FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3232, 713 aa 1>>>pF1KB3232 713 - 713 aa - 713 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.9421+/-0.000521; mu= 6.9372+/- 0.032 mean_var=301.8341+/-65.099, 0's: 0 Z-trim(115.9): 306 B-trim: 33 in 1/58 Lambda= 0.073823 statistics sampled from 26247 (26711) to 26247 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.313), width: 16 Scan time: 10.310 The best scores are: opt bits E(85289) XP_011507368 (OMIM: 605492) PREDICTED: leucine-ric ( 713) 4794 525.7 2.4e-148 NP_006329 (OMIM: 605492) leucine-rich repeat neuro ( 713) 4794 525.7 2.4e-148 XP_005244884 (OMIM: 605492) PREDICTED: leucine-ric ( 713) 4794 525.7 2.4e-148 NP_963924 (OMIM: 605492) leucine-rich repeat neuro ( 713) 4794 525.7 2.4e-148 XP_016855539 (OMIM: 605492) PREDICTED: leucine-ric ( 713) 4794 525.7 2.4e-148 NP_004961 (OMIM: 601489,615961) insulin-like growt ( 605) 450 63.0 4e-09 NP_001139478 (OMIM: 601489,615961) insulin-like gr ( 643) 450 63.0 4.1e-09 NP_001264155 (OMIM: 606667) leucine-rich repeat-co ( 883) 441 62.3 9.7e-09 NP_003658 (OMIM: 606667) leucine-rich repeat-conta ( 907) 419 59.9 5e-08 NP_612449 (OMIM: 608843) vasorin precursor [Homo s ( 673) 412 59.0 7e-08 NP_060960 (OMIM: 606666,615311) leucine-rich repea ( 951) 407 58.7 1.2e-07 NP_001333361 (OMIM: 606666,615311) leucine-rich re ( 927) 398 57.7 2.4e-07 NP_848665 (OMIM: 610462) reticulon-4 receptor-like ( 420) 387 56.1 3.4e-07 XP_016857485 (OMIM: 606653) PREDICTED: leucine-ric ( 876) 391 56.9 3.9e-07 XP_011508141 (OMIM: 606653) PREDICTED: leucine-ric ( 900) 387 56.5 5.3e-07 NP_067649 (OMIM: 606653) leucine-rich repeat-conta ( 915) 387 56.5 5.3e-07 XP_005245461 (OMIM: 606653) PREDICTED: leucine-ric ( 924) 387 56.5 5.4e-07 NP_004479 (OMIM: 173511) platelet glycoprotein V p ( 560) 378 55.3 7.8e-07 XP_011531880 (OMIM: 608868) PREDICTED: leucine-ric (1045) 371 54.9 1.9e-06 NP_075380 (OMIM: 181500,605566) reticulon-4 recept ( 473) 364 53.7 2e-06 NP_001017403 (OMIM: 606653) leucine-rich repeat-co ( 967) 365 54.2 2.8e-06 XP_011508140 (OMIM: 606653) PREDICTED: leucine-ric ( 900) 361 53.8 3.6e-06 NP_001288124 (OMIM: 609791) leucine-rich repeat an ( 614) 354 52.8 4.8e-06 XP_011520420 (OMIM: 609791) PREDICTED: leucine-ric ( 614) 354 52.8 4.8e-06 NP_001288118 (OMIM: 609791) leucine-rich repeat an ( 614) 354 52.8 4.8e-06 NP_001288126 (OMIM: 609791) leucine-rich repeat an ( 614) 354 52.8 4.8e-06 NP_001288127 (OMIM: 609791) leucine-rich repeat an ( 614) 354 52.8 4.8e-06 NP_001288128 (OMIM: 609791) leucine-rich repeat an ( 614) 354 52.8 4.8e-06 NP_001288121 (OMIM: 609791) leucine-rich repeat an ( 614) 354 52.8 4.8e-06 NP_001288123 (OMIM: 609791) leucine-rich repeat an ( 614) 354 52.8 4.8e-06 NP_001288115 (OMIM: 609791) leucine-rich repeat an ( 614) 354 52.8 4.8e-06 XP_016878171 (OMIM: 609791) PREDICTED: leucine-ric ( 614) 354 52.8 4.8e-06 NP_001288116 (OMIM: 609791) leucine-rich repeat an ( 614) 354 52.8 4.8e-06 NP_001288129 (OMIM: 609791) leucine-rich repeat an ( 614) 354 52.8 4.8e-06 NP_001288120 (OMIM: 609791) leucine-rich repeat an ( 614) 354 52.8 4.8e-06 NP_116197 (OMIM: 609791) leucine-rich repeat and i ( 620) 354 52.8 4.9e-06 XP_016874279 (OMIM: 608870) PREDICTED: leucine-ric ( 623) 354 52.8 4.9e-06 XP_011536195 (OMIM: 608870) PREDICTED: leucine-ric (1041) 354 53.1 6.6e-06 NP_001129523 (OMIM: 608870) leucine-rich repeats a (1059) 354 53.1 6.6e-06 NP_700356 (OMIM: 608870) leucine-rich