FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3288, 744 aa 1>>>pF1KB3288 744 - 744 aa - 744 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 15.2999+/-0.000579; mu= -22.7985+/- 0.036 mean_var=809.5810+/-168.595, 0's: 0 Z-trim(123.0): 637 B-trim: 1378 in 1/60 Lambda= 0.045076 statistics sampled from 41380 (42113) to 41380 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.744), E-opt: 0.2 (0.494), width: 16 Scan time: 15.300 The best scores are: opt bits E(85289) NP_065084 (OMIM: 120251) collagen alpha-1(VIII) ch ( 744) 5593 379.5 2.6e-104 NP_001841 (OMIM: 120251) collagen alpha-1(VIII) ch ( 744) 5593 379.5 2.6e-104 NP_005193 (OMIM: 120252,136800,609140) collagen al ( 703) 2644 187.7 1.4e-46 XP_005270534 (OMIM: 120252,136800,609140) PREDICTE ( 780) 2644 187.8 1.5e-46 NP_001281276 (OMIM: 120252,136800,609140) collagen ( 638) 2624 186.4 3.1e-46 XP_016865738 (OMIM: 120110,156500) PREDICTED: coll ( 680) 1942 142.1 7.3e-33 XP_011533735 (OMIM: 120110,156500) PREDICTED: coll ( 680) 1942 142.1 7.3e-33 XP_016865737 (OMIM: 120110,156500) PREDICTED: coll ( 680) 1942 142.1 7.3e-33 XP_006715396 (OMIM: 120110,156500) PREDICTED: coll ( 680) 1942 142.1 7.3e-33 NP_000484 (OMIM: 120110,156500) collagen alpha-1(X ( 680) 1942 142.1 7.3e-33 XP_011533734 (OMIM: 120110,156500) PREDICTED: coll ( 680) 1942 142.1 7.3e-33 XP_016884751 (OMIM: 301050,303630) PREDICTED: coll (1289) 1629 122.0 1.5e-26 XP_016884750 (OMIM: 301050,303630) PREDICTED: coll (1330) 1629 122.0 1.6e-26 XP_016869755 (OMIM: 120215,130000) PREDICTED: coll (1715) 1631 122.3 1.7e-26 NP_001265003 (OMIM: 120215,130000) collagen alpha- (1838) 1631 122.3 1.8e-26 NP_000084 (OMIM: 120215,130000) collagen alpha-1(V (1838) 1631 122.3 1.8e-26 NP_000486 (OMIM: 301050,303630) collagen alpha-5(I (1685) 1629 122.1 1.8e-26 XP_016884749 (OMIM: 301050,303630) PREDICTED: coll (1690) 1629 122.1 1.8e-26 NP_203699 (OMIM: 301050,303630) collagen alpha-5(I (1691) 1629 122.1 1.8e-26 XP_016884748 (OMIM: 301050,303630) PREDICTED: coll (1693) 1629 122.1 1.8e-26 XP_011529151 (OMIM: 301050,303630) PREDICTED: coll (1696) 1629 122.1 1.8e-26 XP_016855826 (OMIM: 120280,154780,228520,603932,60 (1323) 1613 121.0 3.2e-26 XP_016855825 (OMIM: 120280,154780,228520,603932,60 (1515) 1613 121.0 3.5e-26 NP_542197 (OMIM: 120280,154780,228520,603932,60484 (1690) 1613 121.1 3.8e-26 NP_001177638 (OMIM: 120280,154780,228520,603932,60 (1767) 1613 121.1 3.9e-26 NP_001845 (OMIM: 120280,154780,228520,603932,60484 (1806) 1613 121.1 4e-26 NP_542196 (OMIM: 120280,154780,228520,603932,60484 (1818) 1613 121.1 4e-26 XP_016855824 (OMIM: 120280,154780,228520,603932,60 (1855) 1613 121.1 4e-26 XP_016855823 (OMIM: 120280,154780,228520,603932,60 (1857) 1613 121.1 4e-26 XP_016884752 (OMIM: 301050,303630) PREDICTED: coll (1136) 1586 119.2 9.7e-26 NP_000081 (OMIM: 120180,130020,130050) collagen al (1466) 1577 118.7 1.7e-25 XP_011515191 (OMIM: 610026) PREDICTED: collagen al (1058) 1539 116.1 7.7e-25 XP_016868641 (OMIM: 610026) PREDICTED: collagen al (1264) 1539 116.2 8.7e-25 XP_011515189 (OMIM: 610026) PREDICTED: collagen al (1264) 1539 116.2 8.7e-25 XP_016868640 (OMIM: 610026) PREDICTED: collagen al (1552) 1539 116.2 1e-24 XP_016868639 (OMIM: 610026) PREDICTED: collagen al (1564) 1539 116.2 1e-24 XP_011515188 (OMIM: 610026) PREDICTED: collagen al (1577) 1539 116.3 1e-24 XP_011515187 (OMIM: 610026) PREDICTED: collagen al (1588) 1539 116.3 1e-24 XP_011515186 (OMIM: 610026) PREDICTED: collagen al (1593) 1539 116.3 1e-24 XP_011515185 (OMIM: 610026) PREDICTED: collagen al (1606) 1539 116.3 1e-24 XP_016865740 (OMIM: 120290,184840,215150,277610,60 (1342) 1534 115.9 1.1e-24 XP_011512604 (OMIM: 120290,184840,215150,277610,60 (1365) 1534 115.9 1.1e-24 XP_011512602 (OMIM: 120290,184840,215150,277610,60 (1438) 1534 115.9 1.2e-24 XP_011512601 (OMIM: 120290,184840,215150,277610,60 (1498) 1534 115.9 1.2e-24 NP_542410 (OMIM: 120290,184840,215150,277610,60186 (1629) 