FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3384, 699 aa
1>>>pF1KB3384 699 - 699 aa - 699 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.7306+/-0.000441; mu= -5.1431+/- 0.028
mean_var=495.2501+/-100.865, 0's: 0 Z-trim(124.7): 120 B-trim: 676 in 1/58
Lambda= 0.057632
statistics sampled from 46637 (46782) to 46637 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.549), width: 16
Scan time: 13.210
The best scores are: opt bits E(85289)
NP_872634 (OMIM: 602980) SRSF protein kinase 2 iso ( 699) 4804 414.1 9.4e-115
XP_016868051 (OMIM: 602980) PREDICTED: SRSF protei ( 780) 4777 411.9 4.8e-114
XP_016868052 (OMIM: 602980) PREDICTED: SRSF protei ( 780) 4719 407.0 1.4e-112
NP_872633 (OMIM: 602980) SRSF protein kinase 2 iso ( 688) 4653 401.5 5.6e-111
XP_016868055 (OMIM: 602980) PREDICTED: SRSF protei ( 688) 4653 401.5 5.6e-111
NP_001265202 (OMIM: 602980) SRSF protein kinase 2 ( 688) 4653 401.5 5.6e-111
XP_016868049 (OMIM: 602980) PREDICTED: SRSF protei ( 725) 4653 401.5 5.8e-111
XP_016868050 (OMIM: 602980) PREDICTED: SRSF protei ( 688) 4595 396.7 1.6e-109
XP_005250607 (OMIM: 602980) PREDICTED: SRSF protei ( 730) 4373 378.3 5.9e-104
XP_005250606 (OMIM: 602980) PREDICTED: SRSF protei ( 811) 4346 376.1 3e-103
XP_011514838 (OMIM: 602980) PREDICTED: SRSF protei ( 730) 4223 365.8 3.4e-100
XP_006716161 (OMIM: 602980) PREDICTED: SRSF protei ( 719) 4222 365.7 3.5e-100
XP_005250608 (OMIM: 602980) PREDICTED: SRSF protei ( 719) 4222 365.7 3.5e-100
XP_016868053 (OMIM: 602980) PREDICTED: SRSF protei ( 719) 4222 365.7 3.5e-100
XP_011514840 (OMIM: 602980) PREDICTED: SRSF protei ( 719) 4222 365.7 3.5e-100
XP_016868054 (OMIM: 602980) PREDICTED: SRSF protei ( 618) 3849 334.6 6.9e-91
NP_003128 (OMIM: 601939) SRSF protein kinase 1 [Ho ( 655) 1527 141.6 9.4e-33
>>NP_872634 (OMIM: 602980) SRSF protein kinase 2 isoform (699 aa)
initn: 4804 init1: 4804 opt: 4804 Z-score: 2181.2 bits: 414.1 E(85289): 9.4e-115
Smith-Waterman score: 4804; 100.0% identity (100.0% similar) in 699 aa overlap (1-699:1-699)
10 20 30 40 50 60
pF1KB3 MSSRKVLAIQARKRRPKREKHPKKPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 MSSRKVLAIQARKRRPKREKHPKKPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 LGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 KVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 GHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 RRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 IEELEREAERKIIEENITSAAPSNDQDGEYCPEVKLKTTGLEEAAEAETAKDNGEAEDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 IEELEREAERKIIEENITSAAPSNDQDGEYCPEVKLKTTGLEEAAEAETAKDNGEAEDQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLEQQLDDEDDDEEDCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 EKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLEQQLDDEDDDEEDCP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 NPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGSLEPVACGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 NPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGSLEPVACGS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKAKTRAADLLVNPLDPRNADKIRVKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 VLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKAKTRAADLLVNPLDPRNADKIRVKIA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 DLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 DLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 EDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 EDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKY
610 620 630 640 650 660
670 680 690
pF1KB3 GWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS
:::::::::::::::::::::::::::::::::::::::
NP_872 GWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS
670 680 690
>>XP_016868051 (OMIM: 602980) PREDICTED: SRSF protein ki (780 aa)
initn: 4777 init1: 4777 opt: 4777 Z-score: 2168.5 bits: 411.9 E(85289): 4.8e-114
Smith-Waterman score: 4777; 99.9% identity (100.0% similar) in 695 aa overlap (5-699:86-780)
10 20 30
pF1KB3 MSSRKVLAIQARKRRPKREKHPKKPEPQQKAPLV
.:::::::::::::::::::::::::::::
XP_016 EKRPREERWCETRGGAGQGRAHGAAGGATGRVLAIQARKRRPKREKHPKKPEPQQKAPLV
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB3 PPPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHV
120 130 140 150 160 170
100 110 120 130 140 150
pF1KB3 IRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPNKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPNKD
180 190 200 210 220 230
160 170 180 190 200 210
pF1KB3 MVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDY
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB3 LHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGK
300 310 320 330 340 350
280 290 300 310 320 330
