Result of FASTA (omim) for
pF1KB3307
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3307, 718 aa
1>>>pF1KB3307 718 - 718 aa - 718 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5731+/-0.000335; mu= 18.5011+/- 0.021
mean_var=67.3801+/-14.040, 0's: 0 Z-trim(114.7): 20 B-trim: 0 in 0/53
Lambda= 0.156246
statistics sampled from 24724 (24743) to 24724 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.29), width: 16
Scan time: 10.980
The best scores are: opt bits E(85289)
NP_079426 (OMIM: 612805,615918) threonine--tRNA li ( 718) 4901 1113.9 0
XP_006711618 (OMIM: 612805,615918) PREDICTED: thre ( 684) 3956 900.9 0
XP_006711619 (OMIM: 612805,615918) PREDICTED: thre ( 669) 2832 647.5 4.9e-185
NP_001258825 (OMIM: 612805,615918) threonine--tRNA ( 588) 2609 597.2 5.9e-170
NP_001258824 (OMIM: 612805,615918) threonine--tRNA ( 636) 2605 596.3 1.2e-169
XP_016857883 (OMIM: 612805,615918) PREDICTED: thre ( 635) 1887 434.5 6.2e-121
XP_016857884 (OMIM: 612805,615918) PREDICTED: thre ( 602) 1740 401.4 5.6e-111
NP_001245366 (OMIM: 187790) threonine--tRNA ligase ( 723) 1416 328.4 6.3e-89
NP_689508 (OMIM: 187790) threonine--tRNA ligase, c ( 723) 1416 328.4 6.3e-89
NP_001245367 (OMIM: 187790) threonine--tRNA ligase ( 756) 1416 328.4 6.6e-89
NP_059142 (OMIM: 611845) 39S ribosomal protein L39 ( 338) 162 45.5 0.00041
XP_006724089 (OMIM: 611845) PREDICTED: 39S ribosom ( 353) 162 45.5 0.00042
NP_542984 (OMIM: 611845) 39S ribosomal protein L39 ( 353) 162 45.5 0.00042
XP_011527953 (OMIM: 611845) PREDICTED: 39S ribosom ( 296) 157 44.4 0.00079
>>NP_079426 (OMIM: 612805,615918) threonine--tRNA ligase (718 aa)
initn: 4901 init1: 4901 opt: 4901 Z-score: 5963.1 bits: 1113.9 E(85289): 0
Smith-Waterman score: 4901; 100.0% identity (100.0% similar) in 718 aa overlap (1-718:1-718)
10 20 30 40 50 60
pF1KB3 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEPRT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 IKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLRFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSELPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 TFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSELPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVDLC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QGPHLRHTGQIGGLKLLSNSSSLWRSSGAPETLQRVSGISFPTTELLRVWEAWREEAELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QGPHLRHTGQIGGLKLLSNSSSLWRSSGAPETLQRVSGISFPTTELLRVWEAWREEAELR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 DHRRIGKEQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFSTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DHRRIGKEQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFSTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 LWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 RSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 SVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 DVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQAGALERPVLIHRAVLGSVERLLGVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQAGALERPVLIHRAVLGSVERLLGVLA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 ESCGGKWPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ESCGGKWPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRA
610 620 630 640 650 660
670 680 690 700 710
pF1KB3 QLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEIF
670 680 690 700 710
>>XP_006711618 (OMIM: 612805,615918) PREDICTED: threonin (684 aa)
initn: 3956 init1: 3956 opt: 3956 Z-score: 4812.2 bits: 900.9 E(85289): 0
Smith-Waterman score: 4598; 95.3% identity (95.3% similar) in 718 aa overlap (1-718:1-684)
10 20 30 40 50 60
pF1KB3 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEPRT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLRFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSELPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSELPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVDLC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QGPHLRHTGQIGGLKLLSNSSSLWRSSGAPETLQRVSGISFPTTELLRVWEAWREEAELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QGPHLRHTGQIGGLKLLSNSSSLWRSSGAPETLQRVSGISFPTTELLRVWEAWREEAELR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 DHRRIGKEQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFSTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DHRRIGKEQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFSTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 LWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 RSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 SVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 DVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQAGALERPVLIHRAVLGSVERLLGVLA
:::::::::::::::::::::::::::::::::
XP_006 DVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKG---------------------------
550 560 570
610 620 630 640 650 660
