Result of FASTA (omim) for
pF1KB3321
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3321, 923 aa
1>>>pF1KB3321 923 - 923 aa - 923 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6794+/-0.000366; mu= 19.2347+/- 0.023
mean_var=80.4035+/-16.225, 0's: 0 Z-trim(114.6): 240 B-trim: 33 in 1/52
Lambda= 0.143033
statistics sampled from 24299 (24564) to 24299 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.288), width: 16
Scan time: 14.180
The best scores are: opt bits E(85289)
NP_001092001 (OMIM: 606057) rap guanine nucleotide ( 923) 6240 1298.0 0
NP_006096 (OMIM: 606057) rap guanine nucleotide ex ( 881) 5941 1236.3 0
NP_001092002 (OMIM: 606057) rap guanine nucleotide ( 881) 5941 1236.3 0
XP_011536057 (OMIM: 606057) PREDICTED: rap guanine ( 896) 5075 1057.6 0
XP_011536054 (OMIM: 606057) PREDICTED: rap guanine ( 938) 5075 1057.6 0
XP_011536060 (OMIM: 606057) PREDICTED: rap guanine ( 779) 5010 1044.1 0
XP_005268628 (OMIM: 606057) PREDICTED: rap guanine ( 495) 3350 701.5 2.7e-201
NP_001269828 (OMIM: 606058) rap guanine nucleotide ( 858) 2683 564.0 1.1e-159
NP_001093867 (OMIM: 606058) rap guanine nucleotide ( 867) 2683 564.0 1.1e-159
XP_011508807 (OMIM: 606058) PREDICTED: rap guanine ( 881) 2683 564.0 1.2e-159
NP_008954 (OMIM: 606058) rap guanine nucleotide ex (1011) 2683 564.0 1.3e-159
XP_005246303 (OMIM: 606058) PREDICTED: rap guanine ( 993) 2673 562.0 5.3e-159
NP_001269829 (OMIM: 606058) rap guanine nucleotide ( 840) 2670 561.3 7.1e-159
XP_006712268 (OMIM: 606058) PREDICTED: rap guanine ( 840) 2670 561.3 7.1e-159
XP_016858686 (OMIM: 606058) PREDICTED: rap guanine ( 849) 2670 561.3 7.2e-159
XP_016858685 (OMIM: 606058) PREDICTED: rap guanine ( 960) 2619 550.8 1.2e-155
NP_001269830 (OMIM: 606058) rap guanine nucleotide ( 791) 2606 548.1 6.4e-155
XP_016874177 (OMIM: 606057) PREDICTED: rap guanine ( 510) 1635 347.6 9.3e-95
NP_036426 (OMIM: 609527) rap guanine nucleotide ex ( 730) 1225 263.1 3.7e-69
XP_005249973 (OMIM: 609527) PREDICTED: rap guanine ( 730) 1225 263.1 3.7e-69
XP_016868326 (OMIM: 609527) PREDICTED: rap guanine ( 758) 1225 263.1 3.8e-69
XP_005249971 (OMIM: 609527) PREDICTED: rap guanine ( 883) 1225 263.1 4.3e-69
XP_011513954 (OMIM: 609527) PREDICTED: rap guanine ( 554) 1184 254.5 1e-66
NP_055062 (OMIM: 609530) rap guanine nucleotide ex (1499) 532 120.3 7.4e-26
XP_016864348 (OMIM: 609530) PREDICTED: rap guanine (1524) 532 120.3 7.5e-26
XP_011530729 (OMIM: 609530) PREDICTED: rap guanine (1540) 532 120.3 7.5e-26
XP_016864346 (OMIM: 609530) PREDICTED: rap guanine (1544) 532 120.3 7.5e-26
XP_016864347 (OMIM: 609530) PREDICTED: rap guanine (1544) 532 120.3 7.5e-26
XP_011530728 (OMIM: 609530) PREDICTED: rap guanine (1585) 532 120.3 7.7e-26
XP_006714485 (OMIM: 609530) PREDICTED: rap guanine (1585) 532 120.3 7.7e-26
XP_011530727 (OMIM: 609530) PREDICTED: rap guanine (1589) 532 120.3 7.7e-26
XP_016864345 (OMIM: 609530) PREDICTED: rap guanine (1652) 532 120.3 8e-26
XP_005263418 (OMIM: 609530) PREDICTED: rap guanine (1654) 532 120.3 8e-26
XP_005263417 (OMIM: 609530) PREDICTED: rap guanine (1660) 532 120.3 8e-26
XP_006714484 (OMIM: 609530) PREDICTED: rap guanine (1685) 532 120.3 8.1e-26
XP_005263416 (OMIM: 609530) PREDICTED: rap guanine (1693) 532 120.3 8.1e-26
XP_006714483 (OMIM: 609530) PREDICTED: rap guanine (1695) 532 120.3 8.1e-26
XP_005263415 (OMIM: 609530) PREDICTED: rap guanine (1701) 532 120.3 8.2e-26
NP_001157861 (OMIM: 610499) rap guanine nucleotide (1391) 505 114.7 3.3e-24
NP_057424 (OMIM: 610499) rap guanine nucleotide ex (1601) 505 114.7 3.7e-24
NP_001157859 (OMIM: 610499) rap guanine nucleotide (1509) 504 114.5 4.1e-24
NP_001157860 (OMIM: 610499) rap guanine nucleotide (1504) 503 114.3 4.7e-24
NP_001157858 (OMIM: 610499) rap guanine nucleotide (1609) 503 114.3 4.9e-24
NP_001157862 (OMIM: 610499) rap guanine nucleotide ( 827) 384 89.6 7.1e-17
NP_005303 (OMIM: 600303) rap guanine nucleotide ex (1077) 352 83.0 8.5e-15
NP_001291204 (OMIM: 600303) rap guanine nucleotide (1094) 352 83.0 8.7e-15
NP_941372 (OMIM: 600303) rap guanine nucleotide ex (1095) 352 83.0 8.7e-15
XP_006717137 (OMIM: 600303) PREDICTED: rap guanine (1100) 352 83.0 8.7e-15
XP_011516881 (OMIM: 600303) PREDICTED: rap guanine (1108) 352 83.0 8.7e-15
XP_011516880 (OMIM: 600303) PREDICTED: rap guanine (1139) 352 83.1 8.9e-15
>>NP_001092001 (OMIM: 606057) rap guanine nucleotide exc (923 aa)
initn: 6240 init1: 6240 opt: 6240 Z-score: 6954.0 bits: 1298.0 E(85289): 0
Smith-Waterman score: 6240; 100.0% identity (100.0% similar) in 923 aa overlap (1-923:1-923)
