FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3392, 346 aa 1>>>pF1KB3392 346 - 346 aa - 346 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4509+/-0.000413; mu= 16.0656+/- 0.026 mean_var=77.1036+/-14.916, 0's: 0 Z-trim(111.7): 62 B-trim: 0 in 0/54 Lambda= 0.146062 statistics sampled from 20258 (20320) to 20258 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.603), E-opt: 0.2 (0.238), width: 16 Scan time: 6.880 The best scores are: opt bits E(85289) NP_000691 (OMIM: 151690) annexin A1 [Homo sapiens] ( 346) 2207 474.7 1.3e-133 XP_011516911 (OMIM: 151690) PREDICTED: annexin A1 ( 346) 2207 474.7 1.3e-133 XP_016870146 (OMIM: 151690) PREDICTED: annexin A1 ( 357) 2207 474.7 1.3e-133 NP_001002857 (OMIM: 151740) annexin A2 isoform 2 [ ( 339) 1106 242.7 8.6e-64 XP_016877580 (OMIM: 151740) PREDICTED: annexin A2 ( 339) 1106 242.7 8.6e-64 NP_004030 (OMIM: 151740) annexin A2 isoform 2 [Hom ( 339) 1106 242.7 8.6e-64 XP_016877579 (OMIM: 151740) PREDICTED: annexin A2 ( 339) 1106 242.7 8.6e-64 NP_001129487 (OMIM: 151740) annexin A2 isoform 2 [ ( 339) 1106 242.7 8.6e-64 NP_001002858 (OMIM: 151740) annexin A2 isoform 1 [ ( 357) 1106 242.7 8.9e-64 NP_005130 (OMIM: 106490) annexin A3 [Homo sapiens] ( 323) 985 217.2 3.9e-56 NP_001265338 (OMIM: 602572) annexin A11 isoform 2 ( 472) 983 216.9 7.1e-56 XP_011538038 (OMIM: 602572) PREDICTED: annexin A11 ( 505) 983 216.9 7.5e-56 NP_665876 (OMIM: 602572) annexin A11 isoform 1 [Ho ( 505) 983 216.9 7.5e-56 NP_001265337 (OMIM: 602572) annexin A11 isoform 1 ( 505) 983 216.9 7.5e-56 NP_665875 (OMIM: 602572) annexin A11 isoform 1 [Ho ( 505) 983 216.9 7.5e-56 NP_001265336 (OMIM: 602572) annexin A11 isoform 1 ( 505) 983 216.9 7.5e-56 NP_001148 (OMIM: 602572) annexin A11 isoform 1 [Ho ( 505) 983 216.9 7.5e-56 XP_005269798 (OMIM: 602572) PREDICTED: annexin A11 ( 605) 983 217.0 8.6e-56 NP_001307808 (OMIM: 186360) annexin A7 isoform 4 [ ( 426) 921 203.8 5.6e-52 NP_001307809 (OMIM: 186360) annexin A7 isoform 3 [ ( 448) 921 203.8 5.8e-52 NP_001147 (OMIM: 186360) annexin A7 isoform 1 [Hom ( 466) 921 203.8 6e-52 XP_016871652 (OMIM: 186360) PREDICTED: annexin A7 ( 466) 921 203.8 6e-52 NP_004025 (OMIM: 186360) annexin A7 isoform 2 [Hom ( 488) 921 203.8 6.2e-52 XP_016871651 (OMIM: 186360) PREDICTED: annexin A7 ( 488) 921 203.8 6.2e-52 XP_011538037 (OMIM: 602572) PREDICTED: annexin A11 ( 542) 902 199.9 1.1e-50 XP_006717877 (OMIM: 602572) PREDICTED: annexin A11 ( 542) 902 199.9 1.1e-50 XP_005269799 (OMIM: 602572) PREDICTED: annexin A11 ( 542) 902 199.9 1.1e-50 XP_006717876 (OMIM: 602572) PREDICTED: annexin A11 ( 542) 902 199.9 1.1e-50 NP_001144 (OMIM: 106491) annexin A4 isoform a [Hom ( 321) 894 198.0 2.3e-50 NP_001307627 (OMIM: 106491) annexin A4 isoform a [ ( 321) 894 198.0 2.3e-50 XP_016859432 (OMIM: 106491) PREDICTED: annexin A4 ( 321) 894 198.0 2.3e-50 XP_005268489 (OMIM: 114070) PREDICTED: annexin A6 ( 667) 873 193.8 8.9e-49 NP_001146 (OMIM: 114070) annexin A6 isoform 1 [Hom ( 673) 873 193.8 8.9e-49 NP_001035173 (OMIM: 602396) annexin A8 isoform 2 [ ( 327) 855 189.8 7e-48 XP_006718014 (OMIM: 602396) PREDICTED: annexin A8 ( 351) 855 189.8 7.4e-48 NP_001003954 (OMIM: 602573) annexin A13 isoform b ( 357) 855 189.8 7.5e-48 XP_011538398 (OMIM: 602396) PREDICTED: annexin A8 ( 448) 855 189.9 8.9e-48 NP_001145 (OMIM: 131230,614391) annexin A5 [Homo s ( 320) 849 188.6 1.6e-47 NP_004297 (OMIM: 602573) annexin A13 isoform a [Ho ( 316) 845 187.7 2.9e-47 NP_001180473 (OMIM: 114070) annexin A6 isoform 2 [ ( 641) 821 182.9 1.7e-45 NP_001258631 (OMIM: 602396) annexin A8 isoform 1 [ ( 365) 808 180.0 7.3e-45 XP_016877582 (OMIM: 151740) PREDICTED: annexin A2 ( 222) 797 177.5 2.4e-44 XP_016877581 (OMIM: 151740) PREDICTED: annexin A2 ( 222) 797 177.5 2.4e-44 XP_011519779 (OMIM: 151740) PREDICTED: annexin A2 ( 222) 797 177.5 2.4e-44 NP_009124 (OMIM: 608008) annexin A10 [Homo sapiens ( 324) 749 167.5 3.7e-41 NP_001307631 (OMIM: 106491) annexin A4 isoform c [ ( 237) 704 157.9 2e-38 XP_016859433 (OMIM: 106491) PREDICTED: annexin A4 ( 237) 704 157.9 2e-38 NP_001258632 (OMIM: 602396) annexin A8 isoform 3 [ ( 265) 695 156.0 8.3e-38 NP_003559 (OMIM: 603319) annexin A9 [Homo sapiens] ( 345) 677 152.3 1.4e-36 NP_001307629 (OMIM: 106491) annexin A4 isoform b [ ( 299) 664 149.5 8.5e-36 >>NP_000691 (OMIM: 151690) annexin A1 [Homo sapiens] (346 aa) initn: 2207 init1: 2207 opt: 2207 Z-score: 2520.0 bits: 474.7 E(85289): 1.3e-133 Smith-Waterman score: 