FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3294, 950 aa 1>>>pF1KB3294 950 - 950 aa - 950 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4460+/-0.000427; mu= 11.1299+/- 0.026 mean_var=128.0949+/-25.988, 0's: 0 Z-trim(115.6): 415 B-trim: 2178 in 2/53 Lambda= 0.113320 statistics sampled from 25666 (26132) to 25666 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.306), width: 16 Scan time: 14.160 The best scores are: opt bits E(85289) NP_061723 (OMIM: 606307) protocadherin alpha-1 iso ( 950) 6178 1022.2 0 NP_113598 (OMIM: 606307) protocadherin alpha-1 iso ( 807) 5133 851.3 0 NP_061728 (OMIM: 606308) protocadherin alpha-2 iso ( 948) 5111 847.7 0 NP_061729 (OMIM: 606309) protocadherin alpha-3 iso ( 950) 5078 842.3 0 NP_061734 (OMIM: 606314) protocadherin alpha-8 iso ( 950) 5066 840.4 0 NP_061730 (OMIM: 606310) protocadherin alpha-4 iso ( 947) 5033 835.0 0 NP_061732 (OMIM: 606312) protocadherin alpha-6 iso ( 950) 5033 835.0 0 NP_061727 (OMIM: 606319) protocadherin alpha-13 is ( 950) 5009 831.1 0 NP_114063 (OMIM: 606315) protocadherin alpha-9 iso ( 950) 5006 830.6 0 NP_061725 (OMIM: 606317) protocadherin alpha-11 is ( 949) 5000 829.6 0 NP_061724 (OMIM: 606316) protocadherin alpha-10 is ( 948) 4878 809.6 0 NP_061731 (OMIM: 606311) protocadherin alpha-5 iso ( 936) 4094 681.5 5.5e-195 NP_113684 (OMIM: 606308) protocadherin alpha-2 iso ( 808) 4073 678.0 5.2e-194 NP_113683 (OMIM: 606308) protocadherin alpha-2 iso ( 824) 4073 678.0 5.3e-194 NP_113689 (OMIM: 606311) protocadherin alpha-5 iso ( 816) 4059 675.7 2.6e-193 NP_113685 (OMIM: 606309) protocadherin alpha-3 iso ( 824) 4033 671.5 4.9e-192 NP_114062 (OMIM: 606314) protocadherin alpha-8 iso ( 814) 4028 670.6 8.6e-192 NP_113688 (OMIM: 606310) protocadherin alpha-4 iso ( 798) 3998 665.7 2.5e-190 NP_114036 (OMIM: 606312) protocadherin alpha-6 iso ( 803) 3991 664.6 5.6e-190 NP_061733 (OMIM: 606313) protocadherin alpha-7 iso ( 937) 3991 664.6 6.4e-190 NP_114071 (OMIM: 606319) protocadherin alpha-13 is ( 807) 3972 661.5 4.9e-189 NP_054724 (OMIM: 606315) protocadherin alpha-9 iso ( 842) 3961 659.7 1.8e-188 NP_114067 (OMIM: 606317) protocadherin alpha-11 is ( 810) 3956 658.9 3e-188 NP_114040 (OMIM: 606313) protocadherin alpha-7 iso ( 789) 3952 658.2 4.6e-188 NP_061726 (OMIM: 606318) protocadherin alpha-12 is ( 941) 3867 644.4 8.1e-184 NP_114065 (OMIM: 606316) protocadherin alpha-10 is ( 844) 3839 639.8 1.8e-182 NP_114070 (OMIM: 606318) protocadherin alpha-12 is ( 792) 3836 639.3 2.4e-182 NP_113599 (OMIM: 606307) protocadherin alpha-1 iso ( 686) 3443 575.0 4.6e-163 NP_114037 (OMIM: 606312) protocadherin alpha-6 iso ( 686) 2577 433.4 1.9e-120 NP_114066 (OMIM: 606316) protocadherin alpha-10 is ( 685) 2563 431.1 9.3e-120 NP_002579 (OMIM: 603627) protocadherin gamma-C3 is ( 934) 2023 342.9 4.6e-93 NP_115778 (OMIM: 603627) protocadherin gamma-C3 is ( 863) 1985 336.7 3.2e-91 NP_114089 (OMIM: 606321) protocadherin alpha-C2 is ( 884) 1950 330.9 1.7e-89 NP_115265 (OMIM: 603059) protocadherin gamma-A12 i ( 820) 1925 326.8 2.7e-88 NP_003726 (OMIM: 603059) protocadherin gamma-A12 i ( 932) 1925 326.9 3e-88 NP_061736 (OMIM: 606297) protocadherin gamma-A10 i ( 936) 1918 325.7 6.7e-88 NP_114479 (OMIM: 606297) protocadherin gamma-A10 i ( 850) 1917 325.5 6.9e-88 NP_003727 (OMIM: 603058) protocadherin gamma-B4 is ( 923) 1911 324.6 1.5e-87 NP_061747 (OMIM: 606301) protocadherin gamma-B3 is ( 929) 1908 324.1 2.1e-87 NP_114476 (OMIM: 606294) protocadherin gamma-A7 is ( 817) 1904 323.4 2.9e-87 NP_061743 (OMIM: 606294) protocadherin gamma-A7 is ( 932) 1904 323.4 3.3e-87 NP_061758 (OMIM: 606341) protocadherin beta-15 pre ( 787) 1892 321.4 1.1e-86 NP_114480 (OMIM: 606298) protocadherin gamma-A11 i ( 837) 1891 321.3 1.3e-86 NP_061738 (OMIM: 606289) protocadherin gamma-A2 is ( 932) 1891 321.3 1.4e-86 NP_061737 (OMIM: 606298) protocadherin gamma-A11 i ( 935) 1891 321.3 1.4e-86 NP_114398 (OMIM: 606289) protocadherin gamma-A2 is ( 823) 1884 320.1 2.8e-86 NP_114477 (OMIM: 606295) protocadherin gamma-A8 is ( 932) 1881 319.7 4.4e-86 NP_054723 (OMIM: 606295) protocadherin