FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3247, 361 aa 1>>>pF1KB3247 361 - 361 aa - 361 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7331+/-0.000338; mu= 15.6060+/- 0.021 mean_var=92.2095+/-18.440, 0's: 0 Z-trim(115.7): 45 B-trim: 0 in 0/60 Lambda= 0.133563 statistics sampled from 26339 (26384) to 26339 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.677), E-opt: 0.2 (0.309), width: 16 Scan time: 8.300 The best scores are: opt bits E(85289) NP_001001391 (OMIM: 107269,609027) CD44 antigen is ( 361) 2443 480.7 2.1e-135 NP_001189486 (OMIM: 107269,609027) CD44 antigen is ( 294) 2002 395.7 6.9e-110 NP_001189485 (OMIM: 107269,609027) CD44 antigen is ( 340) 1551 308.8 1.1e-83 NP_001189484 (OMIM: 107269,609027) CD44 antigen is ( 429) 1541 307.0 5.1e-83 XP_011518788 (OMIM: 107269,609027) PREDICTED: CD44 ( 537) 1542 307.3 5.3e-83 XP_011518790 (OMIM: 107269,609027) PREDICTED: CD44 ( 425) 1534 305.6 1.3e-82 NP_001001390 (OMIM: 107269,609027) CD44 antigen is ( 493) 1534 305.7 1.4e-82 XP_011518791 (OMIM: 107269,609027) PREDICTED: CD44 ( 402) 1531 305.1 1.8e-82 XP_016874074 (OMIM: 107269,609027) PREDICTED: CD44 ( 403) 1531 305.1 1.8e-82 XP_005253297 (OMIM: 107269,609027) PREDICTED: CD44 ( 535) 1531 305.1 2.3e-82 NP_001001389 (OMIM: 107269,609027) CD44 antigen is ( 699) 1531 305.2 2.8e-82 XP_005253292 (OMIM: 107269,609027) PREDICTED: CD44 ( 700) 1531 305.2 2.8e-82 XP_006718453 (OMIM: 107269,609027) PREDICTED: CD44 ( 397) 1527 304.3 3.1e-82 XP_011518789 (OMIM: 107269,609027) PREDICTED: CD44 ( 446) 1527 304.3 3.4e-82 XP_016874073 (OMIM: 107269,609027) PREDICTED: CD44 ( 446) 1527 304.3 3.4e-82 XP_011518787 (OMIM: 107269,609027) PREDICTED: CD44 ( 656) 1529 304.8 3.5e-82 XP_011518786 (OMIM: 107269,609027) PREDICTED: CD44 ( 657) 1529 304.8 3.5e-82 XP_011518785 (OMIM: 107269,609027) PREDICTED: CD44 ( 658) 1529 304.8 3.5e-82 XP_005253296 (OMIM: 107269,609027) PREDICTED: CD44 ( 578) 1527 304.4 4.1e-82 XP_005253295 (OMIM: 107269,609027) PREDICTED: CD44 ( 580) 1527 304.4 4.1e-82 XP_011518784 (OMIM: 107269,609027) PREDICTED: CD44 ( 675) 1527 304.5 4.7e-82 XP_016874072 (OMIM: 107269,609027) PREDICTED: CD44 ( 699) 1527 304.5 4.8e-82 XP_005253291 (OMIM: 107269,609027) PREDICTED: CD44 ( 702) 1527 304.5 4.8e-82 XP_005253290 (OMIM: 107269,609027) PREDICTED: CD44 ( 703) 1527 304.5 4.8e-82 XP_006718451 (OMIM: 107269,609027) PREDICTED: CD44 ( 741) 1527 304.5 5e-82 XP_005253289 (OMIM: 107269,609027) PREDICTED: CD44 ( 742) 1527 304.5 5e-82 NP_000601 (OMIM: 107269,609027) CD44 antigen isofo ( 742) 1527 304.5 5e-82 XP_005253288 (OMIM: 107269,609027) PREDICTED: CD44 ( 743) 1527 304.5 5e-82 NP_001001392 (OMIM: 107269,609027) CD44 antigen is ( 139) 536 113.0 4.2e-25 NP_006682 (OMIM: 605702) lymphatic vessel endothel ( 322) 271 62.2 1.9e-09 >>NP_001001391 (OMIM: 107269,609027) CD44 antigen isofor (361 aa) initn: 2443 init1: 2443 opt: 2443 Z-score: 2551.8 bits: 480.7 E(85289): 2.1e-135 Smith-Waterman score: 2443; 100.0% identity (100.0% similar) in 361 aa overlap (1-361:1-361) 10 20 30 40 50 60 pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 LVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIG 310 320 330 340 350 360 pF1KB3 V : NP_001 V >>NP_001189486 (OMIM: 107269,609027) CD44 antigen isofor (294 aa) initn: 2002 init1: 2002 opt: 2002 Z-score: 2093.8 bits: 395.7 E(85289): 6.9e-110 Smith-Waterman score: 2002; 100.0% identity (100.0% similar) in 293 aa overlap (1-293:1-293) 10 20 30 40 50 60 pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRS 250 260 270 280 290 310 320 330 340 350 360 pF1KB3 LVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIG >>NP_001189485 (OMIM: 107269,609027) CD44 antigen isofor (340 aa) initn: 1541 init1: 1541 opt: 1551 Z-score: 1623.3 bits: 308.8 E(85289): 1.1e-83 Smith-Waterman score: 2239; 94.2% identity (94.2% similar) in 361 aa overlap (1-361:1-340) 10 20 30 40 50 60 pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS ::::::::::::::::::::::::::::::::::::::::::: NP_001 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATR----------------- 190 200 210 220 250 260 270 280 290 300 pF1KB3 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ----HSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK 230 240 250 260 270 310 320 330 340 350 360 pF1KB3 LVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIG 280 290 300 310 320 330 pF1KB3 V : NP_001 V 340 >>NP_001189484 (OMIM: 107269,609027) CD44 antigen isofor (429 aa) initn: 1574 init1: 1535 opt: 1541 Z-score: 1611.5 bits: 307.0 E(85289): 5.1e-83 Smith-Waterman score: 2058; 82.4% identity (82.4% similar) in 393 aa overlap (1-325:1-393) 10 20 30 40 50 60 pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 130 140 150 160 170 180 190 200 210 220 pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATR----------------- :::::::::::::::::::::::::::::::::::::::::: NP_001 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATNRNDVTGGRRDPNHSEGS 190 200 210 220 230 240 230 pF1KB3 ---------------------------------------------------DQDTFHPSG ::::::::: NP_001 TTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSG 250 260 270 280 290 300 240 250 260 270 280 290 pF1KB3 GSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSR 310 320 330 340 350 360 300 310 320 330 340 350 pF1KB3 RRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNL ::::::::::::::::::::::::::::::::: NP_001 RRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNL 370 380 390 400 410 420 360 pF1KB3 QNVDMKIGV NP_001 QNVDMKIGV >-- initn: 231 init1: 231 opt: 231 Z-score: 247.3 bits: 54.6 E(85289): 4.9e-07 Smith-Waterman score: 231; 100.0% identity (100.0% similar) in 36 aa overlap (326-361:394-429) 300 310 320 330 340 350 pF1KB3 GQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNV :::::::::::::::::::::::::::::: NP_001 GQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNV 370 380 390 400 410 420 360 pF1KB3 DMKIGV :::::: NP_001 DMKIGV >>XP_011518788 (OMIM: 107269,609027) PREDICTED: CD44 ant (537 aa) initn: 2422 init1: 1527 opt: 1542 Z-score: 1611.2 bits: 307.3 E(85289): 5.3e-83 Smith-Waterman score: 1542; 93.8% identity (94.7% similar) in 243 aa overlap (1-242:1-243) 10 20 30 40 50 60 pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATR-DQDTFHPSGGSHTTHG :::::::::::::::::::::::::::::::::::::::::: . : :: : : XP_011 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTASAHTSHPMQGRTTPSP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 SESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKK .: XP_011 EDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTT 250 260 270 280 290 300 >-- initn: 937 init1: 909 opt: 918 Z-score: 961.4 bits: 187.0 E(85289): 8.3e-47 Smith-Waterman score: 918; 60.4% identity (72.3% similar) in 278 aa overlap (89-361:278-537) 60 70 80 90 100 110 pF1KB3 TLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYC : .::. . . . :. .:.: .. XP_011 FFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQS 250 260 270 280 290 300 120 130 140 150 160 170 pF1KB3 FNASAPP-EEDCTSVTDLPNAFDGPITITIVNRD----GTRYVQKGEYRTNPEDIYPSNP :..: ::: : :.. :.: ::. : : ...: :. . : :. XP_011 