Result of FASTA (omim) for pF1KB3331
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3331, 514 aa
  1>>>pF1KB3331 514 - 514 aa - 514 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.3133+/-0.00048; mu= 9.6042+/- 0.030
 mean_var=212.4812+/-45.940, 0's: 0 Z-trim(114.6): 399  B-trim: 362 in 1/54
 Lambda= 0.087986
 statistics sampled from 24077 (24576) to 24077 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.288), width:  16
 Scan time:  9.520

The best scores are:                                      opt bits E(85289)
NP_002660 (OMIM: 605961) pleiotropic regulator 1 i ( 514) 3484 455.9 1.3e-127
NP_001188493 (OMIM: 605961) pleiotropic regulator  ( 505) 2770 365.2 2.5e-100
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334)  501 77.0 9.7e-14
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334)  501 77.0 9.7e-14
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334)  501 77.0 9.7e-14
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655)  462 72.4 4.6e-12
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655)  462 72.4 4.6e-12
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655)  462 72.4 4.6e-12
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658)  462 72.4 4.6e-12
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672)  462 72.4 4.7e-12
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672)  462 72.4 4.7e-12
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672)  462 72.4 4.7e-12
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675)  462 72.4 4.7e-12
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675)  462 72.4 4.7e-12
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675)  462 72.4 4.7e-12
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675)  462 72.4 4.7e-12
XP_016880191 (OMIM: 601545,607432) PREDICTED: plat ( 345)  392 63.2 1.4e-09
XP_016880190 (OMIM: 601545,607432) PREDICTED: plat ( 410)  392 63.3 1.6e-09
XP_016880189 (OMIM: 601545,607432) PREDICTED: plat ( 410)  392 63.3 1.6e-09
NP_000421 (OMIM: 601545,607432) platelet-activatin ( 410)  392 63.3 1.6e-09
XP_016880188 (OMIM: 601545,607432) PREDICTED: plat ( 410)  392 63.3 1.6e-09
XP_011522204 (OMIM: 601545,607432) PREDICTED: plat ( 428)  392 63.3 1.7e-09
XP_011522203 (OMIM: 601545,607432) PREDICTED: plat ( 428)  392 63.3 1.7e-09
XP_011522205 (OMIM: 601545,607432) PREDICTED: plat ( 428)  392 63.3 1.7e-09
NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279)  388 62.6 1.8e-09
NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279)  388 62.6 1.8e-09
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540)  390 63.2 2.3e-09
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589)  390 63.2 2.4e-09
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627)  390 63.2 2.5e-09
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679)  390 63.3 2.7e-09
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679)  390 63.3 2.7e-09
NP_001231855 (OMIM: 607795,615922) U4/U6 small nuc ( 521)  388 62.9 2.7e-09
NP_004688 (OMIM: 607795,615922) U4/U6 small nuclea ( 522)  388 62.9 2.7e-09
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  390 63.3 2.7e-09
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  390 63.3 2.7e-09
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  390 63.3 2.7e-09
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707)  390 63.3 2.7e-09
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  390 63.3 2.7e-09
XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374)  364 59.7 1.8e-08
XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321)  360 59.1 2.3e-08
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359)  360 59.1 2.5e-08
NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369)  360 59.2 2.5e-08
NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407)  360 59.2 2.7e-08
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300)  352 58.0 4.5e-08
XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326)  352 58.1 4.7e-08
NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436)  332 55.7 3.3e-07
NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478)  332 55.7 3.5e-07
XP_016860391 (OMIM: 612173) PREDICTED: sperm-assoc ( 323)  320 54.0 7.8e-07
XP_011510137 (OMIM: 612173) PREDICTED: sperm-assoc ( 323)  320 54.0 7.8e-07
XP_016860389 (OMIM: 612173) PREDICTED: sperm-assoc ( 323)  320 54.0 7.8e-07


>>NP_002660 (OMIM: 605961) pleiotropic regulator 1 isofo  (514 aa)
 initn: 3484 init1: 3484 opt: 3484  Z-score: 2411.9  bits: 455.9 E(85289): 1.3e-127
Smith-Waterman score: 3484; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514)

               10        20        30        40        50        60
pF1KB3 MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SKENLKEKGPQNATDSYVHKQYPANQGQEVEYFVAGTHPYPPGPGVALTADTKIQRMPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SKENLKEKGPQNATDSYVHKQYPANQGQEVEYFVAGTHPYPPGPGVALTADTKIQRMPSE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SAAQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SAAQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 KAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 SLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 AGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 VNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTA
              430       440       450       460       470       480

