FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3331, 514 aa
1>>>pF1KB3331 514 - 514 aa - 514 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3133+/-0.00048; mu= 9.6042+/- 0.030
mean_var=212.4812+/-45.940, 0's: 0 Z-trim(114.6): 399 B-trim: 362 in 1/54
Lambda= 0.087986
statistics sampled from 24077 (24576) to 24077 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.288), width: 16
Scan time: 9.520
The best scores are: opt bits E(85289)
NP_002660 (OMIM: 605961) pleiotropic regulator 1 i ( 514) 3484 455.9 1.3e-127
NP_001188493 (OMIM: 605961) pleiotropic regulator ( 505) 2770 365.2 2.5e-100
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 501 77.0 9.7e-14
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 501 77.0 9.7e-14
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 501 77.0 9.7e-14
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 462 72.4 4.6e-12
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 462 72.4 4.6e-12
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 462 72.4 4.6e-12
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 462 72.4 4.6e-12
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 462 72.4 4.7e-12
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 462 72.4 4.7e-12
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672) 462 72.4 4.7e-12
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675) 462 72.4 4.7e-12
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675) 462 72.4 4.7e-12
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675) 462 72.4 4.7e-12
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675) 462 72.4 4.7e-12
XP_016880191 (OMIM: 601545,607432) PREDICTED: plat ( 345) 392 63.2 1.4e-09
XP_016880190 (OMIM: 601545,607432) PREDICTED: plat ( 410) 392 63.3 1.6e-09
XP_016880189 (OMIM: 601545,607432) PREDICTED: plat ( 410) 392 63.3 1.6e-09
NP_000421 (OMIM: 601545,607432) platelet-activatin ( 410) 392 63.3 1.6e-09
XP_016880188 (OMIM: 601545,607432) PREDICTED: plat ( 410) 392 63.3 1.6e-09
XP_011522204 (OMIM: 601545,607432) PREDICTED: plat ( 428) 392 63.3 1.7e-09
XP_011522203 (OMIM: 601545,607432) PREDICTED: plat ( 428) 392 63.3 1.7e-09
XP_011522205 (OMIM: 601545,607432) PREDICTED: plat ( 428) 392 63.3 1.7e-09
NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 388 62.6 1.8e-09
NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 388 62.6 1.8e-09
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540) 390 63.2 2.3e-09
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589) 390 63.2 2.4e-09
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627) 390 63.2 2.5e-09
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 390 63.3 2.7e-09
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 390 63.3 2.7e-09
NP_001231855 (OMIM: 607795,615922) U4/U6 small nuc ( 521) 388 62.9 2.7e-09
NP_004688 (OMIM: 607795,615922) U4/U6 small nuclea ( 522) 388 62.9 2.7e-09
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 390 63.3 2.7e-09
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 390 63.3 2.7e-09
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 390 63.3 2.7e-09
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707) 390 63.3 2.7e-09
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 390 63.3 2.7e-09
XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374) 364 59.7 1.8e-08
XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321) 360 59.1 2.3e-08
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 360 59.1 2.5e-08
NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369) 360 59.2 2.5e-08
NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 360 59.2 2.7e-08
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300) 352 58.0 4.5e-08
XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326) 352 58.1 4.7e-08
NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436) 332 55.7 3.3e-07
NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478) 332 55.7 3.5e-07
XP_016860391 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 320 54.0 7.8e-07
XP_011510137 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 320 54.0 7.8e-07
XP_016860389 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 320 54.0 7.8e-07
>>NP_002660 (OMIM: 605961) pleiotropic regulator 1 isofo (514 aa)
initn: 3484 init1: 3484 opt: 3484 Z-score: 2411.9 bits: 455.9 E(85289): 1.3e-127
Smith-Waterman score: 3484; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514)
10 20 30 40 50 60
pF1KB3 MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SKENLKEKGPQNATDSYVHKQYPANQGQEVEYFVAGTHPYPPGPGVALTADTKIQRMPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SKENLKEKGPQNATDSYVHKQYPANQGQEVEYFVAGTHPYPPGPGVALTADTKIQRMPSE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SAAQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SAAQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 SLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 AGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 VNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTA
430 440 450 460 470 480
490 500 510
pF1KB3 EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
::::::::::::::::::::::::::::::::::
NP_002 EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
490 500 510
>>NP_001188493 (OMIM: 605961) pleiotropic regulator 1 is (505 aa)
initn: 2770 init1: 2770 opt: 2770 Z-score: 1922.2 bits: 365.2 E(85289): 2.5e-100
Smith-Waterman score: 3377; 98.2% identity (98.2% similar) in 514 aa overlap (1-514:1-505)
10 20 30 40 50 60
pF1KB3 MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SKENLKEKGPQNATDSYVHKQYPANQGQEVEYFVAGTHPYPPGPGVALTADTKIQRMPSE
:::::::::::::::::::::::::::::::::::: :::::::::::::::
NP_001 SKENLKEKGPQNATDSYVHKQYPANQGQEVEYFVAG---------VALTADTKIQRMPSE
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 SAAQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAAQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 KAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 SLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 AGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLT
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 VNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTA
420 430 440 450 460 470
490 500 510
pF1KB3 EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
::::::::::::::::::::::::::::::::::
NP_001 EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
480 490 500
>>NP_060058 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 371 init1: 371 opt: 501 Z-score: 367.7 bits: 77.0 E(85289): 9.7e-14
Smith-Waterman score: 501; 26.7% identity (60.6% similar) in 348 aa overlap (153-492:2-333)
130 140 150 160 170 180
pF1KB3 AQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAKKA
:... .: . . .. : .. :: ..: .