gamma-A8 is ( 820) 1876 318.8 7e-86 NP_061744 (OMIM: 606296) protocadherin gamma-A9 is ( 932) 1870 317.9 1.5e-85 NP_114478 (OMIM: 606296) protocadherin gamma-A9 is ( 828) 1868 317.5 1.8e-85 >>NP_061723 (OMIM: 606307) protocadherin alpha-1 isoform (950 aa) initn: 6178 init1: 6178 opt: 6178 Z-score: 5462.9 bits: 1022.2 E(85289): 0 Smith-Waterman score: 6178; 100.0% identity (100.0% similar) in 950 aa overlap (1-950:1-950) 10 20 30 40 50 60 pF1KB3 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 850 860 870 880 890 900 910 920 930 940 950 pF1KB3 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ :::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 910 920 930 940 950 >>NP_113598 (OMIM: 606307) protocadherin alpha-1 isoform (807 aa) initn: 5133 init1: 5133 opt: 5133 Z-score: 4540.6 bits: 851.3 E(85289): 0 Smith-Waterman score: 5133; 100.0% identity (100.0% similar) in 798 aa overlap (1-798:1-798) 10 20 30 40 50 60 pF1KB3 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP :::::::::::::::::: NP_113 NTSERNEQPEANLDLSGNVSPTFEFWL 790 800 >>NP_061728 (OMIM: 606308) protocadherin alpha-2 isoform (948 aa) initn: 5112 init1: 4073 opt: 5111 Z-score: 4520.2 bits: 847.7 E(85289): 0 Smith-Waterman score: 5111; 83.3% identity (92.2% similar) in 950 aa overlap (1-950:1-948) 10 20 30 40 50 60 pF1KB3 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV :. : : : :: :: ::::::::::::::.::.::::::::::::.:::::::: ::: NP_061 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE ::::::::: : :::::::::::::::::::::::: :::::::.:.:.:::::::::: NP_061 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL :.:::::::::.: . : .::::::.::::.:::.:::::.::::.: :: :..: : NP_061 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP :..:.::::.:: : : : :::::: :..:::.::::::::: :::..:: ::::::: : NP_061 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG : :.::.:.:::.:::::::. ::::::::: :.:.:.:. : .: :: :: .: :: NP_061 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR ::: ::::::.::::::: :.:::.: ::.:::. .:..:.:::.::...::: ::: NP_061 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV :.: :.::::::::::::::.::.::::: :::::::::::::::::::::::::::.:. NP_061 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR ::::::::::::::::::. ::.:::::::::::::::::::::::::::::::::::: NP_061 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::::::::::::::::::::::.:::::::::::::::::::::.:::::::::::: NP_061 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD :::::::::::::::::::::::::::::.: . :::::::: :::::::::::::::: NP_061 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT :::::::::::: ..:.::::::::::::::::::.::::: :.::::::::::::::: NP_061 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA :::::::::::::::::::::: ::.:: ::.::::::::::::::::::::::.::::: NP_061 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL ::::::::::: .:::::::::::.:::: ::::::::::.: :::::::::::.:: . NP_061 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP ...:... :. . :.:::::::::::::::::::::::::::::::::::::::::: NP_061 DSAEEKQLSES--EYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 790 800 810 820 830 850 860 870 880 890 900 pF1KB3 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 840 850 860 870 880 890 910 920 930 940 950 pF1KB3 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ :::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 900 910 920 930 940 >>NP_061729 (OMIM: 606309) protocadherin alpha-3 isoform (950 aa) initn: 5078 init1: 5078 opt: 5078 Z-score: 4491.0 bits: 842.3 E(85289): 0 Smith-Waterman score: 5078; 81.8% identity (92.5% similar) in 950 aa overlap (1-950:1-950) 10 20 30 40 50 60 pF1KB3 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV :.:: : ::. ::: :::::: ::::::::::. :::::::::::.:::::::::::: NP_061 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE ::::::::: : :::::::::::::::::::::::: :::::::::.:.:::::::::: NP_061 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL :.::::::: ::: . .:: ::: .::: .:::.:::::.:.::::.:. ..::.: NP_061 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP ::. .:: ::: : :.: :.::.::. .::.:: ::::::: ::..: ::::::::::: NP_061 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG :....:.:.:::.. :::::.:.::.: ::::: ....::.. .: :: ::..: .: NP_061 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR .: . ..:.::.:::::::.:.:::.::::.:: ::....:.:::.:::.. :: ::. NP_061 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV ::.:::::::::.:::::::.:::::::: ::::::::::::::::::::: :::::.:. NP_061 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR ::::::::::::::::::: :::::::::::::::.: :::::::::::::::::::::: NP_061 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: NP_061 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD :::::::::::::::::::::::::: ::::: ::::::::: :::::::::::::::: NP_061 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT :::::::::::::..::::::::::::::::::::.:::.: :.::::::::::::.:: NP_061 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA ::::::::::::::::::::.::.:..::::::::::::::.:::::::::::::::::: NP_061 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL ::::.::::: :::::::::::.:::: ::::.:::::.:: ::::::::::.: : NP_061 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP . .:.:. ....:::..:::::::::::::::::::::::::::::::::::::::::: NP_061 ISRDREEKQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 850 860 870 880 890 900 910 920 930 940 950 pF1KB3 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ :::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 910 920 930 940 950 >>NP_061734 (OMIM: 606314) protocadherin alpha-8 isoform (950 aa) initn: 5066 init1: 5066 opt: 5066 Z-score: 4480.4 bits: 840.4 E(85289): 0 Smith-Waterman score: 5066; 81.1% identity (91.8% similar) in 950 aa overlap (1-950:1-950) 10 20 30 40 50 60 pF1KB3 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV : . :: ::. ::: :::::::.:::::::::.::::::::::::.:::::::::::: NP_061 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE ::::::::: :::::::.:::::::::::::::::: :::::::::.:.:::::::::. NP_061 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL :.:::.:::::::: ..: .:. :::. .::::.:::.:::.:::..::: :: ::: : NP_061 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP ::..... .: . : ::: ::::..: ::.::::::::::: :::.::.:::::::::: NP_061 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG :.:. :.:...:.. ::: : ::::: :::.:: . .::.: . . ..:..: ..: NP_061 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR :: . .::.:. . :.: . :.::: :::..:: :::..:: :::.::.:.::: ::.: NP_061 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV ::: ..::::::.:.: ::::::::::::::::::::::::::::::::::::::: .:. NP_061 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR ::::::::::::::::::: .::::::::::::::::::::::::::::::::::::::: NP_061 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA ::::::::::::::::::::::.::.:.:::.:::::::::::::::::::::::::::: NP_061 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD :::::::::::::::::::::::::: :::::: ::.:.:::: :::::::::::::::: NP_061 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT :::::::::::::::.. ::::::::::::::::::::::: :.::::::::::::::: NP_061 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA ::::::::::::::::::::: :.:: ::::::::::::::::::::::::::::::::: NP_061 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL ::::. ::::. ::::::::::.:::: :::. :::::.::::::::::::: : :.: NP_061 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP .. . .:. . :.: . .:::::::::::::::::::::::::::::::::::::::::: NP_061 GSVDVGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 850 860 870 880 890 900 910 920 930 940 950 pF1KB3 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ :::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 910 920 930 940 950 >>NP_061730 (OMIM: 606310) protocadherin alpha-4 isoform (947 aa) initn: 3999 init1: 3999 opt: 5033 Z-score: 4451.2 bits: 835.0 E(85289): 0 Smith-Waterman score: 5033; 81.7% identity (92.1% similar) in 950 aa overlap (1-950:1-947) 10 20 30 40 50 60 pF1KB3 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV : :: .: .: ::: ::::::::.:.::::::. :::::::::::.:::::::::::: NP_061 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE ::::::::: . :::::::::::::::::::::::. :::::::::.:.:::::::::. NP_061 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL :.:.::::::::: . .. . : ::: :.::::.:::.::::: :::::: :::..:::: NP_061 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP . .::: :.: : ::: :::::.::. :.::::::::::: :::.:::::::.::::: NP_061 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG ::...:.:.:::.. ::::: ::::: :::.::..:.::.. :: ... ::..: .: NP_061 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR .: . .:.::.::::: :...:::. :.:.::.:.:.: : :::.:.: :: :::: NP_061 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV :::::.::::::.:::.: :.:: ::::: ::::::::::::::::::::::::::.:. NP_061 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::: NP_061 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::::::::::::::::::::::.:::::::::::::::::::::::::::::.:::: NP_061 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD :::::::::::::::::::::::::::::.::: :::::::: ::.::::::::::::: NP_061 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT :::::::::::::..::::::::::::::::::::.:::.: :.::::::::::::::: NP_061 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA :::::::::::::::::::::: ::..::.:::::::::::::::::::::::::::::: NP_061 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL ::::. ::::: .:::::::::::.:::: ::::: ::::.:::::::::::::.: : NP_061 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL-P-- 730 740 750 760 770 790 800 810 820 830 840 pF1KB3 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP .. .:..: ... . ..:::::::::::::::::::::::::::::::::::::::::: NP_061 DSRDREDQLQTTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 780 790 800 810 820 830 850 860 870 880 890 900 pF1KB3 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 840 850 860 870 880 890 910 920 930 940 950 pF1KB3 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ :::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 900 910 920 930 940 >>NP_061732 (OMIM: 606312) protocadherin alpha-6 isoform (950 aa) initn: 5033 init1: 5033 opt: 5033 Z-score: 4451.2 bits: 835.0 E(85289): 0 Smith-Waterman score: 5033; 80.9% identity (92.1% similar) in 950 aa overlap (1-950:1-950) 10 20 30 40 50 60 pF1KB3 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV :::. . :: . ::: :::::::.:::::::::.::::::::::::.:::::::::::: NP_061 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE :::::.::: ..:::::::::::::::::::::::: :::::::::.:.:::::::::. NP_061 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL :.:.:::::::.: .:: ..: :::: .: ::.:::.:::.:.:..::: :: :.::.: NP_061 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP ::. ... .:.. : :.: :::::.: .:.::::::::::: :::.::.:::::::::: NP_061 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG :.:. :.:...:.. ::: : ::::: :::.:: . .::.: .. . ..:..: ..: NP_061 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR :: . .::.:. . :.: . :.::: :::..:: :::..:: :::.::.:.::: ::.: NP_061 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV ::: ..::::::.:.: ::::::::.::: :::::::::::::::::::::::::::.:. NP_061 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR ::::::::::::::::::: .::::::.:::::::::::::::::::::::::::::::: NP_061 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::::::::::::::::::::::.:.:::::::::::::::::::::::::::::::: NP_061 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD ::::::::::::::::::::::::::::::::: ::::::::: .:::.::::::::::: NP_061 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT ::::::::::::: :..::.::::::::::::::::::::: :.::::::::::::::: NP_061 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: NP_061 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL ::::.:::::: . :::::::::.:::: ::::::::::.::::: :::::::.::: NP_061 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP . :. . : : ...:::::::::::::::::::::::::::::::::::::::::: NP_061 IMMGKAENQDLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 850 860 870 880 890 900 910 920 930 940 950 pF1KB3 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ :::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 910 920 930 940 950 >>NP_061727 (OMIM: 606319) protocadherin alpha-13 isofor (950 aa) initn: 5009 init1: 5009 opt: 5009 Z-score: 4430.0 bits: 831.1 E(85289): 0 Smith-Waterman score: 5009; 81.2% identity (91.2% similar) in 950 aa overlap (1-950:1-950) 10 20 30 40 50 60 pF1KB3 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV :. : .:: :.::::::.:::::.::::::::.::::::::::::.:::::::::::: NP_061 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE ::::::::: : :::::::::::::::::::::::: :::::::::.:.:::::::::: NP_061 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL :::.:::::::.: .. :.: ::: ..:::..::.:::::.:. ::: :.:.:::.: NP_061 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP :.. : : .:: : ::: ::::: : :::::.::::::: :::.::::.:::::::: NP_061 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG : :.::.: .::.. ::::: :::.: :.:.::..:.:: . . : .. ..: NP_061 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR ::: :::.:: : :::.:.:::::. ::..:: .::.::::::::::...::: :::: NP_061 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV ::. :..::::.:::::::.::::::.: ::::::::::.::::::::::::::::.:. NP_061 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR ::::::::::::::::::: ::: :::::::::::::::::::::::::::::::::::. NP_061 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::. NP_061 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD ::::::::::::::::::::::::::.: .:.. :.::::.:: :::::::::::::::: NP_061 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT :::::::::::: :: ::::::::::::::::::: :::.: ..::::::::::::::: NP_061 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA ::::::.:::::::::.::::::.:..::::::::::::::::::::::::::::::::: NP_061 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL ::::.:::::: .::::::::::: :::: ::::: ::::.::: :::::::::.: : : NP_061 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP ...: . : : . . .:::::::::::::::::::::::::::::::::::::::::: NP_061 GSAEGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 850 860 870 880 890 900 910 920 930 940 950 pF1KB3 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ :::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 910 920 930 940 950 >>NP_114063 (OMIM: 606315) protocadherin alpha-9 isoform (950 aa) initn: 5006 init1: 5006 opt: 5006 Z-score: 4427.4 bits: 830.6 E(85289): 0 Smith-Waterman score: 5006; 80.6% identity (91.7% similar) in 950 aa overlap (1-950:1-950) 10 20 30 40 50 60 pF1KB3 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV :..: :: .. ::: ::.:: : :::::::::.::::.:::::::.:::::::::::: NP_114 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE ::::.. :: . :::::::::::::::::::::::: :::::::::.:.:::::::::. NP_114 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL :.::::::::::: . .. .:: ::: :.::::.:::.::::: :::::: :::..:: : NP_114 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP :: .:.. : : : ::: ::::::::::::::::::::::: :::.::::::: ::::: NP_114 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG .::...: :.: :... :::: :::: :::.::....::.: .: ::. ::..: :: NP_114 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR : .: ..:.::.....: :.::::: ::...:: .::.:.:::::::.:.. .: .:.. NP_114 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV ::: :.::::::.: : :. ::::::::: ::::::::::.::::::::: ::::::.:. NP_114 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: NP_114 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA ::::::::::::::::::.:::.::.:::::::::::::::::::::::::::::::::: NP_114 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD ::::::::::::::::::::::::::.::. :: :::::.: : :::: ::.:::::::: NP_114 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT ::::::::::::: ...: ::::::::::::::::.:::.: : ::::::::::::::: NP_114 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA :::::::::::::::::.:::::::..:::..:::::::::::::::::::::::::::. NP_114 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL ::::. :::: .:::::::::::.:::: ::::::::::.:: ::::::::::::: NP_114 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP ...::. .: :. : .:.:::::::::::::::::::::::::::::::::::::::::: NP_114 GSTERTGEPSASSDSTGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 850 860 870 880 890 900 910 920 930 940 950 pF1KB3 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ :::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 910 920 930 940 950 >>NP_061725 (OMIM: 606317) protocadherin alpha-11 isofor (949 aa) initn: 4995 init1: 3729 opt: 5000 Z-score: 4422.1 bits: 829.6 E(85289): 0 Smith-Waterman score: 5000; 81.9% identity (91.7% similar) in 948 aa overlap (3-950:4-949) 10 20 30 40 50 pF1KB3 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAEL :.::: ::. : :::::: :::::::::::. :::::::::::.::::::::::: NP_061 MFGFQRRG-LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAEL 10 20 30 40 50 60 70 80 90 100 110 pF1KB3 VPRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHV : :::::::::: :::::::::::::::::::::::: :::::::::.:.::::::::: NP_061 VQRLFRVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 EVKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFS .:.::::::::::: ::: ..: ::. .::::.:::.:::: :::::: :: ..::: NP_061 NVEVKDINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 LDVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNA :: .. . : : : :.: ::::.::::.::::::::::::: :::.::. ::::::: NP_061 LDSPTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDND 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 PLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSS : ::.. :.: :.:..:. ::: :::.: ::::::::..:. : :. . .. : .:... NP_061 PEFDKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNN 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 GEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPI ::.:. :::::.: :.:.:.:.:::.:::..:: : :..::.:::.::.::::: ::. NP_061 GEVRVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPV 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 REDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLS :::: :::::::.:::::::.:::::::: ::::::::::::::::::::::::::.. NP_061 REDAQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVW 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 VYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 AYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB3 RDADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARD :::::::::::::::::::.:.::::.::::::::::::::::::::::::::::::::: NP_061 RDADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB3 AGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDA ::::::.::::::::::::::::::::: ..:.. :::..:::: ::::::::::::::: NP_061 AGVPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDA 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB3 DSGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPAL ::::::::::::::::::.:::::::::::::::::.::::: :.:::::::::::::: NP_061 DSGYNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPAL 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 TATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYT ::::::::::::::::::::::. .:.:.:::::::::::::::::.::::::::::::: NP_061 TATATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYT 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB3 ALRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPS :: :. ::::: .::::::::: :.:::: :::::::::: :::::::::::::.: . NP_061 ALWWSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLG 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB3 LNTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQW :: :..:. : . . :.::::::::::::::::::::::::::::::::::::::::: NP_061 LNKEEEGERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQW 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB3 PTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 PTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISI 840 850 860 870 880 890 900 910 920 930 940 950 pF1KB3 RQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 RQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 900 910 920 930 940 950 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:45:05 2016 done: Thu Nov 3 12:45:07 2016 Total Scan time: 14.160 Total Display time: 0.400 Function used was FASTA [36.3.4 Apr, 2011]