              490       500       510    
pF1KB3 EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
       ::::::::::::::::::::::::::::::::::
NP_002 EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
              490       500       510    

>>NP_001188493 (OMIM: 605961) pleiotropic regulator 1 is  (505 aa)
 initn: 2770 init1: 2770 opt: 2770  Z-score: 1922.2  bits: 365.2 E(85289): 2.5e-100
Smith-Waterman score: 3377; 98.2% identity (98.2% similar) in 514 aa overlap (1-514:1-505)

               10        20        30        40        50        60
pF1KB3 MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SKENLKEKGPQNATDSYVHKQYPANQGQEVEYFVAGTHPYPPGPGVALTADTKIQRMPSE
       ::::::::::::::::::::::::::::::::::::         :::::::::::::::
NP_001 SKENLKEKGPQNATDSYVHKQYPANQGQEVEYFVAG---------VALTADTKIQRMPSE
               70        80        90                100       110 

              130       140       150       160       170       180
pF1KB3 SAAQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAAQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAK
             120       130       140       150       160       170 

              190       200       210       220       230       240
pF1KB3 KAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKL
             180       190       200       210       220       230 

              250       260       270       280       290       300
pF1KB3 SLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTI
             240       250       260       270       280       290 

              310       320       330       340       350       360
pF1KB3 DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV
             300       310       320       330       340       350 

              370       380       390       400       410       420
pF1KB3 AGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLT
             360       370       380       390       400       410 

              430       440       450       460       470       480
pF1KB3 VNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTA
             420       430       440       450       460       470 

              490       500       510    
pF1KB3 EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
       ::::::::::::::::::::::::::::::::::
NP_001 EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
             480       490       500     

>>NP_060058 (OMIM: 609012) WD repeat-containing protein   (334 aa)
 initn: 371 init1: 371 opt: 501  Z-score: 367.7  bits: 77.0 E(85289): 9.7e-14
Smith-Waterman score: 501; 26.7% identity (60.6% similar) in 348 aa overlap (153-492:2-333)

            130       140       150       160       170       180  
pF1KB3 AQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAKKA
                                     :... .: .  . .. : ..  :: ..: .
NP_060                              MATEEKKPETEAARAQPTPSS--SATQSKPT
                                            10        20           

            190       200       210       220       230       240  
pF1KB3 PTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSL
       :. :.      . :  ...::   :  .   :...:....:::. ::::   .::.. ..
NP_060 PVKPN------YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTI
      30              40        50        60        70        80   

            250       260       270       280       290       300  
pF1KB3 TGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDV
       .::   .  :  :. :  : : ..:: .: ::.  .: ..  .:: . :.  ...:  ..
NP_060 SGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNL
            90       100       110       120       130       140   

            310       320       330       340       350       360  
pF1KB3 LVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAG
       .:. : : ..:::::.:   ..:: .:.. :..:. .     :...:.:   :.:: ..:
NP_060 IVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG
           150       160       170       180       190       200   

            370        380        390       400       410          
pF1KB3 KTRVTLTNHKKS-VRAVVLHPR-HYTFASGSPDNIKQWKFPDGSFIQNLSGHNA----II
       .   :: .  .  :  : . :  .: .:.   ...: : .  :. ... .::.     :.
NP_060 QCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIF
           210       220       230       240       250       260   

        420       430       440       450       460       470      
pF1KB3 NTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESR
        ...:..   .:::.... ...:. .:    :...     :  :    ... :   .:. 
NP_060 ANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ-----GHTDV---VISTACHPTENI
           270       280       290            300          310     

        480         490       500       510    
pF1KB3 LLTA--EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
       . .:  : :::::... :                      
NP_060 IASAALENDKTIKLWKSDC                     
         320       330                         

>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta  (334 aa)
 initn: 371 init1: 371 opt: 501  Z-score: 367.7  bits: 77.0 E(85289): 9.7e-14
Smith-Waterman score: 501; 26.7% identity (60.6% similar) in 348 aa overlap (153-492:2-333)

            130       140       150       160       170       180  
pF1KB3 AQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAKKA
                                     :... .: .  . .. : ..  :: ..: .
XP_005                              MATEEKKPETEAARAQPTPSS--SATQSKPT
                                            10        20           