1534 115.9 1.3e-24 NP_542412 (OMIM: 120290,184840,215150,277610,60186 (1650) 1534 115.9 1.3e-24 XP_016865739 (OMIM: 120290,184840,215150,277610,60 (1736) 1534 116.0 1.4e-24 NP_542411 (OMIM: 120290,184840,215150,277610,60186 (1736) 1534 116.0 1.4e-24 XP_011526344 (OMIM: 120216) PREDICTED: collagen al (1744) 1520 115.1 2.6e-24 NP_056534 (OMIM: 120216) collagen alpha-3(V) chain (1745) 1520 115.1 2.6e-24 >>NP_065084 (OMIM: 120251) collagen alpha-1(VIII) chain (744 aa) initn: 5593 init1: 5593 opt: 5593 Z-score: 1993.6 bits: 379.5 E(85289): 2.6e-104 Smith-Waterman score: 5593; 100.0% identity (100.0% similar) in 744 aa overlap (1-744:1-744) 10 20 30 40 50 60 pF1KB3 MAVLPGPLQLLGVLLTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MAVLPGPLQLLGVLLTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 MPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 GPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 IGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 IGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 GDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 IGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 IGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 HGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 HGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 YGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 YGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 YYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 YYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPS 670 680 690 700 710 720 730 740 pF1KB3 EQAAGLYAGQYVHSSFSGYLLYPM :::::::::::::::::::::::: NP_065 EQAAGLYAGQYVHSSFSGYLLYPM 730 740 >>NP_001841 (OMIM: 120251) collagen alpha-1(VIII) chain (744 aa) initn: 5593 init1: 5593 opt: 5593 Z-score: 1993.6 bits: 379.5 E(85289): 2.6e-104 Smith-Waterman score: 5593; 100.0% identity (100.0% similar) in 744 aa overlap (1-744:1-744) 10 20 30 40 50 60 pF1KB3 MAVLPGPLQLLGVLLTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAVLPGPLQLLGVLLTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 MPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 GPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 IGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 GDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 IGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 HGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 YGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 YYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPS 670 680 690 700 710 720 730 740 pF1KB3 EQAAGLYAGQYVHSSFSGYLLYPM :::::::::::::::::::::::: NP_001 EQAAGLYAGQYVHSSFSGYLLYPM 730 740 >>NP_005193 (OMIM: 120252,136800,609140) collagen alpha- (703 aa) initn: 5240 init1: 2003 opt: 2644 Z-score: 957.5 bits: 187.7 E(85289): 1.4e-46 Smith-Waterman score: 2644; 57.2% identity (71.1% similar) in 671 aa overlap (88-743:42-702) 60 70 80 90 100 110 pF1KB3 VPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGK--EIPLA- .:.. .: .: .: ::. :.:: NP_005 LLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGP-VGPPFREGKGQYLEMPLPL 20 30 40 50 60 70 120 130 140 150 160 pF1KB3 ---SLRGEQGPRGEPGPRGPPGPPGLPGH---GIPGIKGKPGPQGYPG---VGKPGMPGM .:.:: :: :.:::::::::::.::. : ::..:.::: : :: .:: : ::. NP_005 LPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGL 80 90 100 110 120 130 170 180 190 200 210 220 pF1KB3 PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDR ::: : :.:: .:: : .:. : : ::: : ::: :. ::::. :.:: :: .:. NP_005 PGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEP 140 150 160 170 180 190 230 240 250 260 270 280 pF1KB3 GPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGP ::.: ::: : :: :::.: :.:: ::. : : :::: : :.::::. :.:: : NP_005 GPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGD 200 210 220 230 240 250 290 300 310 320 330 340 pF1KB3 LGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPP :. : :: :::.: :. : .::::. :.: :: :.:: : :.::: :: ::: NP_005 KGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGE---PGTRGPP 260 270 280 290 300 350 360 370 380 390 400 pF1KB3 GL--P-GIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMG :: : : : ::.:::::::: .:::: :: ::: : : :: :: : : ::.:: : NP_005 GLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAG 310 320 330 340 350 360 410 420 430 440 450 460 pF1KB3 PPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKG :: : ::::::.: :: : :: .:. : .:. :::: :: : :: .: ::: :::: NP_005 LPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKG 370 380 390 400 410 420 470 480 490 500 510 520 pF1KB3 EAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPG : : : :: ::: : :: ::. :.::. ::.:: ::::. ::.::::: :.:: ::::: NP_005 EPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPG 430 440 450 460 470 480 530 540 550 560 570 580 pF1KB3 LPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQG :::::: :.::.:: :::: ::. : : : ::::::::::: :... : : NP_005 LPGPPGEGRAGEPGTAGPTGPPGVPGS--P-GITGPPGPPGPPGPPGAPGAFDETGIA-G 490 500 510 520 530 540 590 600 610 620 630 640 pF1KB3 EYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNG .::. : :..:. .. . : . :. ::::: ::.::: : ::::.. :::: NP_005 LHLPN-G-GVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNG 550 560 570 580 590 600 650 660 670 680 690 700 pF1KB3 RQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASG ...::: :::::: : :::::::::: :: ::::::.::: :. :::::::::.:::::: NP_005 HSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASG 610 620 630 640 650 660 710 720 730 740 pF1KB3 SAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM .::: :::.:.:..::::.:: :::. .:.::::::.:: : NP_005 GAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT 670 680 690 700 >>XP_005270534 (OMIM: 120252,136800,609140) PREDICTED: c (780 aa) initn: 5240 init1: 2003 opt: 2644 Z-score: 957.0 bits: 187.8 E(85289): 1.5e-46 Smith-Waterman score: 2644; 57.2% identity (71.1% similar) in 671 aa overlap (88-743:119-779) 60 70 80 90 100 110 pF1KB3 VPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGK--EIPLA- .:.. .: .: .: ::. :.:: XP_005 LLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGP-VGPPFREGKGQYLEMPLPL 90 100 110 120 130 140 120 130 140 150 160 pF1KB3 ---SLRGEQGPRGEPGPRGPPGPPGLPGH---GIPGIKGKPGPQGYPG---VGKPGMPGM .:.:: :: :.:::::::::::.::. : ::..:.::: : :: .:: : ::. XP_005 LPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGL 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB3 PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDR ::: : :.:: .:: : .:. : : ::: : ::: :. ::::. :.:: :: .:. XP_005 PGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEP 210 220 230 240 250 260 230 240 250 260 270 280 pF1KB3 GPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGP ::.: ::: : :: :::.: :.:: ::. : : :::: : :.::::. :.:: : XP_005 GPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGD 270 280 290 300 310 320 290 300 310 320 330 340 pF1KB3 LGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPP :. : :: :::.: :. : .::::. :.: :: :.:: : :.::: :: ::: XP_005 KGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGE---PGTRGPP 330 340 350 360 370 380 350 360 370 380 390 400 pF1KB3 GL--P-GIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMG :: : : : ::.:::::::: .:::: :: ::: : : :: :: : : ::.:: : XP_005 GLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAG 390 400 410 420 430 440 410 420 430 440 450 460 pF1KB3 PPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKG :: : ::::::.: :: : :: .:. : .:. :::: :: : :: .: ::: :::: XP_005 LPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKG 450 460 470 480 490 500 470 480 490 500 510 520 pF1KB3 EAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPG : : : :: ::: : :: ::. :.::. ::.:: ::::. ::.::::: :.:: ::::: XP_005 EPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPG 510 520 530 540 550 560 530 540 550 560 570 580 pF1KB3 LPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQG :::::: :.::.:: :::: ::. : : : ::::::::::: :... : : XP_005 LPGPPGEGRAGEPGTAGPTGPPGVPGS--P-GITGPPGPPGPPGPPGAPGAFDETGIA-G 570 580 590 600 610 620 590 600 610 620 630 640 pF1KB3 EYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNG .::. : :..:. .. . : . :. ::::: ::.::: : ::::.. :::: XP_005 LHLPN-G-GVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNG 630 640 650 660 670 650 660 670 680 690 700 pF1KB3 RQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASG ...::: :::::: : :::::::::: :: ::::::.::: :. :::::::::.:::::: XP_005 HSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASG 680 690 700 710 720 730 710 720 730 740 pF1KB3 SAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM .::: :::.:.:..::::.:: :::. .:.::::::.:: : XP_005 GAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT 740 750 760 770 780 >>NP_001281276 (OMIM: 120252,136800,609140) collagen alp (638 aa) initn: 5232 init1: 1995 opt: 2624 Z-score: 951.0 bits: 186.4 E(85289): 3.1e-46 Smith-Waterman score: 2624; 58.6% identity (72.1% similar) in 642 aa overlap (111-743:6-637) 90 100 110 120 130 140 pF1KB3 KEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGH .:. .:.:: :: :.:::::::::::.::. NP_001 MPLPLLPM-DLKGEPGPPGKPGPRGPPGPPGFPGK 10 20 30 150 160 170 180 190 pF1KB3 ---GIPGIKGKPGPQGYPG---VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG : ::..:.::: : :: .:: : ::.::: : :.:: .:: : .:. : : :: NP_001 PGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPG 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB3 PQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVK : : ::: :. ::::. :.:: :: .:. ::.: ::: : :: :::.: :.:: ::. NP_001 PPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAP 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB3 GPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPG : : :::: : :.::::. :.:: : :. : :: :::.: :. : .::::. : NP_001 GQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB3 IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGL--P-GIGKPGFPGPKGDRGMGGVPGAL .: :: :.:: : :.::: :: ::::: : : : ::.:::::::: .:::: : NP_001 VGVPGAAGLPGPQGPSGAKGE---PGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLL 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB3 GPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEP : ::: : : :: :: : : ::.:: : :: : ::::::.: :: : :: .:. NP_001 GDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQ 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB3 GLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQ : .:. :::: :: : :: .: ::: ::::: : : :: ::: : :: ::. :.::. NP_001 GPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQP 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB3 GLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALG ::.:: ::::. ::.::::: :.:: ::::::::::: :.::.:: :::: ::. : NP_001 GLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPG 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB3 PQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGP : : ::::::::::: :... : : .::. : :..:. .. . : . NP_001 ITG-P--PGPPGPPGPPGAPGAFDETGIA-GLHLPN-G-GVEGAVLGKGGKPQFGLGELS 460 470 480 490 500 620 630 640 650 660 670 pF1KB3 AYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHCKG :. ::::: ::.::: : ::::.. ::::...::: :::::: : :::::::::: :: NP_001 AHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKG 510 520 530 540 550 560 680 690 700 710 720 730 pF1KB3 GNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAGQY ::::::.::: :. :::::::::.::::::.::: :::.:.:..::::.:: :::. .: NP_001 TNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEY 570 580 590 600 610 620 740 pF1KB3 VHSSFSGYLLYPM .::::::.:: : NP_001 IHSSFSGFLLCPT 630 >>XP_016865738 (OMIM: 120110,156500) PREDICTED: collagen (680 aa) initn: 1884 init1: 1884 opt: 1942 Z-score: 711.0 bits: 142.1 E(85289): 7.3e-33 Smith-Waterman score: 2509; 52.7% identity (67.7% similar) in 