FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3314, 709 aa 1>>>pF1KB3314 709 - 709 aa - 709 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7820+/-0.000495; mu= 4.0666+/- 0.031 mean_var=203.9078+/-41.593, 0's: 0 Z-trim(114.2): 229 B-trim: 0 in 0/54 Lambda= 0.089817 statistics sampled from 23684 (23913) to 23684 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.28), width: 16 Scan time: 12.020 The best scores are: opt bits E(85289) NP_001177988 (OMIM: 602987) calcium/calmodulin-dep ( 709) 4611 611.1 4.7e-174 NP_001308984 (OMIM: 602987) calcium/calmodulin-dep ( 709) 4611 611.1 4.7e-174 XP_016867756 (OMIM: 602987) PREDICTED: calcium/cal ( 709) 4611 611.1 4.7e-174 NP_001177986 (OMIM: 602987) calcium/calmodulin-dep ( 709) 4611 611.1 4.7e-174 XP_016867754 (OMIM: 602987) PREDICTED: calcium/cal ( 749) 4352 577.6 6.2e-164 NP_001177987 (OMIM: 602987) calcium/calmodulin-dep ( 769) 4352 577.6 6.4e-164 XP_016867753 (OMIM: 602987) PREDICTED: calcium/cal ( 804) 4352 577.6 6.6e-164 NP_001308985 (OMIM: 602987) calcium/calmodulin-dep ( 634) 4078 542.0 2.7e-153 NP_005011 (OMIM: 602987) calcium/calmodulin-depend ( 634) 4078 542.0 2.7e-153 NP_001177985 (OMIM: 602987) calcium/calmodulin-dep ( 634) 4078 542.0 2.7e-153 NP_001308986 (OMIM: 602987) calcium/calmodulin-dep ( 634) 4078 542.0 2.7e-153 NP_001308987 (OMIM: 602987) calcium/calmodulin-dep ( 694) 3819 508.5 3.6e-143 XP_016867755 (OMIM: 602987) PREDICTED: calcium/cal ( 729) 3819 508.5 3.8e-143 NP_001308988 (OMIM: 602987) calcium/calmodulin-dep ( 769) 3819 508.5 3.9e-143 XP_016859791 (OMIM: 171890) PREDICTED: calcium/cal ( 529) 2367 320.2 1.3e-86 NP_001245242 (OMIM: 171890) calcium/calmodulin-dep ( 519) 2366 320.1 1.4e-86 XP_016859785 (OMIM: 171890) PREDICTED: calcium/cal ( 545) 2364 319.9 1.7e-86 XP_016859784 (OMIM: 171890) PREDICTED: calcium/cal ( 545) 2364 319.9 1.7e-86 XP_016859786 (OMIM: 171890) PREDICTED: calcium/cal ( 545) 2364 319.9 1.7e-86 XP_016859787 (OMIM: 171890) PREDICTED: calcium/cal ( 545) 2364 319.9 1.7e-86 NP_005010 (OMIM: 171890) calcium/calmodulin-depend ( 545) 2364 319.9 1.7e-86 NP_001245241 (OMIM: 171890) calcium/calmodulin-dep ( 549) 2364 319.9 1.7e-86 XP_016859789 (OMIM: 171890) PREDICTED: calcium/cal ( 535) 2363 319.7 1.8e-86 NP_001003683 (OMIM: 171890) calcium/calmodulin-dep ( 535) 2363 319.7 1.8e-86 XP_016859788 (OMIM: 171890) PREDICTED: calcium/cal ( 535) 2363 319.7 1.8e-86 XP_016859790 (OMIM: 171890) PREDICTED: calcium/cal ( 535) 2363 319.7 1.8e-86 XP_011509627 (OMIM: 171890) PREDICTED: calcium/cal ( 570) 2357 319.0 3.3e-86 XP_011509626 (OMIM: 171890) PREDICTED: calcium/cal ( 553) 2354 318.6 4.2e-86 XP_011509625 (OMIM: 171890) PREDICTED: calcium/cal ( 567) 2354 318.6 4.3e-86 XP_016859783 (OMIM: 171890) PREDICTED: calcium/cal ( 586) 2354 318.6 4.4e-86 NP_001245243 (OMIM: 171890) calcium/calmodulin-dep ( 501) 2166 294.2 8.5e-79 XP_011509628 (OMIM: 171890) PREDICTED: calcium/cal ( 552) 2157 293.0 2e-78 XP_016874921 (OMIM: 171891) PREDICTED: calcium/cal ( 501) 1984 270.6 1.1e-71 NP_001159447 (OMIM: 171891) calcium/calmodulin-dep ( 516) 1984 270.6 1.1e-71 NP_000915 (OMIM: 171891) calcium/calmodulin-depend ( 536) 1978 269.8 1.9e-71 XP_011536758 (OMIM: 171891) PREDICTED: calcium/cal ( 537) 1977 269.7 2.1e-71 NP_001275698 (OMIM: 171891) calcium/calmodulin-dep ( 495) 1967 268.4 4.8e-71 XP_016874922 (OMIM: 171891) PREDICTED: calcium/cal ( 495) 1967 268.4 4.8e-71 NP_001302463 (OMIM: 171891) calcium/calmodulin-dep ( 399) 1513 209.5 2.1e-53 NP_001275697 (OMIM: 171891) calcium/calmodulin-dep ( 399) 1513 209.5 2.1e-53 NP_001302464 (OMIM: 171891) calcium/calmodulin-dep ( 332) 1254 175.9 2.3e-43 XP_016869027 (OMIM: 171885) PREDICTED: high affini ( 448) 583 89.0 4.3e-17 NP_002594 (OMIM: 171885) high affinity cAMP-specif ( 456) 583 89.0 4.4e-17 