FSTSHEGLEED----KDHPTTS----TLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHY 310 320 330 340 350 180 190 200 210 220 230 pF1KB3 TDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGG : :. .:.. :. . : .: ...: . :::::::::: XP_011 PHTKESRTFIPVTSAKTGSFGV----TAVTVGDSNS-----NVNR-SLSGDQDTFHPSGG 360 370 380 390 400 240 250 260 270 280 290 pF1KB3 SHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRR 410 420 430 440 450 460 300 310 320 330 340 350 pF1KB3 RCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQ 470 480 490 500 510 520 360 pF1KB3 NVDMKIGV :::::::: XP_011 NVDMKIGV 530 >>XP_011518790 (OMIM: 107269,609027) PREDICTED: CD44 ant (425 aa) initn: 1527 init1: 1527 opt: 1534 Z-score: 1604.3 bits: 305.6 E(85289): 1.3e-82 Smith-Waterman score: 2099; 83.7% identity (83.7% similar) in 393 aa overlap (1-329:1-393) 10 20 30 40 50 60 pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 130 140 150 160 170 180 190 200 210 220 pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT------------------ :::::::::::::::::::::::::::::::::::::::::: XP_011 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATNMDSSHSITLQPTANPNT 190 200 210 220 230 240 230 pF1KB3 ----------------------------------------------RDQDTFHPSGGSHT :::::::::::::: XP_011 GLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSRDQDTFHPSGGSHT 250 260 270 280 290 300 240 250 260 270 280 290 pF1KB3 THGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCG 310 320 330 340 350 360 300 310 320 330 340 350 pF1KB3 QKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVD ::::::::::::::::::::::::::::::::: XP_011 QKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVD 370 380 390 400 410 420 360 pF1KB3 MKIGV XP_011 MKIGV >>NP_001001390 (OMIM: 107269,609027) CD44 antigen isofor (493 aa) initn: 2422 init1: 1527 opt: 1534 Z-score: 1603.4 bits: 305.7 E(85289): 1.4e-82 Smith-Waterman score: 1534; 97.8% identity (99.1% similar) in 229 aa overlap (1-229:1-228) 10 20 30 40 50 60 pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS :::::::::::::::::::::::::::::::::::::::::: ..:. : NP_001 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT-NMDSSHSITLQPTANPN 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK NP_001 TGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPN 240 250 260 270 280 290 >-- initn: 937 init1: 909 opt: 918 Z-score: 961.9 bits: 187.0 E(85289): 7.7e-47 Smith-Waterman score: 918; 60.4% identity (72.3% similar) in 278 aa overlap (89-361:234-493) 60 70 80 90 100 110 pF1KB3 TLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYC : .::. . . . :. .:.: .. NP_001 IPDEDSPWITDSTDRIPATNMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQS 210 220 230 240 250 260 120 130 140 150 160 170 pF1KB3 FNASAPP-EEDCTSVTDLPNAFDGPITITIVNRD----GTRYVQKGEYRTNPEDIYPSNP :..: ::: : :.. :.: ::. : : ...: :. . : :. NP_001 FSTSHEGLEED----KDHPTTS----TLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHY 270 280 290 300 310 180 190 200 210 220 230 pF1KB3 TDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGG : :. .:.. :. . : .: ...: . :::::::::: NP_001 PHTKESRTFIPVTSAKTGSFGV----TAVTVGDSNS-----NVNR-SLSGDQDTFHPSGG 320 330 340 350 360 240 250 260 270 280 290 pF1KB3 SHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRR 370 380 390 400 410 420 300 310 320 330 340 350 pF1KB3 RCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQ 430 440 450 460 470 480 360 pF1KB3 NVDMKIGV :::::::: NP_001 NVDMKIGV 490 >>XP_011518791 (OMIM: 107269,609027) PREDICTED: CD44 ant (402 aa) initn: 1559 init1: 1527 opt: 1531 Z-score: 1601.5 bits: 305.1 E(85289): 1.8e-82 Smith-Waterman