10 20 30 40 50 60
pF1KB3 MKVGWPGESCWQVGLAVEDSPALGAPRVGALPDVVPEGTLLNMVLRRMHRPRSCSYQLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKVGWPGESCWQVGLAVEDSPALGAPRVGALPDVVPEGTLLNMVLRRMHRPRSCSYQLLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 EHQRPSCIQGLRWTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHQRPSCIQGLRWTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 YHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDEGALCHVKHDWAFQDRDAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDEGALCHVKHDWAFQDRDAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 FYRFPGPEPEPVGTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYRFPGPEPEPVGTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLEEHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLEEHG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 KVVLVLERASQGAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMGPDSSAHDPTETFLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVVLVLERASQGAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMGPDSSAHDPTETFLSD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 FLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERSTYVCNKRQQILRLVSQWVALYGSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERSTYVCNKRQQILRLVSQWVALYGSML
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 HTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRRCHRLENGCGNASPQMKARNLPVWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRRCHRLENGCGNASPQMKARNLPVWL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 PNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPVTASVREVMAALAQEDGWTKGQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPVTASVREVMAALAQEDGWTKGQV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEVHELIPHPDQLGPTVGSAEGLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEVHELIPHPDQLGPTVGSAEGLDL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVAT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 ELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 RKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLVENLINFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLVENLINFE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 KMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPASTWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPASTWA
850 860 870 880 890 900
910 920
pF1KB3 YVQQLKVIDNQRELSRLSRELEP
:::::::::::::::::::::::
NP_001 YVQQLKVIDNQRELSRLSRELEP
910 920
>>NP_006096 (OMIM: 606057) rap guanine nucleotide exchan (881 aa)
initn: 5941 init1: 5941 opt: 5941 Z-score: 6620.9 bits: 1236.3 E(85289): 0
Smith-Waterman score: 5941; 100.0% identity (100.0% similar) in 881 aa overlap (43-923:1-881)
20 30 40 50 60 70
pF1KB3 VGLAVEDSPALGAPRVGALPDVVPEGTLLNMVLRRMHRPRSCSYQLLLEHQRPSCIQGLR
::::::::::::::::::::::::::::::
NP_006 MVLRRMHRPRSCSYQLLLEHQRPSCIQGLR
10 20 30
80 90 100 110 120 130
pF1KB3 WTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRKYHLRLYRQCCSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 WTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRKYHLRLYRQCCSG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB3 RELVDGILALGLGVHSRSQVVGICQVLLDEGALCHVKHDWAFQDRDAQFYRFPGPEPEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RELVDGILALGLGVHSRSQVVGICQVLLDEGALCHVKHDWAFQDRDAQFYRFPGPEPEPV
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB3 GTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNS
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB3 VKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQ
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB3 LALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQG
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB3 AGPSRPPTPGRNRYTVMSGTPEKILELLLEAMGPDSSAHDPTETFLSDFLLTHRVFMPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AGPSRPPTPGRNRYTVMSGTPEKILELLLEAMGPDSSAHDPTETFLSDFLLTHRVFMPSA
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB3 QLCAALLHHFHVEPAGGSEQERSTYVCNKRQQILRLVSQWVALYGSMLHTDPVATSFLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QLCAALLHHFHVEPAGGSEQERSTYVCNKRQQILRLVSQWVALYGSMLHTDPVATSFLQK
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB3 LSDLVGRDTRLSNLLREQWPERRRCHRLENGCGNASPQMKARNLPVWLPNQDEPLPGSSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LSDLVGRDTRLSNLLREQWPERRRCHRLENGCGNASPQMKARNLPVWLPNQDEPLPGSSC
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB3 AIQVGDKVPYDICRPDHSVLTLQLPVTASVREVMAALAQEDGWTKGQVLVKVNSAGDAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AIQVGDKVPYDICRPDHSVLTLQLPVTASVREVMAALAQEDGWTKGQVLVKVNSAGDAIG