706 aa overlap (57-744:4-680) 30 40 50 60 70 80 pF1KB3 AGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHL :.: . :.. .:. : . :...: .. XP_016 MLPQIPFLLLVSLNLVHG-----VFYAERY-QM 10 20 90 100 110 120 130 140 pF1KB3 PQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGP---PGP---PGLPGH : .: : . . .: : .: .::::: : ::: :: ::: :: ::. XP_016 PTGIKGPLPNTKT-QFFIPYTIKSKGIA-VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY 30 40 50 60 70 80 150 160 170 180 190 pF1KB3 GIPGIKGKPGPQGYPG---VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQG : ::..:.:: : :: :::::.::.::: :: .: : ::..:: :.:::.: XP_016 GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGK------PGERGPYGPKGDVGPAGLPGPRG 90 100 110 120 130 200 210 220 230 240 250 pF1KB3 PPGPHGLPGI------GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAP :::: :.:: :::: : : :::.: : :: :: :. : ::. :.: :: : XP_016 PPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRP 140 150 160 170 180 190 260 270 280 290 300 310 pF1KB3 GVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG : .: :: .:: :: : ::::: : .: :: : : : ::: :: :: :: ::::: XP_016 GERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGP---PGPQGPPG 200 210 220 230 240 250 320 330 340 350 360 pF1KB3 I--P-GIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVP : :::::: : :::::.:: :: : ::. :::: ::.::::.:: ::.:: .:.: XP_016 ERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLP 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB3 GALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPK :. : .::.:: : :: : : :: : :: : ::. :.:::::: : .:: : :: : XP_016 GGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAK 320 330 340 350 360 370 430 440 450 460 470 480 pF1KB3 GEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIP :: : : ::::. :. : : .: :: ::::. : : ::::: : : :: :: XP_016 GERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHN 380 390 400 410 420 430 490 500 510 520 530 540 pF1KB3 GDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPG :. : .: ::::: :: :: : ::.:: ::.:: ::::: ::. :. : :::: :: XP_016 GEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPG 440 450 460 470 480 490 550 560 570 580 590 600 pF1KB3 ALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKN : .:.:::::::::::::: :::: :. :... : :. :..: . XP_016 PRGHSGEPGLPGPPGPPGPPGQ-AVMPEGFIKAGQR-PSLS-GTPLVS------ANQGVT 500 510 520 530 540 610 620 630 640 650 660 pF1KB3 GGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVH : : . :::. :. .: .:.:. :.:.::: .:.:.:.::::::..::.:::.:::: XP_016 GMP---VSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVH 550 560 570 580 590 600 670 680 690 700 710 720 pF1KB3 CKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYA :: .:::.:.::. ::::::::: ::.::::::::.. : .:.:.::.:. .. :::. XP_016 VKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYS 610 620 630 640 650 660 730 740 pF1KB3 GQYVHSSFSGYLLYPM ..::::::::.:. :: XP_016 SEYVHSSFSGFLVAPM 670 680 >>XP_011533735 (OMIM: 120110,156500) PREDICTED: collagen (680 aa) initn: 1884 init1: 1884 opt: 1942 Z-score: 711.0 bits: 142.1 E(85289): 7.3e-33 Smith-Waterman score: 2509; 52.7% identity (67.7% similar) in 706 aa overlap (57-744:4-680) 30 40 50 60 70 80 pF1KB3 AGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHL :.: . :.. .:. : . :...: .. XP_011 MLPQIPFLLLVSLNLVHG-----VFYAERY-QM 10 20 90 100 110 120 130 140 pF1KB3 PQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGP---PGP---PGLPGH : .: : . . .: : .: .::::: : ::: :: ::: :: ::. XP_011 PTGIKGPLPNTKT-QFFIPYTIKSKGIA-VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY 30 40 50 60 70 80 150 160 170 180 190 pF1KB3 GIPGIKGKPGPQGYPG---VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQG : ::..:.:: : :: :::::.::.::: :: .: : ::..:: :.:::.: XP_011 GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGK------PGERGPYGPKGDVGPAGLPGPRG 90 100 110 120 130 200 210 220 230 240 250 pF1KB3 