Result of FASTA (omim) for pF1KB3382
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3382, 421 aa
  1>>>pF1KB3382 421 - 421 aa - 421 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7765+/-0.000403; mu= 14.5953+/- 0.025
 mean_var=71.5226+/-14.505, 0's: 0 Z-trim(112.4): 132  B-trim: 68 in 1/50
 Lambda= 0.151654
 statistics sampled from 21164 (21299) to 21164 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.626), E-opt: 0.2 (0.25), width:  16
 Scan time:  8.100

The best scores are:                                      opt bits E(85289)
NP_001260 (OMIM: 179710) regulator of chromosome c ( 421) 2822 626.9  3e-179
NP_001041664 (OMIM: 179710) regulator of chromosom ( 421) 2822 626.9  3e-179
NP_001041660 (OMIM: 179710) regulator of chromosom ( 438) 2695 599.1 7.1e-171
NP_001041659 (OMIM: 179710) regulator of chromosom ( 452) 2676 594.9 1.3e-169
NP_061185 (OMIM: 609587) protein RCC2 [Homo sapien ( 522)  394 95.7   3e-19
NP_001129676 (OMIM: 609587) protein RCC2 [Homo sap ( 522)  394 95.7   3e-19
NP_001305434 (OMIM: 605200) probable E3 ubiquitin- ( 368)  310 77.2 7.4e-14
XP_016871530 (OMIM: 609248) PREDICTED: probable E3 ( 936)  311 77.6 1.4e-13
NP_001265114 (OMIM: 609248) probable E3 ubiquitin- ( 979)  311 77.6 1.5e-13
NP_056416 (OMIM: 609248) probable E3 ubiquitin-pro (1049)  311 77.6 1.6e-13
NP_071362 (OMIM: 609248) probable E3 ubiquitin-pro (1057)  311 77.6 1.6e-13
XP_005263389 (OMIM: 605200) PREDICTED: probable E3 ( 896)  310 77.4 1.6e-13
XP_005263388 (OMIM: 605200) PREDICTED: probable E3 ( 903)  310 77.4 1.6e-13
XP_016864296 (OMIM: 605200) PREDICTED: probable E3 ( 924)  310 77.4 1.7e-13
NP_001258531 (OMIM: 605200) probable E3 ubiquitin- ( 932)  310 77.4 1.7e-13
XP_005263387 (OMIM: 605200) PREDICTED: probable E3 ( 993)  310 77.4 1.8e-13
XP_005263386 (OMIM: 605200) PREDICTED: probable E3 (1042)  310 77.4 1.8e-13
XP_016864295 (OMIM: 605200) PREDICTED: probable E3 (1042)  310 77.4 1.8e-13
XP_005263384 (OMIM: 605200) PREDICTED: probable E3 (1050)  310 77.4 1.9e-13
NP_055421 (OMIM: 605200) probable E3 ubiquitin-pro (1050)  310 77.4 1.9e-13
NP_036271 (OMIM: 606051) secretion-regulating guan ( 458)  295 74.0 8.7e-13
NP_003913 (OMIM: 605109,617011) probable E3 ubiqui (4861)  298 75.1 4.4e-12
XP_016878194 (OMIM: 605109,617011) PREDICTED: prob (4883)  298 75.1 4.4e-12
XP_016878193 (OMIM: 605109,617011) PREDICTED: prob (4885)  298 75.1 4.4e-12
XP_016878192 (OMIM: 605109,617011) PREDICTED: prob (4891)  298 75.1 4.4e-12
XP_016878191 (OMIM: 605109,617011) PREDICTED: prob (4892)  298 75.1 4.4e-12
XP_016878190 (OMIM: 605109,617011) PREDICTED: prob (4892)  298 75.1 4.4e-12
XP_016878189 (OMIM: 605109,617011) PREDICTED: prob (4897)  298 75.1 4.4e-12
XP_016878188 (OMIM: 605109,617011) PREDICTED: prob (4909)  298 75.1 4.4e-12
XP_016879989 (OMIM: 609799,613824,615415) PREDICTE ( 666)  273 69.3 3.4e-11
XP_011537899 (OMIM: 609248) PREDICTED: probable E3 ( 960)  275 69.8 3.5e-11
NP_835464 (OMIM: 609799,613824,615415) serine/thre ( 692)  273 69.3 3.5e-11
XP_016879988 (OMIM: 609799,613824,615415) PREDICTE ( 705)  273 69.3 3.6e-11
XP_011537896 (OMIM: 609248) PREDICTED: probable E3 (1011)  275 69.8 3.6e-11
XP_011537897 (OMIM: 609248) PREDICTED: probable E3 (1011)  275 69.8 3.6e-11
XP_011522942 (OMIM: 609799,613824,615415) PREDICTE ( 716)  273 69.3 3.6e-11
XP_011522940 (OMIM: 609799,613824,615415) PREDICTE ( 729)  273 69.3 3.7e-11
XP_011537895 (OMIM: 609248) PREDICTED: probable E3 (1073)  275 69.8 3.8e-11
XP_011537894 (OMIM: 609248) PREDICTED: probable E3 (1081)  275 69.8 3.8e-11
XP_016878186 (OMIM: 176270,227220,605837,615516) P (2556)  271 69.1 1.5e-10
XP_016878187 (OMIM: 176270,227220,605837,615516) P (2556)  271 69.1 1.5e-10
XP_011520435 (OMIM: 176270,227220,605837,615516) P (3749)  271 69.1 2.1e-10
XP_011520433 (OMIM: 176270,227220,605837,615516) P (4673)  271 69.2 2.5e-10
XP_006720790 (OMIM: 176270,227220,605837,615516) P (4748)  271 69.2 2.6e-10
XP_005268333 (OMIM: 176270,227220,605837,615516) P (4796)  271 69.2 2.6e-10
XP_016878184 (OMIM: 176270,227220,605837,615516) P (4796)  271 69.2 2.6e-10
XP_016878185 (OMIM: 176270,227220,605837,615516) P (4796)  271 69.2 2.6e-10
XP_006720789 (OMIM: 176270,227220,605837,615516) P (4829)  271 69.2 2.6e-10
NP_004658 (OMIM: 176270,227220,605837,615516) E3 u (4834)  271 69.2 2.6e-10
NP_001158608 (OMIM: 609249) probable E3 ubiquitin- ( 986)  261 66.7   3e-10


