FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3247, 361 aa
1>>>pF1KB3247 361 - 361 aa - 361 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7331+/-0.000338; mu= 15.6060+/- 0.021
mean_var=92.2095+/-18.440, 0's: 0 Z-trim(115.7): 45 B-trim: 0 in 0/60
Lambda= 0.133563
statistics sampled from 26339 (26384) to 26339 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.677), E-opt: 0.2 (0.309), width: 16
Scan time: 8.300
The best scores are: opt bits E(85289)
NP_001001391 (OMIM: 107269,609027) CD44 antigen is ( 361) 2443 480.7 2.1e-135
NP_001189486 (OMIM: 107269,609027) CD44 antigen is ( 294) 2002 395.7 6.9e-110
NP_001189485 (OMIM: 107269,609027) CD44 antigen is ( 340) 1551 308.8 1.1e-83
NP_001189484 (OMIM: 107269,609027) CD44 antigen is ( 429) 1541 307.0 5.1e-83
XP_011518788 (OMIM: 107269,609027) PREDICTED: CD44 ( 537) 1542 307.3 5.3e-83
XP_011518790 (OMIM: 107269,609027) PREDICTED: CD44 ( 425) 1534 305.6 1.3e-82
NP_001001390 (OMIM: 107269,609027) CD44 antigen is ( 493) 1534 305.7 1.4e-82
XP_011518791 (OMIM: 107269,609027) PREDICTED: CD44 ( 402) 1531 305.1 1.8e-82
XP_016874074 (OMIM: 107269,609027) PREDICTED: CD44 ( 403) 1531 305.1 1.8e-82
XP_005253297 (OMIM: 107269,609027) PREDICTED: CD44 ( 535) 1531 305.1 2.3e-82
NP_001001389 (OMIM: 107269,609027) CD44 antigen is ( 699) 1531 305.2 2.8e-82
XP_005253292 (OMIM: 107269,609027) PREDICTED: CD44 ( 700) 1531 305.2 2.8e-82
XP_006718453 (OMIM: 107269,609027) PREDICTED: CD44 ( 397) 1527 304.3 3.1e-82
XP_011518789 (OMIM: 107269,609027) PREDICTED: CD44 ( 446) 1527 304.3 3.4e-82
XP_016874073 (OMIM: 107269,609027) PREDICTED: CD44 ( 446) 1527 304.3 3.4e-82
XP_011518787 (OMIM: 107269,609027) PREDICTED: CD44 ( 656) 1529 304.8 3.5e-82
XP_011518786 (OMIM: 107269,609027) PREDICTED: CD44 ( 657) 1529 304.8 3.5e-82
XP_011518785 (OMIM: 107269,609027) PREDICTED: CD44 ( 658) 1529 304.8 3.5e-82
XP_005253296 (OMIM: 107269,609027) PREDICTED: CD44 ( 578) 1527 304.4 4.1e-82
XP_005253295 (OMIM: 107269,609027) PREDICTED: CD44 ( 580) 1527 304.4 4.1e-82
XP_011518784 (OMIM: 107269,609027) PREDICTED: CD44 ( 675) 1527 304.5 4.7e-82
XP_016874072 (OMIM: 107269,609027) PREDICTED: CD44 ( 699) 1527 304.5 4.8e-82
XP_005253291 (OMIM: 107269,609027) PREDICTED: CD44 ( 702) 1527 304.5 4.8e-82
XP_005253290 (OMIM: 107269,609027) PREDICTED: CD44 ( 703) 1527 304.5 4.8e-82
XP_006718451 (OMIM: 107269,609027) PREDICTED: CD44 ( 741) 1527 304.5 5e-82
XP_005253289 (OMIM: 107269,609027) PREDICTED: CD44 ( 742) 1527 304.5 5e-82
NP_000601 (OMIM: 107269,609027) CD44 antigen isofo ( 742) 1527 304.5 5e-82
XP_005253288 (OMIM: 107269,609027) PREDICTED: CD44 ( 743) 1527 304.5 5e-82
NP_001001392 (OMIM: 107269,609027) CD44 antigen is ( 139) 536 113.0 4.2e-25
NP_006682 (OMIM: 605702) lymphatic vessel endothel ( 322) 271 62.2 1.9e-09
>>NP_001001391 (OMIM: 107269,609027) CD44 antigen isofor (361 aa)
initn: 2443 init1: 2443 opt: 2443 Z-score: 2551.8 bits: 480.7 E(85289): 2.1e-135
Smith-Waterman score: 2443; 100.0% identity (100.0% similar) in 361 aa overlap (1-361:1-361)
10 20 30 40 50 60
pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 LVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIG
310 320 330 340 350 360
pF1KB3 V
:
NP_001 V
>>NP_001189486 (OMIM: 107269,609027) CD44 antigen isofor (294 aa)
initn: 2002 init1: 2002 opt: 2002 Z-score: 2093.8 bits: 395.7 E(85289): 6.9e-110
Smith-Waterman score: 2002; 100.0% identity (100.0% similar) in 293 aa overlap (1-293:1-293)