score: 1531; 90.5% identity (94.4% similar) in 252 aa overlap (1-252:1-251) 10 20 30 40 50 60 pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS :::::::::::::::::::::::::::::::::::::::::: ... :.: . .. . XP_011 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNT-ISAGWEPNEEN 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK :.. : : : XP_011 EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTT 240 250 260 270 280 290 >>XP_016874074 (OMIM: 107269,609027) PREDICTED: CD44 ant (403 aa) initn: 1567 init1: 1527 opt: 1531 Z-score: 1601.4 bits: 305.1 E(85289): 1.8e-82 Smith-Waterman score: 2286; 89.3% identity (89.3% similar) in 393 aa overlap (1-351:1-393) 10 20 30 40 50 60 pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 130 140 150 160 170 180 190 200 210 220 pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT------------------ :::::::::::::::::::::::::::::::::::::::::: XP_016 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE 190 200 210 220 230 240 230 240 250 pF1KB3 ------------------------RDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS :::::::::::::::::::::::::::::::::::: XP_016 DERDRHLSFSGSGIDDDEDFISSTRDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 250 260 270 280 290 300 260 270 280 290 300 310 pF1KB3 GPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGL 310 320 330 340 350 360 320 330 340 350 360 pF1KB3 NGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIGV ::::::::::::::::::::::::::::::::: XP_016 NGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIGV 370 380 390 400 >>XP_005253297 (OMIM: 107269,609027) PREDICTED: CD44 ant (535 aa) initn: 2422 init1: 1527 opt: 1531 Z-score: 1599.8 bits: 305.1 E(85289): 2.3e-82 Smith-Waterman score: 1531; 90.5% identity (94.4% similar) in 252 aa overlap (1-252:1-251) 10 20 30 40 50 60 pF1KB3 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGS :::::::::::::::::::::::::::::::::::::::::: ... :.: . .. . XP_005 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNT-ISAGWEPNEEN 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 ESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKK :.. : : : XP_005 EDERDRHLSFSGSGIDDDEDFISSTNMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQ 240 250 260 270 280 290 >-- initn: 947 init1: 909 opt: 918 Z-score: 961.4 bits: 187.0 E(85289): 8.2e-47 Smith-Waterman score: 926; 57.3% identity (72.2% similar) in 281 aa overlap (105-361:260-535) 80 90 100 110 120 130 pF1KB3 ETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTD .: ..: .. . .. .: : . : : XP_005 SAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTNMDSSHSITLQPTANP--NTGLVED 230 240 250 260 270 280 140 150 160 170 180 pF1KB3 LPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPT-----DDDVSSGSSSERSST : . ::...: . .. . . : . .: .:.. : .::..: . : XP_005 LDRT--GPLSMTTQQSNSQSFSTSHEGLEEDKD-HPTTSTLTSSNRNDVTGGRRDPNHSE 290 300 310 320 330 340 190 200 210 220 230 pF1KB3 SGGYIFYTFSTVHPIPDEDSPWIT-----------------DSTDRI--PATRDQDTFHP .. .. ... .: :. .: ::.. . . ::::::: XP_005 GSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHP 350 360 370 380 390 400 240 250 260 270 280 290 pF1KB3 SGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVN 410 420 430 440 450 460 300 310 320 330 340 350 pF1KB3 SRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETR 470 480 490 500 510 520 360 pF1KB3 NLQNVDMKIGV ::::::::::: XP_005 NLQNVDMKIGV 530 361 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:52:45 2016 done: Thu Nov 3 20:52:46 2016 Total Scan time: 8.300 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]