Result of FASTA (omim) for pF1KB3324
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3324, 605 aa
  1>>>pF1KB3324 605 - 605 aa - 605 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6919+/-0.000497; mu= 17.6605+/- 0.030
 mean_var=152.0974+/-34.487, 0's: 0 Z-trim(112.6): 324  B-trim: 1860 in 2/52
 Lambda= 0.103995
 statistics sampled from 21223 (21641) to 21223 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.608), E-opt: 0.2 (0.254), width:  16
 Scan time:  9.390

The best scores are:                                      opt bits E(85289)
NP_378663 (OMIM: 603482) F-box/WD repeat-containin ( 605) 4142 634.6 2.9e-181
XP_006718117 (OMIM: 603482) PREDICTED: F-box/WD re ( 732) 4041 619.6 1.2e-176
XP_016872361 (OMIM: 603482) PREDICTED: F-box/WD re ( 587) 4023 616.7 6.7e-176
XP_016872362 (OMIM: 603482) PREDICTED: F-box/WD re ( 587) 4023 616.7 6.7e-176
XP_016872360 (OMIM: 603482) PREDICTED: F-box/WD re ( 587) 4023 616.7 6.7e-176
NP_003930 (OMIM: 603482) F-box/WD repeat-containin ( 569) 3790 581.8 2.2e-165
XP_016872363 (OMIM: 603482) PREDICTED: F-box/WD re ( 543) 3618 555.9 1.2e-157
NP_001243785 (OMIM: 603482) F-box/WD repeat-contai ( 579) 3608 554.5 3.7e-157
XP_016872359 (OMIM: 603482) PREDICTED: F-box/WD re ( 706) 3608 554.6 4.1e-157
XP_011538622 (OMIM: 603482) PREDICTED: F-box/WD re ( 537) 3403 523.7 6.4e-148
NP_036432 (OMIM: 605651) F-box/WD repeat-containin ( 542) 3049 470.6 6.2e-132
XP_005265913 (OMIM: 605651) PREDICTED: F-box/WD re ( 531) 3040 469.2 1.6e-131
XP_005265912 (OMIM: 605651) PREDICTED: F-box/WD re ( 563) 3040 469.2 1.6e-131
XP_016864770 (OMIM: 605651) PREDICTED: F-box/WD re ( 510) 3036 468.6 2.3e-131
NP_387449 (OMIM: 605651) F-box/WD repeat-containin ( 508) 3026 467.1 6.5e-131
XP_005265915 (OMIM: 605651) PREDICTED: F-box/WD re ( 510) 3026 467.1 6.6e-131
XP_016864769 (OMIM: 605651) PREDICTED: F-box/WD re ( 510) 3026 467.1 6.6e-131
XP_005265914 (OMIM: 605651) PREDICTED: F-box/WD re ( 515) 3026 467.1 6.6e-131
NP_387448 (OMIM: 605651) F-box/WD repeat-containin ( 529) 3026 467.1 6.7e-131
XP_016864768 (OMIM: 605651) PREDICTED: F-box/WD re ( 542) 3026 467.1 6.8e-131
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540)  450 80.6 1.5e-14
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589)  450 80.7 1.6e-14
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627)  450 80.7 1.6e-14
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679)  450 80.8 1.7e-14
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679)  450 80.8 1.7e-14
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  450 80.8 1.8e-14
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  450 80.8 1.8e-14
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707)  450 80.8 1.8e-14
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  450 80.8 1.8e-14
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  450 80.8 1.8e-14
NP_008882 (OMIM: 601787) transcription initiation  ( 800)  378 70.1 3.4e-11
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334)  369 68.2 5.1e-11
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334)  369 68.2 5.1e-11
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334)  369 68.2 5.1e-11
NP_004757 (OMIM: 606990) coatomer subunit beta' [H ( 906)  354 66.5 4.4e-10
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655)  348 65.4 6.8e-10
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655)  348 65.4 6.8e-10
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655)  348 65.4 6.8e-10
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658)  348 65.4 6.8e-10
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672)  348 65.4 6.9e-10
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672)  348 65.4 6.9e-10
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672)  348 65.4 6.9e-10
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675)  348 65.4 6.9e-10
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675)  348 65.4 6.9e-10
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675)  348 65.4 6.9e-10
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675)  348 65.4 6.9e-10
XP_011521928 (OMIM: 611679) PREDICTED: F-box/WD re ( 745)  345 65.1   1e-09
XP_016863001 (OMIM: 606990) PREDICTED: coatomer su ( 877)  344 65.0 1.2e-09
XP_016879510 (OMIM: 611679) PREDICTED: F-box/WD re ( 724)  340 64.3 1.7e-09
XP_016879509 (OMIM: 611679) PREDICTED: F-box/WD re ( 856)  340 64.4 1.8e-09