pF1KB3 ESCGGKWPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 -------PLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRA
580 590 600 610 620
670 680 690 700 710
pF1KB3 QLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEIF
630 640 650 660 670 680
>>XP_006711619 (OMIM: 612805,615918) PREDICTED: threonin (669 aa)
initn: 2832 init1: 2832 opt: 2832 Z-score: 3443.0 bits: 647.5 E(85289): 4.9e-185
Smith-Waterman score: 4463; 93.2% identity (93.2% similar) in 718 aa overlap (1-718:1-669)
10 20 30 40 50 60
pF1KB3 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEPRT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLRFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSELPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSELPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVDLC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QGPHLRHTGQIGGLKLLSNSSSLWRSSGAPETLQRVSGISFPTTELLRVWEAWREEAELR
::::::::::::::::::
XP_006 QGPHLRHTGQIGGLKLLS------------------------------------------
250
310 320 330 340 350 360
pF1KB3 DHRRIGKEQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFSTK
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 -------EQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFSTK
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB3 LWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRP
320 330 340 350 360 370
430 440 450 460 470 480
pF1KB3 RSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLR
380 390 400 410 420 430
490 500 510 520 530 540
pF1KB3 SVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKI
440 450 460 470 480 490
550 560 570 580 590 600
pF1KB3 DVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQAGALERPVLIHRAVLGSVERLLGVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQAGALERPVLIHRAVLGSVERLLGVLA
500 510 520 530 540 550
610 620 630 640 650 660
pF1KB3 ESCGGKWPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESCGGKWPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRA
560 570 580 590 600 610
670 680 690 700 710
pF1KB3 QLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEIF
620 630 640 650 660
>>NP_001258825 (OMIM: 612805,615918) threonine--tRNA lig (588 aa)
initn: 2609 init1: 2609 opt: 2609 Z-score: 3172.2 bits: 597.2 E(85289): 5.9e-170
Smith-Waterman score: 3741; 81.9% identity (81.9% similar) in 718 aa overlap (1-718:1-588)
10 20 30 40 50 60
pF1KB3 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEPRT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLRFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSELPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSELPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVDLC
::::::::::::::::::::::::::::::
NP_001 LERICQELTAAARPFRRLEASRDQLRQLFK------------------------------
190 200 210
250 260 270 280 290 300
pF1KB3 QGPHLRHTGQIGGLKLLSNSSSLWRSSGAPETLQRVSGISFPTTELLRVWEAWREEAELR
NP_001 ------------------------------------------------------------
310 320 330 340 350 360
pF1KB3 DHRRIGKEQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFSTK
::::::::::::::::::::
NP_001 ----------------------------------------AEYAHRGFSEVKTPTLFSTK
220 230
370 380 390 400 410 420
pF1KB3 LWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRP
240 250 260 270 280 290
430 440 450 460 470 480
pF1KB3 RSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLR
300 310 320 330 340 350
490 500 510 520 530 540
pF1KB3 SVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKI
360 370 380 390 400 410
550 560 570 580 590 600
pF1KB3 DVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQAGALERPVLIHRAVLGSVERLLGVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQAGALERPVLIHRAVLGSVERLLGVLA
420 430 440 450 460 470
610 620 630 640 650 660
pF1KB3 ESCGGKWPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESCGGKWPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRA
480 490 500 510 520 530
670 680 690 700 710
pF1KB3 QLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEIF
540 550 560 570 580
>>NP_001258824 (OMIM: 612805,615918) threonine--tRNA lig (636 aa)
initn: 2605 init1: 2605 opt: 2605 Z-score: 3166.8 bits: 596.3 E(85289): 1.2e-169
Smith-Waterman score: 4169; 88.6% identity (88.6% similar) in 718 aa overlap (1-718:1-636)
10 20 30 40 50 60
pF1KB3 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEPRT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLRFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSELPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSELPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVDLC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QGPHLRHTGQIGGLKLLSNSSSLWRSSGAPETLQRVSGISFPTTELLRVWEAWREEAELR
::::::::::::::::::
NP_001 QGPHLRHTGQIGGLKLLS------------------------------------------
250
310 320 330 340 350 360
pF1KB3 DHRRIGKEQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFSTK
::::::::::::::::::::
NP_001 ----------------------------------------AEYAHRGFSEVKTPTLFSTK
260 270
370 380 390 400 410 420