NP_060 MATEEKKPETEAARAQPTPSS--SATQSKPT
10 20
190 200 210 220 230 240
pF1KB3 PTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSL
:. :. . : ...:: : . :...:....:::. :::: .::.. ..
NP_060 PVKPN------YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTI
30 40 50 60 70 80
250 260 270 280 290 300
pF1KB3 TGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDV
.:: . : :. : : : ..:: .: ::. .: .. .:: . :. ...: ..
NP_060 SGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNL
90 100 110 120 130 140
310 320 330 340 350 360
pF1KB3 LVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAG
.:. : : ..:::::.: ..:: .:.. :..:. . :...:.: :.:: ..:
NP_060 IVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG
150 160 170 180 190 200
370 380 390 400 410
pF1KB3 KTRVTLTNHKKS-VRAVVLHPR-HYTFASGSPDNIKQWKFPDGSFIQNLSGHNA----II
. :: . . : : . : .: .:. ...: : . :. ... .::. :.
NP_060 QCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIF
210 220 230 240 250 260
420 430 440 450 460 470
pF1KB3 NTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESR
...:.. .:::.... ...:. .: :... : : ... : .:.
NP_060 ANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ-----GHTDV---VISTACHPTENI
270 280 290 300 310
480 490 500 510
pF1KB3 LLTA--EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
. .: : :::::... :
NP_060 IASAALENDKTIKLWKSDC
320 330
>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta (334 aa)
initn: 371 init1: 371 opt: 501 Z-score: 367.7 bits: 77.0 E(85289): 9.7e-14
Smith-Waterman score: 501; 26.7% identity (60.6% similar) in 348 aa overlap (153-492:2-333)
130 140 150 160 170 180
pF1KB3 AQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAKKA
:... .: . . .. : .. :: ..: .
XP_005 MATEEKKPETEAARAQPTPSS--SATQSKPT
10 20
190 200 210 220 230 240
pF1KB3 PTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSL
:. :. . : ...:: : . :...:....:::. :::: .::.. ..
XP_005 PVKPN------YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTI
30 40 50 60 70 80
250 260 270 280 290 300
pF1KB3 TGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDV
.:: . : :. : : : ..:: .: ::. .: .. .:: . :. ...: ..
XP_005 SGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNL
90 100 110 120 130 140
310 320 330 340 350 360
pF1KB3 LVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAG
.:. : : ..:::::.: ..:: .:.. :..:. . :...:.: :.:: ..:
XP_005 IVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG
150 160 170 180 190 200
370 380 390 400 410
pF1KB3 KTRVTLTNHKKS-VRAVVLHPR-HYTFASGSPDNIKQWKFPDGSFIQNLSGHNA----II
. :: . . : : . : .: .:. ...: : . :. ... .::. :.
XP_005 QCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIF
210 220 230 240 250 260
420 430 440 450 460 470
pF1KB3 NTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESR
...:.. .:::.... ...:. .: :... : : ... : .:.
XP_005 ANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ-----GHTDV---VISTACHPTENI
270 280 290 300 310
480 490 500 510
pF1KB3 LLTA--EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
. .: : :::::... :
XP_005 IASAALENDKTIKLWKSDC
320 330
>>NP_438172 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 371 init1: 371 opt: 501 Z-score: 367.7 bits: 77.0 E(85289): 9.7e-14
Smith-Waterman score: 501; 26.7% identity (60.6% similar) in 348 aa overlap (153-492:2-333)
130 140 150 160 170 180
pF1KB3 AQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAKKA
:... .: . . .. : .. :: ..: .
NP_438 MATEEKKPETEAARAQPTPSS--SATQSKPT
10 20
190 200 210 220 230 240
pF1KB3 PTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSL
:. :. . : ...:: : . :...:....:::. :::: .::.. ..