2207; 100.0% identity (100.0% similar) in 346 aa overlap (1-346:1-346) 10 20 30 40 50 60 pF1KB3 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 DELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIM 250 260 270 280 290 300 310 320 330 340 pF1KB3 VSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN :::::::::::::::::::::::::::::::::::::::::::::: NP_000 VSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 310 320 330 340 >>XP_011516911 (OMIM: 151690) PREDICTED: annexin A1 isof (346 aa) initn: 2207 init1: 2207 opt: 2207 Z-score: 2520.0 bits: 474.7 E(85289): 1.3e-133 Smith-Waterman score: 2207; 100.0% identity (100.0% similar) in 346 aa overlap (1-346:1-346) 10 20 30 40 50 60 pF1KB3 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 DELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIM 250 260 270 280 290 300 310 320 330 340 pF1KB3 VSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN :::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 310 320 330 340 >>XP_016870146 (OMIM: 151690) PREDICTED: annexin A1 isof (357 aa) initn: 2207 init1: 2207 opt: 2207 Z-score: 2519.8 bits: 474.7 E(85289): 1.3e-133 Smith-Waterman score: 2207; 100.0% identity (100.0% similar) in 346 aa overlap (1-346:12-357) 10 20 30 40 pF1KB3 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVA ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNLILRYTFSKMAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB3 ALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB3 ALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDIT 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB3 SDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRS 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB3 YPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGV 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB3 GTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 310 320 330 340 350 >>NP_001002857 (OMIM: 151740) annexin A2 isoform 2 [Homo (339 aa) initn: 1249 init1: 578 opt: 1106 Z-score: 1266.3 bits: 242.7 E(85289): 8.6e-64 Smith-Waterman score: 1106; 53.5% identity (79.8% similar) in 327 aa overlap (24-346:12-338) 10 20 30 40 50 pF1KB3 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSA---VSPYPTFNPSSDVAALHKAIMV ....... : :: :. : .:. :. .. :: . NP_001 MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKT 10 20 30 40 60 70 80 90 100 110 pF1KB3 KGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQ :::::.::..:::.:.:::::.: :: ..: : : .::.::.:::: :.:.::::::: NP_001 KGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQ 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB3 FDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFR .::.::.:.:::::::::.::::. ::::.:...:::::.: : :: ::: :::::::: NP_001 YDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFR 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB3 NALLSLAKGDRSEDFGV-NEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRV . ...:::: :.:: .: . .: :.::: ::.:: .:::::: . .:.: :: :.:..: NP_001 KLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKV 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB3 FQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKAL :..: .:: .:: . . :.:::.:. . .:.: .:: .::..:...::: ::: :.: NP_001 FDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVL 230 240 250 260 270 280 300 310 320 330 340 pF1KB3 IRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN :::::::::.:: :.. ... :: :: : ..:::::.: :. ::::. NP_001 IRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD 290 300 310 320 330 >>XP_016877580 (OMIM: 151740) PREDICTED: annexin A2 isof (339 aa) initn: 1249 init1: 578 opt: 1106 Z-score: 1266.3 bits: 242.7 E(85289): 8.6e-64 Smith-Waterman score: 1106; 53.5% identity (79.8% similar) in 327 aa overlap (24-346:12-338) 10 20 30 40 50 pF1KB3 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSA---VSPYPTFNPSSDVAALHKAIMV ....... : :: :. : .:. :. .. :: . XP_016 MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKT 10 20 30 40 60 70 80 90 100 110 pF1KB3 KGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQ :::::.::..:::.:.:::::.: :: ..: : : .::.::.:::: :.:.::::::: XP_016 KGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQ 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB3 FDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFR .::.::.:.:::::::::.::::. ::::.:...:::::.: : :: ::: :::::::: XP_016 YDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFR 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB3 NALLSLAKGDRSEDFGV-NEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRV . ...:::: :.:: .: . .: :.::: ::.:: .:::::: . .:.: :: :.:..: XP_016 KLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKV 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB3 FQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKAL :..: .:: .:: . . :.:::.:. . .:.: .:: .::..:...::: ::: :.: XP_016 FDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVL 230 240 250 260 270 280 300 310 320 330 340 pF1KB3 IRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN :::::::::.:: :.. ... :: :: : ..:::::.: :. ::::. XP_016 IRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD 290 300 310 320 330 >>NP_004030 (OMIM: 151740) annexin A2 isoform 2 [Homo sa (339 aa) initn: 1249 init1: 578 opt: 1106 Z-score: 1266.3 bits: 242.7 E(85289): 8.6e-64 Smith-Waterman score: 1106; 53.5% identity (79.8% similar) in 327 aa overlap (24-346:12-338) 10 20 30 40 50 pF1KB3 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSA---VSPYPTFNPSSDVAALHKAIMV ....... : :: :. : .:. :. .. :: . NP_004 MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKT 10 20 30 40 60 70 80 90 100 110 pF1KB3 KGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQ :::::.::..:::.:.:::::.: :: ..: : : .::.::.:::: :.:.::::::: NP_004 KGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQ 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB3 FDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFR .::.::.:.:::::::::.::::. ::::.:...:::::.: : :: ::: :::::::: NP_004 YDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFR 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB3 NALLSLAKGDRSEDFGV-NEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRV . ...:::: :.:: .: . .: :.::: ::.:: .:::::: . .:.: :: :.:..: NP_004 KLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKV 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB3 FQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKAL :..: .:: .:: . . :.:::.:. . .:.: .:: .::..:...::: ::: :.: NP_004 FDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVL 230 240 250 260 270 280 300 310 320 330 340 pF1KB3 IRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN :::::::::.:: :.. ... :: :: : ..:::::.: :. ::::. NP_004 IRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD 290 300 310 320 330 >>XP_016877579 (OMIM: 151740) PREDICTED: annexin A2 isof (339 aa) initn: 1249 init1: 578 opt: 1106 Z-score: 1266.3 bits: 242.7 E(85289): 8.6e-64 Smith-Waterman score: 1106; 53.5% identity (79.8% similar) in 327 aa overlap (24-346:12-338) 10 20 30 40 50 pF1KB3 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSA---VSPYPTFNPSSDVAALHKAIMV ....... : :: :. : .:. :. .. :: . XP_016 MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKT 10 20 30 40 60 70 80 90 100 110 pF1KB3 KGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQ :::::.::..:::.:.:::::.: :: ..: : : .::.::.:::: :.:.::::::: XP_016 KGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQ 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB3 FDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFR .::.::.:.:::::::::.::::. ::::.:...:::::.: : :: ::: :::::::: XP_016 YDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFR 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB3 NALLSLAKGDRSEDFGV-NEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRV . ...:::: :.:: .: . .: :.::: ::.:: .:::::: . .:.: :: :.:..: XP_016 KLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKV 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB3 FQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKAL :..: .:: .:: . . :.:::.:. . .:.: .:: .::..:...::: ::: :.: XP_016 FDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVL 230 240 250 260 270 280 300 310 320 330 340 pF1KB3 IRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN :::::::::.:: :.. ... :: :: : ..:::::.: :. ::::. XP_016 IRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD 290 300 310 320 330 >>NP_001129487 (OMIM: 151740) annexin A2 isoform 2 [Homo (339 aa) initn: 1249 init1: 578 opt: 1106 Z-score: 1266.3 bits: 242.7 E(85289): 8.6e-64 Smith-Waterman score: 1106; 53.5% identity (79.8% similar) in 327 aa overlap (24-346:12-338) 10 20 30 40 50 pF1KB3 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSA---VSPYPTFNPSSDVAALHKAIMV ....... : :: :. : .:. :. .. :: . NP_001 MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKT 10 20 30 40 60 70 80 90 100 110 pF1KB3 KGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQ :::::.::..:::.:.:::::.: :: ..: : : .::.::.:::: :.:.::::::: NP_001 KGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQ 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB3 FDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFR .::.::.:.:::::::::.::::. ::::.:...:::::.: : :: ::: :::::::: NP_001 YDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFR 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB3 NALLSLAKGDRSEDFGV-NEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRV . ...:::: :.:: .: . .: :.::: ::.:: .:::::: . .:.: :: :.:..: NP_001 KLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKV 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB3 FQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKAL :..: .:: .:: . . :.:::.:. . .:.: .:: .::..:...::: ::: :.: NP_001 FDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVL 230 240 250 260 270 280 300 310 320 330 340 pF1KB3 IRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN :::::::::.:: :.. ... :: :: : ..:::::.: :. ::::. NP_001 IRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD 290 300 310 320 330 >>NP_001002858 (OMIM: 151740) annexin A2 isoform 1 [Homo (357 aa) initn: 1249 init1: 578 opt: 1106 Z-score: 1266.0 bits: 242.7 E(85289): 8.9e-64 Smith-Waterman score: 1106; 53.5% identity (79.8% similar) in 327 aa overlap (24-346:30-356) 10 20 30 40 50 pF1KB3 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSA---VSPYPTFNPSSDVAAL ....... : :: :. : .:. :. . NP_001 MGRQLAGCGDAGKKASFKMSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 HKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLAL . :: .:::::.::..:::.:.:::::.: :: ..: : : .::.::.:::: :.:.: NP_001 ETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVILGL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 LKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSD ::::::.::.::.:.:::::::::.::::. ::::.:...:::::.: : :: ::: :: NP_001 LKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 TSGDFRNALLSLAKGDRSEDFGV-NEDLADSDARALYEAGERRKGTDVNVFNTILTTRSY ::::::. ...:::: :.:: .: . .: :.::: ::.:: .:::::: . .:.: :: NP_001 TSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 PQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVG :.:..::..: .:: .:: . . :.:::.:. . .:.: .:: .::..:...::: : NP_001 PHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKG 250 260 270 280 290 300 300 310 320 330 340 pF1KB3 TRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN :: :.::::::::::.:: :.. ... :: :: : ..:::::.: :. ::::. NP_001 TRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD 310 320 330 340 350 >>NP_005130 (OMIM: 106490) annexin A3 [Homo sapiens] (323 aa) initn: 1322 init1: 979 opt: 985 Z-score: 1128.8 bits: 217.2 E(85289): 3.9e-56 Smith-Waterman score: 985; 49.7% identity (76.3% similar) in 316 aa overlap (31-346:7-322) 10 20 30 40 50 60 pF1KB3 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGV : ..: :: :.:: :. :..::: :. NP_005 MASIWVGHRGTVRDYPDFSPSVDAEAIQKAIRGIGT 10 20 30 70 80 90 100 110 120 pF1KB3 DEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDA :: .:.:::.:.::::: : : :: : . :: :.::.:....::. :: ::: NP_005 DEKMLISILTERSNAQRQLIVKEYQAAYGKELKDDLKGDLSGHFEHLMVALVTPPAVFDA 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB3 DELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNAL .:. .::: ::.::.:::::..::.....::...: :..:. ::.:.::::::.:: NP_005 KQLKKSMKGAGTNEDALIEILTTRTSRQMKDISQAYYTVYKKSLGDDISSETSGDFRKAL 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB3 LSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKY :.:: : :.:.. :.: :: .::. ::.::: : ::: . :. :: ::.:::. .:..: NP_005 LTLADGRRDESLKVDEHLAKQDAQILYKAGENRWGTDEDKFTEILCLRSFPQLKLTFDEY 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB3 TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIM . :..:. . ::.: .: : :::.:. . :::.::.::.:.::.:: . .: ::: NP_005 RNISQKDIVDSIKGELSGHFEDLLLAIVNCVRNTPAFLAERLHRALKGIGTDEFTLNRIM 220 230 240 250 260 270 310 320 330 340 pF1KB3 VSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN :::::::. ::.. ..: :: :: .:: ..:.:::: :. .:::. NP_005 VSRSEIDLLDIRTEFKKHYGYSLYSAIKSDTSGDYEITLLKICGGDD 280 290 300 310 320 346 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:56:53 2016 done: Sat Nov 5 04:56:54 2016 Total Scan time: 6.880 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]