pF1KB3 LWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRP
280 290 300 310 320 330
430 440 450 460 470 480
pF1KB3 RSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLR
340 350 360 370 380 390
490 500 510 520 530 540
pF1KB3 SVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKI
400 410 420 430 440 450
550 560 570 580 590 600
pF1KB3 DVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQAGALERPVLIHRAVLGSVERLLGVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQAGALERPVLIHRAVLGSVERLLGVLA
460 470 480 490 500 510
610 620 630 640 650 660
pF1KB3 ESCGGKWPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESCGGKWPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRA
520 530 540 550 560 570
670 680 690 700 710
pF1KB3 QLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEIF
580 590 600 610 620 630
>>XP_016857883 (OMIM: 612805,615918) PREDICTED: threonin (635 aa)
initn: 2449 init1: 1887 opt: 1887 Z-score: 2292.1 bits: 434.5 E(85289): 6.2e-121
Smith-Waterman score: 4160; 88.4% identity (88.4% similar) in 718 aa overlap (1-718:1-635)
10 20 30 40 50 60
pF1KB3 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEPRT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLRFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSELPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSELPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVDLC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QGPHLRHTGQIGGLKLLSNSSSLWRSSGAPETLQRVSGISFPTTELLRVWEAWREEAELR
::::::::::::::::::
XP_016 QGPHLRHTGQIGGLKLLS------------------------------------------
250
310 320 330 340 350 360
pF1KB3 DHRRIGKEQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFSTK
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -------EQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFSTK
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB3 LWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRP
320 330 340 350 360 370
430 440 450 460 470 480
pF1KB3 RSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLR
380 390 400 410 420 430
490 500 510 520 530 540
pF1KB3 SVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKI
440 450 460 470 480 490
550 560 570 580 590 600
pF1KB3 DVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQAGALERPVLIHRAVLGSVERLLGVLA
:::::::::::::::::::::::::::::::::
XP_016 DVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKG---------------------------
500 510 520
610 620 630 640 650 660
pF1KB3 ESCGGKWPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -------PLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRA
530 540 550 560 570
670 680 690 700 710
pF1KB3 QLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEIF
580 590 600 610 620 630
>>XP_016857884 (OMIM: 612805,615918) PREDICTED: threonin (602 aa)
initn: 2449 init1: 1740 opt: 1740 Z-score: 2113.4 bits: 401.4 E(85289): 5.6e-111
Smith-Waterman score: 3866; 83.8% identity (83.8% similar) in 718 aa overlap (1-718:1-602)
10 20 30 40 50 60
pF1KB3 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEPRT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLRFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSELPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSELPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVDLC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QGPHLRHTGQIGGLKLLSNSSSLWRSSGAPETLQRVSGISFPTTELLRVWEAWREEAELR
::::::::::::::::::
XP_016 QGPHLRHTGQIGGLKLLS------------------------------------------
250
310 320 330 340 350 360
pF1KB3 DHRRIGKEQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFSTK
::::::::::::::::::::
XP_016 ----------------------------------------AEYAHRGFSEVKTPTLFSTK
260 270
370 380 390 400 410 420
pF1KB3 LWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRP
280 290 300 310 320 330
430 440 450 460 470 480
pF1KB3 RSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLR
340 350 360 370 380 390
490 500 510 520 530 540
pF1KB3 SVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKI
400 410 420 430 440 450
550 560 570 580 590 600
pF1KB3 DVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQAGALERPVLIHRAVLGSVERLLGVLA
:::::::::::::::::::::::::::::::::
XP_016 DVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKG---------------------------
460 470 480 490
610 620 630 640 650 660
pF1KB3 ESCGGKWPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -------PLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRA
500 510 520 530 540
670 680 690 700 710
pF1KB3 QLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEIF
550 560 570 580 590 600
>>NP_001245366 (OMIM: 187790) threonine--tRNA ligase, cy (723 aa)
initn: 2658 init1: 919 opt: 1416 Z-score: 1717.4 bits: 328.4 E(85289): 6.3e-89
Smith-Waterman score: 2631; 54.1% identity (79.9% similar) in 691 aa overlap (29-718:51-723)
10 20 30 40 50
pF1KB3 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEP
:... :: ... : : . . :: :.:.