            190       200       210       220       230       240  
pF1KB3 PTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSL
       :. :.      . :  ...::   :  .   :...:....:::. ::::   .::.. ..
XP_005 PVKPN------YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTI
      30              40        50        60        70        80   

            250       260       270       280       290       300  
pF1KB3 TGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDV
       .::   .  :  :. :  : : ..:: .: ::.  .: ..  .:: . :.  ...:  ..
XP_005 SGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNL
            90       100       110       120       130       140   

            310       320       330       340       350       360  
pF1KB3 LVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAG
       .:. : : ..:::::.:   ..:: .:.. :..:. .     :...:.:   :.:: ..:
XP_005 IVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG
           150       160       170       180       190       200   

            370        380        390       400       410          
pF1KB3 KTRVTLTNHKKS-VRAVVLHPR-HYTFASGSPDNIKQWKFPDGSFIQNLSGHNA----II
       .   :: .  .  :  : . :  .: .:.   ...: : .  :. ... .::.     :.
XP_005 QCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIF
           210       220       230       240       250       260   

        420       430       440       450       460       470      
pF1KB3 NTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESR
        ...:..   .:::.... ...:. .:    :...     :  :    ... :   .:. 
XP_005 ANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ-----GHTDV---VISTACHPTENI
           270       280       290            300          310     

        480         490       500       510    
pF1KB3 LLTA--EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
       . .:  : :::::... :                      
XP_005 IASAALENDKTIKLWKSDC                     
         320       330                         

>>NP_438172 (OMIM: 609012) WD repeat-containing protein   (334 aa)
 initn: 371 init1: 371 opt: 501  Z-score: 367.7  bits: 77.0 E(85289): 9.7e-14
Smith-Waterman score: 501; 26.7% identity (60.6% similar) in 348 aa overlap (153-492:2-333)

            130       140       150       160       170       180  
pF1KB3 AQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAKKA
                                     :... .: .  . .. : ..  :: ..: .
NP_438                              MATEEKKPETEAARAQPTPSS--SATQSKPT
                                            10        20           

            190       200       210       220       230       240  
pF1KB3 PTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSL
       :. :.      . :  ...::   :  .   :...:....:::. ::::   .::.. ..
NP_438 PVKPN------YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTI
      30              40        50        60        70        80   

            250       260       270       280       290       300  
pF1KB3 TGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDV
       .::   .  :  :. :  : : ..:: .: ::.  .: ..  .:: . :.  ...:  ..
NP_438 SGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNL
            90       100       110       120       130       140   

            310       320       330       340       350       360  
pF1KB3 LVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAG
       .:. : : ..:::::.:   ..:: .:.. :..:. .     :...:.:   :.:: ..:
NP_438 IVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG
           150       160       170       180       190       200   

            370        380        390       400       410          
pF1KB3 KTRVTLTNHKKS-VRAVVLHPR-HYTFASGSPDNIKQWKFPDGSFIQNLSGHNA----II
       .   :: .  .  :  : . :  .: .:.   ...: : .  :. ... .::.     :.
NP_438 QCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIF
           210       220       230       240       250       260   

        420       430       440       450       460       470      
pF1KB3 NTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESR
        ...:..   .:::.... ...:. .:    :...     :  :    ... :   .:. 
NP_438 ANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ-----GHTDV---VISTACHPTENI
           270       280       290            300          310     

        480         490       500       510    
pF1KB3 LLTA--EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
       . .:  : :::::... :                      
NP_438 IASAALENDKTIKLWKSDC                     
         320       330                         

>>XP_016878353 (OMIM: 602703,616212) PREDICTED: katanin   (655 aa)
 initn: 728 init1: 409 opt: 462  Z-score: 337.5  bits: 72.4 E(85289): 4.6e-12
Smith-Waterman score: 462; 28.5% identity (63.1% similar) in 260 aa overlap (194-450:11-268)

           170       180       190       200       210        220  
pF1KB3 SIVMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAV-EPGNQWFVTG
                                     ::: .... : . :  ... . ... ..::
XP_016                     MATPVVTKTAWKLQEIVA-HASNVSSLVLGKASGRLLATG
                                   10         20        30         

            230       240       250       260       270       280  
pF1KB3 SADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR
       . :  ...:.. . .  .::::: : :..: ..:    . . ... ... ::::  :..:
XP_016 GDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILR
      40        50        60        70        80        90         