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB3 LQPDARGVATSLGLNERLFVVNPQEVHELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LQPDARGVATSLGLNERLFVVNPQEVHELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLTD
580 590 600 610 620 630
680 690 700 710 720 730
pF1KB3 HDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRA
640 650 660 670 680 690
740 750 760 770 780 790
pF1KB3 QLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLD
700 710 720 730 740 750
800 810 820 830 840 850
pF1KB3 PSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLVENLINFEKMRMMARAARML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLVENLINFEKMRMMARAARML
760 770 780 790 800 810
860 870 880 890 900 910
pF1KB3 HHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPASTWAYVQQLKVIDNQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPASTWAYVQQLKVIDNQR
820 830 840 850 860 870
920
pF1KB3 ELSRLSRELEP
:::::::::::
NP_006 ELSRLSRELEP
880
>>NP_001092002 (OMIM: 606057) rap guanine nucleotide exc (881 aa)
initn: 5941 init1: 5941 opt: 5941 Z-score: 6620.9 bits: 1236.3 E(85289): 0
Smith-Waterman score: 5941; 100.0% identity (100.0% similar) in 881 aa overlap (43-923:1-881)
20 30 40 50 60 70
pF1KB3 VGLAVEDSPALGAPRVGALPDVVPEGTLLNMVLRRMHRPRSCSYQLLLEHQRPSCIQGLR
::::::::::::::::::::::::::::::
NP_001 MVLRRMHRPRSCSYQLLLEHQRPSCIQGLR
10 20 30
80 90 100 110 120 130
pF1KB3 WTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRKYHLRLYRQCCSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRKYHLRLYRQCCSG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB3 RELVDGILALGLGVHSRSQVVGICQVLLDEGALCHVKHDWAFQDRDAQFYRFPGPEPEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RELVDGILALGLGVHSRSQVVGICQVLLDEGALCHVKHDWAFQDRDAQFYRFPGPEPEPV
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB3 GTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNS
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB3 VKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQ
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB3 LALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQG
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB3 AGPSRPPTPGRNRYTVMSGTPEKILELLLEAMGPDSSAHDPTETFLSDFLLTHRVFMPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGPSRPPTPGRNRYTVMSGTPEKILELLLEAMGPDSSAHDPTETFLSDFLLTHRVFMPSA
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB3 QLCAALLHHFHVEPAGGSEQERSTYVCNKRQQILRLVSQWVALYGSMLHTDPVATSFLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLCAALLHHFHVEPAGGSEQERSTYVCNKRQQILRLVSQWVALYGSMLHTDPVATSFLQK
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB3 LSDLVGRDTRLSNLLREQWPERRRCHRLENGCGNASPQMKARNLPVWLPNQDEPLPGSSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSDLVGRDTRLSNLLREQWPERRRCHRLENGCGNASPQMKARNLPVWLPNQDEPLPGSSC
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB3 AIQVGDKVPYDICRPDHSVLTLQLPVTASVREVMAALAQEDGWTKGQVLVKVNSAGDAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIQVGDKVPYDICRPDHSVLTLQLPVTASVREVMAALAQEDGWTKGQVLVKVNSAGDAIG
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB3 LQPDARGVATSLGLNERLFVVNPQEVHELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQPDARGVATSLGLNERLFVVNPQEVHELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLTD
580 590 600 610 620 630
680 690 700 710 720 730
pF1KB3 HDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRA
640 650 660 670 680 690
740 750 760 770 780 790
pF1KB3 QLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLD
700 710 720 730 740 750
800 810 820 830 840 850
pF1KB3 PSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLVENLINFEKMRMMARAARML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLVENLINFEKMRMMARAARML
760 770 780 790 800 810
860 870 880 890 900 910
pF1KB3 HHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPASTWAYVQQLKVIDNQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPASTWAYVQQLKVIDNQR
820 830 840 850 860 870
920
pF1KB3 ELSRLSRELEP
:::::::::::
NP_001 ELSRLSRELEP
880
>>XP_011536057 (OMIM: 606057) PREDICTED: rap guanine nuc (896 aa)
initn: 5916 init1: 5071 opt: 5075 Z-score: 5655.0 bits: 1057.6 E(85289): 0
Smith-Waterman score: 5890; 98.2% identity (98.2% similar) in 896 aa overlap (43-923:1-896)
20 30 40 50 60 70
pF1KB3 VGLAVEDSPALGAPRVGALPDVVPEGTLLNMVLRRMHRPRSCSYQLLLEHQRPSCIQGLR
::::::::::::::::::::::::::::::
XP_011 MVLRRMHRPRSCSYQLLLEHQRPSCIQGLR
10 20 30
80 90 100 110 120 130