NP_438 PVKPN------YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTI
30 40 50 60 70 80
250 260 270 280 290 300
pF1KB3 TGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDV
.:: . : :. : : : ..:: .: ::. .: .. .:: . :. ...: ..
NP_438 SGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNL
90 100 110 120 130 140
310 320 330 340 350 360
pF1KB3 LVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAG
.:. : : ..:::::.: ..:: .:.. :..:. . :...:.: :.:: ..:
NP_438 IVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG
150 160 170 180 190 200
370 380 390 400 410
pF1KB3 KTRVTLTNHKKS-VRAVVLHPR-HYTFASGSPDNIKQWKFPDGSFIQNLSGHNA----II
. :: . . : : . : .: .:. ...: : . :. ... .::. :.
NP_438 QCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIF
210 220 230 240 250 260
420 430 440 450 460 470
pF1KB3 NTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESR
...:.. .:::.... ...:. .: :... : : ... : .:.
NP_438 ANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ-----GHTDV---VISTACHPTENI
270 280 290 300 310
480 490 500 510
pF1KB3 LLTA--EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
. .: : :::::... :
NP_438 IASAALENDKTIKLWKSDC
320 330
>>XP_016878353 (OMIM: 602703,616212) PREDICTED: katanin (655 aa)
initn: 728 init1: 409 opt: 462 Z-score: 337.5 bits: 72.4 E(85289): 4.6e-12
Smith-Waterman score: 462; 28.5% identity (63.1% similar) in 260 aa overlap (194-450:11-268)
170 180 190 200 210 220
pF1KB3 SIVMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAV-EPGNQWFVTG
::: .... : . : ... . ... ..::
XP_016 MATPVVTKTAWKLQEIVA-HASNVSSLVLGKASGRLLATG
10 20 30
230 240 250 260 270 280
pF1KB3 SADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR
. : ...:.. . . .::::: : :..: ..: . . ... ... :::: :..:
XP_016 GDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILR
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB3 HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAE
:: . . .::.:: . ... :.:.. ..::.: :. : ::..:: .: .
XP_016 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDG
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB3 PQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFP
. ... : :..::::.::: . .: : .: .:: .: .:::: : .:. : .
XP_016 KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE
160 170 180 190 200 210
410 420 430 440 450 460
pF1KB3 DGSFIQNLSGHNAIINTLTVNSDGV-LVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLD
. .. . :. . . .. : :: : :: .. ..... :. :. :
XP_016 KFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPERCFDVVLVNWGKVADL
220 230 240 250 260 270
470 480 490 500 510
pF1KB3 SESGIFACAFDQSESRLLTAEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
XP_016 AICNDQLIGVAFSQSNVSSYVVDLTRVTRTGTVARDPVQDHRPLAQPLPNPSAPLRRIYE
280 290 300 310 320 330
>>NP_005877 (OMIM: 602703,616212) katanin p80 WD40 repea (655 aa)
initn: 728 init1: 409 opt: 462 Z-score: 337.5 bits: 72.4 E(85289): 4.6e-12
Smith-Waterman score: 462; 28.5% identity (63.1% similar) in 260 aa overlap (194-450:11-268)
170 180 190 200 210 220
pF1KB3 SIVMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAV-EPGNQWFVTG
::: .... : . : ... . ... ..::
NP_005 MATPVVTKTAWKLQEIVA-HASNVSSLVLGKASGRLLATG
10 20 30
230 240 250 260 270 280
pF1KB3 SADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR
. : ...:.. . . .::::: : :..: ..: . . ... ... :::: :..:
NP_005 GDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILR
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB3 HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAE
:: . . .::.:: . ... :.:.. ..::.: :. : ::..:: .: .
NP_005 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDG
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB3 PQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFP
. ... : :..::::.::: . .: : .: .:: .: .:::: : .:. : .
NP_005 KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE
160 170 180 190 200 210
410 420 430 440 450 460
pF1KB3 DGSFIQNLSGHNAIINTLTVNSDGV-LVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLD
. .. . :. . . .. : :: : :: .. ..... :. :. :
NP_005 KFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPERCFDVVLVNWGKVADL
220 230 240 250 260 270
470 480 490 500 510
pF1KB3 SESGIFACAFDQSESRLLTAEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
NP_005 AICNDQLIGVAFSQSNVSSYVVDLTRVTRTGTVARDPVQDHRPLAQPLPNPSAPLRRIYE
280 290 300 310 320 330
>>XP_016878352 (OMIM: 602703,616212) PREDICTED: katanin (655 aa)
initn: 728 init1: 409 opt: 462 Z-score: 337.5 bits: 72.4 E(85289): 4.6e-12
Smith-Waterman score: 462; 28.5% identity (63.1% similar) in 260 aa overlap (194-450:11-268)
170 180 190 200 210 220
pF1KB3 SIVMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAV-EPGNQWFVTG
::: .... : . : ... . ... ..::
XP_016 MATPVVTKTAWKLQEIVA-HASNVSSLVLGKASGRLLATG
10 20 30
230 240 250 260 270 280
pF1KB3 SADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR
. : ...:.. . . .::::: : :..: ..: . . ... ... :::: :..:
XP_016 GDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILR
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB3 HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAE
:: . . .::.:: . ... :.:.. ..::.: :. : ::..:: .: .
