FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3413, 339 aa 1>>>pF1KB3413 339 - 339 aa - 339 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1023+/-0.00107; mu= 6.2836+/- 0.062 mean_var=136.3043+/-29.255, 0's: 0 Z-trim(108.3): 151 B-trim: 396 in 1/49 Lambda= 0.109855 statistics sampled from 9941 (10137) to 9941 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.311), width: 16 Scan time: 2.680 The best scores are: opt bits E(32554) CCDS2019.1 CIAO1 gene_id:9391|Hs108|chr2 ( 339) 2444 399.1 2.7e-111 CCDS46961.1 TBL1XR1 gene_id:79718|Hs108|chr3 ( 514) 398 75.0 1.5e-13 CCDS14779.1 TBL1Y gene_id:90665|Hs108|chrY ( 522) 373 71.0 2.4e-12 CCDS48078.1 TBL1X gene_id:6907|Hs108|chrX ( 526) 369 70.4 3.7e-12 CCDS14133.1 TBL1X gene_id:6907|Hs108|chrX ( 577) 369 70.4 4e-12 CCDS32528.1 PAFAH1B1 gene_id:5048|Hs108|chr17 ( 410) 342 66.0 6e-11 >>CCDS2019.1 CIAO1 gene_id:9391|Hs108|chr2 (339 aa) initn: 2444 init1: 2444 opt: 2444 Z-score: 2111.6 bits: 399.1 E(32554): 2.7e-111 Smith-Waterman score: 2444; 100.0% identity (100.0% similar) in 339 aa overlap (1-339:1-339) 10 20 30 40 50 60 pF1KB3 MKDSLVLLGRVPAHPDSRCWFLAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 MKDSLVLLGRVPAHPDSRCWFLAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 QRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 QRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 ATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 ATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 EDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 EDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 WKCICTLSGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDPQQPTFSLTAHLHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 WKCICTLSGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDPQQPTFSLTAHLHQ 250 260 270 280 290 300 310 320 330 pF1KB3 AHSQDVNCVAWNPKEPGLLASCSDDGEVAFWKYQRPEGL ::::::::::::::::::::::::::::::::::::::: CCDS20 AHSQDVNCVAWNPKEPGLLASCSDDGEVAFWKYQRPEGL 310 320 330 >>CCDS46961.1 TBL1XR1 gene_id:79718|Hs108|chr3 (514 aa) initn: 276 init1: 156 opt: 398 Z-score: 356.6 bits: 75.0 E(32554): 1.5e-13 Smith-Waterman score: 408; 32.8% identity (54.1% similar) in 259 aa overlap (11-221:222-469) 10 20 30 40 pF1KB3 MKDSLVLLGRVPAHPDSRCWFLAWNPAGTLLASCGGDRRI ::.. : : :: :::::. . : CCDS46 TARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTS--LDWNSEGTLLATGSYDGFA 200 210 220 230 240 50 60 70 80 90 pF1KB3 RIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWK------KNQDD ::: .:. :.:.. :. . . :. ::.. ::. : :: :: :.: CCDS46 RIWTKDGN---LASTLGQ-HKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFP 250 260 270 280 290 300 100 110 120 pF1KB3 FE-----------------CVT----------------TLEGHENEVKSVAWAPSGNLLA :. : : :..:: :::... : :.::::: CCDS46 FHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLA 310 320 330 340 350 360 130 140 150 160 170 pF1KB3 TCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQE---------LLASASYDD .:: : .. .: . ... :: :..:.... . : :. .:::::.:. CCDS46 SCSDDMTLKIWSMKQDN---CVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDS 370 380 390 400 410 420 180 190 200 210 220 230 pF1KB3 TVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIWRQYLPGNEQGV ::.:. . : .: :: :. :.:.::.:.:. ::: : :. :.:: CCDS46 TVRLW--DVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY 430 440 450 460 470 480 240 250 260 270 280 290 pF1KB3 ACSGSDPSWKCICTLSGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDPQQPTF CCDS46 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 490 500 510 >>CCDS14779.1 TBL1Y gene_id:90665|Hs108|chrY (522 aa) initn: 348 init1: 146 opt: 373 Z-score: 335.1 bits: 71.0 E(32554): 2.4e-12 Smith-Waterman score: 401; 34.0% identity (53.3% similar) in 259 aa overlap (11-221:232-479) 10 20 30 40 pF1KB3 MKDSLVLLGRVPAHPDSRCWFLAWNPAGTLLASCGGDRRI ::.. : : :: ::::: . : CCDS14 TARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTS--LDWNSDGTLLAMGSYDGFA 210 220 230 240 250 50 60 70 80 90 pF1KB3 RIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWK------KNQDD ::: .:. :.:.. :. . . :. :::. ::. : :: :: :.: CCDS14 RIWTENGN---LASTLGQ-HKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFP 260 270 280 290 300 310 100 110 120 pF1KB3 FE-----------------C----------------VTTLEGHENEVKSVAWAPSGNLLA :. : : :..:: :::... : ::: ::: CCDS14 FHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLA 320 330 340 350 360 370 130 140 150 160 170 pF1KB3 TCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHP---------SQELLASASYDD .:: : .. .: . .. :: :..:.... . : : :. .:::::.:. CCDS14 SCSDDMTLKIWSMKQD---ACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDS 380 390 400 410 420 430 180 190 200 210 220 230 pF1KB3 TVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIWRQYLPGNEQGV ::.:. :. :: :: :. :.:.::.:.:. ::: : :. :.:: CCDS14 TVRLWDVEQG--VCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSY 