FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3327, 895 aa 1>>>pF1KB3327 895 - 895 aa - 895 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.2353+/-0.00116; mu= 2.3314+/- 0.070 mean_var=394.1928+/-81.938, 0's: 0 Z-trim(114.5): 839 B-trim: 0 in 0/53 Lambda= 0.064598 statistics sampled from 14167 (15072) to 14167 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.748), E-opt: 0.2 (0.463), width: 16 Scan time: 5.270 The best scores are: opt bits E(32554) CCDS1402.1 ZNF281 gene_id:23528|Hs108|chr1 ( 895) 5974 571.6 2.2e-162 CCDS60384.1 ZNF281 gene_id:23528|Hs108|chr1 ( 859) 5392 517.3 4.6e-146 CCDS3031.1 ZNF148 gene_id:7707|Hs108|chr3 ( 794) 715 81.4 7.1e-15 >>CCDS1402.1 ZNF281 gene_id:23528|Hs108|chr1 (895 aa) initn: 5974 init1: 5974 opt: 5974 Z-score: 3028.7 bits: 571.6 E(32554): 2.2e-162 Smith-Waterman score: 5974; 100.0% identity (100.0% similar) in 895 aa overlap (1-895:1-895) 10 20 30 40 50 60 pF1KB3 MKIGSGFLSGGGGTGSSGGSGSGGGGSGGGGGGGSSGRRAEMEPTFPQGMVMFNHRLPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MKIGSGFLSGGGGTGSSGGSGSGGGGSGGGGGGGSSGRRAEMEPTFPQGMVMFNHRLPPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 TSFTRPAGSAAPPPQCVLSSSTSAAPAAEPPPPPAPDMTFKKEPAASAAAFPSQRTSWGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 TSFTRPAGSAAPPPQCVLSSSTSAAPAAEPPPPPAPDMTFKKEPAASAAAFPSQRTSWGF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LQSLVSIKQEKPADPEEQQSHHHHHHHHYGGLFAGAEERSPGLGGGEGGSHGVIQDLSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LQSLVSIKQEKPADPEEQQSHHHHHHHHYGGLFAGAEERSPGLGGGEGGSHGVIQDLSIL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 HQHVQQQPAQHHRDVLLSSSSRTDDHHGTEEPKQDTNVKKAKRPKPESQGIKAKRKPSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 HQHVQQQPAQHHRDVLLSSSSRTDDHHGTEEPKQDTNVKKAKRPKPESQGIKAKRKPSAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 SKPSLVGDGEGAILSPSQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SKPSLVGDGEGAILSPSQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 KYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 KYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LKHRRTCGEVIVKGATSAEPGSSNHTNMGNLAVLSQGNTSSSRRKTKSKSIAIENKEQKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LKHRRTCGEVIVKGATSAEPGSSNHTNMGNLAVLSQGNTSSSRRKTKSKSIAIENKEQKT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GKTNESQISNNINMQSYSVEMPTVSSSGGIIGTGIDELQKRVPKLIFKKGSRKNTDKNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GKTNESQISNNINMQSYSVEMPTVSSSGGIIGTGIDELQKRVPKLIFKKGSRKNTDKNYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 NFVSPLPDIVGQKSLSGKPSGSLGIVSNNSVETIGLLQSTSGKQGQISSNYDDAMQFSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 NFVSPLPDIVGQKSLSGKPSGSLGIVSNNSVETIGLLQSTSGKQGQISSNYDDAMQFSKK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 RRYLPTASSNSAFSINVGHMVSQQSVIQSAGVSVLDNEAPLSLIDSSALNAEIKSCHDKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 RRYLPTASSNSAFSINVGHMVSQQSVIQSAGVSVLDNEAPLSLIDSSALNAEIKSCHDKS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 GIPDEVLQSILDQYSNKSESQKEDPFNIAEPRVDLHTSGEHSELVQEENLSPGTQTPSND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GIPDEVLQSILDQYSNKSESQKEDPFNIAEPRVDLHTSGEHSELVQEENLSPGTQTPSND 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 KASMLQEYSKYLQQAFEKSTNASFTLGHGFQFVSLSSPLHNHTLFPEKQIYTTSPLECGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 KASMLQEYSKYLQQAFEKSTNASFTLGHGFQFVSLSSPLHNHTLFPEKQIYTTSPLECGF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 GQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 