Result of FASTA (omim) for pF1KB3350
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3350, 635 aa
  1>>>pF1KB3350 635 - 635 aa - 635 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.6346+/-0.000774; mu= -3.9742+/- 0.046
 mean_var=940.0431+/-217.425, 0's: 0 Z-trim(113.9): 1148  B-trim: 0 in 0/52
 Lambda= 0.041831
 statistics sampled from 22202 (23519) to 22202 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.276), width:  16
 Scan time:  9.830

The best scores are:                                      opt bits E(85289)
XP_011517248 (OMIM: 600085) PREDICTED: tyrosine-pr ( 635) 4320 278.1 6.5e-74
XP_005252204 (OMIM: 600085) PREDICTED: tyrosine-pr ( 635) 4320 278.1 6.5e-74
NP_003168 (OMIM: 600085) tyrosine-protein kinase S ( 635) 4320 278.1 6.5e-74
NP_001167638 (OMIM: 600085) tyrosine-protein kinas ( 635) 4320 278.1 6.5e-74
NP_001128524 (OMIM: 600085) tyrosine-protein kinas ( 612) 2258 153.7 1.8e-36
NP_001167639 (OMIM: 600085) tyrosine-protein kinas ( 612) 2258 153.7 1.8e-36
NP_997402 (OMIM: 176947,269840,617006) tyrosine-pr ( 312) 1286 94.5 6.2e-19
NP_001070 (OMIM: 176947,269840,617006) tyrosine-pr ( 619) 1094 83.4 2.6e-15
XP_016860359 (OMIM: 176947,269840,617006) PREDICTE ( 707) 1094 83.5 2.8e-15
XP_016860358 (OMIM: 176947,269840,617006) PREDICTE ( 730) 1094 83.5 2.8e-15
XP_016860356 (OMIM: 176947,269840,617006) PREDICTE ( 742) 1094 83.6 2.8e-15
XP_016860357 (OMIM: 176947,269840,617006) PREDICTE ( 736) 1092 83.4 3.1e-15
XP_016869170 (OMIM: 600758) PREDICTED: focal adhes ( 980)  738 62.3 9.4e-09
XP_006716673 (OMIM: 600758) PREDICTED: focal adhes ( 983)  738 62.3 9.4e-09
XP_006716672 (OMIM: 600758) PREDICTED: focal adhes ( 983)  738 62.3 9.4e-09
XP_005251070 (OMIM: 600758) PREDICTED: focal adhes ( 983)  738 62.3 9.4e-09
XP_016869169 (OMIM: 600758) PREDICTED: focal adhes ( 995)  738 62.3 9.4e-09
XP_016869141 (OMIM: 600758) PREDICTED: focal adhes (1075)  738 62.4 9.8e-09
XP_016869140 (OMIM: 600758) PREDICTED: focal adhes (1093)  738 62.4 9.8e-09
XP_006716671 (OMIM: 600758) PREDICTED: focal adhes (1096)  738 62.4 9.9e-09
XP_005251069 (OMIM: 600758) PREDICTED: focal adhes (1096)  738 62.4 9.9e-09
XP_011515496 (OMIM: 600758) PREDICTED: focal adhes (1096)  738 62.4 9.9e-09
XP_005251060 (OMIM: 600758) PREDICTED: focal adhes (1140)  738 62.4   1e-08
XP_016869179 (OMIM: 600758) PREDICTED: focal adhes ( 913)  730 61.8 1.3e-08
XP_016869178 (OMIM: 600758) PREDICTED: focal adhes ( 919)  730 61.8 1.3e-08
XP_016869177 (OMIM: 600758) PREDICTED: focal adhes ( 919)  730 61.8 1.3e-08
XP_016869176 (OMIM: 600758) PREDICTED: focal adhes ( 934)  730 61.8 1.3e-08
XP_016869173 (OMIM: 600758) PREDICTED: focal adhes ( 949)  730 61.8 1.3e-08
XP_016869172 (OMIM: 600758) PREDICTED: focal adhes ( 955)  730 61.8 1.3e-08
NP_001303271 (OMIM: 600758) focal adhesion kinase  ( 955)  730 61.8 1.3e-08
XP_016869168 (OMIM: 600758) PREDICTED: focal adhes (1011)  730 61.8 1.3e-08
XP_016869166 (OMIM: 600758) PREDICTED: focal adhes (1032)  730 61.9 1.3e-08
XP_016869164 (OMIM: 600758) PREDICTED: focal adhes (1047)  730 61.9 1.3e-08
XP_016869163 (OMIM: 600758) PREDICTED: focal adhes (1047)  730 61.9 1.3e-08
XP_016869158 (OMIM: 600758) PREDICTED: focal adhes (1059)  730 61.9 1.4e-08
XP_016869156 (OMIM: 600758) PREDICTED: focal adhes (1060)  730 61.9 1.4e-08
XP_016869157 (OMIM: 600758) PREDICTED: focal adhes (1060)  730 61.9 1.4e-08
XP_016869151 (OMIM: 600758) PREDICTED: focal adhes (1062)  730 61.9 1.4e-08
XP_016869152 (OMIM: 600758) PREDICTED: focal adhes (1062)  730 61.9 1.4e-08
XP_016869149 (OMIM: 600758) PREDICTED: focal adhes (1068)  730 61.9 1.4e-08
XP_016869150 (OMIM: 600758) PREDICTED: focal adhes (1068)  730 61.9 1.4e-08
XP_016869145 (OMIM: 600758) PREDICTED: focal adhes (1103)  730 61.9 1.4e-08
XP_016869144 (OMIM: 600758) PREDICTED: focal adhes (1104)  730 61.9 1.4e-08
XP_016869143 (OMIM: 600758) PREDICTED: focal adhes (1106)  730 61.9 1.4e-08
XP_016869142 (OMIM: 600758) PREDICTED: focal adhes (1112)  730 61.9 1.4e-08
XP_016869175 (OMIM: 600758) PREDICTED: focal adhes ( 942)  724 61.4 1.7e-08
XP_016869167 (OMIM: 600758) PREDICTED: focal adhes (1016)  724 61.5 1.7e-08
XP_016869148 (OMIM: 600758) PREDICTED: focal adhes (1031)  724 61.5 1.7e-08
XP_016869165 (OMIM: 600758) PREDICTED: focal adhes (1034)  724 61.5 1.7e-08
XP_016869174 (OMIM: 600758) PREDICTED: focal adhes ( 948)  723 61.4 1.7e-08


