Result of FASTA (ccds) for pF1KB3372
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3372, 445 aa
  1>>>pF1KB3372 445 - 445 aa - 445 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.8834+/-0.000969; mu= 10.1974+/- 0.058
 mean_var=96.9947+/-19.395, 0's: 0 Z-trim(106.8): 20  B-trim: 0 in 0/51
 Lambda= 0.130227
 statistics sampled from 9169 (9177) to 9169 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.282), width:  16
 Scan time:  2.270

The best scores are:                                      opt bits E(32554)
CCDS7643.1 CTBP2 gene_id:1488|Hs108|chr10          ( 445) 2973 569.0 3.3e-162
CCDS7644.1 CTBP2 gene_id:1488|Hs108|chr10          ( 985) 2837 543.6 3.3e-154
CCDS43203.1 CTBP1 gene_id:1487|Hs108|chr4          ( 429) 2417 464.5 8.9e-131
CCDS3348.1 CTBP1 gene_id:1487|Hs108|chr4           ( 440) 2417 464.6 9.1e-131
CCDS904.1 PHGDH gene_id:26227|Hs108|chr1           ( 533)  467 98.2 2.1e-20
CCDS6609.1 GRHPR gene_id:9380|Hs108|chr9           ( 328)  314 69.4 6.1e-12


>>CCDS7643.1 CTBP2 gene_id:1488|Hs108|chr10               (445 aa)
 initn: 2973 init1: 2973 opt: 2973  Z-score: 3025.6  bits: 569.0 E(32554): 3.3e-162
Smith-Waterman score: 2973; 100.0% identity (100.0% similar) in 445 aa overlap (1-445:1-445)

               10        20        30        40        50        60
pF1KB3 MALVDKHKVKRQRLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 MALVDKHKVKRQRLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 DAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 DAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 IAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 IAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 ETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 ETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 LHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 LHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHES
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 EPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 EPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 FFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVAPGGLPAAMEGIIPGGIPVTHNLPTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 FFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVAPGGLPAAMEGIIPGGIPVTHNLPTV
              370       380       390       400       410       420

              430       440     
pF1KB3 AHPSQAPSPNQPTKHGDNREHPNEQ
       :::::::::::::::::::::::::
CCDS76 AHPSQAPSPNQPTKHGDNREHPNEQ
              430       440     

>>CCDS7644.1 CTBP2 gene_id:1488|Hs108|chr10               (985 aa)
 initn: 2837 init1: 2837 opt: 2837  Z-score: 2882.0  bits: 543.6 E(32554): 3.3e-154
Smith-Waterman score: 2837; 100.0% identity (100.0% similar) in 425 aa overlap (21-445:561-985)

                         10        20        30        40        50
pF1KB3           MALVDKHKVKRQRLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPI
                                     ::::::::::::::::::::::::::::::
CCDS76 LHTPHSPYQKVARRTGAPIIVSTMLAPEPSIRPQIMNGPLHPRPLVALLDGRDCTVEMPI
              540       550       560       570       580       590

               60        70        80        90       100       110
pF1KB3 LKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 LKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDN
              600       610       620       630       640       650

              120       130       140       150       160       170
pF1KB3 VDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVEQIRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 VDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVEQIRE
              660       670       680       690       700       710

              180       190       200       210       220       230
pF1KB3 VASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 VASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQ
              720       730       740       750       760       770

              240       250       260       270       280       290
pF1KB3 DLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 DLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRI
              780       790       800       810       820       830

              300       310       320       330       340       350
pF1KB3 RGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 RGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIP
              840       850       860       870       880       890

              360       370       380       390       400       410
pF1KB3 ESLRNCVNKEFFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVAPGGLPAAMEGIIPGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 ESLRNCVNKEFFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVAPGGLPAAMEGIIPGG
              900       910       920       930       940       950

              420       430       440     
pF1KB3 IPVTHNLPTVAHPSQAPSPNQPTKHGDNREHPNEQ
       :::::::::::::::::::::::::::::::::::
CCDS76 IPVTHNLPTVAHPSQAPSPNQPTKHGDNREHPNEQ
              960       970       980     

>>CCDS43203.1 CTBP1 gene_id:1487|Hs108|chr4               (429 aa)
 initn: 2405 init1: 2382 opt: 2417  Z-score: 2461.3  bits: 464.5 E(32554): 8.9e-131
Smith-Waterman score: 2417; 81.0% identity (95.5% similar) in 426 aa overlap (20-445:3-428)

               10        20        30        40        50        60
pF1KB3 MALVDKHKVKRQRLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFC
                          :.:: :::::::::::::::::::::::::::::.::::::
CCDS43                  MSGVRPPIMNGPLHPRPLVALLDGRDCTVEMPILKDVATVAFC
                                10        20        30        40   