pF1KB3 WTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRKYHLRLYRQCCSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRKYHLRLYRQCCSG
40 50 60 70 80 90
140 150 160 170
pF1KB3 RELVDGILALGLGVHSRSQVVGICQVLLDEGALCH---------------VKHDWAFQDR
::::::::::::::::::::::::::::::::::: ::::::::::
XP_011 RELVDGILALGLGVHSRSQVVGICQVLLDEGALCHASISSPPPRLGLCPPVKHDWAFQDR
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB3 DAQFYRFPGPEPEPVGTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIF
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAQFYRFPGPEPEPVRTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIF
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB3 EELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHG
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB3 KGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLE
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB3 EHGKVVLVLERASQGAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMGPDSSAHDPTETF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHGKVVLVLERASQGAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMGPDSSAHDPTETF
340 350 360 370 380 390
420 430 440 450 460 470
pF1KB3 LSDFLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERSTYVCNKRQQILRLVSQWVALYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSDFLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERSTYVCNKRQQILRLVSQWVALYG
400 410 420 430 440 450
480 490 500 510 520 530
pF1KB3 SMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRRCHRLENGCGNASPQMKARNLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRRCHRLENGCGNASPQMKARNLP
460 470 480 490 500 510
540 550 560 570 580 590
pF1KB3 VWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPVTASVREVMAALAQEDGWTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPVTASVREVMAALAQEDGWTK
520 530 540 550 560 570
600 610 620 630 640 650
pF1KB3 GQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEVHELIPHPDQLGPTVGSAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEVHELIPHPDQLGPTVGSAEG
580 590 600 610 620 630
660 670 680 690 700 710
pF1KB3 LDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYW
640 650 660 670 680 690
720 730 740 750 760 770
pF1KB3 VATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLP
700 710 720 730 740 750
780 790 800 810 820 830
pF1KB3 HKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLVENLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLVENLI
760 770 780 790 800 810
840 850 860 870 880 890
pF1KB3 NFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPAS
820 830 840 850 860 870
900 910 920
pF1KB3 TWAYVQQLKVIDNQRELSRLSRELEP
::::::::::::::::::::::::::
XP_011 TWAYVQQLKVIDNQRELSRLSRELEP
880 890
>>XP_011536054 (OMIM: 606057) PREDICTED: rap guanine nuc (938 aa)
initn: 6215 init1: 5071 opt: 5075 Z-score: 5654.7 bits: 1057.6 E(85289): 0
Smith-Waterman score: 6189; 98.3% identity (98.3% similar) in 938 aa overlap (1-923:1-938)
10 20 30 40 50 60
pF1KB3 MKVGWPGESCWQVGLAVEDSPALGAPRVGALPDVVPEGTLLNMVLRRMHRPRSCSYQLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKVGWPGESCWQVGLAVEDSPALGAPRVGALPDVVPEGTLLNMVLRRMHRPRSCSYQLLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 EHQRPSCIQGLRWTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHQRPSCIQGLRWTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRK
70 80 90 100 110 120
130 140 150 160
pF1KB3 YHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDEGALCH-------------
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDEGALCHASISSPPPRLGLC
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB3 --VKHDWAFQDRDAQFYRFPGPEPEPVGTHEMEEELAEAVALLSQRGPDALLTVALRKPP
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 PPVKHDWAFQDRDAQFYRFPGPEPEPVRTHEMEEELAEAVALLSQRGPDALLTVALRKPP
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB3 GQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB3 IWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFNRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFNRI
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB3 IKDVEAKTMRLEEHGKVVLVLERASQGAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKDVEAKTMRLEEHGKVVLVLERASQGAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMG
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB3 PDSSAHDPTETFLSDFLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERSTYVCNKRQQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDSSAHDPTETFLSDFLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERSTYVCNKRQQI
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB3 LRLVSQWVALYGSMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRRCHRLENGCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRLVSQWVALYGSMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRRCHRLENGCG
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB3 NASPQMKARNLPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPVTASVREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASPQMKARNLPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPVTASVREV
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB3 MAALAQEDGWTKGQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEVHELIPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAALAQEDGWTKGQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEVHELIPHP
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB3 DQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLRDVTTANLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLRDVTTANLE
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB3 RFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSA
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB3 ISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFI
790 800 810 820 830 840
830 840 850 860 870 880
pF1KB3 HEGNHTLVENLINFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHEDSQVARISTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HEGNHTLVENLINFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHEDSQVARISTC
850 860 870 880 890 900
890 900 910 920
pF1KB3 SEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELEP
::::::::::::::::::::::::::::::::::::::
XP_011 SEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELEP
910 920 930
>>XP_011536060 (OMIM: 606057) PREDICTED: rap guanine nuc (779 aa)
initn: 5007 init1: 5007 opt: 5010 Z-score: 5583.4 bits: 1044.1 E(85289): 0
Smith-Waterman score: 5010; 98.4% identity (99.0% similar) in 762 aa overlap (162-923:18-779)
140 150 160 170 180 190
pF1KB3 GRELVDGILALGLGVHSRSQVVGICQVLLDEGALCHVKHDWAFQDRDAQFYRFPGPEPEP
:.: : . . .::::::::::::::::
XP_011 MGSWPWDLGSIPGAKLWESARCCWMKVPSAMDRDAQFYRFPGPEPEP
10 20 30 40
200 210 220 230 240 250
pF1KB3 VGTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSN
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSN
50 60 70 80 90 100
260 270 280 290 300 310
pF1KB3 SVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFG
110 120 130 140 150 160
320 330 340 350 360 370
pF1KB3 QLALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQ
170 180 190 200 210 220
380 390 400 410 420 430
pF1KB3 GAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMGPDSSAHDPTETFLSDFLLTHRVFMPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMGPDSSAHDPTETFLSDFLLTHRVFMPS
230 240 250 260 270 280
440 450 460 470 480 490
pF1KB3 AQLCAALLHHFHVEPAGGSEQERSTYVCNKRQQILRLVSQWVALYGSMLHTDPVATSFLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQLCAALLHHFHVEPAGGSEQERSTYVCNKRQQILRLVSQWVALYGSMLHTDPVATSFLQ
290 300 310 320 330 340
500 510 520 530 540 550
pF1KB3 KLSDLVGRDTRLSNLLREQWPERRRCHRLENGCGNASPQMKARNLPVWLPNQDEPLPGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLSDLVGRDTRLSNLLREQWPERRRCHRLENGCGNASPQMKARNLPVWLPNQDEPLPGSS
350 360 370 380 390 400
560 570 580 590 600 610
pF1KB3 CAIQVGDKVPYDICRPDHSVLTLQLPVTASVREVMAALAQEDGWTKGQVLVKVNSAGDAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAIQVGDKVPYDICRPDHSVLTLQLPVTASVREVMAALAQEDGWTKGQVLVKVNSAGDAI
410 420 430 440 450 460
620 630 640 650 660 670
pF1KB3 GLQPDARGVATSLGLNERLFVVNPQEVHELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLQPDARGVATSLGLNERLFVVNPQEVHELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLT
470 480 490 500 510 520
680 690 700 710 720 730
pF1KB3 DHDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPR
530 540 550 560 570 580
740 750 760 770 780 790
pF1KB3 AQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLL
590 600 610 620 630 640
800 810 820 830 840 850
pF1KB3 DPSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLVENLINFEKMRMMARAARM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLVENLINFEKMRMMARAARM
650 660 670 680 690 700
860 870 880 890 900 910
pF1KB3 LHHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPASTWAYVQQLKVIDNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPASTWAYVQQLKVIDNQ
710 720 730 740 750 760
920
pF1KB3 RELSRLSRELEP
::::::::::::
XP_011 RELSRLSRELEP
770
>>XP_005268628 (OMIM: 606057) PREDICTED: rap guanine nuc (495 aa)
initn: 3350 init1: 3350 opt: 3350 Z-score: 3735.0 bits: 701.5 E(85289): 2.7e-201
Smith-Waterman score: 3350; 100.0% identity (100.0% similar) in 495 aa overlap (429-923:1-495)
400 410 420 430 440 450