NP_001 GAGEEKQKEGGKKKNKEGSGDGGRAELNPWPEYIYTRLEMYNILKAEHDSILAEKAEKDS
30 40 50 60 70 80
60 70 80 90 100 110
pF1KB3 RTIKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLR
. ::..:: :...:: .:.:::::.: ::. :::..: :.::. .::.:::: : :.
NP_001 KPIKVTLPDGKQVDAESWKTTPYQIACGISQGLADNTVIAKVNNVVWDLDRPLEEDCTLE
90 100 110 120 130 140
120 130 140 150 160 170
pF1KB3 FLTFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSEL
.: :.. :..::.::::.:..: : :. :. :: :: : :::.:..: .: . ....
NP_001 LLKFEDEEAQAVYWHSSAHIMGEAMERVYGGCLCYGPPIENGFYYDMYL-EEGGVSSNDF
150 160 170 180 190
180 190 200 210 220 230
pF1KB3 PVLERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVD
:: .:... . :.:::.... : .:: : :: ....:::. ::.::: :: :.:
NP_001 SSLEALCKKIIKEKQAFERLEVKKETLLAMFKYNKFKCRILNEKVNTPTTTVYRCGPLID
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB3 LCQGPHLRHTGQIGGLKLLSNSSSLWRSSGAPETLQRVSGISFPTTELLRVWEAWREEAE
::.:::.::::.: .::. .:::. :.... :::::. ::::: ..:. :: ..:::.
NP_001 LCRGPHVRHTGKIKALKIHKNSSTYWEGKADMETLQRIYGISFPDPKMLKEWEKFQEEAK
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB3 LRDHRRIGKEQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFS
::::.::..:::.::::::::::::::.:. .::::. :::.:: .:::.:: ::..:.
NP_001 NRDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFN
320 330 340 350 360 370
360 370 380 390 400 410
pF1KB3 TKLWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAH
..:: ::::.::.:.::. . . .::::::::.::::: :
NP_001 SRLWMTSGHWQHYSENMFSFEVE-----------------KELFALKPMNCPGHCLMFDH
380 390 400 410 420
420 430 440 450 460 470
pF1KB3 RPRSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDF
::::::::::::::::.::: : ::.: ::::.: ::::::::::. .:.: ::..::::
NP_001 RPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDF
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB3 LRSVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGP
::.::.:.::::.: ::::: :::: .:::::. :...:.:::: :.:::::::::::
NP_001 LRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB3 KIDVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQAGA-LERPVLIHRAVLGSVERLLG
:::....::.:: :::.:::::::::.::.: : .. : .:::..:::.::::::...
NP_001 KIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIA
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB3 VLAESCGGKWPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRI
.:.:. :::::.:::: ::.:.::: .:::....:... : ...:.: : : ::...:
NP_001 ILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB3 RRAQLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEI
: ::::.::: .:::.::. . :::::::::. :: . :...:: .:.. : .:::
NP_001 RNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEE
670 680 690 700 710 720
pF1KB3 F
:
NP_001 F
>>NP_689508 (OMIM: 187790) threonine--tRNA ligase, cytop (723 aa)
initn: 2658 init1: 919 opt: 1416 Z-score: 1717.4 bits: 328.4 E(85289): 6.3e-89
Smith-Waterman score: 2631; 54.1% identity (79.9% similar) in 691 aa overlap (29-718:51-723)
10 20 30 40 50
pF1KB3 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEP
:... :: ... : : . . :: :.:.
NP_689 GAGEEKQKEGGKKKNKEGSGDGGRAELNPWPEYIYTRLEMYNILKAEHDSILAEKAEKDS
30 40 50 60 70 80
60 70 80 90 100 110
pF1KB3 RTIKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDLERPLETDSDLR
. ::..:: :...:: .:.:::::.: ::. :::..: :.::. .::.:::: : :.