>>NP_001260 (OMIM: 179710) regulator of chromosome conde  (421 aa)
 initn: 2822 init1: 2822 opt: 2822  Z-score: 3339.1  bits: 626.9 E(85289): 3e-179
Smith-Waterman score: 2822; 100.0% identity (100.0% similar) in 421 aa overlap (1-421:1-421)

               10        20        30        40        50        60
pF1KB3 MSPKRIAKRRSPPADAIPKSKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSPKRIAKRRSPPADAIPKSKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 ALVSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 VVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 NDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 RFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 GGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAVSSVACGASVGYAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAVSSVACGASVGYAV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 TKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQ
              370       380       390       400       410       420

        
pF1KB3 S
       :
NP_001 S
        

>>NP_001041664 (OMIM: 179710) regulator of chromosome co  (421 aa)
 initn: 2822 init1: 2822 opt: 2822  Z-score: 3339.1  bits: 626.9 E(85289): 3e-179
Smith-Waterman score: 2822; 100.0% identity (100.0% similar) in 421 aa overlap (1-421:1-421)

               10        20        30        40        50        60
pF1KB3 MSPKRIAKRRSPPADAIPKSKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSPKRIAKRRSPPADAIPKSKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 ALVSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 VVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 NDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 RFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 GGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAVSSVACGASVGYAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAVSSVACGASVGYAV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 TKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQ
              370       380       390       400       410       420

        
pF1KB3 S
       :
NP_001 S
        

>>NP_001041660 (OMIM: 179710) regulator of chromosome co  (438 aa)
 initn: 2682 init1: 2682 opt: 2695  Z-score: 3188.7  bits: 599.1 E(85289): 7.1e-171
Smith-Waterman score: 2778; 96.1% identity (96.1% similar) in 438 aa overlap (1-421:1-438)

               10        20                         30        40   
pF1KB3 MSPKRIAKRRSPPADAIPKSKKVK-----------------VSHRSHSTEPGLVLTLGQG
       ::::::::::::::::::::::::                 :::::::::::::::::::
NP_001 MSPKRIAKRRSPPADAIPKSKKVKDTRAAASRRVPGARSCQVSHRSHSTEPGLVLTLGQG
               10        20        30        40        50        60