FQSSSQKLTSQKEQKNLESSTGFQIPSQELASQIDPQKDIEPRTTYQIENFAQAFGSQFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 FQSSSQKLTSQKEQKNLESSTGFQIPSQELASQIDPQKDIEPRTTYQIENFAQAFGSQFK 790 800 810 820 830 840 850 860 870 880 890 pF1KB3 SGSRVPMTFITNSNGEVDHRVRTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SGSRVPMTFITNSNGEVDHRVRTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR 850 860 870 880 890 >>CCDS60384.1 ZNF281 gene_id:23528|Hs108|chr1 (859 aa) initn: 5713 init1: 5392 opt: 5392 Z-score: 2735.8 bits: 517.3 E(32554): 4.6e-146 Smith-Waterman score: 5645; 96.0% identity (96.0% similar) in 895 aa overlap (1-895:1-859) 10 20 30 40 50 60 pF1KB3 MKIGSGFLSGGGGTGSSGGSGSGGGGSGGGGGGGSSGRRAEMEPTFPQGMVMFNHRLPPV :::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MKIGSGFLSGGGGTGSSGGSGSGGGGSGGGGGGGSSGRRAEMEPTFPQ------------ 10 20 30 40 70 80 90 100 110 120 pF1KB3 TSFTRPAGSAAPPPQCVLSSSTSAAPAAEPPPPPAPDMTFKKEPAASAAAFPSQRTSWGF :::::::::::::::::::::::::::::::::::: CCDS60 ------------------------APAAEPPPPPAPDMTFKKEPAASAAAFPSQRTSWGF 50 60 70 80 130 140 150 160 170 180 pF1KB3 LQSLVSIKQEKPADPEEQQSHHHHHHHHYGGLFAGAEERSPGLGGGEGGSHGVIQDLSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LQSLVSIKQEKPADPEEQQSHHHHHHHHYGGLFAGAEERSPGLGGGEGGSHGVIQDLSIL 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB3 HQHVQQQPAQHHRDVLLSSSSRTDDHHGTEEPKQDTNVKKAKRPKPESQGIKAKRKPSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 HQHVQQQPAQHHRDVLLSSSSRTDDHHGTEEPKQDTNVKKAKRPKPESQGIKAKRKPSAS 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB3 SKPSLVGDGEGAILSPSQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SKPSLVGDGEGAILSPSQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQ 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB3 KYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 KYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRL 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB3 LKHRRTCGEVIVKGATSAEPGSSNHTNMGNLAVLSQGNTSSSRRKTKSKSIAIENKEQKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LKHRRTCGEVIVKGATSAEPGSSNHTNMGNLAVLSQGNTSSSRRKTKSKSIAIENKEQKT 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB3 GKTNESQISNNINMQSYSVEMPTVSSSGGIIGTGIDELQKRVPKLIFKKGSRKNTDKNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GKTNESQISNNINMQSYSVEMPTVSSSGGIIGTGIDELQKRVPKLIFKKGSRKNTDKNYL 390 400 410 420 430 440 490 500 510 520 530 540 pF1KB3 NFVSPLPDIVGQKSLSGKPSGSLGIVSNNSVETIGLLQSTSGKQGQISSNYDDAMQFSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 NFVSPLPDIVGQKSLSGKPSGSLGIVSNNSVETIGLLQSTSGKQGQISSNYDDAMQFSKK 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB3 RRYLPTASSNSAFSINVGHMVSQQSVIQSAGVSVLDNEAPLSLIDSSALNAEIKSCHDKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RRYLPTASSNSAFSINVGHMVSQQSVIQSAGVSVLDNEAPLSLIDSSALNAEIKSCHDKS 510 520 530 540 550 560 610 620 630 640 650 660 pF1KB3 GIPDEVLQSILDQYSNKSESQKEDPFNIAEPRVDLHTSGEHSELVQEENLSPGTQTPSND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GIPDEVLQSILDQYSNKSESQKEDPFNIAEPRVDLHTSGEHSELVQEENLSPGTQTPSND 570 580 590 600 610 620 670 680 690 700 710 720 pF1KB3 KASMLQEYSKYLQQAFEKSTNASFTLGHGFQFVSLSSPLHNHTLFPEKQIYTTSPLECGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 KASMLQEYSKYLQQAFEKSTNASFTLGHGFQFVSLSSPLHNHTLFPEKQIYTTSPLECGF 630 640 650 660 670 680 730 740 750 760 770 780 pF1KB3 GQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSA 690 700 710 720 730 740 790 800 810 820 830 840 pF1KB3 FQSSSQKLTSQKEQKNLESSTGFQIPSQELASQIDPQKDIEPRTTYQIENFAQAFGSQFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 