NP_689 KPIKVTLPDGKQVDAESWKTTPYQIACGISQGLADNTVIAKVNNVVWDLDRPLEEDCTLE
90 100 110 120 130 140
120 130 140 150 160 170
pF1KB3 FLTFDSPEGKAVFWHSSTHVLGAAAEQFLGAVLCRGPSTEYGFYHDFFLGKERTIRGSEL
.: :.. :..::.::::.:..: : :. :. :: :: : :::.:..: .: . ....
NP_689 LLKFEDEEAQAVYWHSSAHIMGEAMERVYGGCLCYGPPIENGFYYDMYL-EEGGVSSNDF
150 160 170 180 190
180 190 200 210 220 230
pF1KB3 PVLERICQELTAAARPFRRLEASRDQLRQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVD
:: .:... . :.:::.... : .:: : :: ....:::. ::.::: :: :.:
NP_689 SSLEALCKKIIKEKQAFERLEVKKETLLAMFKYNKFKCRILNEKVNTPTTTVYRCGPLID
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB3 LCQGPHLRHTGQIGGLKLLSNSSSLWRSSGAPETLQRVSGISFPTTELLRVWEAWREEAE
::.:::.::::.: .::. .:::. :.... :::::. ::::: ..:. :: ..:::.
NP_689 LCRGPHVRHTGKIKALKIHKNSSTYWEGKADMETLQRIYGISFPDPKMLKEWEKFQEEAK
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB3 LRDHRRIGKEQELFFFHELSPGSCFFLPRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFS
::::.::..:::.::::::::::::::.:. .::::. :::.:: .:::.:: ::..:.
NP_689 NRDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFN
320 330 340 350 360 370
360 370 380 390 400 410
pF1KB3 TKLWEQSGHWEHYQEDMFAVQPPGSDRPPSSQSDDSTRHITDTLALKPMNCPAHCLMFAH
..:: ::::.::.:.::. . . .::::::::.::::: :
NP_689 SRLWMTSGHWQHYSENMFSFEVE-----------------KELFALKPMNCPGHCLMFDH
380 390 400 410 420
420 430 440 450 460 470
pF1KB3 RPRSWRELPLRLADFGALHRAEASGGLGGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDF
::::::::::::::::.::: : ::.: ::::.: ::::::::::. .:.: ::..::::
NP_689 RPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDF
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB3 LRSVYAVLGFSFRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGP
::.::.:.::::.: ::::: :::: .:::::. :...:.:::: :.:::::::::::
NP_689 LRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB3 KIDVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQAGA-LERPVLIHRAVLGSVERLLG
:::....::.:: :::.:::::::::.::.: : .. : .:::..:::.::::::...
NP_689 KIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIA
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB3 VLAESCGGKWPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRI
.:.:. :::::.:::: ::.:.::: .:::....:... : ...:.: : : ::...:
NP_689 ILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB3 RRAQLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEI
: ::::.::: .:::.::. . :::::::::. :: . :...:: .:.. : .:::
NP_689 RNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEE
670 680 690 700 710 720
pF1KB3 F
:
NP_689 F
>>NP_001245367 (OMIM: 187790) threonine--tRNA ligase, cy (756 aa)
initn: 2639 init1: 919 opt: 1416 Z-score: 1717.1 bits: 328.4 E(85289): 6.6e-89
Smith-Waterman score: 2561; 51.8% identity (76.2% similar) in 724 aa overlap (29-718:51-756)
10 20 30 40 50
pF1KB3 MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRLASMAQKEP
:... :: ... : : . . :: :.:.
NP_001 GAGEEKQKEGGKKKNKEGSGDGGRAELNPWPEYIYTRLEMYNILKAEHDSILAEKAEKDS
30 40 50 60 70 80
60 70 80 90
pF1KB3 RTIKISLPGGQKIDAVAWNTTPYQLARQISST----------------------------
. ::..:: :...:: .:.:::::.: :: :
NP_001 KPIKVTLPDGKQVDAESWKTTPYQIACGISHTASCKNLSSLASLLASVAIPSSGMPWPPL
90 100 110 120 130 140
100 110 120 130 140
pF1KB3 -----LADTAVAAQVNGEPYDLERPLETDSDLRFLTFDSPEGKAVFWHSSTHVLGAAAEQ
:::..: :.::. .::.:::: : :..: :.. :..::.::::.:..: : :.
