FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3343, 897 aa 1>>>pF1KB3343 897 - 897 aa - 897 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.0304+/-0.000461; mu= -12.8605+/- 0.029 mean_var=585.8986+/-124.245, 0's: 0 Z-trim(123.6): 84 B-trim: 830 in 1/60 Lambda= 0.052986 statistics sampled from 43633 (43742) to 43633 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.513), width: 16 Scan time: 14.290 The best scores are: opt bits E(85289) NP_000386 (OMIM: 138981,614370) cytokine receptor ( 897) 6304 497.5 1.2e-139 XP_005261397 (OMIM: 138981,614370) PREDICTED: cyto ( 903) 6282 495.8 3.8e-139 XP_011528206 (OMIM: 138981,614370) PREDICTED: cyto ( 909) 3248 263.9 2.5e-69 XP_011528205 (OMIM: 138981,614370) PREDICTED: cyto ( 915) 3248 263.9 2.5e-69 XP_011528207 (OMIM: 138981,614370) PREDICTED: cyto ( 529) 3034 247.3 1.4e-64 >>NP_000386 (OMIM: 138981,614370) cytokine receptor comm (897 aa) initn: 6304 init1: 6304 opt: 6304 Z-score: 2628.3 bits: 497.5 E(85289): 1.2e-139 Smith-Waterman score: 6304; 100.0% identity (100.0% similar) in 897 aa overlap (1-897:1-897) 10 20 30 40 50 60 pF1KB3 MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSYSLRWET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 HTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSYSLRWET 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 MKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVRTSRTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVRTSRTG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 YNGIWSEWSEARSWDTESVLPMWVLALIVIFLTIAVLLALRFCGIYGYRLRRKWEEKIPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 YNGIWSEWSEARSWDTESVLPMWVLALIVIFLTIAVLLALRFCGIYGYRLRRKWEEKIPN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 PSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 DPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 SLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 GAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 PNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 RNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPS 790 800 810 820 830 840 850 860 870 880 890 pF1KB3 SPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQDYLSLPPWEVNKPGEVC ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQDYLSLPPWEVNKPGEVC 850 860 870 880 890 >>XP_005261397 (OMIM: 138981,614370) PREDICTED: cytokine (903 aa) initn: 6290 init1: 4308 opt: 6282 Z-score: 2619.2 bits: 495.8 E(85289): 3.8e-139 Smith-Waterman score: 6282; 99.3% identity (99.3% similar) in 903 aa overlap (1-897:1-903) 10 20 30 40 50 60 pF1KB3 MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPG 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 DEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAG------EEECSPVLR ::::::::::::::::::::::::::::::::::::::::::::: ::::::::: XP_005 DEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGSAVLLREEECSPVLR 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 EGLGSLHTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EGLGSLHTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSY 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 SLRWETMKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLRWETMKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRV 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 RTSRTGYNGIWSEWSEARSWDTESVLPMWVLALIVIFLTIAVLLALRFCGIYGYRLRRKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTSRTGYNGIWSEWSEARSWDTESVLPMWVLALIVIFLTIAVLLALRFCGIYGYRLRRKW 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 EEKIPNPSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEKIPNPSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEV 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 SPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYL 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB3 GPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEV 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB3 ERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSS 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB3 ADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEG 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB3 RSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLS 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB3 LRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQDYLSLPPWEVNKPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQDYLSLPPWEVNKPG 850 860 870 880 890 900 pF1KB3 EVC ::: XP_005 EVC >>XP_011528206 (OMIM: 138981,614370) PREDICTED: cytokine (909 aa) initn: 6290 init1: 3248 opt: 3248 Z-score: 1365.7 bits: 263.9 E(85289): 2.5e-69 Smith-Waterman score: 6270; 98.7% identity (98.7% similar) in 909 aa overlap (1-897:1-909) 10 20 30 40 50 60 pF1KB3 MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSYSLRWET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSYSLRWET 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 MKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVRTSRTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVRTSRTG 370 380 390 400 410 420 430 440 450 460 pF1KB3 YNGIWSEWSEARSWDTES------------VLPMWVLALIVIFLTIAVLLALRFCGIYGY :::::::::::::::::: :::::::::::::::::::::::::::::: XP_011 YNGIWSEWSEARSWDTESDADIPLSPRLLEVLPMWVLALIVIFLTIAVLLALRFCGIYGY 