XP_011515842 (OMIM: 171885) PREDICTED: high affini ( 456) 583 89.0 4.4e-17 NP_001229247 (OMIM: 171885) high affinity cAMP-spe ( 482) 583 89.0 4.6e-17 XP_016873400 (OMIM: 602047) PREDICTED: cGMP-inhibi (1074) 577 88.5 1.5e-16 XP_016866230 (OMIM: 604645) PREDICTED: cAMP-specif ( 343) 558 85.7 3.3e-16 NP_061818 (OMIM: 604645) cAMP-specific 3',5'-cycli ( 450) 558 85.8 4.1e-16 XP_011534057 (OMIM: 604645) PREDICTED: cAMP-specif ( 489) 558 85.8 4.4e-16 XP_005266988 (OMIM: 604645) PREDICTED: cAMP-specif ( 502) 558 85.8 4.5e-16 >>NP_001177988 (OMIM: 602987) calcium/calmodulin-depende (709 aa) initn: 4611 init1: 4611 opt: 4611 Z-score: 3245.8 bits: 611.1 E(85289): 4.7e-174 Smith-Waterman score: 4611; 100.0% identity (100.0% similar) in 709 aa overlap (1-709:1-709) 10 20 30 40 50 60 pF1KB3 MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLR 610 620 630 640 650 660 670 680 690 700 pF1KB3 HFKRPAYASSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFKRPAYASSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK 670 680 690 700 >>NP_001308984 (OMIM: 602987) calcium/calmodulin-depende (709 aa) initn: 4611 init1: 4611 opt: 4611 Z-score: 3245.8 bits: 611.1 E(85289): 4.7e-174 Smith-Waterman score: 4611; 100.0% identity (100.0% similar) in 709 aa overlap (1-709:1-709) 10 20 30 40 50 60 pF1KB3 MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLR 610 620 630 640 650 660 670 680 690 700 pF1KB3 HFKRPAYASSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFKRPAYASSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK 670 680 690 700 >>XP_016867756 (OMIM: 602987) PREDICTED: calcium/calmodu (709 aa) initn: 4611 init1: 4611 opt: 4611 Z-score: 3245.8 bits: 611.1 E(85289): 4.7e-174 Smith-Waterman score: 4611; 100.0% identity (100.0% similar) in 709 aa overlap (1-709:1-709) 10 20 30 40 50 60 pF1KB3 MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLR 610 620 630 640 650 660 670 680 690 700 pF1KB3 HFKRPAYASSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HFKRPAYASSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK 670 680 690 700 >>NP_001177986 (OMIM: 602987) calcium/calmodulin-depende (709 aa) initn: 4611 init1: 4611 opt: 4611 Z-score: 3245.8 bits: 611.1 E(85289): 4.7e-174 Smith-Waterman score: 4611; 100.0% identity (100.0% similar) in 709 aa overlap (1-709:1-709) 10 20 30 40 50 60 pF1KB3 MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLR 610 620 630 640 650 660 670 680 690 700 pF1KB3 HFKRPAYASSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFKRPAYASSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK 670 680 690 700 >>XP_016867754 (OMIM: 602987) PREDICTED: calcium/calmodu (749 aa) initn: 4352 init1: 4352 opt: 4352 Z-score: 3064.1 bits: 577.6 E(85289): 6.2e-164 Smith-Waterman score: 4352; 99.9% identity (99.9% similar) in 671 aa overlap (39-709:79-749) 10 20 30 40 50 60 pF1KB3 EEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVDLKKNLEYA ::: :::::::::::::::::::::::::: XP_016 PRPTIVHDPRPPEEILADELPQLDSPEVLVKTSFRLRSLVKQLERGEASVVDLKKNLEYA 50 60 70 80 90 100 70 80 90 100 110 120 pF1KB3 ATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRRSDEKPRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRRSDEKPRFK 110 120 130 140 150 160 130 140 150 160 170 180 pF1KB3 SIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEASGDHALKFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEASGDHALKFI 170 180 190 200 210 220 190 200 210 220 230 240 pF1KB3 FYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKTG 230 240 250 260 270 280 250 260 270 280 290 300 pF1KB3 VANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRL 290 300 310 320 330 340 310 320 330 340 350 360 pF1KB3 LQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAIEKPKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAIEKPKAL 350 360 