repeats and (1119) 354 53.1 6.9e-06 XP_016859476 (OMIM: 610867) PREDICTED: leucine-ric ( 522) 347 51.9 7.4e-06 XP_016859475 (OMIM: 610867) PREDICTED: leucine-ric ( 522) 347 51.9 7.4e-06 NP_849161 (OMIM: 610867) leucine-rich repeat trans ( 522) 347 51.9 7.4e-06 NP_001258 (OMIM: 602178) chondroadherin precursor ( 359) 344 51.4 7.4e-06 NP_001004432 (OMIM: 609794) leucine-rich repeat an ( 593) 347 52.0 7.9e-06 XP_011522516 (OMIM: 602178) PREDICTED: chondroadhe ( 440) 344 51.5 8.3e-06 NP_001245139 (OMIM: 608015) tsukushin isoform b pr ( 353) 339 50.9 1.1e-05 NP_001305408 (OMIM: 608015) tsukushin isoform b pr ( 353) 339 50.9 1.1e-05 NP_001305407 (OMIM: 608015) tsukushin isoform b pr ( 353) 339 50.9 1.1e-05 NP_056331 (OMIM: 608015) tsukushin isoform b precu ( 353) 339 50.9 1.1e-05 >>XP_011507368 (OMIM: 605492) PREDICTED: leucine-rich re (713 aa) initn: 4794 init1: 4794 opt: 4794 Z-score: 2784.4 bits: 525.7 E(85289): 2.4e-148 Smith-Waterman score: 4794; 99.9% identity (100.0% similar) in 713 aa overlap (1-713:1-713) 10 20 30 40 50 60 pF1KB3 MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_011 MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS 670 680 690 700 710 >>NP_006329 (OMIM: 605492) leucine-rich repeat neuronal (713 aa) initn: 4794 init1: 4794 opt: 4794 Z-score: 2784.4 bits: 525.7 E(85289): 2.4e-148 Smith-Waterman score: 4794; 99.9% identity (100.0% similar) in 713 aa overlap (1-713:1-713) 10 20 30 40 50 60 pF1KB3 MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: NP_006 MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS 670 680 690 700 710 >>XP_005244884 (OMIM: 605492) PREDICTED: leucine-rich re (713 aa) initn: 4794 init1: 4794 opt: 4794 Z-score: 2784.4 bits: 525.7 E(85289): 2.4e-148 Smith-Waterman score: 4794; 99.9% identity (100.0% similar) in 713 aa overlap (1-713:1-713) 10 20 30 40 50 60 pF1KB3 MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_005 MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS 670 680 690 700 710 >>NP_963924 (OMIM: 605492) leucine-rich repeat neuronal (713 aa) initn: 4794 init1: 4794 opt: 4794 Z-score: 2784.4 bits: 525.7 E(85289): 2.4e-148 Smith-Waterman score: 4794; 99.9% identity (100.0% similar) in 713 aa overlap (1-713:1-713) 10 20 30 40 50 60 pF1KB3 MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: NP_963 MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS 670 680 690 700 710 >>XP_016855539 (OMIM: 605492) PREDICTED: leucine-rich re (713 aa) initn: 4794 init1: 4794 opt: 4794 Z-score: 2784.4 bits: 525.7 E(85289): 2.4e-148 Smith-Waterman score: 4794; 99.9% identity (100.0% similar) in 713 aa overlap (1-713:1-713) 10 20 30 40 50 60 pF1KB3 MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_016 MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVG 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGETLLPPLSQNS 670 680 690 700 710 >>NP_004961 (OMIM: 601489,615961) insulin-like growth fa (605 aa) initn: 336 init1: 336 opt: 450 Z-score: 284.8 bits: 63.0 E(85289): 4e-09 Smith-Waterman score: 450; 30.0% identity (58.6% similar) in 377 aa overlap (3-372:8-375) 10 20 30 40 pF1KB3 MRLLVAPLLLAWVA-------GATATVPVVPWHVPCPPQCACQIRPWYTPRSSYR : .: :::.::: :: .: :: :.:. : . NP_004 MALRKGGLALALLLLSWVALGPRSLEGADPGTPGEAEGPACPAACVCS----YDDDA--- 10 20 30 40 50 50 60 70 80 90 100 pF1KB3 EATTVDCNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDA . .: :.. :: .: ..:.:::.: :..:.. : . . :..: :.:. ..... NP_004 DELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB3 RDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLL . . .: .: ::::.::: : .:: .: : :..:.: :. : ::..: NP_004 EPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLW 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB3 RLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREI :.:. : : .. . :. : .:. :...::.. . : ::.:: : :. :: : NP_004 DLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAI 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB3 SDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLK . .. : :..: . : .: : :. . .:..:::..: . . : ..: :. NP_004 KANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLR 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB3 ELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALS : :.. . ..:. .. .: : .:.. .: :. . :.:. : :.:.: :..: :. NP_004 VLRLSH-NAIASLRPRTFKDLHFLEELQLGHN-RIRQLAERSFEGLGQLEVLTLDHNQLQ 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB3 ALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPV .. . .: :. ..: :: .: NP_004 EVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSG 360 370 380 390 400 410 >>NP_001139478 (OMIM: 601489,615961) insulin-like growth (643 aa) initn: 336 init1: 336 opt: 450 Z-score: 284.5 bits: 63.0 E(85289): 4.1e-09 Smith-Waterman score: 450; 30.0% identity (58.6% similar) in 377 aa overlap (3-372:46-413) 10 20 pF1KB3 MRLLVAPLLLAWVA-------GATATVPVVPW : .: :::.::: :: .: NP_001 ERRFRLCWYQAHSGRALLGPPPQASPPAGGLALALLLLSWVALGPRSLEGADPGTPGEAE 20 30 40 50 60 70 30 40 50 60 70 80 pF1KB3 HVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPALPAGTQTLLLQSNSIVRVD :: :.:. : . . .: :.. :: .: ..:.:::.: :..:.. : NP_001 GPACPAACVCS----YDDDA---DELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVP 80 90 100 110 120 90 100 110 120 130 140 pF1KB3 QSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQE . . :..: :.:. ..... . . .: .: ::::.::: : .:: .: NP_001 PAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALAS 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB3 LYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAIL : :..:.: :. : ::..: :.:. : : .. . :. : .:. :...::.. . NP_001 LGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQ 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB3 DMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKF : ::.:: : :. :: :. .. : :..: . : .: : :. . .:.. NP_001 PALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRW 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB3 LDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSF :::..: . . : ..: :. : :.. . ..:. .. .: : .:.. .: :. NP_001 LDLSHNRVAGLLEDTFPGLLGLRVLRLSH-NAIASLRPRTFKDLHFLEELQLGHN-RIRQ 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB3 IHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGT . :.:. : :.:.: :..: :. .. . .: :. ..: :: .: NP_001 LAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKL 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB3 RVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHCLPLISPRSFPPSLQVASGESMVLHC NP_001 HSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTH 430 440 450 460 470 480 >>NP_001264155 (OMIM: 606667) leucine-rich repeat-contai (883 aa) initn: 420 init1: 311 opt: 441 Z-score: 277.9 bits: 62.3 E(85289): 9.7e-09 Smith-Waterman score: 452; 30.5% identity (58.4% similar) in 370 aa overlap (3-371:9-362) 10 20 30 40 50 pF1KB3 MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVD :: :.:: ..:... : . :: .: :. : . : :: NP_001 MDTSRLGVLLSLPVLLQLATGGSSPRSGVLLR-GCPTHCHCE------PDG--RMLLRVD 10 20 30 40 50 60 70 80 90 100 110 pF1KB3 CNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFH :.:: :. .: : . :. : :. :.: .. . : : : :: :. :... : NP_001 CSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 ALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNS .: .: : :..::: .. ... .: ::: : :. :.. . : :::: .: .: :.. NP_001 GLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDD 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 NLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALE : : : . :. : :. . .. ::. : :. : :..: : : . .. .. .. NP_001 NALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFD 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 GLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNN ::.:::.:.. :.: . : :.. . .:: : . ::.: :: . : .. .:. : ::. NP_001 GLHSLETLDLNYNNLDEFPT-AIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 MEELVSI-DKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQ ... . : . .:: :: .. ..: . . ..::....: :. : : : . NP_001 ASQITEFPDLTGTANLESLT----LTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSF 300 310 320 330 340 360 370 380 390 400 410 pF1KB3 TVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPF .: . .::.. :. : : NP_001 SVCQ--KLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLD 350 360 370 380 390 400 >>NP_003658 (OMIM: 606667) leucine-rich repeat-containin (907 aa) initn: 778 init1: 297 opt: 419 Z-score: 265.1 bits: 59.9 E(85289): 5e-08 Smith-Waterman score: 444; 28.7% identity (56.4% similar) in 456 aa overlap (3-449:9-419) 10 20 30 40 50 pF1KB3 MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVD :: :.:: ..:... : . :: .: :. : . : :: NP_003 MDTSRLGVLLSLPVLLQLATGGSSPRSGVLLR-GCPTHCHCE------PDG--RMLLRVD 10 20 30 40 50 60 70 80 90 100 110 pF1KB3 CNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFH :.:: :. .: : . :. : :. :.: .. . : : : :: :. :... : NP_003 CSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 ALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNS .: .: : :..::: .. ... .: ::: : :. :.. . : :::: .: .: :.. NP_003 GLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDD 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 NLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALE : : : : :.: :: :. :....:: ....: :::. NP_003 NALTEI--------P-----------VQA-----FRSLSALQAMTLALNKIHHIPDYAFG 180 190 200 240 250 260 270 280 290 pF1KB3 GLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNN .:.:: : ...:.. . .. .. . .:. :::: : :.. : . .. .:::::... NP_003 NLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF-PTAIRTLSNLKELGFHS 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB3 MEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQT ... :: . :.:. : : . . .:: ..:. ::.:::...:: ::. : . . NP_003 -NNIRSIPEKAFVGNPSLITIHFYDNP-IQFVGRSAFQHLPELRTLTLNG-ASQITEFPD 270 280 290 300 310 320 360 370 380 390 400 pF1KB3 VESLPNLQEVGLHGNPIR------CDCVIRWANATGTRVRFIE--PQSTLCAEPPDLQRL . . ::. . : : : :. . .. ..: :. ..: . ::.. NP_003 LTGTANLESLTLTGAQISSLPQTVCNQLPNL-QVLDLSYNLLEDLPSFSVCQK---LQKI 330 340 350 360 370 410 420 430 440 450 460 pF1KB3 PVREVPFREM-TDHCLPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRL .:. . :. .: :.: :: :..: .. ..: :.. NP_003 DLRHNEIYEIKVDTFQQLLSLRS----LNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLS 380 390 400 410 420 430 470 