pF1KB3 LLLEAMGPDSSAHDPTETFLSDFLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERSTYV
::::::::::::::::::::::::::::::
XP_005 MPSAQLCAALLHHFHVEPAGGSEQERSTYV
10 20 30
460 470 480 490 500 510
pF1KB3 CNKRQQILRLVSQWVALYGSMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRRCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CNKRQQILRLVSQWVALYGSMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRRCH
40 50 60 70 80 90
520 530 540 550 560 570
pF1KB3 RLENGCGNASPQMKARNLPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLENGCGNASPQMKARNLPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPV
100 110 120 130 140 150
580 590 600 610 620 630
pF1KB3 TASVREVMAALAQEDGWTKGQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TASVREVMAALAQEDGWTKGQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEV
160 170 180 190 200 210
640 650 660 670 680 690
pF1KB3 HELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLRD
220 230 240 250 260 270
700 710 720 730 740 750
pF1KB3 VTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVM
280 290 300 310 320 330
760 770 780 790 800 810
pF1KB3 FGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMPLL
340 350 360 370 380 390
820 830 840 850 860 870
pF1KB3 LKDMTFIHEGNHTLVENLINFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHEDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKDMTFIHEGNHTLVENLINFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHEDSQ
400 410 420 430 440 450
880 890 900 910 920
pF1KB3 VARISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELEP
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 VARISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELEP
460 470 480 490
>>NP_001269828 (OMIM: 606058) rap guanine nucleotide exc (858 aa)
initn: 2380 init1: 846 opt: 2683 Z-score: 2987.6 bits: 564.0 E(85289): 1.1e-159
Smith-Waterman score: 2733; 50.1% identity (76.8% similar) in 857 aa overlap (74-923:27-855)
50 60 70 80 90 100
pF1KB3 VLRRMHRPRSCSYQLLLEHQRPSCIQGLRWTPLTNSEESLDFSESLEQASTERVLRAGRQ
::: . . : .... .. .:..::::.
NP_001 MAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKI
10 20 30 40 50
110 120 130 140 150 160
pF1KB3 LHRHLLATCPNLIRDRKYHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDEG
:. .:. :..::::::::. ::::: : :::: .. ::::.:.::. ::::..:
NP_001 LRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDG
60 70 80 90 100 110
170 180 190 200 210
pF1KB3 ALCHVKHDWAFQDRDAQFYRFPGPEPE--PVGTHEM----EEELAEAVALLSQRGPDALL
.: :: .. :::. :::: : : :. :.: .::: ... :::: :::: .
NP_001 VLNHVDQEHHFQDK-YLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHM
120 130 140 150 160 170
220 230 240 250 260 270
pF1KB3 TVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQG
. ::::::::: ..:..:.::::::::..:::..::::::.::.:: :.:.:::::.::
NP_001 RMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQG
180 190 200 210 220 230
280 290 300 310 320 330
pF1KB3 DKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRV
..::::::: ::::::: .:::.: :::::::::.:::::::::::.:.:::::::::::
NP_001 EEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRV
240 250 260 270 280 290
340 350 360 370 380 390
pF1KB3 DKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQGAGPS-RPPTPGRNRYTVMSGTPEKI
::.:::::..::::.:.::.:: . :::::.. : : . . ...:::::::::::
NP_001 DKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKI
300 310 320 330 340 350
400 410 420 430 440 450
pF1KB3 LELLLEAMGPDSSAHDPTETFLSDFLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERST
:: .::.. ... .. :.. :.::.. : ::::..::: ::. :.:..:. :.:::.
NP_001 LEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMD
360 370 380 390 400 410
460 470 480 490 500 510
pF1KB3 YVCNKRQQILRLVSQWVALYGSMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRR
:. :......::: ::.:.::..:. : :. .::... :. :.:. :.:: :: ..
NP_001 YALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEK
420 430 440 450 460 470
520 530 540 550 560 570
pF1KB3 CHRLENGCGNASPQMKARNLPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQL
. . . .:: : . : . . :: . :. .:.: . . ::. :...
NP_001 IVK-QISEDAKAPQKKHKVLLQQFNTGDERAQKRQ-PIRGSDEVLFKVYCMDHTYTTIRV
480 490 500 510 520 530
580 590 600 610 620 630
pF1KB3 PVTASVREVMAALAQEDGWTKGQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQ
::..::.::..:.:.. : .: ..::..:.:. . :.:. .: :.: .: :::. .
NP_001 PVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPRE
540 550 560 570 580 590
640 650 660 670 680 690
pF1KB3 EVHELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHL
. : : :.: :::::.. ..:.:.:::: :.: .:: ::: .:..:::....: ...