440 450 460 470 480 490 240 250 260 270 280 290 pF1KB3 ACSGSDPSWKCICTLSGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDPQQPTF CCDS14 QGTGGIFEVCWNARGDKVGASASDGSVCVLDL 500 510 520 >>CCDS48078.1 TBL1X gene_id:6907|Hs108|chrX (526 aa) initn: 354 init1: 150 opt: 369 Z-score: 331.7 bits: 70.4 E(32554): 3.7e-12 Smith-Waterman score: 405; 34.0% identity (53.7% similar) in 259 aa overlap (11-221:234-481) 10 20 30 40 pF1KB3 MKDSLVLLGRVPAHPDSRCWFLAWNPAGTLLASCGGDRRI ::.. : : :: :::::. . : CCDS48 TARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTS--LDWNTNGTLLATGSYDGFA 210 220 230 240 250 260 50 60 70 80 90 pF1KB3 RIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWK------KNQDD ::: .:. :.:.. :. . . :. :::. ::. : :: :: :.: CCDS48 RIWTEDGN---LASTLGQ-HKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFP 270 280 290 300 310 100 110 120 pF1KB3 FE-----------------C----------------VTTLEGHENEVKSVAWAPSGNLLA :. : : :..:: :::... : ::: ::: CCDS48 FHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLA 320 330 340 350 360 370 130 140 150 160 170 pF1KB3 TCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHP---------SQELLASASYDD .:: : .. .: . .: :. :..:.... . : : :. .:::::.:. CCDS48 SCSDDMTLKIWSMKQE---VCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDS 380 390 400 410 420 430 180 190 200 210 220 230 pF1KB3 TVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIWRQYLPGNEQGV ::.:. :. :: :: :. :.:.::.:.:. ::: : :. :.:: CCDS48 TVRLWDIERG--VCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSY 440 450 460 470 480 490 240 250 260 270 280 290 pF1KB3 ACSGSDPSWKCICTLSGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDPQQPTF CCDS48 RGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK 500 510 520 >>CCDS14133.1 TBL1X gene_id:6907|Hs108|chrX (577 aa) initn: 354 init1: 150 opt: 369 Z-score: 331.1 bits: 70.4 E(32554): 4e-12 Smith-Waterman score: 405; 34.0% identity (53.7% similar) in 259 aa overlap (11-221:285-532) 10 20 30 40 pF1KB3 MKDSLVLLGRVPAHPDSRCWFLAWNPAGTLLASCGGDRRI ::.. : : :: :::::. . : CCDS14 TARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTS--LDWNTNGTLLATGSYDGFA 260 270 280 290 300 310 50 60 70 80 90 pF1KB3 RIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWK------KNQDD ::: .:. :.:.. :. . . :. :::. ::. : :: :: :.: CCDS14 RIWTEDGN---LASTLGQ-HKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFP 320 330 340 350 360 100 110 120 pF1KB3 FE-----------------C----------------VTTLEGHENEVKSVAWAPSGNLLA :. : : :..:: :::... : ::: ::: CCDS14 FHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLA 370 380 390 400 410 420 130 140 150 160 170 pF1KB3 TCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHP---------SQELLASASYDD .:: : .. .: . .: :. :..:.... . : : :. .:::::.:. CCDS14 SCSDDMTLKIWSMKQE---VCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDS 430 440 450 460 470 480 180 190 200 210 220 230 pF1KB3 TVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIWRQYLPGNEQGV ::.:. :. :: :: :. :.:.::.:.:. ::: : :. :.:: CCDS14 TVRLWDIERG--VCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSY 490 500 510 520 530 540 240 250 260 270 280 290 pF1KB3 ACSGSDPSWKCICTLSGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDPQQPTF CCDS14 RGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK 550 560 570 >>CCDS32528.1 PAFAH1B1 gene_id:5048|Hs108|chr17 (410 aa) initn: 391 init1: 155 opt: 342 Z-score: 310.1 bits: 66.0 E(32554): 6e-11 Smith-Waterman score: 374; 32.0% identity (58.3% similar) in 228 aa overlap (14-221:149-365) 10 20 30 40 pF1KB3 MKDSLVLLGRVPAHPDSRCWFLAWNPAGTLLASCGGDRRIRIW : :: .... .: :::::..: :..: CCDS32 VFSVMVSASEDATIKVWDYETGDFERTLKGHTDS-VQDISFDHSGKLLASCSADMTIKLW 120 130 140 150 160 170 50 60 70 80 90 100 pF1KB3 GTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEG .: . : .. .::...: .:: : :....::: : : .:. : . :: :. : CCDS32 DFQG--FECIRTM-HGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV-QTGY-CVKTFTG 180 190 200 210 220 230 110 120 130 140 150 160 pF1KB3 HENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQE :.. :. : .:.:.:.:: :..: :: : . :: . : : . :. . : : . CCDS32 HREWVRMVRPNQDGTLIASCSNDQTVRVWVVATK---ECKAELREHEHVVECISWAPESS 240 250 260 270 280 170 180 190 200 pF1KB3 --------------------LLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFD .: :.: : :.:.. . . .: :: ::.. : .. : CCDS32 YSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW--DVSTGMCLMTLVGHDNWVRGVLFH 290 300 310 320 330 340 210 220 230 240 250 260 pF1KB3 PSGQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCICTLSGFHSRTIYDIAWCQL .:. . ::.::.:.:.: CCDS32 SGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 350 360 370 380 390 400 339 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:20:53 2016 done: Fri Nov 4 02:20:53 2016 Total Scan time: 2.680 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]