10 20 30 40 50 60
pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRS
250 260 270 280 290
310 320 330 340 350 360
pF1KB3 LVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIG
>>NP_001189485 (OMIM: 107269,609027) CD44 antigen isofor (340 aa)
initn: 1541 init1: 1541 opt: 1551 Z-score: 1623.3 bits: 308.8 E(85289): 1.1e-83
Smith-Waterman score: 2239; 94.2% identity (94.2% similar) in 361 aa overlap (1-361:1-340)
10 20 30 40 50 60
pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS
:::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATR-----------------
190 200 210 220
250 260 270 280 290 300
pF1KB3 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----HSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK
230 240 250 260 270
310 320 330 340 350 360
pF1KB3 LVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIG
280 290 300 310 320 330
pF1KB3 V
:
NP_001 V
340
>>NP_001189484 (OMIM: 107269,609027) CD44 antigen isofor (429 aa)
initn: 1574 init1: 1535 opt: 1541 Z-score: 1611.5 bits: 307.0 E(85289): 5.1e-83
Smith-Waterman score: 2058; 82.4% identity (82.4% similar) in 393 aa overlap (1-325:1-393)
10 20 30 40 50 60
pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
130 140 150 160 170 180
190 200 210 220
pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATR-----------------
::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATNRNDVTGGRRDPNHSEGS
190 200 210 220 230 240
230
pF1KB3 ---------------------------------------------------DQDTFHPSG
:::::::::
NP_001 TTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSG
250 260 270 280 290 300
240 250 260 270 280 290
pF1KB3 GSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSR
310 320 330 340 350 360
300 310 320 330 340 350
pF1KB3 RRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNL
:::::::::::::::::::::::::::::::::
NP_001 RRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNL
370 380 390 400 410 420
360
pF1KB3 QNVDMKIGV
NP_001 QNVDMKIGV
>--
initn: 231 init1: 231 opt: 231 Z-score: 247.3 bits: 54.6 E(85289): 4.9e-07
Smith-Waterman score: 231; 100.0% identity (100.0% similar) in 36 aa overlap (326-361:394-429)
300 310 320 330 340 350
pF1KB3 GQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNV
::::::::::::::::::::::::::::::
NP_001 GQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNV
370 380 390 400 410 420
360
pF1KB3 DMKIGV
::::::
NP_001 DMKIGV
>>XP_011518788 (OMIM: 107269,609027) PREDICTED: CD44 ant (537 aa)
initn: 2422 init1: 1527 opt: 1542 Z-score: 1611.2 bits: 307.3 E(85289): 5.3e-83
Smith-Waterman score: 1542; 93.8% identity (94.7% similar) in 243 aa overlap (1-242:1-243)
10 20 30 40 50 60
pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
130 140 150 160 170 180
190 200 210 220 230
pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATR-DQDTFHPSGGSHTTHG
:::::::::::::::::::::::::::::::::::::::::: . : :: : :
XP_011 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTASAHTSHPMQGRTTPSP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 SESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKK
.:
XP_011 EDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTT
250 260 270 280 290 300
>--
initn: 937 init1: 909 opt: 918 Z-score: 961.4 bits: 187.0 E(85289): 8.3e-47
Smith-Waterman score: 918; 60.4% identity (72.3% similar) in 278 aa overlap (89-361:278-537)
60 70 80 90 100 110
pF1KB3 TLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYC
: .::. . . . :. .:.: ..
