FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3283, 1189 aa 1>>>pF1KB3283 1189 - 1189 aa - 1189 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6161+/-0.000875; mu= 14.4728+/- 0.053 mean_var=194.8709+/-38.553, 0's: 0 Z-trim(114.6): 43 B-trim: 139 in 1/51 Lambda= 0.091876 statistics sampled from 15093 (15131) to 15093 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.778), E-opt: 0.2 (0.465), width: 16 Scan time: 6.180 The best scores are: opt bits E(32554) CCDS6022.1 HR gene_id:55806|Hs108|chr8 (1189) 8569 1149.1 0 CCDS6023.1 HR gene_id:55806|Hs108|chr8 (1134) 7754 1041.1 0 >>CCDS6022.1 HR gene_id:55806|Hs108|chr8 (1189 aa) initn: 8569 init1: 8569 opt: 8569 Z-score: 6145.4 bits: 1149.1 E(32554): 0 Smith-Waterman score: 8569; 99.9% identity (99.9% similar) in 1189 aa overlap (1-1189:1-1189) 10 20 30 40 50 60 pF1KB3 MESTPSFLKGTPTWEKTAPENGIVRQEPGSPPRDGLHHGPLCLGEPAPFWRGVLSTPDSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MESTPSFLKGTPTWEKTAPENGIVRQEPGSPPRDGLHHGPLCLGEPAPFWRGVLSTPDSW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LPPGFPQGPKDMLPLVEGEGPQNGERKVNWLGSKEGLRWKEAMLTHPLAFCGPACPPRCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LPPGFPQGPKDMLPLVEGEGPQNGERKVNWLGSKEGLRWKEAMLTHPLAFCGPACPPRCG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 PLMPEHSGGHLKSDPVAFRPWHCPFLLETKILERAPFWVPTCLPPYLVSGLPPEHPCDWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 PLMPEHSGGHLKSDPVAFRPWHCPFLLETKILERAPFWVPTCLPPYLVSGLPPEHPCDWP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LTPHPWVYSGGQPKVPSAFSLGSKGFYYKDPSIPRLAKEPLAAAEPGLFGLNSGGHLQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LTPHPWVYSGGQPKVPSAFSLGSKGFYYKDPSIPRLAKEPLAAAEPGLFGLNSGGHLQRA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 GEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGDLGPCGKCQEGLEGGASGASEPSE :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: CCDS60 NLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 GLQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GLQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 GPGSGPDSRLSTGLAKHLLSGLGDRLCRLLRREREALAWAQREGQGPAVTEDSPGIPRCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GPGSGPDSRLSTGLAKHLLSGLGDRLCRLLRREREALAWAQREGQGPAVTEDSPGIPRCC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SRCHHGLFNTHWRCPRCSHRLCVACGRVAGTGRAREKAGFQEQSAEECTQEAGHAACSLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SRCHHGLFNTHWRCPRCSHRLCVACGRVAGTGRAREKAGFQEQSAEECTQEAGHAACSLM 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 LTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWAPGDAGQQKESTQKTPPTPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWAPGDAGQQKESTQKTPPTPQP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 SCNGDTHRTKSIKEETPDSAETPAEDRAGRGPLPCPSLCELLASTAVKLCLGHERIHMAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SCNGDTHRTKSIKEETPDSAETPAEDRAGRGPLPCPSLCELLASTAVKLCLGHERIHMAF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 APVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGPGLRKGLGLPLSPVRPRLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 APVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGPGLRKGLGLPLSPVRPRLP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 PPGALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNLWGTEALGALGGQVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 PPGALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNLWGTEALGALGGQVQA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 LSPLGPPQPSSLGSTTFWEGFSWPELRPKSDEGSVLLLHRALGDEDTSRVENLAASLPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LSPLGPPQPSSLGSTTFWEGFSWPELRPKSDEGSVLLLHRALGDEDTSRVENLAASLPLP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 EYCALHGKLNLASYLPPGLALRPLEPQLWAAYGVSPHRGHLGTKNLCVEVADLVSILVHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EYCALHGKLNLASYLPPGLALRPLEPQLWAAYGVSPHRGHLGTKNLCVEVADLVSILVHA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB3 DTPLPAWHRAQKDFLSGLDGEGLWSPGSQVSTVWHVFRAQDAQRIRRFLQMVCPAGAGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 DTPLPAWHRAQKDFLSGLDGEGLWSPGSQVSTVWHVFRAQDAQRIRRFLQMVCPAGAGAL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB3 EPGAPGSCYLDAGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EPGAPGSCYLDAGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHF 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 