FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3230, 629 aa 1>>>pF1KB3230 629 - 629 aa - 629 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6080+/-0.000556; mu= 7.9966+/- 0.035 mean_var=173.6320+/-37.293, 0's: 0 Z-trim(111.8): 249 B-trim: 410 in 1/55 Lambda= 0.097333 statistics sampled from 20177 (20483) to 20177 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.24), width: 16 Scan time: 10.330 The best scores are: opt bits E(85289) XP_016885026 (OMIM: 189960,300000,300552) PREDICTE ( 629) 4243 609.3 1.3e-173 XP_016885028 (OMIM: 189960,300000,300552) PREDICTE ( 629) 4243 609.3 1.3e-173 XP_016885027 (OMIM: 189960,300000,300552) PREDICTE ( 629) 4243 609.3 1.3e-173 NP_150631 (OMIM: 189960,300000,300552) E3 ubiquiti ( 629) 4243 609.3 1.3e-173 XP_016885025 (OMIM: 189960,300000,300552) PREDICTE ( 667) 2978 431.7 4e-120 NP_000372 (OMIM: 189960,300000,300552) E3 ubiquiti ( 667) 2978 431.7 4e-120 NP_150632 (OMIM: 189960,300000,300552) E3 ubiquiti ( 667) 2978 431.7 4e-120 NP_001180206 (OMIM: 189960,300000,300552) E3 ubiqu ( 667) 2978 431.7 4e-120 NP_001092094 (OMIM: 189960,300000,300552) E3 ubiqu ( 667) 2978 431.7 4e-120 XP_016885024 (OMIM: 189960,300000,300552) PREDICTE ( 680) 2777 403.5 1.3e-111 XP_006724555 (OMIM: 189960,300000,300552) PREDICTE ( 718) 2777 403.5 1.3e-111 XP_011543829 (OMIM: 189960,300000,300552) PREDICTE ( 718) 2777 403.5 1.3e-111 XP_005274593 (OMIM: 189960,300000,300552) PREDICTE ( 718) 2777 403.5 1.3e-111 XP_011543827 (OMIM: 189960,300000,300552) PREDICTE ( 718) 2777 403.5 1.3e-111 XP_011543828 (OMIM: 189960,300000,300552) PREDICTE ( 718) 2777 403.5 1.3e-111 XP_005274594 (OMIM: 189960,300000,300552) PREDICTE ( 718) 2777 403.5 1.3e-111 XP_016885023 (OMIM: 189960,300000,300552) PREDICTE ( 718) 2777 403.5 1.3e-111 NP_001180209 (OMIM: 189960,300000,300552) E3 ubiqu ( 451) 2593 377.5 5.7e-104 XP_016884728 (OMIM: 300204,300928) PREDICTED: prob ( 685) 2310 337.9 7.1e-92 NP_438112 (OMIM: 300204,300928) probable E3 ubiqui ( 705) 2310 337.9 7.3e-92 XP_016885029 (OMIM: 189960,300000,300552) PREDICTE ( 552) 2156 316.2 2e-85 NP_001180210 (OMIM: 189960,300000,300552) E3 ubiqu ( 228) 1472 219.8 8.4e-57 XP_016885031 (OMIM: 189960,300000,300552) PREDICTE ( 489) 1328 199.9 1.8e-50 NP_001180208 (OMIM: 189960,300000,300552) E3 ubiqu ( 489) 1328 199.9 1.8e-50 XP_016885030 (OMIM: 189960,300000,300552) PREDICTE ( 540) 1279 193.0 2.3e-48 NP_001180207 (OMIM: 189960,300000,300552) E3 ubiqu ( 540) 1279 193.0 2.3e-48 XP_005262119 (OMIM: 300204,300928) PREDICTED: prob ( 715) 1223 185.3 6.5e-46 NP_036348 (OMIM: 300204,300928) probable E3 ubiqui ( 735) 1223 185.3 6.7e-46 XP_016870676 (OMIM: 609829) PREDICTED: FSD1-like p ( 317) 469 79.1 2.7e-14 XP_016870674 (OMIM: 609829) PREDICTED: FSD1-like p ( 362) 463 78.3 5.3e-14 XP_016870672 (OMIM: 609829) PREDICTED: FSD1-like p ( 498) 458 77.7 1.1e-13 NP_001274121 (OMIM: 609829) FSD1-like protein isof ( 497) 457 77.6 1.2e-13 NP_001274120 (OMIM: 609829) FSD1-like protein isof ( 508) 457 77.6 1.2e-13 NP_001317668 (OMIM: 609829) FSD1-like protein isof ( 509) 457 77.6 1.2e-13 NP_001138785 (OMIM: 609829) FSD1-like protein isof ( 530) 452 76.9 2e-13 XP_011517380 (OMIM: 609829) PREDICTED: FSD1-like p ( 543) 452 76.9 2.1e-13 XP_016870671 (OMIM: 609829) PREDICTED: FSD1-like p ( 529) 451 76.7 2.2e-13 XP_005252311 (OMIM: 609829) PREDICTED: FSD1-like p ( 541) 451 76.8 2.3e-13 XP_011517381 (OMIM: 609829) PREDICTED: FSD1-like p ( 542) 451 76.8 2.3e-13 XP_011517379 (OMIM: 609829) PREDICTED: FSD1-like p ( 547) 451 76.8 2.3e-13 XP_011517382 (OMIM: 609829) PREDICTED: FSD1-like p ( 322) 357 63.4 1.5e-09 XP_016870675 (OMIM: 609829) PREDICTED: FSD1-like p ( 322) 357 63.4 1.5e-09 XP_005252317 (OMIM: 609829) PREDICTED: FSD1-like p ( 384) 357 63.4 1.7e-09 XP_016870673 (OMIM: 609829) PREDICTED: FSD1-like p ( 384) 357 63.4 1.7e-09 XP_011517383 (OMIM: 609829) PREDICTED: FSD1-like p ( 311) 345 61.7 4.6e-09 NP_077309 (OMIM: 609828) fibronectin type III and ( 496) 346 62.0 5.9e-09 NP_001229732 (OMIM: 613595) butyrophilin subfamily ( 374) 310 56.8 1.6e-07 NP_115935 (OMIM: 606474) tripartite motif-containi ( 400) 310 56.8 1.7e-07 NP_001723 (OMIM: 601610) butyrophilin subfamily 1 ( 526) 312 57.2 1.7e-07 XP_005249397 (OMIM: 601610) PREDICTED: butyrophili ( 626) 312 57.3 1.9e-07 >>XP_016885026 (OMIM: 189960,300000,300552) PREDICTED: E (629 aa) initn: 4243 init1: 4243 opt: 4243 Z-score: 3237.9 bits: 609.3 E(85289): 1.3e-173 Smith-Waterman score: 4243; 100.0% identity (100.0% similar) in 629 aa overlap (1-629:1-629) 10 20 30 40 50 60 pF1KB3 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 EKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 IIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITER 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 VSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 ITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 PERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 RCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVC 550 560 570 580 590 600 610 620 pF1KB3 PTFTVWNKCLTIITGLPIPDHLDCTEQLP ::::::::::::::::::::::::::::: XP_016 PTFTVWNKCLTIITGLPIPDHLDCTEQLP 610 620 >>XP_016885028 (OMIM: 189960,300000,300552) PREDICTED: E (629 aa) initn: 4243 init1: 4243 opt: 4243 Z-score: 3237.9 bits: 609.3 E(85289): 1.3e-173 Smith-Waterman score: 4243; 100.0% identity (100.0% similar) in 629 aa overlap (1-629:1-629) 10 20 30 40 50 60 pF1KB3 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 EKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 IIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITER 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 VSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 ITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 PERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 RCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVC 550 560 570 580 590 600 610 620 pF1KB3 PTFTVWNKCLTIITGLPIPDHLDCTEQLP ::::::::::::::::::::::::::::: XP_016 PTFTVWNKCLTIITGLPIPDHLDCTEQLP 610 620 >>XP_016885027 (OMIM: 189960,300000,300552) PREDICTED: E (629 aa) initn: 4243 init1: 4243 opt: 4243 Z-score: 3237.9 bits: 609.3 E(85289): 1.3e-173 Smith-Waterman score: 4243; 100.0% identity (100.0% similar) in 629 aa overlap (1-629:1-629) 10 20 30 40 50 60 pF1KB3 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 EKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 IIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITER 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 VSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 ITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 PERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 RCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVC 550 560 570 580 590 600 610 620 pF1KB3 PTFTVWNKCLTIITGLPIPDHLDCTEQLP ::::::::::::::::::::::::::::: XP_016 PTFTVWNKCLTIITGLPIPDHLDCTEQLP 610 620 >>NP_150631 (OMIM: 189960,300000,300552) E3 ubiquitin-pr (629 aa) initn: 4243 init1: 4243 opt: 4243 Z-score: 3237.9 bits: 609.3 E(85289): 1.3e-173 Smith-Waterman score: 4243; 100.0% identity (100.0% similar) in 629 aa overlap (1-629:1-629) 10 20 30 40 50 60 pF1KB3 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 EKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 EKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 IIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 IIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITER 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 VSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 VSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 ITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 ITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 YIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 PERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 PERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 RCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 RCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVC 550 560 570 580 590 600 610 620 pF1KB3 PTFTVWNKCLTIITGLPIPDHLDCTEQLP ::::::::::::::::::::::::::::: NP_150 PTFTVWNKCLTIITGLPIPDHLDCTEQLP 610 620 >>XP_016885025 (OMIM: 189960,300000,300552) PREDICTED: E (667 aa) initn: 2977 init1: 2977 opt: 2978 Z-score: 2277.5 bits: 431.7 E(85289): 4e-120 Smith-Waterman score: 4123; 94.3% identity (94.3% similar) in 661 aa overlap (7-629:7-667) 10 20 30 40 50 60 pF1KB3 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 130 140 150 160 170 180 190 200 pF1KB3 EK--------------------------------------QNLESNLTNLIKRNTELETL :: :::::::::::::::::::: XP_016 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB3 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB3 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB3 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB3 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB3 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB3 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB3 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL 610 620 630 640 650 660 pF1KB3 DCTEQLP ::::::: XP_016 DCTEQLP >>NP_000372 (OMIM: 189960,300000,300552) E3 ubiquitin-pr (667 aa) initn: 2977 init1: 2977 opt: 2978 Z-score: 2277.5 bits: 431.7 E(85289): 4e-120 Smith-Waterman score: 4123; 94.3% identity (94.3% similar) in 661 aa overlap (7-629:7-667) 10 20 30 40 50 60 pF1KB3 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 130 140 150 160 170 180 190 200 pF1KB3 EK--------------------------------------QNLESNLTNLIKRNTELETL :: :::::::::::::::::::: NP_000 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB3 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB3 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB3 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB3 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB3 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB3 