>>NP_378663 (OMIM: 603482) F-box/WD repeat-containing pr  (605 aa)
 initn: 4142 init1: 4142 opt: 4142  Z-score: 3375.3  bits: 634.6 E(85289): 2.9e-181
Smith-Waterman score: 4142; 100.0% identity (100.0% similar) in 605 aa overlap (1-605:1-605)

               10        20        30        40        50        60
pF1KB3 MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQNSSEREDC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_378 MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQNSSEREDC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_378 NNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_378 PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_378 ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_378 GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_378 ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_378 SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_378 VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_378 SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_378 APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY
              550       560       570       580       590       600

            
pF1KB3 TYISR
       :::::
NP_378 TYISR
            

>>XP_006718117 (OMIM: 603482) PREDICTED: F-box/WD repeat  (732 aa)
 initn: 4128 init1: 4041 opt: 4041  Z-score: 3292.6  bits: 619.6 E(85289): 1.2e-176
Smith-Waterman score: 4041; 100.0% identity (100.0% similar) in 589 aa overlap (17-605:144-732)

                             10        20        30        40      
pF1KB3               MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTG
                                     ::::::::::::::::::::::::::::::
XP_006 AWGLLLKSGGSSLEKRREAAGGAFLVSGLPCSMPRSLWLGCSSLADSMPSLRCLYNPGTG
           120       130       140       150       160       170   

         50        60        70        80        90       100      
pF1KB3 ALTAFQNSSEREDCNNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALTAFQNSSEREDCNNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCV
           180       190       200       210       220       230   

        110       120       130       140       150       160      
pF1KB3 AKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHG
           240       250       260       270       280       290   

        170       180       190       200       210       220      
pF1KB3 HINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWK
           300       310       320       330       340       350   

        230       240       250       260       270       280      
pF1KB3 KLIERMVRTDSLWRGLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLIERMVRTDSLWRGLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNW
           360       370       380       390       400       410   

        290       300       310       320       330       340      
pF1KB3 RCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV
           420       430       440       450       460       470   

        350       360       370       380       390       400      
pF1KB3 LCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIA
           480       490       500       510       520       530   

        410       420       430       440       450       460      
pF1KB3 VWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHK
           540       550       560       570       580       590   

        470       480       490       500       510       520      
pF1KB3 RGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDG
           600       610       620       630       640       650   

        530       540       550       560       570       580      
pF1KB3 KIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDP
           660       670       680       690       700       710   

        590       600     
pF1KB3 AAQAEPPRSPSRTYTYISR
       :::::::::::::::::::
XP_006 AAQAEPPRSPSRTYTYISR
           720       730  

>>XP_016872361 (OMIM: 603482) PREDICTED: F-box/WD repeat  (587 aa)
 initn: 4023 init1: 4023 opt: 4023  Z-score: 3279.0  bits: 616.7 E(85289): 6.7e-176
Smith-Waterman score: 4023; 100.0% identity (100.0% similar) in 587 aa overlap (19-605:1-587)

               10        20        30        40        50        60
pF1KB3 MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQNSSEREDC
                         ::::::::::::::::::::::::::::::::::::::::::
XP_016                   MPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQNSSEREDC
                                 10        20        30        40  

               70        80        90       100       110       120
pF1KB3 NNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV
             50        60        70        80        90       100  

              130       140       150       160       170       180
pF1KB3 PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF
            110       120       130       140       150       160  

              190       200       210       220       230       240
pF1KB3 ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR
            170       180       190       200       210       220  