>>XP_011517248 (OMIM: 600085) PREDICTED: tyrosine-protei  (635 aa)
 initn: 4320 init1: 4320 opt: 4320  Z-score: 1448.0  bits: 278.1 E(85289): 6.5e-74
Smith-Waterman score: 4320; 100.0% identity (100.0% similar) in 635 aa overlap (1-635:1-635)

               10        20        30        40        50        60
pF1KB3 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 PGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
              550       560       570       580       590       600

              610       620       630     
pF1KB3 MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
       :::::::::::::::::::::::::::::::::::
XP_011 MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
              610       620       630     

>>XP_005252204 (OMIM: 600085) PREDICTED: tyrosine-protei  (635 aa)
 initn: 4320 init1: 4320 opt: 4320  Z-score: 1448.0  bits: 278.1 E(85289): 6.5e-74
Smith-Waterman score: 4320; 100.0% identity (100.0% similar) in 635 aa overlap (1-635:1-635)

               10        20        30        40        50        60
pF1KB3 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 PGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
              550       560       570       580       590       600

              610       620       630     
pF1KB3 MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
       :::::::::::::::::::::::::::::::::::
XP_005 MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
              610       620       630     

>>NP_003168 (OMIM: 600085) tyrosine-protein kinase SYK i  (635 aa)
 initn: 4320 init1: 4320 opt: 4320  Z-score: 1448.0  bits: 278.1 E(85289): 6.5e-74
Smith-Waterman score: 4320; 100.0% identity (100.0% similar) in 635 aa overlap (1-635:1-635)