NP_001 QFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNF
600 610 620 630 640 650
700 710 720 730 740 750
pF1KB3 RDVTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFA
. :::::. :.:::::.:.::.::.::: . :.:::.::::.::: :: ::::::::
NP_001 KK-TTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFA
660 670 680 690 700 710
760 770 780 790 800 810
pF1KB3 VMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMP
...:::: :.:::: :::.:: : .:.:. .: :.::: :::.:::..::: ::.:::::
NP_001 IVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMP
720 730 740 750 760 770
820 830 840 850 860 870
pF1KB3 LLLKDMTFIHEGNHTLVENLINFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHED
::.::::: ::::.:...::.:::::::.: .:: ... ::. :..: ..... :.:
NP_001 LLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQ---PFNPDAAQANKNHQD
780 790 800 810 820
880 890 900 910 920
pF1KB3 SQVARISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELEP
.:: ::.::.:::::: ::..:..:::
NP_001 ---------------VRS------YVRQLNVIDNQRTLSQMSHRLEPRRP
830 840 850
>>NP_001093867 (OMIM: 606058) rap guanine nucleotide exc (867 aa)
initn: 2380 init1: 846 opt: 2683 Z-score: 2987.6 bits: 564.0 E(85289): 1.1e-159
Smith-Waterman score: 2733; 50.1% identity (76.8% similar) in 857 aa overlap (74-923:36-864)
50 60 70 80 90 100
pF1KB3 VLRRMHRPRSCSYQLLLEHQRPSCIQGLRWTPLTNSEESLDFSESLEQASTERVLRAGRQ
::: . . : .... .. .:..::::.
NP_001 YRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKI
10 20 30 40 50 60
110 120 130 140 150 160
pF1KB3 LHRHLLATCPNLIRDRKYHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDEG
:. .:. :..::::::::. ::::: : :::: .. ::::.:.::. ::::..:
NP_001 LRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDG
70 80 90 100 110 120
170 180 190 200 210
pF1KB3 ALCHVKHDWAFQDRDAQFYRFPGPEPE--PVGTHEM----EEELAEAVALLSQRGPDALL
.: :: .. :::. :::: : : :. :.: .::: ... :::: :::: .
NP_001 VLNHVDQEHHFQDK-YLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHM
130 140 150 160 170 180
220 230 240 250 260 270
pF1KB3 TVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQG
. ::::::::: ..:..:.::::::::..:::..::::::.::.:: :.:.:::::.::
NP_001 RMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQG
190 200 210 220 230 240
280 290 300 310 320 330
pF1KB3 DKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRV
..::::::: ::::::: .:::.: :::::::::.:::::::::::.:.:::::::::::
NP_001 EEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRV
250 260 270 280 290 300
340 350 360 370 380 390
pF1KB3 DKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQGAGPS-RPPTPGRNRYTVMSGTPEKI
::.:::::..::::.:.::.:: . :::::.. : : . . ...:::::::::::
NP_001 DKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKI
310 320 330 340 350 360
400 410 420 430 440 450
pF1KB3 LELLLEAMGPDSSAHDPTETFLSDFLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERST
:: .::.. ... .. :.. :.::.. : ::::..::: ::. :.:..:. :.:::.
NP_001 LEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMD
370 380 390 400 410 420
460 470 480 490 500 510
pF1KB3 YVCNKRQQILRLVSQWVALYGSMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRR
:. :......::: ::.:.::..:. : :. .::... :. :.:. :.:: :: ..
NP_001 YALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEK
430 440 450 460 470 480
520 530 540 550 560 570
pF1KB3 CHRLENGCGNASPQMKARNLPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQL
. . . .:: : . : . . :: . :. .:.: . . ::. :...
NP_001 IVK-QISEDAKAPQKKHKVLLQQFNTGDERAQKRQ-PIRGSDEVLFKVYCMDHTYTTIRV
490 500 510 520 530 540
580 590 600 610 620 630
pF1KB3 PVTASVREVMAALAQEDGWTKGQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQ
::..::.::..:.:.. : .: ..::..:.:. . :.:. .: :.: .: :::. .
NP_001 PVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPRE
550 560 570 580 590 600
640 650 660 670 680 690
pF1KB3 EVHELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHL
. : : :.: :::::.. ..:.:.:::: :.: .:: ::: .:..:::....: ...
NP_001 QFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNF
610 620 630 640 650 660
700 710 720 730 740 750
pF1KB3 RDVTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFA
. :::::. :.:::::.:.::.::.::: . :.:::.::::.::: :: ::::::::
NP_001 KK-TTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFA
670 680 690 700 710 720
760 770 780 790 800 810
pF1KB3 VMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMP
...:::: :.:::: :::.:: : .:.:. .: :.::: :::.:::..::: ::.:::::
NP_001 IVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMP
730 740 750 760 770 780
820 830 840 850 860 870
pF1KB3 LLLKDMTFIHEGNHTLVENLINFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHED
::.::::: ::::.:...::.:::::::.: .:: ... ::. :..: ..... :.:
NP_001 LLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQ---PFNPDAAQANKNHQD
790 800 810 820 830
880 890 900 910 920
pF1KB3 SQVARISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELEP
.:: ::.::.:::::: ::..:..:::
NP_001 ---------------VRS------YVRQLNVIDNQRTLSQMSHRLEPRRP
840 850 860
>>XP_011508807 (OMIM: 606058) PREDICTED: rap guanine nuc (881 aa)
initn: 2380 init1: 846 opt: 2683 Z-score: 2987.5 bits: 564.0 E(85289): 1.2e-159
Smith-Waterman score: 2733; 50.1% identity (76.8% similar) in 857 aa overlap (74-923:50-878)
50 60 70 80 90 100
pF1KB3 VLRRMHRPRSCSYQLLLEHQRPSCIQGLRWTPLTNSEESLDFSESLEQASTERVLRAGRQ
::: . . : .... .. .:..::::.
