FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3316, 739 aa 1>>>pF1KB3316 739 - 739 aa - 739 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.8262+/-0.000789; mu= -2.2042+/- 0.046 mean_var=645.5652+/-147.232, 0's: 0 Z-trim(113.1): 2039 B-trim: 439 in 1/50 Lambda= 0.050478 statistics sampled from 19521 (22221) to 19521 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.261), width: 16 Scan time: 10.690 The best scores are: opt bits E(85289) XP_005274630 (OMIM: 300075,300844,303600) PREDICTE ( 739) 4910 374.8 6.8e-103 NP_004577 (OMIM: 300075,300844,303600) ribosomal p ( 740) 4898 374.0 1.2e-102 XP_011543858 (OMIM: 300075,300844,303600) PREDICTE ( 745) 4888 373.2 2.1e-102 XP_011543857 (OMIM: 300075,300844,303600) PREDICTE ( 746) 4829 368.9 4.1e-101 XP_006724570 (OMIM: 300075,300844,303600) PREDICTE ( 711) 4719 360.9 1e-98 XP_016885208 (OMIM: 300075,300844,303600) PREDICTE ( 711) 4719 360.9 1e-98 XP_016885205 (OMIM: 300075,300844,303600) PREDICTE ( 712) 4707 360.0 1.9e-98 XP_016885204 (OMIM: 300075,300844,303600) PREDICTE ( 712) 4707 360.0 1.9e-98 XP_016885202 (OMIM: 300075,300844,303600) PREDICTE ( 712) 4707 360.0 1.9e-98 XP_016885206 (OMIM: 300075,300844,303600) PREDICTE ( 712) 4707 360.0 1.9e-98 XP_016885203 (OMIM: 300075,300844,303600) PREDICTE ( 712) 4707 360.0 1.9e-98 XP_011543865 (OMIM: 300075,300844,303600) PREDICTE ( 712) 4707 360.0 1.9e-98 XP_011543862 (OMIM: 300075,300844,303600) PREDICTE ( 718) 4685 358.4 5.7e-98 XP_011543859 (OMIM: 300075,300844,303600) PREDICTE ( 718) 4685 358.4 5.7e-98 XP_011543861 (OMIM: 300075,300844,303600) PREDICTE ( 718) 4685 358.4 5.7e-98 XP_011543863 (OMIM: 300075,300844,303600) PREDICTE ( 718) 4685 358.4 5.7e-98 XP_011543860 (OMIM: 300075,300844,303600) PREDICTE ( 718) 4685 358.4 5.7e-98 XP_005274634 (OMIM: 300075,300844,303600) PREDICTE ( 710) 4621 353.8 1.4e-96 XP_016885207 (OMIM: 300075,300844,303600) PREDICTE ( 711) 4609 352.9 2.6e-96 XP_011543864 (OMIM: 300075,300844,303600) PREDICTE ( 717) 4587 351.3 8.1e-96 NP_001006933 (OMIM: 601685) ribosomal protein S6 k ( 741) 4010 309.3 3.7e-83 NP_001305865 (OMIM: 601685) ribosomal protein S6 k ( 758) 3964 306.0 3.8e-82 XP_006715612 (OMIM: 601685) PREDICTED: ribosomal p ( 761) 3956 305.4 5.6e-82 NP_066958 (OMIM: 601685) ribosomal protein S6 kina ( 733) 3952 305.1 6.8e-82 NP_002944 (OMIM: 601684) ribosomal protein S6 kina ( 735) 3948 304.8 8.3e-82 NP_001317370 (OMIM: 601684) ribosomal protein S6 k ( 719) 3884 300.1 2.1e-80 NP_001006666 (OMIM: 601684) ribosomal protein S6 k ( 744) 3874 299.4 3.5e-80 NP_055311 (OMIM: 300303) ribosomal protein S6 kina ( 745) 3857 298.2 8.3e-80 XP_011529219 (OMIM: 300303) PREDICTED: ribosomal p ( 745) 3829 296.1 3.4e-79 NP_001317441 (OMIM: 300303) ribosomal protein S6 k ( 745) 3829 296.1 3.4e-79 XP_016884912 (OMIM: 300303) PREDICTED: ribosomal p ( 762) 3829 296.1 3.4e-79 XP_016884913 (OMIM: 300303) PREDICTED: ribosomal p ( 762) 3829 296.1 3.4e-79 XP_016884914 (OMIM: 300303) PREDICTED: ribosomal p ( 762) 3829 296.1 3.4e-79 NP_001305867 (OMIM: 601685) ribosomal protein S6 k ( 644) 3659 283.6 1.7e-75 NP_001305866 (OMIM: 601685) ribosomal protein S6 k ( 635) 3549 275.6 4.3e-73 XP_011529221 (OMIM: 300303) PREDICTED: ribosomal p ( 642) 3493 271.5 7.3e-72 XP_011529222 (OMIM: 300303) PREDICTED: ribosomal p ( 624) 3390 264.0 1.3e-69 XP_016884915 (OMIM: 300303) PREDICTED: ribosomal p ( 506) 2656 210.4 1.5e-53 NP_001309165 (OMIM: 603607) ribosomal protein S6 k ( 774) 1409 119.9 3.9e-26 NP_001258972 (OMIM: 608938) ribosomal protein S6 k ( 451) 1266 109.1 4.1e-23 NP_001258989 (OMIM: 608938) ribosomal protein S6 k ( 502) 1266 109.2 4.3e-23 NP_003152 (OMIM: 608938) ribosomal protein S6 kina ( 525) 1266 109.2 4.4e-23 NP_001258973 (OMIM: 608938) ribosomal protein S6 k ( 472) 1251 108.0 8.9e-23 NP_003943 (OMIM: 608939) ribosomal protein S6 kina ( 482) 1227 106.3 3e-22 XP_011523403 (OMIM: 608938) PREDICTED: ribosomal p ( 489) 1167 102.0 6.3e-21 XP_011523404 (OMIM: 608938) PREDICTED: ribosomal p ( 391) 1162 101.4 7.2e-21 XP_016880418 (OMIM: 608938) PREDICTED: ribosomal p ( 436) 1152 100.8 1.3e-20 NP_001287731 (OMIM: 603606) ribosomal protein S6 k ( 765) 1112 98.3 1.3e-19 NP_001006945 (OMIM: 603606) ribosomal protein S6 k ( 766) 1112 98.3 1.3e-19 NP_003933 (OMIM: 603606) ribosomal protein S6 kina ( 772) 1112 98.3 1.3e-19 >>XP_005274630 (OMIM: 300075,300844,303600) PREDICTED: r (739 aa) initn: 4910 init1: 4910 opt: 4910 Z-score: 1968.3 bits: 374.8 E(85289): 6.8e-103 Smith-Waterman score: 4910; 100.0% identity (100.0% similar) in 739 aa overlap (1-739:1-739) 10 20 30 40 50 60 pF1KB3 MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQLHRNSIQFTDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQLHRNSIQFTDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 VYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 PSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 WSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 VDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEPV 670 680 690 700 710 720 730 pF1KB3 GRSTLAQRRGIKKITSTAL ::::::::::::::::::: XP_005 GRSTLAQRRGIKKITSTAL 730 >>NP_004577 (OMIM: 300075,300844,303600) ribosomal prote (740 aa) initn: 2717 init1: 2717 opt: 4898 Z-score: 1963.5 bits: 374.0 E(85289): 1.2e-102 Smith-Waterman score: 4898; 99.9% identity (99.9% similar) in 740 aa overlap (1-739:1-740) 10 20 30 40 50 60 pF1KB3 MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQ-LHRNSIQFTD ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: NP_004 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQQLHRNSIQFTD 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 GYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLK 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB3 IWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKML 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB3 HVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEP 670 680 690 700 710 720 720 730 pF1KB3 VGRSTLAQRRGIKKITSTAL :::::::::::::::::::: NP_004 VGRSTLAQRRGIKKITSTAL 730 740 >>XP_011543858 (OMIM: 300075,300844,303600) PREDICTED: r (745 aa) initn: 2875 init1: 2875 opt: 4888 Z-score: 1959.6 bits: 373.2 E(85289): 2.1e-102 Smith-Waterman score: 4888; 99.2% identity (99.2% similar) in 745 aa overlap (1-739:1-745) 10 20 30 40 50 60 pF1KB3 MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 MLFKRNPANRL------GAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDT ::::::::::: ::::::::::::::::::::::::::::::::::::::::::: XP_011 MLFKRNPANRLVNPFLIGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDT 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 FYFDPEFTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQLHRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FYFDPEFTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQLHRNS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 IQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPN 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGV 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 VHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGY 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB3 DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDL 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB3 VSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQS 670 680 690 700 710 720 720 730 pF1KB3 PVLEPVGRSTLAQRRGIKKITSTAL ::::::::::::::::::::::::: XP_011 PVLEPVGRSTLAQRRGIKKITSTAL 730 740 >>XP_011543857 (OMIM: 300075,300844,303600) PREDICTED: r (746 aa) initn: 4177 init1: 2154 opt: 4829 Z-score: 1936.4 bits: 368.9 E(85289): 4.1e-101 Smith-Waterman score: 4829; 99.1% identity (99.1% similar) in 737 aa overlap (1-730:1-737) 10 20 30 40 50 60 pF1KB3 MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 MLFKRNPANRL------GAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDT ::::::::::: ::::::::::::::::::::::::::::::::::::::::::: XP_011 MLFKRNPANRLVNPFLIGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDT 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 FYFDPEFTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQ-LHRN ::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::: XP_011 FYFDPEFTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQQLHRN 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 SIQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SIQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 VVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQG 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB3 YDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKD 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB3 LVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQ 670 680 690 700 710 720 720 730 pF1KB3 SPVLEPVGRSTLAQRRGIKKITSTAL ::::::::::::::::: XP_011 SPVLEPVGRSTLAQRRGCLHFAGLPK 730 740 >>XP_006724570 (OMIM: 300075,300844,303600) PREDICTED: r (711 aa) initn: 4719 init1: 4719 opt: 4719 Z-score: 1893.2 bits: 360.9 E(85289): 1e-98 Smith-Waterman score: 4719; 100.0% identity (100.0% similar) in 711 aa overlap (29-739:1-711) 10 20 30 40 50 60 pF1KB3 MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH :::::::::::::::::::::::::::::::: XP_006 MDEPMGEEEINPQTEEVSIKEIAITHHVKEGH 10 20 30 70 80 90 100 110 120 pF1KB3 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB3 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB3 