               70        80        90       100       110       120
pF1KB3 DAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELG
       :::::::::::::::::::.:::::::::::::::::::.:::::::.::.:::.::.::
CCDS43 DAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLG
            50        60        70        80        90       100   

              130       140       150       160       170       180
pF1KB3 IAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRG
       :::::.:.:.::::::::.::::::::: :::.:::::::::::::::::::::::::::
CCDS43 IAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVEQIREVASGAARIRG
           110       120       130       140       150       160   

              190       200       210       220       230       240
pF1KB3 ETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVS
       ::::.::.::.:::::.:::::::.:.::::::.::.::.::.::: ::::::..::::.
CCDS43 ETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVT
           170       180       190       200       210       220   

              250       260       270       280       290       300
pF1KB3 LHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHES
       :::.:::::::::::::.:::::::::::.::::::::::::::::::::::::::::::
CCDS43 LHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHES
           230       240       250       260       270       280   

              310       320       330       340       350       360
pF1KB3 EPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKE
       :::::.:::::::::::::::.::::::::.:::: :: :::::::::::.::.:::::.
CCDS43 EPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKD
           290       300       310       320       330       340   

              370       380       390       400       410       420
pF1KB3 FFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVAPGGLPAAMEGIIPGGIPVTHNLPTV
        ..... :. .:  ..:::::::.::::::.::::: :.:::.:::.:... ..:.:: :
CCDS43 HLTAATHWASMDPAVVHPELNGAAYRYPPGVVGVAPTGIPAAVEGIVPSAMSLSHGLPPV
           350       360       370       380       390       400   

              430       440      
pF1KB3 AHPSQAPSPNQPTKHGDNREHPNEQ 
       ::: .::::.: .:   .:.: ..: 
CCDS43 AHPPHAPSPGQTVKPEADRDHASDQL
           410       420         

>>CCDS3348.1 CTBP1 gene_id:1487|Hs108|chr4                (440 aa)
 initn: 2405 init1: 2382 opt: 2417  Z-score: 2461.1  bits: 464.6 E(32554): 9.1e-131
Smith-Waterman score: 2417; 81.0% identity (95.5% similar) in 426 aa overlap (20-445:14-439)

               10        20        30        40        50        60
pF1KB3 MALVDKHKVKRQRLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFC
                          :.:: :::::::::::::::::::::::::::::.::::::
CCDS33       MGSSHLLNKGLPLGVRPPIMNGPLHPRPLVALLDGRDCTVEMPILKDVATVAFC
                     10        20        30        40        50    

               70        80        90       100       110       120
pF1KB3 DAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELG
       :::::::::::::::::::.:::::::::::::::::::.:::::::.::.:::.::.::
CCDS33 DAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLG
           60        70        80        90       100       110    

              130       140       150       160       170       180
pF1KB3 IAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRG
       :::::.:.:.::::::::.::::::::: :::.:::::::::::::::::::::::::::
CCDS33 IAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVEQIREVASGAARIRG
          120       130       140       150       160       170    

              190       200       210       220       230       240
pF1KB3 ETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVS
       ::::.::.::.:::::.:::::::.:.::::::.::.::.::.::: ::::::..::::.
CCDS33 ETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVT
          180       190       200       210       220       230    

              250       260       270       280       290       300
pF1KB3 LHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHES
       :::.:::::::::::::.:::::::::::.::::::::::::::::::::::::::::::
CCDS33 LHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHES
          240       250       260       270       280       290    

              310       320       330       340       350       360
pF1KB3 EPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKE
       :::::.:::::::::::::::.::::::::.:::: :: :::::::::::.::.:::::.
CCDS33 EPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKD
          300       310       320       330       340       350    

              370       380       390       400       410       420
pF1KB3 FFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVAPGGLPAAMEGIIPGGIPVTHNLPTV
        ..... :. .:  ..:::::::.::::::.::::: :.:::.:::.:... ..:.:: :
CCDS33 HLTAATHWASMDPAVVHPELNGAAYRYPPGVVGVAPTGIPAAVEGIVPSAMSLSHGLPPV
          360       370       380       390       400       410    

              430       440      
pF1KB3 AHPSQAPSPNQPTKHGDNREHPNEQ 
       ::: .::::.: .:   .:.: ..: 
CCDS33 AHPPHAPSPGQTVKPEADRDHASDQL
          420       430       440

