141) probable E3 ubiquitin-prot (622 aa) initn: 1732 init1: 1108 opt: 1808 Z-score: 793.7 bits: 157.0 E(85289): 1.8e-37 Smith-Waterman score: 1810; 48.2% identity (67.6% similar) in 620 aa overlap (23-615:17-616) 10 20 30 40 50 pF1KB3 MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIEN--VLKEDAR- : :.:::: . . :.::.:::: ::. : .. : NP_001 MAMAPSPSLVQVYTSPAAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRF 10 20 30 40 50 60 70 80 90 100 110 pF1KB3 --GSVV----LGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEW ::.. :::.: .:.:::::: : :::::::::: :::... ::::.:.:::: NP_001 GLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEW 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 ENDGGAWTAYDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRR .: :.::::. ..: ... . . .::. ::. : . ... .: :. . : .:: NP_001 LSDDGSWTAYEASVCDYLEQQVARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 RLDLAYPLTVGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPP . ::.:. : ... : :::.::: . : .:. :. :: : NP_001 QAGPPYPVTTIIAPPGHT-------GVACSCHQCLSGSRTGPVSGRYRHSMTNL--PAYP 180 190 200 210 220 240 250 260 270 280 pF1KB3 LPPPPPPG-----GPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGA .: :: : :.: . ...:: .:: . .. :: : : :. NP_001 VPQHPPHRTASVFGTHQAFAPYNKPSLSGAR--SAPRLNTTNAW---GAAPPSLGSQPLY 230 240 250 260 270 280 290 300 310 320 330 pF1KB3 RTPGQNNLNRPGPQR-----TTSVSARASIP------PG-VPALPVKNLNGTGPVHPALA :. .:.. :::. .:: .. ::.: :: ::: .. . :. ::: NP_001 RS----SLSHLGPQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQMPKPSRVQQALA 290 300 310 320 330 340 350 360 370 380 390 pF1KB3 GMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSK-NPE :::..:. : ::::::.:::.: ::.:. : .: . . . : : . .:: NP_001 GMTSVLMSAIGLPVCLSRAPQPT--SPPASRLASKSHGSVKRLRKMSVKGATPKPEPEPE 340 350 360 370 380 390 400 410 420 430 440 450 pF1KB3 DVVRRYMQKVKNPPDEDCTICMERLVTASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCL .:.. : ...: :::::: ::::.: ::::: : :.. ::.: .:.: .::::: NP_001 QVIKNYTEELKVPPDEDCIICMEKLSTASGYSDVTDSKAIGSLAVGHLTKCSHAFHLLCL 400 410 420 430 440 450 460 470 480 490 500 510 pF1KB3 VAMYSNGNKDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPT .::: :::::::::::.::.:::::::::: :::: . :::: : :: :::.:: NP_001 LAMYCNGNKDGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYSIPH 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB3 GIQGPEHPNPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESD :::::::::::: ::::::::.::::.: .:::::.:: .::.::::::.:::.::::.: NP_001 GIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTGETD 520 530 540 550 560 570 580 590 600 610 620 pF1KB3 TVVWNEIHHKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSEAAAKA ::::::::::::. :.::::::: .::.::::::.::::.: NP_001 TVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ 580 590 600 610 620 >>XP_011514077 (OMIM: 613141) PREDICTED: probable E3 ubi (622 aa) initn: 1732 init1: 1108 opt: 1808 Z-score: 793.7 bits: 157.0 E(85289): 1.8e-37 Smith-Waterman score: 1810; 48.2% identity (67.6% similar) in 620 aa overlap (23-615:17-616) 10 20 30 40 50 pF1KB3 MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIEN--VLKEDAR- : :.:::: . . :.::.:::: ::. : .. : XP_011 MAMAPSPSLVQVYTSPAAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRF 10 20 30 40 50 60 70 80 90 100 110 pF1KB3 --GSVV----LGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEW ::.. :::.: .:.:::::: : :::::::::: :::... ::::.:.:::: XP_011 GLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEW 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 ENDGGAWTAYDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRR .: :.::::. ..: ... . . .::. ::. : . ... .: :. . : .:: XP_011 LSDDGSWTAYEASVCDYLEQQVARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 RLDLAYPLTVGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPP . ::.:. : ... : :::.::: . : .:. :. :: : XP_011 QAGPPYPVTTIIAPPGHT-------GVACSCHQCLSGSRTGPVSGRYRHSMTNL--PAYP 180 190 200 210 220 240 250 260 270 280 pF1KB3 LPPPPPPG-----GPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGA .: :: : :.: . ...:: .:: . .. :: : : :. XP_011 VPQHPPHRTASVFGTHQAFAPYNKPSLSGAR--SAPRLNTTNAW---GAAPPSLGSQPLY 230 240 250 260 270 280 290 300 310 320 330 pF1KB3 RTPGQNNLNRPGPQR-----TTSVSARASIP------PG-VPALPVKNLNGTGPVHPALA :. .:.. :::. .:: .. ::.: :: ::: .. . :. ::: XP_011 RS----SLSHLGPQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQMPKPSRVQQALA 290 300 310 320 330 340 350 360 370 380 390 pF1KB3 GMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSK-NPE :::..:. : ::::::.:::.: ::.:. : .: . . . : : . .:: XP_011 GMTSVLMSAIGLPVCLSRAPQPT--SPPASRLASKSHGSVKRLRKMSVKGATPKPEPEPE 340 350 360 370 380 390 400 410 420 430 440 450 pF1KB3 DVVRRYMQKVKNPPDEDCTICMERLVTASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCL .:.. : ...: :::::: ::::.: ::::: : :.. ::.: .:.: .::::: XP_011 QVIKNYTEELKVPPDEDCIICMEKLSTASGYSDVTDSKAIGSLAVGHLTKCSHAFHLLCL 400 410 420 430 440 450 460 470 480 490 500 510 pF1KB3 VAMYSNGNKDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPT .::: :::::::::::.::.:::::::::: :::: . :::: : :: :::.:: XP_011 LAMYCNGNKDGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYSIPH 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB3 GIQGPEHPNPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESD :::::::::::: ::::::::.::::.: .:::::.:: .::.::::::.:::.::::.: XP_011 GIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTGETD 520 530 540 550 560 570 580 590 600 610 620 pF1KB3 TVVWNEIHHKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSEAAAKA ::::::::::::. :.::::::: .::.::::::.::::.: XP_011 TVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ 580 590 600 610 620 >>NP_065943 (OMIM: 613141) probable E3 ubiquitin-protein (622 aa) initn: 1732 init1: 1108 opt: 1808 Z-score: 793.7 bits: 157.0 E(85289): 1.8e-37 Smith-Waterman score: 1810; 48.2% identity (67.6% similar) in 620 aa overlap (23-615:17-616) 10 20 30 40 50 pF1KB3 MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIEN--VLKEDAR- : :.:::: . . :.::.:::: ::. : .. : NP_065 MAMAPSPSLVQVYTSPAAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRF 10 20 30 40 50 60 70 80 90 100 110 pF1KB3 --GSVV----LGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEW ::.. :::.: .:.:::::: : :::::::::: :::... ::::.:.:::: NP_065 GLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEW 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 ENDGGAWTAYDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRR .: :.::::. ..: ... . . .::. ::. : . ... .: :. . : .:: NP_065 LSDDGSWTAYEASVCDYLEQQVARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 RLDLAYPLTVGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPP . ::.:. : ... : :::.::: . : .:. :. :: : NP_065 QAGPPYPVTTIIAPPGHT-------GVACSCHQCLSGSRTGPVSGRYRHSMTNL--PAYP 180 190 200 210 220 240 250 260 270 280 pF1KB3 LPPPPPPG-----GPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGA .: :: : :.: . ...:: .:: . .. :: : : :. NP_065 VPQHPPHRTASVFGTHQAFAPYNKPSLSGAR--SAPRLNTTNAW---GAAPPSLGSQPLY 230 240 250 260 270 280 290 300 310 320 330 pF1KB3 RTPGQNNLNRPGPQR-----TTSVSARASIP------PG-VPALPVKNLNGTGPVHPALA :. .:.. :::. .:: .. ::.: :: ::: .. . :. ::: NP_065 RS----SLSHLGPQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQMPKPSRVQQALA 290 300 310 320 330 340 350 360 370 380 390 pF1KB3 GMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSK-NPE :::..:. : ::::::.:::.: ::.:. : .: . . . : : . .:: NP_065 GMTSVLMSAIGLPVCLSRAPQPT--SPPASRLASKSHGSVKRLRKMSVKGATPKPEPEPE 340 350 360 370 380 390 400 410 420 430 440 450 pF1KB3 DVVRRYMQKVKNPPDEDCTICMERLVTASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCL .:.. : ...: :::::: ::::.: ::::: : :.. ::.: .:.: .::::: NP_065 