XP_016 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDG
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB3 PQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFP
. ... : :..::::.::: . .: : .: .:: .: .:::: : .:. : .
XP_016 KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE
160 170 180 190 200 210
410 420 430 440 450 460
pF1KB3 DGSFIQNLSGHNAIINTLTVNSDGV-LVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLD
. .. . :. . . .. : :: : :: .. ..... :. :. :
XP_016 KFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPERCFDVVLVNWGKVADL
220 230 240 250 260 270
470 480 490 500 510
pF1KB3 SESGIFACAFDQSESRLLTAEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
XP_016 AICNDQLIGVAFSQSNVSSYVVDLTRVTRTGTVARDPVQDHRPLAQPLPNPSAPLRRIYE
280 290 300 310 320 330
>>XP_006721186 (OMIM: 602703,616212) PREDICTED: katanin (658 aa)
initn: 728 init1: 409 opt: 462 Z-score: 337.5 bits: 72.4 E(85289): 4.6e-12
Smith-Waterman score: 462; 28.5% identity (63.1% similar) in 260 aa overlap (194-450:11-268)
170 180 190 200 210 220
pF1KB3 SIVMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAV-EPGNQWFVTG
::: .... : . : ... . ... ..::
XP_006 MATPVVTKTAWKLQEIVA-HASNVSSLVLGKASGRLLATG
10 20 30
230 240 250 260 270 280
pF1KB3 SADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR
. : ...:.. . . .::::: : :..: ..: . . ... ... :::: :..:
XP_006 GDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILR
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB3 HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAE
:: . . .::.:: . ... :.:.. ..::.: :. : ::..:: .: .
XP_006 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDG
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB3 PQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFP
. ... : :..::::.::: . .: : .: .:: .: .:::: : .:. : .
XP_006 KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE
160 170 180 190 200 210
410 420 430 440 450 460
pF1KB3 DGSFIQNLSGHNAIINTLTVNSDGV-LVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLD
. .. . :. . . .. : :: : :: .. ..... :. :. :
XP_006 KFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPERCFDVVLVNWGKVADL
220 230 240 250 260 270
470 480 490 500 510
pF1KB3 SESGIFACAFDQSESRLLTAEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
XP_006 AICNDQLIGVAFSQSNVSSYVVDLTRVTRTGTVARDPVQDHRPLAQPLPNPSAPLRRIYE
280 290 300 310 320 330
>>XP_016878351 (OMIM: 602703,616212) PREDICTED: katanin (672 aa)
initn: 728 init1: 409 opt: 462 Z-score: 337.4 bits: 72.4 E(85289): 4.7e-12
Smith-Waterman score: 462; 28.5% identity (63.1% similar) in 260 aa overlap (194-450:11-268)
170 180 190 200 210 220
pF1KB3 SIVMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAV-EPGNQWFVTG
::: .... : . : ... . ... ..::
XP_016 MATPVVTKTAWKLQEIVA-HASNVSSLVLGKASGRLLATG
10 20 30
230 240 250 260 270 280
pF1KB3 SADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR
. : ...:.. . . .::::: : :..: ..: . . ... ... :::: :..:
XP_016 GDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILR
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB3 HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAE
:: . . .::.:: . ... :.:.. ..::.: :. : ::..:: .: .
XP_016 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDG
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB3 PQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFP
. ... : :..::::.::: . .: : .: .:: .: .:::: : .:. : .
XP_016 KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE
160 170 180 190 200 210
410 420 430 440 450 460
pF1KB3 DGSFIQNLSGHNAIINTLTVNSDGV-LVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLD
. .. . :. . . .. : :: : :: .. ..... :. :. :
XP_016 KFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPERCFDVVLVNWGKVADL
220 230 240 250 260 270
470 480 490 500 510
pF1KB3 SESGIFACAFDQSESRLLTAEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
XP_016 AICNDQLIGVAFSQSNVSSYVVDLTRVTRTGTVARDPVQDHRPLAQPLPNPSAPLRRIYE
280 290 300 310 320 330
514 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:55:26 2016 done: Sat Nov 5 04:55:28 2016
Total Scan time: 9.520 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]