pF1KB3 LSPETSALSAQLCHQGPSLPPDCHLLYAQMDWAVFQAVKVAVGTLQEAK ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LSPETSALSAQLCHQGPSLPPDCHLLYAQMDWAVFQAVKVAVGTLQEAK 1150 1160 1170 1180 >>CCDS6023.1 HR gene_id:55806|Hs108|chr8 (1134 aa) initn: 7754 init1: 7754 opt: 7754 Z-score: 5561.8 bits: 1041.1 E(32554): 0 Smith-Waterman score: 8049; 95.3% identity (95.3% similar) in 1189 aa overlap (1-1189:1-1134) 10 20 30 40 50 60 pF1KB3 MESTPSFLKGTPTWEKTAPENGIVRQEPGSPPRDGLHHGPLCLGEPAPFWRGVLSTPDSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MESTPSFLKGTPTWEKTAPENGIVRQEPGSPPRDGLHHGPLCLGEPAPFWRGVLSTPDSW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LPPGFPQGPKDMLPLVEGEGPQNGERKVNWLGSKEGLRWKEAMLTHPLAFCGPACPPRCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LPPGFPQGPKDMLPLVEGEGPQNGERKVNWLGSKEGLRWKEAMLTHPLAFCGPACPPRCG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 PLMPEHSGGHLKSDPVAFRPWHCPFLLETKILERAPFWVPTCLPPYLVSGLPPEHPCDWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 PLMPEHSGGHLKSDPVAFRPWHCPFLLETKILERAPFWVPTCLPPYLVSGLPPEHPCDWP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LTPHPWVYSGGQPKVPSAFSLGSKGFYYKDPSIPRLAKEPLAAAEPGLFGLNSGGHLQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LTPHPWVYSGGQPKVPSAFSLGSKGFYYKDPSIPRLAKEPLAAAEPGLFGLNSGGHLQRA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 GEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 NLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGDLGPCGKCQEGLEGGASGASEPSE :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: CCDS60 NLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 GLQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GLQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 GPGSGPDSRLSTGLAKHLLSGLGDRLCRLLRREREALAWAQREGQGPAVTEDSPGIPRCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GPGSGPDSRLSTGLAKHLLSGLGDRLCRLLRREREALAWAQREGQGPAVTEDSPGIPRCC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SRCHHGLFNTHWRCPRCSHRLCVACGRVAGTGRAREKAGFQEQSAEECTQEAGHAACSLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SRCHHGLFNTHWRCPRCSHRLCVACGRVAGTGRAREKAGFQEQSAEECTQEAGHAACSLM 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 LTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWAPGDAGQQKESTQKTPPTPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWAPGDAGQQKESTQKTPPTPQP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 SCNGDTHRTKSIKEETPDSAETPAEDRAGRGPLPCPSLCELLASTAVKLCLGHERIHMAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SCNGDTHRTKSIKEETPDSAETPAEDRAGRGPLPCPSLCELLASTAVKLCLGHERIHMAF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 APVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGPGLRKGLGLPLSPVRPRLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 APVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGPGLRKGLGLPLSPVRPRLP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 PPGALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNLWGTEALGALGGQVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 PPGALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNLWGTEALGALGGQVQA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 LSPLGPPQPSSLGSTTFWEGFSWPELRPKSDEGSVLLLHRALGDEDTSRVENLAASLPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LSPLGPPQPSSLGSTTFWEGFSWPELRPKSDEGSVLLLHRALGDEDTSRVENLAASLPLP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 EYCALHGKLNLASYLPPGLALRPLEPQLWAAYGVSPHRGHLGTKNLCVEVADLVSILVHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EYCALHGKLNLASYLPPGLALRPLEPQLWAAYGVSPHRGHLGTKNLCVEVADLVSILVHA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB3 DTPLPAWHRAQKDFLSGLDGEGLWSPGSQVSTVWHVFRAQDAQRIRRFLQMVCPAGAGAL :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 DTPLPAWHRAQKDFLSGLDGEGLWSPGSQVSTVWHVFRAQDAQRIRRFLQMV-------- 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KB3 EPGAPGSCYLDAGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHF ::::::::::::: CCDS60 -----------------------------------------------QGLVSTVSVTQHF 1080 1150 1160 1170 1180 pF1KB3 LSPETSALSAQLCHQGPSLPPDCHLLYAQMDWAVFQAVKVAVGTLQEAK ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LSPETSALSAQLCHQGPSLPPDCHLLYAQMDWAVFQAVKVAVGTLQEAK 1090 1100 1110 1120 1130 1189 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:43:31 2016 done: Thu Nov 3 12:43:32 2016 Total Scan time: 6.180 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]