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB3 RLRRKWEEKIPNPSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLRRKWEEKIPNPSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVG 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB3 FGDSEVSPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FGDSEVSPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFD 550 560 570 580 590 600 590 600 610 620 630 640 pF1KB3 FNGPYLGPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FNGPYLGPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGP 610 620 630 640 650 660 650 660 670 680 690 700 pF1KB3 GQAVEVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQAVEVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVA 670 680 690 700 710 720 710 720 730 740 750 760 pF1KB3 SGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVE 730 740 750 760 770 780 770 780 790 800 810 820 pF1KB3 LPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGL 790 800 810 820 830 840 830 840 850 860 870 880 pF1KB3 GPGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQDYLSLPPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQDYLSLPPW 850 860 870 880 890 900 890 pF1KB3 EVNKPGEVC ::::::::: XP_011 EVNKPGEVC >>XP_011528205 (OMIM: 138981,614370) PREDICTED: cytokine (915 aa) initn: 6276 init1: 3248 opt: 3248 Z-score: 1365.7 bits: 263.9 E(85289): 2.5e-69 Smith-Waterman score: 6248; 98.0% identity (98.0% similar) in 915 aa overlap (1-897:1-915) 10 20 30 40 50 60 pF1KB3 MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPG 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 DEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAG------EEECSPVLR ::::::::::::::::::::::::::::::::::::::::::::: ::::::::: XP_011 DEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGSAVLLREEECSPVLR 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 EGLGSLHTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGLGSLHTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSY 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 SLRWETMKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLRWETMKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRV 370 380 390 400 410 420 420 430 440 450 460 pF1KB3 RTSRTGYNGIWSEWSEARSWDTES------------VLPMWVLALIVIFLTIAVLLALRF :::::::::::::::::::::::: :::::::::::::::::::::::: XP_011 RTSRTGYNGIWSEWSEARSWDTESDADIPLSPRLLEVLPMWVLALIVIFLTIAVLLALRF 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB3 CGIYGYRLRRKWEEKIPNPSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CGIYGYRLRRKWEEKIPNPSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELE 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB3 GVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEK 550 560 570 580 590 600 590 600 610 620 630 640 pF1KB3 QASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPL 610 620 630 640 650 660 650 660 670 680 690 700 pF1KB3 AQAMGPGQAVEVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQAMGPGQAVEVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDT 670 680 690 700 710 720 710 720 730 740 750 760 pF1KB3 EDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSG 730 740 750 760 770 780 770 780 790 800 810 820 pF1KB3 FEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDY 790 800 810 820 830 840 830 840 850 860 870 880 pF1KB3 CFLPGLGPGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CFLPGLGPGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQDY 850 860 870 880 890 900 890 pF1KB3 LSLPPWEVNKPGEVC ::::::::::::::: XP_011 LSLPPWEVNKPGEVC 910 >>XP_011528207 (OMIM: 138981,614370) PREDICTED: cytokine (529 aa) initn: 3366 init1: 1996 opt: 3034 Z-score: 1280.2 bits: 247.3 E(85289): 1.4e-64 Smith-Waterman score: 3339; 92.7% identity (93.8% similar) in 531 aa overlap (1-513:1-525) 10 20 30 40 50 60 pF1KB3 MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPG 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 DEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAG------EEECSPVLR ::::::::::::::::::::::::::::::::::::::::::::: ::::::::: XP_011 DEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGSAVLLREEECSPVLR 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 EGLGSLHTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGLGSLHTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSY 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB3 SLRWETMKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLRWETMKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRV 370 380 390 400 410 420 420 430 440 450 460 pF1KB3 RTSRTGYNGIWSEWSEARSWDTES------------VLPMWVLALIVIFLTIAVLLALRF :::::::::::::::::::::::: :::::::::::::::::::::::: XP_011 RTSRTGYNGIWSEWSEARSWDTESDADIPLSPRLLEVLPMWVLALIVIFLTIAVLLALRF 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB3 CGIYGYRLRRKWEEKIPNPSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELE ::::::::::::::::::::::::::. : . . . . :.:: XP_011 CGIYGYRLRRKWEEKIPNPSKSHLFQG------VPCRIRGQRGVTSHHRGPQACL 490 500 510 520 530 540 550 560 570 580 pF1KB3 GVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEK 897 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:57:59 2016 done: Thu Nov 3 12:58:01 2016 Total Scan time: 14.290 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]