XP_011 FFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQS
250 260 270 280 290 300
120 130 140 150 160 170
pF1KB3 FNASAPP-EEDCTSVTDLPNAFDGPITITIVNRD----GTRYVQKGEYRTNPEDIYPSNP
:..: ::: : :.. :.: ::. : : ...: :. . : :.
XP_011 FSTSHEGLEED----KDHPTTS----TLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHY
310 320 330 340 350
180 190 200 210 220 230
pF1KB3 TDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGG
: :. .:.. :. . : .: ...: . ::::::::::
XP_011 PHTKESRTFIPVTSAKTGSFGV----TAVTVGDSNS-----NVNR-SLSGDQDTFHPSGG
360 370 380 390 400
240 250 260 270 280 290
pF1KB3 SHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRR
410 420 430 440 450 460
300 310 320 330 340 350
pF1KB3 RCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQ
470 480 490 500 510 520
360
pF1KB3 NVDMKIGV
::::::::
XP_011 NVDMKIGV
530
>>XP_011518790 (OMIM: 107269,609027) PREDICTED: CD44 ant (425 aa)
initn: 1527 init1: 1527 opt: 1534 Z-score: 1604.3 bits: 305.6 E(85289): 1.3e-82
Smith-Waterman score: 2099; 83.7% identity (83.7% similar) in 393 aa overlap (1-329:1-393)
10 20 30 40 50 60
pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
130 140 150 160 170 180
190 200 210 220
pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT------------------
::::::::::::::::::::::::::::::::::::::::::
XP_011 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATNMDSSHSITLQPTANPNT
190 200 210 220 230 240
230
pF1KB3 ----------------------------------------------RDQDTFHPSGGSHT
::::::::::::::
XP_011 GLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSRDQDTFHPSGGSHT
250 260 270 280 290 300
240 250 260 270 280 290
pF1KB3 THGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCG
310 320 330 340 350 360
300 310 320 330 340 350
pF1KB3 QKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVD
:::::::::::::::::::::::::::::::::
XP_011 QKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVD
370 380 390 400 410 420
360
pF1KB3 MKIGV
XP_011 MKIGV
>>NP_001001390 (OMIM: 107269,609027) CD44 antigen isofor (493 aa)
initn: 2422 init1: 1527 opt: 1534 Z-score: 1603.4 bits: 305.7 E(85289): 1.4e-82
Smith-Waterman score: 1534; 97.8% identity (99.1% similar) in 229 aa overlap (1-229:1-228)
10 20 30 40 50 60
pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS
:::::::::::::::::::::::::::::::::::::::::: ..:. :
NP_001 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT-NMDSSHSITLQPTANPN
190 200 210 220 230
250 260 270 280 290 300
pF1KB3 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK
NP_001 TGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPN
240 250 260 270 280 290
>--
initn: 937 init1: 909 opt: 918 Z-score: 961.9 bits: 187.0 E(85289): 7.7e-47
Smith-Waterman score: 918; 60.4% identity (72.3% similar) in 278 aa overlap (89-361:234-493)
60 70 80 90 100 110
pF1KB3 TLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYC
: .::. . . . :. .:.: ..
NP_001 IPDEDSPWITDSTDRIPATNMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQS
210 220 230 240 250 260
120 130 140 150 160 170
pF1KB3 FNASAPP-EEDCTSVTDLPNAFDGPITITIVNRD----GTRYVQKGEYRTNPEDIYPSNP
:..: ::: : :.. :.: ::. : : ...: :. . : :.