               10        20        30        40        50        60
pF1KB3 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 PGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
              550       560       570       580       590       600

              610       620       630     
pF1KB3 MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
       :::::::::::::::::::::::::::::::::::
NP_003 MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
              610       620       630     

>>NP_001167638 (OMIM: 600085) tyrosine-protein kinase SY  (635 aa)
 initn: 4320 init1: 4320 opt: 4320  Z-score: 1448.0  bits: 278.1 E(85289): 6.5e-74
Smith-Waterman score: 4320; 100.0% identity (100.0% similar) in 635 aa overlap (1-635:1-635)

               10        20        30        40        50        60
pF1KB3 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 PGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
              550       560       570       580       590       600

              610       620       630     
pF1KB3 MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
       :::::::::::::::::::::::::::::::::::
NP_001 MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
              610       620       630     

>>NP_001128524 (OMIM: 600085) tyrosine-protein kinase SY  (612 aa)
 initn: 2334 init1: 2252 opt: 2258  Z-score: 775.5  bits: 153.7 E(85289): 1.8e-36
Smith-Waterman score: 4102; 96.4% identity (96.4% similar) in 635 aa overlap (1-635:1-612)

               10        20        30        40        50        60
pF1KB3 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
       ::::::::::::::::::::::::::::::::::::::::::                  
NP_001 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPA------------------
              250       260       270       280                    

              310       320       330       340       350       360
pF1KB3 PGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRP
            :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -----SSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRP
                 290       300       310       320       330       

              370       380       390       400       410       420
pF1KB3 KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
       340       350       360       370       380       390       

              430       440       450       460       470       480
pF1KB3 ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
       400       410       420       430       440       450       

              490       500       510       520       530       540
pF1KB3 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
       460       470       480       490       500       510       

              550       560       570       580       590       600
pF1KB3 PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
       520       530       540       550       560       570       

              610       620       630     
pF1KB3 MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
       :::::::::::::::::::::::::::::::::::
NP_001 MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
       580       590       600       610  

>>NP_001167639 (OMIM: 600085) tyrosine-protein kinase SY  (612 aa)
 initn: 2334 init1: 2252 opt: 2258  Z-score: 775.5  bits: 153.7 E(85289): 1.8e-36
Smith-Waterman score: 4102; 96.4% identity (96.4% similar) in 635 aa overlap (1-635:1-612)

               10        20        30        40        50        60
pF1KB3 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
       ::::::::::::::::::::::::::::::::::::::::::                  
NP_001 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPA------------------
              250       260       270       280                    

              310       320       330       340       350       360
pF1KB3 PGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRP
            :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -----SSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRP
                 290       300       310       320       330       

              370       380       390       400       410       420
pF1KB3 KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
       340       350       360       370       380       390       

              430       440       450       460       470       480
pF1KB3 ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
       400       410       420       430       440       450       

              490       500       510       520       530       540
pF1KB3 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
       460       470       480       490       500       510       

              550       560       570       580       590       600
pF1KB3 PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
       520       530       540       550       560       570       

              610       620       630     
pF1KB3 MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
       :::::::::::::::::::::::::::::::::::
NP_001 MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
       580       590       600       610  

>>NP_997402 (OMIM: 176947,269840,617006) tyrosine-protei  (312 aa)
 initn: 1219 init1: 1029 opt: 1286  Z-score: 460.9  bits: 94.5 E(85289): 6.2e-19
Smith-Waterman score: 1286; 61.8% identity (83.1% similar) in 296 aa overlap (341-635:1-295)

              320       330       340       350       360       370
pF1KB3 GNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLL
                                     .:::: ::::::.::::.. :...: :  :
NP_997                               MPMDTSVYESPYSDPEELKDKKLFLKRDNL
                                             10        20        30