            50        60        70        80        90       100   
pF1KB3 DVGQLGLGENVMERKKPALVSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVGQLGLGENVMERKKPALVSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDT
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KB3 SVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSM
              130       140       150       160       170       180

           170       180       190       200       210       220   
pF1KB3 VPVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERL
              190       200       210       220       230       240

           230       240       250       260       270       280   
pF1KB3 LVPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIP
              250       260       270       280       290       300

           290       300       310       320       330       340   
pF1KB3 QNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISR
              310       320       330       340       350       360

           350       360       370       380       390       400   
pF1KB3 LPAVSSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPAVSSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLS
              370       380       390       400       410       420

           410       420 
pF1KB3 VSSGGQHTVLLVKDKEQS
       ::::::::::::::::::
NP_001 VSSGGQHTVLLVKDKEQS
              430        

>>NP_001041659 (OMIM: 179710) regulator of chromosome co  (452 aa)
 initn: 2808 init1: 2665 opt: 2676  Z-score: 3166.0  bits: 594.9 E(85289): 1.3e-169
Smith-Waterman score: 2750; 93.1% identity (93.1% similar) in 452 aa overlap (1-421:1-452)

               10        20                                        
pF1KB3 MSPKRIAKRRSPPADAIPKSKKVK-------------------------------VSHRS
       ::::::::::::::::::::::::                               :::::
NP_001 MSPKRIAKRRSPPADAIPKSKKVKDTRAAASRRVPGARSCQGACGPSPPDQKTRPVSHRS
               10        20        30        40        50        60

      30        40        50        60        70        80         
pF1KB3 HSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPEDVVQAEAGGMHTVCLSKSGQVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPEDVVQAEAGGMHTVCLSKSGQVY
               70        80        90       100       110       120

      90       100       110       120       130       140         
pF1KB3 SFGCNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGSFRDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFGCNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGSFRDN
              130       140       150       160       170       180

     150       160       170       180       190       200         
pF1KB3 NGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPE
              190       200       210       220       230       240

     210       220       230       240       250       260         
pF1KB3 LFANRGGRQGLERLLVPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFANRGGRQGLERLLVPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNY
              250       260       270       280       290       300

     270       280       290       300       310       320         
pF1KB3 HQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLG
              310       320       330       340       350       360

     330       340       350       360       370       380         
pF1KB3 EGAEEKSIPTLISRLPAVSSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGAEEKSIPTLISRLPAVSSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPV
              370       380       390       400       410       420

     390       400       410       420 
pF1KB3 EMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS
       ::::::::::::::::::::::::::::::::
NP_001 EMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS
              430       440       450  

>>NP_061185 (OMIM: 609587) protein RCC2 [Homo sapiens]    (522 aa)
 initn: 272 init1: 111 opt: 394  Z-score: 466.7  bits: 95.7 E(85289): 3e-19
Smith-Waterman score: 394; 24.8% identity (58.1% similar) in 387 aa overlap (50-421:132-506)

      20        30        40        50         60        70        
pF1KB3 SKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVM-ERKKPALVSIPEDVVQAEAGGMH
                                     ::.:.   ..   :...   .: . . . :
NP_061 CKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAH
             110       120       130       140       150       160 

       80        90       100         110       120       130      
pF1KB3 TVCLSKSGQVYSFGCNDEGALGR-DTS-VEGSEMVPGKVELQEKVVQVSAGDSHTAALTD
       .. ..  :...:.: :..: ::. ::. ::. ... :    .: .:... : .:: :::.
NP_061 SLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLS--HEVIVSAACGRNHTLALTE
             170       180       190       200         210         

        140       150       160       170        180       190     
pF1KB3 DGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASGNDHLVMLTADGDLYT
        : :: .:  ... : .:: .       :.:.. .  :..:.: : .  ...   :.::.
NP_061 TGSVFAFG--ENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYS
     220         230       240       250       260       270       

         200        210       220       230              240       
pF1KB3 LGCGEQGQLGRVPE-LFANRGGRQGLERLLVPKCVML---KSRGSR----GHVRFQDAFC
       .:: : ::::.  .  :  :. :   .  :::. : .   :.. ..     .:  .:. :
NP_061 FGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVAC
       280       290       300       310       320       330       

