FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3399, 186 aa 1>>>pF1KB3399 186 - 186 aa - 186 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.2629+/-0.000416; mu= 18.6094+/- 0.026 mean_var=57.8875+/-11.782, 0's: 0 Z-trim(110.1): 8 B-trim: 0 in 0/51 Lambda= 0.168571 statistics sampled from 18362 (18368) to 18362 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.587), E-opt: 0.2 (0.215), width: 16 Scan time: 5.060 The best scores are: opt bits E(85289) NP_004856 (OMIM: 605521) TATA box-binding protein- ( 186) 1201 300.3 1.2e-81 NP_001240605 (OMIM: 605521) TATA box-binding prote ( 186) 1201 300.3 1.2e-81 XP_016867002 (OMIM: 605521) PREDICTED: TATA box-bi ( 186) 1201 300.3 1.2e-81 NP_001165556 (OMIM: 168600,600075,607136) TATA-box ( 319) 460 120.3 3.2e-27 NP_003185 (OMIM: 168600,600075,607136) TATA-box-bi ( 339) 460 120.3 3.3e-27 NP_950248 (OMIM: 608964) TATA box-binding protein- ( 375) 451 118.1 1.6e-26 >>NP_004856 (OMIM: 605521) TATA box-binding protein-like (186 aa) initn: 1201 init1: 1201 opt: 1201 Z-score: 1586.8 bits: 300.3 E(85289): 1.2e-81 Smith-Waterman score: 1201; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186) 10 20 30 40 50 60 pF1KB3 MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 WSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 WSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFE 130 140 150 160 170 180 pF1KB3 SRKEIL :::::: NP_004 SRKEIL >>NP_001240605 (OMIM: 605521) TATA box-binding protein-l (186 aa) initn: 1201 init1: 1201 opt: 1201 Z-score: 1586.8 bits: 300.3 E(85289): 1.2e-81 Smith-Waterman score: 1201; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186) 10 20 30 40 50 60 pF1KB3 MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 WSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFE 130 140 150 160 170 180 pF1KB3 SRKEIL :::::: NP_001 SRKEIL >>XP_016867002 (OMIM: 605521) PREDICTED: TATA box-bindin (186 aa) initn: 1201 init1: 1201 opt: 1201 Z-score: 1586.8 bits: 300.3 E(85289): 1.2e-81 Smith-Waterman score: 1201; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186) 10 20 30 40 50 60 pF1KB3 MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 WSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 TKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFE 130 140 150 160 170 180 pF1KB3 SRKEIL :::::: XP_016 SRKEIL >>NP_001165556 (OMIM: 168600,600075,607136) TATA-box-bin (319 aa) initn: 437 init1: 359 opt: 460 Z-score: 609.8 bits: 120.3 E(85289): 3.2e-27 Smith-Waterman score: 460; 42.2% identity (74.0% similar) in 173 aa overlap (13-183:145-317) 10 20 30 40 pF1KB3 MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYK- . :.: . :.:.:. :::.. :. :. NP_001 TTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNP 120 130 140 150 160 170 50 60 70 80 90 100 pF1KB3 RDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFK . . :.:..:.:: :: :.::::..:::: :::.....::. :: .::::: . : ::: NP_001 KRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFK 180 190 200 210 220 230 110 120 130 140 150 160 pF1KB3 VVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTG . :... :.. : ::: .. ... .:::::: :.. ::. . : .: :: .:....:: NP_001 IQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTG 240 250 260 270 280 290 170 180 pF1KB3 PNVKA-VATAVEQIYPFVFESRKEIL .:.: . : :.:::.. :: NP_001 AKVRAEIYEAFENIYPILKGFRKTT 300 310 >>NP_003185 (OMIM: 168600,600075,607136) TATA-box-bindin (339 aa) initn: 437 init1: 359 opt: 460 Z-score: 609.5 bits: 120.3 E(85289): 3.3e-27 Smith-Waterman score: 460; 42.2% identity (74.0% similar) in 173 aa overlap (13-183:165-337) 10 20 30 40 pF1KB3 MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYK- . :.: . :.:.:. :::.. :. :. NP_003 TTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNP 140 150 160 170 180 190 50 60 70 80 90 100 pF1KB3 RDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFK . . :.:..:.:: :: :.::::..:::: :::.....::. :: .::::: . : ::: NP_003 KRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFK 200 210 220 230 240 250 110 120 130 140 150 160 pF1KB3 VVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTG . :... :.. : ::: .. ... .:::::: :.. ::. . : .: :: .:....:: NP_003 IQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTG 260 270 280 290 300 310 170 180 pF1KB3 PNVKA-VATAVEQIYPFVFESRKEIL .:.: . : :.:::.. :: NP_003 AKVRAEIYEAFENIYPILKGFRKTT 320 330 >>NP_950248 (OMIM: 608964) TATA box-binding protein-like (375 aa) initn: 371 init1: 371 opt: 451 Z-score: 597.1 bits: 118.1 E(85289): 1.6e-26 Smith-Waterman score: 451; 41.7% identity (75.0% similar) in 168 aa overlap (13-178:202-369) 10 20 30 40 pF1KB3 MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYK- . :.: . :.:.:.::::.. :. :. NP_950 KPNSDSLSLASITPMTPMTPISECCGIVPQLQNIVSTVNLACKLDLKKIALHAKNAEYNP 180 190 200 210 220 230 50 60 70 80 90 100 pF1KB3 RDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFK . . :.:..:.:: :: :.::::..:::: :::.....::. :: .::::: . : ::: NP_950 KRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPARFLDFK 240 250 260 270 280 290 110 120 130 140 150 160 pF1KB3 VVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTG . :... :.. : ::: .. ... .:::::: :.. ::. . : .: :: .:....:: NP_950 IQNMVGSCDVRFPIRLEGLVLTHQQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTG 300 310 320 330 340 350 170 180 pF1KB3 PNVKA-VATAVEQIYPFVFESRKEIL . .. . : :.:::.. NP_950 AKERSEIYEAFENIYPILKGFKKA 360 370 186 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:18:26 2016 done: Fri Nov 4 02:18:27 2016 Total Scan time: 5.060 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]