FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3277, 605 aa 1>>>pF1KB3277 605 - 605 aa - 605 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.9818+/-0.000435; mu= 1.8320+/- 0.027 mean_var=203.4415+/-42.264, 0's: 0 Z-trim(118.0): 107 B-trim: 1298 in 1/55 Lambda= 0.089920 statistics sampled from 30404 (30513) to 30404 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.358), width: 16 Scan time: 10.600 The best scores are: opt bits E(85289) NP_000715 (OMIM: 600003,611876) voltage-dependent ( 605) 4013 533.7 6.9e-151 NP_963865 (OMIM: 600003,611876) voltage-dependent ( 632) 3897 518.7 2.4e-146 NP_963890 (OMIM: 600003,611876) voltage-dependent ( 660) 3897 518.7 2.5e-146 XP_006717565 (OMIM: 600003,611876) PREDICTED: volt ( 600) 3894 518.2 3e-146 NP_963884 (OMIM: 600003,611876) voltage-dependent ( 606) 3894 518.3 3.1e-146 NP_963864 (OMIM: 600003,611876) voltage-dependent ( 612) 3894 518.3 3.1e-146 NP_001316989 (OMIM: 600003,611876) voltage-depende ( 567) 2619 352.8 1.8e-96 XP_005252645 (OMIM: 600003,611876) PREDICTED: volt ( 574) 2619 352.8 1.8e-96 NP_001161417 (OMIM: 600003,611876) voltage-depende ( 594) 2619 352.8 1.9e-96 NP_963887 (OMIM: 600003,611876) voltage-dependent ( 622) 2619 352.9 1.9e-96 XP_011517961 (OMIM: 600003,611876) PREDICTED: volt ( 582) 2617 352.6 2.2e-96 NP_963866 (OMIM: 600003,611876) voltage-dependent ( 608) 2617 352.6 2.3e-96 NP_963891 (OMIM: 600003,611876) voltage-dependent ( 636) 2617 352.6 2.4e-96 XP_016872114 (OMIM: 600003,611876) PREDICTED: volt ( 380) 2506 338.1 3.4e-92 XP_005252648 (OMIM: 600003,611876) PREDICTED: volt ( 380) 2506 338.1 3.4e-92 XP_005257702 (OMIM: 114207) PREDICTED: voltage-dep ( 643) 2337 316.3 2e-85 XP_006722135 (OMIM: 114207) PREDICTED: voltage-dep ( 596) 2336 316.1 2.1e-85 XP_016880513 (OMIM: 114207) PREDICTED: voltage-dep ( 599) 2334 315.9 2.5e-85 NP_954855 (OMIM: 114207) voltage-dependent L-type ( 523) 2201 298.6 3.5e-80 XP_005257703 (OMIM: 114207) PREDICTED: voltage-dep ( 400) 1690 232.2 2.6e-60 XP_016880515 (OMIM: 114207) PREDICTED: voltage-dep ( 431) 1576 217.5 7.7e-56 XP_016880514 (OMIM: 114207) PREDICTED: voltage-dep ( 551) 1473 204.2 9.9e-52 NP_000714 (OMIM: 114207) voltage-dependent L-type ( 598) 1473 204.2 1.1e-51 XP_016880516 (OMIM: 114207) PREDICTED: voltage-dep ( 370) 1379 191.9 3.4e-48 XP_016880518 (OMIM: 114207) PREDICTED: voltage-dep ( 370) 1379 191.9 3.4e-48 XP_016880517 (OMIM: 114207) PREDICTED: voltage-dep ( 370) 1379 191.9 3.4e-48 NP_954856 (OMIM: 114207) voltage-dependent L-type ( 478) 1337 186.5 1.8e-46 NP_001317046 (OMIM: 601949,607682,613855) voltage- ( 334) 1320 184.2 6.2e-46 XP_011510098 (OMIM: 601949,607682,613855) PREDICTE ( 472) 1320 184.3 8.3e-46 NP_001317047 (OMIM: 601949,607682,613855) voltage- ( 473) 1320 184.3 8.3e-46 NP_001307651 (OMIM: 601949,607682,613855) voltage- ( 473) 1320 184.3 8.3e-46 NP_001005747 (OMIM: 601949,607682,613855) voltage- ( 486) 1320 184.3 8.5e-46 NP_001005746 (OMIM: 601949,607682,613855) voltage- ( 502) 1320 184.3 8.7e-46 NP_000717 (OMIM: 601949,607682,613855) voltage-dep ( 520) 1320 184.3 8.9e-46 XP_016860374 (OMIM: 601949,607682,613855) PREDICTE ( 302) 1233 172.9 1.4e-42 NP_001317043 (OMIM: 601949,607682,613855) voltage- ( 302) 1233 172.9 1.4e-42 NP_001193844 (OMIM: 601958) voltage-dependent L-ty ( 443) 1194 167.9 6.5e-41 NP_001193846 (OMIM: 601958) voltage-dependent L-ty ( 471) 1194 167.9 6.9e-41 NP_001193845 (OMIM: 601958) voltage-dependent L-ty ( 483) 1194 167.9 7e-41 NP_000716 (OMIM: 601958) voltage-dependent L-type ( 484) 1194 167.9 7e-41 XP_016875447 (OMIM: 601958) PREDICTED: voltage-dep ( 308) 1100 155.6 2.3e-37 XP_016875446 (OMIM: 601958) PREDICTED: voltage-dep ( 308) 1100 155.6 2.3e-37 XP_011537030 (OMIM: 601958) PREDICTED: voltage-dep ( 308) 1100 155.6 2.3e-37 XP_016875448 (OMIM: 601958) PREDICTED: voltage-dep ( 308) 1100 155.6 2.3e-37 XP_011537029 (OMIM: 601958) PREDICTED: voltage-dep ( 308) 1100 155.6 2.3e-37 NP_001139270 (OMIM: 601949,607682,613855) voltage- ( 458) 1008 143.8 1.2e-33 XP_016880519 (OMIM: 114207) PREDICTED: voltage-dep ( 355) 826 120.1 1.3e-26 XP_016860375 (OMIM: 601949,607682,613855) PREDICTE ( 281) 807 117.6 5.9e-26 NP_001317045 (OMIM: 601949,607682,613855) voltage- ( 410) 801 116.9 1.4e-25 NP_001317044 (OMIM: 601949,607682,613855) voltage- ( 423) 801 116.9 1.4e-25 >>NP_000715 (OMIM: 600003,611876) voltage-dependent L-ty (605 aa) initn: 4013 init1: 4013 opt: 4013 Z-score: 2829.9 bits: 533.7 E(85289): 6.9e-151 Smith-Waterman score: 4013; 100.0% identity (100.0% similar) in 605 aa overlap (1-605:1-605) 10 20 30 40 50 60 pF1KB3 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 ENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 APHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 APHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 GSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD 550 560 570 580 590 600 pF1KB3 VYIRQ ::::: NP_000 VYIRQ >>NP_963865 (OMIM: 600003,611876) voltage-dependent L-ty (632 aa) initn: 3897 init1: 3897 opt: 3897 Z-score: 2748.3 bits: 518.7 E(85289): 2.4e-146 Smith-Waterman score: 3897; 99.7% identity (99.7% similar) in 592 aa overlap (14-605:41-632) 10 20 30 40 pF1KB3 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRRE : ::::::::::::::::::::::::::: NP_963 KISYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRRE 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB3 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW 80 90 100 110 120 130 110 120 130 140 150 160 pF1KB3 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS 140 150 160 170 180 190 170 180 190 200 210 220 pF1KB3 TPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 TPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVV 200 210 220 230 240 250 230 240 250 260 270 280 pF1KB3 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK 260 270 280 290 300 310 290 300 310 320 330 340 pF1KB3 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI 320 330 340 350 360 370 350 360 370 380 390 400 pF1KB3 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE 380 390 400 410 420 430 410 420 430 440 450 460 pF1KB3 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE 440 450 460 470 480 490 470 480 490 500 510 520 pF1KB3 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH 500 510 520 530 540 550 530 540 550 560 570 580 pF1KB3 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD 560 570 580 590 600 610 590 600 pF1KB3 GEVISKKRNEAGEWNRDVYIRQ :::::::::::::::::::::: NP_963 GEVISKKRNEAGEWNRDVYIRQ 620 630 >>NP_963890 (OMIM: 600003,611876) voltage-dependent L-ty (660 aa) initn: 3897 init1: 3897 opt: 3897 Z-score: 2748.0 bits: 518.7 E(85289): 2.5e-146 Smith-Waterman score: 3897; 99.7% identity (99.7% similar) in 592 aa overlap (14-605:69-660) 10 20 30 40 pF1KB3 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRRE : ::::::::::::::::::::::::::: NP_963 AQSYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRRE 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB3 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB3 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB3 TPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 TPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVV 220 230 240 250 260 270 230 240 250 260 270 280 pF1KB3 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK 280 290 300 310 320 330 290 300 310 320 330 340 pF1KB3 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI 340 350 360 370 380 390 350 360 370 380 390 400 pF1KB3 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE 400 410 420 430 440 450 410 420 430 440 450 460 pF1KB3 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE 460 470 480 490 500 510 470 480 490 500 510 520 pF1KB3 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH 520 530 540 550 560 570 530 540 550 560 570 580 pF1KB3 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD 580 590 600 610 620 630 590 600 pF1KB3 GEVISKKRNEAGEWNRDVYIRQ :::::::::::::::::::::: NP_963 GEVISKKRNEAGEWNRDVYIRQ 640 650 660 >>XP_006717565 (OMIM: 600003,611876) PREDICTED: voltage- (600 aa) initn: 3894 init1: 3894 opt: 3894 Z-score: 2746.5 bits: 518.2 E(85289): 3e-146 Smith-Waterman score: 3894; 100.0% identity (100.0% similar) in 589 aa overlap (17-605:12-600) 10 20 30 40 50 60 pF1KB3 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV :::::::::::::::::::::::::::::::::::::::::::: XP_006 MYYDDDEPSEVGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAE 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 ENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB3 SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB3 AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB3 LSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSS 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB3 APHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 APHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETH 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB3 GSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD 540 550 560 570 580 590 pF1KB3 VYIRQ ::::: XP_006 VYIRQ 600 >>NP_963884 (OMIM: 600003,611876) voltage-dependent L-ty (606 aa) initn: 3894 init1: 3894 opt: 3894 Z-score: 2746.5 bits: 518.3 E(85289): 3.1e-146 Smith-Waterman score: 