       250       260       270       280       290       300       
pF1KB3 GAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTV
       ::  :.... . .:...:...: .::    .. ..:. .  :    ..   . .:   . 
NP_061 GANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSF
       340       350       360       370       380       390       

       310       320       330       340         350       360     
pF1KB3 CMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTKDGR
        ..  :  .  : .. .:       :    :  .. : .  . :.::: : .  :. :  
NP_061 AVSEVGGLFFWGATNTSR-------ESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADES
       400       410              420       430       440          

         370        380       390       400       410       420    
pF1KB3 VFAWGMGTNY-QLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS   
       ...:: . .. .:: :. .   : . .  : :..    .:. : .:......:. ..   
NP_061 TISWGPSPTFGELGYGDHKPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESETEKE
     450       460       470       480       490       500         

NP_061 KIKKLPEYNPRTL
     510       520  

>>NP_001129676 (OMIM: 609587) protein RCC2 [Homo sapiens  (522 aa)
 initn: 272 init1: 111 opt: 394  Z-score: 466.7  bits: 95.7 E(85289): 3e-19
Smith-Waterman score: 394; 24.8% identity (58.1% similar) in 387 aa overlap (50-421:132-506)

      20        30        40        50         60        70        
pF1KB3 SKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVM-ERKKPALVSIPEDVVQAEAGGMH
                                     ::.:.   ..   :...   .: . . . :
NP_001 CKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAH
             110       120       130       140       150       160 

       80        90       100         110       120       130      
pF1KB3 TVCLSKSGQVYSFGCNDEGALGR-DTS-VEGSEMVPGKVELQEKVVQVSAGDSHTAALTD
       .. ..  :...:.: :..: ::. ::. ::. ... :    .: .:... : .:: :::.
NP_001 SLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLS--HEVIVSAACGRNHTLALTE
             170       180       190       200         210         

        140       150       160       170        180       190     
pF1KB3 DGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASGNDHLVMLTADGDLYT
        : :: .:  ... : .:: .       :.:.. .  :..:.: : .  ...   :.::.
NP_001 TGSVFAFG--ENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYS
     220         230       240       250       260       270       

         200        210       220       230              240       
pF1KB3 LGCGEQGQLGRVPE-LFANRGGRQGLERLLVPKCVML---KSRGSR----GHVRFQDAFC
       .:: : ::::.  .  :  :. :   .  :::. : .   :.. ..     .:  .:. :
NP_001 FGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVAC
       280       290       300       310       320       330       

       250       260       270       280       290       300       
pF1KB3 GAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTV
       ::  :.... . .:...:...: .::    .. ..:. .  :    ..   . .:   . 
NP_001 GANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSF
       340       350       360       370       380       390       

       310       320       330       340         350       360     
pF1KB3 CMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTKDGR
        ..  :  .  : .. .:       :    :  .. : .  . :.::: : .  :. :  
NP_001 AVSEVGGLFFWGATNTSR-------ESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADES
       400       410              420       430       440          

         370        380       390       400       410       420    
pF1KB3 VFAWGMGTNY-QLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS   
       ...:: . .. .:: :. .   : . .  : :..    .:. : .:......:. ..   
NP_001 TISWGPSPTFGELGYGDHKPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESETEKE
     450       460       470       480       490       500         

NP_001 KIKKLPEYNPRTL
     510       520  

>>NP_001305434 (OMIM: 605200) probable E3 ubiquitin-prot  (368 aa)
 initn: 268 init1: 191 opt: 310  Z-score: 369.8  bits: 77.2 E(85289): 7.4e-14
Smith-Waterman score: 362; 30.4% identity (57.3% similar) in 286 aa overlap (127-407:92-357)

        100       110       120       130       140       150      
pF1KB3 GALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLL
                                     :.::. ::.: :..: ::.  :  : .::.
NP_001 TKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSD--GQLGLM
              70        80        90       100       110           

        160        170        180       190       200       210    
pF1KB3 EPMKKSMVPVQVQ-LDVP-VVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANR
           .  ::  .: :.   ...:. :: : . :.:::...: : . .::::   : : ..
NP_001 TTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKE-FPSQ
     120       130       140       150       160       170         

