FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3347, 737 aa 1>>>pF1KB3347 737 - 737 aa - 737 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.1722+/-0.000432; mu= -2.4293+/- 0.027 mean_var=256.9889+/-52.100, 0's: 0 Z-trim(118.3): 24 B-trim: 333 in 2/55 Lambda= 0.080005 statistics sampled from 31153 (31177) to 31153 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.366), width: 16 Scan time: 10.180 The best scores are: opt bits E(85289) NP_002754 (OMIM: 601546) prospero homeobox protein ( 737) 4916 581.3 4.8e-165 NP_001257545 (OMIM: 601546) prospero homeobox prot ( 737) 4916 581.3 4.8e-165 XP_016857322 (OMIM: 601546) PREDICTED: prospero ho ( 737) 4916 581.3 4.8e-165 XP_011508074 (OMIM: 601546) PREDICTED: prospero ho ( 738) 4904 579.9 1.3e-164 XP_011508075 (OMIM: 601546) PREDICTED: prospero ho ( 738) 4904 579.9 1.3e-164 XP_005273251 (OMIM: 601546) PREDICTED: prospero ho ( 738) 4904 579.9 1.3e-164 XP_005273252 (OMIM: 601546) PREDICTED: prospero ho ( 738) 4904 579.9 1.3e-164 XP_011508073 (OMIM: 601546) PREDICTED: prospero ho ( 738) 4904 579.9 1.3e-164 XP_016857321 (OMIM: 601546) PREDICTED: prospero ho ( 738) 4904 579.9 1.3e-164 NP_001229936 (OMIM: 615094) prospero homeobox prot ( 592) 835 110.2 2.5e-23 XP_005267600 (OMIM: 615094) PREDICTED: prospero ho ( 592) 834 110.1 2.7e-23 NP_001073877 (OMIM: 615094) prospero homeobox prot ( 365) 607 83.7 1.4e-15 XP_016876711 (OMIM: 615094) PREDICTED: prospero ho ( 441) 268 44.7 0.001 >>NP_002754 (OMIM: 601546) prospero homeobox protein 1 [ (737 aa) initn: 4916 init1: 4916 opt: 4916 Z-score: 3084.0 bits: 581.3 E(85289): 4.8e-165 Smith-Waterman score: 4916; 100.0% identity (100.0% similar) in 737 aa overlap (1-737:1-737) 10 20 30 40 50 60 pF1KB3 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 LYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSE 670 680 690 700 710 720 730 pF1KB3 VPEIFKSPNCLQELLHE ::::::::::::::::: NP_002 VPEIFKSPNCLQELLHE 730 >>NP_001257545 (OMIM: 601546) prospero homeobox protein (737 aa) initn: 4916 init1: 4916 opt: 4916 Z-score: 3084.0 bits: 581.3 E(85289): 4.8e-165 Smith-Waterman score: 4916; 100.0% identity (100.0% similar) in 737 aa overlap (1-737:1-737) 10 20 30 40 50 60 pF1KB3 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 LYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSE 670 680 690 700 710 720 730 pF1KB3 VPEIFKSPNCLQELLHE ::::::::::::::::: NP_001 VPEIFKSPNCLQELLHE 730 >>XP_016857322 (OMIM: 601546) PREDICTED: prospero homeob (737 aa) initn: 4916 init1: 4916 opt: 4916 Z-score: 3084.0 bits: 581.3 E(85289): 4.8e-165 Smith-Waterman score: 4916; 100.0% identity (100.0% similar) in 737 aa overlap (1-737:1-737) 10 20 30 40 50 60 pF1KB3 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 LYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSE 670 680 690 700 710 720 730 pF1KB3 VPEIFKSPNCLQELLHE ::::::::::::::::: XP_016 VPEIFKSPNCLQELLHE 730 >>XP_011508074 (OMIM: 601546) PREDICTED: prospero homeob (738 aa) initn: 4508 init1: 4508 opt: 4904 Z-score: 3076.6 bits: 579.9 E(85289): 1.3e-164 Smith-Waterman score: 4904; 99.9% identity (99.9% similar) in 738 aa overlap (1-737:1-738) 10 20 30 40 50 60 pF1KB3 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 LYRALNMHYNKANDFE-VPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDS :::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::: XP_011 LYRALNMHYNKANDFEQVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDS 670 680 690 700 710 720 720 730 pF1KB3 EVPEIFKSPNCLQELLHE :::::::::::::::::: XP_011 EVPEIFKSPNCLQELLHE 730 >>XP_011508075 (OMIM: 601546) PREDICTED: prospero homeob (738 aa) initn: 4508 init1: 4508 opt: 4904 Z-score: 3076.6 bits: 579.9 E(85289): 1.3e-164 Smith-Waterman score: 4904; 99.9% identity (99.9% similar) in 738 aa overlap (1-737:1-738) 10 20 30 40 50 60 pF1KB3 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 LYRALNMHYNKANDFE-VPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDS :::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::: XP_011 LYRALNMHYNKANDFEQVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDS 670 680 690 700 710 720 720 730 pF1KB3 EVPEIFKSPNCLQELLHE :::::::::::::::::: XP_011 EVPEIFKSPNCLQELLHE 730 >>XP_005273251 (OMIM: 601546) PREDICTED: prospero homeob (738 aa) initn: 4508 init1: 4508 opt: 4904 Z-score: 3076.6 bits: 579.9 E(85289): 1.3e-164 Smith-Waterman score: 4904; 99.9% identity (99.9% similar) in 738 aa overlap (1-737:1-738) 10 20 30 40 50 60 pF1KB3 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 LYRALNMHYNKANDFE-VPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDS :::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::: XP_005 LYRALNMHYNKANDFEQVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDS 670 680 690 700 710 720 720 730 pF1KB3 EVPEIFKSPNCLQELLHE :::::::::::::::::: XP_005 EVPEIFKSPNCLQELLHE 730 >>XP_005273252 (OMIM: 601546) PREDICTED: prospero homeob (738 aa) initn: 4508 init1: 4508 opt: 4904 Z-score: 3076.6 bits: 579.9 E(85289): 1.3e-164 Smith-Waterman score: 4904; 99.9% identity (99.9% similar) in 738 aa overlap (1-737:1-738) 10 20 30 40 50 60 pF1KB3 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 LYRALNMHYNKANDFE-VPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDS :::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::: XP_005 LYRALNMHYNKANDFEQVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDS 670 680 690 700 710 720 720 730 pF1KB3 EVPEIFKSPNCLQELLHE :::::::::::::::::: XP_005 EVPEIFKSPNCLQELLHE 730 >>XP_011508073 (OMIM: 601546) PREDICTED: prospero homeob (738 aa) initn: 4508 init1: 4508 opt: 4904 Z-score: 3076.6 bits: 579.9 E(85289): 1.3e-164 Smith-Waterman score: 4904; 99.9% identity (99.9% similar) in 738 aa overlap (1-737:1-738) 10 20 30 40 50 60 pF1KB3 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 LYRALNMHYNKANDFE-VPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDS :::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::: XP_011 LYRALNMHYNKANDFEQVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDS 670 680 690 700 710 720 720 730 pF1KB3 EVPEIFKSPNCLQELLHE :::::::::::::::::: XP_011 EVPEIFKSPNCLQELLHE 730 >>XP_016857321 (OMIM: 601546) PREDICTED: prospero homeob (738 aa) initn: 4508 init1: 4508 opt: 4904 Z-score: 3076.6 bits: 579.9 E(85289): 1.3e-164 Smith-Waterman score: 4904; 99.9% identity (99.9% similar) in 738 aa overlap (1-737:1-738) 10 20 30 40 50 60 pF1KB3 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCE 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 LYRALNMHYNKANDFE-VPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDS :::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::: XP_016 LYRALNMHYNKANDFEQVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDS 670 680 690 700 710 720 720 730 pF1KB3 EVPEIFKSPNCLQELLHE :::::::::::::::::: XP_016 EVPEIFKSPNCLQELLHE 730 >>NP_001229936 (OMIM: 615094) prospero homeobox protein (592 aa) initn: 1077 init1: 798 opt: 835 Z-score: 539.7 bits: 110.2 E(85289): 2.5e-23 Smith-Waterman score: 1094; 37.7% identity (59.9% similar) in 626 aa overlap (124-727:17-587) 100 110 120 130 140 pF1KB3 SQLLKNNMNKNGGTEPSFQASGLSSTGSEVHQEDICSNSSRDSPPECL---SPFGR---P : . :... :.: : : ::: : NP_001 MDPNSILLSPQPQICSHLAEACTEGERSSSPPELDRDSPFPWSQVP 10 20 30 40 150 160 170 180 190 200 pF1KB3 TMSQFDMDRLCDEHLRAKRARVENIIRGMSHSPSVALRGNENEREMAPQSVSPR--ESYR . : : . . :::..:::::::.:.::: ::. . :: : .:::: .. : NP_001 SSSPTDPEWFGDEHIQAKRARVETIVRGMCLSPNPLVPGN------AQAGVSPRCPKKAR 50 60 70 80 90 100 210 220 230 240 250 260 pF1KB3 ENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLKQQLEDMQKQLRQLQEKFYQIYDSTD : ::::.:: : .. . . : . .:. ....::. ...:::.:::.. : : NP_001 ERKRKQNLPTPQ--GLLMPAPAWDQGNRKGGPRVREQLHLLKQQLRHLQEHILQAAKPRD 110 120 130 140 150 270 280 290 300 310 320 pF1KB3 SENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMCELDPGQFIDRARALIREQEMAENKP . . : . . :.:. .. : : : . . . .. NP_001 TAQGPGGCGTGKGP----LSAKQGNGCG----------P-------RPWVVDGDHQQGTS 160 170 180 190 330 340 350 360 370 380 pF1KB3 KR-EGNNKERDHGPNSLQPEGKHLA-ETLKQELNTAMSQVVDTVV-KVFSAKPSR--QVP : : .:... :. : : . : :..::. :.::.::.:. ::. :.. :. NP_001 KDLSGAEKHQESEKPSFLPSGAPASLEILRKELTRAVSQAVDSVLQKVLLDPPGHLTQLG 200 210 220 230 240 250 390 400 410 420 430 pF1KB3 QVFPPLQIPQARFA----VNGENHN---FHTANQRLQCFGDVIIPNPLDTFGNVQMASST . : :. ..: :.: .. . . .:.: . : :. ::...:. NP_001 RSFQG-QVAEGRSEPSPPVGGACKDPLALAALPRRVQLQAGV----PV---GNLSLAKRL 260 270 280 290 300 440 450 460 470 480 490 pF1KB3 DQTE--ALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTFRHPFPLPLMAY :. . : .. : .: :. : .. : .: :: : .. . : . NP_001 DSPRYPIPPRMTPKPCQDPPANFPLTAPSHIQENQI-LSQLLGHRYNNGHWSSSPPQDSS 310 320 330 340 350 360 500 510 520 530 540 550 pF1KB3 PFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSPAHPPSTAEGLS . : . : .. ..:. : :... : ..: :: : :. NP_001 SQRHPSSEP--ALRPWRTTKPQPLVLSQQQCPL--PFTSAHLESLPLLPS---------- 370 380 390 400 410 560 570 580 590 600 610 pF1KB3 LSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSSNMLKTYFSDVK .: : :. . : :.: .::::.:.::::::::::.:::::::.::.:: ::. NP_001 ---VKMEQRGLHAVMEALPFSLVHIQEGLNPGHLKKAKLMFFFTRYPSSNLLKVYFPDVQ 420 430 440 450 460 470 620 630 640 650 660 670 pF1KB3 FNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCELYRALNMHYNK ::::::::.::::::::::::::::: :::::.::::. . : . :. ::..:::::::: NP_001 FNRCITSQMIKWFSNFREFYYIQMEKSARQAISDGVTNPKMLVVLRNSELFQALNMHYNK 480 490 500 510 520 530 680 690 700 710 720 730 pF1KB3 ANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSEVPEIFKSPNCL .::::::. :::.:..::.::: :. ::.: :::::: :::.: ::::..:::::: NP_001 GNDFEVPDCFLEIASLTLQEFFRAVSAGRDSDPSWKKPIYKIISKLDSDIPEIFKSSSYP 540 550 560 570 580 590 pF1KB3 QELLHE NP_001 Q 737 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:56:38 2016 done: Thu Nov 3 20:56:40 2016 Total Scan time: 10.180 Total Display time: 0.200 Function used was FASTA [36.3.4 Apr, 2011]