NP_001 FFLQGLADNTVIAKVNNVVWDLDRPLEEDCTLELLKFEDEEAQAVYWHSSAHIMGEAMER
150 160 170 180 190 200
150 160 170 180 190 200
pF1KB3 FLGAVLCRGPSTEYGFYHDFFLGKERTIRGSELPVLERICQELTAAARPFRRLEASRDQL
:. :: :: : :::.:..: .: . .... :: .:... . :.:::.... :
NP_001 VYGGCLCYGPPIENGFYYDMYL-EEGGVSSNDFSSLEALCKKIIKEKQAFERLEVKKETL
210 220 230 240 250
210 220 230 240 250 260
pF1KB3 RQLFKDNPFKLHLIEEKVTGPTATVYGCGTLVDLCQGPHLRHTGQIGGLKLLSNSSSLWR
.:: : :: ....:::. ::.::: :: :.:::.:::.::::.: .::. .:::. :.
NP_001 LAMFKYNKFKCRILNEKVNTPTTTVYRCGPLIDLCRGPHVRHTGKIKALKIHKNSSTYWE
260 270 280 290 300 310
270 280 290 300 310 320
pF1KB3 SSGAPETLQRVSGISFPTTELLRVWEAWREEAELRDHRRIGKEQELFFFHELSPGSCFFL
... :::::. ::::: ..:. :: ..:::. ::::.::..:::.:::::::::::::
NP_001 GKADMETLQRIYGISFPDPKMLKEWEKFQEEAKNRDHRKIGRDQELYFFHELSPGSCFFL
320 330 340 350 360 370
330 340 350 360 370 380
pF1KB3 PRGTRVYNALVAFIRAEYAHRGFSEVKTPTLFSTKLWEQSGHWEHYQEDMFAVQPPGSDR
:.:. .::::. :::.:: .:::.:: ::..:...:: ::::.::.:.::. .
NP_001 PKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVE----
380 390 400 410 420 430
390 400 410 420 430 440
pF1KB3 PPSSQSDDSTRHITDTLALKPMNCPAHCLMFAHRPRSWRELPLRLADFGALHRAEASGGL
. .::::::::.::::: :::::::::::::::::.::: : ::.:
NP_001 -------------KELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGAL
440 450 460 470 480
450 460 470 480 490 500
pF1KB3 GGLTRLRCFQQDDAHIFCTTDQLEAEIQSCLDFLRSVYAVLGFSFRLALSTRPSGFLGDP
::::.: ::::::::::. .:.: ::..::::::.::.:.::::.: ::::: ::::
NP_001 TGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDI
490 500 510 520 530 540
510 520 530 540 550 560
pF1KB3 CLWDQAEQVLKQALKEFGEPWDLNSGDGAFYGPKIDVHLHDALGRPHQCGTIQLDFQLPL
.:::::. :...:.:::: :.::::::::::::::....::.:: :::.:::::::::.
NP_001 EVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPI
550 560 570 580 590 600
570 580 590 600 610 620
pF1KB3 RFDLQYKGQAGA-LERPVLIHRAVLGSVERLLGVLAESCGGKWPLWLSPFQVVVIPVGSE
::.: : .. : .:::..:::.::::::....:.:. :::::.:::: ::.:.:::
NP_001 RFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPT
610 620 630 640 650 660
630 640 650 660 670 680
pF1KB3 QEEYAKEAQQSLRAAGLVSDLDADSGLTLSRRIRRAQLAHYNFQFVVGQKEQSKRTVNIR
.:::....:... : ...:.: : : ::...:: ::::.::: .:::.::. . :::::
NP_001 CDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIR
670 680 690 700 710 720
690 700 710
pF1KB3 TRDNRRLGEWDLPEAVQRLVELQNTRVPNAEEIF
::::. :: . :...:: .:.. : .::: :
NP_001 TRDNKVHGERTISETIERLQQLKEFRSKQAEEEF
730 740 750
718 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 20:55:54 2016 done: Thu Nov 3 20:55:56 2016
Total Scan time: 10.980 Total Display time: 0.170
Function used was FASTA [36.3.4 Apr, 2011]