NP_001 FSTSHEGLEED----KDHPTTS----TLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHY
270 280 290 300 310
180 190 200 210 220 230
pF1KB3 TDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGG
: :. .:.. :. . : .: ...: . ::::::::::
NP_001 PHTKESRTFIPVTSAKTGSFGV----TAVTVGDSNS-----NVNR-SLSGDQDTFHPSGG
320 330 340 350 360
240 250 260 270 280 290
pF1KB3 SHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRR
370 380 390 400 410 420
300 310 320 330 340 350
pF1KB3 RCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQ
430 440 450 460 470 480
360
pF1KB3 NVDMKIGV
::::::::
NP_001 NVDMKIGV
490
>>XP_011518791 (OMIM: 107269,609027) PREDICTED: CD44 ant (402 aa)
initn: 1559 init1: 1527 opt: 1531 Z-score: 1601.5 bits: 305.1 E(85289): 1.8e-82
Smith-Waterman score: 1531; 90.5% identity (94.4% similar) in 252 aa overlap (1-252:1-251)
10 20 30 40 50 60
pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS
:::::::::::::::::::::::::::::::::::::::::: ... :.: . .. .
XP_011 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNT-ISAGWEPNEEN
190 200 210 220 230
250 260 270 280 290 300
pF1KB3 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK
:.. : : :
XP_011 EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTT
240 250 260 270 280 290
>>XP_016874074 (OMIM: 107269,609027) PREDICTED: CD44 ant (403 aa)
initn: 1567 init1: 1527 opt: 1531 Z-score: 1601.4 bits: 305.1 E(85289): 1.8e-82
Smith-Waterman score: 2286; 89.3% identity (89.3% similar) in 393 aa overlap (1-351:1-393)
10 20 30 40 50 60
pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
130 140 150 160 170 180
190 200 210 220
pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT------------------
::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE
190 200 210 220 230 240
230 240 250
pF1KB3 ------------------------RDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS
::::::::::::::::::::::::::::::::::::
XP_016 DERDRHLSFSGSGIDDDEDFISSTRDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS
250 260 270 280 290 300
260 270 280 290 300 310
pF1KB3 GPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGL
310 320 330 340 350 360
320 330 340 350 360
pF1KB3 NGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIGV
:::::::::::::::::::::::::::::::::
XP_016 NGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIGV
370 380 390 400
>>XP_005253297 (OMIM: 107269,609027) PREDICTED: CD44 ant (535 aa)
initn: 2422 init1: 1527 opt: 1531 Z-score: 1599.8 bits: 305.1 E(85289): 2.3e-82
Smith-Waterman score: 1531; 90.5% identity (94.4% similar) in 252 aa overlap (1-252:1-251)
10 20 30 40 50 60
pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS
:::::::::::::::::::::::::::::::::::::::::: ... :.: . .. .
XP_005 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNT-ISAGWEPNEEN
190 200 210 220 230
250 260 270 280 290 300
pF1KB3 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK
:.. : : :
XP_005 EDERDRHLSFSGSGIDDDEDFISSTNMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQ
240 250 260 270 280 290
>--
initn: 947 init1: 909 opt: 918 Z-score: 961.4 bits: 187.0 E(85289): 8.2e-47
Smith-Waterman score: 926; 57.3% identity (72.2% similar) in 281 aa overlap (105-361:260-535)
80 90 100 110 120 130
pF1KB3 ETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTD
.: ..: .. . .. .: : . : :
XP_005 SAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTNMDSSHSITLQPTANP--NTGLVED
230 240 250 260 270 280
140 150 160 170 180
pF1KB3 LPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPT-----DDDVSSGSSSERSST
: . ::...: . .. . . : . .: .:.. : .::..: . :
XP_005 LDRT--GPLSMTTQQSNSQSFSTSHEGLEEDKD-HPTTSTLTSSNRNDVTGGRRDPNHSE
290 300 310 320 330 340
190 200 210 220 230
pF1KB3 SGGYIFYTFSTVHPIPDEDSPWIT-----------------DSTDRI--PATRDQDTFHP
.. .. ... .: :. .: ::.. . . :::::::
XP_005 GSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHP
350 360 370 380 390 400
240 250 260 270 280 290
pF1KB3 SGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVN
410 420 430 440 450 460
300 310 320 330 340 350
pF1KB3 SRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETR
470 480 490 500 510 520
360
pF1KB3 NLQNVDMKIGV
:::::::::::
XP_005 NLQNVDMKIGV
530
361 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 20:52:45 2016 done: Thu Nov 3 20:52:46 2016
Total Scan time: 8.300 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]