              380       390       400       410       420       430
pF1KB3 TLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNP
        . : ::: ::::.:..: :.:.:    ::.:.:: .... :  .:.. ::..:.:::::
NP_997 LIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLK-QGTEKADTEEMMREAQIMHQLDNP
               40        50        60         70        80         

              440       450       460        470       480         
pF1KB3 YIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRH-VKDKNIIELVHQVSMGMKYLEESN
       ::::.::.:.::. :::::::  :::.:.:  .:. .  .:. ::.::::::::::::.:
NP_997 YIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKN
      90       100       110       120       130       140         

     490       500       510       520       530       540         
pF1KB3 FVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKF
       ::::::::::::::..:::::::::::::: ::..:: :.. ::::.:::::::::. ::
NP_997 FVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKF
     150       160       170       180       190       200         

     550       560       570       580       590       600         
pF1KB3 SSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCW
       ::.:::::.:: ::::.:::::::. ::: :: :..:.:.:: ::  :: :.: ::. ::
NP_997 SSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCW
     210       220       230       240       250       260         

     610       620       630                      
pF1KB3 TYDVENRPGFAAVELRLRNYYYDVVN                 
        :  :.:: : .:: :.:  ::....                 
NP_997 IYKWEDRPDFLTVEQRMRACYYSLASKVEGPPGSTQKAEAACA
     270       280       290       300       310  

>>NP_001070 (OMIM: 176947,269840,617006) tyrosine-protei  (619 aa)
 initn: 2251 init1: 1046 opt: 1094  Z-score: 395.9  bits: 83.4 E(85289): 2.6e-15
Smith-Waterman score: 2324; 54.4% identity (77.7% similar) in 631 aa overlap (6-635:1-602)

               10        20        30        40        50        60
pF1KB3 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
            : : : :::::.:.:.: :::..:  .::.:::.::::    :::..::..:  .
NP_001      MPDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVR
                    10        20        30        40        50     

               70        80        90       100       110       120
pF1KB3 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
        ::. :::.::::::::::..: .::.::...:.. ::: : :.:: :::.:..:. : :
NP_001 FHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVF
          60        70        80        90       100       110     

              130       140       150       160       170       180
pF1KB3 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
       . :.. ..:.::.:::.:.:.::::::::: ::.::::::::::.:::.:....:::.:.
NP_001 DCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAER
         120       130       140       150       160       170     

              190       200       210       220       230       240
pF1KB3 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
        .  :..:.::::.: : ..:.::: :..   : :: :..::.::  :::: ::::::::
NP_001 KLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQL
         180       190       200       210       220       230     

              250       260       270       280       290       300
pF1KB3 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
       ::. . :::::.  :   : . .. .:.. .. : :: .::.:             . :.
NP_001 VEYLKLKADGLIYCLKEACPN-SSASNASGAAAPTLP-AHPST------------LTHPQ
         240       250        260       270                    280 

              310       320       330       340       350       360
pF1KB3 PGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRP
                   :. .:.. . : :: :  ..   :.   .:::: ::::::.::::.. 
NP_001 ------------RRIDTLNSDGYTPEPARITSPDKPR--PMPMDTSVYESPYSDPEELKD
                         290       300         310       320       

              370       380       390       400       410       420
pF1KB3 KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
       :...: :  : . : ::: ::::.:..: :.:.:    ::.:.:: .... :  .:.. :
NP_001 KKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLK-QGTEKADTEEMMRE
       330       340       350       360       370        380      

              430       440       450       460        470         
pF1KB3 ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRH-VKDKNIIELVHQVS
       :..:.:::::::::.::.:.::. :::::::  :::.:.:  .:. .  .:. ::.::::
NP_001 AQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVS
        390       400       410       420       430       440      

     480       490       500       510       520       530         
pF1KB3 MGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWY
       ::::::::.:::::::::::::::..:::::::::::::: ::..:: :.. ::::.:::
NP_001 MGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWY
        450       460       470       480       490       500      

