FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3406, 367 aa 1>>>pF1KB3406 367 - 367 aa - 367 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0980+/-0.000832; mu= 12.9663+/- 0.050 mean_var=78.1007+/-15.590, 0's: 0 Z-trim(107.9): 17 B-trim: 0 in 0/49 Lambda= 0.145127 statistics sampled from 9825 (9839) to 9825 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.302), width: 16 Scan time: 2.850 The best scores are: opt bits E(32554) CCDS13897.1 DRG1 gene_id:4733|Hs108|chr22 ( 367) 2399 511.6 4.2e-145 CCDS11191.1 DRG2 gene_id:1819|Hs108|chr17 ( 364) 1351 292.2 4.7e-79 CCDS82082.1 DRG2 gene_id:1819|Hs108|chr17 ( 343) 1187 257.9 9.8e-69 >>CCDS13897.1 DRG1 gene_id:4733|Hs108|chr22 (367 aa) initn: 2399 init1: 2399 opt: 2399 Z-score: 2718.5 bits: 511.6 E(32554): 4.2e-145 Smith-Waterman score: 2399; 100.0% identity (100.0% similar) in 367 aa overlap (1-367:1-367) 10 20 30 40 50 60 pF1KB3 MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 KTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 IIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 IIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 FKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 FKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 IPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 IPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 QLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 QLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDED 310 320 330 340 350 360 pF1KB3 VIQIVKK ::::::: CCDS13 VIQIVKK >>CCDS11191.1 DRG2 gene_id:1819|Hs108|chr17 (364 aa) initn: 1375 init1: 974 opt: 1351 Z-score: 1532.7 bits: 292.2 E(32554): 4.7e-79 Smith-Waterman score: 1351; 57.6% identity (81.5% similar) in 363 aa overlap (5-367:4-364) 10 20 30 40 50 60 pF1KB3 MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVA : ::.::: :.::::::::: .:::::::.::: : .:. :. .... :::::: CCDS11 MGILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSASS-KGEGFDVM 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 KTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPG :.::::....:::::::::.:: .... ::.:.::::::: .::::.::::.:::::::: CCDS11 KSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPG 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 IIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIG ::::: .:::::::::::::: ..:...::. : .....:.:::. :::::.. ::: CCDS11 IIEGAAQGKGRGRQVIAVARTADVIIMMLDATKGEVQRSLLEKELESVGIRLNKHKPNIY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 FKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVY :: : :::....: .. . . :. :: :::: ::.: .: : . :..:::. ::::: CCDS11 FKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRVY 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 IPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKG .::.:: :::::::.::.: . . :. : :: . :.: ::: .:.:: :. :::: .: CCDS11 MPCLYVYNKIDQISMEEVDRLARKPNSVVISCGMKLNLDYLLEMLWEYLALTCIYTKKRG 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB3 QLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDED : ::.:. ..: . ..:: : .::..: ..:::::::: :.:..::.:: ::.: :: CCDS11 QRPDFTDAIIL-RKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHTMEHED 300 310 320 330 340 350 pF1KB3 VIQIVKK ::::::: CCDS11 VIQIVKK 360 >>CCDS82082.1 DRG2 gene_id:1819|Hs108|chr17 (343 aa) initn: 1211 init1: 974 opt: 1187 Z-score: 1347.5 bits: 257.9 E(32554): 9.8e-69 Smith-Waterman score: 1187; 56.1% identity (80.9% similar) in 330 aa overlap (5-334:4-331) 10 20 30 40 50 60 pF1KB3 MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVA : ::.::: :.::::::::: .:::::::.::: : .:. :. .... :::::: CCDS82 MGILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSASS-KGEGFDVM 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 KTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPG :.::::....:::::::::.:: .... ::.:.::::::: .::::.::::.:::::::: CCDS82 KSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPG 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 IIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIG ::::: .:::::::::::::: ..:...::. : .....:.:::. :::::.. ::: CCDS82 IIEGAAQGKGRGRQVIAVARTADVIIMMLDATKGEVQRSLLEKELESVGIRLNKHKPNIY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 FKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVY :: : :::....: .. . . :. :: :::: ::.: .: : . :..:::. ::::: CCDS82 FKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRVY 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 IPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKG .::.:: :::::::.::.: . . :. : :: . :.: ::: .:.:: :. :::: .: CCDS82 MPCLYVYNKIDQISMEEVDRLARKPNSVVISCGMKLNLDYLLEMLWEYLALTCIYTKKRG 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB3 QLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDED : ::.:. ..: . ..:: : .::..: ..:: CCDS82 QRPDFTDAIIL-RKGASVEHVCHRIHRSLASQFKAPAPSTVRSGWA 300 310 320 330 340 pF1KB3 VIQIVKK 367 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:20:22 2016 done: Fri Nov 4 02:20:22 2016 Total Scan time: 2.850 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]