370 380 390 400 370 380 390 400 410 420 pF1KB3 SLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMVAQSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMVAQSQV 410 420 430 440 450 460 430 440 450 460 470 480 pF1KB3 GFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKRSGVKTSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKRSGVKTSGS 470 480 490 500 510 520 490 500 510 520 530 540 pF1KB3 EGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKARLAAEEQQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKARLAAEEQQK 530 540 550 560 570 580 550 560 570 580 590 600 pF1KB3 EMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGEQQQNGDFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGEQQQNGDFK 590 600 610 620 630 640 610 620 630 640 650 660 pF1KB3 DGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLRHFKRPAYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLRHFKRPAYA 650 660 670 680 690 700 670 680 690 700 pF1KB3 SSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK ::::::::::::::::::::::::::::::::::::::::: XP_016 SSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK 710 720 730 740 >>NP_001177987 (OMIM: 602987) calcium/calmodulin-depende (769 aa) initn: 4352 init1: 4352 opt: 4352 Z-score: 3063.9 bits: 577.6 E(85289): 6.4e-164 Smith-Waterman score: 4352; 99.9% identity (99.9% similar) in 671 aa overlap (39-709:99-769) 10 20 30 40 50 60 pF1KB3 EEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVDLKKNLEYA ::: :::::::::::::::::::::::::: NP_001 PRPTIVHDPRPPEEILADELPQLDSPEVLVKTSFRLRSLVKQLERGEASVVDLKKNLEYA 70 80 90 100 110 120 70 80 90 100 110 120 pF1KB3 ATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRRSDEKPRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRRSDEKPRFK 130 140 150 160 170 180 130 140 150 160 170 180 pF1KB3 SIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEASGDHALKFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEASGDHALKFI 190 200 210 220 230 240 190 200 210 220 230 240 pF1KB3 FYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKTG 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB3 VANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRL 310 320 330 340 350 360 310 320 330 340 350 360 pF1KB3 LQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAIEKPKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAIEKPKAL 370 380 390 400 410 420 370 380 390 400 410 420 pF1KB3 SLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMVAQSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMVAQSQV 430 440 450 460 470 480 430 440 450 460 470 480 pF1KB3 GFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKRSGVKTSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKRSGVKTSGS 490 500 510 520 530 540 490 500 510 520 530 540 pF1KB3 EGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKARLAAEEQQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKARLAAEEQQK 550 560 570 580 590 600 550 560 570 580 590 600 pF1KB3 EMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGEQQQNGDFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGEQQQNGDFK 610 620 630 640 650 660 610 620 630 640 650 660 pF1KB3 DGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLRHFKRPAYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLRHFKRPAYA 670 680 690 700 710 720 670 680 690 700 pF1KB3 SSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK ::::::::::::::::::::::::::::::::::::::::: NP_001 SSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK 730 740 750 760 >>XP_016867753 (OMIM: 602987) PREDICTED: calcium/calmodu (804 aa) initn: 4352 init1: 4352 opt: 4352 Z-score: 3063.6 bits: 577.6 E(85289): 6.6e-164 Smith-Waterman score: 4352; 99.9% identity (99.9% similar) in 671 aa overlap (39-709:134-804) 10 20 30 40 50 60 pF1KB3 EEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVDLKKNLEYA ::: :::::::::::::::::::::::::: XP_016 PRPTIVHDPRPPEEILADELPQLDSPEVLVKTSFRLRSLVKQLERGEASVVDLKKNLEYA 110 120 130 140 150 160 70 80 90 100 110 120 pF1KB3 ATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRRSDEKPRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRRSDEKPRFK 170 180 190 200 210 220 130 140 150 160 170 180 pF1KB3 SIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEASGDHALKFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEASGDHALKFI 230 240 250 260 270 280 190 200 210 220 230 240 pF1KB3 FYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKTG 290 300 310 320 330 340 250 260 270 280 290 300 pF1KB3 VANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRL 350 360 370 380 390 400 310 320 330 340 350 360 pF1KB3 LQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAIEKPKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAIEKPKAL 410 420 430 440 450 460 370 380 390 400 410 420 pF1KB3 SLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMVAQSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMVAQSQV 470 480 490 500 510 520 430 440 450 460 470 480 pF1KB3 GFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKRSGVKTSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKRSGVKTSGS 530 540 550 560 570 580 490 500 510 520 530 540 pF1KB3 EGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKARLAAEEQQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKARLAAEEQQK 590 600 610 620 630 640 550 560 570 580 590 600 pF1KB3 EMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGEQQQNGDFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGEQQQNGDFK 650 660 670 680 690 700 610 620 630 640 650 660 pF1KB3 DGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLRHFKRPAYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLRHFKRPAYA 710 720 730 740 750 760 670 680 690 700 pF1KB3 SSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK ::::::::::::::::::::::::::::::::::::::::: XP_016 SSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK 770 780 790 800 >>NP_001308985 (OMIM: 602987) calcium/calmodulin-depende (634 aa) initn: 4381 init1: 4078 opt: 4078 Z-score: 2873.2 bits: 542.0 E(85289): 2.7e-153 Smith-Waterman score: 4078; 99.4% identity (99.8% similar) in 634 aa overlap (1-634:1-634) 10 20 30 40 50 60 pF1KB3 MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLR :::::::::::::::::::::::::::::: ... NP_001 QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDDSQE 610 620 630 670 680 690 700 pF1KB3 HFKRPAYASSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK >>NP_005011 (OMIM: 602987) calcium/calmodulin-dependent (634 aa) initn: 4381 init1: 4078 opt: 4078 Z-score: 2873.2 bits: 542.0 E(85289): 2.7e-153 Smith-Waterman score: 4078; 99.4% identity (99.8% similar) in 634 aa overlap (1-634:1-634) 10 20 30 40 50 60 pF1KB3 MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLR :::::::::::::::::::::::::::::: ... NP_005 QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDDSQE 610 620 630 670 680 690 700 pF1KB3 HFKRPAYASSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK >>NP_001177985 (OMIM: 602987) calcium/calmodulin-depende (634 aa) initn: 4381 init1: 4078 opt: 4078 Z-score: 2873.2 bits: 542.0 E(85289): 2.7e-153 Smith-Waterman score: 4078; 99.4% identity (99.8% similar) in 634 aa overlap (1-634:1-634) 10 20 30 40 50 60 pF1KB3 MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLR :::::::::::::::::::::::::::::: ... NP_001 QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDDSQE 610 620 630 670 680 690 700 pF1KB3 HFKRPAYASSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK 709 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:04:30 2016 done: Sat Nov 5 07:04:32 2016 Total Scan time: 12.020 Total Display time: 0.200 Function used was FASTA [36.3.4 Apr, 2011]