     540       550       560       570       580       590         
pF1KB3 APECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPR
       ::::::. ::::.:::::.:: ::::.:::::::. ::: :: :..:.:.:: ::  :: 
NP_001 APECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPP
        510       520       530       540       550       560      

     600       610       620       630                      
pF1KB3 EMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN                 
       :.: ::. :: :  :.:: : .:: :.:  ::....                 
NP_001 ELYALMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVEGPPGSTQKAEAACA
        570       580       590       600       610         

>>XP_016860359 (OMIM: 176947,269840,617006) PREDICTED: t  (707 aa)
 initn: 2187 init1: 1046 opt: 1094  Z-score: 395.4  bits: 83.5 E(85289): 2.8e-15
Smith-Waterman score: 2260; 54.8% identity (78.0% similar) in 608 aa overlap (6-612:124-702)

                                        10        20        30     
pF1KB3                          MASSGMADSANHLPFFFGNITREEAEDYLVQGGMS
                                     : : : :::::.:.:.: :::..:  .::.
XP_016 WREAGKCVPGRKHPRQEGTGVHEVSGGPGAMPDPAAHLPFFYGSISRAEAEEHLKLAGMA
           100       110       120       130       140       150   

          40        50        60        70        80        90     
pF1KB3 DGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTYAIAGGRTHASPADLCHYHSQE
       :::.::::    :::..::..:  . ::. :::.::::::::::..: .::.::...:..
XP_016 DGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRD
           160       170       180       190       200       210   

         100       110       120       130       140       150     
pF1KB3 SDGLVCLLKKPFNRPQGVQPKTGPFEDLKENLIREYVKQTWNLQGQALEQAIISQKPQLE
        ::: : :.:: :::.:..:. : :. :.. ..:.::.:::.:.:.::::::::: ::.:
XP_016 PDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVE
           220       230       240       250       260       270   

         160       170       180       190       200       210     
pF1KB3 KLIATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLH
       :::::::::.:::.:....:::.:. .  :..:.::::.: : ..:.::: :..   : :
XP_016 KLIATTAHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYH
           280       290       300       310       320       330   

         220       230       240       250       260       270     
pF1KB3 YRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQ
       : :..::.::  :::: ::::::::::. . :::::.  :   : . .. .:.. .. : 
XP_016 YLISQDKAGKYCIPEGTKFDTLWQLVEYLKLKADGLIYCLKEACPN-SSASNASGAAAPT
           340       350       360       370        380       390  

         280       290       300       310       320       330     
pF1KB3 LPGSHPATWSAGGIISRIKSYSFPKPGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKG
       :: .::.:             . :.            :. .:.. . : :: :  ..   
XP_016 LP-AHPST------------LTHPQ------------RRIDTLNSDGYTPEPARITSPDK
                         400                   410       420       

         340       350       360       370       380       390     
pF1KB3 PQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKV
       :.   .:::: ::::::.::::.. :...: :  : . : ::: ::::.:..: :.:.: 
XP_016 PR--PMPMDTSVYESPYSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKK
         430       440       450       460       470       480     

         400       410       420       430       440       450     
pF1KB3 VKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGP
          ::.:.:: .... :  .:.. ::..:.:::::::::.::.:.::. :::::::  ::
XP_016 QIDVAIKVLK-QGTEKADTEEMMREAQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGGP
         490        500       510       520       530       540    

         460        470       480       490       500       510    
pF1KB3 LNKYLQQNRH-VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFG
       :.:.:  .:. .  .:. ::.::::::::::::.:::::::::::::::..:::::::::
XP_016 LHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFG
          550       560       570       580       590       600    

          520       530       540       550       560       570    
pF1KB3 LSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYR
       ::::: ::..:: :.. ::::.:::::::::. ::::.:::::.:: ::::.:::::::.
XP_016 LSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYK
          610       620       630       640       650       660    