pF1KB3 ISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKIIEENITSAAPSNDQDGEYCPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKIIEENITSAAPSNDQDGEYCPEV
360 370 380 390 400 410
340 350 360 370 380 390
pF1KB3 KLKTTGLEEAAEAETAKDNGEAEDQEEKEDAEKENIEKDEDDVDQELANIDPTWIESPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLKTTGLEEAAEAETAKDNGEAEDQEEKEDAEKENIEKDEDDVDQELANIDPTWIESPKT
420 430 440 450 460 470
400 410 420 430 440 450
pF1KB3 NGHIENGPFSLEQQLDDEDDDEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGHIENGPFSLEQQLDDEDDDEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRH
480 490 500 510 520 530
460 470 480 490 500 510
pF1KB3 KIPESQFPEFSTSLFSGSLEPVACGSVLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIPESQFPEFSTSLFSGSLEPVACGSVLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPK
540 550 560 570 580 590
520 530 540 550 560 570
pF1KB3 AKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYST
600 610 620 630 640 650
580 590 600 610 620 630
pF1KB3 PADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREF
660 670 680 690 700 710
640 650 660 670 680 690
pF1KB3 FNRRGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNRRGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRH
720 730 740 750 760 770
pF1KB3 PWLNS
:::::
XP_016 PWLNS
780
>>XP_016868052 (OMIM: 602980) PREDICTED: SRSF protein ki (780 aa)
initn: 4719 init1: 4719 opt: 4719 Z-score: 2142.4 bits: 407.0 E(85289): 1.4e-112
Smith-Waterman score: 4719; 98.4% identity (99.7% similar) in 695 aa overlap (5-699:86-780)
10 20 30
pF1KB3 MSSRKVLAIQARKRRPKREKHPKKPEPQQKAPLV
.:::::::::::::::::::::::::::::
XP_016 EKRPREERWCETRGGAGQGRAHGAAGGATGRVLAIQARKRRPKREKHPKKPEPQQKAPLV
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB3 PPPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHV
120 130 140 150 160 170
100 110 120 130 140 150
pF1KB3 IRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPNKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPNKD
180 190 200 210 220 230
160 170 180 190 200 210
pF1KB3 MVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDY
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB3 LHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGK
300 310 320 330 340 350
280 290 300 310 320 330
pF1KB3 ISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKIIEENITSAAPSNDQDGEYCPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKIIEENITSAAPSNDQDGEYCPEV
360 370 380 390 400 410
340 350 360 370 380 390
pF1KB3 KLKTTGLEEAAEAETAKDNGEAEDQEEKEDAEKENIEKDEDDVDQELANIDPTWIESPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLKTTGLEEAAEAETAKDNGEAEDQEEKEDAEKENIEKDEDDVDQELANIDPTWIESPKT
420 430 440 450 460 470
400 410 420 430 440 450
pF1KB3 NGHIENGPFSLEQQLDDEDDDEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGHIENGPFSLEQQLDDEDDDEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRH
480 490 500 510 520 530
460 470 480 490 500 510
pF1KB3 KIPESQFPEFSTSLFSGSLEPVACGSVLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIPESQFPEFSTSLFSGSLEPVACGSVLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPK
540 550 560 570 580 590
520 530 540 550 560 570
pF1KB3 AKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYST
600 610 620 630 640 650
580 590 600 610 620 630
pF1KB3 PADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREF
::::::::::::::::::::::::::::::::::::: ::::::..::..:. ::::.::
XP_016 PADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIALIIELLGKVPRKYAMLGKYSKEF
660 670 680 690 700 710
640 650 660 670 680 690
pF1KB3 FNRRGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRH
:.:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTRKGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRH
720 730 740 750 760 770
pF1KB3 PWLNS
:::::
XP_016 PWLNS
780
>>NP_872633 (OMIM: 602980) SRSF protein kinase 2 isoform (688 aa)
initn: 4653 init1: 4653 opt: 4653 Z-score: 2113.4 bits: 401.5 E(85289): 5.6e-111
Smith-Waterman score: 4653; 98.8% identity (99.6% similar) in 683 aa overlap (17-699:6-688)
10 20 30 40 50 60
pF1KB3 MSSRKVLAIQARKRRPKREKHPKKPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEI
.. . ..::::::::::::::::::::::::::::::::::::
NP_872 MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEI
10 20 30 40
70 80 90 100 110 120
pF1KB3 LGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 LGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAM
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB3 KVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 KVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB3 GHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 GHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB3 RRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 RRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB3 IEELEREAERKIIEENITSAAPSNDQDGEYCPEVKLKTTGLEEAAEAETAKDNGEAEDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 IEELEREAERKIIEENITSAAPSNDQDGEYCPEVKLKTTGLEEAAEAETAKDNGEAEDQE