          220       230       240       250       260       270    
pF1KB3 GGRQGLERLLVPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGT
       .. :             . :. .:    : :  ::. .::.:  : :.:.:..:  ::: 
NP_001 ASPQ-------------RVRSLEGIPLAQVAAGGAH-SFALSLSGAVFGWGMNNAGQLGL
      180                    190       200        210       220    

          280       290       300       310       320       330    
pF1KB3 PGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEE
          ..   : ..  ..  :.. : .: :..::. . . : ....: .  :.::     .:
NP_001 SDEKDRESPCHVKLLR--TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDE
          230       240         250       260       270       280  

          340         350        360       370       380       390 
pF1KB3 KSIPTLISRL--PAVSSVACGASVGYA-VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEM
        . :  . .:    :...::: .   : : ..: ..:.: :.  :::::.  ..  :  .
NP_001 VN-PRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPV
             290       300       310       320       330       340 

             400       410       420 
pF1KB3 MGKQLENRVVLSVSSGGQHTVLLVKDKEQS
        :    .   ::. .:              
NP_001 KGYWAAHSGQLSARAGKNDCLWNLKVF   
             350       360           

>>XP_016871530 (OMIM: 609248) PREDICTED: probable E3 ubi  (936 aa)
 initn: 308 init1: 155 opt: 311  Z-score: 364.6  bits: 77.6 E(85289): 1.4e-13
Smith-Waterman score: 515; 31.1% identity (60.2% similar) in 367 aa overlap (37-393:1-343)

         10        20        30        40        50            60  
pF1KB3 AKRRSPPADAIPKSKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLG----ENVMERKKPAL
                                     .:  :... ::::::    : :.: .:  .
XP_016                               MLCWGNASFGQLGLGGIDEEIVLEPRKSDF
                                             10        20        30

             70        80        90       100       110        120 
pF1KB3 VSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQ-EKV
         : . : ..  :  ::: .  .: ::. :::: : ::.. : .  :.:   : :. ...
XP_016 F-INKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQV---VALDAQNI
                40        50        60        70           80      

             130       140       150       160       170           
pF1KB3 VQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQL--DVPVVKVAS
       : :: :..:: ::.: :.:. ::   :..: .::.   .   :: ...   :. .:.:: 
XP_016 VAVSCGEAHTLALNDKGQVYAWGL--DSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVAC
         90       100       110         120       130       140    

     180       190       200       210       220       230         
pF1KB3 GNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGH
       :  : . :.  ....  : .. ::::     ...   .:   .::  : ..    :    
XP_016 GYYHSLALSKASEVFCWGQNKYGQLG-----LGTDCKKQTSPQLL--KSLL----G----
          150       160       170            180                   

     240       250       260       270       280       290         
pF1KB3 VRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGF
       . :...  :.  .:...  : ..:.: ... :::    .. ..:. : :..  ... : .
XP_016 IPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR--SQKIVYI
     190       200       210       220       230       240         

     300       310       320       330       340         350       
pF1KB3 SGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRL--PAVSSVACGASVG
         :. ::. . .:: ....: . ::.:: .  ..: . :  . .:    :. .::: .  
XP_016 CCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEIN-PRKVFELMGSIVTEIACGRQHT
       250       260       270       280        290       300      

        360       370       380       390       400       410      
pF1KB3 YA-VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVK
        : : ..::....:.: : :::::.  .  ::  . :                       
XP_016 SAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEEYFCVKR
        310       320       330       340       350       360      

        420                                                        
pF1KB3 DKEQS                                                       
                                                                   
XP_016 IFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPVEIANEI
        370       380       390       400       410       420      

>>NP_001265114 (OMIM: 609248) probable E3 ubiquitin-prot  (979 aa)
 initn: 308 init1: 155 opt: 311  Z-score: 364.3  bits: 77.6 E(85289): 1.5e-13
Smith-Waterman score: 515; 31.1% identity (60.2% similar) in 367 aa overlap (37-393:1-343)

         10        20        30        40        50            60  
pF1KB3 AKRRSPPADAIPKSKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLG----ENVMERKKPAL
                                     .:  :... ::::::    : :.: .:  .
NP_001                               MLCWGNASFGQLGLGGIDEEIVLEPRKSDF
                                             10        20        30