            290       300       310       320       330       340  
pF1KB3 HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAE
          :: . . .::.::  . ... :.:.. ..::.: :. :    ::..::  .: .   
XP_016 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDG
     100       110       120       130       140       150         

            350       360       370       380       390        400 
pF1KB3 PQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFP
         . ... : :..::::.:::    . .:   : .: .:: .: .:::: : .:. : . 
XP_016 KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE
     160       170       180       190       200       210         

             410       420        430       440       450       460
pF1KB3 DGSFIQNLSGHNAIINTLTVNSDGV-LVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLD
         . .. . :. . . ..  : ::  : :: .. ..... :.    :. :          
XP_016 KFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPERCFDVVLVNWGKVADL
     220       230       240       250        260       270        

              470       480       490       500       510          
pF1KB3 SESGIFACAFDQSESRLLTAEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF      
                                                                   
XP_016 AICNDQLIGVAFSQSNVSSYVVDLTRVTRTGTVARDPVQDHRPLAQPLPNPSAPLRRIYE
      280       290       300       310       320       330        

>>NP_005877 (OMIM: 602703,616212) katanin p80 WD40 repea  (655 aa)
 initn: 728 init1: 409 opt: 462  Z-score: 337.5  bits: 72.4 E(85289): 4.6e-12
Smith-Waterman score: 462; 28.5% identity (63.1% similar) in 260 aa overlap (194-450:11-268)

           170       180       190       200       210        220  
pF1KB3 SIVMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAV-EPGNQWFVTG
                                     ::: .... : . :  ... . ... ..::
NP_005                     MATPVVTKTAWKLQEIVA-HASNVSSLVLGKASGRLLATG
                                   10         20        30         

            230       240       250       260       270       280  
pF1KB3 SADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR
       . :  ...:.. . .  .::::: : :..: ..:    . . ... ... ::::  :..:
NP_005 GDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILR
      40        50        60        70        80        90         

            290       300       310       320       330       340  
pF1KB3 HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAE
          :: . . .::.::  . ... :.:.. ..::.: :. :    ::..::  .: .   
NP_005 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDG
     100       110       120       130       140       150         

            350       360       370       380       390        400 
pF1KB3 PQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFP
         . ... : :..::::.:::    . .:   : .: .:: .: .:::: : .:. : . 
NP_005 KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE
     160       170       180       190       200       210         

             410       420        430       440       450       460
pF1KB3 DGSFIQNLSGHNAIINTLTVNSDGV-LVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLD
         . .. . :. . . ..  : ::  : :: .. ..... :.    :. :          
NP_005 KFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPERCFDVVLVNWGKVADL
     220       230       240       250        260       270        

              470       480       490       500       510          
pF1KB3 SESGIFACAFDQSESRLLTAEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF      
                                                                   
NP_005 AICNDQLIGVAFSQSNVSSYVVDLTRVTRTGTVARDPVQDHRPLAQPLPNPSAPLRRIYE
      280       290       300       310       320       330        

>>XP_016878352 (OMIM: 602703,616212) PREDICTED: katanin   (655 aa)
 initn: 728 init1: 409 opt: 462  Z-score: 337.5  bits: 72.4 E(85289): 4.6e-12
Smith-Waterman score: 462; 28.5% identity (63.1% similar) in 260 aa overlap (194-450:11-268)

           170       180       190       200       210        220  
pF1KB3 SIVMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAV-EPGNQWFVTG
                                     ::: .... : . :  ... . ... ..::
XP_016                     MATPVVTKTAWKLQEIVA-HASNVSSLVLGKASGRLLATG
                                   10         20        30         

            230       240       250       260       270       280  
pF1KB3 SADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR
       . :  ...:.. . .  .::::: : :..: ..:    . . ... ... ::::  :..:
XP_016 GDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILR
      40        50        60        70        80        90         

            290       300       310       320       330       340  
pF1KB3 HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAE
          :: . . .::.::  . ... :.:.. ..::.: :. :    ::..::  .: .   
XP_016 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDG
     100       110       120       130       140       150         

            350       360       370       380       390        400 
pF1KB3 PQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFP
         . ... : :..::::.:::    . .:   : .: .:: .: .:::: : .:. : . 
XP_016 KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE
     160       170       180       190       200       210         

             410       420        430       440       450       460
pF1KB3 DGSFIQNLSGHNAIINTLTVNSDGV-LVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLD
         . .. . :. . . ..  : ::  : :: .. ..... :.    :. :          
XP_016 KFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPERCFDVVLVNWGKVADL
     220       230       240       250        260       270        