PPGPHGLPGI------GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAP :::: :.:: :::: : : :::.: : :: :: :. : ::. :.: :: : XP_011 PPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRP 140 150 160 170 180 190 260 270 280 290 300 310 pF1KB3 GVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG : .: :: .:: :: : ::::: : .: :: : : : ::: :: :: :: ::::: XP_011 GERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGP---PGPQGPPG 200 210 220 230 240 250 320 330 340 350 360 pF1KB3 I--P-GIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVP : :::::: : :::::.:: :: : ::. :::: ::.::::.:: ::.:: .:.: XP_011 ERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLP 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB3 GALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPK :. : .::.:: : :: : : :: : :: : ::. :.:::::: : .:: : :: : XP_011 GGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAK 320 330 340 350 360 370 430 440 450 460 470 480 pF1KB3 GEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIP :: : : ::::. :. : : .: :: ::::. : : ::::: : : :: :: XP_011 GERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHN 380 390 400 410 420 430 490 500 510 520 530 540 pF1KB3 GDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPG :. : .: ::::: :: :: : ::.:: ::.:: ::::: ::. :. : :::: :: XP_011 GEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPG 440 450 460 470 480 490 550 560 570 580 590 600 pF1KB3 ALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKN : .:.:::::::::::::: :::: :. :... : :. :..: . XP_011 PRGHSGEPGLPGPPGPPGPPGQ-AVMPEGFIKAGQR-PSLS-GTPLVS------ANQGVT 500 510 520 530 540 610 620 630 640 650 660 pF1KB3 GGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVH : : . :::. :. .: .:.:. :.:.::: .:.:.:.::::::..::.:::.:::: XP_011 GMP---VSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVH 550 560 570 580 590 600 670 680 690 700 710 720 pF1KB3 CKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYA :: .:::.:.::. ::::::::: ::.::::::::.. : .:.:.::.:. .. :::. XP_011 VKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYS 610 620 630 640 650 660 730 740 pF1KB3 GQYVHSSFSGYLLYPM ..::::::::.:. :: XP_011 SEYVHSSFSGFLVAPM 670 680 >>XP_016865737 (OMIM: 120110,156500) PREDICTED: collagen (680 aa) initn: 1884 init1: 1884 opt: 1942 Z-score: 711.0 bits: 142.1 E(85289): 7.3e-33 Smith-Waterman score: 2509; 52.7% identity (67.7% similar) in 706 aa overlap (57-744:4-680) 30 40 50 60 70 80 pF1KB3 AGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHL :.: . :.. .:. : . :...: .. XP_016 MLPQIPFLLLVSLNLVHG-----VFYAERY-QM 10 20 90 100 110 120 130 140 pF1KB3 PQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGP---PGP---PGLPGH : .: : . . .: : .: .::::: : ::: :: ::: :: ::. XP_016 PTGIKGPLPNTKT-QFFIPYTIKSKGIA-VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY 30 40 50 60 70 80 150 160 170 180 190 pF1KB3 GIPGIKGKPGPQGYPG---VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQG : ::..:.:: : :: :::::.::.::: :: .: : ::..:: :.:::.: XP_016 GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGK------PGERGPYGPKGDVGPAGLPGPRG 90 100 110 120 130 200 210 220 230 240 250 pF1KB3 PPGPHGLPGI------GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAP :::: :.:: :::: : : :::.: : :: :: :. : ::. :.: :: : XP_016 PPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRP 140 150 160 170 180 190 260 270 280 290 300 310 pF1KB3 GVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG : .: :: .:: :: : ::::: : .: :: : : : ::: :: :: :: ::::: XP_016 GERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGP---PGPQGPPG 200 210 220 230 240 250 320 330 340 350 360 pF1KB3 I--P-GIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVP : :::::: : :::::.:: :: : ::. :::: ::.::::.:: ::.:: .:.: XP_016 ERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLP 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB3 GALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPK :. : .::.:: : :: : : :: : :: : ::. :.:::::: : .:: : :: : XP_016 GGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAK 320 330 340 350 360 370 430 440 450 460 470 480 pF1KB3 GEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIP :: : : ::::. :. : : .: :: ::::. : : ::::: : : :: :: XP_016 GERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHN 380 390 400 410 420 430 490 500 510 520 530 540 pF1KB3 GDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPG :. : .: ::::: :: :: : ::.:: ::.:: ::::: ::. :. : :::: :: XP_016 GEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPG 440 450 460 470 480 490 550 560 570 580 590 600 pF1KB3 ALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKN : .:.:::::::::::::: :::: :. :... : :. :..: . XP_016 PRGHSGEPGLPGPPGPPGPPGQ-AVMPEGFIKAGQR-PSLS-GTPLVS------ANQGVT 500 510 520 530 540 610 620 630 640 650 660 pF1KB3 GGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVH : : . :::. :. .: .:.:. :.:.::: .:.:.:.::::::..::.:::.:::: XP_016 GMP---VSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVH 550 560 570 580 590 600 670 680 690 700 710 720 pF1KB3 CKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYA :: .:::.:.::. ::::::::: ::.::::::::.. : .:.:.::.:. .. :::. XP_016 VKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYS 610 620 630 640 650 660 730 740 pF1KB3 GQYVHSSFSGYLLYPM ..::::::::.:. :: XP_016 SEYVHSSFSGFLVAPM 670 680 >>XP_006715396 (OMIM: 120110,156500) PREDICTED: collagen (680 aa) initn: 1884 init1: 1884 opt: 1942 Z-score: 711.0 bits: 142.1 E(85289): 7.3e-33 Smith-Waterman score: 2509; 52.7% identity (67.7% similar) in 706 aa overlap (57-744:4-680) 30 40 50 60 70 80 pF1KB3 AGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHL :.: . :.. .:. : . :...: .. XP_006 MLPQIPFLLLVSLNLVHG-----VFYAERY-QM 10 20 90 100 110 120 130 140 pF1KB3 PQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGP---PGP---PGLPGH : .: : . . .: : .: .::::: : ::: :: ::: :: ::. XP_006 PTGIKGPLPNTKT-QFFIPYTIKSKGIA-VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY 30 40 50 60 70 80 150 160 170 180 190 pF1KB3 GIPGIKGKPGPQGYPG---VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQG : ::..:.:: : :: :::::.::.::: :: .: : ::..:: :.:::.: XP_006 GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGK------PGERGPYGPKGDVGPAGLPGPRG 90 100 110 120 130 200 210 220 230 240 250 pF1KB3 PPGPHGLPGI------GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAP :::: :.:: :::: : : :::.: : :: :: :. : ::. :.: :: : XP_006 PPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRP 140 150 160 170 180 190 260 270 280 290 300 310 pF1KB3 GVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG : .: :: .:: :: : ::::: : .: :: : : : ::: :: :: :: ::::: XP_006 GERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGP---PGPQGPPG 200 210 220 230 240 250 320 330 340 350 360 pF1KB3 I--P-GIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVP : :::::: : :::::.:: :: : ::. :::: ::.::::.:: ::.:: .:.: XP_006 ERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLP 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB3 GALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPK :. : .::.:: : :: : : :: : :: : ::. :.:::::: : .:: : :: : XP_006 GGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAK 320 330 340 350 360 370 430 440 450 460 470 480 pF1KB3 GEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIP :: : : ::::. :. : : .: :: ::::. : : ::::: : : :: :: XP_006 GERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHN 380 390 400 410 420 430 490 500 510 520 530 540 pF1KB3 GDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPG :. : .: ::::: :: :: : ::.:: ::.:: ::::: ::. :. : :::: :: XP_006 GEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPG 440 450 460 470 480 490 550 560 570 580 590 600 pF1KB3 ALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKN : .:.:::::::::::::: :::: :. :... : :. :..: . XP_006 PRGHSGEPGLPGPPGPPGPPGQ-AVMPEGFIKAGQR-PSLS-GTPLVS------ANQGVT 