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB3 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB3 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB3 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQLHRNSIQFTDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQLHRNSIQFTDG 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB3 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKD 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB3 VYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLK 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB3 PSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDI 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB3 WSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLH 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB3 VDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEPV 640 650 660 670 680 690 730 pF1KB3 GRSTLAQRRGIKKITSTAL ::::::::::::::::::: XP_006 GRSTLAQRRGIKKITSTAL 700 710 >>XP_016885208 (OMIM: 300075,300844,303600) PREDICTED: r (711 aa) initn: 4719 init1: 4719 opt: 4719 Z-score: 1893.2 bits: 360.9 E(85289): 1e-98 Smith-Waterman score: 4719; 100.0% identity (100.0% similar) in 711 aa overlap (29-739:1-711) 10 20 30 40 50 60 pF1KB3 MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH :::::::::::::::::::::::::::::::: XP_016 MDEPMGEEEINPQTEEVSIKEIAITHHVKEGH 10 20 30 70 80 90 100 110 120 pF1KB3 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB3 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB3 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB3 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB3 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB3 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQLHRNSIQFTDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQLHRNSIQFTDG 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB3 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKD 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB3 VYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLK 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB3 PSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDI 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB3 WSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLH 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB3 VDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEPV 640 650 660 670 680 690 730 pF1KB3 GRSTLAQRRGIKKITSTAL ::::::::::::::::::: XP_016 GRSTLAQRRGIKKITSTAL 700 710 >>XP_016885205 (OMIM: 300075,300844,303600) PREDICTED: r (712 aa) initn: 2526 init1: 2526 opt: 4707 Z-score: 1888.5 bits: 360.0 E(85289): 1.9e-98 Smith-Waterman score: 4707; 99.9% identity (99.9% similar) in 712 aa overlap (29-739:1-712) 10 20 30 40 50 60 pF1KB3 MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH :::::::::::::::::::::::::::::::: XP_016 MDEPMGEEEINPQTEEVSIKEIAITHHVKEGH 10 20 30 70 80 90 100 110 120 pF1KB3 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB3 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB3 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB3 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB3 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 280 290 300 310 320 330 370 380 390 400 410 pF1KB3 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQ-LHRNSIQFTD ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_016 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQQLHRNSIQFTD 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB3 GYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLK 400 410 420 430 440 450 480 490 500 510 520 530 pF1KB3 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL 460 470 480 490 500 510 540 550 560 570 580 590 pF1KB3 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD 520 530 540 550 560 570 600 610 620 630 640 650 pF1KB3 IWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKML 580 590 600 610 620 630 660 670 680 690 700 710 pF1KB3 HVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEP 640 650 660 670 680 690 720 730 pF1KB3 VGRSTLAQRRGIKKITSTAL :::::::::::::::::::: XP_016 VGRSTLAQRRGIKKITSTAL 700 710 >>XP_016885204 (OMIM: 300075,300844,303600) PREDICTED: r (712 aa) initn: 2526 init1: 2526 opt: 4707 Z-score: 1888.5 bits: 360.0 E(85289): 1.9e-98 Smith-Waterman score: 4707; 99.9% identity (99.9% similar) in 712 aa overlap (29-739:1-712) 10 20 30 40 50 60 pF1KB3 MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH :::::::::::::::::::::::::::::::: XP_016 MDEPMGEEEINPQTEEVSIKEIAITHHVKEGH 10 20 30 70 80 90 100 110 120 pF1KB3 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB3 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB3 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB3 