              470       480       490       500       510          
pF1KB3 SESGIFACAFDQSESRLLTAEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF      
                                                                   
XP_016 AICNDQLIGVAFSQSNVSSYVVDLTRVTRTGTVARDPVQDHRPLAQPLPNPSAPLRRIYE
      280       290       300       310       320       330        

>>XP_006721186 (OMIM: 602703,616212) PREDICTED: katanin   (658 aa)
 initn: 728 init1: 409 opt: 462  Z-score: 337.5  bits: 72.4 E(85289): 4.6e-12
Smith-Waterman score: 462; 28.5% identity (63.1% similar) in 260 aa overlap (194-450:11-268)

           170       180       190       200       210        220  
pF1KB3 SIVMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAV-EPGNQWFVTG
                                     ::: .... : . :  ... . ... ..::
XP_006                     MATPVVTKTAWKLQEIVA-HASNVSSLVLGKASGRLLATG
                                   10         20        30         

            230       240       250       260       270       280  
pF1KB3 SADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR
       . :  ...:.. . .  .::::: : :..: ..:    . . ... ... ::::  :..:
XP_006 GDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILR
      40        50        60        70        80        90         

            290       300       310       320       330       340  
pF1KB3 HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAE
          :: . . .::.::  . ... :.:.. ..::.: :. :    ::..::  .: .   
XP_006 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDG
     100       110       120       130       140       150         

            350       360       370       380       390        400 
pF1KB3 PQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFP
         . ... : :..::::.:::    . .:   : .: .:: .: .:::: : .:. : . 
XP_006 KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE
     160       170       180       190       200       210         

             410       420        430       440       450       460
pF1KB3 DGSFIQNLSGHNAIINTLTVNSDGV-LVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLD
         . .. . :. . . ..  : ::  : :: .. ..... :.    :. :          
XP_006 KFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPERCFDVVLVNWGKVADL
     220       230       240       250        260       270        

              470       480       490       500       510          
pF1KB3 SESGIFACAFDQSESRLLTAEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF      
                                                                   
XP_006 AICNDQLIGVAFSQSNVSSYVVDLTRVTRTGTVARDPVQDHRPLAQPLPNPSAPLRRIYE
      280       290       300       310       320       330        

>>XP_016878351 (OMIM: 602703,616212) PREDICTED: katanin   (672 aa)
 initn: 728 init1: 409 opt: 462  Z-score: 337.4  bits: 72.4 E(85289): 4.7e-12
Smith-Waterman score: 462; 28.5% identity (63.1% similar) in 260 aa overlap (194-450:11-268)

           170       180       190       200       210        220  
pF1KB3 SIVMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAV-EPGNQWFVTG
                                     ::: .... : . :  ... . ... ..::
XP_016                     MATPVVTKTAWKLQEIVA-HASNVSSLVLGKASGRLLATG
                                   10         20        30         

            230       240       250       260       270       280  
pF1KB3 SADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR
       . :  ...:.. . .  .::::: : :..: ..:    . . ... ... ::::  :..:
XP_016 GDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILR
      40        50        60        70        80        90         

            290       300       310       320       330       340  
pF1KB3 HYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAE
          :: . . .::.::  . ... :.:.. ..::.: :. :    ::..::  .: .   
XP_016 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDG
     100       110       120       130       140       150         

            350       360       370       380       390        400 
pF1KB3 PQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFP
         . ... : :..::::.:::    . .:   : .: .:: .: .:::: : .:. : . 
XP_016 KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE
     160       170       180       190       200       210         

             410       420        430       440       450       460
pF1KB3 DGSFIQNLSGHNAIINTLTVNSDGV-LVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLD
         . .. . :. . . ..  : ::  : :: .. ..... :.    :. :          
XP_016 KFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPERCFDVVLVNWGKVADL
     220       230       240       250        260       270        

              470       480       490       500       510          
pF1KB3 SESGIFACAFDQSESRLLTAEADKTIKVYREDDTATEETHPVSWKPEIIKRKRF      
                                                                   
XP_016 AICNDQLIGVAFSQSNVSSYVVDLTRVTRTGTVARDPVQDHRPLAQPLPNPSAPLRRIYE
      280       290       300       310       320       330        




514 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 04:55:26 2016 done: Sat Nov  5 04:55:28 2016
 Total Scan time:  9.520 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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