FQSSSQKLTSQKEQKNLESSTGFQIPSQELASQIDPQKDIEPRTTYQIENFAQAFGSQFK 750 760 770 780 790 800 850 860 870 880 890 pF1KB3 SGSRVPMTFITNSNGEVDHRVRTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SGSRVPMTFITNSNGEVDHRVRTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR 810 820 830 840 850 >>CCDS3031.1 ZNF148 gene_id:7707|Hs108|chr3 (794 aa) initn: 951 init1: 679 opt: 715 Z-score: 380.5 bits: 81.4 E(32554): 7.1e-15 Smith-Waterman score: 1369; 40.2% identity (68.7% similar) in 614 aa overlap (209-785:121-728) 180 190 200 210 220 230 pF1KB3 ILHQHVQQQPAQHHRDVLLSSSSRTDDHHGTEEPKQDTNVKKAKRPKPESQGIKAKRKPS :. .: :: : .: . : ::: CCDS30 EEQMETHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQIR-EPVDLQKKKKRKQR 100 110 120 130 140 240 250 260 270 280 290 pF1KB3 ASSKPSLVGDGEGAILSPSQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGF . .: ... .:.. . : :.:.::.::::..:::.:::.:::::.:::::::.: : CCDS30 SPAKILTINE-DGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRF 150 160 170 180 190 200 300 310 320 330 340 350 pF1KB3 IQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTD :::::::::::::. :::: ::.:.:.::::::::::::::::::::.:. : ::::::: CCDS30 IQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTD 210 220 230 240 250 260 360 370 380 390 400 pF1KB3 RLLKHRRTCGE--------VIVKGATSAEPGSSNHTNMGNLAVLSQGNTSSSRRKTKS-- :.:::.: : : .::. . .:. .. . : . . .....:... CCDS30 RVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKTEKKSSGMD 270 280 290 300 310 320 410 420 430 440 450 460 pF1KB3 KSIAIENKEQKTGK-------TNESQISNNINMQSYSVEMPTVSSSGGIIGTGIDELQKR : :..... : : .. ...... . :.:::: : .:. . . :.. CCDS30 KESALDKSDLKKDKNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASGEIHP- 330 340 350 360 370 380 470 480 490 500 510 pF1KB3 VPKLIFKKGSRKNTDKNYLN---FVSPLPDIVGQK------SLSGKPSGSLGIVSNNSVE :::..:: . : . :. :. .::: .: : : . : .: ... CCDS30 -PKLVLKKINSKRSLKQPLEQNQTISPLSTYEESKVSKYAFELVDKQA-LLDSEGNADID 390 400 410 420 430 440 520 530 540 550 560 570 pF1KB3 TIGLLQSTSGKQGQISSNYDDAMQFSKKRRYLPTASSNS-AFSINVGHMVSQQSVIQSAG . :: .: . :.:::::::: ::.::: .::.:: ...::: ..:: :: :.: CCDS30 QVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVGTIASQPSVTQAAV 450 460 470 480 490 500 580 590 600 610 620 630 pF1KB3 VSVLDNEAPLSLIDSSALNAEIKSCHDKSGIPDEVLQSILDQYSNKSESQKEDPFNIAEP .::.:. . :...:.:::.:::: :::. :::::::..::.::.:...:.: :..:. CCDS30 ASVIDESTTASILESQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADT 510 520 530 540 550 560 640 650 660 670 680 pF1KB3 RVDLH---TSGEHSELVQEENLSPGTQTPSNDKASMLQEYSKYLQQAFEKST-NASFTLG .: .:.: :.. ::.. ..:. :.:::.:::::::.::::..... : .. . CCDS30 EVTSSISINSSEVPEVTPSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNS 570 580 590 600 610 620 690 700 710 720 730 740 pF1KB3 HGFQFVSLSSPLHNHTLFP--EKQIYTTSPLECGFGQSVTSVLPSSLPKPPFGMLFG-SQ ...::. .. : :. : .::.:.: :.. .: ....: : .. : ::.. : :: CCDS30 PSLNFVTDNQTLPNQPAFSSIDKQVYATMPIN-SFRSGMNSPLRTTPDKSHFGLIVGDSQ 630 640 650 660 670 680 750 760 770 780 790 800 pF1KB3 PGLYLSALDATHQQLTPSQELDDLIDSQKNLETS---SAFQSSSQKLTSQKEQKNLESST .. .:. ...: . : .:.. : . :::. :.. .:.: :: CCDS30 HSFPFSGDETNHASATSTQDFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGI 690 700 710 720 730 740 810 820 830 840 850 860 pF1KB3 GFQIPSQELASQIDPQKDIEPRTTYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRV CCDS30 ATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG 750 760 770 780 790 895 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:52:44 2016 done: Thu Nov 3 12:52:45 2016 Total Scan time: 5.270 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]