3894; 100.0% identity (100.0% similar) in 589 aa overlap (17-605:18-606) 10 20 30 40 50 pF1KB3 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKP ::::::::::::::::::::::::::::::::::::::::::: NP_963 MLDRRLIAPQTKYIIPGGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 VAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 VAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 SPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 SPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 EENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 EENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 EVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 EVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEV 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 QSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 QSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKS 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 QAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 QAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 LLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 LLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSS 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 SAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 SAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDET 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 HGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 HGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNR 550 560 570 580 590 600 600 pF1KB3 DVYIRQ :::::: NP_963 DVYIRQ >>NP_963864 (OMIM: 600003,611876) voltage-dependent L-ty (612 aa) initn: 3894 init1: 3894 opt: 3894 Z-score: 2746.4 bits: 518.3 E(85289): 3.1e-146 Smith-Waterman score: 3894; 100.0% identity (100.0% similar) in 589 aa overlap (17-605:24-612) 10 20 30 40 50 pF1KB3 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLE ::::::::::::::::::::::::::::::::::::: NP_963 MKATWIRLLKRAKGGRLKNSDICGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 KAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 KAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGC 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 EIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 EIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDID 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 ATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 ATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 PSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 PSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTR 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 SSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 SSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLI 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 KSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 KSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 SSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 SSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKS 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 QHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 QHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDH 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 NHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 NHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE 550 560 570 580 590 600 600 pF1KB3 AGEWNRDVYIRQ :::::::::::: NP_963 AGEWNRDVYIRQ 610 >>NP_001316989 (OMIM: 600003,611876) voltage-dependent L (567 aa) initn: 3709 init1: 2599 opt: 2619 Z-score: 1853.0 bits: 352.8 E(85289): 1.8e-96 Smith-Waterman score: 3642; 93.2% identity (93.7% similar) in 605 aa overlap (1-605:1-567) 10 20 30 40 50 60 pF1KB3 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAE ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSA----------- 130 140 150 160 190 200 210 220 230 240 pF1KB3 ENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYE :.:. :.::::::::::::::::::::::::::: NP_001 -----------------------KQKQ----KSTEHTPPYDVVPSMRPVVLVGPSLKGYE 170 180 190 200 250 260 270 280 290 300 pF1KB3 VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB3 SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB3 AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB3 LSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSS 390 400 410 420 430 440 490 500 510 520 530 540 pF1KB3 APHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETH 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB3 GSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD 510 520 530 540 550 560 pF1KB3 VYIRQ ::::: NP_001 VYIRQ >>XP_005252645 (OMIM: 600003,611876) PREDICTED: voltage- (574 aa) initn: 3590 init1: 2599 opt: 2619 Z-score: 1852.9 bits: 352.8 E(85289): 1.8e-96 Smith-Waterman score: 3523; 93.0% identity (93.5% similar) in 589 aa overlap (17-605:24-574) 10 20 30 40 50 pF1KB3 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLE ::::::::::::::::::::::::::::::::::::: XP_005 MKATWIRLLKRAKGGRLKNSDICGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 KAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGC 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 EIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDID :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSA---- 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 ATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVG :.:. :.:::::::::::::::::::: XP_005 ------------------------------KQKQ----KSTEHTPPYDVVPSMRPVVLVG 180 190 200 240 250 260 270 280 290 pF1KB3 PSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTR 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB3 SSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLI 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB3 KSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPS 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB3 SSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKS 390 400 410 420 430 440 480 490 500 510 520 530 pF1KB3 QHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDH 450 460 470 480 490 500 540 550 560 570 580 590 pF1KB3 NHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE 510 520 530 540 550 560 600 pF1KB3 AGEWNRDVYIRQ :::::::::::: XP_005 AGEWNRDVYIRQ 570 >>NP_001161417 (OMIM: 600003,611876) voltage-dependent L (594 aa) initn: 3593 init1: 2599 opt: 2619 Z-score: 1852.7 bits: 352.8 E(85289): 1.9e-96 Smith-Waterman score: 3526; 92.7% identity (93.2% similar) in 592 aa overlap (14-605:41-594) 10 20 30 40 pF1KB3 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRRE : ::::::::::::::::::::::::::: NP_001 KISYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRRE 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB3 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW 80 90 100 110 120 130 110 120 130 140 150 160 pF1KB3 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS 140 150 160 170 180 190 170 180 190 200 210 220 pF1KB3 TPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVV :::::: :.:. :.:::::::::: NP_001 TPPSSA----------------------------------KQKQ----KSTEHTPPYDVV 200 210 230 240 250 260 270 280 pF1KB3 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK 220 230 240 250 260 270 290 300 310 320 330 340 pF1KB3 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB3 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE 340 350 360 370 380 390 410 420 430 440 450 460 pF1KB3 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE 400 410 420 430 440 450 470 480 490 500 510 520 pF1KB3 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH 460 470 480 490 500 510 530 540 550 560 570 580 pF1KB3 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD 520 530 540 550 560 570 590 600 pF1KB3 GEVISKKRNEAGEWNRDVYIRQ :::::::::::::::::::::: NP_001 GEVISKKRNEAGEWNRDVYIRQ 580 590 >>NP_963887 (OMIM: 600003,611876) voltage-dependent L-ty (622 aa) initn: 3593 init1: 2599 opt: 2619 Z-score: 1852.4 bits: 352.9 E(85289): 1.9e-96 Smith-Waterman score: 3526; 92.7% identity (93.2% similar) in 592 aa overlap (14-605:69-622) 10 20 30 40 pF1KB3 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRRE : ::::::::::::::::::::::::::: NP_963 AQSYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRRE 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB3 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB3 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB3 TPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVV :::::: :.:. :.:::::::::: NP_963 TPPSSA----------------------------------KQKQ----KSTEHTPPYDVV 220 230 240 230 240 250 260 270 280 pF1KB3 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB3 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB3 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB3 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB3 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB3 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD 550 560 570 580 590 600 590 600 pF1KB3 GEVISKKRNEAGEWNRDVYIRQ :::::::::::::::::::::: NP_963 GEVISKKRNEAGEWNRDVYIRQ 610 620 605 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Nov 8 17:10:42 2016 done: Tue Nov 8 17:10:44 2016 Total Scan time: 10.600 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]