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB3 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 280 290 300 310 320 330 370 380 390 400 410 pF1KB3 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQ-LHRNSIQFTD ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_016 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQQLHRNSIQFTD 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB3 GYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLK 400 410 420 430 440 450 480 490 500 510 520 530 pF1KB3 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL 460 470 480 490 500 510 540 550 560 570 580 590 pF1KB3 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD 520 530 540 550 560 570 600 610 620 630 640 650 pF1KB3 IWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKML 580 590 600 610 620 630 660 670 680 690 700 710 pF1KB3 HVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEP 640 650 660 670 680 690 720 730 pF1KB3 VGRSTLAQRRGIKKITSTAL :::::::::::::::::::: XP_016 VGRSTLAQRRGIKKITSTAL 700 710 >>XP_016885202 (OMIM: 300075,300844,303600) PREDICTED: r (712 aa) initn: 2526 init1: 2526 opt: 4707 Z-score: 1888.5 bits: 360.0 E(85289): 1.9e-98 Smith-Waterman score: 4707; 99.9% identity (99.9% similar) in 712 aa overlap (29-739:1-712) 10 20 30 40 50 60 pF1KB3 MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH :::::::::::::::::::::::::::::::: XP_016 MDEPMGEEEINPQTEEVSIKEIAITHHVKEGH 10 20 30 70 80 90 100 110 120 pF1KB3 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB3 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB3 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB3 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB3 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 280 290 300 310 320 330 370 380 390 400 410 pF1KB3 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQ-LHRNSIQFTD ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_016 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQQLHRNSIQFTD 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB3 GYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLK 400 410 420 430 440 450 480 490 500 510 520 530 pF1KB3 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL 460 470 480 490 500 510 540 550 560 570 580 590 pF1KB3 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD 520 530 540 550 560 570 600 610 620 630 640 650 pF1KB3 IWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKML 580 590 600 610 620 630 660 670 680 690 700 710 pF1KB3 HVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEP 640 650 660 670 680 690 720 730 pF1KB3 VGRSTLAQRRGIKKITSTAL :::::::::::::::::::: XP_016 VGRSTLAQRRGIKKITSTAL 700 710 >>XP_016885206 (OMIM: 300075,300844,303600) PREDICTED: r (712 aa) initn: 2526 init1: 2526 opt: 4707 Z-score: 1888.5 bits: 360.0 E(85289): 1.9e-98 Smith-Waterman score: 4707; 99.9% identity (99.9% similar) in 712 aa overlap (29-739:1-712) 10 20 30 40 50 60 pF1KB3 MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH :::::::::::::::::::::::::::::::: XP_016 MDEPMGEEEINPQTEEVSIKEIAITHHVKEGH 10 20 30 70 80 90 100 110 120 pF1KB3 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERD 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB3 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB3 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVV 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB3 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLR 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB3 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 280 290 300 310 320 330 370 380 390 400 410 pF1KB3 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQ-LHRNSIQFTD ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_016 FTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQQLHRNSIQFTD 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB3 GYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLK 400 410 420 430 440 450 480 490 500 510 520 530 pF1KB3 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDL 460 470 480 490 500 510 540 550 560 570 580 590 pF1KB3 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD 520 530 540 550 560 570 600 610 620 630 640 650 pF1KB3 IWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKML 580 590 600 610 620 630 660 670 680 690 700 710 pF1KB3 HVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRNQSPVLEP 640 650 660 670 680 690 720 730 pF1KB3 VGRSTLAQRRGIKKITSTAL :::::::::::::::::::: XP_016 VGRSTLAQRRGIKKITSTAL 700 710 739 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:49:11 2016 done: Thu Nov 3 12:49:13 2016 Total Scan time: 10.690 Total Display time: 0.210 Function used was FASTA [36.3.4 Apr, 2011]