          580       590       600       610       620       630    
pF1KB3 GMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVV
        ::: :: :..:.:.:: ::  :: :.: ::. :: :.                      
XP_016 KMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYNPSPSS                 
          670       680       690       700                        

        
pF1KB3 N

>>XP_016860358 (OMIM: 176947,269840,617006) PREDICTED: t  (730 aa)
 initn: 2189 init1: 1046 opt: 1094  Z-score: 395.3  bits: 83.5 E(85289): 2.8e-15
Smith-Waterman score: 2262; 54.8% identity (77.8% similar) in 609 aa overlap (6-613:124-703)

                                        10        20        30     
pF1KB3                          MASSGMADSANHLPFFFGNITREEAEDYLVQGGMS
                                     : : : :::::.:.:.: :::..:  .::.
XP_016 WREAGKCVPGRKHPRQEGTGVHEVSGGPGAMPDPAAHLPFFYGSISRAEAEEHLKLAGMA
           100       110       120       130       140       150   

          40        50        60        70        80        90     
pF1KB3 DGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTYAIAGGRTHASPADLCHYHSQE
       :::.::::    :::..::..:  . ::. :::.::::::::::..: .::.::...:..
XP_016 DGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRD
           160       170       180       190       200       210   

         100       110       120       130       140       150     
pF1KB3 SDGLVCLLKKPFNRPQGVQPKTGPFEDLKENLIREYVKQTWNLQGQALEQAIISQKPQLE
        ::: : :.:: :::.:..:. : :. :.. ..:.::.:::.:.:.::::::::: ::.:
XP_016 PDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVE
           220       230       240       250       260       270   

         160       170       180       190       200       210     
pF1KB3 KLIATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLH
       :::::::::.:::.:....:::.:. .  :..:.::::.: : ..:.::: :..   : :
XP_016 KLIATTAHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYH
           280       290       300       310       320       330   

         220       230       240       250       260       270     
pF1KB3 YRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQ
       : :..::.::  :::: ::::::::::. . :::::.  :   : . .. .:.. .. : 
XP_016 YLISQDKAGKYCIPEGTKFDTLWQLVEYLKLKADGLIYCLKEACPN-SSASNASGAAAPT
           340       350       360       370        380       390  

         280       290       300       310       320       330     
pF1KB3 LPGSHPATWSAGGIISRIKSYSFPKPGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKG
       :: .::.:             . :.            :. .:.. . : :: :  ..   
XP_016 LP-AHPST------------LTHPQ------------RRIDTLNSDGYTPEPARITSPDK
                         400                   410       420       

         340       350       360       370       380       390     
pF1KB3 PQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKV
       :.   .:::: ::::::.::::.. :...: :  : . : ::: ::::.:..: :.:.: 
XP_016 PR--PMPMDTSVYESPYSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKK
         430       440       450       460       470       480     

         400       410       420       430       440       450     
pF1KB3 VKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGP
          ::.:.:: .... :  .:.. ::..:.:::::::::.::.:.::. :::::::  ::
XP_016 QIDVAIKVLK-QGTEKADTEEMMREAQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGGP
         490        500       510       520       530       540    

         460        470       480       490       500       510    
pF1KB3 LNKYLQQNRH-VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFG
       :.:.:  .:. .  .:. ::.::::::::::::.:::::::::::::::..:::::::::
XP_016 LHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFG
          550       560       570       580       590       600    

          520       530       540       550       560       570    
pF1KB3 LSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYR
       ::::: ::..:: :.. ::::.:::::::::. ::::.:::::.:: ::::.:::::::.
XP_016 LSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYK
          610       620       630       640       650       660    

          580       590       600       610       620       630    
pF1KB3 GMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVV
        ::: :: :..:.:.:: ::  :: :.: ::. :: : :                     
XP_016 KMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKVSSAHADSPLGLCIHRCRCLES
          670       680       690       700       710       720    

             
pF1KB3 N     
             
XP_016 SPRPHR
          730




635 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 13:00:45 2016 done: Thu Nov  3 13:00:47 2016
 Total Scan time:  9.830 Total Display time:  0.130

Function used was FASTA [36.3.4 Apr, 2011]
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