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB3 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL 610 620 630 640 650 660 pF1KB3 DCTEQLP ::::::: NP_000 DCTEQLP >>NP_150632 (OMIM: 189960,300000,300552) E3 ubiquitin-pr (667 aa) initn: 2977 init1: 2977 opt: 2978 Z-score: 2277.5 bits: 431.7 E(85289): 4e-120 Smith-Waterman score: 4123; 94.3% identity (94.3% similar) in 661 aa overlap (7-629:7-667) 10 20 30 40 50 60 pF1KB3 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 130 140 150 160 170 180 190 200 pF1KB3 EK--------------------------------------QNLESNLTNLIKRNTELETL :: :::::::::::::::::::: NP_150 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB3 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB3 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB3 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB3 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB3 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB3 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB3 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL 610 620 630 640 650 660 pF1KB3 DCTEQLP ::::::: NP_150 DCTEQLP >>NP_001180206 (OMIM: 189960,300000,300552) E3 ubiquitin (667 aa) initn: 2977 init1: 2977 opt: 2978 Z-score: 2277.5 bits: 431.7 E(85289): 4e-120 Smith-Waterman score: 4123; 94.3% identity (94.3% similar) in 661 aa overlap (7-629:7-667) 10 20 30 40 50 60 pF1KB3 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 130 140 150 160 170 180 190 200 pF1KB3 EK--------------------------------------QNLESNLTNLIKRNTELETL :: :::::::::::::::::::: NP_001 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB3 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB3 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB3 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB3 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB3 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB3 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB3 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL 610 620 630 640 650 660 pF1KB3 DCTEQLP ::::::: NP_001 DCTEQLP >>NP_001092094 (OMIM: 189960,300000,300552) E3 ubiquitin (667 aa) initn: 2977 init1: 2977 opt: 2978 Z-score: 2277.5 bits: 431.7 E(85289): 4e-120 Smith-Waterman score: 4123; 94.3% identity (94.3% similar) in 661 aa overlap (7-629:7-667) 10 20 30 40 50 60 pF1KB3 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 130 140 150 160 170 180 190 200 pF1KB3 EK--------------------------------------QNLESNLTNLIKRNTELETL :: :::::::::::::::::::: NP_001 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB3 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB3 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB3 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB3 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB3 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB3 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB3 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL 610 620 630 640 650 660 pF1KB3 DCTEQLP ::::::: NP_001 DCTEQLP >>XP_016885024 (OMIM: 189960,300000,300552) PREDICTED: E (680 aa) initn: 2777 init1: 2777 opt: 2777 Z-score: 2124.9 bits: 403.5 E(85289): 1.3e-111 Smith-Waterman score: 4002; 92.3% identity (92.3% similar) in 661 aa overlap (20-629:20-680) 10 20 30 40 50 60 pF1KB3 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR ::::::::::::::::::::::::::::::::::::::::: XP_016 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 130 140 150 160 170 180 190 200 210 pF1KB3 EKQNLESNLTNLIKRNTELETLLAKLIQTCQHVE-------------------------- :::::::::::::::::::::::::::::::::: XP_016 EKQNLESNLTNLIKRNTELETLLAKLIQTCQHVETVKDQKVIGREKQQYYPRNRRKWVSN 190 200 210 220 230 240 220 230 240 pF1KB3 -------------------------VNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEG ::::::::::::::::::::::::::::::::::: XP_016 SLQARLMGRRCISRRERKLTLDVEKVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEG 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB3 KVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQ 310 320 330 340 350 360 310 320 330 340 350 360 pF1KB3 VLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDD 370 380 390 400 410 420 370 380 390 400 410 420 pF1KB3 EFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAIN 430 440 450 460 470 480 430 440 450 460 470 480 pF1KB3 QAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGS 490 500 510 520 530 540 490 500 510 520 530 540 pF1KB3 YGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVR 550 560 570 580 590 600 550 560 570 580 590 600 pF1KB3 HNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKC 610 620 630 640 650 660 610 620 pF1KB3 LTIITGLPIPDHLDCTEQLP :::::::::::::::::::: XP_016 LTIITGLPIPDHLDCTEQLP 670 680 629 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:36:01 2016 done: Thu Nov 3 12:36:02 2016 Total Scan time: 10.330 Total Display time: 0.210 Function used was FASTA [36.3.4 Apr, 2011]