500 510 520 530 540 610 620 630 640 650 660 pF1KB3 GGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVH : : . :::. :. .: .:.:. :.:.::: .:.:.:.::::::..::.:::.:::: XP_006 GMP---VSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVH 550 560 570 580 590 600 670 680 690 700 710 720 pF1KB3 CKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYA :: .:::.:.::. ::::::::: ::.::::::::.. : .:.:.::.:. .. :::. XP_006 VKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYS 610 620 630 640 650 660 730 740 pF1KB3 GQYVHSSFSGYLLYPM ..::::::::.:. :: XP_006 SEYVHSSFSGFLVAPM 670 680 >>NP_000484 (OMIM: 120110,156500) collagen alpha-1(X) ch (680 aa) initn: 1884 init1: 1884 opt: 1942 Z-score: 711.0 bits: 142.1 E(85289): 7.3e-33 Smith-Waterman score: 2509; 52.7% identity (67.7% similar) in 706 aa overlap (57-744:4-680) 30 40 50 60 70 80 pF1KB3 AGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHL :.: . :.. .:. : . :...: .. NP_000 MLPQIPFLLLVSLNLVHG-----VFYAERY-QM 10 20 90 100 110 120 130 140 pF1KB3 PQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGP---PGP---PGLPGH : .: : . . .: : .: .::::: : ::: :: ::: :: ::. NP_000 PTGIKGPLPNTKT-QFFIPYTIKSKGIA-VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY 30 40 50 60 70 80 150 160 170 180 190 pF1KB3 GIPGIKGKPGPQGYPG---VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQG : ::..:.:: : :: :::::.::.::: :: .: : ::..:: :.:::.: NP_000 GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGK------PGERGPYGPKGDVGPAGLPGPRG 90 100 110 120 130 200 210 220 230 240 250 pF1KB3 PPGPHGLPGI------GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAP :::: :.:: :::: : : :::.: : :: :: :. : ::. :.: :: : NP_000 PPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRP 140 150 160 170 180 190 260 270 280 290 300 310 pF1KB3 GVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG : .: :: .:: :: : ::::: : .: :: : : : ::: :: :: :: ::::: NP_000 GERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGP---PGPQGPPG 200 210 220 230 240 250 320 330 340 350 360 pF1KB3 I--P-GIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVP : :::::: : :::::.:: :: : ::. :::: ::.::::.:: ::.:: .:.: NP_000 ERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLP 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB3 GALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPK :. : .::.:: : :: : : :: : :: : ::. :.:::::: : .:: : :: : NP_000 GGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAK 320 330 340 350 360 370 430 440 450 460 470 480 pF1KB3 GEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIP :: : : ::::. :. : : .: :: ::::. : : ::::: : : :: :: NP_000 GERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHN 380 390 400 410 420 430 490 500 510 520 530 540 pF1KB3 GDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPG :. : .: ::::: :: :: : ::.:: ::.:: ::::: ::. :. : :::: :: NP_000 GEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPG 440 450 460 470 480 490 550 560 570 580 590 600 pF1KB3 ALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKN : .:.:::::::::::::: :::: :. :... : :. :..: . NP_000 PRGHSGEPGLPGPPGPPGPPGQ-AVMPEGFIKAGQR-PSLS-GTPLVS------ANQGVT 500 510 520 530 540 610 620 630 640 650 660 pF1KB3 GGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVH : : . :::. :. .: .:.:. :.:.::: .:.:.:.::::::..::.:::.:::: NP_000 GMP---VSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVH 550 560 570 580 590 600 670 680 690 700 710 720 pF1KB3 CKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYA :: .:::.:.::. ::::::::: ::.::::::::.. : .:.:.::.:. .. :::. NP_000 VKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYS 610 620 630 640 650 660 730 740 pF1KB3 GQYVHSSFSGYLLYPM ..::::::::.:. :: NP_000 SEYVHSSFSGFLVAPM 670 680 744 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:54:00 2016 done: Thu Nov 3 20:54:02 2016 Total Scan time: 15.300 Total Display time: 0.200 Function used was FASTA [36.3.4 Apr, 2011]