QVIKNYTEELKVPPDEDCIICMEKLSTASGYSDVTDSKAIGSLAVGHLTKCSHAFHLLCL 400 410 420 430 440 450 460 470 480 490 500 510 pF1KB3 VAMYSNGNKDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPT .::: :::::::::::.::.:::::::::: :::: . :::: : :: :::.:: NP_065 LAMYCNGNKDGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYSIPH 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB3 GIQGPEHPNPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESD :::::::::::: ::::::::.::::.: .:::::.:: .::.::::::.:::.::::.: NP_065 GIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTGETD 520 530 540 550 560 570 580 590 600 610 620 pF1KB3 TVVWNEIHHKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSEAAAKA ::::::::::::. :.::::::: .::.::::::.::::.: NP_065 TVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ 580 590 600 610 620 >>XP_011514076 (OMIM: 613141) PREDICTED: probable E3 ubi (622 aa) initn: 1732 init1: 1108 opt: 1808 Z-score: 793.7 bits: 157.0 E(85289): 1.8e-37 Smith-Waterman score: 1810; 48.2% identity (67.6% similar) in 620 aa overlap (23-615:17-616) 10 20 30 40 50 pF1KB3 MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIEN--VLKEDAR- : :.:::: . . :.::.:::: ::. : .. : XP_011 MAMAPSPSLVQVYTSPAAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRF 10 20 30 40 50 60 70 80 90 100 110 pF1KB3 --GSVV----LGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEW ::.. :::.: .:.:::::: : :::::::::: :::... ::::.:.:::: XP_011 GLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEW 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 ENDGGAWTAYDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRR .: :.::::. ..: ... . . .::. ::. : . ... .: :. . : .:: XP_011 LSDDGSWTAYEASVCDYLEQQVARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 RLDLAYPLTVGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPP . ::.:. : ... : :::.::: . : .:. :. :: : XP_011 QAGPPYPVTTIIAPPGHT-------GVACSCHQCLSGSRTGPVSGRYRHSMTNL--PAYP 180 190 200 210 220 240 250 260 270 280 pF1KB3 LPPPPPPG-----GPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGA .: :: : :.: . ...:: .:: . .. :: : : :. XP_011 VPQHPPHRTASVFGTHQAFAPYNKPSLSGAR--SAPRLNTTNAW---GAAPPSLGSQPLY 230 240 250 260 270 280 290 300 310 320 330 pF1KB3 RTPGQNNLNRPGPQR-----TTSVSARASIP------PG-VPALPVKNLNGTGPVHPALA :. .:.. :::. .:: .. ::.: :: ::: .. . :. ::: XP_011 RS----SLSHLGPQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQMPKPSRVQQALA 290 300 310 320 330 340 350 360 370 380 390 pF1KB3 GMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSK-NPE :::..:. : ::::::.:::.: ::.:. : .: . . . : : . .:: XP_011 GMTSVLMSAIGLPVCLSRAPQPT--SPPASRLASKSHGSVKRLRKMSVKGATPKPEPEPE 340 350 360 370 380 390 400 410 420 430 440 450 pF1KB3 DVVRRYMQKVKNPPDEDCTICMERLVTASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCL .:.. : ...: :::::: ::::.: ::::: : :.. ::.: .:.: .::::: XP_011 QVIKNYTEELKVPPDEDCIICMEKLSTASGYSDVTDSKAIGSLAVGHLTKCSHAFHLLCL 400 410 420 430 440 450 460 470 480 490 500 510 pF1KB3 VAMYSNGNKDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPT .::: :::::::::::.::.:::::::::: :::: . :::: : :: :::.:: XP_011 LAMYCNGNKDGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYSIPH 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB3 GIQGPEHPNPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESD :::::::::::: ::::::::.::::.: .:::::.:: .::.::::::.:::.::::.: XP_011 GIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTGETD 520 530 540 550 560 570 580 590 600 610 620 pF1KB3 TVVWNEIHHKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSEAAAKA ::::::::::::. :.::::::: .::.::::::.::::.: XP_011 TVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ 580 590 600 610 620 620 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:35:19 2016 done: Thu Nov 3 12:35:20 2016 Total Scan time: 11.880 Total Display time: 0.150 Function used was FASTA [36.3.4 Apr, 2011]