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB3 EKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLEQQLDDEDDDEEDCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 EKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLEQQLDDEDDDEEDCP
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB3 NPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGSLEPVACGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 NPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGSLEPVACGS
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB3 VLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKAKTRAADLLVNPLDPRNADKIRVKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 VLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKAKTRAADLLVNPLDPRNADKIRVKIA
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB3 DLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 DLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSG
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB3 EDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 EDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKY
590 600 610 620 630 640
670 680 690
pF1KB3 GWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS
:::::::::::::::::::::::::::::::::::::::
NP_872 GWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS
650 660 670 680
>>XP_016868055 (OMIM: 602980) PREDICTED: SRSF protein ki (688 aa)
initn: 4653 init1: 4653 opt: 4653 Z-score: 2113.4 bits: 401.5 E(85289): 5.6e-111
Smith-Waterman score: 4653; 98.8% identity (99.6% similar) in 683 aa overlap (17-699:6-688)
10 20 30 40 50 60
pF1KB3 MSSRKVLAIQARKRRPKREKHPKKPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEI
.. . ..::::::::::::::::::::::::::::::::::::
XP_016 MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEI
10 20 30 40
70 80 90 100 110 120
pF1KB3 LGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAM
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB3 KVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB3 GHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB3 RRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB3 IEELEREAERKIIEENITSAAPSNDQDGEYCPEVKLKTTGLEEAAEAETAKDNGEAEDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEELEREAERKIIEENITSAAPSNDQDGEYCPEVKLKTTGLEEAAEAETAKDNGEAEDQE
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB3 EKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLEQQLDDEDDDEEDCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLEQQLDDEDDDEEDCP
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB3 NPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGSLEPVACGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGSLEPVACGS
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB3 VLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKAKTRAADLLVNPLDPRNADKIRVKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKAKTRAADLLVNPLDPRNADKIRVKIA
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB3 DLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSG
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB3 EDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKY
590 600 610 620 630 640
670 680 690
pF1KB3 GWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS
:::::::::::::::::::::::::::::::::::::::
XP_016 GWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS
650 660 670 680
>>NP_001265202 (OMIM: 602980) SRSF protein kinase 2 isof (688 aa)
initn: 4653 init1: 4653 opt: 4653 Z-score: 2113.4 bits: 401.5 E(85289): 5.6e-111
Smith-Waterman score: 4653; 98.8% identity (99.6% similar) in 683 aa overlap (17-699:6-688)
10 20 30 40 50 60
pF1KB3 MSSRKVLAIQARKRRPKREKHPKKPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEI
.. . ..::::::::::::::::::::::::::::::::::::
NP_001 MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEI
10 20 30 40
70 80 90 100 110 120
pF1KB3 LGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAM
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB3 KVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB3 GHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB3 RRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB3 IEELEREAERKIIEENITSAAPSNDQDGEYCPEVKLKTTGLEEAAEAETAKDNGEAEDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEELEREAERKIIEENITSAAPSNDQDGEYCPEVKLKTTGLEEAAEAETAKDNGEAEDQE
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB3 EKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLEQQLDDEDDDEEDCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLEQQLDDEDDDEEDCP
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB3 NPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGSLEPVACGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGSLEPVACGS
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB3 VLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKAKTRAADLLVNPLDPRNADKIRVKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKAKTRAADLLVNPLDPRNADKIRVKIA
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB3 DLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSG
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB3 EDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKY
590 600 610 620 630 640
670 680 690
pF1KB3 GWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS
:::::::::::::::::::::::::::::::::::::::
NP_001 GWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS
650 660 670 680
>>XP_016868049 (OMIM: 602980) PREDICTED: SRSF protein ki (725 aa)
initn: 4653 init1: 4653 opt: 4653 Z-score: 2113.1 bits: 401.5 E(85289): 5.8e-111
Smith-Waterman score: 4653; 98.8% identity (99.6% similar) in 683 aa overlap (17-699:43-725)
10 20 30 40
pF1KB3 MSSRKVLAIQARKRRPKREKHPKKPEPQQKAPLVPPPPPPPPPPPP
.. . ..::::::::::::::::::::::
XP_016 PFRPESGGRKERNIRKKIKQKIELLMSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPP
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB3 PLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTV
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB3 WLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKIS
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB3 GMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDI
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB3 KPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKK
260 270 280 290 300 310
290 300 310 320 330 340
pF1KB3 QKRQAELLEKRLQEIEELEREAERKIIEENITSAAPSNDQDGEYCPEVKLKTTGLEEAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKRQAELLEKRLQEIEELEREAERKIIEENITSAAPSNDQDGEYCPEVKLKTTGLEEAAE
320 330 340 350 360 370
350 360 370 380 390 400
pF1KB3 AETAKDNGEAEDQEEKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AETAKDNGEAEDQEEKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLE
380 390 400 410 420 430
410 420 430 440 450 460
pF1KB3 QQLDDEDDDEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQLDDEDDDEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFST
440 450 460 470 480 490
470 480 490 500 510 520
pF1KB3 SLFSGSLEPVACGSVLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKAKTRAADLLVNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLFSGSLEPVACGSVLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKAKTRAADLLVNP
500 510 520 530 540 550
530 540 550 560 570 580
pF1KB3 LDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAF
560 570 580 590 600 610
590 600 610 620 630 640
pF1KB3 ELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITK
620 630 640 650 660 670
650 660 670 680 690
pF1KB3 LKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS
680 690 700 710 720
>>XP_016868050 (OMIM: 602980) PREDICTED: SRSF protein ki (688 aa)
initn: 4595 init1: 4595 opt: 4595 Z-score: 2087.3 bits: 396.7 E(85289): 1.6e-109
Smith-Waterman score: 4595; 97.4% identity (99.3% similar) in 683 aa overlap (17-699:6-688)
10 20 30 40 50 60
pF1KB3 MSSRKVLAIQARKRRPKREKHPKKPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEI
.. . ..::::::::::::::::::::::::::::::::::::
XP_016 MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEI
10 20 30 40
70 80 90 100 110 120
pF1KB3 LGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAM
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB3 KVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB3 GHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB3 RRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB3 IEELEREAERKIIEENITSAAPSNDQDGEYCPEVKLKTTGLEEAAEAETAKDNGEAEDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEELEREAERKIIEENITSAAPSNDQDGEYCPEVKLKTTGLEEAAEAETAKDNGEAEDQE
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB3 EKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLEQQLDDEDDDEEDCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLEQQLDDEDDDEEDCP
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB3 NPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGSLEPVACGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGSLEPVACGS
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB3 VLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKAKTRAADLLVNPLDPRNADKIRVKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKAKTRAADLLVNPLDPRNADKIRVKIA
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB3 DLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSG
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB3 EDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKY
::::::::::: ::::::..::..:. ::::.:::.:.::::::::::::::::::::::
XP_016 EDYSRDEDHIALIIELLGKVPRKYAMLGKYSKEFFTRKGELRHITKLKPWSLFDVLVEKY
590 600 610 620 630 640
670 680 690
pF1KB3 GWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS
:::::::::::::::::::::::::::::::::::::::
XP_016 GWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS
650 660 670 680
>>XP_005250607 (OMIM: 602980) PREDICTED: SRSF protein ki (730 aa)
initn: 4504 init1: 4368 opt: 4373 Z-score: 1987.3 bits: 378.3 E(85289): 5.9e-104
Smith-Waterman score: 4732; 95.8% identity (95.8% similar) in 730 aa overlap (1-699:1-730)
10 20 30 40 50 60
pF1KB3 MSSRKVLAIQARKRRPKREKHPKKPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSRKVLAIQARKRRPKREKHPKKPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 IEELEREAERKIIEENITSAAPSNDQDGEYCPEVKLKTTGLEEAAEAETAKDNGEAEDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEELEREAERKIIEENITSAAPSNDQDGEYCPEVKLKTTGLEEAAEAETAKDNGEAEDQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLEQQLDDEDDDEEDCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLEQQLDDEDDDEEDCP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 NPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGSLEPVACGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGSLEPVACGS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 VLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKAKTRAADLLVNPLDPRNADKIRVKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKAKTRAADLLVNPLDPRNADKIRVKIA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 DLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSG
550 560 570 580 590 600
610 620 630
pF1KB3 EDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRR----------------------
::::::::::::::::::::::::::::::::::::::
XP_005 EDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRDHIALIIELLGKVPRKYAMLGK
610 620 630 640 650 660
640 650 660 670 680
pF1KB3 ---------GELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAG
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSKEFFTRKGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAG
670 680 690 700 710 720
690
pF1KB3 ECLRHPWLNS
::::::::::
XP_005 ECLRHPWLNS
730
>>XP_005250606 (OMIM: 602980) PREDICTED: SRSF protein ki (811 aa)
initn: 4583 init1: 4338 opt: 4346 Z-score: 1974.6 bits: 376.1 E(85289): 3e-103
Smith-Waterman score: 4705; 95.6% identity (95.7% similar) in 726 aa overlap (5-699:86-811)
10 20 30
pF1KB3 MSSRKVLAIQARKRRPKREKHPKKPEPQQKAPLV
.:::::::::::::::::::::::::::::
XP_005 EKRPREERWCETRGGAGQGRAHGAAGGATGRVLAIQARKRRPKREKHPKKPEPQQKAPLV
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB3 PPPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHV
120 130 140 150 160 170
100 110 120 130 140 150
pF1KB3 IRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPNKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPNKD
180 190 200 210 220 230
160 170 180 190 200 210
pF1KB3 MVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDY
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB3 LHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGK
300 310 320 330 340 350
280 290 300 310 320 330
pF1KB3 ISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKIIEENITSAAPSNDQDGEYCPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKIIEENITSAAPSNDQDGEYCPEV
360 370 380 390 400 410
340 350 360 370 380 390
pF1KB3 KLKTTGLEEAAEAETAKDNGEAEDQEEKEDAEKENIEKDEDDVDQELANIDPTWIESPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLKTTGLEEAAEAETAKDNGEAEDQEEKEDAEKENIEKDEDDVDQELANIDPTWIESPKT
420 430 440 450 460 470
400 410 420 430 440 450
pF1KB3 NGHIENGPFSLEQQLDDEDDDEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGHIENGPFSLEQQLDDEDDDEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRH
480 490 500 510 520 530
460 470 480 490 500 510
pF1KB3 KIPESQFPEFSTSLFSGSLEPVACGSVLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIPESQFPEFSTSLFSGSLEPVACGSVLSEGSPLTEQEESSPSHDRSRTVSASSTGDLPK
540 550 560 570 580 590
520 530 540 550 560 570
pF1KB3 AKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYST
600 610 620 630 640 650
580 590 600 610 620 630
pF1KB3 PADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREF
660 670 680 690 700 710
640 650 660
pF1KB3 FNRR-------------------------------GELRHITKLKPWSLFDVLVEKYGWP
:::: :::::::::::::::::::::::::
XP_005 FNRRDHIALIIELLGKVPRKYAMLGKYSKEFFTRKGELRHITKLKPWSLFDVLVEKYGWP
720 730 740 750 760 770
670 680 690
pF1KB3 HEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS
::::::::::::::::::::::::::::::::::::
XP_005 HEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS
780 790 800 810
699 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 01:51:42 2016 done: Sat Nov 5 01:51:44 2016
Total Scan time: 13.210 Total Display time: 0.180
Function used was FASTA [36.3.4 Apr, 2011]