XP_011 SRHYGRNIDSIWQDFWLLLMVLWKRALTMTTPLIEPHVPLRPANTITKVPSEKILRAGKI
20 30 40 50 60 70
110 120 130 140 150 160
pF1KB3 LHRHLLATCPNLIRDRKYHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDEG
:. .:. :..::::::::. ::::: : :::: .. ::::.:.::. ::::..:
XP_011 LRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDG
80 90 100 110 120 130
170 180 190 200 210
pF1KB3 ALCHVKHDWAFQDRDAQFYRFPGPEPE--PVGTHEM----EEELAEAVALLSQRGPDALL
.: :: .. :::. :::: : : :. :.: .::: ... :::: :::: .
XP_011 VLNHVDQEHHFQDK-YLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHM
140 150 160 170 180 190
220 230 240 250 260 270
pF1KB3 TVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQG
. ::::::::: ..:..:.::::::::..:::..::::::.::.:: :.:.:::::.::
XP_011 RMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQG
200 210 220 230 240 250
280 290 300 310 320 330
pF1KB3 DKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRV
..::::::: ::::::: .:::.: :::::::::.:::::::::::.:.:::::::::::
XP_011 EEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRV
260 270 280 290 300 310
340 350 360 370 380 390
pF1KB3 DKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQGAGPS-RPPTPGRNRYTVMSGTPEKI
::.:::::..::::.:.::.:: . :::::.. : : . . ...:::::::::::
XP_011 DKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKI
320 330 340 350 360 370
400 410 420 430 440 450
pF1KB3 LELLLEAMGPDSSAHDPTETFLSDFLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERST
:: .::.. ... .. :.. :.::.. : ::::..::: ::. :.:..:. :.:::.
XP_011 LEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMD
380 390 400 410 420 430
460 470 480 490 500 510
pF1KB3 YVCNKRQQILRLVSQWVALYGSMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRR
:. :......::: ::.:.::..:. : :. .::... :. :.:. :.:: :: ..
XP_011 YALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEK
440 450 460 470 480 490
520 530 540 550 560 570
pF1KB3 CHRLENGCGNASPQMKARNLPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQL
. . . .:: : . : . . :: . :. .:.: . . ::. :...
XP_011 IVK-QISEDAKAPQKKHKVLLQQFNTGDERAQKRQ-PIRGSDEVLFKVYCMDHTYTTIRV
500 510 520 530 540 550
580 590 600 610 620 630
pF1KB3 PVTASVREVMAALAQEDGWTKGQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQ
::..::.::..:.:.. : .: ..::..:.:. . :.:. .: :.: .: :::. .
XP_011 PVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPRE
560 570 580 590 600 610
640 650 660 670 680 690
pF1KB3 EVHELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHL
. : : :.: :::::.. ..:.:.:::: :.: .:: ::: .:..:::....: ...
XP_011 QFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNF
620 630 640 650 660 670
700 710 720 730 740 750
pF1KB3 RDVTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFA
. :::::. :.:::::.:.::.::.::: . :.:::.::::.::: :: ::::::::
XP_011 KK-TTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFA
680 690 700 710 720 730
760 770 780 790 800 810
pF1KB3 VMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMP
...:::: :.:::: :::.:: : .:.:. .: :.::: :::.:::..::: ::.:::::
XP_011 IVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMP
740 750 760 770 780 790
820 830 840 850 860 870
pF1KB3 LLLKDMTFIHEGNHTLVENLINFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHED
::.::::: ::::.:...::.:::::::.: .:: ... ::. :..: ..... :.:
XP_011 LLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQ---PFNPDAAQANKNHQD
800 810 820 830 840 850
880 890 900 910 920
pF1KB3 SQVARISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELEP
.:: ::.::.:::::: ::..:..:::
XP_011 ---------------VRS------YVRQLNVIDNQRTLSQMSHRLEPRRP
860 870 880
923 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:51:17 2016 done: Thu Nov 3 12:51:19 2016
Total Scan time: 14.180 Total Display time: 0.230
Function used was FASTA [36.3.4 Apr, 2011]