480 490 500 510 520 pF1KB3 TPAHAGRRYRVYPEGTLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDE NP_003 SFPITGLHGLTHLKLTGNHALQSLISSENFPELKVIEMPYAYQCCAFGVCENAYKISNQW 440 450 460 470 480 490 >>NP_612449 (OMIM: 608843) vasorin precursor [Homo sapie (673 aa) initn: 371 init1: 232 opt: 412 Z-score: 262.4 bits: 59.0 E(85289): 7e-08 Smith-Waterman score: 434; 26.9% identity (51.7% similar) in 714 aa overlap (4-697:7-666) 10 20 30 40 50 pF1KB3 MRLLVAPLLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCND :. :::: . : : : :: : :. .: :: :. NP_612 MCSRVPLLLPLLLLLALG-----PGVQ---GCPSGCQCS-QPQ-----------TVFCTA 10 20 30 40 60 70 80 90 100 110 pF1KB3 LFLTAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALP :.:: .: : : . :.:. .: . .. : .: ::::::.... . :. : NP_612 RQGTTVPRDVPPDTVGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLA 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB3 QLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLL .: .: : :.: .. ...: :: :..:::..:.. .: : ::. :. ::.:.:..: : NP_612 NLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNEL 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB3 RAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQ ::. :: : .: .. :.. : :. .. ::...: :::..:..... . :. NP_612 RALPPL---RLPRLLLLDLSHNSLLA-LEPGILDTANVEALRLAGLGLQQLDEGLFSRLR 170 180 190 200 210 240 250 260 270 280 290 pF1KB3 SLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNP-LQRVGPGDFANMLHLKELGLNNME .:..:. :::: ::: ... . :: : : : . .. : :.:.. :.:: ..:. NP_612 NLHDLDVSDNQLERVPP-VIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLS 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB3 -ELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTV . . : .: .:.: : . :: .. . : .. : .. .... : ..: NP_612 LQALPGDLSGL--FPRLRLLAAARNP-FNCVCPLSWFG-PWVR----ESHVTLASPEETR 280 290 300 310 320 360 370 380 390 400 pF1KB3 ESLP--NLQEVGLHGNPIRCDCVIRWANATGTRVRFI--EPQSTLCAEPPDL--QRLPVR .: : .. :. . : ..:: .: . :: . . : :. NP_612 CHFPPKNAGRLLLELDYADFGCPATTTTATVPTTRPVVREPTALSSSLAPTWLSPTEPAT 330 340 350 360 370 380 410 420 430 440 450 460 pF1KB3 EVPFREMT--DHCLPLISPRSFPPSLQVASGESMVLHCRALAEPEPE----IYWVTPAGL :.: : :. .:.. ::: . .: . . :: :: .: . : NP_612 EAPSPPSTAPPTVGPVPQPQDCPPSTCLNGGTCHLGTRHHLACLCPEGFTGLYCESQMGQ 390 400 410 420 430 440 470 480 490 500 510 520 pF1KB3 RLTPAHAGRRYRVYPEGTLELRRVTAEEAGLYTCVAQNLVGADTKTVSV-VVGRALLQPG :. . : : .: : . ..: . . . : :.... :. .. : : : NP_612 GTRPSPTPVTPR--PPRSLTLGIEPVSPTSLRVGLQRYLQGSSVQLRSLRLTYRNLSGPD 450 460 470 480 490 500 530 540 550 560 570 580 pF1KB3 RDEGQGLELRVQETHPYHILLSWVTPPNTVSTNLTWSSASSL-RGQGATALARLPRGTHS . . . ::. . . . . . : : :. . . . . .:. : . :. : ..:: NP_612 K---RLVTLRLPASLAEYTV-TQLRPNATYSVCVMPLGPGRVPEGEEACGEAHTPPAVHS 510 520 530 540 550 560 590 600 610 620 630 640 pF1KB3 YNITRLLQATEYWACLQVAFADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLL : . . :: : : .: : : . :: . : :. : : : :.:. NP_612 -NHAPVTQAREGNLPLLIAPALAAVLLAALAAVG--AAYCVRR-GR--------AMAA-- 570 580 590 600 650 660 670 680 690 pF1KB3 LAAGLAAHLGTGQ-PRKGVGGRRPLPP---AWAFWGWSAPSVRVVSAPLVLPWNPGRKLP :: ...: : : . : . :: : : : . :: .::. .:: . : NP_612 -AAQDKGQVGPGAGPLELEGVKVPLEPGPKATEGGGEALPSGSECEVPLMGFPGPGLQSP 610 620 630 640 650 660 700 710 pF1KB3 RSSEGETLLPPLSQNS NP_612 LHAKPYI 670 713 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:50:26 2016 done: Thu Nov 3 20:50:28 2016 Total Scan time: 10.310 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]