>>CCDS904.1 PHGDH gene_id:26227|Hs108|chr1                (533 aa)
 initn: 350 init1: 170 opt: 467  Z-score: 479.8  bits: 98.2 E(32554): 2.1e-20
Smith-Waterman score: 467; 30.8% identity (57.4% similar) in 331 aa overlap (73-398:45-360)

             50        60        70        80        90       100  
pF1KB3 DCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIV
                                     :..  : ..  .  .: . ..  . :.:. 
CCDS90 LDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVG
           20        30        40        50        60        70    

            110       120       130       140       150       160  
pF1KB3 RIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRV
       : :.: ::::..:: . :: : : :..    .:. :   :. : :.      ....:   
CCDS90 RAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDG---
           80        90       100       110       120       130    

            170       180       190       200       210       220  
pF1KB3 QSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLG
        . :. . ...   .. :.:::..:.:: :. ::.: ..::...: ::: ..  .  :.:
CCDS90 -KWERKKFMGT---ELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFG
              140          150       160       170       180       

            230       240       250       260       270       280  
pF1KB3 VQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALA
       ::..  :...    : ...:  :   .  :.:: :. : ..:. .:: ::::.::: :: 
CCDS90 VQQL-PLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALL
       190        200       210       220       230       240      

            290       300       310       320       330       340  
pF1KB3 QALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIR
       .::. :.  ::::::   ::    .  : :  :.:  :: .  ...:. .  :  :... 
CCDS90 RALQSGQCAGAALDVFTEEPPR--DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFV
        250       260         270       280       290       300    

            350       360            370       380       390       
pF1KB3 RAITGRIPESLRNCVNKEFFVT-----SAPWSVIDQQAIHPELNGATYRYPPGIVGVAPG
         . :.   :: . :: . ...     . ::  :        :  :    : : . :   
CCDS90 DMVKGK---SLTGVVNAQALTSAFSPHTKPW--IGLAEALGTLMRAWAGSPKGTIQVITQ
          310          320       330         340       350         

       400       410       420       430       440                 
pF1KB3 GLPAAMEGIIPGGIPVTHNLPTVAHPSQAPSPNQPTKHGDNREHPNEQ            
       :                                                           
CCDS90 GTSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFG
     360       370       380       390       400       410         

>>CCDS6609.1 GRHPR gene_id:9380|Hs108|chr9                (328 aa)
 initn: 284 init1: 235 opt: 314  Z-score: 327.9  bits: 69.4 E(32554): 6.1e-12
Smith-Waterman score: 314; 27.8% identity (55.9% similar) in 313 aa overlap (54-354:23-327)

            30        40        50        60           70        80
pF1KB3 QIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQ---STQEIHEKVLNEAVGAM
                                     :: .: :...   : . :  : :...: : 
CCDS66         MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGV-AG
                       10        20        30        40         50 

               90             100       110       120       130    
pF1KB3 MYHTITLTREDLEK--FKA----LRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEET
        .  . :  . ..:  . :    :.::  .. : :.. .    . :: :   :.. .. :
CCDS66 AHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTT
              60        70        80        90       100       110 

          140       150       160       170       180       190    
pF1KB3 ADSTICHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQA
       :. ..  .:.  ::     . ...:  . : . .   . :   .   :.:.::.:: :::
CCDS66 AELAVSLLLTTCRRLPEAIEEVKNGGWT-SWKPLWLCGYG---LTQSTVGIIGLGRIGQA
             120       130        140       150          160       

          200       210       220        230       240       250   
pF1KB3 VAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVY-TLQDLLYQSDCVSLHCNLNEHNHHLI
       .: : : :: . ..:    :   :..   :  . .  .:  ::: . . :.:.  .. : 
CCDS66 IARRLKPFGVQRFLYTGR-QPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLC
       170       180        190       200       210       220      

            260       270       280       290       300       310  
pF1KB3 N-DFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKD
       : :: ...:.. : ..: .:: .:..  : :::  :.: .:.:::   ::.  .. ::  
CCDS66 NKDF-FQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLP-TNHPLLT
        230        240       250       260       270        280    

            320       330       340        350       360       370 
pF1KB3 APNLICTPHTAWYSEQASLEMREAAATEIRRAITGR-IPESLRNCVNKEFFVTSAPWSVI
         : .  :: .  ....   :   ::...  .. :. .:  :.                 
CCDS66 LKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSELKL                
          290       300       310       320                        

             380       390       400       410       420       430 
pF1KB3 DQQAIHPELNGATYRYPPGIVGVAPGGLPAAMEGIIPGGIPVTHNLPTVAHPSQAPSPNQ




445 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 02:14:51 2016 done: Fri Nov  4 02:14:52 2016
 Total Scan time:  2.270 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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