              250       260       270       280       290       300
pF1KB3 GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS
            230       240       250       260       270       280  

              310       320       330       340       350       360
pF1KB3 ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS
            290       300       310       320       330       340  

              370       380       390       400       410       420
pF1KB3 SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR
            350       360       370       380       390       400  

              430       440       450       460       470       480
pF1KB3 VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV
            410       420       430       440       450       460  

              490       500       510       520       530       540
pF1KB3 SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR
            470       480       490       500       510       520  

              550       560       570       580       590       600
pF1KB3 APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY
            530       540       550       560       570       580  

            
pF1KB3 TYISR
       :::::
XP_016 TYISR
            

>>XP_016872362 (OMIM: 603482) PREDICTED: F-box/WD repeat  (587 aa)
 initn: 4023 init1: 4023 opt: 4023  Z-score: 3279.0  bits: 616.7 E(85289): 6.7e-176
Smith-Waterman score: 4023; 100.0% identity (100.0% similar) in 587 aa overlap (19-605:1-587)

               10        20        30        40        50        60
pF1KB3 MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQNSSEREDC
                         ::::::::::::::::::::::::::::::::::::::::::
XP_016                   MPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQNSSEREDC
                                 10        20        30        40  

               70        80        90       100       110       120
pF1KB3 NNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV
             50        60        70        80        90       100  

              130       140       150       160       170       180
pF1KB3 PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF
            110       120       130       140       150       160  

              190       200       210       220       230       240
pF1KB3 ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR
            170       180       190       200       210       220  

              250       260       270       280       290       300
pF1KB3 GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS
            230       240       250       260       270       280  

              310       320       330       340       350       360
pF1KB3 ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS
            290       300       310       320       330       340  

              370       380       390       400       410       420
pF1KB3 SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR
            350       360       370       380       390       400  

              430       440       450       460       470       480
pF1KB3 VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV
            410       420       430       440       450       460  

              490       500       510       520       530       540
pF1KB3 SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR
            470       480       490       500       510       520  

              550       560       570       580       590       600
pF1KB3 APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY
            530       540       550       560       570       580  

            
pF1KB3 TYISR
       :::::
XP_016 TYISR
            

>>XP_016872360 (OMIM: 603482) PREDICTED: F-box/WD repeat  (587 aa)
 initn: 4023 init1: 4023 opt: 4023  Z-score: 3279.0  bits: 616.7 E(85289): 6.7e-176
Smith-Waterman score: 4023; 100.0% identity (100.0% similar) in 587 aa overlap (19-605:1-587)

               10        20        30        40        50        60
pF1KB3 MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQNSSEREDC
                         ::::::::::::::::::::::::::::::::::::::::::
XP_016                   MPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQNSSEREDC
                                 10        20        30        40  

               70        80        90       100       110       120
pF1KB3 NNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV
             50        60        70        80        90       100  

              130       140       150       160       170       180
pF1KB3 PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF
            110       120       130       140       150       160  

              190       200       210       220       230       240
pF1KB3 ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR
            170       180       190       200       210       220  

              250       260       270       280       290       300
pF1KB3 GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS
            230       240       250       260       270       280  

              310       320       330       340       350       360
pF1KB3 ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS
            290       300       310       320       330       340  

              370       380       390       400       410       420
pF1KB3 SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR
            350       360       370       380       390       400  

              430       440       450       460       470       480
pF1KB3 VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV
            410       420       430       440       450       460  

              490       500       510       520       530       540
pF1KB3 SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR
            470       480       490       500       510       520  

              550       560       570       580       590       600
pF1KB3 APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY
            530       540       550       560       570       580  

            
pF1KB3 TYISR
       :::::
XP_016 TYISR
            

>>NP_003930 (OMIM: 603482) F-box/WD repeat-containing pr  (569 aa)
 initn: 3790 init1: 3790 opt: 3790  Z-score: 3090.2  bits: 581.8 E(85289): 2.2e-165
Smith-Waterman score: 3801; 94.0% identity (94.0% similar) in 605 aa overlap (1-605:1-569)

               10        20        30        40        50        60
pF1KB3 MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQNSSEREDC
       ::::::::::::::::                                    ::::::::
NP_003 MDPAEAVLQEKALKFM------------------------------------NSSEREDC
               10                                            20    