             70        80        90       100       110        120 
pF1KB3 VSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQ-EKV
         : . : ..  :  ::: .  .: ::. :::: : ::.. : .  :.:   : :. ...
NP_001 F-INKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQV---VALDAQNI
                40        50        60        70           80      

             130       140       150       160       170           
pF1KB3 VQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQL--DVPVVKVAS
       : :: :..:: ::.: :.:. ::   :..: .::.   .   :: ...   :. .:.:: 
NP_001 VAVSCGEAHTLALNDKGQVYAWGL--DSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVAC
         90       100       110         120       130       140    

     180       190       200       210       220       230         
pF1KB3 GNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGH
       :  : . :.  ....  : .. ::::     ...   .:   .::  : ..    :    
NP_001 GYYHSLALSKASEVFCWGQNKYGQLG-----LGTDCKKQTSPQLL--KSLL----G----
          150       160       170            180                   

     240       250       260       270       280       290         
pF1KB3 VRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGF
       . :...  :.  .:...  : ..:.: ... :::    .. ..:. : :..  ... : .
NP_001 IPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR--SQKIVYI
     190       200       210       220       230       240         

     300       310       320       330       340         350       
pF1KB3 SGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRL--PAVSSVACGASVG
         :. ::. . .:: ....: . ::.:: .  ..: . :  . .:    :. .::: .  
NP_001 CCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEIN-PRKVFELMGSIVTEIACGRQHT
       250       260       270       280        290       300      

        360       370       380       390       400       410      
pF1KB3 YA-VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVK
        : : ..::....:.: : :::::.  .  ::  . :                       
NP_001 SAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEEYFCVKR
        310       320       330       340       350       360      

        420                                                        
pF1KB3 DKEQS                                                       
                                                                   
NP_001 IFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPVEIANEI
        370       380       390       400       410       420      

>>NP_056416 (OMIM: 609248) probable E3 ubiquitin-protein  (1049 aa)
 initn: 308 init1: 155 opt: 311  Z-score: 363.8  bits: 77.6 E(85289): 1.6e-13
Smith-Waterman score: 515; 31.1% identity (60.2% similar) in 367 aa overlap (37-393:1-343)

         10        20        30        40        50            60  
pF1KB3 AKRRSPPADAIPKSKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLG----ENVMERKKPAL
                                     .:  :... ::::::    : :.: .:  .
NP_056                               MLCWGNASFGQLGLGGIDEEIVLEPRKSDF
                                             10        20        30

             70        80        90       100       110        120 
pF1KB3 VSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQ-EKV
         : . : ..  :  ::: .  .: ::. :::: : ::.. : .  :.:   : :. ...
NP_056 F-INKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQV---VALDAQNI
                40        50        60        70           80      

             130       140       150       160       170           
pF1KB3 VQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQL--DVPVVKVAS
       : :: :..:: ::.: :.:. ::   :..: .::.   .   :: ...   :. .:.:: 
NP_056 VAVSCGEAHTLALNDKGQVYAWGL--DSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVAC
         90       100       110         120       130       140    

     180       190       200       210       220       230         
pF1KB3 GNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGH
       :  : . :.  ....  : .. ::::     ...   .:   .::  : ..    :    
NP_056 GYYHSLALSKASEVFCWGQNKYGQLG-----LGTDCKKQTSPQLL--KSLL----G----
          150       160       170            180                   

     240       250       260       270       280       290         
pF1KB3 VRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGF
       . :...  :.  .:...  : ..:.: ... :::    .. ..:. : :..  ... : .
NP_056 IPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR--SQKIVYI
     190       200       210       220       230       240         

     300       310       320       330       340         350       
pF1KB3 SGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRL--PAVSSVACGASVG
         :. ::. . .:: ....: . ::.:: .  ..: . :  . .:    :. .::: .  
NP_056 CCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEIN-PRKVFELMGSIVTEIACGRQHT
       250       260       270       280        290       300      

        360       370       380       390       400       410      
pF1KB3 YA-VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVK
        : : ..::....:.: : :::::.  .  ::  . :                       
NP_056 SAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEEYFCVKR
        310       320       330       340       350       360      

        420                                                        
pF1KB3 DKEQS                                                       
                                                                   
NP_056 IFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPVEIANEI
        370       380       390       400       410       420      




421 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 12:09:41 2016 done: Sat Nov  5 12:09:42 2016
 Total Scan time:  8.100 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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