               70        80        90       100       110       120
pF1KB3 NNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV
           30        40        50        60        70        80    

              130       140       150       160       170       180
pF1KB3 PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF
           90       100       110       120       130       140    

              190       200       210       220       230       240
pF1KB3 ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR
          150       160       170       180       190       200    

              250       260       270       280       290       300
pF1KB3 GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS
          210       220       230       240       250       260    

              310       320       330       340       350       360
pF1KB3 ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS
          270       280       290       300       310       320    

              370       380       390       400       410       420
pF1KB3 SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR
          330       340       350       360       370       380    

              430       440       450       460       470       480
pF1KB3 VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV
          390       400       410       420       430       440    

              490       500       510       520       530       540
pF1KB3 SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR
          450       460       470       480       490       500    

              550       560       570       580       590       600
pF1KB3 APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY
          510       520       530       540       550       560    

            
pF1KB3 TYISR
       :::::
NP_003 TYISR
            

>>XP_016872363 (OMIM: 603482) PREDICTED: F-box/WD repeat  (543 aa)
 initn: 3618 init1: 3618 opt: 3618  Z-score: 2951.0  bits: 555.9 E(85289): 1.2e-157
Smith-Waterman score: 3618; 97.8% identity (98.7% similar) in 542 aa overlap (64-605:2-543)

            40        50        60        70        80        90   
pF1KB3 MPSLRCLYNPGTGALTAFQNSSEREDCNNGEPPRKIIPEKNSLRQTYNSCARLCLNQETV
                                     .: . .. ::    .:::::::::::::::
XP_016                              MDPAEAVLQEKALKFMTYNSCARLCLNQETV
                                            10        20        30 

           100       110       120       130       140       150   
pF1KB3 CLASTAMKTENCVAKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLASTAMKTENCVAKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFV
              40        50        60        70        80        90 

           160       170       180       190       200       210   
pF1KB3 EHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCK
             100       110       120       130       140       150 

           220       230       240       250       260       270   
pF1KB3 EWYRVTSDGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFKNKPPDGNAPPNSFYRALYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWYRVTSDGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFKNKPPDGNAPPNSFYRALYP
             160       170       180       190       200       210 

           280       290       300       310       320       330   
pF1KB3 KIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTL
             220       230       240       250       260       270 

           340       350       360       370       380       390   
pF1KB3 ECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNN
             280       290       300       310       320       330 

           400       410       420       430       440       450   
pF1KB3 GMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNT
             340       350       360       370       380       390 

           460       470       480       490       500       510   
pF1KB3 STCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR
             400       410       420       430       440       450 

           520       530       540       550       560       570   
pF1KB3 FDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSH
             460       470       480       490       500       510 

           580       590       600     
pF1KB3 DDTILIWDFLNDPAAQAEPPRSPSRTYTYISR
       ::::::::::::::::::::::::::::::::
XP_016 DDTILIWDFLNDPAAQAEPPRSPSRTYTYISR
             520       530       540   

>>NP_001243785 (OMIM: 603482) F-box/WD repeat-containing  (579 aa)
 initn: 3608 init1: 3608 opt: 3608  Z-score: 2942.6  bits: 554.5 E(85289): 3.7e-157
Smith-Waterman score: 3899; 95.7% identity (95.7% similar) in 605 aa overlap (1-605:1-579)

               10        20        30        40        50        60
pF1KB3 MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQNSSEREDC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::        
NP_001 MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQ--------
               10        20        30        40        50          

               70        80        90       100       110       120
pF1KB3 NNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV
                         ::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------------TYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV
                               60        70        80        90    

              130       140       150       160       170       180
pF1KB3 PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF
          100       110       120       130       140       150    

              190       200       210       220       230       240
pF1KB3 ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR
          160       170       180       190       200       210    

              250       260       270       280       290       300
pF1KB3 GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS
          220       230       240       250       260       270    

              310       320       330       340       350       360
pF1KB3 ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS
          280       290       300       310       320       330    

              370       380       390       400       410       420
pF1KB3 SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR
          340       350       360       370       380       390    

              430       440       450       460       470       480
pF1KB3 VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV
          400       410       420       430       440       450    

              490       500       510       520       530       540
pF1KB3 SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR
          460       470       480       490       500       510    

              550       560       570       580       590       600
pF1KB3 APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY
          520       530       540       550       560       570    

            
pF1KB3 TYISR
       :::::
NP_001 TYISR
            

>>XP_016872359 (OMIM: 603482) PREDICTED: F-box/WD repeat  (706 aa)
 initn: 3695 init1: 3608 opt: 3608  Z-score: 2941.6  bits: 554.6 E(85289): 4.1e-157
Smith-Waterman score: 3798; 95.6% identity (95.6% similar) in 589 aa overlap (17-605:144-706)

                             10        20        30        40      
pF1KB3               MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTG
                                     ::::::::::::::::::::::::::::::
XP_016 AWGLLLKSGGSSLEKRREAAGGAFLVSGLPCSMPRSLWLGCSSLADSMPSLRCLYNPGTG
           120       130       140       150       160       170   

         50        60        70        80        90       100      
pF1KB3 ALTAFQNSSEREDCNNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCV
       ::::::                          ::::::::::::::::::::::::::::
XP_016 ALTAFQ--------------------------TYNSCARLCLNQETVCLASTAMKTENCV
                                     180       190       200       

        110       120       130       140       150       160      
pF1KB3 AKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHG
       210       220       230       240       250       260       

        170       180       190       200       210       220      
pF1KB3 HINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWK
       270       280       290       300       310       320       

        230       240       250       260       270       280      
pF1KB3 KLIERMVRTDSLWRGLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLIERMVRTDSLWRGLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNW
       330       340       350       360       370       380       

        290       300       310       320       330       340      
pF1KB3 RCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV
       390       400       410       420       430       440       

        350       360       370       380       390       400      
pF1KB3 LCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIA
       450       460       470       480       490       500       

        410       420       430       440       450       460      
pF1KB3 VWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHK
       510       520       530       540       550       560       

        470       480       490       500       510       520      
pF1KB3 RGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDG
       570       580       590       600       610       620       

        530       540       550       560       570       580      
pF1KB3 KIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDP
       630       640       650       660       670       680       

        590       600     
pF1KB3 AAQAEPPRSPSRTYTYISR
       :::::::::::::::::::
XP_016 AAQAEPPRSPSRTYTYISR
       690       700      

>>XP_011538622 (OMIM: 603482) PREDICTED: F-box/WD repeat  (537 aa)
 initn: 3403 init1: 3403 opt: 3403  Z-score: 2776.7  bits: 523.7 E(85289): 6.4e-148
Smith-Waterman score: 3403; 99.6% identity (99.8% similar) in 500 aa overlap (106-605:38-537)

          80        90       100       110       120       130     
pF1KB3 LRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIVPKQRKLSASYEKEKE
                                     :. :::::::::::::::::::::::::::
XP_011 VGVTLRVTSDLKRDTKGASESRDDLFLDLGVGYTKLANGTSSMIVPKQRKLSASYEKEKE
        10        20        30        40        50        60       

         140       150       160       170       180       190     
pF1KB3 LCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAEN
        70        80        90       100       110       120       

         200       210       220       230       240       250     
pF1KB3 ILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFKN
       130       140       150       160       170       180       

         260       270       280       290       300       310     
pF1KB3 KPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQK
       190       200       210       220       230       240       

         320       330       340       350       360       370     
pF1KB3 IVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEM
       250       260       270       280       290       300       

         380       390       400       410       420       430     
pF1KB3 LNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFD
       310       320       330       340       350       360       

         440       450       460       470       480       490     
pF1KB3 DKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIEC
       370       380       390       400       410       420       

         500       510       520       530       540       550     
pF1KB3 GACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHS
       430       440       450       460       470       480       

         560       570       580       590       600     
pF1KB3 GRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTYTYISR
       ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTYTYISR
       490       500       510       520       530       




605 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 19:36:44 2016 done: Sat Nov  5 19:36:45 2016
 Total Scan time:  9.390 Total Display time:  0.120

Function used was FASTA [36.3.4 Apr, 2011]
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